CN108042135B

CN108042135B - Multifunctional load experiment movement device and system for magnetic resonance imaging and application thereof

Info

Publication number: CN108042135B
Application number: CN201810012520.2A
Authority: CN
Inventors: 郜发宝; 郑捷; 王磊; 陈榆舒
Original assignee: Individual
Current assignee: Individual
Priority date: 2018-01-05
Filing date: 2018-01-05
Publication date: 2023-09-01
Anticipated expiration: 2038-01-05
Also published as: CN108042135A

Abstract

The invention discloses a multifunctional load experiment motion device for magnetic resonance imaging, a magnetic resonance imaging load experiment system and application thereof. The multifunctional load experiment movement device for magnetic resonance imaging consists of a fixed plate, a foot placement and movement mechanism, a sliding guide rail assembly, a movement transmission assembly and an air pressure sensor. The magnetic resonance imaging load experiment system comprises magnetic resonance equipment, the multifunctional load experiment motion device for magnetic resonance imaging, a human body information detector, a gating unit, an analog-to-digital converter and a computer. The application of the magnetic resonance imaging load experiment system comprises the application of the system in calf load experiment exercise training, thigh load experiment exercise training, foot load experiment exercise training and heart load experiment exercise training and magnetic resonance scanning imaging.

Description

Multifunctional load experiment movement device and system for magnetic resonance imaging and application thereof

Technical Field

The invention belongs to the field of medical equipment, and relates to a multifunctional load experiment movement device for magnetic resonance imaging, a magnetic resonance imaging load experiment system and application thereof.

Background

The experimental exercise of load refers to the aerobic exercise process taking the isotonic contraction of muscle as energy consumption, and the exercise is accompanied with the decomposition of Adenosine Triphosphate (ATP) in human body, and the participation of contraction function realizes the obvious increase of red blood cells and blood flow of oxygen transported in skeletal muscle blood vessels. Vascular diseases such as atherosclerosis, diabetes, etc., are caused by the disruption of the peripheral blood circulation system, resulting in differences in metabolic levels of skeletal muscles such as blood perfusion and tissue blood oxygen, etc., from normal conditions. The skeletal muscle metabolism level can be estimated by utilizing the magnetic resonance imaging technology, and the skeletal muscle metabolism level in the calm state of the human body and the movement load state have larger difference, so that the difference can completely expose the metabolic profile which cannot be displayed by the human body under the static state.

In order to evaluate skeletal muscle metabolism level under the motion load state of human body by using the magnetic resonance imaging technology, the presently disclosed lower limb load motion experiment and the used device have the following technical schemes: a Skinner-Gardner plate test (Gardner AW, skinner JS, et al progressive vs. single-stage treadmill tests for evaluation of claudication. Med Sci Sports Exerc) for exercise training of lower limb loads of a human body, the test being a way of a person walking on a treadmill for a certain period of time as a means of applying leg loads; the dorsiflexion movement of the front end of the human foot in the magnet, the load movement pattern of the weight (5.58 kg) is pulled up by nylon ropes and pulleys (functional MRI study of skeletal muscle movement and blood perfusion and water molecule diffusion after ice compress, li Feng, doctor's paper); the Toe-flex experiment (Jie Zheng, mary K. Hastings, david Muccirross, et al, non-contrast MRI perfusion angiosome in diabetic feet. Eur radio) for foot load exercise training, which is to perform load exercise of skeletal muscles of the foot in a Toe-bending manner; legs were trained with feet by a plant-flex gauge and were magnetic resonance compatible (David c.isbell, frederick h.epstein, et al calf Muscle Perfusion at Peak Exercise in Peripheral Arterial Disease: measurement by First-Pass Contrast-Enhanced Magnetic Resonance imaging j Magn Reson Imaging). However, in the above scheme, the Skinner-Gardner plate experiment is that the human body completes the load movement outside the magnetic resonance, and then enters the magnet to perform the magnetic resonance scanning, so that the level of skeletal muscle metabolism in the movement training process cannot be reflected in real time; the load movement of lifting the weight through the nylon rope and the pulley can not quantify the movement strength, and the movement fatigue of a human body is easily caused; the Toe-flex experiment is also unable to quantify the intensity of motion of the foot; the plant-flex meter is a device similar to two bicycle pedals, a subject moves at a set speed (10-12 circles in one minute) until the subject can not step forcefully to stop exercise training, and as the subject uses the foot, the leg and the thigh muscles to move simultaneously, the movement tolerance of which part of the muscles reaches the highest value cannot be determined, the accurate positioning of target skeletal muscles is lacking, and the movement tolerance level of the muscles at each part is difficult to evaluate.

In the field of magnetic resonance imaging, there are also methods for cardiac load magnetic resonance imaging by drug injection in which K Mc Entee et al achieve cardiac load by injection of dobutamine (K Mc Entee, H Amory, et al cardiac stress testing in conscious healthy dogs.Esvim Meing, 1996) into dogs, and later KK Balan, T Leitha et al do cardiac load imaging by injection of adenosine and dipyridamole respectively into patients (KK Balan, M Crithley. Is the dyspnea during adenosine cardiac stress test caused by bronchospasm. American Heart Journal,2001,142 (1): 142.T Leitha,M Gwechenberger,S Falger-Banyai. Act effects on pulmonary airflow of intravenous dipyridamole cardiac stress test. European Journal of Nuclear Medicine & Molecular Imaging,1995 (22): 1408-1410). The principle of the method for injecting the medicine is to promote the electrocardio and the cardiac output of the organism to be passively increased, so as to simulate the condition that the representative heart is in a loading state. However, this method has the following problems with respect to the exercise load: firstly, the medicine can increase the electrocardio and cardiac output of the organism passively, does not accord with the condition of actual heart load, and does not simulate the actual load state in terms of heart load imaging; secondly, the injection of the medicine is an invasive method, and the medicine is injected into the blood circulation system through a vascular channel of the body and flows through the whole body everywhere through the heart; third, safety concerns are associated with the risk of patients suffering from heart disease from rapid changes in their cardiac electrical and cardiac output due to individual differences, especially in the presence of drugs.

Disclosure of Invention

Aiming at the defects and problems in the prior art, the invention provides a multifunctional load experiment movement device for magnetic resonance imaging, a magnetic resonance imaging load experiment system and application thereof, so as to realize load experiment movement training on thigh, calf and foot skeletal muscles of a subject respectively, obtain real-time movement intensity data of each part of lower limbs of the subject, be compatible with magnetic resonance magnetic fields and provide basis for evaluating skeletal muscle metabolism level under a human movement load state.

The invention relates to a multifunctional load experiment movement device for magnetic resonance imaging, which consists of a fixed plate, a foot placement and movement mechanism, a sliding guide rail assembly, a movement transmission assembly and an air pressure sensor; the foot placement and movement mechanism comprises an ankle placement piece, a foot surface pedal, a limiting plate, a limiting bolt and a sliding base; the ankle placing piece mainly comprises a supporting table and an ankle placing groove positioned on the supporting table, and the bottom surface of the supporting table is fixedly connected with the sliding base; the lower sections of the two side surfaces of the pedal are respectively provided with a first limit hole matched with the limit bolt in size, the pedal is positioned at one end of the ankle placing groove, and the lower end of the pedal is hinged with the supporting table; the two limiting plates are respectively provided with a plurality of second limiting holes, each second limiting hole Kong Xiangge is distributed in an arc shape at a certain interval, corresponds to the height position of the first limiting hole and is matched with the size of the limiting bolt, and the two limiting plates are respectively positioned on two sides of the foot pedal and fixedly connected with the supporting table; the sliding guide rail assembly consists of two sliding guide rails and at least two sliding limiting pieces; the motion transmission component is an air bag and piston cylinder combination; the combination of the above components or members: the two sliding guide rails are arranged on the fixed plate in parallel, and the interval between the two sliding guide rails is matched with the width of the sliding base; the foot placement and movement mechanism is placed on the fixed plate and is positioned between the two sliding guide rails, and a sliding base in the foot placement and movement mechanism is combined with the two sliding guide rails to form a sliding pair; the sliding limiting piece is combined with third limiting holes arranged on the two sliding guide rails to fix the foot placement and movement mechanism at a required position or limit the foot placement and movement mechanism in a required sliding range; the air bag is arranged at the upper part of the surface of the pedal facing the ankle placing groove, a piston rod in the piston cylinder assembly is hinged with the surface of the pedal facing away from the ankle placing groove, and the bottom end of the cylinder is hinged with the fixed plate; the signal receiving end of the air pressure sensor is respectively combined with air inlets arranged on the air bag wall and the air cylinder wall.

In the multifunctional load experiment movement device for magnetic resonance imaging, the ankle placing groove is detachably connected with the supporting table through a screw; or two supporting plates are arranged and are respectively positioned at two sides of the ankle placing groove and are arranged on the sliding base, and two side surfaces of the ankle placing groove are respectively detachably connected with the two supporting plates through screws. Such a structure facilitates replacement of the ankle placement slot to accommodate different subjects.

In the multifunctional load experiment motion device for magnetic resonance imaging, the fixing plate, the foot placement and motion mechanism, the sliding guide rail assembly and the motion transmission assembly are made of acetal resin (POM), polytetrafluoroethylene or rubber so as to be compatible with a magnetic resonance magnetic field and ensure the magnetic resonance imaging quality.

In the multifunctional load experiment movement device for magnetic resonance imaging, the sliding rail limiting part can be a bolt and buckle assembly or a bolt and nut assembly.

The multifunctional load experiment movement device for magnetic resonance imaging can be combined into a set of load experiment movement system by two parallel parts, so that the device can be used for simultaneously performing movement load training on two legs of a human body, and can also be used singly for performing load movement training on one leg of the human body.

The invention relates to a magnetic resonance imaging load experiment system, which comprises magnetic resonance equipment, the multifunctional load experiment motion device for magnetic resonance imaging, a human body information detector, a gate control unit, an analog/digital converter and a computer, wherein the magnetic resonance equipment comprises a magnetic resonance scanning bed; the ankle placement piece in the multifunctional load experiment movement device for magnetic resonance imaging is combined with the magnetic resonance scanning bed, and the air pressure sensor in the multifunctional load experiment movement device for magnetic resonance imaging is electrically connected with the analog-to-digital converter, so that the acquired air pressure signal representing the load experiment movement intensity of the subject is converted into an analog signal and is transmitted to the analog-to-digital converter; the human body information detector is electrically connected with the analog-to-digital converter and transmits the detected analog signals reflecting the physiological conditions of the subjects to the analog-to-digital converter; the computer is electrically connected with the analog-to-digital converter, the magnetic resonance equipment and the gating unit respectively; the analog/digital converter converts the analog signals from the air pressure sensor and the human body information detector into digital signals respectively and transmits the digital signals to the computer; the computer calculates and processes the received digital signals representing the exercise intensity of the load experiment of the subject to form real-time exercise intensity data of the subject, stores and displays the real-time exercise intensity data and sends the data to the gating unit, calculates and processes the received digital signals reflecting the physiological condition of the subject to form physiological condition data of the subject, stores and displays the physiological condition data and sends the physiological condition data to the gating unit; the computer is also used for controlling the magnetic resonance equipment to perform magnetic resonance scanning, receiving a scanning result digital signal input by the magnetic resonance equipment, and processing the received scanning result digital signal to form a magnetic resonance image for storage and display;

The gating unit is electrically connected with the magnetic resonance equipment, the gating unit is provided with a physiological condition data threshold value and a motion intensity data threshold value of the subject, and when the physiological condition and the motion intensity data of the subject input by the computer reach the threshold value, the gating unit generates a gating signal and outputs the gating signal to the magnetic resonance equipment to control the magnetic resonance equipment to perform magnetic resonance scanning.

In the magnetic resonance imaging load experiment system, the human body information detector is at least one of an electrocardiograph detector, a blood pressure detector and a respiratory detector.

The application of the magnetic resonance imaging load experiment system comprises the steps of applying the system to calf load experiment exercise training, thigh load experiment exercise training, foot load experiment exercise training and heart load experiment exercise training and magnetic resonance scanning imaging.

1. The shank load experiment exercise training and the magnetic resonance scanning imaging are operated as follows:

(1) allowing a subject to lie on the back on the magnetic resonance scanning bed, placing the tested legs of the subject in leg supporting grooves of the magnetic resonance scanning bed, winding a flexible magnetic resonance coil, and entering a magnet in a leg advanced mode;

(2) taking down an air bag in a multifunctional load experiment movement device for magnetic resonance imaging, filling compressed air into a cylinder of a piston cylinder assembly to stop the air filling after the piston is positioned at the top end of the cylinder, and combining a signal receiving end of an air pressure sensor with an air inlet hole arranged on the cylinder wall;

(3) The method comprises the steps that a foot of a tested leg is placed on an ankle placing groove of a multifunctional load experiment movement device for magnetic resonance imaging by a subject, the rotation range of a pedal on the foot surface of the subject is adjusted, the rotation range is controlled to be within the range that the pedal on the foot surface of the subject can be stepped on, then two limiting bolts are respectively combined with a corresponding group of second limiting holes on two limiting plates, and then the two limiting bolts are respectively combined with the corresponding other group of second limiting holes on the two limiting plates, so that the pedal on the foot surface is limited in the determined rotation range; then the foot placement and movement mechanism is fixed at the position through the combination of the sliding limiting piece and a third limiting hole arranged on the sliding guide rail;

(4) informing a subject of the required exercise intensity, then enabling the subject to pedal the foot pedal, enabling the foot pedal to rotate back and forth around the hinge shaft of the foot pedal between the two groups of second limiting holes, and accordingly enabling the air pressure in the air cylinder to change, enabling the air pressure sensor to convert the acquired air pressure signal representing the experimental exercise intensity of the calf load of the subject into an analog signal and transmitting the analog signal to the analog-to-digital converter, and enabling the analog-to-digital converter to convert the analog signal from the air pressure sensor into a digital signal and transmitting the digital signal to the computer; the computer calculates and processes the received digital signals representing the experimental exercise intensity of the calf load of the subject to form real-time exercise intensity data of the calf of the subject to be stored and displayed, the subject observes the exercise intensity displayed by the computer in real time, and adjusts the pedaling exercise intensity according to the exercise intensity displayed by the computer until the required exercise intensity is reached;

During the calf load experiment exercise training, the computer is used for controlling the magnetic resonance equipment to perform resting state or/and equidistant state magnetic resonance scanning imaging according to the requirement;

when dynamic scanning imaging is needed, the subject lead human body information detector is controlled by the gating unit to perform dynamic scanning imaging;

the magnetic resonance apparatus transmits the digital signals of the scan results to a computer, which processes the received digital signals of the scan results to form a magnetic resonance image for storage and display.

