CN108008139A - A kind of intelligent automatic detection scheme of excreta and its implementation - Google Patents
A kind of intelligent automatic detection scheme of excreta and its implementation Download PDFInfo
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- CN108008139A CN108008139A CN201711087602.5A CN201711087602A CN108008139A CN 108008139 A CN108008139 A CN 108008139A CN 201711087602 A CN201711087602 A CN 201711087602A CN 108008139 A CN108008139 A CN 108008139A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00346—Heating or cooling arrangements
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Abstract
A kind of intelligent automatic detection scheme of excreta and its implementation, precisely obtain excreta special component data.Test strip project block sets identification code, enzyme process detection project determines detection terminal time according to environment temperature, chemical method detection project changes correction systematic error according to pH environment, according to excreta standing time, environment temperature, pollution condition, correct testing result, project block can locally heat, refrigeration, reagent is absorbed in addition, different detection projects set detection terminal at times, detection project abnormal results alarms and provides solution, and personalized setting detection program, realize that different type detection project coexists in same test strips, efficiently, accurately once complete excreta entry Indexs measure.
Description
Technical field
The present invention is the scheme on excreta in-vitro diagnosis, particularly relates to a kind of intelligent automatic detection scheme of excreta
And its implementation.
Background technology
The body discharges such as urine, excrement, leukorrhea, sperm, saliva, sputum, tear, ascites, cerebrospinal fluid, amniotic fluid, milk, sweat
Thing includes body important information, and excreta composition detection has become important clinical inspection item.
All-in-One ELISA test strip excreta Multiple components are used widely.Clinical excrement detection method includes enzyme
The technologies such as method, chemical method, immunization, biochip method.Although All-in-One ELISA test strip substantially meets hospital, high-volume is drained
The needs of thing pattern detection, but detection method still suffers from many deficiencies.
(1) different detection projects, enzyme used and substrate are different, its optimum detection terminal time must be inconsistent.It is and normal
Rule scheme, during a variety of item detections, is synchronously scanned detection, causes error；In addition, zymetology reaction is very quick to environment temperature
Sense, conventional detection cannot change detection terminal time with temperature, cause error or error result.
(2) chemical method detection project is had a great influence by pH environment, and conventional method cannot change and change with environment pH, will lead
Testing result is caused error occur.
(3) biochip method needs to heat, freeze, add or absorb reagent function, and examination cannot be accurately positioned in conventional method
The region intervened is needed on paper slip.
(4) faecal samples standing time, ambient temperature and humidity, pollution cause component to change, and conventional method cannot correct
The resultant error caused by standing time difference.
(5) conventional detection is previously set for the detection program of different detection projects, it is impossible to the intelligence with detection environmental change
Energyization, personalized adjustment detection program, and personalized algorithm is accordingly provided.
More than in view of, enzyme process detection determines detection terminal time according to environment temperature sequencing, and chemical method detection is according to pH
Environment changes correction systematic error, according to excreta standing time, ambient temperature and humidity, pollution condition, corrects testing result, detection
Project sets detection terminal, personalization setting detection program and algorithm at times, realizes that different type detection project coexists in together
One test strips, efficiently, accurately once complete excreta entry Indexs measure.
The content of the invention
It is an object of the present invention to provide a kind of intelligent automatic detection method of excreta, obtains excreta special component data.
According to environment temperature, pH, excreta standing time, pollution condition, testing result, individualized intelligentization setting detection journey are corrected
Sequence, realizes that different type detection project coexists in same test strips, efficiently, accurately once completes the inspection of excreta entry index
Survey.
To achieve the above object, solution of the invention is,
Excreta component and reagent reacting in test strip, detection device sequencing detection test strips color reaction, into
And the data message of excreta special component detection project is obtained, information issues user computer end, high in the clouds, intelligence by processing
Terminal.
The excreta include urine, excrement, leukorrhea, sperm, saliva, sputum, tear, ascites, cerebrospinal fluid, amniotic fluid, milk,
Sweat.
The test strip includes substrate and detection project block；The test strip sets identification code；The knowledge
Other code includes test strips type identification code and detection project block identification code；The different excretion species of the test strips type adaptation
Not；The detection project block identification code guides corresponding detection program.
The detection device includes take pictures video recording system, identifying system, physics and chemistry operating system, scanning analysis system；It is described
Video recording system of taking pictures is used to monitor ELISA test strip process, obtains excreta visible component data；The visible component includes row
Let out thing residue, cell or cell fragment, microorganism；The identifying system includes the identification of test strips identification code and excreta to be formed
Divided data identification, count, analysis；The physics and chemistry operating system includes realizing detection project block local heating, system according to program
Cold, reagent addition is absorbed；The scanning analysis system corresponds to the color reaction of detection project according to program scanning test strips, warp
Algorithm, obtains excreta compositional data；Described program includes instruction input, central data processing, data output；Described instruction is defeated
Enter and voluntarily change instruction according to detection environmental change including being manually entered instruction and detection device；Described program further includes personalization
Set detection program, abnormal results to alarm and solution is provided.
