CN108014250A - A kind of blood pressure lowering composition and preparation method thereof - Google Patents

A kind of blood pressure lowering composition and preparation method thereof Download PDF

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Publication number
CN108014250A
CN108014250A CN201810012363.5A CN201810012363A CN108014250A CN 108014250 A CN108014250 A CN 108014250A CN 201810012363 A CN201810012363 A CN 201810012363A CN 108014250 A CN108014250 A CN 108014250A
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parts
blood pressure
pressure lowering
honey
lowering composition
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顾文革
朱殿章
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/24—Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482—Cassia, e.g. golden shower tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/62—Nymphaeaceae (Water-lily family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/64—Orobanchaceae (Broom-rape family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734—Crataegus (hawthorn)
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals

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Abstract

The invention discloses a kind of blood pressure lowering composition and preparation method thereof.The blood pressure lowering composition includes the raw material of following parts by weight：14 parts of ginkgo leaf, 26 parts of bluish dogbane, 13 parts of cassia seed, 13 parts of lotus leaf, 13 parts of Radix Liriopes, 12 parts of the membrane of a chicken's gizzard, 13 parts of spina date seed, 12 parts of leaves of Hawthorn, 12 parts of dark plum, 0.1 1 parts of saline cistanche.The blood pressure lowering composition of the present invention, which has, to be depressured, clears liver and improve vision, detoxifying and relieve inflammation or internal heat and other effects；Security is good, and long-term use has no adverse reaction, liver-kidney tonifying；Preparation process is simple, uniform in quality is stablized, and has good producing feasibility and application value.