2. Thigh load experiment exercise training and magnetic resonance scanning imaging are performed as follows:

(3) the method comprises the steps that a foot of a tested leg is placed on an ankle placing groove of a multifunctional load experiment movement device for magnetic resonance imaging by a subject, a foot pedal is rotated, a limiting bolt is inserted into a second limiting hole formed in a limiting plate and a first limiting hole formed in the side face of the foot pedal, the foot pedal is fixed, then the sliding range of the foot placing and movement mechanism along a sliding guide rail is adjusted, the sliding range is controlled in a range that the foot surface of the subject can vertically apply force to the foot pedal, and then the foot placing and movement mechanism is limited in the determined sliding range through the combination of two or two groups of sliding limiting pieces and a third limiting hole formed in the sliding guide rail;

(4) Informing a subject of the required movement intensity, then enabling the subject to apply force to the foot pedal, enabling the foot placement and movement mechanism to slide in a reciprocating translation manner along the sliding guide rail within a determined range, so that the gas pressure in the cylinder is changed, converting the acquired gas pressure signal representing the thigh load experimental movement intensity of the subject into an analog signal by the gas pressure sensor, and transmitting the analog signal to the analog-to-digital converter, and converting the analog signal from the gas pressure sensor into a digital signal and transmitting the digital signal to the computer by the analog-to-digital converter; the computer calculates and processes the received digital signals representing the thigh load experiment exercise intensity of the subject to form thigh real-time exercise intensity data of the subject to be stored and displayed, the subject observes the exercise intensity displayed by the computer in real time, and adjusts the force application intensity of the pedal on the foot surface according to the exercise intensity displayed by the computer until the force application intensity reaches the required exercise intensity;

during thigh load experiment exercise training, the computer controls the magnetic resonance equipment to perform resting state or/and equidistant state magnetic resonance scanning imaging according to the requirement;

3. Foot load experiment exercise training and magnetic resonance scanning imaging are carried out, and the operation is as follows:

(1) allowing a subject to lie on the back on the magnetic resonance scanning bed, placing the tested legs of the subject in leg supporting grooves of the magnetic resonance scanning bed, entering a magnet in a leg advanced mode, and winding a flexible magnetic resonance coil on the foot;

(2) filling compressed air into an air bag in the multifunctional load experiment movement device for magnetic resonance imaging, stopping filling when the air bag is in a filling state, and combining a signal receiving end of the air pressure sensor with an air inlet hole arranged on the air bag wall;

(3) placing the foot of a tested leg on an ankle placing groove of a multifunctional load experiment movement device for magnetic resonance imaging by a subject, rotating a foot pedal to enable the foot pedal to be in contact with the foot surface of the subject, inserting a limiting bolt into a second limiting hole formed in the limiting plate and a first limiting hole formed in the side surface of the foot pedal, fixing the foot pedal at the position, and fixing the foot placing and movement mechanism through the combination of two or two groups of sliding limiting pieces and a third limiting hole formed in a sliding guide rail;

(4) Informing a subject of the required exercise intensity, bending and squeezing the toes of the subject to squeeze the air bag, so that the air pressure in the air bag is changed, and converting the acquired air pressure signal representing the experimental exercise intensity of the foot load of the subject into an analog signal by the air pressure sensor and transmitting the analog signal to the analog/digital converter, wherein the analog/digital converter converts the analog signal from the air pressure sensor into a digital signal and transmits the digital signal to the computer; the computer calculates and processes the received digital signals representing the motion intensity of the foot load experiment of the subject to form the real-time motion intensity data of the foot of the subject to be stored and displayed, the subject observes the motion intensity displayed by the computer in real time, and adjusts the extrusion force intensity of the air bag to reach the required motion intensity according to the motion intensity displayed by the computer;

during the foot load experiment exercise training, the computer controls the magnetic resonance equipment to perform resting state or/and equidistant state magnetic resonance scanning imaging according to the requirement;

4. The heart load experiment exercise training and the magnetic resonance scanning imaging are operated as follows:

(1) installing a human body information detector on a subject, allowing the subject to lie on the back on a magnetic resonance scanning bed, placing a magnetic resonance special coil on the chest part of the subject, and entering a magnet in a head advanced mode;

(2) selecting and referring to the above-mentioned shank load experiment movement or thigh load experiment movement to train, and informing the subject of the required movement strength, and respectively converting the analog signal from the air pressure sensor and the analog signal from the human body information detector into digital signals by using analog-to-digital converter, and transferring them to computer; the computer calculates and processes the received digital signals representing the exercise intensity of the load experiment of the subject to form real-time exercise intensity data of the subject, stores and displays the real-time exercise intensity data and sends the data to the gating unit, calculates and processes the received digital signals reflecting the physiological condition of the subject to form physiological condition data of the subject, stores and displays the physiological condition data and sends the physiological condition data to the gating unit; the subject observes the movement intensity displayed by the computer in real time, and adjusts the force application intensity according to the movement intensity displayed by the computer until the required movement intensity is reached; when the physiological condition data and the movement intensity data of the subject received by the gating unit reach a set threshold value, the gating unit controls the magnetic resonance equipment to perform dynamic scanning imaging; the magnetic resonance apparatus transmits the digital signals of the scan results to a computer, which processes the received digital signals of the scan results to form a magnetic resonance image for storage and display.

The resting state magnetic resonance scanning imaging refers to that after a specific training task is completed and a set motion strength is reached, a subject stops moving and keeps the muscle group of a tested part in a relaxed state all the time, and magnetic resonance scanning imaging is carried out.

The equidistant (isometric exercise) magnetic resonance scanning imaging refers to magnetic resonance scanning performed by setting a motion intensity to enable the muscle group of the tested part to be kept in a tension state and the length of the muscle to be kept unchanged all the time, namely the motion posture of the tested part is kept unchanged when the tested part performs a training task.

The dynamic (dynamic exercise) scanning imaging refers to that when the physiological condition data and the motion intensity data of the subject received by the gating unit reach a set threshold value during the exercise training of the load experiment, the gating unit controls the magnetic resonance device to perform dynamic scanning imaging, namely, the dynamic scanning imaging is the scanning imaging performed in the continuous change of the motion gesture of the subject.

The invention has the following beneficial effects:

1. the multifunctional load experiment exercise device for magnetic resonance imaging can realize load experiment exercise training on thigh, shank and foot skeletal muscles of a subject, so that the device can perform various exercises, thereby saving the cost of purchasing similar devices and saving the placement space.

2. The multifunctional load experiment movement device for magnetic resonance imaging accords with the human engineering principle, and the foot placement and movement mechanism can be adjusted according to different subjects before movement training so as to set maximum and minimum movement amplitude, facilitate quantification and control of movement intensity, increase the comfort of load movement training of people and reduce uncomfortable feeling caused by long-time use of the device.

3. The multifunctional load experiment movement device for magnetic resonance imaging has a simple structure, and can realize the switching of the load experiment movement training of different parts of the lower limb through the different combinations of the limiting plug pin, the first limiting hole, the second limiting hole and the combination of the sliding limiting piece and the third limiting hole on the sliding guide rail, so that the device is easy to grasp and use, and is convenient to popularize and use.

4. The multifunctional load experiment movement device for magnetic resonance imaging is compatible with a magnetic resonance magnetic field, and a magnetic resonance imaging load experiment system formed by the device, magnetic resonance equipment, a computer and the like can enable a subject to complete load experiment movement training of different parts of the lower limb in the magnetic field, and can carry out resting state, equidistant state and dynamic magnetic resonance scanning imaging on the different parts of the lower limb of the subject, so that powerful technical support is provided for evaluating skeletal muscle metabolism level under the movement load state of a human body by applying a magnetic resonance imaging technology.

5. The components of the magnetic resonance imaging load experiment system are coordinated and matched, and information collected by the real-time feedback sensor and the human body information detector is displayed, so that a subject can know the motion condition and physiological state of the subject in real time, the motion intensity can be conveniently adjusted, and especially, the motion and dynamic imaging tend to be consistent by carrying out dynamic magnetic resonance scanning imaging under the motion state of the subject, and motion imaging artifacts are reduced.

6. The magnetic resonance imaging load experiment system can immediately perform magnetic resonance scanning imaging after the subject reaches the training target strength, so that the preparation time from the completion of exercise training to the imaging of the traditional exercise training experiment is saved, and the level of skeletal muscle metabolism can be accurately reflected in real time.

7. The application of the magnetic resonance imaging load experiment system also provides a heart load experiment exercise training method, avoids negative effects caused by the traditional medicine injection method, is safer and more effective, and reduces the risk of a subject.

Drawings

Fig. 1 is a schematic structural diagram of a multifunctional load experiment motion device for magnetic resonance imaging.

Fig. 2 is a top view of fig. 1.

Fig. 3 is a schematic structural diagram of a foot placement and movement mechanism in the multifunctional load experiment movement device for magnetic resonance imaging.

Fig. 4 is an exploded view of fig. 3.

Fig. 5 is a schematic diagram of the position of the pedal in the multifunctional loading experiment exercise apparatus for magnetic resonance imaging according to the present invention when the calf loading experiment exercise is performed.

Fig. 6 is a schematic diagram of the position of the foot placement and movement mechanism in the multifunctional loading experiment movement device for magnetic resonance imaging according to the invention when thigh loading experiment movement is performed.

Fig. 7 is a schematic diagram of an air bag in an uncompressed state in the multifunctional load experiment exercise apparatus for magnetic resonance imaging according to the present invention when performing a foot load experiment exercise.

Fig. 8 is a schematic diagram of an air bag in a pressed state in the multifunctional load experiment exercise apparatus for magnetic resonance imaging according to the present invention when a foot load experiment exercise is performed.

Fig. 9 is a block diagram of a magnetic resonance imaging load experiment system according to the present invention.

In the figure, a fixing plate 1, a foot placement and movement mechanism 2, a foot ankle placement piece 3-1, a foot ankle placement groove 3-2, a supporting platform 3-2, a foot pedal 4, a first limiting hole 4-1, a hinged connecting piece 4-2, a limiting plate 5, a second limiting hole 5-1, a limiting bolt 6, an air bag 7, a sliding base 8, a sliding guide rail 9, a third limiting hole 9-1, a sliding limiting piece 10, a piston rod 11, a cylinder 12, a supporting plate 13, a pneumatic sensor 14, a multifunctional load experiment movement device 15 for magnetic resonance imaging, a magnetic resonance device 16, a magnetic resonance scanning bed 16-1, a human body information detector 17, a gating unit 18, an analog/digital converter 19 and a computer 20.

Detailed Description

The multifunctional load experiment motion device for magnetic resonance imaging, the magnetic resonance imaging load experiment system and the application thereof are further described below through embodiments and with reference to the accompanying drawings. It should be noted that the examples given should not be construed as limiting the scope of the present invention, and that some insubstantial modifications and adjustments of the present invention could still be made by those skilled in the art in light of the present disclosure.

Example 1

The embodiment is a multifunctional load experiment movement device for magnetic resonance imaging, and the structure of the device is shown in fig. 1-4, and the device consists of a fixed plate 1, a foot placement and movement mechanism 2, a sliding guide rail assembly, a movement transmission assembly and an air pressure sensor 14.

The foot placement and movement mechanism 2 comprises an ankle placement piece 3, a foot pedal 4, a limiting plate 5, a limiting bolt 6 and a sliding base 8; the ankle placing piece 3 consists of a supporting table 3-2, an ankle placing groove 3-1 positioned on the supporting table and two supporting plates 13, wherein the bottom surface of the supporting table is fixedly connected with the sliding base 8, the two supporting plates are respectively positioned at two sides of the ankle placing groove 3-1 and are arranged on the sliding base 8, and two side surfaces of the ankle placing groove 3-1 are respectively detachably connected with the two supporting plates through screws; the lower sections of the two side surfaces of the foot pedal 4 are respectively provided with a first limit hole 4-1 which is matched with the limit bolt 6 in size, the foot pedal is positioned at one end of the ankle placing groove 3-1, and the lower end of the foot pedal is hinged with the supporting table 3-2; the limiting plates 5 are two sector plates, a plurality of second limiting holes 5-1 are formed in the two limiting plates, each second limiting hole Kong Xiangge is distributed in a circular arc shape at an interval, the second limiting holes correspond to the height positions of the first limiting holes 4-1 and are matched with the size of the limiting bolts 6, and the two limiting plates are respectively located on two sides of the foot pedal 4 and fixedly connected with the supporting table.

The sliding guide rail assembly consists of two sliding guide rails 9 and sliding limiting parts 10, wherein strip-shaped third limiting holes 9-1 are formed in the side surfaces of the two sliding guide rails 9, and the sliding limiting parts 10 comprise four bolts and four nuts; the motion transmission assembly is an air bag 7 and a piston cylinder assembly, an air inlet is arranged on the wall of the air bag 7, the piston cylinder assembly mainly comprises an air cylinder 12, a piston and a piston rod 11, and the air inlet is arranged on the wall of the air cylinder 12.

The combination mode of the components and the members is as follows: two sliding guide rails 9 are arranged on the fixed plate 1 in parallel with each other, and the interval between the two sliding guide rails is matched with the width of the sliding base 8; the foot placement and movement mechanism 2 is placed on the fixed plate 1 and is positioned between the two sliding guide rails 9, and a sliding base 8 in the foot placement and movement mechanism is combined with the two sliding guide rails 9 to form a sliding pair; the sliding limiting piece 10 is combined with the strip-shaped third limiting holes 9-1 arranged on the two sliding guide rails to fix the foot placement and movement mechanism at a required position or limit the foot placement and movement mechanism within a required sliding range; the air bag 7 is arranged at the upper part of the surface of the foot pedal 4 facing the ankle placing groove 3-1, a piston rod 11 in the piston cylinder assembly is hinged with the surface of the foot pedal 4 facing away from the ankle placing groove 3-1 through a hinged connecting piece 4-2, and the bottom end of a cylinder 12 is hinged with the fixed plate 1; the signal receiving end of the air pressure sensor 14 is respectively combined with air inlets arranged on the wall of the air bag 7 and the wall of the air cylinder 12.

In this embodiment, the air pressure sensor 14 is a Model 31 air pressure sensor (West Coast Research Corporation, U.S.); the fixing plate 1, the foot placement and movement mechanism, the sliding guide rail assembly and the piston cylinder assembly are made of polytetrafluoroethylene, and the air bag 7 is made of rubber.

Example 2

The structure of the magnetic resonance imaging load experiment system is shown in fig. 9, and the system comprises a magnetic resonance device 16 including a magnetic resonance scanning bed 16-1, a multifunctional load experiment motion device 15 for magnetic resonance imaging, a human body information detector 17, a gate control unit 18, an analog/digital converter 19 and a computer 20. The magnetic resonance device 16 is a Magnetom skyra 3.0T MR (siemens company), the human body information detector 17 is an electrocardiograph detector, a respiratory detector and a blood pressure detector, the gating unit 18 is a SAII 1030 monitoring gating system (SA Instruments company in usa), the analog/digital converter 19 is a USB-6009 processing hardware system (National Instruments company in usa), and the computer 20 is provided with a magnetic resonance ParaVision version6.0 operating platform software (Bruker, germany).

The ankle placement part 3 in the multifunctional load experiment moving device 15 for magnetic resonance imaging is combined with the magnetic resonance scanning bed 16-1, and the air pressure sensor 14 in the multifunctional load experiment moving device 15 for magnetic resonance imaging is electrically connected with the analog-to-digital converter 19, so that the collected air pressure signal representing the load experiment moving intensity of the subject is converted into an analog signal and then transmitted to the analog-to-digital converter 19.

The human body information detector 17 is electrically connected to the analog/digital converter 19, and transmits the detected analog signal reflecting the physiological condition of the subject to the analog/digital converter 19.

The computer 20 is electrically connected with the analog/digital converter 19, the magnetic resonance device 16 and the gate control unit 18 respectively; the analog/digital converter 19 converts the analog signal from the air pressure sensor 14 and the analog signal from the human body information detector 17 into digital signals, respectively, and transmits the digital signals to the computer 20; the computer 20 calculates and processes the received digital signals representing the exercise intensity of the load experiment of the subject to form real-time exercise intensity data of the subject, stores and displays the real-time exercise intensity data and transmits the data to the gating unit 18, calculates and processes the received digital signals reflecting the physiological condition of the subject to form physiological condition data of the subject, stores and displays the physiological condition data and transmits the physiological condition data to the gating unit 18; the computer 20 is also used to control the magnetic resonance apparatus 16 for magnetic resonance scanning and to receive the scan result digital signals input by the magnetic resonance apparatus, and to process the received scan result digital signals to form magnetic resonance images for storage and display.

The gating unit 18 is electrically connected to the magnetic resonance device 16, and is provided with a physiological condition data threshold and a motion intensity data threshold of the subject, and when the physiological condition and the motion intensity data of the subject input by the computer 20 reach the threshold, the gating unit generates a gating signal and outputs the gating signal to the magnetic resonance device 16 to control the magnetic resonance device 16 to perform magnetic resonance scanning.

Example 3

This example is a first application of the magnetic resonance imaging loadometer system of example 2, using the system of example 2 for the loadometer exercise training and magnetic resonance scanning imaging, and operates as follows:

(1) allowing the subject to lie on his back on the magnetic resonance scanning bed 16-1, placing his test leg in the leg support groove of the magnetic resonance scanning bed, winding a flexible magnetic resonance coil, and entering the magnet in a leg advanced manner;

(2) taking down an air bag 7 in the multifunctional load experiment movement device for magnetic resonance imaging, filling compressed air into a cylinder 12 of a piston cylinder assembly to stop the air filling after the piston is positioned at the top end of the cylinder, and combining a signal receiving end of an air pressure sensor 14 with an air inlet hole arranged on the wall of the cylinder 12;

(3) placing the feet of the tested legs on an ankle placing groove 3-1 of a multifunctional load experiment movement device for magnetic resonance imaging, adjusting the rotation range of the foot pedal 4, controlling the rotation range to be within the range that the foot surface of the tested can pedal the foot pedal 4, combining two limiting bolts 6 with a corresponding group of second limiting holes 5-1 on two limiting plates 5 respectively, combining two limiting bolts 6 with another corresponding group of second limiting holes 5-1 on two limiting plates 5 respectively, and limiting the foot pedal 4 within the determined rotation range; then the foot placement and movement mechanism is fixed at the position through the combination of the sliding limiting piece 10 and the third limiting hole 9-1 arranged on the sliding guide rail 9;

(4) Informing the subject of the required exercise intensity, then allowing the subject to step on the foot pedal 4, so that the foot pedal can reciprocally rotate around the hinge shaft of the foot pedal between the two groups of second limiting holes, and the air pressure in the air cylinder 12 is changed, the air pressure sensor 14 converts the acquired air pressure signal into an analog signal and transmits the analog signal to the analog-to-digital converter 19, and the analog-to-digital converter 19 converts the analog signal from the air pressure sensor 14 into a digital signal and transmits the digital signal to the computer 20; the computer 20 calculates and processes the received digital signals representing the experimental exercise intensity of the load of the lower leg of the subject to form real-time exercise intensity data of the lower leg of the subject to be stored and displayed, the subject observes the exercise intensity displayed by the computer in real time, and adjusts the pedaling exercise intensity according to the exercise intensity displayed by the computer until the required exercise intensity is reached;

during the calf load experiment exercise training, the computer 20 controls the magnetic resonance equipment 16 to carry out resting state magnetic resonance scanning imaging, the magnetic resonance equipment 16 transmits digital signals of scanning results to the computer 20, and the computer 20 processes the received digital signals of the scanning results to form magnetic resonance images for storage and display.

