CN108014287A - A kind of effervesce bacteria inhibition tablet and preparation method thereof - Google Patents
A kind of effervesce bacteria inhibition tablet and preparation method thereof Download PDFInfo
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- CN108014287A CN108014287A CN201810104877.3A CN201810104877A CN108014287A CN 108014287 A CN108014287 A CN 108014287A CN 201810104877 A CN201810104877 A CN 201810104877A CN 108014287 A CN108014287 A CN 108014287A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/234—Cnidium (snowparsley)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/904—Stemonaceae (Stemona family), e.g. croomia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
The invention discloses a kind of effervesce bacteria inhibition tablet, it is characterised in that including following component；Chlorhexidine acetate, citric acid, sodium acid carbonate, lactic acid bacteria bacterium powder, kuh-seng powder, tuber of stemona powder, frutus cnidii powder, safflower powder, Cortex Phellodendri powder, aloe powder, TM600（Lubricant）, middle medicinal-flavor and water, this kind of effervesce bacteria inhibition tablet and preparation method thereof, not only high effect nontoxic, and harmful effect will not be produced to human body and article in use, there can be killing germ by the solid bacteria inhibition tablet being mixed into, the bacteriostasis rate of staphylococcus aureus is more than or equal to 50%, the bacteriostasis rate of Escherichia coli is more than or equal to 50%, the bacteriostasis rate of Candida albicans is more than or equal to 50%, it is set effectively to suppress pathogen growth, reduce germ infringement, protect vagina, achieve the purpose that bacteriostasis antibiosis, and the antibacterial sheet weight of this kind of effervesce is at 0.65 gram, weight is minimum, the sense of discomfort of patient can be effectively reduced during use.
Description
Technical field
The present invention relates to pharmaceutical technology field, more particularly, to a kind of effervesce bacteria inhibition tablet and preparation method thereof.
Background technology
Chlorhexidine acetate is also Robenidine Roripa, chlorhexidine acetate, Chlorhexidine, double benzyl chloride chlorhexidine, for sun
Ionic surface active agent, has a broad antifungal spectrum have killing effect to most Grain-positives and negative bacteria, also have to Pseudomonas aeruginosa
Effect.For remote holder of performing the operation, skin, planing surface and sterilization of instruments, the bactericidal effect methods of investigation chlorhexidine acetate disinfectant：Using
Paper disk method observes the size of inhibition zone, investigates influence of the concentration of alcohol to bactericidal effect, the bactericidal effect of more each prescription, and make
Skin degerming effect field test results：Said preparation has preferable killing effect to staphylococcus aureus, Escherichia coli；
Selected 3 kinds of concentration of alcohol（60%,70%,75%）Bactericidal effect is influenced little；It is right after 3 min of disinfectant stock solution effect
The natural killing rate of skin surface bacterium conclusions more than 99%：Chlorhexidine acetate spraying sterilizing agent has wide spectrum, quick-acting, quick-drying
The characteristics of, it is more satisfied skin antiseptic.
Sodium acid carbonate, chemical formula NaHCO3, it is commonly called as sodium bicarbonate.White fine crystals, solubility in water are less than carbonic acid
Sodium.It is also a kind of chemicals for industrial use, and more than 50 DEG C beginnings of solid, which are gradually decomposed, generates sodium carbonate, carbon dioxide and water, and 270
DEG C when decompose completely, sodium acid carbonate is highly basic neutralized with weak acid after the acid salt that generates, alkalescent is presented when being dissolved in water.This characteristic
It can make it as the leavening agent in food product making process.Sodium acid carbonate can remain sodium carbonate after effect, using can excessively make into
Product have an alkali taste, and sodium acid carbonate is white crystal, or opaque monoclinic system grain.Proportion 2.15.It is odorless, nontoxic, taste is salty,
It is water-soluble, it is slightly soluble in ethanol.It is dissolved in 10 parts of water at 25 DEG C, about 18 DEG C of whens are dissolved in 12 parts of water.Its aqueous solution is in micro- because of hydrolysis
Alkalescence, property is stablized in room temperature, is heated and easily decomposes, and gradually decomposition, carbon dioxide is lost at 270 DEG C completely more than 50 DEG C,
It is unchanged in dry air, the slow deliquescence in humid air.