The detection project includes enzyme process detection project, chemical method detection project, immunization detection project, biochip method
Detection project.
The enzyme process detection project determines detection terminal time according to environment temperature；The detection terminal time refers to scanning and sets
The standby optimum time point for performing Scanning Detction；The optimum time point is actually examined by different detection projects under different physicochemical environments
Result optimizing is surveyed to obtain；The environment temperature exceeds zymetology range of reaction temperature, and corresponding detection project locally adds in test strips
Heat heating or refrigeration cool-down, keep environment temperature in preset range.
The chemical method detection project changes correction systematic error according to pH environment；The pH environment, which changes correction system, to be missed
Difference is obtained by detected value contrast in detected value under actual pH environment and pH buffering ranges；The pH environment exceedes buffer system model
Enclose, corresponding detection project locally adds acid or alkaline reagent in test strips, keeps pH environment in the buffer system model of setting
In enclosing；The biochip method detection project block locally possesses heating, refrigeration, addition or absorbs reagent function.
The detection project also includes the faecal samples resting period, and according to excreta standing time, ambient temperature and humidity,
Pollution condition, prediction component change, and correct detection project result.
The data message includes detection project result, interpretation of result, health evaluating, disease assistance medical diagnosis on disease.
The abnormal results alarm includes item detection result beyond given threshold scope, the failure of test strips reagent, excretion
Thing sample place too long, equipment operation it is abnormal；The solution include testing result error correction, self-changeable test strips,
Prompting leaves and takes faecal samples, voluntarily restarts equipment, reminds operator's manual intervention again.
The personalized setting detection program includes different excreta type sets, detection project control group sets, is specific
Intervening measure setting, measurement terminal time setting in detection project detection process；The intervening measure include human intervention and according to
Change intelligent adjustment according to physicochemical environment；The control group includes background blank control, reagent blank control, standard sample pair
According to.
The implementation method of the intelligent automatic detection scheme of excreta, implementation step include：Faecal samples pretreatment, examination
Paper slip infiltration sample, instrument and equipment program are set, test strips are sent into detection device, scanning recognition, data processing, testing result school
Just, data analysis, data transfer, be sent to user terminal, assist medical diagnosis on disease.
Brief description of the drawings
Fig. 1, test strips identification code are set
Fig. 2, enzyme process detection project detection terminal time adjustment flow chart
Fig. 3, chemical method detection project pH environmental correction flow charts
The intelligent automatic overhaul flow chart of Fig. 4, excreta
Embodiment
Technology contents, institute's reached purpose and effect for the detailed present invention, will enumerate embodiment and coordinate specification below
Attached drawing is described in detail.
A kind of intelligent automatic detection scheme of excreta, excreta component are set with reagent reacting in test strip, detection
Standby sequencing detection test strips color reaction, and then the data message of excreta special component detection project is obtained, information is passed through
Processing, issues user computer end, high in the clouds, intelligent terminal.
The excreta include urine, excrement, leukorrhea, sperm, saliva, sputum, tear, ascites, cerebrospinal fluid, amniotic fluid, milk,
Sweat；The excreta includes visible component and aeriform part；The excreta comes from the mankind or other animals.
As shown in Figure 1, test strip includes substrate 1 and detection project reagent block 2；The test strips substrate 1 and detection
Project reagent block 2 is respectively provided with identification code 3, identifies test strips type 31 and detection project subclass 32 respectively, wherein, type identification
The mark of code 31 marks local in each individual event detection project block 2 of test strips in test strips side, project subclass identification code 32；
The test strips type identification code 31 is adapted to different excreta classifications；The instruction of detection project subclass identification code 32 detection
Equipment uses corresponding detection program；The identification code can be one-dimensional, two-dimentional or three-D pattern；The identification code 3 uses state
The border universal standard, is identified by the detection device of general international standard.
The detection device includes take pictures video recording system, identifying system, physics and chemistry operating system, scanning analysis system；It is described
Video recording system of taking pictures is used to monitor ELISA test strip process, obtains excreta visible component data；The visible component includes row
Let out thing residue, cell or cell fragment, microorganism；The identifying system includes the identification of test strips identification code and excreta to be formed
Divide identification, count, analysis；The physics and chemistry operating system includes realizing detection project block local heating, refrigeration, examination according to program
Agent is added or absorbed；The scanning analysis system corresponds to the color reaction of detection project according to program scanning test strips, through algorithm,
Obtain excreta compositional data.
