CN108048562A - A kind of DNA chip of the SNPs of noncoding region in the range of European crowd's full-length genome - Google Patents
A kind of DNA chip of the SNPs of noncoding region in the range of European crowd's full-length genome Download PDFInfo
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Abstract
The invention discloses a kind of DNA chip of the SNPs of the noncoding region in the range of European crowd's full-length genome, the DNA chips of the SNPs in particularly a kind of long-chain Noncoding gene region in the range of European crowd's full-length genome.The DNA chip of the SNPs of noncoding region provided by the invention in the range of European crowd's full-length genome, is the DNA chip for being fixed with specific probe；The specific probe is for detecting the probe of 592 SNP in table 1 (information of 592 SNP is shown in Table 1 first row and secondary series).The present invention has great application value for the SNP site detection in mankind's long-chain Noncoding gene region, and the risk assessment and personalized treatment for genetic disease have great application prospect.
Description
Technical field
The present invention relates to molecular biology, functional genomics, bioinformatics and molecular diagnosis fields, are more particularly to
A kind of DNA chip of the SNPs of noncoding region in the range of European crowd's full-length genome.
Background technology
Although human genome has been completed to be sequenced, it is still unknown to lie in substantial amounts of function element therein.Root
Plan the data of newest announcement according to ENCODE, the region of human genome 74.7% can transcribe, and the gene of coding protein
Exon 1 only account for the 2.94% of human genome.Most of protein coding gene is reflected on human genome
Determine and annotate, this, which is just implied on human genome, also has substantial amounts of Noncoding gene up for finding.
When human genome sketch is just issued, just there is sequence design tiling of the researcher according to human genome
Array (covering a watt chip) has the region of transcriptional activity to detect on genome, sent out in No. 21 of the mankind and No. 22 chromosomes
The still unknown gene region of product can largely be transcribed by having showed.The another kind side of long-chain Noncoding gene is found in the genome
Method is by the modification in chromatin on histone.Guttman et al. has found about 5000 K4- on the genome of mouse
K36 regions, what these regional transcriptions came out is all long-chain non-coding RNA, since these regions are all located at protein coding gene
Intergenic region, therefore the long-chain non-coding RNA for transcribing out is referred to as lincRNA (large intergenic noncoding
RNAs).Later Khalil et al. has obtained similar result on the genome of people.Guttman in 2010 et al. utilizes RNA-
Seq technologies are found that substantial amounts of long-chain non-coding RNA in mouse, and it was found that these long-chain non-coding RNAs have similar to egg
More exon genes structures of white matter encoding gene.At subsequent 1 year, Cabili et al. with same method people cell
8000 a plurality of long-chain non-coding RNAs of middle discovery, and incorporate a variety of data and the feature of these long-chain non-coding RNAs is carried out
It portrays.The method of GENCODE plan utilizations RNA-seq is found that the non-volume of substantial amounts of long-chain in different tissues and cell
Code RNA, the annotation of long-chain non-coding RNA is issued since the 7th edition, has up to the present been updated to the 23rd edition, is issued altogether
27817 long-chain non-coding RNA sequences.NONCODE databases are the earliest databases for collecting non-coding RNA sequence, at present
It is updated over to fourth edition, is the most authoritative database of non-coding field.Since the third edition, NONCODE databases start to collect
Long-chain non-coding RNA sequence.
Single nucleotide polymorphism (SNP) is a kind of genome mutation mode being widely present.SNP refers in some crowd
In normal individual, there is a situation where different bases on the single base pair position of genomic DNA.Occur in SNP site
In base, the minimum referred to as minimum equipotential of occurrence number, frequency is known as minimum allelic frequency (MAF).It has been generally acknowledged that SNP's goes out
It is now as caused by the mutation of genomic DNA.The genomic DNA of people has 3,000,000,000 base-pairs, occurs twice in same position
The possibility being even mutated three times is extremely low, and therefore, SNP site is usually all two condition (there are two equipotential).In human genome DNA
Average every 67 bases just have 1 SNP site.But these SNP sites are not to be uniformly distributed in the genome, encoding proteins
Other regions of the SNP site density ratio of the exon 1 of matter are low.According to position in genome, SNP can be divided into gene coding region
SNP, gene noncoding region SNP and intergenic region SNP.The SNP site of protein coding region is divided into as two types：It is synonymous and non-
It is synonymous.Due to the degenerate of codon, synonymous SNP does not change protein sequence, and non-synonymous SNP can change protein sequence
Row.Non-synonymous SNP is divided into as missense and nonsense.Although the SNP in protein coding region will not change the sequence of protein,
It is the expression that possible influence gene in other way, such as transcription factor may be influenced positioned at the SNP site of promoter region
Combination, so as to influence the transcription of gene.
SNP is the third generation molecular labeling after first generation molecular labeling RFLP, second generation molecular labeling microsatellite, generally
For the molecular marking technique based on DNA chip technology.HapMap plans to be found that with thousand human genome plans SNP substantial amounts of
Point and representative tagSNP sites in specific monomer type.Up to the present, dbSNP databases have included people's
More than 5000 ten thousand SNP sites having confirmed.The principle of molecular marking technique based on DNA chip technology is first in full genome
The oligonucleotide probe special to tagSNP sites design equipotential, is fixed on chip, the DNA that then will be detected in the range of group
Sample and chip hybridization, then the genotype for obtaining SNP site is scanned to chip.Molecular labeling based on DNA chip technology
The most important application of technology is whole-genome association (Genome-wide Association Studies, GWASs),
The common research strategies of GWAS are：Case-control strategy, be exactly by comparing with disease crowd (case) and normally
The hereditary variation of crowd (control) finds the susceptibility loci of disease.It can be from everyone DNA sample by SNP chip
Obtain the genotype of Genetic Variations up to a million.What if a type of variation (allele) occurred in patient
Compare frequently, then this SNP is then referred to as related to such disease.These are with the relevant SNPs of disease marking people's gene
The region of disease occurrence risk may be influenced in group.Method with only testing to the hereditary variation of one or more gene regions
It compares, the object of GWAS researchs is whole gene group.Therefore, different from the research for specific gene group region, GWAS is directed to
Whole gene group need not select candidate gene group region in advance.GWAS it can be found that in the relevant susceptibility loci of disease
SNPs and other variations, but specific Disease-causing gene cannot be only determined with correlation.
Affymetrix companies of the U.S. are genetic chip industry forerunners, and world head Zhang Ji were just had developed early in 1989
Because of chip.Its oligonucleotides original position photoetching synthesis patented technology (light-controlled in situ developed
Synthesis of DNA microarrays), be current most high-density chip technology of preparing.Affymetrix
The hardware platform of GeneChip chip systems is by supermatic fluid operating station, high-throughput chip scanner and related spy
The compositions such as pin sequence description and annotations database.Supermatic processing reduces the time hand-manipulated, improves Data duplication
Property.Affymetrix chips, can be every using photoetching technique in situ and stringent Row control synthesis high-density gene chip
Probe of the synthesis more than 4,000,000 on square cm of substrate.Affymetrix chips use unique PM-MM probe design methods,
A pair of 25-mer probes are designed for every section of reference sequences, one of them is to exactly match (perfect match, PM) spy
Pin, the other is wrong site matching (mismatch, MM) probe among sequence.By each pair PM-MM probes during detection
Detection signal synthesis get up, so contribute to distinguish specific binding and the target segment of non-specific binding, be visited so as to improve
Pin sensitivity and specificity.This PM-MM designs are in the detection of low abundance expression product in complex sequence Background Samples
It has a clear superiority.Meanwhile SNP is detected using multiple probes, it effectively reduces probe and hybridizes non-specific influence, and pass through
Suitable algorithm obtains more strong data.
The content of the invention
The object of the present invention is to provide a kind of DNA of the SNPs of the noncoding region in the range of European crowd's full-length genome
Chip, the DNA chip of the SNPs in particularly a kind of long-chain Noncoding gene region in the range of European crowd's full-length genome.
The DNA chip of the SNPs of noncoding region provided by the invention in the range of European crowd's full-length genome, is solid
Surely there is the DNA chip of specific probe；The specific probe is for detecting the probe (letter of 592 SNP of 592 SNP in table 1
Breath is shown in Table 1 first row and secondary series).
The specific probe can be specifically made of following 662 probes：Single strand dna shown in the sequence 1 of sequence table
To the single strand dna shown in the sequence 662 of sequence table.
SNP chip currently used for GWAS be primarily upon with the relevant SNP site of protein coding gene, including being located at egg
White matter encoding gene exon 1 and the SNP site of transcription regulating region, there are no for non-in the range of full-length genome in the world
The SNP chip of encoding gene, the particularly encoding gene of long-chain non-coding RNA, and the relation of long-chain non-coding RNA and disease is
Through more and more being confirmed.
The DNA chip of the SNPs of noncoding region provided by the invention in the range of European crowd's full-length genome, comprising
592 SNP screened from long-chain Noncoding gene region, these SNP are in the transcriptional domain of mankind's Noncoding gene
Representative SNP.
The present invention has great application value for the SNP site detection in mankind's long-chain Noncoding gene region, right
There is great application prospect in the risk assessment of genetic disease and personalized treatment.
Specific embodiment
Following embodiment facilitates a better understanding of the present invention, but does not limit the present invention.Experiment in following embodiments
Method is conventional method unless otherwise specified.Test material used in following embodiments is certainly unless otherwise specified
What routine biochemistry reagent shop was commercially available.Quantitative test in following embodiment is respectively provided with three repeated experiments, as a result makes even
Average.
The screening of embodiment 1, SNPs
The definition in long-chain Noncoding gene region be based on applicant's independent development non-coding RNA database (Xie etc.,
NONCODEv4：exploring the world of long non-coding RNA genes.Nucleic Acids
Res.2014,42：D98-D103.http：//www.noncode.org/).NONCODE databases before about 10 years specially
Door includes the non-coding RNA (except rRNA and tRNA) of each species, up to the present, has been updated to the 5th version, wherein
Newest 144,134 long-chain Noncoding genes comprising the mankind.The present inventor has collected GENCODE plans again
(Harrow etc., GENCODE：the reference human genome annotation for The ENCODE
Project.Genome Research.2012.22：1760-74.http：//www.gencodegenes.org/) issue is most
New mankind's long-chain non-coding RNA data and Human lincRNA catalog data sets (Cabili etc., Integrative
annotation of human large intergenic noncoding RNAs reveals global properties
and specific subclasses.2011.Genes Dev 25：1915-27).Based on above-mentioned data, 26977 are obtained altogether
A long-chain Noncoding gene region.
1877 miRNA precursor sequences of the definition in miR-96 gene region based on the people included in NONCODE databases,
These sequences are also embodied in miRBase databases (Kozomara etc., miRBase：annotating high confidence
microRNAs using deep sequencing data.Nucleic Acids Res.2014.42：D68-D73).
SNP site and genotype data are obtained from the data of the thousand newest issues of human genome plan, only consider European
The genotype data of common SNP site in group.By all SNP sites according to Noncoding gene group areas, then calculate
The r2 values between all SNP sites in each group, filter out representative SNP site, are known as tagSNP.It filters out altogether
The distinctive 592 tag SNP sites positioned at Noncoding gene area of European crowd.
The preparation of embodiment 2, chip
It the information of 592 tag SNP sites and detects the detecting probe information of the SNP site and is shown in Table 1.
Table 1
Note：Probe is single strand dna.
It will be for detecting the probe of above-mentioned each SNP site (the i.e. sequence 1 of sequence table to sequence by Affymetrix companies
Each single strand dna shown in 662) it is separately fixed on substrate, it obtains non-in the range of for European crowd's full-length genome
The DNA chip (Axiom array boards) of the SNPs of code area.
The application of embodiment 3, chip
Using the DNA chip of the SNPs for the noncoding region in the range of European crowd's full-length genome prepared by embodiment 2
Volunteer to be measured is detected, specific method is as follows：
1st, take a blood sample, extract genomic DNA.
2nd, the genomic DNA that about 200ng steps 1 is taken to obtain, using kit (2.0 Reagent Kit of Axiom；
Affymetrix Products, article No. 901758) and operated by kit specification, it is directed to Europe with what embodiment 2 provided
The SNPs of noncoding region in the range of crowd's full-length genome DNA chip hybridization, then on GeneTitan multichannel instruments into
As detection (a kind of color marks of A/T, another color marks of G/C), volunteer to be measured is obtained based on each SNP site
Genotype.
Partial results are shown in Table 2.
