CN107998310A - A kind of Chinese medicine composition for treating cervicitis and preparation method thereof - Google Patents

A kind of Chinese medicine composition for treating cervicitis and preparation method thereof Download PDF

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CN107998310A
CN107998310A CN201711303653.7A CN201711303653A CN107998310A CN 107998310 A CN107998310 A CN 107998310A CN 201711303653 A CN201711303653 A CN 201711303653A CN 107998310 A CN107998310 A CN 107998310A
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孔令敏
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994—Coix (Job's tears)
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/413—Gall bladder; Bile
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • A—HUMAN NECESSITIES
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    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The invention discloses a kind of Chinese medicine composition for treating cervicitis and preparation method thereof, which is made using cow-bezoar, Sichuan troops, wild chrysanthemum, Chinese ephedra, Rhizoma Atractylodis Macrocephalae, Semen Cuscutae, felwort, honeysuckle, Cortex Phellodendri, the bark of eucommia 1, reticulate millettia, peppermint, Fructus Malvae Vertillatae, Sculellaria barbata, raw pearl barley, Radix Salviae Miltiorrhizae, the root of bidentate achyranthes, Ramulus Taxilli, field pennycress of primary raw material.Chinese medicine composition of the present invention has extensive pharmacology and a physiological activity, Chinese medicine composition reasonable recipe, have heat-clearing and damp-drying drug, dampness removing stop-band, remove necrosis and promote granulation, antibacterial anti-inflammatory the effect of, and short treating period, healing time is fast, evident in efficacy, is worth clinical application；In addition, the present invention is Chinese medicine preparation, absorption is fast, drug effect is rapid, active constituent content is high, dose is few, safe and free of toxic and side effects.

