CN108076254A - A kind of imaging device for colorimetric sensor array - Google Patents

A kind of imaging device for colorimetric sensor array Download PDF

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Publication number
CN108076254A
CN108076254A CN201610994032.7A CN201610994032A CN108076254A CN 108076254 A CN108076254 A CN 108076254A CN 201610994032 A CN201610994032 A CN 201610994032A CN 108076254 A CN108076254 A CN 108076254A
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sensor array
lens
imaging device
top plate
colorimetric sensor
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CN201610994032.7A
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CN108076254B (en
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孟虎
冯亮
李慧
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Dalian Institute of Chemical Physics of CAS
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Dalian Institute of Chemical Physics of CAS
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    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04NPICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N23/00Cameras or camera modules comprising electronic image sensors; Control thereof
    • H04N23/50Constructional details
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04NPICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N23/00Cameras or camera modules comprising electronic image sensors; Control thereof
    • H04N23/50Constructional details
    • H04N23/54Mounting of pick-up tubes, electronic image sensors, deviation or focusing coils
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04NPICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N23/00Cameras or camera modules comprising electronic image sensors; Control thereof
    • H04N23/50Constructional details
    • H04N23/55Optical parts specially adapted for electronic image sensors; Mounting thereof
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04NPICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N23/00Cameras or camera modules comprising electronic image sensors; Control thereof
    • H04N23/56Cameras or camera modules comprising electronic image sensors; Control thereof provided with illuminating means

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  • Engineering & Computer Science (AREA)
  • Multimedia (AREA)
  • Signal Processing (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

The present invention relates to a kind of imaging devices for colorimetric sensor array, belong to technical field of analytical instruments.The imaging device includes miniature CMOS camera, top plate, barrel, micro-lens, wide-angle lens, screw rod, guide rod, screw rod cutting ferrule, housing, colorimetric sensor array, intermediate plate, White LED light filling plate and bottom plate.The imaging device passes through the reasonable selection between miniature CMOS camera, micro-lens and wide-angle lens and collocation, the design of White LED area source light filling plate, and in mechanical structure each focal length reasonable adjusting, realize contrastive colours sensor array closely, high-resolution imaging, can capture be carried out with the huge scanner contrastive colours sensor array of substituted volume completely.The present apparatus have many advantages, such as high resolution, it is small, at low cost, using easy, easy to carry, therefore, especially suitable for the field quick detection instrument based on colorimetric principle and other to be closely elder generation and the higher occasion of resolution requirement.

Description

A kind of imaging device for colorimetric sensor array
Technical field
The invention belongs to technical field of analytical instruments, are filled more particularly to a kind of imaging for colorimetric sensor array It puts.
Background technology
In fields such as public safety, environmental monitoring, medicine detections in the prevalence of to quick, sensitive, high-throughput, miniaturization The demand of detecting instrument.Sensor array based on array analysis employs the sensing modes of manual simulation's olfactory system, It is obtained while can realizing multiple spot information in plane, drastically increases analysis efficiency and detection flux, to minimize instrument Development provide new opportunity.Wherein, photochemistry colorimetric sensor array with its is cheap, method is simple, response quickly, The advantages that containing much information has obtained increasingly extensive application.Generally use spectrum or imaging two ways are to photochemistry colorimetric battle array The optical signalling progress of all sensing units gathers simultaneously in sensor.Although spectral technique is comprising containing much information but need to compare More complicated instrument and equipment is also required to certain time to the acquisition of each sensing unit data, therefore is not particularly suited for mutually turning down Type instrument.Compared with spectral technique, imaging technique has and can detect multiple sensor units within sweep of the eye given Advantage, and imaging technique is simpler than spectral technique, and especially complex instrument and equipment is not required.