Table 2
<110>Institute of Biophysics, Academia Sinica
Guangdong is because of microcycle decoder bio tech ltd
<120>A kind of DNA chip of the SNPs of noncoding region in the range of European crowd's full-length genome
<160> 622
<201> 1
<211> 30
<212> DNA
<213>Artificial sequence
<400> 1
CACCATCACC ACCACCAATG ACAATGACAT 30
<201> 2
<211> 30
<212> DNA
<213>Artificial sequence
<400> 2
TCATTCTTTT CCAAAAACAT CCTCATAGAC 30
<201> 3
<211> 30
<212> DNA
<213>Artificial sequence
<400> 3
CTGTTATTGT GTGTACCACC AAATTTGCCT 30
<201> 4
<211> 30
<212> DNA
<213>Artificial sequence
<400> 4
TAAAGGAAGA TTATATAACA ATTGAAAAAA 30
<201> 5
<211> 30
<212> DNA
<213>Artificial sequence
<400> 5
TAAGTGTTGC AAACTATGAA AAAGCTTTAG 30
<201> 6
<211> 30
<212> DNA
<213>Artificial sequence
<400> 6
AAATAATTAT TATTAAATTC CCTTCCAAAG 30
<201> 7
<211> 30
<212> DNA
<213>Artificial sequence
<400> 7
AATACAAAAT TAGTGGGGCA TGGTGGCACA 30
<201> 8
<211> 30
<212> DNA
<213>Artificial sequence
<400> 8
TTGCAGATAA GATGGTGGCA ACAATTTCAT 30
<201> 9
<211> 30
<212> DNA
<213>Artificial sequence
<400> 9
CAAATCAGGA ATCATGATAG AAAGCCAGGT 30
<201> 10
<211> 30
<212> DNA
<213>Artificial sequence
<400> 10
AGATGTCTTG CAAGAGGGAA GTGGTAACTG 30
<201> 11
<211> 30
<212> DNA
<213>Artificial sequence
<400> 11
AAGGGTCCAA AAATCTAAAA TTACATGATG 30
<201> 12
<211> 30
<212> DNA
<213>Artificial sequence
<400> 12
GACTTCAACT AAGAAGAAGC TGGGTTTTTT 30
<201> 13
<211> 30
<212> DNA
<213>Artificial sequence
<400> 13
TACATTGAAT CCAAGACCTA CCTATTAGTA 30
<201> 14
<211> 30
<212> DNA
<213>Artificial sequence
<400> 14
TATTCACCCA GTCTGTTCTT TGCAGGATGT 30
<201> 15
<211> 30
<212> DNA
<213>Artificial sequence
<400> 15
CACCATACTT GTCACATTCT TACCCTTCAT 30
<201> 16
<211> 30
<212> DNA
<213>Artificial sequence
<400> 16
ACAGGGAGAA GAATGAGATG GTAGAGGAAA 30
<201> 17
<211> 30
<212> DNA
<213>Artificial sequence
<400> 17
GAAATCTTCT CCCCTAAGAA CTGGAACAAG 30
<201> 18
<211> 30
<212> DNA
<213>Artificial sequence
<400> 18
CTGGAGTGCA GTGGTACGAT CTCAGCTGAC 30
<201> 19
<211> 30
<212> DNA
<213>Artificial sequence
<400> 19
CTTCTACGCA TTTTTAGGAT ATATGGAGCT 30
<201> 20
<211> 30
<212> DNA
<213>Artificial sequence
<400> 20
TTGCAAAGTT TTATCTTCCT ATTCTAAAAA 30
<201> 21
<211> 30
<212> DNA
<213>Artificial sequence
<400> 21
GCCTTGAATT CCAAGACATT CAAGCCACCC 30
<201> 22
<211> 30
<212> DNA
<213>Artificial sequence
<400> 22
GCCTTGAATT CCAAGACATT CAAGCCACCC 30
<201> 23
<211> 30
<212> DNA
<213>Artificial sequence
<400> 23
TCTGAGTTTC AGGTACTATA AATGTGCTTT 30
<201> 24
<211> 30
<212> DNA
<213>Artificial sequence
<400> 24
AGCTCCCATC CTCCCATCCC CCCAACCTCA 30
<201> 25
<211> 30
<212> DNA
<213>Artificial sequence
<400> 25
GAGGAGATGG AATCATTCAT TTGATTGGAG 30
<201> 26
<211> 30
<212> DNA
<213>Artificial sequence
<400> 26
ATTGAATACC CTTTATTTCT TTCTCTTGCC 30
<201> 27
<211> 30
<212> DNA
<213>Artificial sequence
<400> 27
ACATAGAACT GCCTTGAACT TCATTCTAGT 30
<201> 28
<211> 30
<212> DNA
<213>Artificial sequence
<400> 28
ATATGTGTAA GGAAGGTCTG AGCAGAGGGT 30
<201> 29
<211> 30
<212> DNA
<213>Artificial sequence
<400> 29
CATAGTTCAG TTTCTTTACA TGGTGAGTCC 30
<201> 30
<211> 30
<212> DNA
<213>Artificial sequence
<400> 30
GTCACCACGC CCGGCTAATT TTGTATTTTC 30
<201> 31
<211> 30
<212> DNA
<213>Artificial sequence
<400> 31
GAGTGCCGAT TGGTGTATTT ACAATCCCTG 30
<201> 32
<211> 30
<212> DNA
<213>Artificial sequence
<400> 32
ATTTACAACA AAATGATAAA GTAATTGTGG 30
<201> 33
<211> 30
<212> DNA
<213>Artificial sequence
<400> 33
CCCCAGCTCT CAACACCACC ACAATGAAGA 30
<201> 34
<211> 30
<212> DNA
<213>Artificial sequence
<400> 34
GATGGTCTTT ATCTCCTGAC CTCGTGATCC 30
<201> 35
<211> 30
<212> DNA
<213>Artificial sequence
<400> 35
GATGGTCTTT ATCTCCTGAC CTCGTGATCC 30
<201> 36
<211> 30
<212> DNA
<213>Artificial sequence
<400> 36
GGAAAAAGGG TTTAATGGAC TTACATTTCA 30
<201> 37
<211> 30
<212> DNA
<213>Artificial sequence
<400> 37
ACCAATTGAC ACTCCCACCT GCACTGTGAA 30
<201> 38
<211> 30
<212> DNA
<213>Artificial sequence
<400> 38
CCAGGAGACC CTGAGAACAT GTGCCCAAGG 30
<201> 39
<211> 30
<212> DNA
<213>Artificial sequence
<400> 39
TGTCATCATT ATCCCACCAC CAAAAATTCA 30
<201> 40
<211> 30
<212> DNA
<213>Artificial sequence
<400> 40
AACAATATAA ATCAAAGGAA ACATATTTAT 30
<201> 41
<211> 30
<212> DNA
<213>Artificial sequence
<400> 41
TTTATAATTA TAATGAACTT ACATATACAA 30
<201> 42
<211> 30
<212> DNA
<213>Artificial sequence
<400> 42
TACAAGGAAC TCAAACAACA GTAAAAATAT 30
<201> 43
<211> 30
<212> DNA
<213>Artificial sequence
<400> 43
CCAGCCAAAT TGTACCTTTT AAAGATAAAA 30
<201> 44
<211> 30
<212> DNA
<213>Artificial sequence
<400> 44
GAAAGTCAGT GATGCTCTTG GAAGAATTTC 30
<201> 45
<211> 30
<212> DNA
<213>Artificial sequence
<400> 45
CTGGTACCAT TCCTTCTGAA ACTGTTCCAA 30
<201> 46
<211> 30
<212> DNA
<213>Artificial sequence
<400> 46
TAAGAATGAC TCCCCAAAAC CTCAGCTGTA 30
<201> 47
<211> 30
<212> DNA
<213>Artificial sequence
<400> 47
AAACAAAAAG AAGCAGCAAC TTACAATTCC 30
<201> 48
<211> 30
<212> DNA
<213>Artificial sequence
<400> 48
GAATGAATGC TACATGGCAG TGACTTTGTC 30
<201> 49
<211> 30
<212> DNA
<213>Artificial sequence
<400> 49
GAATGAATGC TACATGGCAG TGACTTTGTC 30
<201> 50
<211> 30
<212> DNA
<213>Artificial sequence
<400> 50
CACACACACC CCATATTCGG AGTCTTTATA 30
<201> 51
<211> 30
<212> DNA
<213>Artificial sequence
<400> 51
TTCCATTGTA AAGAATACTC AAATGCCATT 30
<201> 52
<211> 30
<212> DNA
<213>Artificial sequence
<400> 52
GTTATAAGTT TATATTATTA TAAATTATAA 30
<201> 53
<211> 30
<212> DNA
<213>Artificial sequence
<400> 53
CCAAGTCTTC CCATTATAAA CACTGGCCTA 30
<201> 54
<211> 30
<212> DNA
<213>Artificial sequence
<400> 54
AGGAAGGCGG GGATACCTGG GAAATAAACA 30
<201> 55
<211> 30
<212> DNA
<213>Artificial sequence
<400> 55
TCCCCAGGTG ACACCGTAAG TGACAGAGTC 30
<201> 56
<211> 30
<212> DNA
<213>Artificial sequence
<400> 56
GTTAAAACCT TATAGAAACT AATCAAAGCT 30
<201> 57
<211> 30
<212> DNA
<213>Artificial sequence
<400> 57
ACTCCAGCCT GGGTGACAGA GGGAGACTCC 30
<201> 58
<211> 30
<212> DNA
<213>Artificial sequence
<400> 58
GCTCAATTTC TCTGGGCCTC TGGGTGCTTT 30
<201> 59
<211> 30
<212> DNA
<213>Artificial sequence
<400> 59
ACCCAGCAGA AGAAAGAATT AGTAGCTTGA 30
<201> 60
<211> 30
<212> DNA
<213>Artificial sequence
<400> 60
AAAAGATAGA AAACTAGCAA CTTACAAAGA 30
<201> 61
<211> 30
<212> DNA
<213>Artificial sequence
<400> 61
CATCTACCTA TGGAAGAGAA ATAGAAAATA 30
<201> 62
<211> 30
<212> DNA
<213>Artificial sequence
<400> 62
GTATTTTTAG TAGAGACGGG GTTTTCCCGT 30
<201> 63
<211> 30
<212> DNA
<213>Artificial sequence
<400> 63
GTATTTTTAG TAGAGACGGG GTTTTCCCGT 30
<201> 64
<211> 30
<212> DNA
<213>Artificial sequence
<400> 64
GATCTTTGAC AAACCTGAGA AAAACAAGCA 30
<201> 65
<211> 30
<212> DNA
<213>Artificial sequence
<400> 65
GTCTCGATCT CCTGCCCTCG TGATCCACCC 30
<201> 66
<211> 30
<212> DNA
<213>Artificial sequence
<400> 66
TACACATAAT ACACACATAC ACATGTGCAC 30
<201> 67
<211> 30
<212> DNA
<213>Artificial sequence
<400> 67
ATTTGGGTTA TAATCTAATA CTGTCCTTTT 30
<201> 68
<211> 30
<212> DNA
<213>Artificial sequence
<400> 68
AATGAACATT TTTTAAATCA TCTCACAGCC 30
<201> 69
<211> 30
<212> DNA
<213>Artificial sequence
<400> 69
AAGTTTATCA ATCCAAGAAA GAGAGAAAAG 30
<201> 70
<211> 30
<212> DNA
<213>Artificial sequence
<400> 70
CTGGATTTTG TGTTTTTAAC CTCTGTGCTA 30
<201> 71
<211> 30
<212> DNA
<213>Artificial sequence
<400> 71
TAAATTATCT TCCTGTGTGT GCGTTTTTTC 30
<201> 72
<211> 30
<212> DNA
<213>Artificial sequence
<400> 72
ATGATTTTCA GATTAATGCT AAAATGCCAT 30
<201> 73
<211> 30
<212> DNA
<213>Artificial sequence
<400> 73
CTTCTACACA TCAAAAGAAA CAGTCAACAA 30
<201> 74
<211> 30
<212> DNA
<213>Artificial sequence
<400> 74
TTGTATTTTT AGTACATATG GGGTTTCACC 30
<201> 75
<211> 30
<212> DNA
<213>Artificial sequence
<400> 75
TCCAGAGCCT AACATCCTTG AATTCACAAA 30
<201> 76
<211> 30
<212> DNA
<213>Artificial sequence
<400> 76
TCAACGTGAG GATTTGGAAA TAAAGGTGGC 30
<201> 77
<211> 30
<212> DNA
<213>Artificial sequence
<400> 77
AAATGAAAGA GAAGGGAGTC AAAAGATATC 30
<201> 78
<211> 30
<212> DNA
<213>Artificial sequence
<400> 78
ACAACAATAA GGAGAGGAGG TTGAATTCAA 30
<201> 79
<211> 30
<212> DNA
<213>Artificial sequence
<400> 79
ATAACAATAA ACTGCCTCTA CTTAAAGTGT 30
<201> 80
<211> 30
<212> DNA
<213>Artificial sequence
<400> 80
TGAGACGTGA AGCGAGGCAG GATGGCTGAG 30
<201> 81
<211> 30
<212> DNA
<213>Artificial sequence
<400> 81
GTCACTTGAT CTCTTCCAGG CTTTCACTCT 30
<201> 82
<211> 30
<212> DNA
<213>Artificial sequence
<400> 82
GGGAGGATCA CTCGAGCCCA GAAGGTTGAC 30
<201> 83
<211> 30
<212> DNA
<213>Artificial sequence
<400> 83
AAAAGCAAAA CCTTGCAGTA TGTACAGCCC 30
<201> 84
<211> 30
<212> DNA
<213>Artificial sequence
<400> 84
TTGACTTAAA AAGCGAGGGA TGTTTTCATA 30
<201> 85
<211> 30
<212> DNA
<213>Artificial sequence
<400> 85
CAGAAAGACA GTCAGTTTTC TGTTAGGGTT 30
<201> 86
<211> 30
<212> DNA
<213>Artificial sequence
<400> 86
TCAGATAAAT GTCCTTGTTT TAACATTGTT 30
<201> 87
<211> 30
<212> DNA
<213>Artificial sequence
<400> 87
TTATTGATAC TTATTTTATG GAGTTAGAAT 30
<201> 88
<211> 30
<212> DNA
<213>Artificial sequence
<400> 88
AAATAGACCC AGACTTAAAT GGTTAGTAGA 30
<201> 89
<211> 30
<212> DNA
<213>Artificial sequence
<400> 89
AGTATTTTCT AAATATAAGT TACATATTAA 30
<201> 90
<211> 30
<212> DNA
<213>Artificial sequence
<400> 90
TGAGGAAGGG TGCAGGGTGG TGTCTATATG 30
<201> 91
<211> 30
<212> DNA
<213>Artificial sequence
<400> 91
TGAGGAAGGG TGCAGGGTGG TGTCTATATG 30
<201> 92
<211> 30
<212> DNA
<213>Artificial sequence
<400> 92
AACACTGGAA CTTTGATTGA CTACAACCTC 30
<201> 93
<211> 30
<212> DNA
<213>Artificial sequence
<400> 93
GCTATGGTGC TTCCCAAGAG CCCAGACATC 30
<201> 94
<211> 30
<212> DNA
<213>Artificial sequence
<400> 94
CTCCTCATCC AACTGAAATT TTTTAAAAAT 30
<201> 95
<211> 30
<212> DNA
<213>Artificial sequence
<400> 95
TACTCTATTC CTTAGAAGCA GGTCACTAAG 30
<201> 96
<211> 30
<212> DNA
<213>Artificial sequence
<400> 96
AAGGAGAAGA TTTGTGCTAT TATTAAAATC 30
<201> 97
<211> 30
<212> DNA
<213>Artificial sequence
<400> 97
GCTAAATTCT GTATGGGCAT AATTAGAATC 30
<201> 98
<211> 30
<212> DNA
<213>Artificial sequence
<400> 98
TCACTCACTA ATGAGAGTGG TACCAAGCTA 30
<201> 99
<211> 30
<212> DNA