Description

A kind of blood pressure lowering composition and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine composition, is specifically a kind of blood pressure lowering composition and preparation method thereof.
Background technology
Hypertension be it is a kind of characterized by angiosthenia raises, can with heart, blood vessel, brain and kidney and other organs feature or The systemic disease of organic change, it has point of essential hypertension and secondary hypertension, is a kind of common disease and multiple Disease.Essential hypertension, which is called, does high blood pressure, be using blood pressure rise as main clinical manifestation the independence of etiology undetermined Disease, accounts for more than the 90% of hypertensive patient.Secondary hypertension, which is called, does symptomatic hypertension, in the disease of such middle hypertension Because being one of performance of certain disease clearly.The general onset of this disease is slow, and patient's early stage is often asymptomatic, or only dizzy, head Bitterly, the symptom such as palpitaition, tinnitus, seemingly a kind of independent disease, actually triggers the one of the heart, the cerebrovascular and nephropathy A important hazards, if malpractice will lesion become more serious headstroke, myocardial infarction and renal failure Deng these common hypertension complications.
The chemotherapy to hypertension is by the World Health Organization and China using ACEI hypotensor things etc. at present《High blood Press treatment guidelines》It is classified as a line antihypertensive drugs, but there are serious side effect, occurs irritation dry cough after such as taking, can be with Dry throat, pharynx itch, be uncomfortable in chest, night and lie down postemphasis, or occur fash, itch, dysgeusia, albuminuria, granulocyte reduce Deng adverse reaction.No matter the common oral or intravenous administration of Macrocyclolactone lactone kind medicine, prolonged application or dosage are excessive and cause liver Infringement, Auditory nerve impairment cause deafness etc..Western medicine not only has very big side effect in the treatment, but also has larger dependence Property, it is necessary to long-term use of, and the most important is that decompression is unstable, and during taking medicine, blood pressure can be fluctuated, it is impossible to Old complaint is dispelled, once being discontinued, blood pressure bounce amplitudes are big, aggravated patient body burden.
In the Traditional Chinese Medicine in China, generally by hypertension belong to " dizziness ", " headache ", " liver-yang ", " liver wind ", " in The illness category such as wind ", be mainly manifested in type of deficiency of YIN leading to hyper activity of YANG, liver wind agitation, the yin-yang deficiency, insufficiency of both the spleen and the kindey, retention of phlegmatic dampness, in hemostasis Resistance etc..Mainly treated with the medicine such as calming the liver, promoting blood circulation and removing blood stasis.Although existing Chinese medicine has the effect of certain, deposit Work slow, therapeutic effect unobvious the defects of.
The content of the invention
It is an object of the invention to provide a kind of blood pressure lowering composition and preparation method thereof, to solve to carry in above-mentioned background technology The problem of going out.
To achieve the above object, the present invention provides following technical solution：
A kind of blood pressure lowering composition, includes the raw material of following parts by weight：1-4 parts of ginkgo leaf, 2-6 parts of bluish dogbane, cassia seed 1-3 Part, 1-3 parts of lotus leaf, 1-3 parts of Radix Liriopes, 1-2 parts of the membrane of a chicken's gizzard, 1-3 parts of spina date seed, 1-2 parts of leaves of Hawthorn, 1-2 parts of dark plum, saline cistanche 0.1-1 parts.
As the further scheme of the present invention：Include the raw material of following parts by weight：2 parts of ginkgo leaf, 3 parts of bluish dogbane, certainly 1 part of pine torch, 2 parts of lotus leaf, 2 parts of Radix Liriopes, 1.2 parts of the membrane of a chicken's gizzard, 2 parts of spina date seed, 1.4 parts of leaves of Hawthorn, 1.5 parts of dark plum, saline cistanche 0.5 part.
As the further scheme of the present invention：Further include honey.
A kind of preparation method of blood pressure lowering composition, comprises the following steps：（1）Each raw material is weighed according to above-mentioned formula, it is spare； （2）By the ginkgo leaf got ready, bluish dogbane, cassia seed, lotus leaf, Radix Liriopes, the membrane of a chicken's gizzard, spina date seed, leaves of Hawthorn, dark plum and saline cistanche Respectively after drying, grinding, medicinal powder is mixed to get；（3）Honey is boiled, first endures boiling with high heat, then 10- is boiled with slow boiling 20min；（4）The honey boiled is poured into the medicinal powder in container with spoon, while is stirred with chopsticks in medicinal powder, is finished down bee After honey, with the both hands after disinfection by medicinal powder and honey and for one；（5）Rubbing and ball, packaging.
As the further scheme of the present invention：The weight ratio of medicinal powder and honey is 1:（1-1.5）.
As the further scheme of the present invention：It it is 10g/ with ball specification.
Compared with prior art, the beneficial effects of the invention are as follows：
The blood pressure lowering composition of the present invention, which has, to be depressured, clears liver and improve vision, detoxifying and relieve inflammation or internal heat and other effects；Security is good, and long-term use is invariably Good reaction, liver-kidney tonifying；Preparation process is simple, uniform in quality is stablized, and has good producing feasibility and application value.
Embodiment
The technical solution of this patent is described in more detail with reference to embodiment.
Embodiment 1
A kind of blood pressure lowering composition, includes the raw material of following parts by weight：1 part of ginkgo leaf, 2 parts of bluish dogbane, 1 part of cassia seed, lotus leaf 1 Part, 1 part of Radix Liriopes, 1 part of the membrane of a chicken's gizzard, 1 part of spina date seed, 1 part of leaves of Hawthorn, 1 part of dark plum, 0.1 part of saline cistanche.Further include honey.
A kind of preparation method of blood pressure lowering composition, comprises the following steps：（1）Each raw material is weighed according to above-mentioned formula, it is spare； （2）By the ginkgo leaf got ready, bluish dogbane, cassia seed, lotus leaf, Radix Liriopes, the membrane of a chicken's gizzard, spina date seed, leaves of Hawthorn, dark plum and saline cistanche Respectively after drying, grinding, medicinal powder is mixed to get；（3）Boil honey, the weight ratio of medicinal powder and honey is 1:1, with high heat first Boiling is endured, then 10min is boiled with slow boiling；（4）The honey boiled is poured into the medicinal powder in container with spoon, while is existed with chopsticks Stirred in medicinal powder, after being finished down honey, with the both hands after disinfection by medicinal powder and honey and for one；（5）Rubbing and ball, packaging.With Ball specification is 10g/.
