CN108057125A - Smelly eliminating composition or masking composition and their application method - Google Patents
Smelly eliminating composition or masking composition and their application method Download PDFInfo
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- CN108057125A CN108057125A CN201711090588.4A CN201711090588A CN108057125A CN 108057125 A CN108057125 A CN 108057125A CN 201711090588 A CN201711090588 A CN 201711090588A CN 108057125 A CN108057125 A CN 108057125A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
- A61L9/01—Deodorant compositions
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
- A23L5/20—Removal of unwanted matter, e.g. deodorisation or detoxification
- A23L5/27—Removal of unwanted matter, e.g. deodorisation or detoxification by chemical treatment, by adsorption or by absorption
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- General Preparation And Processing Of Foods (AREA)
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Abstract
The present invention is a kind of smelly eliminating composition or masking composition and their application method.It is an object of the present invention to improve the foreign odor of specific deodorizing ingredient, useful smelly eliminating composition is provided.The foreign odor of foregoing deodorizing ingredient can be sheltered or reduced with the specific compound that foregoing deodorizing ingredient has similar chemical constitution.
Description
Technical field
It is used the present invention relates to the smelly eliminating that the foreign odor of deodorizing ingredient is minimized with composition and using foregoing smelly eliminating
Composition, the method for reducing object peculiar smell.Moreover, it relates to the masking composition of the foreign odor of deodorizing ingredient,
And the covering method of the foreign odor of the deodorizing ingredient of foregoing masking composition is used.
Background technology
In recent years, as from deodorant be able to it is widely available and be appreciated that, cleaning purpose improve, take notice of life it is different
The people of taste or body odour etc. is more.In addition, newly-built building, new car compartment in, because can result in dizzy building syndrome etc.
Volatile materials and generate unique peculiar smell, the people not felt well to this peculiar smell is also more, has carried out largely related with peculiar smell grind
Study carefully.
For each glomerulus (yarn sphere) of olfactory bulb probably there are a kind of osmoreceptor, glomerulus can be by with common
A variety of smell substances of characterization of molecules activate (non-patent literature 1).With the similar region for experiencing molecule, (molecule is held
Ke Neng Collar domains) glomerulus be present in each other nearby and form cluster and sub- cluster (non-patent literature 1).In addition, patent is literary
1 is offered to describe：The compounds such as 2,4,6- Trichloroanisoles (TCA) and 2,4,6- tribromos anisole (TBA) are by hindering smell thin
Cationic channel on born of the same parents and make the sensitivity decrease of smell, thus given play to smelly eliminating effect.
Prior art literature
Patent document
Patent document 1：Japanese Unexamined Patent Publication 2013-147475 publications
Non-patent literature
Non-patent literature 1：Takahashi YK etc., Journal of Neurophysiology (2004), Vol.92,
pp.2413-2427
The content of the invention
Problems to be solved by the invention
However, the deodorizing ingredients itself such as TCA and TBA have fustiness, therefore not yet it is fully applicable to smelly eliminating composition.This
The purpose of invention is, improves the foreign odor of foregoing deodorizing ingredient, provides useful smelly eliminating composition.
The method for solving problem
The inventors of the present invention have made intensive studies in order to solve the above problems, it turns out that：With the smelly eliminatings such as TCA and TBA
Ingredient has the foreign odor that deodorizing ingredient can be sheltered or reduced to the specific compound of similar chemical constitution, so as to complete this
Invention.
That is, the present invention provides smelly eliminating composition described below or masking composition and their application method.
(1) a kind of smelly eliminating composition, it includes：At least one kind of compound and following formula (2) shown in following formula (1)
Shown at least one kind of compound.
(in formula, R1~R5It is same or different to each other, represents hydrogen atom, halogen atom or the hydrocarbon optionally with substituent group
Base, R1~R5In at least one be halogen atom)
(in formula, R6~R10It is same or different to each other, represents hydrogen atom, hydroxyl, alkoxy or alkyl)
(2) the smelly eliminating composition according to foregoing (1), wherein, at least one kind of compound shown in previously described formula (1) is
2,4,6- Trichloroanisoles and/or 2,4,6- tribromo anisoles.
(3) the smelly eliminating composition according to foregoing (1) or (2), wherein, in previously described formula (2), R6And R9For hydrogen atom,
R7、R8And R10For hydroxyl, alkoxy or alkyl.
(4) the smelly eliminating composition according to any one of foregoing (1)~(3), wherein, shown in previously described formula (2) extremely
Few a kind of compound is selected from by anisole, veratrole (ベ ラ ト ロ ー Le), estragole (エ ス ト ラ ゴ ー Le), guaiacol (グ
ア ヤ コ ー Le), 4-ethyl guaiacol, hydroquinone dimethyl ether, anethole, resorcin dimethyl ether, methyl phenol (Network レ
オ ゾ ー Le) and p-tolyl methyl ether composition one or more of group.
(5) the smelly eliminating composition according to any one of foregoing (1)~(4), wherein, shown in previously described formula (2) extremely
The content of few a kind of compound is 1 times or more of the content of at least one kind of compound shown in previously described formula (1).
(6) the smelly eliminating composition according to any one of foregoing (1)~(5), wherein, shown in previously described formula (1) extremely
The mass concentration of few a kind of compound is more than 1ppq.
(7) a kind of deodorant accommodates the smelly eliminating composition any one of foregoing (1)~(6).
(8) a kind of resin or building materials, it includes the smelly eliminating compositions any one of foregoing (1)~(6).
