CN1080529A - The manufacture method of dysentery medicine (Salibao) - Google Patents
The manufacture method of dysentery medicine (Salibao) Download PDFInfo
- Publication number
- CN1080529A CN1080529A CN 92106266 CN92106266A CN1080529A CN 1080529 A CN1080529 A CN 1080529A CN 92106266 CN92106266 CN 92106266 CN 92106266 A CN92106266 A CN 92106266A CN 1080529 A CN1080529 A CN 1080529A
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- CN
- China
- Prior art keywords
- rifampicin
- adjuvant
- salibao
- manufacture method
- medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention provides a kind of production veterinary drug---the manufacture method of dysentery medicine (Salibao), its prescription is: rifampicin, bismuth subnitrate and adjuvant; Process is: (1) dry, pulverize, sieve, and mix main materials and auxiliary materials in proportion (2), and (3) start mixer, fully mix in mixer, and incorporation time is not less than 30 minutes, (4) packing.Owing to also there is not a kind of specific drug that can treat the poultry infectious intestinal disease at present, therefore the medicine made from the present invention has been filled up this blank, and it can effectively suppress the intestinal disease of poultry, promotes the development of beastly fowl industry.
Description
The present invention relates to a kind of production method of veterinary drug, particularly treat the production method of the veterinary drug of poultry intestinal disease.
Hakuri and enteritis are the main infectious intestinal disease of poultry, and its pathogen is Salmonella, staphylococcus aureus etc.Above-mentioned disease propagation is strong, and the case fatality rate height already develops for beastly fowl to bring with social economy to have a strong impact on.Still there is not at present a kind of this sick veterinary drug for the treatment of.
The manufacture method that the purpose of this invention is to provide a kind of veterinary drug-dysentery medicine (Salibao), this veterinary drug can be treated the infectious intestinal disease of poultry.
Technical scheme of the present invention is:
1, the prescription of dysentery medicine (Salibao)
Rifampicin: bismuth subnitrate: adjuvant=1: 1.3-1.4: 6.5-6.6
2, foundation
Rifampicin is a broad ectrum antibiotic, and Gram-positive and negative bacterium are had stronger inhibition and bactericidal action, and parasites such as protozoon are also had certain lethal effect, and for example the MIC to golden yellow Fructus Vitis viniferae ball is 0.005 μ g/ml, and escherichia coli MIC is 2.5 μ g/ml; Bismuth subnitrate is widely used convergence medicine clinically, has the protection intestinal mucosa and avoids acids and stimulate, and makes enterokinesia miopragia and reaches anti-diarrhea effect, and have no side effect.
So rifampicin is cooperated the composition compound preparation in the proper ratio with bismuth subnitrate, make it to become existing antibacterial action, the treatment of astriction is arranged again and prevent the efficient medicine of enteritis, dysentery, it is possible that this medicine is used for beastly fowl.
3, technical process
(1), with adjuvant drying, pulverizing, cross 80 mesh sieves, weighing is standby;
(2), get rifampicin and bismuth subnitrate in proportion;
(3), start mixer, as ready become a full member normal after, with rifampicin, bismuth subnitrate and adjuvant with doubly measuring increase method mixing in mixer;
(4), incorporation time was greater than 30 minutes;
(5), packing.
Owing to also there is not a kind of specific drug for the treatment of the poultry infectious intestinal disease at present, therefore the medicine made from the present invention has been filled up this blank, has promoted the development of beastly fowl industry.
Provide an embodiment below.
1, prescription: rifampicin 112.5g
Bismuth subnitrate 150.0g
Glucose 737.5g
2, technical process
(1), with glucose drying, pulverizing, cross 80 mesh sieves;
(2), take by weighing rifampicin and bismuth subnitrate;
(3), start mixer, as ready become a full member normal after, rifampicin, bismuth subnitrate and glucose with doubly measuring the increase method, are mixed in mixer, incorporation time is 45 minutes, makes dysentery medicine (Salibao);
(4), packing, dysentery medicine (Salibao) is packed in the 10g plastic-aluminum pocket.
3, technological requirement
(1), supplementary material all should pass through 80 mesh sieves;
(2), supplementary material forbids to contact starch bowl;
(3), content uniformity is pressed powder, powder is stipulated less than ± 3%.
In adjuvant, also available calcium carbonate replaces glucose.
Claims (2)
1, a kind of manufacture method of veterinary drug-dysentery medicine (Salibao) is characterized in that:
(1), prescription rifampicin: bismuth subnitrate: adjuvant=1: 1.3-1.4: 6.5-6.6
(2), technical process
A, with adjuvant drying, pulverizing, cross 80 mesh sieves, weighing is standby;
B, get rifampicin and bismuth subnitrate in proportion;
C, start mixer, as ready become a full member normal after, with rifampicin, bismuth subnitrate and adjuvant with doubly measuring increase method mixing in mixer;
D, incorporation time were greater than 30 minutes.
2, manufacture method according to claim 1 is characterized in that: described adjuvant is glucose or calcium carbonate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 92106266 CN1080529A (en) | 1992-06-23 | 1992-06-23 | The manufacture method of dysentery medicine (Salibao) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 92106266 CN1080529A (en) | 1992-06-23 | 1992-06-23 | The manufacture method of dysentery medicine (Salibao) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1080529A true CN1080529A (en) | 1994-01-12 |
Family
ID=4941957
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 92106266 Pending CN1080529A (en) | 1992-06-23 | 1992-06-23 | The manufacture method of dysentery medicine (Salibao) |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1080529A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2292884A (en) * | 1994-09-12 | 1996-03-13 | Orion Yhtymae Oy | Rifamycin & bismuth salts for treating bacterial infections |
| GB2293323A (en) * | 1994-09-12 | 1996-03-27 | Orion Yhtymae Oy | Antibiotics and bismuth salts for treating bacterial infections |
-
1992
- 1992-06-23 CN CN 92106266 patent/CN1080529A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2292884A (en) * | 1994-09-12 | 1996-03-13 | Orion Yhtymae Oy | Rifamycin & bismuth salts for treating bacterial infections |
| GB2293323A (en) * | 1994-09-12 | 1996-03-27 | Orion Yhtymae Oy | Antibiotics and bismuth salts for treating bacterial infections |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |