CN107982150A - A kind of anti-inflammation hemostasia oral care lotion - Google Patents
A kind of anti-inflammation hemostasia oral care lotion Download PDFInfo
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- CN107982150A CN107982150A CN201711429963.3A CN201711429963A CN107982150A CN 107982150 A CN107982150 A CN 107982150A CN 201711429963 A CN201711429963 A CN 201711429963A CN 107982150 A CN107982150 A CN 107982150A
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- oral care
- care lotion
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Oral & Maxillofacial Surgery (AREA)
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- Birds (AREA)
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- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Abstract
A kind of anti-inflammation hemostasia oral care lotion, it includes following components in parts by weight：1.2~2.5 parts of sodium alginate；1.0~3.0 parts of sodium lauroyl sarcosine；28~40 parts of moisturizer；0.2~0.5 part of sweetener；0.3~0.7 part of thickener；30~50 parts of rubbing agent；10~25 parts of deionized water；7~10 parts of marigold；The rubbing agent is wolf's milk powder.The present invention uses wolf's milk powder not only effectively to drive away tooth stain as the rubbing agent of oral care lotion, but also is avoided that therefore friction causes the phenomenon of bleeding gums, and need not add new hemostatic compositions, so as to reduce the production cost of oral care lotion.
Description
Technical field
The present invention relates to a kind of daily necessities technical field, more particularly to a kind of anti-inflammation hemostasia oral care lotion.
Background technology
Periodontal disease is common mouth disease, its symptom mainly has bleeding gums, swelling, pain.There is statistics to show, tooth
The main reason for all diseases are more than 35 years old crowd's absence of tooth, it is seen that the seriousness of periodontal disease.But since patient is not easy to examine
Feel, most people is not aware that oneself is suffered from this disease.Think that people can just suffer from periodontal disease to old many human factor errors, it is actual
Upper 5 year old, children can suffer from gingivitis.
Periodontosis is not only to influence the health of tooth, can also systemic health.Periodontosis is to whole body health in recent years
Influence caused the concern of people.Bacterial component and bacterial product are easy to be diffused into by oral pocket ulcer surface nearby or remote
Every organ, cause or aggravate some general diseases, such as coronary heart disease, low birth weight infant, diabetes, the hair of pulmonary infection disease
Hair tonic exhibition, seriously endangers health.It is that can not meet that people improve oral health water to depend merely on stomatological hospital and drug therapy
Flat needs, with the use of the oral cavity nursing health products with prevention periodontal disease, periodontal disease is that progressively to be had
Imitate what is prevented and control.
In order to preferably prevent periodontal disease, many people's selections are added into rubbing agent in toothpaste, but are added into friction
After agent, people have found the easy bleeding of gum when carrying out oral care using the toothpaste with rubbing agent, so as to be easy to cause sense
Dye, and in order to stop blooding, also need to be added into hemostatic compositions in also toothpaste, must can so increase the production of oral care lotion
Cost.
The content of the invention
It is an object of the invention to overcome the shortcomings of that the above and defect propose a kind of anti-inflammation hemostasia oral care lotion.
For this purpose, the present invention uses following technical scheme：
A kind of anti-inflammation hemostasia oral care lotion, it includes following components in parts by weight：
1.2~2.5 parts of sodium alginate；
1.0~3.0 parts of sodium lauroyl sarcosine；
28~40 parts of moisturizer；
0.2~0.5 part of sweetener；
0.3~0.7 part of thickener；
15~30 parts of rubbing agent；
10~25 parts of deionized water；
7~10 parts of marigold；
The rubbing agent is wolf's milk powder.
Preferably, it further includes 0.02-0.06 portions of preservatives.
Preferably, the preservative is more than one or both of isothiazolinone, nipagin esters, potassium sorbate mixed
Compound.
Preferably, the moisturizer compounds for the one or more of which of propane diols, butanediol or glycine betaine.
Preferably, the sweetener is the one or two of saccharin sodium or xylitol.
Preferably, the thickener is sodium carboxymethylcellulose, hydroxyethyl cellulose, the one or more of carbomer answer
Match somebody with somebody.
Preferably, the size of wolf's milk powder is 500-1000 mesh.If the powder used crosses expense when conference causes to brush teeth
Power, causes the inconvenience brushed teeth；If too small, easily remained in the gap of tooth in friction process, friction is reduced, so as to drop
The ability that low tooth stain is driven away.And wolf's milk floury texture is not hard, injury of teeth will not be caused.