(9) a kind of beverage/food additive or beverage/food, it includes the smelly eliminatings any one of foregoing (1)~(6)
Use composition.
(10) a kind of peculiar smell is prevented and kill off with product, and it includes the smelly eliminating compositions any one of foregoing (1)~(6).
(11) a kind of method for reducing object peculiar smell, which is characterized in that it includes：Make aforementioned object or including aforementioned object
Space or composition in the process containing the smelly eliminating composition any one of foregoing (1)~(6).
(12) a kind of masking composition, which is characterized in that it is at least one kind ofization for sheltering shown in following formula (1)
The composition of the foreign odor of object is closed, it includes at least one kind of compound shown in following formula (2),
(in formula, R1~R5It is same or different to each other, represents hydrogen atom, halogen atom or the hydrocarbon optionally with substituent group
Base, R1~R5In at least one be halogen atom)
(in formula, R6~R10It is same or different to each other, represents hydrogen atom, hydroxyl, alkoxy or alkyl)
(13) the masking combination described in the smelly eliminating composition or foregoing (12) any one of foregoing (1)~(6)
Object is prevented and kill off in manufacture deodorant, resin, building materials, beverage/food additive, beverage/food or peculiar smell with the application in product.
(14) masking composition described in foregoing (12) for sheltering or reduce formula (1) institute defined in foregoing (12)
The application of the foreign odor at least one kind of compound shown.
The effect of invention
According to the present invention, by using the compound of previously described formula (2), it can shelter or reduce the compound of previously described formula (1)
Foreign odor.Therefore, it is possible to develop deodorant of the smelly eliminating for the compound for applying previously described formula (1) effect etc..
Specific embodiment
Hereinafter, the present invention is described in more detail.
The smelly eliminating of the present invention includes at least one kind of compound shown in following formula (1) with composition.
(in formula, R1~R5It is same or different to each other, represents hydrogen atom, halogen atom or the hydrocarbon optionally with substituent group
Base, R1~R5In at least one be halogen atom).The compound of previously described formula (1) can hinder the cationic channel of olfactory cell, as
Deodorizing ingredient and play a role (in short, with reference to Japanese Unexamined Patent Publication 2003-147475 publications).
R1~R5Shown halogen atom can be such as fluorine atom, chlorine atom, bromine atoms or iodine atom.
R1~R5Shown alkyl is not particularly limited, and can be such as alkyl, cycloalkyl, cycloalkyl-alkyl, aryl or virtue
Alkyl.Foregoing alkyl can have 1~5 identical or different substituent group.
R1~R5Shown aforesaid alkyl can be such as carbon number 1~20, be preferably carbon number 1~10, be more preferably carbon number 1
~6 straight-chain or the alkyl of branched.
Specifically, aforesaid alkyl can be methyl, ethyl, propyl, isopropyl, butyl, isobutyl group, sec-butyl, tertiary fourth
Base, amyl, isopentyl, neopentyl, hexyl, heptyl, octyl group, nonyl, decyl, undecyl, dodecyl, tridecyl, ten
The straight chains such as tetraalkyl, pentadecyl, cetyl, octadecyl, heptadecyl, octadecyl, nonadecyl and eicosyl
The alkyl of shape or branched.When aforesaid alkyl has substituent group, as its substituent group, it is former that such as alkoxy or halogen may be employed
One or more in sub (fluorine atom, chlorine atom, bromine atoms or iodine atom) etc..
R1~R5Shown foregoing cycloalkyl can be the cycloalkyl of such as carbon number 3~12, can be ring third specifically
Base, cyclobutyl, cyclopenta, cyclohexyl, suberyl, cyclooctyl or adamantyl etc..When foregoing cycloalkyl has substituent group, as
Its substituent group, a kind in may be employed such as alkoxy or halogen atom (fluorine atom, chlorine atom, bromine atoms or iodine atom)
It is or a variety of.
R1~R5Shown foregoing cycloalkyl-alkyl can be the cycloalkyl and carbon number 1~20 for example comprising carbon number 3~12
The cycloalkyl-alkyl of alkyl can be Cvclopropvlmethvl, cyclobutylmethyl, cyclopentyl-methyl or cyclohexyl methyl specifically
Deng.When foregoing cycloalkyl-alkyl has substituent group, as its substituent group, such as alkoxy or halogen atom may be employed, and (fluorine is former
Son, chlorine atom, bromine atoms or iodine atom) etc. in one or more.
R1~R5Shown aforesaid aryl can be the aryl of such as carbon number 6~18, can be phenyl, naphthalene specifically
Base, anthryl, phenanthryl or xenyl etc..When aforesaid aryl has substituent group, as its substituent group, may be employed such as straight-chain or
Alkoxy (the methoxy of the carbon number 1~6 of the alkyl (methyl and tertiary butyl etc.) of the carbon number 1~6 of branched, straight-chain or branched
Base and tert-butoxy etc.) or halogen atom (fluorine atom, chlorine atom, bromine atoms or iodine atom) etc. in one or more.Tool
The aryl of substituted base can be such as p-methylphenyl, tolyl, o-tolyl, 3,5- xylyls, 3,5- di-t-butyls
Phenyl, to tert-butyl-phenyl, p-methoxyphenyl, 3,5- di-t-butyl -4- methoxyphenyls, rubigan, chlorphenyl, right
Fluorophenyl or fluorophenyl etc..