The imaging device for being generally used for photochemistry colorimetric sensor array mainly has flat bed scanner, digital camera, hand Machine camera etc..Although flat bed scanner imaging effect is good, its is bulky, significantly limits the micromation of pertinent instruments Design;And although it is more convenient that the first-class contrastive colours sensor array of digital camera, cell-phone camera is used to be imaged, and is easily subject to The interference of focal length, shooting angle, ambient intensity etc., the stability and poor repeatability of acquired results.
Therefore, how a kind of imaging device available for photochemistry colorimetric sensor array is provided, while meets resolution ratio It is high, small, at low cost, using easy, requirement easy to carry, be those skilled in the art's technical issues that need to address.
The content of the invention
To solve the above-mentioned problems, the object of the present invention is to provide a kind of imaging device for colorimetric sensor array, The requirements of the related miniaturization instrument based on colorimetric principle can fully be met.
The technical scheme is that:
A kind of imaging device for colorimetric sensor array:Described device includes miniature CMOS camera, top plate, camera lens Cylinder, micro-lens, wide-angle lens, screw rod, guide rod, screw rod cutting ferrule, housing, colorimetric sensor array, intermediate plate, White LED Light filling plate and bottom plate.
1) hollow housing of upper and lower opening;Lower section is set
2) it is equipped with the intermediate plate of colorimetric sensor array;Lower section is set
3) it is equipped with the bottom plate of White LED light filling plate;
Wherein, mainly it is made of in housing top plate and barrel, barrel is arranged on the lower section of top plate;Top plate is equipped with window Mouthful, miniature CMOS camera is equipped at window;Barrel is internally provided with micro-lens and wide-angle lens.
Inner walls face is equipped with the guide rod (being preferably that two guide rods are symmetrical arranged) of at least two protrusions, top plate vertically Side wall surface correspondence position is equipped with groove, and the groove is suitable with guide rod size, and guide rod is used to make top plate and barrel in shell Keep vertical when moving up and down in vivo, spiral shell has dismountable screw rod cutting ferrule on housing upper internal face, and screw rod cutting ferrule is located at top plate On, screw rod cutting ferrule and top plate diametrically opposite position are provided with tapped through hole, and screw rod is led to by the screw thread on screw rod cutting ferrule and top plate Hole rotational movement top plate and barrel move up and down in housing, and the barrel is fixed by screw and top plate.
The position of micro-lens is close to top plate one side in barrel, and the position of wide-angle lens is away from top plate one side, institute State that micro-lens is opposite with wide-angle lens to be placed in parallel.
The guide rod is detachable, is fixed on housing sidewall by screw.
It is hollowed out among the intermediate plate, places colorimetric sensor array, the colorimetric sensor array includes transparent anti- Answer kit, colorimetric sensor array film, colorimetric sensor array film is placed in reaction kit, on film it is immobilized have can with it is to be measured The indicator that analyte reacts;
Intermediate plate side wall is laterally opened there are two through hole, is inserted into be passed through the inlet tube and outlet of test analyte;
The bottom plate is equipped with the groove suitable with hollowing out size among intermediate plate, position is identical, and White LED light filling plate is placed in In the groove of bottom plate.
Intermediate plate, bottom plate and housing are affixed by screw;
The White LED light filling plate is made by multiple LED lamp beads or LED area light source.
The reaction kit is equipped with handle, and the material of the colorimetric sensor array film is polyvinylidene fluoride film, polychlorostyrene One kind in vinyl film, polyester film, makrolon, acetyl cellulose film, filter paper, using polymer or sol-gel method In immobilized indicator on colorimetric sensor array film.Polymer or molten may be employed in immobilized indicator on colorimetric sensor array film Gluing method be gelled (see Chinese patent:102466638B), the test analyte refers to chromogenic reaction can occur with indicator Analysans.
White LED light filling plate uniformly provides the light softening that LED is sent to visible ray light filling for colorimetric sensor array afterwards and shines Bright, miniature CMOS camera becomes defocused with wide-angle lens by micro-lens and gathers image into colorimetric sensor array.
The magnifying power of the micro-lens is 1:1~1:10, the extensive angle of wide-angle lens is 0.2~0.7.
