CN108056931A - 一种祛痘霜及其制备方法 - Google Patents
一种祛痘霜及其制备方法 Download PDFInfo
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Abstract
本发明属于化妆品领域,具体涉及一种祛痘霜及其制备方法。所述祛痘霜中伞花烃‑5‑醇和己脒定或己脒定二(羟乙基磺酸)盐是杀菌消炎、祛痘的主要成分,泰葛美汀、丹皮酚可以配合增强祛痘效果,丹皮酚能促进面部皮肤血液循环,活化衰老的表皮细胞,能使皮肤白嫩,防老,对青春痘效果尤佳;泰葛美汀通过阻滞H2受体而发挥显著的抑制过敏的作用,并有效减轻瘙痒症状,配以合适比例的其他原料如抗过敏剂、增稠剂、乳化剂、保湿剂、皮肤调理剂、润肤剂、渗透剂、镇痛剂、抗过敏剂、防腐剂和赋香剂等,最终制得的祛痘霜配方合理,使用方便,祛痘效果好,愈合修复快,在祛痘的同时能够促进皮肤创口的修复。
Description
技术领域
本发明属于化妆品领域,具体涉及一种祛痘霜及其制备方法。
背景技术
痘痘、粉刺好发于青少年,对青少年的心理和社交影响很大,但青春期后往往能自然减轻或痊愈。痤疮的发生主要与皮脂分泌过多、毛囊皮脂腺导管堵塞、细菌感染和炎症反应等因素密切相关。进入青春期后人体内雄激素特别是翠酮的水平迅速升高,促进皮脂腺发育并产生大量皮脂,同时毛囊皮脂腺导管的角化异常造成导管堵塞,皮脂排出障碍,形成角质栓即微粉刺。痘痘、粉刺必然有皮肤伤口,导致炎症或受到细菌感染等原因会造成皮肤创口持久,影响人们的外表和生活交流,一些市面上的祛痘产品见效慢,痘痘祛除后会留下痘印,更有些去痘痘的产品会使得痘痘加重或使皮肤易产生过敏性红疹,而一些祛除痘的产品在祛除好停止使用后皮肤表面可能会再一次出现出痘痘的症状。
发明内容
为解决现有技术的缺点和不足之处,本发明的首要目的在于提供一种祛痘霜,其配方合理,使用方便,祛痘效果好,愈合修复快。
本发明的另一目的在于提供上述去祛痘霜的制备方法。
本发明的目的通过下述技术方案实现:
一种祛痘霜,包括A组、B组、C组和D组原料,具体原料种类及质量比例如下:
上述各原料质量百分比总和为100%。
优选的,所述祛痘霜具体原料种类及质量比例如下:
上述祛痘霜的制备方法,包括以下步骤:
(1)使A组原料在75~80℃下溶解,再加入B组原料,维持温度不变,搅拌混合,乳化均质;
(2)使C组原料在45~55℃下溶解,再加入到步骤(1)得到的A和B组混合物中,在45~55℃下混合搅拌均匀;
(3)将D组原料加入步骤(2)得到的A、B、C组混合物中,在40~50℃下搅拌溶解均匀,然后保持混合物在0~45℃,搅拌后得到所述祛痘霜。
优选的,步骤(1)中乳化均质1~6分钟,静置30分钟后降温至45~55℃。
在上述祛痘霜中,各组分的具体作用如下:
水,丙二醇,PEG-400分别作为溶剂和助溶剂,促使各种成分充分溶解,容易发挥作用;
PEG-100甘油酯硬脂酸作为乳化剂可以促使油在水中均匀分散,并能够形成稳定的体系,但乳化剂不限于上述选择;
卡波姆和三乙醇胺起稳定增稠作用,使祛痘霜更稳定,但增稠剂不限于上述选择;
甜菜碱,学名为三甲基甘氨酸,具有强烈的吸湿性能,保湿性强,保持皮肤水分水分,起到皮肤作用,但保湿剂不限于上述选择;
烟酰胺(VB3),体内缺乏烟酰胺时会得糙皮病,可预防糙皮病,在蛋白质和糖的新陈代谢中起作用,可改善皮肤炎症;
尿素能溶解角蛋白,从而使角质软化和溶解,增强有效成分渗入表皮细胞,发挥药物作用;
烟酰胺和尿素在祛痘霜中可作为皮肤调理剂使用,但皮肤调理剂不限于上述选择;