<213>Artificial sequence
<400> 99
CTTCCTCCTT CACTCGCCTT ACAAAGTTAC 30
<201> 100
<211> 30
<212> DNA
<213>Artificial sequence
<400> 100
CCAGGACCCA GGAACTTCTA TTCCCTCCCA 30
<201> 101
<211> 30
<212> DNA
<213>Artificial sequence
<400> 101
TCCTGCTTTC TTCTGCTTTC TTTGTACCCA 30
<201> 102
<211> 30
<212> DNA
<213>Artificial sequence
<400> 102
GTGACAGGTA TTAGAGGAAT AGTTACTTAC 30
<201> 103
<211> 30
<212> DNA
<213>Artificial sequence
<400> 103
AGTATATGAA CAATTCAAAC TAAAAAATAC 30
<201> 104
<211> 30
<212> DNA
<213>Artificial sequence
<400> 104
AAATTGTATG GGATATCTAA AATTCTAAGG 30
<201> 105
<211> 30
<212> DNA
<213>Artificial sequence
<400> 105
AAATTGTATG GGATATCTAA AATTCTAAGG 30
<201> 106
<211> 30
<212> DNA
<213>Artificial sequence
<400> 106
TTATACAGCA ATGAGAATAA GCATATTAGA 30
<201> 107
<211> 30
<212> DNA
<213>Artificial sequence
<400> 107
TACACCTCCC ACCATTTCTC CTGCCTGTTA 30
<201> 108
<211> 30
<212> DNA
<213>Artificial sequence
<400> 108
GGGTAATAAT AGTTAACTTT CTTTTCTTTG 30
<201> 109
<211> 30
<212> DNA
<213>Artificial sequence
<400> 109
GTCATAAAGT AACAAGTAAC AGAGGTTTTT 30
<201> 110
<211> 30
<212> DNA
<213>Artificial sequence
<400> 110
TCAGGATTAA TATAAGATTA AATAAAATAA 30
<201> 111
<211> 30
<212> DNA
<213>Artificial sequence
<400> 111
TGAAAGACAG AGTGAGACTC CATCTCAAAA 30
<201> 112
<211> 30
<212> DNA
<213>Artificial sequence
<400> 112
GTGATATTTT CCTGTTGTAC TAGTCTTTTA 30
<201> 113
<211> 30
<212> DNA
<213>Artificial sequence
<400> 113
TTGTGAAGCT AGGATTTGAG CCAGAAATTT 30
<201> 114
<211> 30
<212> DNA
<213>Artificial sequence
<400> 114
CCCAACTAAG GAAATTGATC CAGGTTATCA 30
<201> 115
<211> 30
<212> DNA
<213>Artificial sequence
<400> 115
TCTGTTAATT ATGTCTAAGG CCCAGTACTA 30
<201> 116
<211> 30
<212> DNA
<213>Artificial sequence
<400> 116
GGAACATGCC TGTAATCTCA GCTACTCTCG 30
<201> 117
<211> 30
<212> DNA
<213>Artificial sequence
<400> 117
ATTGAGACAA GAAAAATTTG GAACTAGTCC 30
<201> 118
<211> 30
<212> DNA
<213>Artificial sequence
<400> 118
TCTCCAACTC CTGACCTCAA GTGATCCACC 30
<201> 119
<211> 30
<212> DNA
<213>Artificial sequence
<400> 119
GAACATAGTT TCCCAGTACA TGAAAGTTTG 30
<201> 120
<211> 30
<212> DNA
<213>Artificial sequence
<400> 120
CAAGATAAAA TAAAACAAGA AGAGTTGATA 30
<201> 121
<211> 30
<212> DNA
<213>Artificial sequence
<400> 121
TTCAAATTAA AATCACAATT AGATACCATA 30
<201> 122
<211> 30
<212> DNA
<213>Artificial sequence
<400> 122
GTCATGAAGC TTTGTCATAC CTCATTAAGC 30
<201> 123
<211> 30
<212> DNA
<213>Artificial sequence
<400> 123
AGTATTATAA GCCTGGATAA TTTGACTAAA 30
<201> 124
<211> 30
<212> DNA
<213>Artificial sequence
<400> 124
GAGACCTCAG AGAATGTGCA ACAAACCCCA 30
<201> 125
<211> 30
<212> DNA
<213>Artificial sequence
<400> 125
TCTCCACCCT CCTCCCAATA AAATAAAAAA 30
<201> 126
<211> 30
<212> DNA
<213>Artificial sequence
<400> 126
TCACCCACCT CCTGAGATCT TACTGGGAAG 30
<201> 127
<211> 30
<212> DNA
<213>Artificial sequence
<400> 127
CCCCTCCCCA TTGTGTCACA ACCCCTCTGT 30
<201> 128
<211> 30
<212> DNA
<213>Artificial sequence
<400> 128
AATTCCAAGA TTGCCAGACA TTTAAACAAG 30
<201> 129
<211> 30
<212> DNA
<213>Artificial sequence
<400> 129
AATTCCAAGA TTGCCAGACA TTTAAACAAG 30
<201> 130
<211> 30
<212> DNA
<213>Artificial sequence
<400> 130
ACAAAGAAGG ATGAGAGAGA TAATATTCCC 30
<201> 131
<211> 30
<212> DNA
<213>Artificial sequence
<400> 131
ACTATTATAA AATGTGACTC TCTCTCCAAA 30
<201> 132
<211> 30
<212> DNA
<213>Artificial sequence
<400> 132
CTGGACAACT AGAGTTCCCA CACCACATGC 30
<201> 133
<211> 30
<212> DNA
<213>Artificial sequence
<400> 133
AAAAAATTAG ACAGGCATGT TGACGGGTGC 30
<201> 134
<211> 30
<212> DNA
<213>Artificial sequence
<400> 134
GAGCAGATGG AAGAAAGAGA GAGGAAGGGG 30
<201> 135
<211> 30
<212> DNA
<213>Artificial sequence
<400> 135
TCTCCTGACT TCCTCGTGAT CCGCCCGCCT 30
<201> 136
<211> 30
<212> DNA
<213>Artificial sequence
<400> 136
GAGCCCTCTC TGCGTGGGGA TGAGGAGGCT 30
<201> 137
<211> 30
<212> DNA
<213>Artificial sequence
<400> 137
AACTCAGGAT TAAGAAACTC ACTCAAAACC 30
<201> 138
<211> 30
<212> DNA
<213>Artificial sequence
<400> 138
AAACTATTCC AAACAATTTG AAAAGAGAGA 30
<201> 139
<211> 30
<212> DNA
<213>Artificial sequence
<400> 139
CGTTTGCTTC CTGTCCCATG ACTTTATCCT 30
<201> 140
<211> 30
<212> DNA
<213>Artificial sequence
<400> 140
CTCCCCATTT CAAGTGATTC TCCTCCCTCA 30
<201> 141
<211> 30
<212> DNA
<213>Artificial sequence
<400> 141
AACATGTAAG AGGCCGGGCG CGGTGGCTCA 30
<201> 142
<211> 30
<212> DNA
<213>Artificial sequence
<400> 142
CATCTCTACT GAAAATACAA AAAATTAGGT 30
<201> 143
<211> 30
<212> DNA
<213>Artificial sequence
<400> 143
CAGCCCTGAC CCGATTAATT CCCTTTCATC 30
<201> 144
<211> 30
<212> DNA
<213>Artificial sequence
<400> 144
GTTCAGGGTT TTCCTGGCTT TCAGAGCGAA 30
<201> 145
<211> 30
<212> DNA
<213>Artificial sequence
<400> 145
CCCATTCACA CACACATTCA CACACATTGA 30
<201> 146
<211> 30
<212> DNA
<213>Artificial sequence
<400> 146
CCTAAAATGT ATATGGAACC TCAAAAGACC 30
<201> 147
<211> 30
<212> DNA
<213>Artificial sequence
<400> 147
AATACAAAAA TTAGCCAGGC ATGGTGGTGC 30
<201> 148
<211> 30
<212> DNA
<213>Artificial sequence
<400> 148
CCACTGCAAA AACATGTCAA ATTGTAGAGA 30
<201> 149
<211> 30
<212> DNA
<213>Artificial sequence
<400> 149
TAAGGTTCAA AAGCAACAAT GTTACAGAGG 30
<201> 150
<211> 30
<212> DNA
<213>Artificial sequence
<400> 150
CTTCCCGAAG GCAGGACTAA TCTTCCCCAC 30
<201> 151
<211> 30
<212> DNA
<213>Artificial sequence
<400> 151
AACTACTTTA AATTTCATAT GGGACCAGAC 30
<201> 152
<211> 30
<212> DNA
<213>Artificial sequence
<400> 152
AGTTAACAGG TAGTGGAGGA TAGATAGGGG 30
<201> 153
<211> 30
<212> DNA
<213>Artificial sequence
<400> 153
AGTTAACAGG TAGTGGAGGA TAGATAGGGG 30
<201> 154
<211> 30
<212> DNA
<213>Artificial sequence
<400> 154
GAGCTTATTC CACATTTTCC ATATAGATAT 30
<201> 155
<211> 30
<212> DNA
<213>Artificial sequence
<400> 155
GGAGGCGGAG GTTGCAGTGG GCCAAGATGG 30
<201> 156
<211> 30
<212> DNA
<213>Artificial sequence
<400> 156
CAGGTGAGGC ACCTGCACGC ACACCTAGCT 30
<201> 157
<211> 30
<212> DNA
<213>Artificial sequence
<400> 157
ATTCCAGCTC TAAGATTGAC GAGGTAAAAA 30
<201> 158
<211> 30
<212> DNA
<213>Artificial sequence
<400> 158
ATCTTTCCTT TCGCTCTTCA GACCTAGAGG 30
<201> 159
<211> 30
<212> DNA
<213>Artificial sequence
<400> 159
ACCCCACAAT TCCTACATGG AAGCCCTAGC 30
<201> 160
<211> 30
<212> DNA
<213>Artificial sequence
<400> 160
GCAACTCTAC AAAAATAAGC TTTTAACACT 30
<201> 161
<211> 30
<212> DNA
<213>Artificial sequence
<400> 161
GCAGTGCTGG GGTTCAAACA AGTTGTCTCC 30
<201> 162
<211> 30
<212> DNA
<213>Artificial sequence
<400> 162
TGGCTCACTC CTGTAAACCC AGTGTTTTTG 30
<201> 163
<211> 30
<212> DNA
<213>Artificial sequence
<400> 163
CAAGATGCTC ATGTGTTTCA CTTTAAGGTT 30
<201> 164
<211> 30
<212> DNA
<213>Artificial sequence
<400> 164
AAAGCAGCGA CTTTATTCCT AGCTTTCCAC 30
<201> 165
<211> 30
<212> DNA
<213>Artificial sequence
<400> 165
TACCCAAACA GGAAATCCAC AAGTTTTAAA 30
<201> 166
<211> 30
<212> DNA
<213>Artificial sequence
<400> 166
TTCCCTTTGT CTGAAGCCAG TTGGATTCTC 30
<201> 167
<211> 30
<212> DNA
<213>Artificial sequence
<400> 167
AAAACATTGG GCCAGGAACT TGACCACATC 30
<201> 168
<211> 30
<212> DNA
<213>Artificial sequence
<400> 168
ACTTGTTTCT GATCCACAGA ATATGCTACA 30
<201> 169
<211> 30
<212> DNA
<213>Artificial sequence
<400> 169
CAGAACACAC ATGCTTTCTC ACTGACACAC 30
<201> 170
<211> 30
<212> DNA
<213>Artificial sequence
<400> 170
CACTCTAGCC TGGGTGACAG AGCGAGACTC 30
<201> 171
<211> 30
<212> DNA
<213>Artificial sequence
<400> 171
TATTTAATTT TGAGACAGAG TTTCGCTCTT 30
<201> 172
<211> 30
<212> DNA
<213>Artificial sequence
<400> 172
CTACTAAAAA TACAAAAATT AGCCGGGCAC 30
<201> 173
<211> 30
<212> DNA
<213>Artificial sequence
<400> 173
TGGGGGAAAC CACACCCATG ATTCAATTAT 30
<201> 174
<211> 30
<212> DNA
<213>Artificial sequence
<400> 174
CAGGAGGATC CCTTGAGCCC AGGAGTTTGA 30
<201> 175
<211> 30
<212> DNA
<213>Artificial sequence
<400> 175
AAACCTAGGC AACACCATTC AGGACATAGG 30
<201> 176
<211> 30
<212> DNA
<213>Artificial sequence
<400> 176
GGTTCAAGGA CTACTCCTGC CTCAGCCTCC 30
<201> 177
<211> 30
<212> DNA
<213>Artificial sequence
<400> 177
TTCATTTTCA GGTAAATTTT GCTGTCATCT 30
<201> 178
<211> 30
<212> DNA
<213>Artificial sequence
<400> 178
TCTCAAACTC CTGACCTCGT GATCTGCCCT 30
<201> 179
<211> 30
<212> DNA
<213>Artificial sequence
<400> 179
AGAATGGTGT GAACCCGGGA GGCGGAGCTT 30
<201> 180
<211> 30
<212> DNA
<213>Artificial sequence
<400> 180
GAAGGGAGGG GCCTGGCGCG GTGGCTCACG 30
<201> 181
<211> 30
<212> DNA
<213>Artificial sequence
<400> 181
TTAGTTGCAT AACCTAACTT AGGAAAAACA 30
<201> 182
<211> 30
<212> DNA
<213>Artificial sequence
<400> 182
CACAGACAAG CATCTTTTCC ACAACTAAGG 30
<201> 183
<211> 30
<212> DNA
<213>Artificial sequence
<400> 183
TCTGTGTGTG GAAATGCTGG AGGATGAAAC 30
<201> 184
<211> 30
<212> DNA
<213>Artificial sequence
<400> 184
ATTGGCTTTG TAGAATATCC AAATTTAGTA 30
<201> 185
<211> 30
<212> DNA
<213>Artificial sequence
<400> 185
TTTTTAGGTT TACATTCCAA ACTCCCAAAC 30
<201> 186
<211> 30
<212> DNA
<213>Artificial sequence
<400> 186
GTGACGCTCA CTGAGACTGT GCTAAGATCC 30
<201> 187
<211> 30
<212> DNA
<213>Artificial sequence
<400> 187
AAAACAAATG CTGTTATCGA TACCAAAATC 30
<201> 188
<211> 30
<212> DNA
<213>Artificial sequence
<400> 188
AACTATTGAA TGGTACAGTT TGAGATCTTC 30
<201> 189
<211> 30
<212> DNA
<213>Artificial sequence
<400> 189
TAATTATCTG ACACCACCCA CTCAACTCTA 30
<201> 190
<211> 30
<212> DNA
<213>Artificial sequence
<400> 190
AGCTCTCACT AAGAAGGATG AAAGCAGAAA 30
<201> 191
<211> 30
<212> DNA
<213>Artificial sequence
<400> 191
TTACATGGCA GCAGGCAAGA GAGGGCTTAT 30
<201> 192
<211> 30
<212> DNA
<213>Artificial sequence
<400> 192
AAATCACAGT AGTTGACAGT AACAGTTCGC 30
<201> 193
<211> 30
<212> DNA
<213>Artificial sequence
<400> 193
TGAACTCCAT AGGCCCGCAT TCTAATAGAG 30
<201> 194
<211> 30
<212> DNA
<213>Artificial sequence
<400> 194
TTCTGGACTG TTTGCTTATA GGCCCAGAGA 30
<201> 195
<211> 30
<212> DNA
<213>Artificial sequence
<400> 195
GAGGCAGGAG AATTGCTTGA GCTGGGAGGC 30
<201> 196
<211> 30
<212> DNA
<213>Artificial sequence
<400> 196
TGTCTACTTT ATTATTTTTC CTTCCTGTGC 30
<201> 197
<211> 30
<212> DNA
<213>Artificial sequence
<400> 197
TTTGACTAAC TGATAACAAC AAAACTTATA 30