A kind of scheme is provided, the spiro rod length is 20mm~60mm;The body height is 30mm~80mm, miniature (camera is placed in top plate window, can be arranged on camera for 0~5mm for the distance between CMOS camera and micro-lens It is kept with top plate bottom in a plane, it is 0) micro-lens and wide-angle lens to make the distance between camera and micro-lens The distance between 0~10mm, 0~50mm of the distance between wide-angle lens and colorimetric sensor array.
On the distance between each camera lens, debugged according to actual needs.
The colorimetric sensor array film refers to the sensor array being made of a variety of indicator.
The imaging device of the present invention is not restricted to square body, can also be tubular or other shapes.
The camera of the imaging device can be connected by winding displacement with microcomputer, and microcomputer sends the commands to control and takes As the time and image is recorded, comes out image display finally by the display screen for being connected to microcomputer.
Beneficial effects of the present invention are:
The present invention is by the reasonable selection between miniature CMOS camera, micro-lens and wide-angle lens and collocation, in vain The reasonable adjusting of each focal length, realizes contrastive colours sensor array in the design and mechanical structure of color LED area light source light filling plate Closely, high-resolution imaging, completely can be huge with substituted volume and from external interference, stability and reproducible Imaging device of the scanner as colorimetric sensor array.High resolution of the present invention, it is small, at low cost, use it is easy, carry It is convenient, especially suitable for the field quick detection instrument based on colorimetric principle and other with closely for elder generation and resolution requirement Higher occasion.
Description of the drawings
Fig. 1 is a kind of image device structure schematic diagram for colorimetric sensor array, wherein, 1 images for miniature CMOS Head, 2 be top plate, 3 be barrel, 4 be micro-lens, 5 be wide-angle lens, 6 be screw rod, 7 be guide rod, 8 be screw rod cutting ferrule, 9 It is colorimetric sensor array for housing, 10,11 be intermediate plate, 12 be White LED light filling plate, 13 is bottom plate.
Fig. 2 is that scanner is schemed with herein described imaging device degree sensor array imaging contrast.
Fig. 3 is to being passed through 100ppm SO using imaging device described in Fig. 12The methyl red colorimetric sensor of gas is every one Minute carries out a capture, and the result figure extracted with Photoshop softwares to the rgb value of image.
Fig. 4 is to being passed through the SO of various concentration using imaging device described in Fig. 12The bromocresol purple colorimetric sensor of gas into Row takes color, and is used for SO obtained from being extracted with Photoshop softwares to the rgb value of image2The standard curve of detection.
Fig. 5 be utilize imaging device described in Fig. 1 to be used to detecting the sensor of ziram to the ziram of various concentration into Sensor carries out image during row detection, and it is beautiful to be used for good fortune obtained from being extracted with Photoshop softwares to the rgb value of image The standard curve of zinc detection.
Specific embodiment
Next with reference to the accompanying drawings and examples the present invention will be described in detail, herein illustrative examples and explanation of the invention For explaining the present invention, but it is not as a limitation of the invention.
Embodiment 1
As shown in Figure 1, be a kind of image device structure schematic diagram for colorimetric sensor array, it is described can be used for than The imaging device of color sensor array is by miniature CMOS camera 1, top plate 2, barrel 3, micro-lens 4, wide-angle lens 5, spiral shell Bar 6, guide rod 7, screw rod cutting ferrule 8, housing 9, colorimetric sensor array 10, intermediate plate 11, White LED light filling plate 12 and bottom plate 13 compositions.
The hollow housing 9 of upper and lower opening;Lower section is equipped with the intermediate plate 11 of colorimetric sensor array 10;Lower section is equipped with white The bottom plate 13 of LED light fillings plate 12;
Wherein, mainly it is made of in housing 9 top plate 2 and barrel 3, barrel 3 is arranged on the lower section of top plate 2;Top plate 2 is set There is window, miniature CMOS camera 1 is equipped at window;Barrel 3 is internally provided with micro-lens 4 and wide-angle lens 5.