R1~R5Shown foregoing aralkyl can be such as carbon number 7~16 aralkyl, specifically, can be benzyl,
1- phenylethyls, 2- phenylethyls, 1- phenyl propyls, 2- phenyl propyls, 3- phenyl propyls or diphenyl methyl etc..It is foregoing
When aralkyl has substituent group, as its substituent group, such as alkoxy or halogen atom (fluorine atom, chlorine atom, bromine may be employed
Atom or iodine atom) etc. in one or more.
R1~R5The alcoxyl substituted on shown aforesaid alkyl, foregoing cycloalkyl, foregoing cycloalkyl-alkyl and foregoing aralkyl
Base can be such as carbon number 1~15, be preferably carbon number 1~10, the alkoxy of more preferably carbon number 1~6, specifically, can be with
For such as methoxyl group, ethyoxyl, positive propoxy, isopropoxy, n-butoxy, sec-butoxy, isobutoxy, tert-butoxy, penta
Oxygroup or hexyloxy etc..These alkoxies can further have such as halogen atom (fluorine atom, chlorine atom, bromine atoms or iodine
Atom) and carbon number 6~18 the substituent groups such as aryl.
R1~R5Ring can be formed by being selected from arbitrary 2 among them.Foregoing ring can be the yuan of rings of such as 3 yuan of rings~8
Non-aromatic hydrocarbon ring, non-aromatic heterocyclic, aromatic series hydrocarbon ring or heteroaromatic.Foregoing non-aromatic hydrocarbon ring can be such as ring
Alkane ring (cyclopropane ring, cyclobutane ring, pentamethylene ring, cyclohexane ring, cycloheptane ring and cyclooctane ring etc.) or cyclenes hydrocarbon ring
(cyclopentene ring, cyclohexene ring, cycloheptene ring and cyclo-octene ring etc.) etc..Foregoing non-aromatic heterocyclic can be such as tetrahydrochysene -2H-
Pyranoid ring, tetrahydrochysene -2H- thio-pyryliums ring, piperidine ring, dioxanes ring, thioxane ring (オ キ サ チ ア ン Ring), morpholine
Ring, thiomorpholine ring, dithiane ring (ジ チ ア ン Ring), piperazine ring, pyrrolidine ring, thiophane ring, tetrahydrofuran ring, 1,3-
Oxazolidine ring (オ キ サ ゾ ラ ン Ring), dithiolane ring (ジ チ オ ラ ン Ring), oxathiolane ring (オ キ サ チ オ ラ
ン Ring) or dioxolanes etc..Aforementioned fragrance race hydrocarbon ring can be such as phenyl ring.Aforementioned fragrance race heterocycle can be such as furan
Mutter ring, thiphene ring, pyrrole ring, pyridine ring, pyridine ring, pyrimidine ring, pyridazine ring, imidazole ring, pyrazole ring, thiazole ring, oxazole rings or
Isoxazole ring etc..When foregoing ring has substituent group, as its substituent group, such as halogen atom may be employed, and (fluorine atom, chlorine are former
Son, bromine atoms or iodine atom) or the alkyl etc. of carbon number 1~20 in one or more.
On R1~R5, it is preferred that R1、R3And R5For halogen atom, and R2And R4For hydrogen atom.If R1~R5For this
Combination, then the effect of the obstruction cationic channel of the compound of previously described formula (1) is more excellent.
At least one kind of compound shown in previously described formula (1) is preferably halogenated anisole, further preferably 2,4,6- trichlorine fennels
Fragrant ether (TCA) and/or 2,4,6- tribromos anisole (TBA).
The present invention smelly eliminating composition in previously described formula (1) as long as shown at least one kind of compound mass concentration
The effective concentration for playing smelly eliminating effect, is just not particularly limited, can be such as more than 1ppq, be preferably 1ppt with
Upper, more preferably more than 0.1ppb.The upper limit value of the mass concentration of at least one kind of compound shown in previously described formula (1) is not special
It limits, such as can also effectively play a role even if for below 10ppm or below 0.1ppm.
It should be noted that " ppq " (parts per quadrillion described in this specification；1000 parts per trillions 1),
“ppt”(parts per trillion；1 parts per trillion 1), " ppb " (parts per billion；1/1000000000th) and
“ppm”(parts per million；1/1000000th) quality ppq, quality ppt, quality ppb and quality ppm are referred respectively to.
The smelly eliminating composition of the present invention also includes on the basis of comprising at least one kind of compound shown in previously described formula (1)
At least one kind of compound shown in following formula (2).
(in formula, R6~R10It is same or different to each other, represents hydrogen atom, hydroxyl, alkoxy or alkyl)
The compound of previously described formula (2) can play work as the masking ingredient of the foreign odor of the compound of previously described formula (1)
With.
R6~R10Shown alkoxy is saturations or undersaturated straight chain shape or the alkoxy of branched, can be such as carbon
The alkoxy of number 1~20, preferably carbon number 1~10, more preferably carbon number 1~6, can be such as methoxyl group, second specifically
Oxygroup, positive propoxy, isopropoxy, n-butoxy, sec-butoxy, isobutoxy, tert-butoxy, amoxy or hexyloxy etc..
R6~R10Shown alkyl is not particularly limited, and can be such as alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkyl alkane
Base, aryl or aralkyl.
R6~R10Shown aforesaid alkyl can be such as carbon number 1~20, be preferably carbon number 1~10, be more preferably carbon number 1
~6 straight-chain or the alkyl of branched can be methyl, ethyl, n-propyl, isopropyl, sec-butyl or tertiary fourth specifically
Base etc..