<201> 198
<211> 30
<212> DNA
<213>Artificial sequence
<400> 198
ACTCACAACT CCTGCTCAGT TTCTTGGTTG 30
<201> 199
<211> 30
<212> DNA
<213>Artificial sequence
<400> 199
TGGTAACCGC AGAAGTCGAT GAGTAGGAAC 30
<201> 200
<211> 30
<212> DNA
<213>Artificial sequence
<400> 200
GAGTGAACCA ATGAATGAAC AAGATGGGAA 30
<201> 201
<211> 30
<212> DNA
<213>Artificial sequence
<400> 201
TATGAAGCCA GAATCACCCT AATACCACAA 30
<201> 202
<211> 30
<212> DNA
<213>Artificial sequence
<400> 202
CTGCATCCTG AAGTTGGGTA CCTGATGCCC 30
<201> 203
<211> 30
<212> DNA
<213>Artificial sequence
<400> 203
ATTCTTTTAA TCCCAATGTG TATGTTGACT 30
<201> 204
<211> 30
<212> DNA
<213>Artificial sequence
<400> 204
ATTCTTTTAA TCCCAATGTG TATGTTGACT 30
<201> 205
<211> 30
<212> DNA
<213>Artificial sequence
<400> 205
TAGCTATGAG AAGAGAGGTG TGGGAACTGG 30
<201> 206
<211> 30
<212> DNA
<213>Artificial sequence
<400> 206
TCATTTTGTT GACCTCTCCC ACCTTTAACA 30
<201> 207
<211> 30
<212> DNA
<213>Artificial sequence
<400> 207
TTGTCTGCCC TTCAATGTTT CCATGAGCTT 30
<201> 208
<211> 30
<212> DNA
<213>Artificial sequence
<400> 208
AAACAGCTGA AATTTCTTGA ACACCCTGGC 30
<201> 209
<211> 30
<212> DNA
<213>Artificial sequence
<400> 209
CCTGCCCTCC CCTCCCTACC TGCTGCCTGC 30
<201> 210
<211> 30
<212> DNA
<213>Artificial sequence
<400> 210
CCAAGTTACA GGTTGTAAAA GAGAACAAAA 30
<201> 211
<211> 30
<212> DNA
<213>Artificial sequence
<400> 211
GGTGGAAGTT GCAGTGAGCC GAGATCGCGC 30
<201> 212
<211> 30
<212> DNA
<213>Artificial sequence
<400> 212
CGTCCTTACC AAGAAAATAT ACAAAAATTC 30
<201> 213
<211> 30
<212> DNA
<213>Artificial sequence
<400> 213
GACTTCTCAT GAGATCTGCT TGTTTAAACA 30
<201> 214
<211> 30
<212> DNA
<213>Artificial sequence
<400> 214
ACCACATAAA TAGAATTAAA AATAAAAACC 30
<201> 215
<211> 30
<212> DNA
<213>Artificial sequence
<400> 215
TGTGAAATTT TGTTGAGTTT GTAAATTTAG 30
<201> 216
<211> 30
<212> DNA
<213>Artificial sequence
<400> 216
TCTGTAGGAA CCAGCCCAGC CATGCTGCCA 30
<201> 217
<211> 30
<212> DNA
<213>Artificial sequence
<400> 217
TGACAGTGGA TTGGCAAGCG AGAGTGGAAC 30
<201> 218
<211> 30
<212> DNA
<213>Artificial sequence
<400> 218
GGTAAGCCTC CTAGACGCCT GTATTGTGCC 30
<201> 219
<211> 30
<212> DNA
<213>Artificial sequence
<400> 219
TACAATTCAA GATGAGATTT AAGTGAGGAC 30
<201> 220
<211> 30
<212> DNA
<213>Artificial sequence
<400> 220
TGATACAATT TTTCTCCAAA AAACACTGTC 30
<201> 221
<211> 30
<212> DNA
<213>Artificial sequence
<400> 221
AGACCAGAAG AGAACCCACT GCCTCGAAAG 30
<201> 222
<211> 30
<212> DNA
<213>Artificial sequence
<400> 222
TTCGGGGGAA AGCTAATGGC CCATTGGAAG 30
<201> 223
<211> 30
<212> DNA
<213>Artificial sequence
<400> 223
AAGGACAGCC CAAGTGGTTG ATGGTAGCAG 30
<201> 224
<211> 30
<212> DNA
<213>Artificial sequence
<400> 224
AAATCAGTGC CTTCAACATC CCCGCCCCAT 30
<201> 225
<211> 30
<212> DNA
<213>Artificial sequence
<400> 225
TGAGTCTGAT TCTATCTGAA TCACTGTACC 30
<201> 226
<211> 30
<212> DNA
<213>Artificial sequence
<400> 226
AGGTGTACAC TTAAGAAAAA ATAATATAAA 30
<201> 227
<211> 30
<212> DNA
<213>Artificial sequence
<400> 227
TGGCCAGGTC GGTTTTGCCC ATCTGTAAAA 30
<201> 228
<211> 30
<212> DNA
<213>Artificial sequence
<400> 228
ACTAATCTAC TTTGTTTCTA TGGATTTGCC 30
<201> 229
<211> 30
<212> DNA
<213>Artificial sequence
<400> 229
GCCCCCTCCC ATCCTGAATG CTGCCCAGAT 30
<201> 230
<211> 30
<212> DNA
<213>Artificial sequence
<400> 230
TATGTACCAA TGACTTCAGA AAAAGTTAAA 30
<201> 231
<211> 30
<212> DNA
<213>Artificial sequence
<400> 231
TTTTCTTCTG TTTCCCGAGC TCTCTCCCTC 30
<201> 232
<211> 30
<212> DNA
<213>Artificial sequence
<400> 232
GGCAAAGGAG GAGAGACTTC TGGCTACCAG 30
<201> 233
<211> 30
<212> DNA
<213>Artificial sequence
<400> 233
AGAACTAGAC AGAGAGAATC TTCATGCCAT 30
<201> 234
<211> 30
<212> DNA
<213>Artificial sequence
<400> 234
TAACTGAGCT CCCTTCTTCT GAACTCCAAA 30
<201> 235
<211> 30
<212> DNA
<213>Artificial sequence
<400> 235
AAGATCATTA CAGGACCCAG CATGAGAAGG 30
<201> 236
<211> 30
<212> DNA
<213>Artificial sequence
<400> 236
TCCATGGGGC TAACTCGCTC ACTTCCTTTA 30
<201> 237
<211> 30
<212> DNA
<213>Artificial sequence
<400> 237
TGGAGTGTAA CATCCAGAGG ATATCTGGCC 30
<201> 238
<211> 30
<212> DNA
<213>Artificial sequence
<400> 238
TGACATCCTT TCTTTCTGTC CAAATGGCAC 30
<201> 239
<211> 30
<212> DNA
<213>Artificial sequence
<400> 239
AGTCTTTCCA ACCTCTTGCT ACATTCTCAC 30
<201> 240
<211> 30
<212> DNA
<213>Artificial sequence
<400> 240
AAGAGAGGTC TCCTTGTAGC TTCTGAGAAA 30
<201> 241
<211> 30
<212> DNA
<213>Artificial sequence
<400> 241
CTTCAACTAC CTTTTCCAGA GAACACAATT 30
<201> 242
<211> 30
<212> DNA
<213>Artificial sequence
<400> 242
CTTCAACTAC CTTTTCCAGA GAACACAATT 30
<201> 243
<211> 30
<212> DNA
<213>Artificial sequence
<400> 243
ATTGTTCATT GCAAGCATAT AGAAATACAA 30
<201> 244
<211> 30
<212> DNA
<213>Artificial sequence
<400> 244
TCTAATAAAA AATTCAAAGA TATTAGTGAC 30
<201> 245
<211> 30
<212> DNA
<213>Artificial sequence
<400> 245
GGAATCTATT GACTCATAGC TTTCAAACAC 30
<201> 246
<211> 30
<212> DNA
<213>Artificial sequence
<400> 246
GGATTGCAAG CATGAGCCAT CGCACCTGGC 30
<201> 247
<211> 30
<212> DNA
<213>Artificial sequence
<400> 247
AGGATCAGTT ATAATCAGTT GTGAGCAAGG 30
<201> 248
<211> 30
<212> DNA
<213>Artificial sequence
<400> 248
ATTACCGCTC ATCGTTCACA TTTAATATTG 30
<201> 249
<211> 30
<212> DNA
<213>Artificial sequence
<400> 249
ATTCATGAGA TGCCTGCCTG TTCCCCGTGG 30
<201> 250
<211> 30
<212> DNA
<213>Artificial sequence
<400> 250
CATGGTATTA GATAGTGTCT TTTCAGAATA 30
<201> 251
<211> 30
<212> DNA
<213>Artificial sequence
<400> 251
GGAGGGCTTT CCCTAATTTC AATCTCCCAC 30
<201> 252
<211> 30
<212> DNA
<213>Artificial sequence
<400> 252
CATTGGTGTG AAACGATTTG TTTTGTGTGA 30
<201> 253
<211> 30
<212> DNA
<213>Artificial sequence
<400> 253
GTAACAGCCA GGAAACCATT TGAAAACCTC 30
<201> 254
<211> 30
<212> DNA
<213>Artificial sequence
<400> 254
TGTGCATTTG TGTATCCAGA GTAAACTAGG 30
<201> 255
<211> 30
<212> DNA
<213>Artificial sequence
<400> 255
CAGAGCCTAT CACTTACCAA ACATGTTCGC 30
<201> 256
<211> 30
<212> DNA
<213>Artificial sequence
<400> 256
AGATATCATA GTGACTGACA ATTGCCTGTA 30
<201> 257
<211> 30
<212> DNA
<213>Artificial sequence
<400> 257
TTCTTTAGGG CAGGAACAGT TTATTATTAC 30
<201> 258
<211> 30
<212> DNA
<213>Artificial sequence
<400> 258
ACCTGCCATT ACTATCCTTA TTTTACAGAT 30
<201> 259
<211> 30
<212> DNA
<213>Artificial sequence
<400> 259
AATGAGTTAA TTCGAGTGAC TTCATGTGGT 30
<201> 260
<211> 30
<212> DNA
<213>Artificial sequence
<400> 260
CCCGTCGGCA CCTCCCTGGG GCCTTCTTTA 30
<201> 261
<211> 30
<212> DNA
<213>Artificial sequence
<400> 261
GTACAAAGGT GGTCAGTGAG AAAGGACATT 30
<201> 262
<211> 30
<212> DNA
<213>Artificial sequence
<400> 262
TTTATAATAG AGTTTGCTAA GTACATTTTC 30
<201> 263
<211> 30
<212> DNA
<213>Artificial sequence
<400> 263
AAAAAATTAT GTCTGGACCA AATTTTTGAG 30
<201> 264
<211> 30
<212> DNA
<213>Artificial sequence
<400> 264
AGTTTGCTCA TATAAAATGA AGGTAGGAAT 30
<201> 265
<211> 30
<212> DNA
<213>Artificial sequence
<400> 265
TGAACCATAG TCTCTTACTC CATCCTTACC 30
<201> 266
<211> 30
<212> DNA
<213>Artificial sequence
<400> 266
TGGGTGAGTT TAAAAATGAT ATTGCCACAT 30
<201> 267
<211> 30
<212> DNA
<213>Artificial sequence
<400> 267
ATACCCTGGC AGGTACTTTC TTCCCCTAGC 30
<201> 268
<211> 30
<212> DNA
<213>Artificial sequence
<400> 268
AATTTTTATT CTTTGATACA TGTTGAGTAA 30
<201> 269
<211> 30
<212> DNA
<213>Artificial sequence
<400> 269
TAGCATACAA AATCGACCCT TAGTAAGTAG 30
<201> 270
<211> 30
<212> DNA
<213>Artificial sequence
<400> 270
TAAATAATAA AGCTTGGAGA ATGTGGGCAT 30
<201> 271
<211> 30
<212> DNA
<213>Artificial sequence
<400> 271
CAACCGGAAT TCACTTATGG CACTCCCAGT 30
<201> 272
<211> 30
<212> DNA
<213>Artificial sequence
<400> 272
GGGTCTCTAA GGAAAGTTGA ATAATGCCAG 30
<201> 273
<211> 30
<212> DNA
<213>Artificial sequence
<400> 273
GCCAGAGTAT ACCGATTTTC CAGGTACAGT 30
<201> 274
<211> 30
<212> DNA
<213>Artificial sequence
<400> 274
GCAAAACGGG TGAATATTAA CTGAGGGGAG 30
<201> 275
<211> 30
<212> DNA
<213>Artificial sequence
<400> 275
AAAAATACAA AAAATTAGCC GGGCGCGGTG 30
<201> 276
<211> 30
<212> DNA
<213>Artificial sequence
<400> 276
AAAAATACAA AAAATTAGCC GGGCGCGGTG 30
<201> 277
<211> 30
<212> DNA
<213>Artificial sequence
<400> 277
TATGTTATTT CATTCCTAAT CAAGTCATGA 30
<201> 278
<211> 30
<212> DNA
<213>Artificial sequence
<400> 278
AAAAACACAT GATTATCTCA ACAGATGCAG 30
<201> 279
<211> 30
<212> DNA
<213>Artificial sequence
<400> 279
TAATTTTATT TATTTAGAAT ATAACATTTA 30
<201> 280
<211> 30
<212> DNA
<213>Artificial sequence
<400> 280
TGAGCATGCA CACAGACACC AGCACATGCA 30
<201> 281
<211> 30
<212> DNA
<213>Artificial sequence
<400> 281
GCCTCTTGAA TGCCCTGACC TCACCCAGCA 30
<201> 282
<211> 30
<212> DNA
<213>Artificial sequence
<400> 282
TTCATGTCTC ACATCCAGGG CACACTGATG 30
<201> 283
<211> 30
<212> DNA
<213>Artificial sequence
<400> 283
TTAAAAGGGA CAAAGGTCAC ATAGCGAAGT 30
<201> 284
<211> 30
<212> DNA
<213>Artificial sequence
<400> 284
AATTATTTAA AAATATGGCT CTATGGCTGG 30
<201> 285
<211> 30
<212> DNA
<213>Artificial sequence
<400> 285
CTTTTCCTGT TCAAGGTTAA AATTCCTATG 30
<201> 286
<211> 30
<212> DNA
<213>Artificial sequence
<400> 286
TTGTTTCCTC CCAGATAGAA AGGGCTTGGG 30
<201> 287
<211> 30
<212> DNA
<213>Artificial sequence
<400> 287
AAGGAAAGGC CCACAGCTGG TGAGACTGCC 30
<201> 288
<211> 30
<212> DNA
<213>Artificial sequence
<400> 288
ATTCCATCAG ATATGGTTTG GATTTGTGTC 30
<201> 289
<211> 30
<212> DNA
<213>Artificial sequence
<400> 289
CCGTCTCTAC TAAAAATAAA CAAATTAGCC 30
<201> 290
<211> 30
<212> DNA
<213>Artificial sequence
<400> 290
TTTTTCAGAG TACTTCAATC TTATGGCACC 30
<201> 291
<211> 30
<212> DNA
<213>Artificial sequence
<400> 291
ATGATTTAGT CCGTAGATGT AGTGTTTAGA 30
<201> 292
<211> 30
<212> DNA
<213>Artificial sequence
<400> 292
ATCCTCCCAC CTCAGCCTCC TGAGTAGCTG 30
<201> 293
<211> 30
<212> DNA
<213>Artificial sequence
<400> 293
TGAACCTGGT AAGAGGAGGT TGCAGTGAGC 30
<201> 294
<211> 30
<212> DNA
<213>Artificial sequence
<400> 294
CACACACATG CTTTTCACCA GCAAAACGCC 30
<201> 295
<211> 30
<212> DNA
<213>Artificial sequence
<400> 295
TTCTCCTGCC AAGCTATTGT GGAGCCTCAC 30
<201> 296
<211> 30
<212> DNA