9 internal face of housing is vertically symmetrical to be set there are two the guide rod 7 of protrusion, and 2 side wall surface correspondence position of top plate is equipped with groove, The groove is suitable with 7 size of guide rod, and guide rod 7 is used to keep when top plate 2 and barrel 3 being made to move up and down in housing 9 Vertically, spiral shell has dismountable screw rod cutting ferrule 8 on 9 upper inside wall face of housing, and screw rod cutting ferrule 8 is located on top plate, 8 He of screw rod cutting ferrule 2 diametrically opposite position of top plate is provided with tapped through hole, and screw rod passes through the tapped through hole rotary motion band on screw rod cutting ferrule 8 and top plate 2 Dynamic top plate 2 and barrel 3 move up and down in housing 9, and the barrel 3 is fixed by screw and top plate 2.
The position of micro-lens 4 is close to 2 one side of top plate in barrel 3, and the position of wide-angle lens 5 is away from top plate 2 one Side, the micro-lens 4 is opposite with wide-angle lens 5 to be placed in parallel.
The guide rod 7 is detachable, is fixed on 9 side wall of housing by screw.
It is hollowed out among the intermediate plate 11, places colorimetric sensor array 10, the colorimetric sensor array 10 includes band Transparent reaction kit, the colorimetric sensor array film of handle, colorimetric sensor array film is placed in reaction kit, on film Immobilized to have the indicator that reacted with test analyte, the reaction kit is equipped with handle, the colorimetric array sensing The material of device film is polyvinylidene fluoride film, in polychloroethylene film, polyester film, makrolon, acetyl cellulose film, filter paper One kind, using polymer or sol-gel method in immobilized indicator on colorimetric sensor array film.
11 side wall of intermediate plate laterally opens the inlet tube and outlet for there are two through hole, being inserted into test analyte;
The bottom plate 13 is equipped with hollowing out the groove that size is suitable, position is identical, White LED light filling plate among intermediate plate 11 12 are placed in the groove of bottom plate 13.
Intermediate plate 11, bottom plate 13 and housing 9 are affixed by screw;
The White LED light filling plate 12 is made by LED area light source.
White LED light filling plate 12 uniformly provides the light softening that LED is sent to visible ray for colorimetric sensor array 10 afterwards and mends Optical illumination, miniature CMOS camera 1 become defocused into 10 acquisition figure of colorimetric sensor array by micro-lens 4 with wide-angle lens 5 Picture.
The magnifying power of micro-lens 4 is 1:5, the extensive angle of wide-angle lens 5 is 0.65.
6 length of screw rod is 40mm.
9 height of housing is 50mm.
The distance between miniature CMOS camera 1, micro-lens 4, wide-angle lens 5 and colorimetric sensor array 10 pass through ratio The imaging effect of color sensor array determines, principle is to ensure that the imaging clearly, undeformed and can will of colorimetric sensor array Sensor is all shown, such as when the distance between wide-angle lens and colorimetric sensor array are 10mm, corresponds to microspur The distance between camera lens and wide-angle lens are 5mm, and when the distance between micro-lens and wide-angle lens 0mm, imaging effect is optimal; And when the distance between wide-angle lens and colorimetric sensor array are 5mm, between corresponding micro-lens and wide-angle lens away from From for 10mm, when the distance between micro-lens and wide-angle lens 2mm, imaging effect is optimal.
Application examples 1
The sensor array of the 6x6 being made of 36 kinds of indicator prepared is taken, respectively with institute in scanner and embodiment 1 It states imaging device and capture is carried out to it, image is shown in Fig. 2, from figure 2 it can be seen that imaging device is with sweeping described in embodiment 1 It is the same to retouch the image of instrument acquisition, illustrates that the imaging device can substitute capture of the scanner for colorimetric sensor completely.