Example 4

This example is a second application of the magnetic resonance imaging loadometer system of example 2, using the system of example 2 for thigh loadometer exercise training and magnetic resonance scanning imaging, and operating as follows:

(3) placing the foot of a tested leg on an ankle placing groove 3-1 of a multifunctional load experiment movement device for magnetic resonance imaging by a subject, rotating a foot pedal 4, inserting a limiting bolt 6 into a second limiting hole 5-1 arranged on a limiting plate and a first limiting hole 4-1 arranged on the side surface of the foot pedal, fixing the foot pedal, adjusting the sliding range of a foot placing and movement mechanism along a sliding guide rail 9, controlling the sliding range to be in a range in which the foot surface of the subject can vertically apply force to the foot pedal 4, and limiting the foot placing and movement mechanism in the determined sliding range by combining two or two groups of sliding limiting pieces 10 with a third limiting hole 9-1 arranged on the sliding guide rail 9;

(4) Informing the subject of the required movement intensity, then applying force to the foot pedal 4 by the subject, and enabling the foot placement and movement mechanism to slide in a reciprocating translation way along the sliding guide rail 9 within a determined range, so that the gas pressure in the gas cylinder 12 is changed, the gas pressure sensor 14 converts the acquired gas pressure signal into an analog signal and transmits the analog signal to the analog-to-digital converter 19, and the analog-to-digital converter 19 converts the analog signal from the gas pressure sensor 14 into a digital signal and transmits the digital signal to the computer 20; the computer 20 calculates and processes the received digital signals representing the thigh load experiment exercise intensity of the subject, forms thigh real-time exercise intensity data of the subject to be stored and displayed, and the subject observes the exercise intensity displayed by the computer in real time and adjusts the force application intensity of the foot pedal 4 according to the exercise intensity displayed by the computer until the required exercise intensity is reached;

during foot load experimental exercise training, the computer 20 controls the magnetic resonance device 16 to perform equidistant magnetic resonance scanning imaging; the magnetic resonance apparatus 16 transmits the digital signals of the scan results to the computer 20, and the computer 20 processes the received digital signals of the scan results to form magnetic resonance images for storage and display.

Example 5

This example is a third application of the magnetic resonance imaging loadometer system of example 2, using the system of example 2 for foot loadometer exercise training and magnetic resonance scanning imaging, and operating as follows:

(1) allowing the subject to lie on his back on the magnetic resonance scanning bed 16-1, placing his test leg in the leg support groove of the magnetic resonance scanning bed, entering the magnet in a leg advanced manner, and winding a flexible magnetic resonance coil on the foot;

(2) filling compressed air into an air bag 7 in the multifunctional load experiment movement device for magnetic resonance imaging, stopping filling when the air bag is in a filling state, and combining a signal receiving end of an air pressure sensor 14 with an air inlet hole arranged on the wall of the air bag 7;

(3) placing the foot of a tested leg on an ankle placing groove 3-1 of a multifunctional load experiment movement device for magnetic resonance imaging by a subject, rotating a foot pedal 4 to enable the foot pedal to be in contact with the foot surface of the subject, inserting a limiting bolt 6 into a second limiting hole 5-1 arranged on a limiting plate and a first limiting hole 4-1 arranged on the side surface of the foot pedal, fixing the foot pedal at the position, and fixing the foot with a movement mechanism through the combination of two or two groups of sliding limiting pieces 10 and a third limiting hole 9-1 arranged on a sliding guide rail 9;

(4) Informing the subject of the required exercise intensity, and then bending and squeezing the air bag 7 by the toe of the subject, so that the air pressure in the air bag 7 is changed, the air pressure sensor 14 converts the acquired air pressure signal into an analog signal and transmits the analog signal to the analog/digital converter 19, and the analog/digital converter 19 converts the analog signal from the air pressure sensor 14 into a digital signal and transmits the digital signal to the computer 20; the computer 20 calculates and processes the received digital signals representing the experimental exercise intensity of the foot load of the subject, forms the real-time exercise intensity data of the foot of the subject to be stored and displayed, and the subject observes the exercise intensity displayed by the computer in real time and adjusts the extrusion force intensity of the air bag 7 according to the exercise intensity displayed by the computer until the required exercise intensity is achieved;

during foot load experimental exercise training, the computer 20 controls the magnetic resonance device 16 to perform resting magnetic resonance scanning imaging; the magnetic resonance apparatus 16 transmits the digital signals of the scan results to the computer 20, and the computer 20 processes the received digital signals of the scan results to form magnetic resonance images for storage and display.

Example 6

This example is a fourth application of the magnetic resonance imaging loadometer system of example 2, wherein the system of example 2 is used for cardiac loadometer exercise training and magnetic resonance scanning imaging, and operates as follows:

(1) Leading an electrocardiograph detector, a blood pressure detector and a respiratory detector on a subject, allowing the subject to lie on the back of a magnetic resonance scanning bed, placing a magnetic resonance special coil on the chest part of the subject, and entering a magnet in a head advanced mode;

(2) the thigh load experiment exercise described in example 4 was selected and referred to for training, and the subject was informed of the required exercise intensity, and the analog-to-digital converter 18 converts the analog signals from the air pressure sensor 14 and the analog signals from the electrocardiograph, blood pressure detector, and respiratory detector into digital signals, respectively, and transmits them to the computer 20; the computer 20 calculates and processes the received digital signals representing the exercise intensity of the load experiment of the subject to form real-time exercise intensity data of the subject, stores and displays the real-time exercise intensity data and transmits the data to the gating unit 18, calculates and processes the received digital signals reflecting the physiological condition of the subject to form physiological condition data of the subject, stores and displays the physiological condition data and transmits the physiological condition data to the gating unit 18; the subject observes the movement intensity displayed by the computer in real time, and adjusts the force application intensity according to the movement intensity displayed by the computer until the required movement intensity is reached; when the physiological condition data and the exercise intensity data of the subject received by the gating unit 18 reach the set threshold values, the gating unit 18 controls the magnetic resonance device 16 to perform dynamic scanning imaging; the magnetic resonance apparatus 16 transmits the digital signals of the scan results to the computer 20, and the computer 20 processes the received digital signals of the scan results to form magnetic resonance images for storage and display.