R6~R10Shown foregoing alkenyl can be such as carbon number 2~20, be preferably carbon number 2~10, be more preferably carbon number 2
~6 straight-chain or the alkenyl of branched can be vinyl, 1- acrylic, 2- acrylic, isopropenyl, 1- specifically
Cyclobutenyl, 2- cyclobutenyls, 3- cyclobutenyls, 1- methyl-1-propylenes base, 2- methyl-1-propylenes base, 1- methyl -2- acrylic, 2- first
Base -2- acrylic or 1- ethyl-vinyls etc..
Foregoing alkynyl can be such as carbon number 2~20, is preferably carbon number 2~10, be more preferably the straight-chain of carbon number 2~6
Or the alkynyl of branched, can be acetenyl, 1- propinyls, 2-propynyl, 1- butynyls, 2- butynyls, 3- fourths specifically
Alkynyl or 1- methyl -2-propynyl etc..
R6~R10Shown foregoing cycloalkyl can be the cycloalkyl of such as carbon number 3~12, can be ring third specifically
Base, cyclobutyl, cyclopenta, cyclohexyl, suberyl, cyclooctyl or adamantyl etc..
R6~R10Shown foregoing cycloalkyl-alkyl can be included for example by the cycloalkyl of carbon number 3~12 and carbon number 1~20
Alkyl cycloalkyl-alkyl, can be Cvclopropvlmethvl, cyclobutylmethyl, cyclopentyl-methyl or cyclohexyl specifically
Methyl etc..
R6~R10Shown aforesaid aryl can be the aryl of such as carbon number 6~18, can be phenyl, naphthalene specifically
Base, anthryl, phenanthryl or xenyl etc..
R6~R10Shown foregoing aralkyl can be the aralkyl of such as carbon number 7~16, can be benzyl specifically
Base, 1- phenylethyls, 2- phenylethyls, 1- phenyl propyls, 2- phenyl propyls, 3- phenyl propyls or diphenyl methyl etc..
R6~R10Ring can be formed by being selected from arbitrary 2 among them.Foregoing ring can be the yuan of rings of such as 3 yuan of rings~8
Non-aromatic hydrocarbon ring, non-aromatic heterocyclic, aromatic series hydrocarbon ring or heteroaromatic.Foregoing non-aromatic hydrocarbon ring can be for example
Cycloalkanes hydrocarbon ring (cyclopropane ring, cyclobutane ring, pentamethylene ring, cyclohexane ring, cycloheptane ring and cyclooctane ring etc.) or cycloolefin
Ring (cyclopentene ring, cyclohexene ring, cycloheptene ring and cyclo-octene ring etc.) etc..
Foregoing non-aromatic heterocyclic can be such as tetrahydrochysene -2H- pyranoid rings, tetrahydrochysene -2H- thio-pyryliums ring, piperidine ring, two
Oxane ring, thioxane ring, morpholine ring, thiomorpholine ring, dithiane ring, piperazine ring, pyrrolidine ring, thiophane ring,
Tetrahydrofuran ring, 1,3- oxazolidines ring, dithiolane ring, oxathiolane ring or dioxolanes etc..Aforementioned fragrance race hydrocarbon
Ring can be such as phenyl ring.Aforementioned fragrance race heterocycle can be for example furan nucleus, thiphene ring, pyrrole ring, pyridine ring, pyridine ring,
Pyrimidine ring, pyridazine ring, imidazole ring, pyrazole ring, thiazole ring, oxazole ring Huo isoxazole rings etc..
On R6~R10, it is preferred that R6And R9For hydrogen atom, and R7、R8And R10For hydroxyl, alkoxy or alkyl.If
R6~R10For the combination, then the effect of the foreign odor of the compound of previously described formula (1) is sheltered using the compound of previously described formula (2)
It is more excellent.
At least one kind of compound shown in previously described formula (2) be preferably selected from by anisole, veratrole, estragole, guaiacol,
4-ethyl guaiacol, hydroquinone dimethyl ether, anethole, resorcin dimethyl ether, methyl phenol and p-tolyl methyl ether
One or more of group of composition.It is illustrated below go out previously described formula (2) compound represented chemical constitution.
Made using the compound of previously described formula (2) to shelter or reduce the masking of the foreign odor of the compound of previously described formula (1)
With or reduction effect need not be bound to specific theory, it is believed that：Since the characterization of molecules of such as these compounds is total to
The general character, signal multilated that osmoreceptor is sent and given play to above-mentioned effect.It can think：On previously described formula (1)
Compound, each part-structure in chemical constitution are bonded to multiple osmoreceptors, according to the osmoreceptor of its bonding
Species and generate characteristic signal pattern for the bond strength of each osmoreceptor, but the chemical combination of previously described formula (2)
The chemical constitution of object and the offset of charge etc. divide the compound of subcharacter and previously described formula (1) be it is common, therefore, two kinds of compounds
It is competitively mutually bonded with a part of osmoreceptor, the characteristic signal image of previously described formula (1) is disturbed, and therefore, brain can not
The signal pattern is perceived as to the peculiar smell of the compound of previously described formula (1).