Citric acid is a kind of important organic acid, also known as citric acid, and clear crystal, often contains a molecular crystalline water, odorless, has
Very strong tart flavour, it is soluble easily in water.Its calcium salt is more soluble than in hot water in cold water, this property is commonly used to be identified and isolated from lemon
Acid.Suitable temperature is controlled to obtain anhydrous citric acid during crystallization.There is extremely more purposes in industry, grocery trade, makeup industry etc.,
Citric acid is also known as Chinese holly edge acid, chemical name 2- hydroxy propanes -1,2,3- tricarboxylic acids.According to the difference of its water content, it is divided into a water
Citric acid and anhydrous citric acid.The purposes of citric acid is very extensive, accounts for more than the 75% of output for food industry, can be used as
The acid of food, antioxidant, pH adjusting agent, in the food such as cold drink, jam, fruit and cake.For medicine
Industry accounts for 10% or so, is mainly used as anticoagulant, antiacid, flavouring, cosmetics etc..It is left that 15% is accounted for for chemical industry etc.
The right side, as buffer, complexing agent, metal cleaner, mordant, gelling agent, toner etc..Electronics, weaving, oil, leather,
Have very wide in the industrial circles such as building, photography, plastics, casting and ceramics, but bacteria inhibition tablet in the prior art closes
It is most of in agent that effective antibacterial and bactericidal effect can not still carry out vagina using above-mentioned material.
The content of the invention
The technical problem to be solved in the present invention is overcome the defects of existing, there is provided a kind of effervesce bacteria inhibition tablet and its preparation side
Method, so as to solve the above problems.
To achieve the above object, the present invention provides following technical solution：A kind of effervesce bacteria inhibition tablet, including following component；Vinegar
Sour Chlorhexidine, citric acid, sodium acid carbonate, lactic acid bacteria bacterium powder, kuh-seng powder, tuber of stemona powder, frutus cnidii powder, safflower powder, Cortex Phellodendri powder, aloe
Powder, TM600（Lubricant）, middle medicinal-flavor and water.
As a preferred technical solution of the present invention, the chlorhexidine acetate, citric acid, sodium acid carbonate, lactic acid bacteria bacterium
Powder, kuh-seng powder, tuber of stemona powder, frutus cnidii powder, safflower powder, Cortex Phellodendri powder, aloe powder, TM600（Lubricant）, middle medicinal-flavor and water mixing
Simple grain total weight of tablet is 0.65 gram.
As a preferred technical solution of the present invention, the chlorhexidine acetate accounts for the 0.8% of total content, the citric acid
The 30% of total content is accounted for, the sodium acid carbonate accounts for the 50% of total content, and the lactic acid bacteria bacterium powder accounts for the 11% of total content, the kuh-seng
Powder, tuber of stemona powder, frutus cnidii powder, safflower powder, Cortex Phellodendri powder and aloe powder account for the 1% of total content, the TM600（Lubricant）Account for total
The 0.005% of content, the middle medicinal-flavor account for the 0.01% of total content, and the water accounts for the 2.185% of total content, total content 100%.
A kind of effervesce bacteria inhibition tablet and preparation method thereof, comprises the following steps；
Step 1；The chlorhexidine acetate, citric acid, sodium acid carbonate, lactic acid bacteria bacterium powder, kuh-seng powder, tuber of stemona powder, frutus cnidii powder,
Safflower powder, Cortex Phellodendri powder, aloe powder, TM600（Lubricant）It is added to middle medicinal-flavor in the water and carries out uniform stirring, contains it
Amount is evenly distributed；
Step 2；To the chlorhexidine acetate, citric acid, sodium acid carbonate, lactic acid bacteria bacterium powder, kuh-seng powder, tuber of stemona powder, frutus cnidii
Powder, safflower powder, Cortex Phellodendri powder, aloe powder, TM600（Lubricant）, middle medicinal-flavor and aqueous mixtures are into shaped solid.
As a preferred technical solution of the present invention, in step 1 and step 2, the operation of step 1 is first carried out,
The operation of step 2 is carried out, and the water is plasma water.
Compared with prior art, the beneficial effects of the invention are as follows：This kind of effervesce bacteria inhibition tablet and preparation method thereof, not only efficiently
It is nontoxic, and in use harmful effect will not be produced to human body and article, pass through chlorhexidine acetate, citric acid, carbonic acid
Hydrogen sodium, lactic acid bacteria bacterium powder, kuh-seng powder, tuber of stemona powder, frutus cnidii powder, safflower powder, Cortex Phellodendri powder, aloe powder, TM600（Lubricant）, in
The solid bacteria inhibition tablet that medicinal-flavor and water are mixed into can have killing germ, and the bacteriostasis rate of staphylococcus aureus is more than or equal to 50%,
The bacteriostasis rate of Escherichia coli is more than or equal to 50%, and the bacteriostasis rate of Candida albicans is more than or equal to 50%, it is effectively suppressed germ
Growth, reduces germ infringement, protects vagina, achieve the purpose that bacteriostasis antibiosis, and the antibacterial sheet weight of this kind of effervesce is 0.65
Gram, weight is minimum, and the sense of discomfort of patient can be effectively reduced during use.