Described program includes instruction input, central data processing, data output；Described instruction input includes being manually entered finger
Order and detection device voluntarily change instruction according to detection environmental change；The central data processing includes command reception, equipment inspection
Survey environmental data collecting and processing, test strips and faecal samples.
The detection project includes enzyme process detection project, chemical method detection project, immunization detection project, biochip method
Detection project.
As shown in Fig. 2, the enzyme process detection project determines detection terminal time according to environment temperature；The environment temperature surpasses
Go out zymetology range of reaction temperature, corresponding detection project local heating heating or refrigeration cool-down, keep environment temperature in test strips
In preset range；The environment temperature meets zymetology range of reaction temperature, according under actual temperature, detection device using pair
The detection terminal time answered；The corresponding detection terminal time is by under different temperatures, actual observation enzyme-to-substrate response curve,
Obtain the optimum detection time；The different temperatures refers to the environment temperature at interval of 1 DEG C in zymetology range of reaction temperature.
As shown in figure 3, the chemical method detection project changes correction systematic error according to pH environment；The pH environment exceedes
Buffer system scope, locally addition is acid or alkaline reagent, acid reagent usually select for corresponding detection project block in test strips
Use NaHCO3, alkaline reagent usually selects Na2CO3, pH environment is kept in the range of the buffer system of setting；The pH environment changes
Become correction systematic error to be obtained by detected value contrast under detected value under actual pH environment and standard pH environment, when secondary testing result passes through
After error correction, final result is exported.
The biochip method detection project block locally possesses heating, refrigeration, addition or absorbs reagent function, is detecting
Completed in equipment.
The detection project also includes the faecal samples resting period, and according to excreta standing time, ambient temperature and humidity,
Pollution condition, prediction component change, and correct detection project result；The resting period by user annotation excreta acquisition time
Determine, or special component changes of contents obtains in detection faecal samples, the time that this special component leaves body with sample increases
Add and rule change.
Described program further includes personal settings detection program, detection project abnormal results is alarmed and provides solution；
The personalized setting is included by preset program setting and intelligent program setting；The preset program setting refers to different detections
Mesh sets different detection terminal times；The intelligent program refers to environment temperature, the pH that foundation monitors in real time, according to special algorithm
Voluntarily determine the detection time terminal of sub-project；The detection terminal time refers to the Best Times that scanning device performs Scanning Detction
Point；By different detection projects, the actually detected result optimizing under different physicochemical environments obtains the optimum time point.
The personalized setting detection program further includes excreta type set, the setting of detection project control group, specific inspection
Intervening measure sets, measures terminal time setting during surveying item detection；The intervening measure includes human intervention and foundation
Physicochemical environment changes intelligent adjustment, and human intervention is adjusted in real time by operator according to field condition, and intelligent adjustment is complete
Got wisdom by detection device repetition learning human intervention data；The control group includes background blank control, reagent blank pair
According to the control of, standard sample, background blank control is used to cut down interference of faecal samples itself pigment to chromogenic reaction, and reagent is empty
For cutting down interference of reagent itself pigment to chromogenic reaction, standard sample compares to be used to control detects quality simultaneously when secondary for white control
Quantitatively calculate excreta component；The measurement terminal time setting includes artificial preset and according to physicochemical environment change intelligence
Energyization is set, wherein, intelligence setting includes a large amount of practical datas of detection device reading learning and scientific data, with reference to when time inspection
The physicochemical environment of survey, sets optimal measurement terminal time.
The abnormal results alarm includes item detection result beyond given threshold scope, the failure of test strips reagent, excretion
Thing sample place too long, equipment operation it is abnormal；The solution include testing result error correction, self-changeable test strips,
Prompting user leaves and takes faecal samples, voluntarily restarts equipment, reminds operator's manual intervention again.
The data message includes detection project result, interpretation of result, health evaluating, disease assistance diagnosis.
As shown in figure 4, a kind of intelligent automatic detection scheme of excreta realizes step, specifically include：Faecal samples
Collection, faecal samples pretreatment, test strips type is chosen, test strips infiltrate sample, instrument and equipment program is set, test strips are sent
Enter detection device, scanning recognition, data processing, testing result correction, data analysis, data transfer, be sent to user terminal, assessment
Health status, assist medical diagnosis on disease, instruct to see a doctor.
The above, is only the embodiment of the present invention, is not intended to limit the scope of the present invention, therefore every
Any subtle modifications, equivalent variations and modifications that technical spirit according to the present invention makees above example, still fall within this
In the range of inventive technique scheme.