The present invention smelly eliminating composition in previously described formula (2) as long as shown at least one kind of compound mass concentration
The effective concentration for having given play to the uncomfortable effect of compound of masking previously described formula (1), is just not particularly limited, can be with
1 times or more for the quality of at least one kind of compound shown in such as previously described formula (1), be preferably more than 10 times, be more preferably 100
Times or more.Specifically, the mass concentration of at least one kind of compound shown in previously described formula (2) can be more than 1ppq, be preferably
More than 1ppt, more preferably more than 0.1ppb.The upper limit value of the mass concentration of at least one kind of compound shown in previously described formula (2) does not have
It is particularly limited to, is, for example, that below 1000ppm or below 10ppm also can effectively play a role.
The compound of previously described formula (2) is included in known essential oil or fragrance, accordingly it is also possible to which previously described formula (2) chemical combination will be included
The essential oil or fragrance of object are used for the smelly eliminating composition of the present invention as the supply source of the compound of previously described formula (2).Foregoing essence
It as long as oil or fragrance include the compound of previously described formula (2), is just not particularly limited, can be that the essential oil of such as fennel (includes wormwood artemisia
Brain), the essential oil of sweet basil (including estragole), the essential oil (including estragole) of tarragon, octagonal essential oil (including anethole), fennel seed
The leaf (including estragole) of (including estragole and anethole), sweet basil, leaf (including estragole), the octagonal fruit of tarragon (include
Anethole), the fruit of vanilla (including guaiacol), the bud (including guaiacol) of cloves or aniseed (include fennel
Brain) etc..In foregoing essential oil or fragrance, in addition to the compound comprising previously described formula (2), also comprising a variety of fragrance ingredients, therefore,
There is significantly high masking effect not only for the foreign odor of the compound of previously described formula (1), additionally it is possible to improve this tremendously
The smelly eliminating effect of the smelly eliminating composition of invention.
Smelly eliminating as the present invention is smelt with the compound of the previously described formula (1) of the deodorizing ingredient included in composition by hindering
Feel the cationic channel of cell and give play to smelly eliminating effect (barrier effect of nerve conduction), therefore, no matter which kind of class peculiar smell is,
Various peculiar smell can be reduced.The smelly eliminating of the present invention can be applied to be not particularly limited with the odorant of composition, it can be exemplified by
As acetaldehyde (irritating green grass peculiar smell), ammonia (dung urine peculiar smell), isopentyl aldehyde (the sour-sweet peculiar smell being charred as asphyxia),
Isobutanol (irritating fermentation peculiar smell), isobutylaldehyde (irritating sour-sweet peculiar smell being charred), the isovaleric acid (socks of sultry humidity
Such peculiar smell), dimethylbenzene (peculiar smell as gasoline), styrene (peculiar smell as city gas), (rotten fish is such for trimethylamine
Peculiar smell), toluene (peculiar smell as gasoline), valeraldehyde (the sour-sweet peculiar smell being charred as asphyxia), n-butanal it is (irritating
The sour-sweet peculiar smell being charred), positive valeric acid (peculiar smell as the socks of sultry humidity), n-butyric acie (stink with perspiration), propionic aldehyde (irritating acid
The peculiar smell that sweet tea is charred), propionic acid (irritating tart flavour), methyl iso-butyl ketone (MIBK) (peculiar smell as irritating diluent), methyl
Mercaptan (peculiar smell as rotten onions), ethyl acetate (peculiar smell as irritating diluent (シ ン ナ ー)), curing
Methyl (curing メ チ Le) (rot peculiar smell as cabbage), methyl sulfide (rot peculiar smell as cabbage), hydrogen sulfide
(peculiar smell as rotten egg), acetic acid, butyric acid, caproic acid (stink with perspiration, body odour), nonenyl aldehyde (body odour of the elderly), scatol (excrement
Just stink) or indoles (stool odor) etc..Like this, smelly eliminating of the invention can be answered with composition for various odorants
With, therefore, can be applied to peculiar smell that clothes, room or automobile etc. distribute, be specially the peculiar smell of cigarette, the peculiar smell of food, body odour,
Body odour plus age peculiar smell, old peculiar smell, lavatory peculiar smell, the peculiar smell of aqueous rubbish, peculiar smell of pet, undried washings peculiar smell,
The peculiar smell of new building or the peculiar smell of new car etc..
The smelly eliminating effect or the effect of reduction peculiar smell realized by the smelly eliminating composition of the present invention can pass through this technology
The method of generally use is evaluated in field.For example, in six stage peculiar smell intensity representations, be divided into as follows 0~5 this
Six stages evaluate the intensity of smell.
0 free from extraneous odour
1 smell that can be perceived reluctantly
2 are difficult to be judged as the smell of which kind of smell
3 smells that can be perceived easily
4 stronger smells
5 strong smells
In addition, in nine stages comfortable immoderation representation, it was divided into for -4~4 this nine stages as follows to evaluate gas
The essence of taste.
- 4 is extreme uncomfortable
- 3 is very uncomfortable
- 2 is uncomfortable
- 1 is slightly uncomfortable
0 is non-comfortable nor uncomfortable
1 is slightly comfortable
2 is comfortable
3 as snug as a bug in a rug
4 is extreme comfortable
In some way, the present invention relates to the deodorants for accommodating foregoing smelly eliminating composition.The deodorant of the present invention
As long as form can give play to smelly eliminating effect, be just not particularly limited, can be for example aerosol type, aerial fog type, fixed or
Person's artificial tooth deodorant etc..The deodorant of the present invention can be applied to the peculiar smell that clothes, room or automobile etc. distribute, be specially cigarette
Peculiar smell, the peculiar smell of food, body odour, body odour plus age peculiar smell, old peculiar smell, lavatory peculiar smell, the peculiar smell of aqueous rubbish, peculiar smell of pet,
Peculiar smell of the peculiar smell of undried washings, the peculiar smell of new building or new car etc..