The camera of the imaging device is connected by winding displacement with Raspberry Pi computer Raspberry Pi, Raspberry Pi computer It sends the commands to the control capture time and records image, finally by the model 7inch HDMI for being connected to Raspberry Pi computer LCD (B) display screen comes out image display.
Application examples 2
Instruction methyl red 4mg is weighed, is put into 1.5mL centrifuge tubes, 1mL sol gel solutions are then added in into centrifuge tube (preparation method of collosol and gel is:Tetraethoxysilane:Normal octane triethoxysilane:Ethylene glycol monomethyl ether:Propylene glycol monomethyl ether vinegar Acid esters:Acetonitrile:0.1M hydrochloric acid:Polysorbas20:Water is with 0.5:0.6:3.5:1.4:0.45:0.35:0.03:1 volume ratio mixes 10mL solution when water at normal temperature solution 16 is small, obtains sol gel solution), add in that concentration is 0.2M after ultrasonic dissolution thereto six 30 microlitres of methenamine shakes mixing, and polyvinyl chloride of the 2 microlitres of drop coatings of indicator solution at 0.45 micron is drawn with liquid-transfering gun On film, put it into after organic solvent volatilization completely in the closed container being protected from light, the lower room temperature of nitrogen environment protection is kept in dark place, It is spare.The immobilized film for having indicator is taken, is cut into and transparent small cassette bottom (material of transparent capsule can be plastics) size Comparable size is placed in capsule bottom, buckle closure, and four sides are sealed with box body, the SO that must be prepared2Gas sensor.Take preparation Good sensor is placed in imaging device, be connected to by the test analyte inlet tube of intermediate plate 11 in gas piping and to its In be passed through flow velocity as 300mL/min, relative humidity 30%, concentration is respectively the SO of 100ppm2Gas 10min, in the process Imaging device carries out capture described in above-described embodiment 1, is taken every one minute once as the camera of imaging device passes through row Line is connected with Raspberry Pi computer Raspberry Pi, and Raspberry Pi computer sends the commands to the control capture time and records image, Image display is come out finally by model 7inch HDMI LCD (B) display screen for being connected to Raspberry Pi computer, then to obtaining The image obtained is carried out taking color with Photoshop softwares, is obtained with SO2The RGB of the indicator color being passed through in sensor of gas The initial RGB values of indicator color and itself and are carried out subtractive by value, so as to obtain color change value △ R, the △ G of indicator with And △ B, utilize formulaIt is calculated and changes over time indicator color value and must change Situation, the results are shown in Figure 3, the results show that can be good at obtaining with SO using the imaging device2Gas is passed through instruction The color change situation of agent.
Application examples 3
Indicator bromocresol purple 2mg is weighed, is put into 1.5mL centrifuge tubes, 1mL collosol and gels are then added in into centrifuge tube (preparation method of collosol and gel is solution:Octane triethoxysilane:(3- mercaptopropyis) trimethoxy silane:Ethylene glycol first Ether:Propylene glycol methyl ether acetate:Dichloroethanes:0.1M hydrochloric acid:Cetyl trimethylammonium bromide:Water is with 0.5:0.6:3.5: 1.4:0.45:0.35:0.03:1 volume ratio mixes to obtain 10mL solution, when water at normal temperature solution 24 is small, obtains sol gel solution)), surpass 20 microlitres of the potassium hydroxide that concentration is 0.1M is added in after sound dissolving thereto, shakes mixing, indicator solution 2 is drawn with liquid-transfering gun Filter paper is put into after organic solvent volatilization completely in the closed container being protected from light by microlitre drop coating on No. 41 filter paper of whatman, The lower room temperature of nitrogen environment protection is kept in dark place, is spare.The immobilized filter paper for having indicator is taken, is cut into and transparent small cassette bottom (material of transparent capsule can be plastics) comparable size of size is placed in capsule bottom, buckle closure, and four sides are sealed with box body, The sensor that must be prepared.The sensor prepared