Claims

1. The magnetic resonance imaging load experiment system comprises magnetic resonance equipment (16), wherein the magnetic resonance equipment comprises a magnetic resonance scanning bed (16-1), and is characterized by further comprising a multifunctional load experiment motion device (15) for magnetic resonance imaging, a human body information detector (17), a gating unit (18), an analog/digital converter (19) and a computer (20);

the multifunctional load experiment movement device (15) for magnetic resonance imaging consists of a fixed plate (1), a foot placement and movement mechanism (2), a sliding guide rail assembly, a movement transmission assembly and an air pressure sensor (14); the foot placement and movement mechanism (2) comprises an ankle placement piece (3), a foot pedal (4), a limiting plate (5), a limiting bolt (6) and a sliding base (8); the ankle placing piece (3) mainly comprises a supporting table (3-2) and an ankle placing groove (3-1) positioned on the supporting table, and the bottom surface of the supporting table is fixedly connected with the sliding base (8); the lower sections of the two side surfaces of the foot pedal (4) are respectively provided with a first limit hole (4-1) which is matched with the limit bolt (6) in size, the foot pedal is positioned at one end of the ankle placing groove (3-1), and the lower end of the foot pedal is hinged with the supporting table (3-2); the two limiting plates (5) are respectively provided with a plurality of second limiting holes (5-1), the second limiting holes Kong Xiangge are distributed in an arc shape at intervals, correspond to the height positions of the first limiting holes (4-1) and are matched with the size of the limiting bolts (6), and the two limiting plates are respectively positioned on two sides of the foot pedal (4) and fixedly connected with the supporting table; the sliding guide rail assembly consists of two sliding guide rails (9) and two sliding limiting parts (10), wherein the number of the sliding guide rails (9) is at least two, and the sliding limiting parts (10) are bolt and buckle assemblies or bolt and nut assemblies; the motion transmission component is an air bag (7) and piston cylinder combination; the two sliding guide rails (9) are arranged on the fixed plate (1) in parallel, and the interval between the two sliding guide rails is matched with the width of the sliding base (8); the foot placement and movement mechanism (2) is placed on the fixed plate (1) and is positioned between the two sliding guide rails (9), and a sliding base (8) in the foot placement and movement mechanism is combined with the two sliding guide rails (9) to form a sliding pair; the sliding limiting piece (10) is used for fixing the foot placement and movement mechanism at a required position or limiting the foot placement and movement mechanism in a required movement range through combining with third limiting holes (9-1) arranged on the two sliding guide rails; the air bag (7) is arranged at the upper part of the surface of the foot pedal (4) facing the ankle placing groove (3-1), a piston rod (11) in the piston cylinder assembly is hinged with the surface of the foot pedal (4) facing away from the ankle placing groove (3-1), and the bottom end of the cylinder (12) is hinged with the fixed plate (1); the signal receiving end of the air pressure sensor (14) is respectively combined with air inlets arranged on the wall of the air bag (7) and the wall of the air cylinder (12);

An ankle placement part (3) in the multifunctional load experiment moving device (15) for magnetic resonance imaging is combined with the magnetic resonance scanning bed (16-1), and an air pressure sensor (14) in the multifunctional load experiment moving device (15) for magnetic resonance imaging is electrically connected with the analog-to-digital converter (19) to convert an acquired air pressure signal representing the load experiment moving intensity of a subject into an analog signal and transmit the analog signal to the analog-to-digital converter (19);

the human body information detector (17) is electrically connected with the analog-to-digital converter (19) and transmits the detected analog signal reflecting the physiological condition of the subject to the analog-to-digital converter (19);

the computer (20) is electrically connected with the analog-to-digital converter (19), the magnetic resonance equipment (16) and the gating unit (18) respectively; an analog-to-digital converter (19) converts an analog signal from the air pressure sensor (14) and an analog signal from the human body information detector (17) into digital signals, respectively, and transmits the digital signals to a computer (20); the computer (20) calculates and processes the received digital signals representing the exercise intensity of the load experiment of the subject to form real-time exercise intensity data of the subject, stores and displays the data and sends the data to the gating unit (18), calculates and processes the received digital signals reflecting the physiological condition of the subject to form physiological condition data of the subject, stores and displays the data and sends the data to the gating unit (18); the computer (20) is also used for controlling the magnetic resonance equipment (16) to carry out magnetic resonance scanning, receiving a scanning result digital signal input by the magnetic resonance equipment, and processing the received scanning result digital signal to form a magnetic resonance image for storage and display;

The gating unit (18) is electrically connected with the magnetic resonance equipment (16), the gating unit is provided with a physiological condition data threshold value and a motion intensity data threshold value of the subject, and when the physiological condition and the motion intensity data of the subject input by the computer (20) reach the threshold value, the gating unit generates a gating digital signal and outputs the gating digital signal to the magnetic resonance equipment (16) to control the magnetic resonance equipment (16) to perform magnetic resonance scanning.

2. The magnetic resonance imaging load experiment system according to claim 1, characterized in that the ankle placing groove (3-1) in the multifunctional load experiment motion device (15) for magnetic resonance imaging is detachably connected with the supporting table (3-2) through screws.

3. The magnetic resonance imaging load experiment system according to claim 1, characterized in that the ankle placing piece (3) in the multifunctional load experiment movement device (15) for magnetic resonance imaging further comprises two supporting plates (13), wherein the two supporting plates are respectively positioned at two sides of the ankle placing groove (3-1) and are arranged on the sliding base (8), and two side surfaces of the ankle placing groove (3-1) are respectively detachably connected with the two supporting plates through screws.

4. A magnetic resonance imaging load experiment system according to any one of claims 1 to 3, characterized in that the fixing plate (1), the foot placement and movement mechanism, the sliding guide rail assembly and the movement transmission assembly in the multifunctional load experiment movement device (15) for magnetic resonance imaging are made of acetal resin, polytetrafluoroethylene or rubber.

5. The magnetic resonance imaging load experiment system according to claim 1, characterized in that the human body information detector (17) is at least one of an electrocardiographic detector, a blood pressure detector and a respiratory detector.

6. Use of a magnetic resonance imaging stress test system according to any of the claims 1 to 5, characterized in that the system is used for the training of a shank stress test exercise and for magnetic resonance scanning imaging, operated as follows:

(1) allowing the subject to lie on his back on the magnetic resonance scanning bed (16-1), placing his test leg in a leg support groove of the magnetic resonance scanning bed, winding a flexible magnetic resonance coil, and entering the magnet in a leg advanced manner;

(2) taking down an air bag (7) in the multifunctional load experiment movement device for magnetic resonance imaging, filling compressed air into a cylinder (12) of the piston cylinder assembly to stop the air filling after the piston is positioned at the top end of the cylinder, and combining a signal receiving end of an air pressure sensor (14) with an air inlet hole arranged on the wall of the cylinder (12);

(3) placing the feet of the tested legs on ankle placing grooves (3-1) of a multifunctional load experiment movement device for magnetic resonance imaging, adjusting the rotation range of the foot pedal (4), controlling the rotation range to be within the range that the foot surface of the tested can pedal the foot pedal (4), combining two limiting bolts (6) with a corresponding group of second limiting holes (5-1) on two limiting plates (5) respectively, combining two limiting bolts (6) with another corresponding group of second limiting holes (5-1) on the two limiting plates (5) respectively, and limiting the rotation of the foot pedal (4) to the determined rotation range; then the foot placement and movement mechanism is fixed at the position through the combination of the sliding limiting piece (10) and a third limiting hole (9-1) arranged on the sliding guide rail (9);