In some way, the present invention relates to the resins or building materials that include foregoing smelly eliminating composition.By by the present invention
Resin or building materials for manufacture such as furniture, the component (hood (ボ Application ネ ッ ト)) of automobile or apartment etc., can
It reduces in room or the peculiar smell of cigarette in automobile, the peculiar smell of food, body odour, body odour plus age peculiar smell, old age peculiar smell, lavatory is different
Taste, the peculiar smell of aqueous rubbish, peculiar smell of pet, the peculiar smell of undried washings, the peculiar smell of the peculiar smell of new building or new car
Deng.
It to be eaten in some way, the present invention relates to the beverage/food additives comprising foregoing smelly eliminating composition or beverage
Product.By by the beverage/food additive application of the present invention in the stronger food composition of such as peculiar smell or food materials (liver extract,
Docosahexaenoic acid, konjaku silk, dried food and nuts, pickle or alec when) or when being used in edible such food composition or food materials
Seasoning, the peculiar smell of foregoing food composition or food materials can be reduced.In addition, in the beverage/food of the present invention, eaten from the beverage
The food composition or the stronger peculiar smell of food materials used in product is minimized, and can compatibly be eaten.
In some way, the present invention relates to prevented and kill off to use product with the peculiar smell of composition comprising foregoing smelly eliminating.The present invention's
As long as peculiar smell is prevented and kill off can give play to peculiar smell preventive effect with the form of product, be just not particularly limited, can be such as mask,
Nasal drop, ointment or toilet cream (ク リ ー system) etc..By the way that the peculiar smell of the present invention is prevented and kill off the week equipped with product or applied to nose
It encloses or applied to the position as gas with foreign flavor, various peculiar smell can be reduced.
In some way, the present invention relates to the method for reducing object peculiar smell, this method includes：Make aforementioned object or including
The process that foregoing smelly eliminating composition is included in the space of aforementioned object or composition.As aforementioned object, may be employed has
The object of various peculiar smell, for example, can be using clothes, room, automobile, resin, building materials, food composition or food materials etc. as object
Implement the method for the present invention.
In some way, the masking use of the foreign odor the present invention relates at least one kind of compound shown in previously described formula (1)
Composition, said composition include at least one kind of compound shown in previously described formula (2).The masking composition of the present invention can incite somebody to action
At least one kind of compound shown in previously described formula (1) for smelly eliminating and before use, while use or after use, in order to shelter
Or it reduces the foreign odor of at least one kind of compound shown in the formula (1) and uses.
Hereinafter, the present invention is illustrated by embodiment, but the scope of the present invention is not limited to these embodiments.
Embodiment
(embodiment 1)
TCA (Kanto Kagaku K. K.'s system) is dissolved in the water, prepares the aqueous solution of the TCA comprising 1ppm.To the water
Various masking ingredients are added in solution, it is tested and is capable of the fustiness of no masking TCA.Evaluation by smelt by skilled estimator take it is molten
The function of liquid peculiar smell is tested to carry out.As foregoing masking ingredient, anethole (Kanto Kagaku K. K.'s system), estragole have been used
(Kanto Kagaku K. K.'s system), methyl phenol (rice Chinese yam product Industrial Co., Ltd system), veratrole, guaiacol (rice Chinese yam
Product Industrial Co., Ltd system), resorcin dimethyl ether, hydroquinone dimethyl ether (Wako Pure Chemical Industries, Ltd.'s system), ethyl
Guaiacol (Junsei Chemical Co., Ltd.'s system) and p-tolyl methyl ether.Show the result in table 1.
[table 1]
Table 1：For the effect of the masking ingredient of TCA fustiness
×：Feel fustiness strongly.
○：Fustiness is minimized.
◎：Imperceptible fustiness.
Fustiness, but the masking ingredient by coordinating the present invention, the fustiness of TCA are felt by the solution for only including TCA strongly
It is minimized.It should be noted that by guaiacol, resorcin dimethyl ether, hydroquinone dimethyl ether, guaethol or
When person's p-tolyl methyl ether is used as masking ingredient, although the fustiness of TCA is minimized, these masking ingredients are felt strongly certainly
The characteristic peculiar smell of body.
(embodiment 2)
For the peculiar smell comprising TCA and the smelly eliminating composition of estragole, further experiment in detail.Into the water of 80 mass parts
96% ethyl alcohol of 20 mass parts is mixed, and adds TCA and estragole thereto, prepares smelly eliminating composition.By prepared smelly eliminating
It is fitted into composition 0.1cc into commercially available polybag, stands after five minutes, opened the sack by skilled estimator and smelt and take
Peculiar smell.The peculiar smell of fustiness and estragole itself for TCA is evaluated by six stage odor strength representations, for smelly eliminating
With comfortable/immoderation of composition entirety, using nine stages, comfortably uncomfortable representation is evaluated.Show the result in table 2 below.
[table 2]
Table 2：The peculiar smell of smelly eliminating composition comprising TCA and estragole
In the composition that TCA is only included without estragole, the fustiness from TCA is perceived, is evaluated as the gas of extreme discomfort
Taste.On the other hand, if coordinating estragole into the composition comprising TCA, the fustiness from TCA is masked, if improving wormwood artemisia
The concentration of brain, then its masking effect also improve.