Claims (8)
- A kind of 1. intelligent automatic detection scheme of excreta, it is characterised in that：Excreta component and reagent in test strip are anti- Should, detection device sequencing detection test strips color reaction, and then the data message of excreta special component detection project is obtained, Information issues user terminal by processing.The excreta includes urine, excrement, leukorrhea, sperm, saliva, sputum, tear, ascites, cerebrospinal fluid, amniotic fluid, milk, sweat Liquid；The test strip includes substrate and detection project block；The test strip sets identification code；The detection device includes take pictures video recording system, identifying system, physics and chemistry operating system, scanning analysis system；It is described to take pictures Video recording system is used to monitor ELISA test strip process, obtains excreta visible component data；The visible component includes excreta Residue, cell or cell fragment, microorganism；The identifying system includes the identification of test strips identification code and excreta visible component is known Not, count, analysis；The physics and chemistry operating system includes realizing detection project block Local delivery according to program；The scanning point Analysis system corresponds to the color reaction of detection project according to program scanning test strips, through algorithm, obtains excreta compositional data；Described program includes instruction input, central data processing, data output；Described instruction input include be manually entered instruction and Detection device voluntarily changes instruction according to detection environmental change；The detection project includes enzyme process detection project, chemical method detection project, immunization detection project, the detection of biochip method Project；The enzyme process detection project determines detection terminal time according to environment temperature；The environment temperature is beyond zymetology reaction temperature Scope is spent, corresponding detection project block local heating heating or refrigeration cool-down, keep environment temperature presetting in test strips In the range of；The chemical method detection project changes correction systematic error according to pH environment；The pH environment overruns, test strips Upper corresponding detection project block locally adds acid or alkaline reagent, keeps pH environment in setting range；The biology core Piece method detection project block locally possesses heating, refrigeration, addition or absorbs reagent function；The detection project also includes the faecal samples resting period, and according to excreta standing time, environment temperature, pollution feelings Condition, prediction component change, correction error；Described program further includes personal settings detection program, abnormal results is alarmed and provides solution；The data message includes detection project result, interpretation of result, health evaluating, disease assistance diagnosis.
- 2. the intelligent automatic detection scheme of excreta as claimed in claim 1, it is characterised in that：The identification code includes test paper Bar type identification code and detection project block identification code；The different excreta classification of the test strips type adaptation；The detection Project block identification code is used to guide the corresponding detection program of detection device.
- 3. the intelligent automatic detection scheme of excreta as claimed in claim 1, it is characterised in that：The detection terminal time refers to Scanning device performs the optimum time point of Scanning Detction；The optimum time point is by different detection projects under different physicochemical environments Actually detected result optimizing obtains.
- 4. the intelligent automatic detection scheme of excreta as claimed in claim 1, it is characterised in that：The pH environment changes correction Systematic error is obtained by detected value contrast in the range of detected value under actual pH environment and standard pH buffer.
- 5. the intelligent automatic detection scheme of excreta as claimed in claim 1, it is characterised in that：The personalized setting includes By preset program setting and intelligent program setting；The preset program setting refers to different detection projects and sets different detection terminals Time；The intelligent program setting refers to environment temperature, the pH that foundation monitors in real time, and sub-project is voluntarily determined according to special algorithm Detection time terminal.
- 6. the intelligent automatic detection scheme of excreta as claimed in claim 1, it is characterised in that：The abnormal results alarm bag Include item detection result beyond given threshold scope, test strips reagent failure, faecal samples place too long, equipment operation it is different Often；The solution include testing result error correction, self-changeable test strips, prompting leave and take again faecal samples, from Row restarting equipment, remind operator's manual intervention.
- 7. the intelligent automatic detection scheme of excreta as claimed in claim 1, it is characterised in that：The personalized setting detection Program includes intervening measure during different excreta type sets, the setting of detection project control group, particular detection item detection Setting, measurement terminal time setting；The intervening measure includes human intervention and changes intelligent adjustment according to physicochemical environment；Institute Stating control group includes background blank control, reagent blank control, standard sample control.
- A kind of 8. implementation method of the intelligent automatic detection scheme of excreta, it is characterised in that：Intelligent automatic detection scheme Realize that step includes：Faecal samples pretreatment, test strips infiltration sample, instrument and equipment program is set, test strips are sent into detection Equipment, scanning recognition, data processing, testing result correction, data analysis, data transfer, be sent to user terminal, assist disease examine It is disconnected.
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| CN112505027A (en) * | 2020-11-15 | 2021-03-16 | 厦门波耐模型设计有限责任公司 | Detection method, device and system of integrated detection test paper |
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Application publication date: 20180508 |