The present invention is used as rubbing agent by adding wolf's milk powder in oral care lotion, makes the oral care of acquisition
Lotion can quickly remove the dirt for being attached to dental surface, tooth jaundice or long decayed tooth be avoided, simultaneously because the effect of friction, tooth
The easy bleeding of gum, and humid euphorbia grass meal has effects that cooling blood and hemostasis in itself, therefore use in wolf's milk powder as rubbing agent
Oral care lotion not only effectively drives away tooth stain, but also can avoid therefore rub to cause the phenomenon of bleeding gums, and need not
New hemostatic compositions are added, so as to reduce the production cost of oral care lotion.
Embodiment
Technical scheme is further illustrated below by embodiment.
Embodiment 1
A kind of anti-inflammation hemostasia oral care lotion, it includes following components in parts by weight：
1.2 parts of sodium alginate；
1.0 parts of sodium lauroyl sarcosine；
28 parts of glycine betaine；
0.2 part of saccharin sodium；
0.3 part of sodium carboxymethylcellulose；
Wolf's milk powder：Additive amount is added by table 1；
0.02 part of nipagin esters；
10 parts of deionized water；
7 parts of marigold.
Table 1 is influence of the additive amount of rubbing agent to expeling tooth stain ability
It can be obtained by table 1, rubbing agent of the wolf's milk powder as toothpaste, the ability for driving away tooth stain enhances, and not
Pipe is that the expeling dirt ability for being directed to the tooth stain for being aged 15 days or 30 days can reach more than 91, and optimal expeling is dirty
It using the ability of 28 parts of wolf's milk powder as the expeling tooth stain of the toothpaste of rubbing agent is most strong that dirty effect, which is,.
In order to test the effect of the present embodiment 1-1 to embodiment 1-3 obtains the hemostasis aspect of oral care lotion, carry out small
The clinical hemostasis experiment of the clinical hemostasis experiment mice of mouse.
Clinical trial of stopping blooding uses blank lotion, black younger sister's toothpaste, lengsuanling toothpaste, embodiment 1-1 into embodiment 1-3
Oral care lotion is as examination thing sample.
Carried out using hemostasis observational technique is damaged to mouse liver local woanded surface.Take the kunming mice 108 of health, weight
18~22g, male and female dual-purpose.After anesthetized mice, liver is cut in left lobe of liver with operating scissors and be about 0.5cm, wide about 0.5cm, it is high about
0.5cm, after the blood for wiping ejection, immediately in situation portion spreading thing sample 0.5g to be tried, oppresses 1min, after 1min with 200g counterweights
Counterweight is removed, haemostatic effect is observed, untill not bleeding.Such as still bleeding, add to apply and pressurize after thing sample is tried, observed every 30s
Once, bleeding stopping period is recorded, is such as no more than 3min, being then denoted as to stop blooding；Such as fail to stop blooding more than 3min, be then denoted as and fail to stop
Blood, experimental result are shown in Table 2.
The clinical blood coagulation hemostasis experimental result of 2 mouse of table
| Try thing sample | Experiment number | Bleeding stopping period |
| Blank lotion | 18 | ＞ 3 |
| Black younger sister's toothpaste | 18 | 2.70±0.22 |
| Lengsuanling toothpaste | 18 | 2.58±0.18 |
| The oral care lotion of embodiment 1-1 | 18 | 2.32±0.15 |
| The oral care lotion of embodiment 1-2 | 18 | 2.18±0.13 |
| The oral care lotion of embodiment 1-3 | 18 | 2.10±0.12 |
As seen from table, the oral care lotion of embodiment 1-1 to embodiment 1-3 is to mouse liver local woanded surface bleeding due to trauma
There is obvious blood coagulation haemostatic effect.
Embodiment 2
A kind of anti-inflammation hemostasia oral care lotion, it includes following components in parts by weight：
2.5 parts of sodium alginate；
3.0 parts of sodium lauroyl sarcosine；
30 parts of butanediol；
0.3 part of saccharin sodium；
0.7 part of hydroxyethyl cellulose；
Wolf's milk powder：17 parts；
0.06 part of potassium sorbate；
20 parts of deionized water；
7.5 parts of marigold.
The oral care lotion of the present embodiment is 96/12 day for the expeling ability of the tooth stain of ageing 15 days；For
The expeling ability of the tooth stain of ageing 30 days is 91/16 day.