Description

A kind of Chinese medicine composition for treating cervicitis and preparation method thereof
Technical field
The present invention relates to technical field of traditional Chinese medicines, more particularly to a kind of Chinese medicine composition for treating cervicitis and its preparation side Method.
Background technology
Cervicitis is the commonly encountered disease of childbearing age, and clinic is divided into acute and chronic two kinds, using chronic cervicitis to be common, Its pathological manifestations is mainly cervical canal mucous membrane and congestion and edema, inflammatory cell infiltration and connective tissue proliferation, disease are organized in its underpart Feelings such as further development can cause cervical erosion, according to waste rotten face size be often classified as it is light, in, three kinds of severe, all erosion areas It is slight less than the uterine neck gross area, it is moderate to account for 1/3-1/2 person, is severe more than 1/2 gross area person.It is rotten to treat uterine neck Rotten externally applied drug has Baofukang suppository etc., and Baofukang suppository is filled in uterine neck, effective in cure to cervicitis, but moderate and severe cervical is cured Rate is very low.
Clinical manifestation is to increase under band, and the milky white matter of color is sticky or in yellowish purulence sample, and underbelly pendant pain, vagina is fallen or yellowish purulence Sample, while tired with soreness of waist god, underbelly pendant pain, pruritus vulvae, cloudy pain etc., middle severe cervical scorching can be directed at infertile, can also be directed at uterine neck Cancer.
Treatment cervicitis has many methods at present, can be divided into physical therapy and medicinal treatment, physical therapy is irradiated with laser Exemplified by use carbon dioxide laser defocus irradiation, 70 watts of power, irradiation 10-15 minutes every time, 10 times are as a treatment course, need to generally control Treat two months.Although this treatment method has definite curative effect, but treatment time is grown, costly.Drug therapy has oral medicine and outer Medication.Oral medicine treatment time is grown, and body is adversely affected.
The content of the invention
It is an object of the present invention to provide a kind of effective Chinese medicine composition for being used to treat cervicitis and preparation method thereof.
In order to solve the above technical problems, the present invention provides following technical solution：
A kind of Chinese medicine composition for treating cervicitis, the raw material composition of the medicine are：Cow-bezoar 15-25 parts by weight, Sichuan troops 10-15 weights Measure part, wild chrysanthemum 10-15 parts by weight, Chinese ephedra 5-10 parts by weight, Rhizoma Atractylodis Macrocephalae 8-20 parts by weight, Semen Cuscutae 10-20 parts by weight, felwort 10-15 parts by weight, honeysuckle 10-15 parts by weight, Cortex Phellodendri 10-15 parts by weight, bark of eucommia 10-20 parts by weight, reticulate millettia 10-20 weight Part, peppermint 10-15 parts by weight, Fructus Malvae Vertillatae 10-15 parts by weight, Sculellaria barbata 10-15 parts by weight, raw pearl barley 10-20 parts by weight, Radix Salviae Miltiorrhizae 10-15 parts by weight, root of bidentate achyranthes 10-15 parts by weight, Ramulus Taxilli 10-15 parts by weight, field pennycress 10-15 parts by weight.
Further optimization, the raw material composition of the medicine are：The raw material of the medicine forms：20 parts by weight of cow-bezoar, Sichuan troops 12 Parts by weight, 12 parts by weight of wild chrysanthemum, 8 parts by weight of Chinese ephedra, 15 parts by weight of Rhizoma Atractylodis Macrocephalae, 15 parts by weight of Semen Cuscutae, 12 parts by weight of felwort, 12 parts by weight of honeysuckle, 12 parts by weight of Cortex Phellodendri, 15 parts by weight of the bark of eucommia, 15 parts by weight of reticulate millettia, 12 parts by weight of peppermint, Fructus Malvae Vertillatae 12 Parts by weight, 12 parts by weight of Sculellaria barbata, 15 parts by weight of raw pearl barley, 12 parts by weight of Radix Salviae Miltiorrhizae, 12 parts by weight of the root of bidentate achyranthes, 12 weight of Ramulus Taxilli Part, 12 parts by weight of field pennycress.
The present invention also provides the preparation method of said medicine, include the following steps：
After bulk pharmaceutical chemicals each component is mixed in mass fraction ratio, ultramicro grinding is carried out, 1000 mesh sieves is crossed, obtains Ultramicro-powder, to Added in Ultramicro-powder and account for the ethanol solution that the mass concentration that 10 times of medicine gross mass is measured is 90%, 24h is placed in refrigeration, and filtering, obtains To filtrate, recycling ethanol obtains extracting solution, extracting solution is concentrated to dryness, and dry extract is obtained after vacuum drying；By dry extract plus routine Auxiliary material, is made capsule, pill, tablet, granule, liquid oral according to a conventional method.
Chinese medicine composition of the present invention has extensive pharmacology and physiological activity, specifically has the beneficial effect that：In the present invention Drug composition reasonable recipe, have heat-clearing and damp-drying drug, dampness removing stop-band, remove necrosis and promote granulation, antibacterial anti-inflammatory the effect of, and short treating period, healing Time is fast, evident in efficacy, is worth clinical application；In addition, the present invention is Chinese medicine preparation, absorb fast, drug effect is rapid, effectively into Divide content height, dose few, safe and free of toxic and side effects.
Embodiment
Further supplement, but do not limit the invention in any way are done to the present invention with reference to specific embodiment.
Embodiment 1
The raw material and weight of medicine of the present invention be：
20 parts by weight of cow-bezoar, 12 parts by weight of Sichuan troops, 12 parts by weight of wild chrysanthemum, 8 parts by weight of Chinese ephedra, 15 parts by weight of Rhizoma Atractylodis Macrocephalae, Semen Cuscutae 15 parts by weight, 12 parts by weight of felwort, 12 parts by weight of honeysuckle, 12 parts by weight of Cortex Phellodendri, 15 parts by weight of the bark of eucommia, 15 weight of reticulate millettia Part, 12 parts by weight of peppermint, 12 parts by weight of Fructus Malvae Vertillatae, 12 parts by weight of Sculellaria barbata, 15 parts by weight of raw pearl barley, 12 parts by weight of Radix Salviae Miltiorrhizae, ox 12 parts by weight of knee, 12 parts by weight of Ramulus Taxilli, 12 parts by weight of field pennycress.
Preparation method is as follows：
After bulk pharmaceutical chemicals each component is mixed in mass fraction ratio, ultramicro grinding is carried out, 1000 mesh sieves is crossed, obtains Ultramicro-powder, to Added in Ultramicro-powder and account for the ethanol solution that the mass concentration that 10 times of medicine gross mass is measured is 90%, 24h is placed in refrigeration, and filtering, obtains To filtrate, recycling ethanol obtains extracting solution, extracting solution is concentrated to dryness, and dry extract is obtained after vacuum drying；By dry extract plus routine Auxiliary material, is made capsule, pill, tablet, granule, liquid oral according to a conventional method.
Usage and dosage：It is oral, take after meal；3 times a day, ten days as a treatment course, six to eight courses for the treatment of can cure, the state of an illness Severe patient increases the amount of discretion, and pregnant woman's disabling, sportsman uses with caution.
Embodiment 2
The raw material of medicine of the present invention forms and weight is：
20 parts by weight of cow-bezoar, 12 parts by weight of Sichuan troops, 12 parts by weight of wild chrysanthemum, 8 parts by weight of Chinese ephedra, 15 parts by weight of Rhizoma Atractylodis Macrocephalae, Semen Cuscutae 15 parts by weight, 12 parts by weight of felwort, 12 parts by weight of honeysuckle, 12 parts by weight of Cortex Phellodendri, 15 parts by weight of the bark of eucommia, 15 weight of reticulate millettia Part, 12 parts by weight of peppermint, 12 parts by weight of Fructus Malvae Vertillatae, 12 parts by weight of Sculellaria barbata, 15 parts by weight of raw pearl barley, 12 parts by weight of Radix Salviae Miltiorrhizae, ox 12 parts by weight of knee, 12 parts by weight of Ramulus Taxilli, 12 parts by weight of field pennycress.
The present embodiment Chinese medicine preparation preparation method processing step and usage and dosage are same as Example 1.
Embodiment 3
20 parts by weight of cow-bezoar, 12 parts by weight of Sichuan troops, 12 parts by weight of wild chrysanthemum, 8 parts by weight of Chinese ephedra, 15 parts by weight of Rhizoma Atractylodis Macrocephalae, Semen Cuscutae 15 parts by weight, 12 parts by weight of felwort, 12 parts by weight of honeysuckle, 12 parts by weight of Cortex Phellodendri, 15 parts by weight of the bark of eucommia, 15 weight of reticulate millettia Part, 12 parts by weight of peppermint, 12 parts by weight of Fructus Malvae Vertillatae, 12 parts by weight of Sculellaria barbata, 15 parts by weight of raw pearl barley, 12 parts by weight of Radix Salviae Miltiorrhizae, ox 12 parts by weight of knee, 12 parts by weight of Ramulus Taxilli, 12 parts by weight of field pennycress.
The present embodiment Chinese medicine preparation preparation method processing step and usage and dosage are same as Example 1.
Clinical test：
Subjects totally 120,32 to 68 years old ages；The course of disease 3 to 18 years, piece of the experimental drug thing prepared by the present embodiment 1 Agent, the equal reference of tcm diagnosis《Disease of tcm Standardization of diagnosis and curative effect》Formulate, the standard reference of doctor trained in Western medicine diagnosis《Gynecotokology》Formulate.
Treatment method：It is oral, take after meal；3 times a day, 4 tablets once, ten days as a treatment course,
Observe result：It is shown in Table 1.
1 Tablets of table treat the observation result of cervicitis
Clinical recovery It is effective Effectively It is invalid Cure rate/% Total effective rate/%
83 22 15 69.2 100
Moreover, it will be appreciated that although the present specification is described in terms of embodiments, not each embodiment only includes one A independent technical solution, this narrating mode of specification is only that those skilled in the art will should say for clarity Bright book is as an entirety, and the technical solutions in the various embodiments may also be suitably combined, and forming those skilled in the art can be with The other embodiment of understanding.