is taken to be placed in imaging device, passes through the test analyte import of intermediate plate 11 Pipe is connected in gas piping and is passed through flow velocity thereto as 300mL/min, and humidity 30%, concentration is respectively 12.5,18.75, 25,32.5,38.75ppm SO2Gas 3min, and described in embodiment 1 imaging device to being passed through SO2Sensor before and after gas It carries out taking color, the camera of the imaging device can be connected by winding displacement with Raspberry Pi computer Raspberry Pi, Raspberry Pi electricity Instruction can be transmitted to control the capture time and record image, finally by the model 7inch for being connected to Raspberry Pi computer in brain HDMI LCD (B) display screen comes out image display, then the image of acquisition is carried out with Photoshop softwares to take color, is passed The rgb value of sensor internal indicator color, and by the initial RGB values of indicator color and it is passed through SO2Carry out subtractive afterwards, so as to To color change value △ R, △ G and the △ B of indicator, formula is utilizedIt calculates To being passed through various concentration SO2The color change value of indicator after gas, wherein, ED is Euclidean distance (euclidean Metric), the results are shown in Figure 3, the results show that indicator methyl red and the mixture of bromocresol purple to concentration in 12.5- SO between 38.75ppm2Gas has good linear relationship, wherein R2=0.998, linear equation y=1.2813x- 0.2337, wherein R2For fitting coefficient, x represents SO2Concentration, y represent to being passed through SO2Sensor before and after gas carries out taking color, And △ R, △ G and the △ B that subtractive obtains are carried out to it, then utilize formulaIt calculates The value arrived.The imaging device, which is can be seen that, from above-mentioned experimental result can be used for toxic gas based on colorimetric sensor Detection.
Application examples 4
1- pyridylazos-beta naphthal of 2mg is weighed in 0.5mL silica gel collosol and gel A (tetramethoxy-silicanes:Ethylene glycol first Ether:Propylene glycol methyl ether acetate:Tetrahydrofuran:0.05M sulfuric acid:Polysorbas20:Water is with 1:3:2:0.5:0.8:0.03:0.6 volume Than mixing, when 50 DEG C of hydrolysis 8 are small, silica gel sol gel solution A is obtained) in, then it is above-mentioned to draw 1 μ L with liquid-transfering gun for ultrasonic dissolution Solution, drop coating are prepared into the sensor of pesticide containing heavy metal classes in porous filter paper after the lower drying at room temperature of nitrogen protection.Take preparation Good sensor is respectively 0.5 to concentration is added dropwise thereon, and 1,1.5,2,2.5ppm 400 μ L of ziram aqueous solution treat solution quilt After absorbent filter of the pad below sensor blots, imaging device records image, the camera shooting of the imaging device described in embodiment 1 Head can be connected by winding displacement with Raspberry Pi computer Raspberry Pi, and instruction can be transmitted to control the capture time in Raspberry Pi computer And image is recorded, finally by being connected to model 7inch HDMI LCD (B) display screens of Raspberry Pi computer by image display Out, using the sensor of 400 μ L pure water of enrichment as image before reacting, after being enriched with the sensor of each concentration ziram solution as reaction Image by imagery exploitation Photoshop software digitals before and after reaction, extracts RGB (RGB) channel value, and to reaction before and after Each passage color data carries out subtractive, obtains each passage color change value △ R, △ G, △ B, then utilizes formulaSensor and the color change value before and after each concentration ziram solution reaction is calculated ED, as shown in Figure 4.The results show that with the increase of ziram concentration, sensor colors variation enhancing.By color change value ED Figure is done with ziram concentration, obtains the standard curve of the sensor of pesticide containing heavy metal classes detection ziram pesticide, y=28.79x+ 15.01(R2=0.989), it is seen then that between the concentration range internal indicator color change of 0.5~2.5ppm and ziram concentration With good linear relationship, illustrate that the imaging device can be used in colorimetric method for determining pesticide aspect.