Embodiment 3
A kind of anti-inflammation hemostasia oral care lotion, it includes following components in parts by weight：
1.5 parts of sodium alginate；
2.0 parts of sodium lauroyl sarcosine；
32 parts of propane diols；
0.5 part of xylitol；
0.6 part of carbomer；
Wolf's milk powder：23.5 parts；
0.04 part of isothiazolinone；
12.5 parts of deionized water；
10 parts of marigold.
The oral care lotion of the present embodiment is 97/10 day for the expeling ability of the tooth stain of ageing 15 days；For
The expeling ability of the tooth stain of ageing 30 days is 92/13 day.
Embodiment 4
A kind of anti-inflammation hemostasia oral care lotion, it includes following components in parts by weight：
1.75 parts of sodium alginate；
1.5 parts of sodium lauroyl sarcosine；
35 parts of glycine betaine；
0.3 part of saccharin sodium；
0.2 part of sodium carboxymethylcellulose, 0.2 part of hydroxyethyl cellulose, 0.3 part of carbomer；
19.5 parts of wolf's milk powder；
Nipagin esters 0.25,0.15 part of potassium sorbate；
22 parts of deionized water；
9 parts of marigold.
The oral care lotion of the present embodiment is 96/11 day for the expeling ability of the tooth stain of ageing 15 days；For
The expeling ability of the tooth stain of ageing 30 days is 92/15 day.
Embodiment 5
A kind of anti-inflammation hemostasia oral care lotion, it includes following components in parts by weight：
2 parts of sodium alginate；
2.5 parts of sodium lauroyl sarcosine；
30 parts of butanediol；
0.4 part of xylitol；
0.4 part of sodium carboxymethylcellulose, 0.2 part of hydroxyethyl cellulose；
27 parts of wolf's milk powder,
0.02 part of isothiazolinone, 0.03 part of nipagin esters；
14 parts of deionized water；
9.5 parts of marigold.
The oral care lotion of the present embodiment is 98/11 day for the expeling ability of the tooth stain of ageing 15 days；For
The expeling ability of the tooth stain of ageing 30 days is 93/13 day.
Embodiment 6
A kind of anti-inflammation hemostasia oral care lotion, it includes following components in parts by weight：
1.8 parts of sodium alginate；
2 parts of sodium lauroyl sarcosine；
38 parts of propane diols；
0.3 part of xylitol, 0.2 part of saccharin sodium；
0.1 part of sodium carboxymethylcellulose, 0.3 part of carbomer；
Wolf's milk powder：20.5 parts；
0.05 part of isothiazolinone；
17.5 parts of deionized water；
8.5 parts of marigold.
The oral care lotion of the present embodiment is 97/12 day for the expeling ability of the tooth stain of ageing 15 days；For
The expeling ability of the tooth stain of ageing 30 days is 92/14 day.
Embodiment 7
A kind of anti-inflammation hemostasia oral care lotion, it includes following components in parts by weight：
2.2 parts of sodium alginate；
2.7 parts of sodium lauroyl sarcosine；
10 parts of propane diols, 21 parts of glycine betaine；
0.3 part of saccharin sodium；
0.25 part of hydroxyethyl cellulose, 0.35 part of carbomer；
26.5 parts of wolf's milk powder；
0.01 part of isothiazolinone, 0.01 part of potassium sorbate；
14.5 parts of deionized water；
8.5 parts of marigold.
The oral care lotion of the present embodiment is 98/12 day for the expeling ability of the tooth stain of ageing 15 days；For
The expeling ability of the tooth stain of ageing 30 days is 92/13 day.
Embodiment 8
A kind of anti-inflammation hemostasia oral care lotion, it includes following components in parts by weight：
1.4 parts of sodium alginate；
2.5 parts of sodium lauroyl sarcosine；
24 parts of butanediol, 10 parts of glycine betaine；
0.3 part of xylitol, 0.1 part of saccharin sodium；
0.55 part of hydroxyethyl cellulose；
Wolf's milk powder：24 parts；
0.01 part of isothiazolinone, 0.02 part of nipagin esters；
9.5 parts of marigold.
The oral care lotion of the present embodiment is 98/12 day for the expeling ability of the tooth stain of ageing 15 days；For
The expeling ability of the tooth stain of ageing 30 days is 93/15 day.