Embodiment 2
A kind of blood pressure lowering composition, includes the raw material of following parts by weight：4 parts of ginkgo leaf, 6 parts of bluish dogbane, 3 parts of cassia seed, lotus leaf 3 Part, 3 parts of Radix Liriopes, 2 parts of the membrane of a chicken's gizzard, 3 parts of spina date seed, 2 parts of leaves of Hawthorn, 2 parts of dark plum, 1 part of saline cistanche.Further include honey.
A kind of preparation method of blood pressure lowering composition, comprises the following steps：（1）Each raw material is weighed according to above-mentioned formula, it is spare； （2）By the ginkgo leaf got ready, bluish dogbane, cassia seed, lotus leaf, Radix Liriopes, the membrane of a chicken's gizzard, spina date seed, leaves of Hawthorn, dark plum and saline cistanche Respectively after drying, grinding, medicinal powder is mixed to get；（3）Boil honey, the weight ratio of medicinal powder and honey is 1:1.5, first use force Fire endures boiling, then boils 20min with slow boiling；（4）The honey boiled is poured into the medicinal powder in container with spoon, while uses chopsticks Stirred in medicinal powder, after being finished down honey, with the both hands after disinfection by medicinal powder and honey and for one；（5）Rubbing and ball, packaging. It it is 10g/ with ball specification.
Embodiment 3
A kind of blood pressure lowering composition, includes the raw material of following parts by weight：2 parts of ginkgo leaf, 3 parts of bluish dogbane, 1 part of cassia seed, lotus leaf 2 Part, 2 parts of Radix Liriopes, 1.2 parts of the membrane of a chicken's gizzard, 2 parts of spina date seed, 1.4 parts of leaves of Hawthorn, 1.5 parts of dark plum, 0.5 part of saline cistanche.Further include bee Honey.
A kind of preparation method of blood pressure lowering composition, comprises the following steps：（1）Each raw material is weighed according to above-mentioned formula, it is spare； （2）By the ginkgo leaf got ready, bluish dogbane, cassia seed, lotus leaf, Radix Liriopes, the membrane of a chicken's gizzard, spina date seed, leaves of Hawthorn, dark plum and saline cistanche Respectively after drying, grinding, medicinal powder is mixed to get；（3）Boil honey, the weight ratio of medicinal powder and honey is 1:1.2, first use force Fire endures boiling, then boils 15min with slow boiling；（4）The honey boiled is poured into the medicinal powder in container with spoon, while uses chopsticks Stirred in medicinal powder, after being finished down honey, with the both hands after disinfection by medicinal powder and honey and for one；（5）Rubbing and ball, packaging. It it is 10g/ with ball specification.
Embodiment 4
A kind of blood pressure lowering composition, includes the raw material of following parts by weight：2 parts of ginkgo leaf, 5 parts of bluish dogbane, 2.5 parts of cassia seed, lotus 1.3 parts of leaf, 1.5 parts of Radix Liriopes, 1.5 parts of the membrane of a chicken's gizzard, 2.3 parts of spina date seed, 1.6 parts of leaves of Hawthorn, 1.4 parts of dark plum, saline cistanche 0.8 Part.Further include honey.
A kind of preparation method of blood pressure lowering composition, comprises the following steps：（1）Each raw material is weighed according to above-mentioned formula, it is spare； （2）By the ginkgo leaf got ready, bluish dogbane, cassia seed, lotus leaf, Radix Liriopes, the membrane of a chicken's gizzard, spina date seed, leaves of Hawthorn, dark plum and saline cistanche Respectively after drying, grinding, medicinal powder is mixed to get；（3）Boil honey, the weight ratio of medicinal powder and honey is 1:1.3, first use force Fire endures boiling, then boils 12min with slow boiling；（4）The honey boiled is poured into the medicinal powder in container with spoon, while uses chopsticks Stirred in medicinal powder, after being finished down honey, with the both hands after disinfection by medicinal powder and honey and for one；（5）Rubbing and ball, packaging. It it is 10g/ with ball specification.
The present invention theoretical foundation be：
Ginkgo leaf：Ginkgo leaf, is the dried leaf of ginkgo.Autumn leaf harvests when still green, dry in time.Generally artificial cultivation.Plant Training area north to Liaoning, Nan Da Guangdong, from the east of Zhejiang, west reaches the ground such as Shaanxi, Gansu, southwest to Sichuan, Guizhou, Yunnan.Have It is promoting blood circulation and removing blood stasis, the effect of removing obstruction in channels to relieve pain, astringe the lung and relieving asthma, change turbid lipid-loweringing.For obstruction of collaterals by blood stasis, chest impediment and cardialgia, hemiplegia, the deficiency syndrome of the lung Cough and asthma, hyperlipidemia.
Bluish dogbane：Nickname bluish dogbane, bluish dogbane, red building etc., upright fruticuli is 1.5-3 meters high, general about 2 meters high, highest Up to 4 meters, with being grown on the chiltern on riverbank, gully, hillside, in Chinese Huaihe River, the Qinling Mountains, each province to the north of Kun Lun Mountain（Autonomous region）All There is bluish dogbane distribution, relieve inflammation or internal heat, be depressured, cardiac stimulant, diuresis.Control the effect such as heart disease.
Cassia seed：Legume Cassia or the dry mature seed of little Cassia tora, with its have improving eyesight work(and name it.Autumn Ripening fruits is harvested, is dried, lays seed, removes impurity.Cassia seed bitter, sweet, salty, cold nature, enters liver, kidney, large intestine channel；Profit Intestines defaecation, lipid-loweringing improving eyesight, treats constipation and hyperlipidemia, hypertension.Clear liver and improve vision, sharp water defaecation, there is laxative action, blood pressure lowering drop Blood fat.
The blood pressure lowering composition of the present invention, which has, to be depressured, clears liver and improve vision, detoxifying and relieve inflammation or internal heat and other effects；Security is good, long-term use of Have no adverse reaction, liver-kidney tonifying；Preparation process is simple, uniform in quality is stablized, and has good producing feasibility and application Value.
The better embodiment of this patent is explained in detail above, but this patent is not limited to above-mentioned embodiment party Formula, can also be on the premise of this patent objective not be departed from the knowledge that one skilled in the relevant art possesses Various changes can be made.

