CN107970401A - 一种治疗便秘的药物及其制作方法 - Google Patents

一种治疗便秘的药物及其制作方法 Download PDF

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CN107970401A
CN107970401A CN201610918835.4A CN201610918835A CN107970401A CN 107970401 A CN107970401 A CN 107970401A CN 201610918835 A CN201610918835 A CN 201610918835A CN 107970401 A CN107970401 A CN 107970401A
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constipation
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陈修仕
陈才献
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GUIZHOU RUNSHENG PHARMACEUTICAL Co Ltd
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Abstract

本发明公开了一种治疗便秘的药物及其制备方法，所述药物主要由黄连、黄柏、苍术、积雪草、独角莲、两头尖、对叶百部、枸杞子、甘草和仙人草制作而成。处方中各原料具有很好的协同作用，制成的药物可用于治疗便秘；疗效显著，治疗周期短，安全无副作用。

Description

一种治疗便秘的药物及其制作方法
技术领域
本发明涉及一种治疗便秘的药物及其制作方法，属于药品技术的领域。
背景技术
便秘(constipation)是指排便频率减少，一周内大便次数少于2～3次，或者2～3天才大便1次，粪便量少且干结时称为便秘。但有少数人平素一贯是2～3天才大便1次，且大便性状正常，此种情况不应认为是便秘；对同一人而言，如大便由每天1次或每2天1次变为2天以上或更长时间始大便1次时，应视为便秘。对便秘患者必须给予足够的重视。
针对上述疾病，虽然目前用于治疗便秘的药物有很多，但是大多数药物只是针对药效缓慢，治疗周期长。
发明内容
本发明的目的在于，提供一种治疗便秘的药物及其制作方法。所述药可用于治疗便秘；疗效显著，治疗周期短，安全无副作用。
为解决上述技术问题，本发明采用以下技术方案实现：一种治疗便秘的药物，按重量份计算，主要由黄连10-30份、黄柏1-20份、苍术10-30份、积雪草20-40份、独角莲10-30份、两头尖10-30份、对叶百部1-20份、枸杞子1-20份、甘草20-40份和仙人草20-40份制作而成。
前述的治疗便秘的药物，按重量份计算，主要由黄连15-25份、黄柏5-15份、苍术15-25份、积雪草25-35份、独角莲15-25份、两头尖15-25份、对叶百部1-20份、枸杞子5-15份、甘草25-35份和仙人草25-35份制作而成。
前述的治疗便秘的药物，按重量份计算，主要由黄连20份、黄柏10份、苍术20份、积雪草30份、独角莲20份、两头尖20份、对叶百部10份、枸杞子10份、甘草30份和仙人草30份制作而成。
一种前述的治疗便秘的药物的制作方法，取上述药物，可以加辅料，也可以不加辅料，制成口服制剂。
前述的治疗便秘的药物的制作方法所述口服制剂为颗粒剂、胶囊剂、片剂、丸剂、散剂或霜剂。
前述的治疗便秘的药物的制作方法所述颗粒剂这样制作：取上述药物，加10倍量水煎煮3次，每次1.5h，过滤，合并煎煮液，浓缩成50-60℃时相对密度为1.15-1.20的浸膏，浸膏与浸膏量20%的淀粉和20%的糊精粉混合制粒，干燥，即得。
前述的治疗便秘的药物的制作方法所述胶囊剂的制作方法为：取上述药物，用6倍量70%的乙醇回流提取2次，每次1小时，提取液过滤，滤液回收乙醇并浓缩成50-60℃时相对密度为1.20-1.25的浸膏，另取浸膏量30%的淀粉和0.7%的硬脂酸镁与浸膏混匀，用60%的乙醇制粒，干燥，粉碎，填充胶囊，即得。
前述的治疗便秘的药物的制作方法所述片剂的制作方法为：取上述药物，加10倍量水煎煮3次，每次1.5h，过滤，合并煎煮液，浓缩成50-60℃时相对密度为1.15-1.20的浸膏，浸膏与上述混合粉及浸膏量20%的淀粉混匀，压片，包薄膜衣，即得。
与现有技术相比，本发明所述药物主要由黄连、黄柏、苍术、积雪草、独角莲、两头尖、对叶百部、枸杞子、甘草和仙人草制作而成。处方中各原料具有很好的协同作用，制成的药物可用于治疗便秘；疗效显著，治疗周期短，安全无副作用。
具体实施方式：
实施例1.
配方：黄连20kg、黄柏10kg、苍术20kg、积雪草30kg、独角莲20kg、两头尖20kg、对叶百部10kg、枸杞子10kg、甘草30kg和仙人草30kg。
工艺：加10倍量水煎煮3次，每次1.5h，过滤，合并煎煮液，浓缩成50-60℃时相对密度为1.15-1.20的浸膏，浸膏与浸膏量20%的淀粉和20%的糊精粉混合制粒，干燥，即得颗粒剂。
规格：5g/袋。
用法用量：每次5-10g，每日2-3次。
实施例2.
配方：黄连20kg、黄柏10kg、苍术20kg、积雪草30kg、独角莲20kg、两头尖20kg、对叶百部10kg、枸杞子10kg、甘草30kg和仙人草30kg。
工艺：取上述药物，用6倍量70%的乙醇回流提取2次，每次1小时，提取液过滤，滤液回收乙醇并浓缩成50-60℃时相对密度为1.20-1.25的浸膏，另取浸膏量30%的淀粉和0.7%的硬脂酸镁与浸膏混匀，用60%的乙醇制粒，干燥，粉碎，填充胶囊，即得胶囊剂。
规格：0.3g/粒。
用法用量：每次5-10g，每日2-3次。
实施例3.
配方：黄连20kg、黄柏10kg、苍术20kg、积雪草30kg、独角莲20kg、两头尖20kg、对叶百部10kg、枸杞子10kg、甘草30kg和仙人草30kg。
工艺：取上述药物，加10倍量水煎煮3次，每次1.5h，过滤，合并煎煮液，浓缩成50-60℃时相对密度为1.15-1.20的浸膏，浸膏与上述混合粉及浸膏量20%的淀粉混匀，压片，包薄膜衣，即得片剂。
规格：0.3g/片。
用法用量：每次5-10g，每日2-3次。