Embodiment 9
A kind of anti-inflammation hemostasia oral care lotion, it includes following components in parts by weight：
2.4 parts of sodium alginate；
1.0 parts of sodium lauroyl sarcosine；
28 parts of propane diols, butanediol or glycine betaine；
0.25 part of xylitol；
0.35 part of sodium carboxymethylcellulose；
18.5 parts of wolf's milk powder；
0.02 part of isothiazolinone, 0.01 part of nipagin esters, 0.03 part of potassium sorbate；
15 parts of deionized water；
7 parts of marigold.
The oral care lotion of the present embodiment is 96/10 day for the expeling ability of the tooth stain of ageing 15 days；For
The expeling ability of the tooth stain of ageing 30 days is 91/16 day.
Embodiment 10
A kind of anti-inflammation hemostasia oral care lotion, it includes following components in parts by weight：
1.9 parts of sodium alginate；
1.8 parts of sodium lauroyl sarcosine；
14 parts of propane diols, 23 parts of butanediol；
0.2 part of xylitol, 0.25 part of saccharin sodium；
0.5 part of carbomer；
Wolf's milk powder：29 parts；
0.01 part of potassium sorbate, 0.02 part of isothiazolinone；
25 parts of deionized water；
10 parts of marigold.
The oral care lotion of the present embodiment is 97/10 day for the expeling ability of the tooth stain of ageing 15 days；For
The expeling ability of the tooth stain of ageing 30 days is 93/12 day.
Above in association with the specific embodiment technical principle that the invention has been described.These descriptions are intended merely to explain the present invention's
Principle, and limiting the scope of the invention cannot be construed in any way.Based on explanation herein, the technology of this area
Personnel would not require any inventive effort the other embodiments that can associate the present invention, these modes are fallen within
Within protection scope of the present invention.
Claims (7)
1. a kind of anti-inflammation hemostasia oral care lotion, it is characterised in that it includes following components in parts by weight：
1.2~2.5 parts of sodium alginate；
1.0~3.0 parts of sodium lauroyl sarcosine；
28~40 parts of moisturizer；
0.2~0.5 part of sweetener；
0.3~0.7 part of thickener；
30~50 parts of rubbing agent；
10~25 parts of deionized water；
7~10 parts of marigold；
The rubbing agent is wolf's milk powder.
A kind of 2. anti-inflammation hemostasia oral care lotion according to claim 1, it is characterised in that：It further includes 0.02-
0.06 portion of preservative.
A kind of 3. anti-inflammation hemostasia oral care lotion according to claim 2, it is characterised in that：The preservative is different thiophene
Mixture more than one or both of oxazoline ketone, nipagin esters, potassium sorbate.
A kind of 4. anti-inflammation hemostasia oral care lotion according to claim 1, it is characterised in that：The moisturizer is the third two
The one or more of which compounding of alcohol, butanediol or glycine betaine.
A kind of 5. anti-inflammation hemostasia oral care lotion according to claim 1, it is characterised in that：The sweetener is saccharin
The one or two of sodium or xylitol.
A kind of 6. anti-inflammation hemostasia oral care lotion according to claim 1, it is characterised in that：The thickener is carboxylic first
Base sodium cellulosate, hydroxyethyl cellulose, one or more compoundings of carbomer.
A kind of 7. anti-inflammation hemostasia oral care lotion according to claim 1, it is characterised in that：The wolf's milk powder
Size is 500-1000 mesh.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711429963.3A CN107982150A (en) | 2017-12-26 | 2017-12-26 | A kind of anti-inflammation hemostasia oral care lotion |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711429963.3A CN107982150A (en) | 2017-12-26 | 2017-12-26 | A kind of anti-inflammation hemostasia oral care lotion |
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| CN107982150A true CN107982150A (en) | 2018-05-04 |
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| CN201711429963.3A Withdrawn CN107982150A (en) | 2017-12-26 | 2017-12-26 | A kind of anti-inflammation hemostasia oral care lotion |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104248571A (en) * | 2014-09-19 | 2014-12-31 | 云南七丹药业股份有限公司 | Purely natural plant-containing abradant toothpaste and preparation method thereof |
-
2017
- 2017-12-26 CN CN201711429963.3A patent/CN107982150A/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104248571A (en) * | 2014-09-19 | 2014-12-31 | 云南七丹药业股份有限公司 | Purely natural plant-containing abradant toothpaste and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 老中医养生堂: "《本草纲目中药草使用图鉴》", 30 April 2016, 福建科学技术出版社 * |
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Application publication date: 20180504 |