Claims (3)

  1. A kind of 1. Chinese medicine composition for treating cervicitis, it is characterised in that：The raw material of the medicine forms：Cow-bezoar 15-25 weight Part, Sichuan troops' 10-15 parts by weight, wild chrysanthemum 10-15 parts by weight, Chinese ephedra 5-10 parts by weight, Rhizoma Atractylodis Macrocephalae 8-20 parts by weight, Semen Cuscutae 10- 20 parts by weight, felwort 10-15 parts by weight, honeysuckle 10-15 parts by weight, Cortex Phellodendri 10-15 parts by weight, bark of eucommia 10-20 parts by weight, Reticulate millettia 10-20 parts by weight, peppermint 10-15 parts by weight, Fructus Malvae Vertillatae 10-15 parts by weight, Sculellaria barbata 10-15 parts by weight, raw pearl barley 10-20 parts by weight, Radix Salviae Miltiorrhizae 10-15 parts by weight, root of bidentate achyranthes 10-15 parts by weight, Ramulus Taxilli 10-15 parts by weight, field pennycress 10-15 weight Part.
  2. 2. the Chinese medicine composition for the treatment of cervicitis according to claim 1, it is characterised in that：The raw material composition of the medicine For：20 parts by weight of cow-bezoar, 12 parts by weight of Sichuan troops, 12 parts by weight of wild chrysanthemum, 8 parts by weight of Chinese ephedra, 15 parts by weight of Rhizoma Atractylodis Macrocephalae, Semen Cuscutae 15 Parts by weight, 12 parts by weight of felwort, 12 parts by weight of honeysuckle, 12 parts by weight of Cortex Phellodendri, 15 parts by weight of the bark of eucommia, 15 weight of reticulate millettia Part, 12 parts by weight of peppermint, 12 parts by weight of Fructus Malvae Vertillatae, 12 parts by weight of Sculellaria barbata, 15 parts by weight of raw pearl barley, 12 parts by weight of Radix Salviae Miltiorrhizae, ox 12 parts by weight of knee, 12 parts by weight of Ramulus Taxilli, 12 parts by weight of field pennycress.
  3. A kind of 3. preparation method for the Chinese medicine composition for treating cervicitis, it is characterised in that：Comprise the following steps：Bulk pharmaceutical chemicals are each After component is mixed in mass fraction ratio, ultramicro grinding is carried out, 1000 mesh sieves is crossed, obtains Ultramicro-powder, add and account for into Ultramicro-powder 24h is placed in the ethanol solution that the mass concentration of 10 times of amounts of medicine gross mass is 90%, refrigeration, and filtering, obtains filtrate, recycles ethanol Extracting solution is obtained, extracting solution is concentrated to dryness, dry extract is obtained after vacuum drying；By dry extract plus customary adjuvant, according to a conventional method Capsule, pill, tablet, granule, liquid oral is made.
CN201711303653.7A 2017-12-11 2017-12-11 A kind of Chinese medicine composition for treating cervicitis and preparation method thereof Pending CN107998310A (en)

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Citations (2)

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