(4) Informing a subject of the required exercise intensity, then enabling the subject to pedal the foot pedal (4) to enable the foot pedal to rotate around the hinge shaft of the foot pedal to reciprocate between the two groups of second limiting holes, so that the air pressure in the air cylinder (12) changes, the air pressure sensor (14) converts an acquired air pressure signal representing the experimental exercise intensity of the load of the lower leg of the subject into an analog signal and transmits the analog signal to the analog-to-digital converter (19), and the analog-to-digital converter (19) converts the analog signal from the air pressure sensor (14) into a digital signal and transmits the digital signal to the computer (20); the computer (20) calculates and processes the received digital signals representing the experimental exercise intensity of the calf load of the subject to form real-time exercise intensity data of the calf of the subject to be stored and displayed, the subject observes the exercise intensity displayed by the computer in real time, and adjusts the intensity of pedaling exercise according to the exercise intensity displayed by the computer until the required exercise intensity is reached;

during the calf load experiment exercise training, the computer (20) controls the magnetic resonance equipment (16) to perform resting state or/and equidistant state magnetic resonance scanning imaging according to the requirement;

when dynamic scanning imaging is needed, the human body information detector (17) is led to the subject, and the magnetic resonance equipment (16) is controlled by the gating unit to perform dynamic scanning imaging;

The magnetic resonance apparatus (16) transmits the digital signals of the scan results to the computer (20), and the computer (20) processes the received digital signals of the scan results to form magnetic resonance images for storage and display.

7. Use of a magnetic resonance imaging stress test system according to any of the claims 1 to 5, characterized in that the system is used for thigh stress test exercise training and for magnetic resonance scanning imaging, operated as follows:

(3) placing the foot of a tested leg on an ankle placing groove (3-1) of a multifunctional load experiment movement device for magnetic resonance imaging, rotating a foot pedal (4), inserting a limiting bolt (6) into a second limiting hole (5-1) arranged on a limiting plate and a first limiting hole (4-1) arranged on the side surface of the foot pedal, fixing the foot pedal, adjusting the sliding range of a foot placing and movement mechanism along a sliding guide rail (9), controlling the sliding range to be in a range in which the foot surface of the tested person can vertically apply force to the foot pedal (4), and limiting the foot placing and movement mechanism to be in a determined sliding range through the combination of two or two groups of sliding limiting pieces (10) and a third limiting hole (9-1) arranged on the sliding guide rail (9);

(4) Informing the subject of the required movement intensity, then enabling the subject to apply force to the foot pedal (4), enabling the foot placement and movement mechanism to slide in a reciprocating translation manner along the sliding guide rail (9) within a determined range, so that the gas pressure in the gas cylinder (12) is changed, converting the acquired gas pressure signal representing the thigh load experimental movement intensity of the subject into an analog signal by the gas pressure sensor (14) and transmitting the analog signal to the analog/digital converter (19), and converting the analog signal from the gas pressure sensor (14) into a digital signal by the analog/digital converter (19) and transmitting the digital signal to the computer (20); the computer (20) calculates and processes the received digital signals representing the thigh load experiment exercise intensity of the subject to form thigh real-time exercise intensity data of the subject to be stored and displayed, the subject observes the exercise intensity displayed by the computer in real time, and adjusts the force application intensity of the foot pedal (4) according to the exercise intensity displayed by the computer until the required exercise intensity is reached;

during thigh load experiment exercise training, the computer (20) controls the magnetic resonance equipment (16) to perform resting state or/and equidistant state magnetic resonance scanning imaging according to the requirement;

8. Use of a magnetic resonance imaging loadometer system according to any one of claims 1 to 5 for the foot loadometer exercise training and magnetic resonance scanning imaging, as follows:

(1) allowing a subject to lie on the back on the magnetic resonance scanning bed (16-1), placing the tested legs of the subject in leg support grooves of the magnetic resonance scanning bed, entering a magnet in a leg advanced mode, and winding a flexible magnetic resonance coil on the foot;

(2) filling compressed air into an air bag (7) in the multifunctional load experiment movement device for magnetic resonance imaging, stopping filling when the air bag is in a filling state, and combining a signal receiving end of an air pressure sensor (14) with an air inlet hole arranged on the wall of the air bag (7);

(3) placing the foot of a tested leg on an ankle placing groove (3-1) of a multifunctional load experiment movement device for magnetic resonance imaging by a subject, rotating a foot pedal (4) to enable the foot pedal to be in contact with the foot surface of the subject, inserting a limiting bolt (6) into a second limiting hole (5-1) arranged on the limiting plate and a first limiting hole (4-1) arranged on the side surface of the foot pedal, fixing the foot pedal at the position, and fixing the foot placing and movement mechanism through the combination of two or two groups of sliding limiting pieces (10) and a third limiting hole (9-1) arranged on a sliding guide rail (9);

(4) Informing the subject of the required exercise intensity, then bending and squeezing the air bag (7) by the toe of the subject, so that the air pressure in the air bag (7) is changed, converting the acquired air pressure signal representing the experimental exercise intensity of the foot load of the subject into an analog signal by the air pressure sensor (14) and transmitting the analog signal to the analog/digital converter (19), and converting the analog signal from the air pressure sensor (14) into a digital signal by the analog/digital converter (19) and transmitting the digital signal to the computer (20); the computer (20) calculates and processes the received digital signals representing the experimental exercise intensity of the foot load of the subject, forms the real-time exercise intensity data of the foot of the subject to be stored and displayed, the subject observes the exercise intensity displayed by the computer in real time, and adjusts the extrusion force intensity of the air bag (7) according to the exercise intensity displayed by the computer until the required exercise intensity is reached;

during the foot load experiment exercise training, the computer (20) controls the magnetic resonance equipment (16) to perform resting state or/and equidistant state magnetic resonance scanning imaging according to the requirement;

9. Use of a magnetic resonance imaging stress test system according to any of the claims 1 to 5, characterized in that the system is used for cardiac stress test exercise training and for magnetic resonance scanning imaging, operated as follows:

(1) a human body information detector (17) is led on the body of the subject, then the subject is supine on a magnetic resonance scanning bed, a magnetic resonance special coil is placed on the chest part of the subject, and the subject enters a magnet in a head advanced mode;

(2) selecting and referring to the calf load experimental exercise or the thigh load experimental exercise for training, and informing the subject of the required exercise intensity, an analog/digital converter (19) respectively converting an analog signal from the air pressure sensor (14) and an analog signal from the human body information detector (17) into digital signals for transmission to a computer (20); the computer (20) calculates and processes the received digital signals representing the exercise intensity of the load experiment of the subject to form real-time exercise intensity data of the subject, stores and displays the data and sends the data to the gating unit (18), calculates and processes the received digital signals reflecting the physiological condition of the subject to form physiological condition data of the subject, stores and displays the data and sends the data to the gating unit (18); the subject observes the movement intensity displayed by the computer in real time, and adjusts the force application intensity according to the movement intensity displayed by the computer until the required movement intensity is reached; when the physiological condition data and the exercise intensity data of the subjects received by the gating unit (18) reach a set threshold value, the gating unit (18) controls the magnetic resonance equipment (16) to perform dynamic scanning imaging; the magnetic resonance apparatus (16) transmits the digital signals of the scan results to the computer (20), and the computer (20) processes the received digital signals of the scan results to form magnetic resonance images for storage and display.