生育酚即维生素E(Ve),增加细胞的抗氧化作用,维持和促进生殖机能,具有一定的抗老化作用,还能改善脂质代谢,防止动脉硬化,降低血脂,增强身体免疫功能;
橄榄油,富含与皮肤亲和力极佳的角鲨烯,能被人体迅速吸收,保持皮肤弹性和润泽,所含丰富的单不饱和脂肪酸和维生素E、K、A、D等及酚类抗氧化物质,能消除面部皱纹,防止肌肤衰老,有护肤护发和防治手足皴裂等功效;
大豆异黄酮,是黄酮类化合物,其作用包括:a、抑制酶和增长因子作用;b、弱雌激素和抗雌激素作用,减少雄性皮肤痘痘因素;c、大豆异黄酮对动物有比较明确的抗氧化作用,能够提高皮肤细胞免疫活性;d、研究发现,其在体外抑制内皮细胞增生和血管生成作用较强,促进皮肤正常代谢;e、大豆异黄酮从大豆植物中提取,与雌激素有相似结构,又称植物雌激素。它的雌激素作用影响到激素分泌、代谢生物学活性、蛋白质合成、生长因子活性,提高皮肤细胞免疫机能,平衡雄性激素,调节皮肤脂肪分泌,减少皮下脂肪堆积。
生育酚、橄榄油和大豆异黄酮在祛痘霜中可共同作为润肤剂使用,但润肤剂不限于上述选择;
尿囊素具有促进细胞生长,加快伤口愈合,软化角质蛋白等生理功能,用于缓解和治疗皮肤干燥症、鳞屑性肤疾患、皮肤溃疡,对痤疮青春痘有较好疗效;同时具有止痛、抗氧化作用,能使皮肤保持水份,滋润和柔软;
甘草酸二钾有抗炎、抗过敏、保湿等功效,可以中和或减低化妆品的有毒物质,也可以防止有的化妆品的过敏反应,可防止皮肤炎、皮肤干燥、日晒、皮疹等;
尿囊素和甘草酸二钾在祛痘霜中可作为抗过敏剂使用,但抗过敏剂不限于上述选择。
冰片和薄荷脑能刺激神经末梢的冷感受器而产生冷感,造成深部组织血管的变化而起到消炎、止痛、止痒,清热散毒,散火解毒等作用,在祛痘霜中可作为镇痛剂使用,但镇痛剂不限于上述选择。
伞花烃-5-醇和己脒定或己脒定二(羟乙基磺酸)盐是杀菌消炎、祛痘的主要成分,伞花烃-5-醇具有广普杀菌性,对各种细菌,酵母菌,真菌,病毒等均有作用。己脒定或己脒定二(羟乙基磺酸)盐是具有广谱抗菌和杀菌性能的阳离子性物质,对各种革兰氏阳性菌及阴性菌以及各种霉菌和酵母菌都有很高的的杀菌和抑菌性能,消除痘痘,痤疮引发的病原微生物炎症反应;
泰葛美汀、丹皮酚可以配合增强祛痘效果,丹皮酚能促进面部皮肤血液循环,活化衰老的表皮细胞,能使皮肤白嫩,防老,对青春痘效果尤佳。泰葛美汀,用于祛痘、除粉刺产品,通过阻滞H2受体而发挥显著的抑制过敏的作用,并有效减轻瘙痒症状;
苯氧乙醇,为温和防腐剂,具有一定的杀菌消炎作用,但防腐剂不限于上述选择;赋香剂为满足消费者的个人爱好设计的,清新好闻的香味能更加吸引消费者。
总体来说,通过保湿剂的保湿、润肤剂和维生素的润肤和营养、增强细胞的免疫性;皮肤调理剂及软化剂的软化角质,促进细胞再生和创口愈合;杀菌剂的杀菌作用;消炎剂、抗过敏剂的减少炎症反应;渗透剂的促进药物渗透增强药效;乳化剂和增稠剂的稳定祛痘霜体系作用;其中伞花烃-5-醇,己脒定或己脒定二(羟乙基磺酸)盐,泰葛美汀、丹皮酚是本品祛痘霜主要有效成分,起关键性的作用,其它成分为辅助作用,整体配合作用达到综合的比较完美的祛痘效果。这也是本发明产品相对于现有技术的特点和优点。
具体实施方式
下面结合实施例对本发明作进一步详细的描述,但本发明的实施方式不限于此。
表1 三种配方的原料组成及比例
上述三种配方的制备方法如下:
(1)使A组原料在76℃下溶解,再加入B组原料,维持温度不变,搅拌混合,乳化均质4分钟,维持温度不变静置30分钟后,然后降温至50℃。
(2)使C组原料在50℃下溶解,再加入到步骤(1)得到的A和B组混合物中,在50℃下混合搅拌均匀;
(3)将D组原料加入步骤(2)得到的A、B、C组混合物中,在45℃下搅拌溶解均匀,然后保持混合物在45℃以下,搅拌均匀后得到所述祛痘霜。