Embodiment
Technical solution in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is only
It is part of the embodiment of the present invention, instead of all the embodiments, based on the embodiments of the present invention, ordinary skill people
Member's all other embodiments obtained without making creative work, belong to the scope of protection of the invention.
The present invention provides a kind of technical solution：A kind of effervesce bacteria inhibition tablet, including following component；Chlorhexidine acetate, citric acid,
Sodium acid carbonate, lactic acid bacteria bacterium powder, kuh-seng powder, tuber of stemona powder, frutus cnidii powder, safflower powder, Cortex Phellodendri powder, aloe powder, TM600（Lubrication
Agent）, middle medicinal-flavor and water.
Chlorhexidine acetate, citric acid, sodium acid carbonate, lactic acid bacteria bacterium powder, kuh-seng powder, tuber of stemona powder, frutus cnidii powder, safflower powder,
Cortex Phellodendri powder, aloe powder, TM600（Lubricant）, middle medicinal-flavor and water mixing simple grain total weight of tablet be 0.65 gram.
Chlorhexidine acetate accounts for the 0.8% of total content, and the citric acid accounts for the 30% of total content, and the sodium acid carbonate accounts for total content
50%, the lactic acid bacteria bacterium powder accounts for the 11% of total content, the kuh-seng powder, tuber of stemona powder, frutus cnidii powder, safflower powder, Cortex Phellodendri powder and
Aloe powder accounts for the 1% of total content, the TM600（Lubricant）The 0.005% of total content is accounted for, the middle medicinal-flavor accounts for total content
0.01%, the water accounts for the 2.185% of total content, total content 100%.
A kind of effervesce bacteria inhibition tablet and preparation method thereof, comprises the following steps；
Step 1；Chlorhexidine acetate, citric acid, sodium acid carbonate, lactic acid bacteria bacterium powder, kuh-seng powder, tuber of stemona powder, frutus cnidii powder, safflower
Powder, Cortex Phellodendri powder, aloe powder, TM600（Lubricant）It is added to middle medicinal-flavor in the water and carries out uniform stirring, makes its content point
Cloth is uniform；
Step 2；It is Dichlorodiphenyl Acetate Chlorhexidine, citric acid, sodium acid carbonate, lactic acid bacteria bacterium powder, kuh-seng powder, tuber of stemona powder, frutus cnidii powder, red
Pollen, Cortex Phellodendri powder, aloe powder, TM600（Lubricant）, middle medicinal-flavor and aqueous mixtures are into shaped solid.
In step 1 and step 2, first carry out step 1 operation, carry out step 2 operation, and the water for etc.
Ionized water.
Concrete principle：In use, improving upgrading by being formulated, chlorhexidine acetate, citric acid, sodium acid carbonate, lactic acid are used
Bacterium bacterium powder, kuh-seng powder, tuber of stemona powder, frutus cnidii powder, safflower powder, Cortex Phellodendri powder, aloe powder, TM600（Lubricant）, middle medicinal-flavor and water
The solid bacteria inhibition tablet being mixed into can have killing germ, and the bacteriostasis rate of staphylococcus aureus is more than or equal to 50%, Escherichia coli
Bacteriostasis rate is more than or equal to 50%, and the bacteriostasis rate of Candida albicans is more than or equal to 50%, hence it is evident that improves bactericidal and bacteriostatic effect, makes its effective
Suppression pathogen growth, reduce germ infringement, protect vagina, achieve the purpose that bacteriostasis antibiosis, and this kind of effervesce bacteria inhibition tablet
For weight at 0.65 gram, weight is minimum, and the sense of discomfort of patient can be effectively reduced during use.