<213>Artificial sequence
<400> 296
GCCCCCTCAT CGTGTCCCCA TCTCTCTTTC 30
<201> 297
<211> 30
<212> DNA
<213>Artificial sequence
<400> 297
TGCCTATTTT GAACAGTCAG ATAGATCTTA 30
<201> 298
<211> 30
<212> DNA
<213>Artificial sequence
<400> 298
ATAAGGAGGG GAAATTTAGA CACAGAGACA 30
<201> 299
<211> 30
<212> DNA
<213>Artificial sequence
<400> 299
GACTATAATG TGTTTACTGG GATTAATTTA 30
<201> 300
<211> 30
<212> DNA
<213>Artificial sequence
<400> 300
ACTTAAACGT TAGACCTAAA ACCATAAAAA 30
<201> 301
<211> 30
<212> DNA
<213>Artificial sequence
<400> 301
GGAGAGGAGG CGCCTTGGTT CGTGGATCAG 30
<201> 302
<211> 30
<212> DNA
<213>Artificial sequence
<400> 302
TTGCCTCCAT AACTGTTGTG GGTATTGATG 30
<201> 303
<211> 30
<212> DNA
<213>Artificial sequence
<400> 303
TCAAATAACA CCACAGTGTC ATTATCTCAT 30
<201> 304
<211> 30
<212> DNA
<213>Artificial sequence
<400> 304
AATCTCACCT CACTGCAGCC TCTGCCTCCC 30
<201> 305
<211> 30
<212> DNA
<213>Artificial sequence
<400> 305
TATCAAAGGC TATTGATGTC AAGCTAAGAA 30
<201> 306
<211> 30
<212> DNA
<213>Artificial sequence
<400> 306
TGCGTGCCTC TAATCCCAGC TACTCAGGGG 30
<201> 307
<211> 30
<212> DNA
<213>Artificial sequence
<400> 307
GTGGTGCATG CCTGTAATCC CAGCTACTTG 30
<201> 308
<211> 30
<212> DNA
<213>Artificial sequence
<400> 308
GCTACTGCAC TCCAGCATGG GCGACAGAGC 30
<201> 309
<211> 30
<212> DNA
<213>Artificial sequence
<400> 309
TTTCCATACA TCTTCTGAAA TCTAGGCAGA 30
<201> 310
<211> 30
<212> DNA
<213>Artificial sequence
<400> 310
GAGGCTGAGA CAAGAGAATC GCTTGAACCC 30
<201> 311
<211> 30
<212> DNA
<213>Artificial sequence
<400> 311
TAGAAATAAC AGGGCGGGCA TGGTGGCTCA 30
<201> 312
<211> 30
<212> DNA
<213>Artificial sequence
<400> 312
CGTGCAGGTT TGTTACATAT GTATATATGT 30
<201> 313
<211> 30
<212> DNA
<213>Artificial sequence
<400> 313
CAGTCTGGGT GATGGAGTGA GACTGTCTCA 30
<201> 314
<211> 30
<212> DNA
<213>Artificial sequence
<400> 314
TGTTCAAATC TGAGGGTCAT GGAGCTGGAG 30
<201> 315
<211> 30
<212> DNA
<213>Artificial sequence
<400> 315
AGTTCCAGGA AACTCCACTT ACTCTACCAG 30
<201> 316
<211> 30
<212> DNA
<213>Artificial sequence
<400> 316
AGTTCCAGGA AACTCCACTT ACTCTACCAG 30
<201> 317
<211> 30
<212> DNA
<213>Artificial sequence
<400> 317
GCCTCCGGAG TAGCTGGGAC TACAGGCGCC 30
<201> 318
<211> 30
<212> DNA
<213>Artificial sequence
<400> 318
AACACTGACT TGAACTCTAT GATGCCACAA 30
<201> 319
<211> 30
<212> DNA
<213>Artificial sequence
<400> 319
TGGACGCCTA GCTGAGTGAT ACAACCTGAT 30
<201> 320
<211> 30
<212> DNA
<213>Artificial sequence
<400> 320
ATATTCACAC CATGGGCTGA CATATGAACC 30
<201> 321
<211> 30
<212> DNA
<213>Artificial sequence
<400> 321
CTCCTGATTT GCCTGACAGT GCCATGAAGA 30
<201> 322
<211> 30
<212> DNA
<213>Artificial sequence
<400> 322
CACCGCCCAC TGCAGCACAC ATATTGACGT 30
<201> 323
<211> 30
<212> DNA
<213>Artificial sequence
<400> 323
CCAGTAGACT CTAAGCTTCC GGAGGGCAGG 30
<201> 324
<211> 30
<212> DNA
<213>Artificial sequence
<400> 324
ATATTATTTT TATTTGTTAT GTGTGCAAAC 30
<201> 325
<211> 30
<212> DNA
<213>Artificial sequence
<400> 325
TTTATTATAA CTCAGATTTA AAGTTACAGC 30
<201> 326
<211> 30
<212> DNA
<213>Artificial sequence
<400> 326
AATGGCACAA TCTCGGCGCA CCACAACCTC 30
<201> 327
<211> 30
<212> DNA
<213>Artificial sequence
<400> 327
CTGTTCATGA TTCAGGTCCC CAGAGGAGGA 30
<201> 328
<211> 30
<212> DNA
<213>Artificial sequence
<400> 328
AAGTGGCCCA CCGCAGCCAG CCCATCCGAA 30
<201> 329
<211> 30
<212> DNA
<213>Artificial sequence
<400> 329
AAAAATCCTC AACAAAATTA CTAGTAAACC 30
<201> 330
<211> 30
<212> DNA
<213>Artificial sequence
<400> 330
AGTCAATTAG TTATATTTTT AGTTCTTTGA 30
<201> 331
<211> 30
<212> DNA
<213>Artificial sequence
<400> 331
GGCCAACTCC CATAATAAAT ACCCTCTTAC 30
<201> 332
<211> 30
<212> DNA
<213>Artificial sequence
<400> 332
GGTGATCAGT GCAGAGATAT GTCACAATGT 30
<201> 333
<211> 30
<212> DNA
<213>Artificial sequence
<400> 333
GCTTCAAAAC TCATAAACAA AATTGGATAC 30
<201> 334
<211> 30
<212> DNA
<213>Artificial sequence
<400> 334
CAGGGACCCA CTTGAGGAGG CAGTCTGCCG 30
<201> 335
<211> 30
<212> DNA
<213>Artificial sequence
<400> 335
AGGGGGATCT ATAATAATTT ATTAACAAAC 30
<201> 336
<211> 30
<212> DNA
<213>Artificial sequence
<400> 336
TTCTTTTTAA ATCTGTGTTC TCTTTATATC 30
<201> 337
<211> 30
<212> DNA
<213>Artificial sequence
<400> 337
TTCTTTTTAA ATCTGTGTTC TCTTTATATC 30
<201> 338
<211> 30
<212> DNA
<213>Artificial sequence
<400> 338
TATTTTTGTT TTTAAGAAAC TTTCTCCTAG 30
<201> 339
<211> 30
<212> DNA
<213>Artificial sequence
<400> 339
ACCATGCCTG GCTATTTTTA TACAGATGAG 30
<201> 340
<211> 30
<212> DNA
<213>Artificial sequence
<400> 340
TTAACTATAA GACATGAAAT TATAGAAGTC 30
<201> 341
<211> 30
<212> DNA
<213>Artificial sequence
<400> 341
AAATATGGAC ATTCTGGCCT AGGACCCTTC 30
<201> 342
<211> 30
<212> DNA
<213>Artificial sequence
<400> 342
AACTATCACA AGAACAAAAA ACCAAACACC 30
<201> 343
<211> 30
<212> DNA
<213>Artificial sequence
<400> 343
AGAGCCTTCA AAGGCGGCTG CCAGGAGAGA 30
<201> 344
<211> 30
<212> DNA
<213>Artificial sequence
<400> 344
CAAATGGAGA TTTTTGCATC AGGTGACACA 30
<201> 345
<211> 30
<212> DNA
<213>Artificial sequence
<400> 345
TTTCCTTTCC CTGAGTGTTT CTAGCAGTGT 30
<201> 346
<211> 30
<212> DNA
<213>Artificial sequence
<400> 346
CACAACACAC TTGCACTATT AAGAGACCCC 30
<201> 347
<211> 30
<212> DNA
<213>Artificial sequence
<400> 347
TGTCCTCCGA GCCAGTACCC CTTCTCTACC 30
<201> 348
<211> 30
<212> DNA
<213>Artificial sequence
<400> 348
ACTTCCCTCA CGATGGAGAG CCTGGGATGT 30
<201> 349
<211> 30
<212> DNA
<213>Artificial sequence
<400> 349
TTACAGATGA GGAAACTGAG ACCCAGAGAG 30
<201> 350
<211> 30
<212> DNA
<213>Artificial sequence
<400> 350
TTTGCTAACA GAGAAGAACT TAAGTATTCT 30
<201> 351
<211> 30
<212> DNA
<213>Artificial sequence
<400> 351
CAAAATTCTA GACAGGCAGT TATTATTATC 30
<201> 352
<211> 30
<212> DNA
<213>Artificial sequence
<400> 352
CAAAAAAGGA CCAACTCCAG GTGGATGATG 30
<201> 353
<211> 30
<212> DNA
<213>Artificial sequence
<400> 353
CCTAGCATCT GACAGCTCCT CGGAAAGGGT 30
<201> 354
<211> 30
<212> DNA
<213>Artificial sequence
<400> 354
GAAACCAGTT TGACCAGCAT CCTTCCCCTC 30
<201> 355
<211> 30
<212> DNA
<213>Artificial sequence
<400> 355
TTGACAGAGG AGTGAACGTT AAATCCCTAG 30
<201> 356
<211> 30
<212> DNA
<213>Artificial sequence
<400> 356
AAAATGTGTC TAAGTTGGTT AAAGATGGAA 30
<201> 357
<211> 30
<212> DNA
<213>Artificial sequence
<400> 357
TCAGACCAAG ACAGAGTTGA GAGGAGCCCC 30
<201> 358
<211> 30
<212> DNA
<213>Artificial sequence
<400> 358
GGTGTGTTTG GTGAGTTAAC AAGTAATCTT 30
<201> 359
<211> 30
<212> DNA
<213>Artificial sequence
<400> 359
TGGGAGGGTG GGGAGAGAGG CAACCAGGCT 30
<201> 360
<211> 30
<212> DNA
<213>Artificial sequence
<400> 360
GGTTGTCCAA GTTTGAGGGG AATGCTGGAA 30
<201> 361
<211> 30
<212> DNA
<213>Artificial sequence
<400> 361
AACAGGAGAA AAGGCATGCG TTTATTTTAA 30
<201> 362
<211> 30
<212> DNA
<213>Artificial sequence
<400> 362
GCTGGCTAAT TTTGGTATTT TTAGTAAAGA 30
<201> 363
<211> 30
<212> DNA
<213>Artificial sequence
<400> 363
ACAGATAGTG TTTTTCTGTT TTTCTTCATG 30
<201> 364
<211> 30
<212> DNA
<213>Artificial sequence
<400> 364
CTGGGAGAGA GGAAGCTGCC GCTTAAGTGC 30
<201> 365
<211> 30
<212> DNA
<213>Artificial sequence
<400> 365
ACCCCTTTGC CACTTGGATC CATTTCTCCA 30
<201> 366
<211> 30
<212> DNA
<213>Artificial sequence
<400> 366
AAAACACAGG TTGGCAAATA CACATGAACA 30
<201> 367
<211> 30
<212> DNA
<213>Artificial sequence
<400> 367
AGTGGAAGAT CACCGTGAAG ATATGGTCAG 30
<201> 368
<211> 30
<212> DNA
<213>Artificial sequence
<400> 368
GAATCCACTC ATAACACTCA CATCATCACT 30
<201> 369
<211> 30
<212> DNA
<213>Artificial sequence
<400> 369
TAGTAGTCAT GTAGCTAGTA AGTGGTGGTT 30
<201> 370
<211> 30
<212> DNA
<213>Artificial sequence
<400> 370
TGGAGAGATT AGGGCCATGG GGGGCAGGAG 30
<201> 371
<211> 30
<212> DNA
<213>Artificial sequence
<400> 371
AAATTATATT TTTGCTCTTA TTGTTGTTCA 30
<201> 372
<211> 30
<212> DNA
<213>Artificial sequence
<400> 372
CATGGCATCA ATGTGGGGGT AAGAGGGAGG 30
<201> 373
<211> 30
<212> DNA
<213>Artificial sequence
<400> 373
CATCCCATCC CCTTCATTTA GCTGACCACT 30
<201> 374
<211> 30
<212> DNA
<213>Artificial sequence
<400> 374
CCTCTTAAAG TGCTGATAAT CTAACAACAC 30
<201> 375
<211> 30
<212> DNA
<213>Artificial sequence
<400> 375
TCCTTTAGCT TTGTCTGAAT CCTCTCTCCT 30
<201> 376
<211> 30
<212> DNA
<213>Artificial sequence
<400> 376
CGAAGCAGAA AGCGGGGGGC AGCGCAGACC 30
<201> 377
<211> 30
<212> DNA
<213>Artificial sequence
<400> 377
TACCTATTGG CAGAATAATG AACACTTAGA 30
<201> 378
<211> 30
<212> DNA
<213>Artificial sequence
<400> 378
GCAACCAGTT CTTAAGTCTC TTTCCTCGGC 30
<201> 379
<211> 30
<212> DNA
<213>Artificial sequence
<400> 379
CTGTTTTTGT TCTCGGCATC CTCAGACAAA 30
<201> 380
<211> 30
<212> DNA
<213>Artificial sequence
<400> 380
GTGAACTGGA ATCAGGTCAG AAACAGATCC 30
<201> 381
<211> 30
<212> DNA
<213>Artificial sequence
<400> 381
TTTACTTCTT TGACAAACCT AACTCTTAAG 30
<201> 382
<211> 30
<212> DNA
<213>Artificial sequence
<400> 382
CTGACAACAC CAAGTTCAAA TGCAGGTTCA 30
<201> 383
<211> 30
<212> DNA
<213>Artificial sequence
<400> 383
TATATTTGAG GAACGACTGA TGCCATTTTC 30
<201> 384
<211> 30
<212> DNA
<213>Artificial sequence
<400> 384
ATATTTTAGA GAATAATGGA GGAAAACGTC 30
<201> 385
<211> 30
<212> DNA
<213>Artificial sequence
<400> 385
TTACTTATGA ATAAAATAAT GTGACGAACC 30
<201> 386
<211> 30
<212> DNA
<213>Artificial sequence
<400> 386
GATGGCAGCG ATGGGAGATG GAGGAGATGC 30
<201> 387
<211> 30
<212> DNA
<213>Artificial sequence
<400> 387
TATATACCCA AATGATTATA GATCATTCTA 30
<201> 388
<211> 30
<212> DNA
<213>Artificial sequence
<400> 388
TTTTCATTGA CTACATGTTA AAATAACCGT 30
<201> 389
<211> 30
<212> DNA
<213>Artificial sequence
<400> 389
GTCCAATGCA GAAACAGTTA AGGTTTTACA 30
<201> 390
<211> 30
<212> DNA
<213>Artificial sequence
<400> 390
TGGATGAAAA TATGAATGGA TGGCTAAGAA 30
<201> 391
<211> 30
<212> DNA
<213>Artificial sequence
<400> 391
AAGATAGACA CAAGGTGAGT TGACTATTAT 30
<201> 392
<211> 30
<212> DNA
<213>Artificial sequence
<400> 392
TAATACAAAT GTAGTTCTCT ATTTCTTTAA 30
<201> 393
<211> 30
<212> DNA
<213>Artificial sequence
<400> 393
CCTGGACGAC AGAGCAAGAT CCTGTGTCAA 30
<201> 394
<211> 30
<212> DNA
<213>Artificial sequence
<400> 394