表2 三种配方得到的祛痘霜的效果
表2归纳了三种配方的效果,其中受测人群30%为男性,70%为女性,年龄介于16~35岁,受测者每日使用祛痘霜2次,早晚各一次,7天为一个疗程。
上述实施例为本发明较佳的实施方式,但本发明的实施方式并不受上述实施例的限制,其他的任何未背离本发明的精神实质与原理下所作的改变、修饰、替代、组合、简化,均应为等效的置换方式,都包含在本发明的保护范围之内。
Claims (7)
1.一种祛痘霜,其特征在于,包括A组、B组、C组和D组原料,其中A组原料包括水75-95wt%、抗过敏剂0.05-0.3wt%、增稠剂0.1-0.5wt%、乳化剂0.2-2.0wt%、保湿剂0-2.0wt%和皮肤调理剂0.3-7.0wt%,B组原料包括润肤剂0.3-7.0wt%和渗透剂0.1-1.0wt%,C组原料包括伞花烃-5-醇0.05-0.2wt%、己脒定或己脒定二(羟乙基磺酸)盐0.05-0.2wt%、镇痛剂0.02-0.6wt%、聚乙二醇1.0-10wt%和保湿剂1.0-10wt%,D组原料抗过敏剂0.05-0.5wt%、泰葛美汀0.1-1.0wt%、丹皮酚0.1-1.0wt%、增稠剂0.1-0.5wt%、防腐剂适量和赋香剂适量;
上述各原料质量百分比之和为100wt%。
2.根据权利要求1所述的祛痘霜,其特征在于,所述A组原料中,抗过敏剂为尿囊素,增稠剂为卡波姆,乳化剂为PEG-100甘油酯硬脂酸,保湿剂为甜菜碱,皮肤调理剂为尿素和烟酰胺,用量分别为尿素0.2-5.0wt%和烟酰胺0.1-2.0wt%。
3.根据权利要求1所述的祛痘霜,其特征在于,所述B组原料中,润肤剂为橄榄油、生育酚和大豆异黄酮,用量分别为橄榄油0.1-5.0wt%、生育酚0.1-1.0wt%和大豆异黄酮0.1-1.0wt%。
4.根据权利要求1所述的祛痘霜,其特征在于,所述C组原料中,镇痛剂为冰片和薄荷脑,用量分别为冰片0.01-0.4wt%和薄荷脑0.01-0.2wt%。
5.根据权利要求1所述的祛痘霜,其特征在于,所述D组原料中,抗过敏剂为甘草酸二钾,增稠剂为三乙醇胺,防腐剂为苯氧乙醇,赋香剂为香精。
6.一种权利要求1~5所述祛痘霜的制备方法,其特征在于,包括以下步骤:
(1)使A组原料在75~80℃下溶解,再加入B组原料,维持温度不变,搅拌混合,乳化均质;
(2)使C组原料在45~55℃下溶解,再加入到步骤(1)得到的A和B组混合物中,在45~55℃下混合搅拌均匀;
(3)将D组原料加入步骤(2)得到的A、B、C组混合物中,在40~50℃下搅拌溶解均匀,然后保持混合物在0~45℃,搅拌均匀后得到所述祛痘霜。
7.根据权利要求6所述祛痘霜的制备方法,其特征在于,步骤(1)中乳化均质1~6分钟,静置30分钟后降温至45~55℃。
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CN111281811A (zh) * | 2020-03-20 | 2020-06-16 | 高密丽美生物科技有限公司 | 一种免洗消毒护肤乳霜及其制备方法 |
CN111329817A (zh) * | 2018-12-19 | 2020-06-26 | 曾宪华 | 一种外用高效祛痘药妆配方与制备方法 |
CN114948805A (zh) * | 2021-02-23 | 2022-08-30 | 上海昆药生物科技有限公司 | 一种含有青蒿挥发油的抑菌组合物及其在祛痘护肤品中的应用 |
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