This kind of effervesce bacteria inhibition tablet and preparation method thereof, not only high effect nontoxic, but also in use will not to human body and
Article produces harmful effect, passes through chlorhexidine acetate, citric acid, sodium acid carbonate, lactic acid bacteria bacterium powder, kuh-seng powder, tuber of stemona powder, cnidium monnieri
Sub- powder, safflower powder, Cortex Phellodendri powder, aloe powder, TM600（Lubricant）, the solid bacteria inhibition tablet that is mixed into of middle medicinal-flavor and water can have
Germ is killed, the bacteriostasis rate of staphylococcus aureus is more than or equal to 50%, and the bacteriostasis rate of Escherichia coli is more than or equal to 50%, and white is read
The bacteriostasis rate of pearl bacterium is more than or equal to 50%, it is effectively suppressed pathogen growth, reduces germ infringement, protects vagina, reach
The purpose of bacteriostasis antibiosis, and the antibacterial sheet weight of this kind of effervesce, at 0.65 gram, weight is minimum, and trouble can be effectively reduced during use
The sense of discomfort of person.
Finally it should be noted that：The foregoing is only a preferred embodiment of the present invention, is not intended to limit the invention,
Although the present invention is described in detail with reference to the foregoing embodiments, for those skilled in the art, it still may be used
To modify to the technical solution described in foregoing embodiments, or equivalent substitution is carried out to which part technical characteristic,
Within the spirit and principles of the invention, any modification, equivalent replacement, improvement and so on, should be included in the present invention's
Within protection domain.
Claims (5)
1. a kind of effervesce bacteria inhibition tablet, it is characterised in that including following component；Chlorhexidine acetate, citric acid, sodium acid carbonate, lactic acid
Bacterium bacterium powder, kuh-seng powder, tuber of stemona powder, frutus cnidii powder, safflower powder, Cortex Phellodendri powder, aloe powder, TM600（Lubricant）, middle medicinal-flavor and
Water；.
2. a kind of effervesce bacteria inhibition tablet according to claim 1, it is characterised in that the chlorhexidine acetate, citric acid, carbonic acid
Hydrogen sodium, lactic acid bacteria bacterium powder, kuh-seng powder, tuber of stemona powder, frutus cnidii powder, safflower powder, Cortex Phellodendri powder, aloe powder, TM600（Lubricant）, in
Medicinal-flavor and water mixing simple grain total weight of tablet are 0.65 gram.
3. a kind of effervesce bacteria inhibition tablet according to claim 1, it is characterised in that the chlorhexidine acetate accounts for total content
0.8%, the citric acid accounts for the 30% of total content, and the sodium acid carbonate accounts for the 50% of total content, and the lactic acid bacteria bacterium powder accounts for total content
11%, the kuh-seng powder, tuber of stemona powder, frutus cnidii powder, safflower powder, Cortex Phellodendri powder and aloe powder account for the 1% of total content, described
TM600（Lubricant）The 0.005% of total content is accounted for, the middle medicinal-flavor accounts for the 0.01% of total content, and the water accounts for total content
2.185%, total content 100%.
4. a kind of its preparation method of effervesce bacteria inhibition tablet, it is characterised in that comprise the following steps；
Step 1；The chlorhexidine acetate, citric acid, sodium acid carbonate, lactic acid bacteria bacterium powder, kuh-seng powder, tuber of stemona powder, frutus cnidii powder,
Safflower powder, Cortex Phellodendri powder, aloe powder, TM600（Lubricant）It is added to middle medicinal-flavor in the water and carries out uniform stirring, contains it
Amount is evenly distributed；
Step 2；To the chlorhexidine acetate, citric acid, sodium acid carbonate, lactic acid bacteria bacterium powder, kuh-seng powder, tuber of stemona powder, frutus cnidii
Powder, safflower powder, Cortex Phellodendri powder, aloe powder, TM600（Lubricant）, middle medicinal-flavor and aqueous mixtures are into shaped solid.
5. a kind of effervesce bacteria inhibition tablet according to claim 4, it is characterised in that in step 1 and step 2, first carry out
The operation of step 1, is carrying out the operation of step 2, and the water is plasma water.
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Cited By (4)
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| CN109646349A (en) * | 2018-12-29 | 2019-04-19 | 珠海横琴亘德生物科技有限公司 | A kind of Chinese medicine composition for cleaning-nursing at women secret |
| CN109663099A (en) * | 2019-01-17 | 2019-04-23 | 申庆亮 | A kind of bacteriostatic agent and preparation method thereof can be used for assisting in the treatment of lymphedema |
| CN111053893A (en) * | 2019-12-30 | 2020-04-24 | 重庆宫妙生物科技有限公司 | Antibacterial effervescent tablet and preparation method thereof |
| CN111956792A (en) * | 2020-09-01 | 2020-11-20 | 田兰 | Preparation method of Yizhi peptide bacteriostatic tablet |
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