Claims (8)

1.一种治疗便秘的药物，其特征在于：按重量份计算，主要由黄连10-30份、黄柏1-20份、苍术10-30份、积雪草20-40份、独角莲10-30份、两头尖10-30份、对叶百部1-20份、枸杞子1-20份、甘草20-40份和仙人草20-40份制作而成。
2.如权利要求1所述的治疗便秘的药物，其特征在于：按重量份计算，主要由黄连15-25份、黄柏5-15份、苍术15-25份、积雪草25-35份、独角莲15-25份、两头尖15-25份、对叶百部1-20份、枸杞子5-15份、甘草25-35份和仙人草25-35份制作而成。
3.如权利要求2所述的治疗便秘的药物，其特征在于：按重量份计算，主要由黄连20份、黄柏10份、苍术20份、积雪草30份、独角莲20份、两头尖20份、对叶百部10份、枸杞子10份、甘草30份和仙人草30份制作而成。
4.一种如权利要求1-3中任一项所述的治疗便秘的药物的制作方法，其特征在于：取上述药物，可以加辅料，也可以不加辅料，制成口服制剂。
5.如权利要求4所述的治疗便秘的药物的制作方法，其特征在于：所述口服制剂为颗粒剂、胶囊剂、片剂、丸剂、散剂或霜剂。
6.如权利要求5所述的治疗便秘的药物的制作方法，其特征在于：所述颗粒剂这样制作：取上述药物，加10倍量水煎煮3次，每次1.5h，过滤，合并煎煮液，浓缩成50-60℃时相对密度为1.15-1.20的浸膏，浸膏与浸膏量20%的淀粉和20%的糊精粉混合制粒，干燥，即得。
7.如权利要求5所述的治疗便秘的药物的制作方法，其特征在于：所述胶囊剂的制作方法为：取上述药物，用6倍量70%的乙醇回流提取2次，每次1小时，提取液过滤，滤液回收乙醇并浓缩成50-60℃时相对密度为1.20-1.25的浸膏，另取浸膏量30%的淀粉和0.7%的硬脂酸镁与浸膏混匀，用60%的乙醇制粒，干燥，粉碎，填充胶囊，即得。
8.如权利要求5所述的治疗便秘的药物的制作方法，其特征在于：所述片剂的制作方法为：取上述药物，加10倍量水煎煮3次，每次1.5h，过滤，合并煎煮液，浓缩成50-60℃时相对密度为1.15-1.20的浸膏，浸膏与上述混合粉及浸膏量20%的淀粉混匀，压片，包薄膜衣，即得。
CN201610918835.4A 2016-10-21 2016-10-21 一种治疗便秘的药物及其制作方法 Pending CN107970401A (zh)

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JP7160299B1 (ja) * 2021-03-23 2022-10-25 一丸ファルコス株式会社 粉末製剤及びその製造方法

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