AGTCATTTGG TTTCATTGAG ACATGCCTGC 30
<201> 395
<211> 30
<212> DNA
<213>Artificial sequence
<400> 395
ATTTTTACTA CTCTGCTGTG AAACTCACCC 30
<201> 396
<211> 30
<212> DNA
<213>Artificial sequence
<400> 396
CATGGAGAGC CCACACCAAC CACCAGATAT 30
<201> 397
<211> 30
<212> DNA
<213>Artificial sequence
<400> 397
CCAGGCTGGA GTGCAGTGGC ATGATCACAA 30
<201> 398
<211> 30
<212> DNA
<213>Artificial sequence
<400> 398
GCCCGACCTT CTCCCACACA CTCTACACAT 30
<201> 399
<211> 30
<212> DNA
<213>Artificial sequence
<400> 399
TTAAGACATA AATTCTGAAT GTTATCTAAT 30
<201> 400
<211> 30
<212> DNA
<213>Artificial sequence
<400> 400
CCTAATTTTG AGACCTGTTC ACATCCGGGA 30
<201> 401
<211> 30
<212> DNA
<213>Artificial sequence
<400> 401
TGGGAGGCCG AGGCAGACAG ATCACCTGGG 30
<201> 402
<211> 30
<212> DNA
<213>Artificial sequence
<400> 402
ATAGTGAATC CATGACTTCC AAAATCAAGT 30
<201> 403
<211> 30
<212> DNA
<213>Artificial sequence
<400> 403
TGACATTCCT AATGTGGGAT TTCTTTTTAG 30
<201> 404
<211> 30
<212> DNA
<213>Artificial sequence
<400> 404
TACAAACTGG CAGTCATGTA GGATGAGTAA 30
<201> 405
<211> 30
<212> DNA
<213>Artificial sequence
<400> 405
GTGAATCGCT TGAGCCCAGG AGTTGCAGCC 30
<201> 406
<211> 30
<212> DNA
<213>Artificial sequence
<400> 406
TTGGACAATT AACACAGCTG GGGTACAGGG 30
<201> 407
<211> 30
<212> DNA
<213>Artificial sequence
<400> 407
AGTCGCAACA GTGAGAAGAA AAGAAGAGAG 30
<201> 408
<211> 30
<212> DNA
<213>Artificial sequence
<400> 408
ATTGACTATG GAAATAAATG GTATTCTCAT 30
<201> 409
<211> 30
<212> DNA
<213>Artificial sequence
<400> 409
CAAAAATTAA CTGGGTGTGG TAGCAGGTGC 30
<201> 410
<211> 30
<212> DNA
<213>Artificial sequence
<400> 410
CTCCTGCCTC AGTATCAAGA GTAGCTGGGA 30
<201> 411
<211> 30
<212> DNA
<213>Artificial sequence
<400> 411
AAACACACTC TTTGAGGCTA AAGCAAATCT 30
<201> 412
<211> 30
<212> DNA
<213>Artificial sequence
<400> 412
AACAATGAGG CCTGGATTGA TTGATTGATT 30
<201> 413
<211> 30
<212> DNA
<213>Artificial sequence
<400> 413
GAATGCAATA AGTGTCCAGT GAGTTATTTG 30
<201> 414
<211> 30
<212> DNA
<213>Artificial sequence
<400> 414
CTCTTTTGTA AATTATTATT CAGGTTTTAG 30
<201> 415
<211> 30
<212> DNA
<213>Artificial sequence
<400> 415
TCCAGCCCAG CCCATCACCC TTCCTAAGGC 30
<201> 416
<211> 30
<212> DNA
<213>Artificial sequence
<400> 416
ATGCTAAAGA TATAGGGAAA TAAGTCCTAA 30
<201> 417
<211> 30
<212> DNA
<213>Artificial sequence
<400> 417
CACTAGGTAC AGTCTGTGTG GCATCTGTGG 30
<201> 418
<211> 30
<212> DNA
<213>Artificial sequence
<400> 418
TGGGCCTCAG TTTTTTAATC TGTAAAATGG 30
<201> 419
<211> 30
<212> DNA
<213>Artificial sequence
<400> 419
TGACTGACTT TAAAGATATG ACTTGTATAA 30
<201> 420
<211> 30
<212> DNA
<213>Artificial sequence
<400> 420
TCCCTTCTCC ATTCCCAGGG CTGAGTAGTG 30
<201> 421
<211> 30
<212> DNA
<213>Artificial sequence
<400> 421
CAGTATATCT CTTTACTACA TGGTTTATGG 30
<201> 422
<211> 30
<212> DNA
<213>Artificial sequence
<400> 422
AGGGAAAACT CACTGAAATA TTTGAAACTA 30
<201> 423
<211> 30
<212> DNA
<213>Artificial sequence
<400> 423
ATTTCAAGTA TAATGTGTCA TGAGCTGAGA 30
<201> 424
<211> 30
<212> DNA
<213>Artificial sequence
<400> 424
AAGACCACCA TTTGTTGAGT ATCCATTGTT 30
<201> 425
<211> 30
<212> DNA
<213>Artificial sequence
<400> 425
CCTGATTAGC TGCACTGGAA CATAGAACAT 30
<201> 426
<211> 30
<212> DNA
<213>Artificial sequence
<400> 426
TTGGGAGCAA CTGTGGGCAA AGGGAGGCCA 30
<201> 427
<211> 30
<212> DNA
<213>Artificial sequence
<400> 427
GCCCAAGAGA ACCTCTAAGA TTCCTTTTTT 30
<201> 428
<211> 30
<212> DNA
<213>Artificial sequence
<400> 428
TCGGCTGCCC AAAGTGTTGG GATTACAGGC 30
<201> 429
<211> 30
<212> DNA
<213>Artificial sequence
<400> 429
AGCAGAATTC CTCCATCCCA GGAAAACCTC 30
<201> 430
<211> 30
<212> DNA
<213>Artificial sequence
<400> 430
TTGTTTTTAA TTCTGTTTAT GTGGTGTATC 30
<201> 431
<211> 30
<212> DNA
<213>Artificial sequence
<400> 431
TTAGGGGAGA GACCTGTTGG GAAAAACAAG 30
<201> 432
<211> 30
<212> DNA
<213>Artificial sequence
<400> 432
CCCTCAAACT TCAACTGACA CACAGGATCC 30
<201> 433
<211> 30
<212> DNA
<213>Artificial sequence
<400> 433
ATAAATTCAC TTTTAAATAT TCAATTTTAA 30
<201> 434
<211> 30
<212> DNA
<213>Artificial sequence
<400> 434
GACCCTCTGT TACCTAAATT TTCTCCTTAT 30
<201> 435
<211> 30
<212> DNA
<213>Artificial sequence
<400> 435
CAGCCCCTGC CTGGCCACCC CACCGCTTAC 30
<201> 436
<211> 30
<212> DNA
<213>Artificial sequence
<400> 436
AATGGTATTG CAAGAGGGTG ATCCCCCTGT 30
<201> 437
<211> 30
<212> DNA
<213>Artificial sequence
<400> 437
CCTCCGCCTC CTGAGTTCAA GCCATTCTTG 30
<201> 438
<211> 30
<212> DNA
<213>Artificial sequence
<400> 438
CCAGTGTCGC ATCCTTGGGC CTCCTTGGAT 30
<201> 439
<211> 30
<212> DNA
<213>Artificial sequence
<400> 439
TAACAGTCAG GTCGCTCAGC TGCAGGTCCG 30
<201> 440
<211> 30
<212> DNA
<213>Artificial sequence
<400> 440
GGGACTACAG GTGCCCCCAC CACATCTGGC 30
<201> 441
<211> 30
<212> DNA
<213>Artificial sequence
<400> 441
ATTTAATGCT GTCTATCACC AAAAACCATT 30
<201> 442
<211> 30
<212> DNA
<213>Artificial sequence
<400> 442
GGAAAGAGAC AGCCTATGGG ATGAGACAAC 30
<201> 443
<211> 30
<212> DNA
<213>Artificial sequence
<400> 443
GAAGTCAGGT GGAAGTGTAG AGATGGGCTA 30
<201> 444
<211> 30
<212> DNA
<213>Artificial sequence
<400> 444
CCTCTCTTGT CCCATTTACT ATTTTTATGC 30
<201> 445
<211> 30
<212> DNA
<213>Artificial sequence
<400> 445
TAGCAAGAGG GACTTTCTGA GGATTAAAAA 30
<201> 446
<211> 30
<212> DNA
<213>Artificial sequence
<400> 446
TGCATGAGGT TCTCAATTAT ATAAATTTAT 30
<201> 447
<211> 30
<212> DNA
<213>Artificial sequence
<400> 447
TGCATGAGGT TCTCAATTAT ATAAATTTAT 30
<201> 448
<211> 30
<212> DNA
<213>Artificial sequence
<400> 448
CTATTGAAAA ATTCTGCCGG CTGATCCCAG 30
<201> 449
<211> 30
<212> DNA
<213>Artificial sequence
<400> 449
TTAATGGTTC AAAAGATCAT AAGCTCTCCA 30
<201> 450
<211> 30
<212> DNA
<213>Artificial sequence
<400> 450
GAACCAGGGA GGCGGGGCTT GCAGTGAGCC 30
<201> 451
<211> 30
<212> DNA
<213>Artificial sequence
<400> 451
GGGTCTCCCA AAGTGCTAGG ATTACAGGTG 30
<201> 452
<211> 30
<212> DNA
<213>Artificial sequence
<400> 452
CATATTAAGT CTATTCTTGG GTCTTTTTAA 30
<201> 453
<211> 30
<212> DNA
<213>Artificial sequence
<400> 453
CCTCCCGGCT TCAAGTGATT CTCCTGCCTC 30
<201> 454
<211> 30
<212> DNA
<213>Artificial sequence
<400> 454
CACCACGCCT GGCTAACTTT TTTGTATTTT 30
<201> 455
<211> 30
<212> DNA
<213>Artificial sequence
<400> 455
TAACAAGAAG AGCTAACTAT CCTAAATATA 30
<201> 456
<211> 30
<212> DNA
<213>Artificial sequence
<400> 456
ACTAAAATAC AGATGGTTCC ACATCTTCTA 30
<201> 457
<211> 30
<212> DNA
<213>Artificial sequence
<400> 457
GTTGGAAGTG GGTTTCTGAG GTTGTGTTCC 30
<201> 458
<211> 30
<212> DNA
<213>Artificial sequence
<400> 458
CTTCCTCTTT TCCTATTTGA ATACACTTTC 30
<201> 459
<211> 30
<212> DNA
<213>Artificial sequence
<400> 459
CATCCAGGGA TCATCCTGTA CCTCAGACTC 30
<201> 460
<211> 30
<212> DNA
<213>Artificial sequence
<400> 460
CCAATTTTGG TACCAGGGAA ATGTTGCAAC 30
<201> 461
<211> 30
<212> DNA
<213>Artificial sequence
<400> 461
CAGGCCATAA ATAGCCCTAA TCTCTATCCC 30
<201> 462
<211> 30
<212> DNA
<213>Artificial sequence
<400> 462
TTTCTTCCCT TTCTATATAC CACAAAAAGT 30
<201> 463
<211> 30
<212> DNA
<213>Artificial sequence
<400> 463
ATAATGCGGC ATTTTACATT CACACAGCAG 30
<201> 464
<211> 30
<212> DNA
<213>Artificial sequence
<400> 464
TGCCATGTTG GTGTGCTGCA CCCATTAACT 30
<201> 465
<211> 30
<212> DNA
<213>Artificial sequence
<400> 465
TAATTGAAGG AAAGATAAAC ATGAGATAGA 30
<201> 466
<211> 30
<212> DNA
<213>Artificial sequence
<400> 466
AAAAAATCAT TTTTAAAATC TGAATTACAT 30
<201> 467
<211> 30
<212> DNA
<213>Artificial sequence
<400> 467
GCGTGAACCT GGGAGGCGGA GCTTGCAGTG 30
<201> 468
<211> 30
<212> DNA
<213>Artificial sequence
<400> 468
CCTGACGTCC CTGCTAAAGA ATCAACTTCC 30
<201> 469
<211> 30
<212> DNA
<213>Artificial sequence
<400> 469
CTCTTTTGGA CTCCTCTTCT GGCCTTGCCT 30
<201> 470
<211> 30
<212> DNA
<213>Artificial sequence
<400> 470
CTCTTTTGGA CTCCTCTTCT GGCCTTGCCT 30
<201> 471
<211> 30
<212> DNA
<213>Artificial sequence
<400> 471
TGTGTGTGTG TGTGTGTGTG TGTGTGTGTG 30
<201> 472
<211> 30
<212> DNA
<213>Artificial sequence
<400> 472
TCACAATAAT TGAAAAATAA AAAATGGACA 30
<201> 473
<211> 30
<212> DNA
<213>Artificial sequence
<400> 473
ATGTAAATGT ATGCATGCTT TTATCCGATA 30
<201> 474
<211> 30
<212> DNA
<213>Artificial sequence
<400> 474
ATGTAAATGT ATGCATGCTT TTATCCGATA 30
<201> 475
<211> 30
<212> DNA
<213>Artificial sequence
<400> 475
ATGTAAATGT ATGCATGCTT TTATCCGATA 30
<201> 476
<211> 30
<212> DNA
<213>Artificial sequence
<400> 476
CCTGGCCTCA AGCAGTCCTC CTGACTCAGC 30
<201> 477
<211> 30
<212> DNA
<213>Artificial sequence
<400> 477
AGAGAGAGAG AGAGAGAGAG TAAAAAGGAG 30
<201> 478
<211> 30
<212> DNA
<213>Artificial sequence
<400> 478
TGCTATATGG TCTCATTTAT ATGTGGAAAT 30
<201> 479
<211> 30
<212> DNA
<213>Artificial sequence
<400> 479
AAGGTGCAAT GAAGAAAAAT TCTAAGTAGC 30
<201> 480
<211> 30
<212> DNA
<213>Artificial sequence
<400> 480
GTTCTGCATC CTTCTTTAAA TCATCCACAA 30
<201> 481
<211> 30
<212> DNA
<213>Artificial sequence
<400> 481
TCTGCCATCT AGTCAGGTCC TAGGTTCCCT 30
<201> 482
<211> 30
<212> DNA
<213>Artificial sequence
<400> 482
TGCAGAATAT ATGATCAATG TACCAACACA 30
<201> 483
<211> 30
<212> DNA
<213>Artificial sequence
<400> 483
ATTGTCAAAT TAATTTAAAT AGCAGCAAAA 30
<201> 484
<211> 30
<212> DNA
<213>Artificial sequence
<400> 484
CTTGATCTTT AAACTGAGAA AGCCTGGGAG 30
<201> 485
<211> 30
<212> DNA
<213>Artificial sequence
<400> 485
ATTTCTTCCC CTCCATAATC CTTGAAGCCT 30
<201> 486
<211> 30
<212> DNA
<213>Artificial sequence
<400> 486
AATTGTAACT TTTAATAACC TAAATTCATA 30
<201> 487
<211> 30
<212> DNA
<213>Artificial sequence
<400> 487
ATAGATAAGG TCACACACTA CATGTTGTTG 30
<201> 488
<211> 30
<212> DNA
<213>Artificial sequence
<400> 488
TCCTCAGTTT GGGCAGTATG GGAAATTACA 30
<201> 489
<211> 30
<212> DNA
<213>Artificial sequence
<400> 489
CCATAAATTA ATGTTGCTTC CTTTTCCCAC 30
<201> 490
<211> 30
<212> DNA
<213>Artificial sequence
<400> 490
CAAATACTGT TTTTATAACT CCCACCTTTA 30
<201> 491
<211> 30
<212> DNA
<213>Artificial sequence
<400> 491
GGAGAGGTTC TGACTCACCC AAGGGCACAC 30
<201> 492
<211> 30
<212> DNA
<213>Artificial sequence
<400> 492
TTGGACTGCC AATTCCAGCT TCCTGGCTAC 30
<201> 493
<211> 30
<212> DNA