Claims (6)

1. a kind of blood pressure lowering composition, it is characterised in that include the raw material of following parts by weight：1-4 parts of ginkgo leaf, bluish dogbane 2-6 Part, 1-3 parts of cassia seed, 1-3 parts of lotus leaf, 1-3 parts of Radix Liriopes, 1-2 parts of the membrane of a chicken's gizzard, 1-3 parts of spina date seed, 1-2 parts of leaves of Hawthorn, dark plum 1-2 parts, 0.1-1 parts of saline cistanche.
2. blood pressure lowering composition according to claim 1, it is characterised in that include the raw material of following parts by weight：Ginkgo leaf 2 Part, 3 parts of bluish dogbane, 1 part of cassia seed, 2 parts of lotus leaf, 2 parts of Radix Liriopes, 1.2 parts of the membrane of a chicken's gizzard, 2 parts of spina date seed, 1.4 parts of leaves of Hawthorn, crow 1.5 parts of plum, 0.5 part of saline cistanche.
3. blood pressure lowering composition according to claim 1 or 2, it is characterised in that further include honey.
4. a kind of preparation method of blood pressure lowering composition according to claim 3, it is characterised in that comprise the following steps：（1） Each raw material is weighed according to above-mentioned formula, it is spare；（2）By in the ginkgo leaf got ready, bluish dogbane, cassia seed, lotus leaf, Radix Liriopes, chicken Gold, spina date seed, leaves of Hawthorn, dark plum and saline cistanche after drying, grinding, are mixed to get medicinal powder respectively；（3）Honey is boiled, first Boiling is endured with high heat, then boils 10-20min with slow boiling；（4）The honey boiled is poured into the medicinal powder in container with spoon, together When stirred with chopsticks in medicinal powder, after being finished down honey, with the both hands after disinfection by medicinal powder and honey and for one；（5）Rubbing and Ball, packaging.
5. the preparation method of blood pressure lowering composition according to claim 4, it is characterised in that the weight ratio of medicinal powder and honey is 1:（1-1.5）.
6. the preparation method of blood pressure lowering composition according to claim 4, it is characterised in that and ball specification is 10g/.
CN201810012363.5A 2018-01-05 2018-01-05 A kind of blood pressure lowering composition and preparation method thereof Pending CN108014250A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4788798A (en) * 1986-03-24 1988-12-06 Ferro Corporation Adhesive system for maintaining flexible workpiece to a rigid substrate
CN103918821A (en) * 2014-04-08 2014-07-16 梁艳红 Health blood-pressure-reducing tea
CN105168437A (en) * 2015-11-08 2015-12-23 长沙佰顺生物科技有限公司 Pharmaceutical composition for treating coronary heart diseases and angina pectoris

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4788798A (en) * 1986-03-24 1988-12-06 Ferro Corporation Adhesive system for maintaining flexible workpiece to a rigid substrate
CN103918821A (en) * 2014-04-08 2014-07-16 梁艳红 Health blood-pressure-reducing tea
CN105168437A (en) * 2015-11-08 2015-12-23 长沙佰顺生物科技有限公司 Pharmaceutical composition for treating coronary heart diseases and angina pectoris

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Application publication date: 20180511