Claims (10)

1. a kind of imaging device for colorimetric sensor array, it is characterised in that:Including:
1) hollow housing (9) of upper and lower opening;Lower section is set
2) it is equipped with the intermediate plate (11) of colorimetric sensor array (10);Lower section is set
3) it is equipped with the bottom plate (13) of White LED light filling plate (12);
Wherein, mainly it is made of in housing (9) top plate (2) and barrel (3), barrel (3) is arranged on the lower section of top plate (2); Top plate (2) is equipped with window, and miniature CMOS camera (1) is equipped at window;Barrel (3) is internally provided with micro-lens (4) and wide Angle mirror head (5).
2. imaging device according to claim 1, it is characterised in that:It is convex that housing (9) internal face is equipped at least two vertically The guide rod (7) risen, top plate (2) side wall surface correspondence position are equipped with groove, and the groove is suitable with guide rod (7) size, are oriented to Bar (7) is for making top plate (2) and barrel (3) be kept when being moved up and down in housing (9) vertically, housing (9) upper inside wall face Upper spiral shell has dismountable screw rod cutting ferrule (8), and screw rod cutting ferrule (8) is located on top plate, screw rod cutting ferrule (8) and top plate (2) radial direction phase Tapped through hole is provided with to position, screw rod passes through the tapped through hole rotational movement top plate on screw rod cutting ferrule (8) and top plate (2) (2) moved up and down with barrel (3) in housing (9), the barrel (3) is fixed by screw and top plate (2).
3. imaging device according to claim 1, it is characterised in that:In barrel (3) position of micro-lens (4) be by Nearly top plate (2) one side, the position of wide-angle lens (5) is away from top plate (2) one side, the micro-lens (4) and wide-angle lens (5) It is opposite to be placed in parallel.
4. imaging device according to claim 2, it is characterised in that:
The guide rod (7) detachably, by screw is fixed on housing (9) side wall.
5. imaging device according to claim 1, it is characterised in that:
It is hollowed out among the intermediate plate (11), places colorimetric sensor array (10), the colorimetric sensor array (10) includes Transparent reaction kit, colorimetric sensor array film, colorimetric sensor array film is placed in reaction kit, immobilized on film to have The indicator that can be reacted with test analyte;
Intermediate plate (11) side wall is laterally opened there are two through hole, is inserted into be passed through the inlet tube and outlet of test analyte;
The bottom plate (13) is equipped with hollowing out the groove that size is suitable, position is identical, White LED light filling plate among intermediate plate (11) (12) it is placed in the groove of bottom plate (13).
6. imaging device according to claim 1 or 5, it is characterised in that:
Intermediate plate (11), bottom plate (13) and housing (9) are affixed by screw;
The White LED light filling plate (12) is made by multiple LED lamp beads or LED area light source.
7. imaging device according to claim 1 or 5, it is characterised in that:
The reaction kit is equipped with handle, and the material of the colorimetric sensor array film is polyvinylidene fluoride film, polyvinyl chloride One kind in film, polyester film, makrolon, acetyl cellulose film, filter paper, using polymer or sol-gel method in than Immobilized indicator on color sensor array film.
8. imaging device according to claim 1, it is characterised in that:The light that White LED light filling plate (12) sends LED is soft The illumination of visible ray light filling is provided for colorimetric sensor array (10) after changing uniformly, miniature CMOS camera (1) passes through micro-lens (4) become defocused with wide-angle lens (5) and gather image into colorimetric sensor array (10).
9. the imaging device according to claim 1 or 7, it is characterised in that:The magnifying power of the micro-lens (4) is 1:1 ~1:10, the extensive angle of wide-angle lens (5) is 0.2~0.7.
10. imaging device according to claim 1, it is characterised in that:Screw rod (6) length is 20mm~60mm;Institute Housing (9) is stated highly for 30mm~80mm, the distance between miniature CMOS camera and micro-lens are 0~5mm, micro-lens The distance between wide-angle lens 0~10mm, 0~50mm of the distance between wide-angle lens and colorimetric sensor array.
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