<213>Artificial sequence
<400> 493
TTCAAAGCCC ATGCTCCTGC CATTATGCCA 30
<201> 494
<211> 30
<212> DNA
<213>Artificial sequence
<400> 494
GTGATCTTGT TCATTTCCCT GGCTTCAACT 30
<201> 495
<211> 30
<212> DNA
<213>Artificial sequence
<400> 495
GTGATCTTGT TCATTTCCCT GGCTTCAACT 30
<201> 496
<211> 30
<212> DNA
<213>Artificial sequence
<400> 496
TTGAGAATAG TAAATAAGTT AATAAAGTAA 30
<201> 497
<211> 30
<212> DNA
<213>Artificial sequence
<400> 497
TTGCATTTAC TAAAGGAGAG TACAAACAAA 30
<201> 498
<211> 30
<212> DNA
<213>Artificial sequence
<400> 498
TTTCTTTTTT GATAATGGTT TCTGCATTTC 30
<201> 499
<211> 30
<212> DNA
<213>Artificial sequence
<400> 499
TTCTCTTTCT TTTATAGAAA ACTACACAAA 30
<201> 500
<211> 30
<212> DNA
<213>Artificial sequence
<400> 500
GAAATTTACC CAACAGATAC ACTTACACAT 30
<201> 501
<211> 30
<212> DNA
<213>Artificial sequence
<400> 501
ACCATAGGCC ATGTCAGCTA GGGGTCATTT 30
<201> 502
<211> 30
<212> DNA
<213>Artificial sequence
<400> 502
AATTCCTTGC CACCTCGCTA CTTTCCCTGC 30
<201> 503
<211> 30
<212> DNA
<213>Artificial sequence
<400> 503
CAACTTCACA ACATACCCAA ACTCACCACA 30
<201> 504
<211> 30
<212> DNA
<213>Artificial sequence
<400> 504
AGGTTTAATT GACTCACAGT TCTGCATGAC 30
<201> 505
<211> 30
<212> DNA
<213>Artificial sequence
<400> 505
AATTTCCTTT ATTTGTGTTT GAGATTCCAT 30
<201> 506
<211> 30
<212> DNA
<213>Artificial sequence
<400> 506
TGACCCCCAT TGCTTGTATT CATAATCTAT 30
<201> 507
<211> 30
<212> DNA
<213>Artificial sequence
<400> 507
CTTCAGTTTC ATTCTCACAA CTTCACCACA 30
<201> 508
<211> 30
<212> DNA
<213>Artificial sequence
<400> 508
GGAGTTTGAG ACTAGCCTGG GCAACATGGC 30
<201> 509
<211> 30
<212> DNA
<213>Artificial sequence
<400> 509
TGGAGTCTCA CTCTATTGCC CAGGCTGGAG 30
<201> 510
<211> 30
<212> DNA
<213>Artificial sequence
<400> 510
AAAAGTATTT TAAGTTGACC TCATTTCATA 30
<201> 511
<211> 30
<212> DNA
<213>Artificial sequence
<400> 511
TTGTGATCCA CCCGCCTTGG CCTCCCAAAG 30
<201> 512
<211> 30
<212> DNA
<213>Artificial sequence
<400> 512
TTATTAAAAT GCTAAAGTCT TCCAGAAACA 30
<201> 513
<211> 30
<212> DNA
<213>Artificial sequence
<400> 513
AGGGCAAAAG AGGATACAAG AAAGTTCTTA 30
<201> 514
<211> 30
<212> DNA
<213>Artificial sequence
<400> 514
GTGAGACTCT GAAAACAACA AACAAACAAA 30
<201> 515
<211> 30
<212> DNA
<213>Artificial sequence
<400> 515
CTATTCCTGA CATAAAATGA TATGCTTATT 30
<201> 516
<211> 30
<212> DNA
<213>Artificial sequence
<400> 516
AGCAAGGACC CTTATTGGCA TCTTCCCACT 30
<201> 517
<211> 30
<212> DNA
<213>Artificial sequence
<400> 517
TTAAATATTT TAAATTGAAT TAAATTAGTT 30
<201> 518
<211> 30
<212> DNA
<213>Artificial sequence
<400> 518
AGGGCCTCGA CCTAACTCAA TGAAATGTCT 30
<201> 519
<211> 30
<212> DNA
<213>Artificial sequence
<400> 519
AATGCCAACT TTCTTTTCTT CTCTATAACT 30
<201> 520
<211> 30
<212> DNA
<213>Artificial sequence
<400> 520
CGATCTCCGG GGCTCACAGG ACCCTCCCTC 30
<201> 521
<211> 30
<212> DNA
<213>Artificial sequence
<400> 521
ACCTAAATAT CCATCAATAA ATATTTATCC 30
<201> 522
<211> 30
<212> DNA
<213>Artificial sequence
<400> 522
AGTGTCAGGA ACTGCTTCTG GAGAGGCCTC 30
<201> 523
<211> 30
<212> DNA
<213>Artificial sequence
<400> 523
AAAAATAGCT AGTATTTACA TTTAATGTAT 30
<201> 524
<211> 30
<212> DNA
<213>Artificial sequence
<400> 524
AAAAATAGCT AGTATTTACA TTTAATGTAA 30
<201> 525
<211> 30
<212> DNA
<213>Artificial sequence
<400> 525
AAACAATGTA ATTAAGATAG AAATTTTTTA 30
<201> 526
<211> 30
<212> DNA
<213>Artificial sequence
<400> 526
AAACAATGTA ATTAAGATAG AAATTTTTTT 30
<201> 527
<211> 30
<212> DNA
<213>Artificial sequence
<400> 527
CTCTTTTTTG GTTCTATATG AATTTTGGAA 30
<201> 528
<211> 30
<212> DNA
<213>Artificial sequence
<400> 528
CTCTTTTTTG GTTCTATATG AATTTTGGAT 30
<201> 529
<211> 30
<212> DNA
<213>Artificial sequence
<400> 529
AATCCTCTCT GAAATAGCAC CATCATAAAA 30
<201> 530
<211> 30
<212> DNA
<213>Artificial sequence
<400> 530
AATCCTCTCT GAAATAGCAC CATCATAAAT 30
<201> 531
<211> 30
<212> DNA
<213>Artificial sequence
<400> 531
GTCTATTGTG TCTACCATAA TTTTATCAGA 30
<201> 532
<211> 30
<212> DNA
<213>Artificial sequence
<400> 532
GTCTATTGTG TCTACCATAA TTTTATCAGT 30
<201> 533
<211> 30
<212> DNA
<213>Artificial sequence
<400> 533
AGAATTGCTC AAATGAGACA GAAATGAGAA 30
<201> 534
<211> 30
<212> DNA
<213>Artificial sequence
<400> 534
AGAATTGCTC AAATGAGACA GAAATGAGAT 30
<201> 535
<211> 30
<212> DNA
<213>Artificial sequence
<400> 535
GGAGATCCTG TCTCAAATAC ATATATATAT 30
<201> 536
<211> 30
<212> DNA
<213>Artificial sequence
<400> 536
GGAGATCCTG TCTCAAATAC ATATATATAA 30
<201> 537
<211> 30
<212> DNA
<213>Artificial sequence
<400> 537
GATTACTAAG ATTTTTGGTG CTTCCTTAAA 30
<201> 538
<211> 30
<212> DNA
<213>Artificial sequence
<400> 538
GATTACTAAG ATTTTTGGTG CTTCCTTAAT 30
<201> 539
<211> 30
<212> DNA
<213>Artificial sequence
<400> 539
GCCCAATATT AATGCAATAT TGTCACTGTA 30
<201> 540
<211> 30
<212> DNA
<213>Artificial sequence
<400> 540
GCCCAATATT AATGCAATAT TGTCACTGTT 30
<201> 541
<211> 30
<212> DNA
<213>Artificial sequence
<400> 541
TCTCTGATTC ATATTGTATT CATGTTAAAT 30
<201> 542
<211> 30
<212> DNA
<213>Artificial sequence
<400> 542
TCTCTGATTC ATATTGTATT CATGTTAAAA 30
<201> 543
<211> 30
<212> DNA
<213>Artificial sequence
<400> 543
GATACAGGAA TATTTTACTC TTTGAATTTA 30
<201> 544
<211> 30
<212> DNA
<213>Artificial sequence
<400> 544
GATACAGGAA TATTTTACTC TTTGAATTTT 30
<201> 545
<211> 30
<212> DNA
<213>Artificial sequence
<400> 545
TCGCTCACGA ACCATTGACA AAACTAGCCA 30
<201> 546
<211> 30
<212> DNA
<213>Artificial sequence
<400> 546
TCGCTCACGA ACCATTGACA AAACTAGCCT 30
<201> 547
<211> 30
<212> DNA
<213>Artificial sequence
<400> 547
GGATCTCTTT TTGTTACTCT AAATTAACAA 30
<201> 548
<211> 30
<212> DNA
<213>Artificial sequence
<400> 548
GGATCTCTTT TTGTTACTCT AAATTAACAT 30
<201> 549
<211> 30
<212> DNA
<213>Artificial sequence
<400> 549
TTAATAATCT TCATAACATC ATGTTTGTTA 30
<201> 550
<211> 30
<212> DNA
<213>Artificial sequence
<400> 550
TTAATAATCT TCATAACATC ATGTTTGTTT 30
<201> 551
<211> 30
<212> DNA
<213>Artificial sequence
<400> 551
TATGTATATT TTTTCATTAT TTTCTTATAA 30
<201> 552
<211> 30
<212> DNA
<213>Artificial sequence
<400> 552
TATGTATATT TTTTCATTAT TTTCTTATAT 30
<201> 553
<211> 30
<212> DNA
<213>Artificial sequence
<400> 553
TAATTTTCTT TGTGGCTATT GTAAATAGGA 30
<201> 554
<211> 30
<212> DNA
<213>Artificial sequence
<400> 554
TAATTTTCTT TGTGGCTATT GTAAATAGGT 30
<201> 555
<211> 30
<212> DNA
<213>Artificial sequence
<400> 555
GATGATTATA AGATCGACTG TTCCTATTAA 30
<201> 556
<211> 30
<212> DNA
<213>Artificial sequence
<400> 556
GATGATTATA AGATCGACTG TTCCTATTAT 30
<201> 557
<211> 30
<212> DNA
<213>Artificial sequence
<400> 557
GTGATTCTCC TACCTCAGCC TCCCTAGTAG 30
<201> 558
<211> 30
<212> DNA
<213>Artificial sequence
<400> 558
GTGATTCTCC TACCTCAGCC TCCCTAGTAC 30
<201> 559
<211> 30
<212> DNA
<213>Artificial sequence
<400> 559
ACTAGAAGCT ACATAATTTG CCAAAGACAC 30
<201> 560
<211> 30
<212> DNA
<213>Artificial sequence
<400> 560
ACTAGAAGCT ACATAATTTG CCAAAGACAG 30
<201> 561
<211> 30
<212> DNA
<213>Artificial sequence
<400> 561
CCAAACCTAC TAAATCAGAG ACTTTAAGGG 30
<201> 562
<211> 30
<212> DNA
<213>Artificial sequence
<400> 562
CCAAACCTAC TAAATCAGAG ACTTTAAGGC 30
<201> 563
<211> 30
<212> DNA
<213>Artificial sequence
<400> 563
CCACTGAGAA TTTATACTAT AGACCTATTC 30
<201> 564
<211> 30
<212> DNA
<213>Artificial sequence
<400> 564
CCACTGAGAA TTTATACTAT AGACCTATTG 30
<201> 565
<211> 30
<212> DNA
<213>Artificial sequence
<400> 565
CATTACACAC CTCCTCCCCG CTTGTCCCAG 30
<201> 566
<211> 30
<212> DNA
<213>Artificial sequence
<400> 566
CATTACACAC CTCCTCCCCG CTTGTCCCAC 30
<201> 567
<211> 30
<212> DNA
<213>Artificial sequence
<400> 567
CTAGGCACTG AGGCAAGCGT TTGCATTCTC 30
<201> 568
<211> 30
<212> DNA
<213>Artificial sequence
<400> 568
CTAGGCACTG AGGCAAGCGT TTGCATTCTG 30
<201> 569
<211> 30
<212> DNA
<213>Artificial sequence
<400> 569
CTATAGAACA ACAATCATTT ATACGATTTG 30
<201> 570
<211> 30
<212> DNA
<213>Artificial sequence
<400> 570
CTATAGAACA ACAATCATTT ATACGATTTC 30
<201> 571
<211> 30
<212> DNA
<213>Artificial sequence
<400> 571
TGCTAGAGAA AGCACAAGAC AGGAGTCAGG 30
<201> 572
<211> 30
<212> DNA
<213>Artificial sequence
<400> 572
TGCTAGAGAA AGCACAAGAC AGGAGTCAGC 30
<201> 573
<211> 30
<212> DNA
<213>Artificial sequence
<400> 573
GAGAATATGG TGGCTGGAAT GTGTCGGGTC 30
<201> 574
<211> 30
<212> DNA
<213>Artificial sequence
<400> 574
GAGAATATGG TGGCTGGAAT GTGTCGGGTG 30
<201> 575
<211> 30
<212> DNA
<213>Artificial sequence
<400> 575
CCAATTCAGT ATCAGTGTGC CTCAATCCTC 30
<201> 576
<211> 30
<212> DNA
<213>Artificial sequence
<400> 576
CCAATTCAGT ATCAGTGTGC CTCAATCCTG 30
<201> 577
<211> 30
<212> DNA
<213>Artificial sequence
<400> 577
ATTCACATCA TCCATTTTAT AAGACATGTC 30
<201> 578
<211> 30
<212> DNA
<213>Artificial sequence
<400> 578
ATTCACATCA TCCATTTTAT AAGACATGTG 30
<201> 579
<211> 30
<212> DNA
<213>Artificial sequence
<400> 579
ATCATCTCAC TACAGCTTTC TTGGTGATAG 30
<201> 580
<211> 30
<212> DNA
<213>Artificial sequence
<400> 580
ATCATCTCAC TACAGCTTTC TTGGTGATAC 30
<201> 581
<211> 30
<212> DNA
<213>Artificial sequence
<400> 581
TGCTCCCAGT AGAATATAAG CTCCTTGAGG 30
<201> 582
<211> 30
<212> DNA
<213>Artificial sequence
<400> 582
TGCTCCCAGT AGAATATAAG CTCCTTGAGC 30
<201> 583
<211> 30
<212> DNA
<213>Artificial sequence
<400> 583
GGAGATTGTA TGCCTGTCAT CCTGCATTCC 30
<201> 584
<211> 30
<212> DNA
<213>Artificial sequence
<400> 584
GGAGATTGTA TGCCTGTCAT CCTGCATTCG 30
<201> 585
<211> 30
<212> DNA
<213>Artificial sequence
<400> 585
CCAGATTCTC CATCAGCAGT GCCCAGGTGG 30
<201> 586
<211> 30
<212> DNA
<213>Artificial sequence
<400> 586
CCAGATTCTC CATCAGCAGT GCCCAGGTGC 30
<201> 587
<211> 30
<212> DNA
<213>Artificial sequence
<400> 587
ATAAGAAACA GAGGCGGTGC TCAATTCATG 30
<201> 588
<211> 30
<212> DNA
<213>Artificial sequence
<400> 588
ATAAGAAACA GAGGCGGTGC TCAATTCATC 30
<201> 589
<211> 30
<212> DNA
<213>Artificial sequence
<400> 589
TGGATGATGA CCTTCACTTA CAGCAGCTGG 30
<201> 590
<211> 30
<212> DNA
<213>Artificial sequence
<400> 590
TGGATGATGA CCTTCACTTA CAGCAGCTGC 30
<201> 591
<211> 30
<212> DNA
<213>Artificial sequence
<400> 591