(embodiment 3)
For the peculiar smell comprising TCA and the smelly eliminating composition of anethole, further experiment in detail.Except using anethole
It replaces outside estragole, prepares smelly eliminating composition according to the method for embodiment 2, and evaluate its peculiar smell.It shows the result in following
Table 3.
[table 3]
Table 3：The peculiar smell of smelly eliminating composition comprising TCA and anethole
In the composition that TCA is only included without anethole, the fustiness from TCA is perceived, is evaluated as extreme discomfort
Smell.On the other hand, if coordinating anethole into the composition comprising TCA, the fustiness from TCA is masked, if carried
The concentration of high anethole, then its masking effect also improve.
(embodiment 4)
Method according to embodiment 2 prepares the smelly eliminating comprising TCA 100ppb and comprising various masking ingredient 1000bp and uses
Composition, and evaluate its peculiar smell.As control, limonene (the key aroma ingredient of lemon) and 1,8- cineole (fan have been used
Repeatedly fragrant key aroma ingredient).Show the result in table 4 below.
[table 4]
Table 4：The peculiar smell of smelly eliminating composition comprising TCA and various masking ingredients
If combining the compound for coordinating previously described formula (2) with TCA, the fustiness from TCA is masked.On the other hand,
Fragrance ingredient without chemical constitution shown in previously described formula (2) can not shelter the fustiness from TCA.
(embodiment 5)
It is tested for the smelly eliminating comprising TBA and estragole with the peculiar smell of composition.Except using TBA (the pure medicine industry of woods
Co. Ltd. system) it replaces outside TCA, smelly eliminating composition is prepared according to the method for embodiment 2, and evaluates its peculiar smell.It will knot
Fruit is shown in table 5 below.
[table 5]
Table 5：The peculiar smell of smelly eliminating composition comprising TBA and estragole
In the composition that TBA is only included without estragole, the fustiness from TBA is perceived, is evaluated as the gas of extreme discomfort
Taste.On the other hand, if coordinating estragole into the composition comprising TBA, the fustiness from TBA is masked.As can be seen：
The compound of previously described formula (2) not only shelters the peculiar smell from TCA, is also played for being derived from the peculiar smell of compound of previously described formula (1)
Go out masking effect.
(embodiment 6)
It is tested for the smelly eliminating of the present invention with the smelly eliminating effect of composition.
Various odorants are added in water, prepare stench composition).In addition, 20 matter are mixed into the water of 80 mass parts
96% ethyl alcohol of part is measured, and adds TCA and estragole thereto, prepares smelly eliminating composition.By prepared stench composition) 1cc
It is fitted into commercially available polybag, stands after five minutes, prepared smelly eliminating with composition 1cc is packed into and is combined comprising foregoing stench
In the polybag of object, 5 minutes are stood.
Thereafter, opened the sack by skilled estimator and smelt and take peculiar smell.For comfortable/immoderation of peculiar smell, nine are utilized
Stage, comfortably uncomfortable representation was evaluated.Show the result in following tables 6.
[table 6]
Table 6：The smelly eliminating effect of smelly eliminating composition comprising TCA and estragole
The smelly eliminating of the present invention reduces the peculiar smell of various odorants with composition, does not also have the fustiness from TCA, therefore
Excellent smelly eliminating effect is given play to.On the other hand, only in the composition comprising TCA, the peculiar smell of odorant is minimized, but mould
Smelly relatively strong, as discomfort peculiar smell.In addition, not having for masking ingredient, the i.e. estragole of TCA fustiness reduces the different of odorant
The effect of taste.
(embodiment 7)
(1) example of aerosol type deodorant
Trichloroanisole (TCA), estragole, second alcohol and water are mixed with the ratio shown in table 7 below, preparation includes
The smelly eliminating composition of TCA 1ppb, estragole 10ppm and 19.2 mass % of ethyl alcohol.The smelly eliminating is accommodated with composition to spraying and is held
In device, aerosol type deodorant is manufactured.The aerosol type deodorant shows excellent smelly eliminating effect, but hardly feels and be derived from
The fustiness of TCA.
[table 7]
Table 7：The composition example of smelly eliminating composition
(2) example of aerosol type strength deodorant
Trichloroanisole (TCA), estragole, second alcohol and water are mixed with the ratio shown in table 8 below, preparation includes
The smelly eliminating composition of 19.2 mass % of TCA 10ppb, 0.1 mass % of estragole and ethyl alcohol.By the smelly eliminating with composition accommodate to
In automiser spray, aerosol type strength deodorant is manufactured.The aerosol type strength deodorant shows the aerosol type smelly eliminating than above-mentioned (1)
The stronger smelly eliminating effect of agent, but hardly feel the fustiness from TCA.
[table 8]
Table 8：The composition example of smelly eliminating composition
As can seen above：The foreign odor of the compound of previously described formula (1) can be sheltered or reduced to the compound of previously described formula (2), and
And compound comprising previously described formula (1) and the smelly eliminating of the compound of previously described formula (2) have given play to various odorants with composition
Smelly eliminating effect.Therefore, deodorant of smelly eliminating effect for the compound for applying previously described formula (1) etc. can be developed.
Claims (14)
1. a kind of smelly eliminating composition, it includes：Shown at least one kind of compound and following formula (2) shown in following formula (1)
At least one kind of compound,
In formula (1), R1~R5It is same or different to each other, represents hydrogen atom, halogen atom or the alkyl optionally with substituent group,
R1~R5In at least one be halogen atom；
In formula (2), R6~R10It is same or different to each other, represents hydrogen atom, hydroxyl, alkoxy or alkyl.