GTCGTACATC TCCTTCGGGC CCAAGATCTC 30
<201> 592
<211> 30
<212> DNA
<213>Artificial sequence
<400> 592
GTCGTACATC TCCTTCGGGC CCAAGATCTG 30
<201> 593
<211> 30
<212> DNA
<213>Artificial sequence
<400> 593
GTCTCAAAAA AAAGGAAAAA AGAAAAAAAC 30
<201> 594
<211> 30
<212> DNA
<213>Artificial sequence
<400> 594
GTCTCAAAAA AAAGGAAAAA AGAAAAAAAG 30
<201> 595
<211> 30
<212> DNA
<213>Artificial sequence
<400> 595
TCTTGCCTCA GAGCCCCAAT CACCAATCTG 30
<201> 596
<211> 30
<212> DNA
<213>Artificial sequence
<400> 596
TCTTGCCTCA GAGCCCCAAT CACCAATCTC 30
<201> 597
<211> 30
<212> DNA
<213>Artificial sequence
<400> 597
CCAAGATTGT GCCATTGCAC TCCAGCCGGG 30
<201> 598
<211> 30
<212> DNA
<213>Artificial sequence
<400> 598
CCAAGATTGT GCCATTGCAC TCCAGCCGGC 30
<201> 599
<211> 30
<212> DNA
<213>Artificial sequence
<400> 599
ACGGTGAAAC CCCATCTCTA CTAAAAATGC 30
<201> 600
<211> 30
<212> DNA
<213>Artificial sequence
<400> 600
ACGGTGAAAC CCCATCTCTA CTAAAAATGG 30
<201> 601
<211> 30
<212> DNA
<213>Artificial sequence
<400> 601
TTTGCAACGT ACCCATCTGA CAAGGGATTC 30
<201> 602
<211> 30
<212> DNA
<213>Artificial sequence
<400> 602
TTTGCAACGT ACCCATCTGA CAAGGGATTG 30
<201> 603
<211> 30
<212> DNA
<213>Artificial sequence
<400> 603
ATGTTATCTT GTAAAAGTGT TGTAGGTGAG 30
<201> 604
<211> 30
<212> DNA
<213>Artificial sequence
<400> 604
ATGTTATCTT GTAAAAGTGT TGTAGGTGAC 30
<201> 605
<211> 30
<212> DNA
<213>Artificial sequence
<400> 605
TCTGCCTCCT GGGTTCAATC AGTTCTCCTG 30
<201> 606
<211> 30
<212> DNA
<213>Artificial sequence
<400> 606
TCTGCCTCCT GGGTTCAATC AGTTCTCCTC 30
<201> 607
<211> 30
<212> DNA
<213>Artificial sequence
<400> 607
GCCGTGTTCC CCAGGCTGGT CTCAAACTCC 30
<201> 608
<211> 30
<212> DNA
<213>Artificial sequence
<400> 608
GCCGTGTTCC CCAGGCTGGT CTCAAACTCG 30
<201> 609
<211> 30
<212> DNA
<213>Artificial sequence
<400> 609
GGTAGAGAAG ACAAGTGTGG TGTGTATCAG 30
<201> 610
<211> 30
<212> DNA
<213>Artificial sequence
<400> 610
GGTAGAGAAG ACAAGTGTGG TGTGTATCAC 30
<201> 611
<211> 30
<212> DNA
<213>Artificial sequence
<400> 611
GCAAACTAAC ACAGGAACAG AAAACCAAAC 30
<201> 612
<211> 30
<212> DNA
<213>Artificial sequence
<400> 612
GCAAACTAAC ACAGGAACAG AAAACCAAAG 30
<201> 613
<211> 30
<212> DNA
<213>Artificial sequence
<400> 613
AGCCTGGGCA ACACAGTGAA ACCCGCTCTC 30
<201> 614
<211> 30
<212> DNA
<213>Artificial sequence
<400> 614
AGCCTGGGCA ACACAGTGAA ACCCGCTCTG 30
<201> 615
<211> 30
<212> DNA
<213>Artificial sequence
<400> 615
TGTCTCCTCA CCTGGGAAGT ACAAGGGGTC 30
<201> 616
<211> 30
<212> DNA
<213>Artificial sequence
<400> 616
TGTCTCCTCA CCTGGGAAGT ACAAGGGGTG 30
<201> 617
<211> 30
<212> DNA
<213>Artificial sequence
<400> 617
AGGAAGGAAA TGCAGGCAAC AAGGAGAAGG 30
<201> 618
<211> 30
<212> DNA
<213>Artificial sequence
<400> 618
AGGAAGGAAA TGCAGGCAAC AAGGAGAAGC 30
<201> 619
<211> 30
<212> DNA
<213>Artificial sequence
<400> 619
AAAAGGCAGA GGAAGGGAGA GCTGGCTCTG 30
<201> 620
<211> 30
<212> DNA
<213>Artificial sequence
<400> 620
AAAAGGCAGA GGAAGGGAGA GCTGGCTCTC 30
<201> 621
<211> 30
<212> DNA
<213>Artificial sequence
<400> 621
CTCCAGGAAA GACAGAATGG TGCAGACTTG 30
<201> 622
<211> 30
<212> DNA
<213>Artificial sequence
<400> 622
CTCCAGGAAA GACAGAATGG TGCAGACTTC 30
<201> 623
<211> 30
<212> DNA
<213>Artificial sequence
<400> 623
AGTGAGTCCT CCCCACCGTT TAAAATGCAG 30
<201> 624
<211> 30
<212> DNA
<213>Artificial sequence
<400> 624
AGTGAGTCCT CCCCACCGTT TAAAATGCAC 30
<201> 625
<211> 30
<212> DNA
<213>Artificial sequence
<400> 625
ATATGCCCAT AAATAAATAC AATTTCTGAC 30
<201> 626
<211> 30
<212> DNA
<213>Artificial sequence
<400> 626
ATATGCCCAT AAATAAATAC AATTTCTGAG 30
<201> 627
<211> 30
<212> DNA
<213>Artificial sequence
<400> 627
GAAGCTGAGG GAAGAGGGCT GGAGAGGACA 30
<201> 628
<211> 30
<212> DNA
<213>Artificial sequence
<400> 628
GAAGCTGAGG GAAGAGGGCT GGAGAGGACT 30
<201> 629
<211> 30
<212> DNA
<213>Artificial sequence
<400> 629
GCAGCAAACC ACCATGGCAC ACATATACCT 30
<201> 630
<211> 30
<212> DNA
<213>Artificial sequence
<400> 630
GCAGCAAACC ACCATGGCAC ACATATACCA 30
<201> 631
<211> 30
<212> DNA
<213>Artificial sequence
<400> 631
TTTTCATGTT GTGACTTATA AACTCTACCT 30
<201> 632
<211> 30
<212> DNA
<213>Artificial sequence
<400> 632
TTTTCATGTT GTGACTTATA AACTCTACCA 30
<201> 633
<211> 30
<212> DNA
<213>Artificial sequence
<400> 633
CACAAACGTG TCTGTGTAAA ACTCTCCTTA 30
<201> 634
<211> 30
<212> DNA
<213>Artificial sequence
<400> 634
CACAAACGTG TCTGTGTAAA ACTCTCCTTT 30
<201> 635
<211> 30
<212> DNA
<213>Artificial sequence
<400> 635
TTTGCTGAGA ATGATGGTTG CCAGCTTCAT 30
<201> 636
<211> 30
<212> DNA
<213>Artificial sequence
<400> 636
TTTGCTGAGA ATGATGGTTG CCAGCTTCAA 30
<201> 637
<211> 30
<212> DNA
<213>Artificial sequence
<400> 637
AGATACAGTA GTATTAAGAT ATTTTGAAGT 30
<201> 638
<211> 30
<212> DNA
<213>Artificial sequence
<400> 638
AGATACAGTA GTATTAAGAT ATTTTGAAGA 30
<201> 639
<211> 30
<212> DNA
<213>Artificial sequence
<400> 639
GACATAAAAG ACAATGGAAA AGATCCTTTA 30
<201> 640
<211> 30
<212> DNA
<213>Artificial sequence
<400> 640
GACATAAAAG ACAATGGAAA AGATCCTTTT 30
<201> 641
<211> 30
<212> DNA
<213>Artificial sequence
<400> 641
CACACACACA CACACACACA CACACACTCT 30
<201> 642
<211> 30
<212> DNA
<213>Artificial sequence
<400> 642
CACACACACA CACACACACA CACACACTCA 30
<201> 643
<211> 30
<212> DNA
<213>Artificial sequence
<400> 643
ACACATCATA AAGTATTTTC AGAGATAACT 30
<201> 644
<211> 30
<212> DNA
<213>Artificial sequence
<400> 644
ACACATCATA AAGTATTTTC AGAGATAACA 30
<201> 645
<211> 30
<212> DNA
<213>Artificial sequence
<400> 645
AAAACATAAC TCTTAGTTTT CTTCTTGAAT 30
<201> 646
<211> 30
<212> DNA
<213>Artificial sequence
<400> 646
AAAACATAAC TCTTAGTTTT CTTCTTGAAA 30
<201> 647
<211> 30
<212> DNA
<213>Artificial sequence
<400> 647
GGAAAGAAGT AGTTTAAGGA AAGGTGTGAT 30
<201> 648
<211> 30
<212> DNA
<213>Artificial sequence
<400> 648
GGAAAGAAGT AGTTTAAGGA AAGGTGTGAA 30
<201> 649
<211> 30
<212> DNA
<213>Artificial sequence
<400> 649
GTTTGATAAA GCTTTCTATA TTTCTCTTTT 30
<201> 650
<211> 30
<212> DNA
<213>Artificial sequence
<400> 650
GTTTGATAAA GCTTTCTATA TTTCTCTTTA 30
<201> 651
<211> 30
<212> DNA
<213>Artificial sequence
<400> 651
CACACTGTGT TTTCAGTTCA GATTCTGTGA 30
<201> 652
<211> 30
<212> DNA
<213>Artificial sequence
<400> 652
CACACTGTGT TTTCAGTTCA GATTCTGTGT 30
<201> 653
<211> 30
<212> DNA
<213>Artificial sequence
<400> 653
CACTGTAAGT CAGAATGAAA GAAAAATAAT 30
<201> 654
<211> 30
<212> DNA
<213>Artificial sequence
<400> 654
CACTGTAAGT CAGAATGAAA GAAAAATAAA 30
<201> 655
<211> 30
<212> DNA
<213>Artificial sequence
<400> 655
CTTGATTTCC AGAATCCAAC TTTCAGGTGA 30
<201> 656
<211> 30
<212> DNA
<213>Artificial sequence
<400> 656
CTTGATTTCC AGAATCCAAC TTTCAGGTGT 30
<201> 657
<211> 30
<212> DNA
<213>Artificial sequence
<400> 657
TGATTGGTTT TTGTTCCTCC ACTCTTGCCT 30
<201> 658
<211> 30
<212> DNA
<213>Artificial sequence
<400> 658
TGATTGGTTT TTGTTCCTCC ACTCTTGCCA 30
<201> 659
<211> 30
<212> DNA
<213>Artificial sequence
<400> 659
ACTTAAATAT TGCAATTAAT TTTAGCATGA 30
<201> 660
<211> 30
<212> DNA
<213>Artificial sequence
<400> 660
ACTTAAATAT TGCAATTAAT TTTAGCATGT 30
<201> 661
<211> 30
<212> DNA
<213>Artificial sequence
<400> 661
AAAATGAGTC GTCTAGTATA ATACAAAATA 30
<201> 662
<211> 30
<212> DNA
<213>Artificial sequence
<400> 662
AAAATGAGTC GTCTAGTATA ATACAAAATT 30
Claims (2)
1. the DNA chip of the SNPs of noncoding region in the range of European crowd's full-length genome a kind of, is to be fixed with special spy
The DNA chip of pin；The specific probe is for detecting the probe of following 592 SNP：
2. DNA chip as described in claim 1, it is characterised in that：The specific probe is made of following 662 probes：Sequence
The single strand dna shown in single strand dna to the sequence 662 of sequence table shown in the sequence 1 of list.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810125333.5A CN108048562B (en) | 2018-02-07 | 2018-02-07 | A kind of DNA chip of the SNPs for the noncoding region within the scope of European crowd's full-length genome |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810125333.5A CN108048562B (en) | 2018-02-07 | 2018-02-07 | A kind of DNA chip of the SNPs for the noncoding region within the scope of European crowd's full-length genome |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108048562A true CN108048562A (en) | 2018-05-18 |
| CN108048562B CN108048562B (en) | 2019-02-05 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810125333.5A Active CN108048562B (en) | 2018-02-07 | 2018-02-07 | A kind of DNA chip of the SNPs for the noncoding region within the scope of European crowd's full-length genome |
Country Status (1)
| Country | Link |
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| CN (1) | CN108048562B (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102121046A (en) * | 2009-06-25 | 2011-07-13 | 中国科学院北京基因组研究所 | Chinese population linkage analysis single nucleotide polymorphism (SNP) marker sets and use method and application thereof |
| WO2011083312A1 (en) * | 2010-01-08 | 2011-07-14 | Oxford Gene Technology (Operations) Ltd | Combined cgh & allele-specific hybridisation method |
-
2018
- 2018-02-07 CN CN201810125333.5A patent/CN108048562B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102121046A (en) * | 2009-06-25 | 2011-07-13 | 中国科学院北京基因组研究所 | Chinese population linkage analysis single nucleotide polymorphism (SNP) marker sets and use method and application thereof |
| WO2011083312A1 (en) * | 2010-01-08 | 2011-07-14 | Oxford Gene Technology (Operations) Ltd | Combined cgh & allele-specific hybridisation method |
Non-Patent Citations (2)
| Title |
|---|
| BARBARA HRDLICKOVA等: "Genetic variation in the non-coding genome: Involvement of micro-RNAs and long non-coding RNAs in disease", 《BIOCHIMICA ET BIOPHYSICA ACTA》 * |
| NGOC-THUY HA, ET AL: "Coverage and efficiency in current SNP chips", 《EUROPEAN JOURNAL OF HUMAN GENETICS》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN108048562B (en) | 2019-02-05 |
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