2. smelly eliminating composition according to claim 1, wherein, at least one kind of compound shown in the formula (1) is 2,4,
6- Trichloroanisoles and/or 2,4,6- tribromo anisoles.
3. smelly eliminating composition according to claim 1 or 2, wherein, in the formula (2), R6And R9For hydrogen atom, R7、R8
And R10For hydroxyl, alkoxy or alkyl.
4. smelly eliminating composition described in any one of claim 1 to 3, wherein, it is at least one kind of shown in the formula (2)
Compound is selected from by anisole, veratrole, estragole, guaiacol, 4-ethyl guaiacol, hydroquinone dimethyl ether, fennel
One or more of group that brain, resorcin dimethyl ether, methyl phenol and p-tolyl methyl ether form.
5. smelly eliminating composition according to any one of claims 1 to 4, wherein, it is at least one kind of shown in the formula (2)
The content of compound is 1 times or more of the content of at least one kind of compound shown in the formula (1).
6. according to smelly eliminating composition according to any one of claims 1 to 5, wherein, it is at least one kind of shown in the formula (1)
The mass concentration of compound is more than 1ppq.
7. a kind of deodorant accommodates smelly eliminating composition according to any one of claims 1 to 6.
8. a kind of resin or building materials, it includes smelly eliminating compositions according to any one of claims 1 to 6.
9. a kind of beverage/food additive or beverage/food, it includes smelly eliminating according to any one of claims 1 to 6 combinations
Object.
10. a kind of peculiar smell is prevented and kill off with product, it includes smelly eliminating compositions according to any one of claims 1 to 6.
A kind of 11. method for reducing object peculiar smell, which is characterized in that it includes：Make the object or include the sky of the object
Between or composition in contain smelly eliminating composition according to any one of claims 1 to 6 process.
12. a kind of masking composition, which is characterized in that it is at least one kind of compound for sheltering shown in following formula (1)
The composition of foreign odor,
It includes at least one kind of compound shown in following formula (2),
In formula (1), R1~R5It is same or different to each other, represents hydrogen atom, halogen atom or the alkyl optionally with substituent group,
R1~R5In at least one be halogen atom；
In formula (2), R6~R10It is same or different to each other, represents hydrogen atom, hydroxyl, alkoxy or alkyl.
13. the masking composition described in smelly eliminating composition according to any one of claims 1 to 6 or claim 12 exists
Manufacture deodorant, resin, building materials, beverage/food additive, beverage/food or peculiar smell are prevented and kill off with the application in product.
14. masking composition described in claim 12 for sheltering or reduce formula defined in claim 12 (1) institute
The application of the foreign odor at least one kind of compound shown.
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| JP2016218826A JP6371817B2 (en) | 2016-11-09 | 2016-11-09 | Deodorant composition or masking composition and methods of use thereof |
| JP2016-218826 | 2016-11-09 |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1863653A (en) * | 2003-08-07 | 2006-11-15 | 电离卫生产品芯片中心有限公司 | Process for eliminating/reducing compounds with a musty taste/odour in materials that are to come into contact with foodstuffs and in foods or drinks |
| JP2013147475A (en) * | 2012-01-23 | 2013-08-01 | Osaka Univ | Cation channel inhibitor and olfactory desensitizer composition including the same |
| US20150110669A1 (en) * | 2013-10-22 | 2015-04-23 | Kao Corporation | Inhibitor of Odor Caused by Sotolone |
| JP2015211667A (en) * | 2014-04-14 | 2015-11-26 | 花王株式会社 | Search method of urine odor suppressor |
| CN105339509A (en) * | 2013-06-29 | 2016-02-17 | 弗门尼舍有限公司 | Methods of identifying, isolating and using odorant and aroma receptors |
| JP5982044B2 (en) * | 2015-07-09 | 2016-08-31 | 花王株式会社 | Odor control agent |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4755503A (en) * | 1987-10-21 | 1988-07-05 | Givaudan Corporation | Fragrance compositions containing 2,4,6-tribromo-3-methylanisole methylanisole |
-
2016
- 2016-11-09 JP JP2016218826A patent/JP6371817B2/en active Active
-
2017
- 2017-11-08 CN CN201711090588.4A patent/CN108057125A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1863653A (en) * | 2003-08-07 | 2006-11-15 | 电离卫生产品芯片中心有限公司 | Process for eliminating/reducing compounds with a musty taste/odour in materials that are to come into contact with foodstuffs and in foods or drinks |
| JP2013147475A (en) * | 2012-01-23 | 2013-08-01 | Osaka Univ | Cation channel inhibitor and olfactory desensitizer composition including the same |
| CN105339509A (en) * | 2013-06-29 | 2016-02-17 | 弗门尼舍有限公司 | Methods of identifying, isolating and using odorant and aroma receptors |
| US20150110669A1 (en) * | 2013-10-22 | 2015-04-23 | Kao Corporation | Inhibitor of Odor Caused by Sotolone |
| JP2015211667A (en) * | 2014-04-14 | 2015-11-26 | 花王株式会社 | Search method of urine odor suppressor |
| JP5982044B2 (en) * | 2015-07-09 | 2016-08-31 | 花王株式会社 | Odor control agent |
Non-Patent Citations (1)
| Title |
|---|
| TAKAHASHI YK等: "Topographic Representation of Odorant Molecular Features in the Rat", 《JOURNAL OF NEUROPHYSIOLOGY》 * |
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| JP2018075172A (en) | 2018-05-17 |
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