CN107941553B - Handheld mechanical low-temperature sample sampling instrument - Google Patents
Handheld mechanical low-temperature sample sampling instrument Download PDFInfo
- Publication number
- CN107941553B CN107941553B CN201711397983.7A CN201711397983A CN107941553B CN 107941553 B CN107941553 B CN 107941553B CN 201711397983 A CN201711397983 A CN 201711397983A CN 107941553 B CN107941553 B CN 107941553B
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- Prior art keywords
- screw rod
- sampling
- cylinder body
- disc body
- pressing
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- 238000005070 sampling Methods 0.000 title claims abstract description 56
- 230000005540 biological transmission Effects 0.000 claims description 10
- 230000003014 reinforcing effect Effects 0.000 claims description 3
- 208000004067 Flatfoot Diseases 0.000 claims description 2
- 239000000523 sample Substances 0.000 abstract description 16
- 238000010257 thawing Methods 0.000 abstract description 10
- 239000012520 frozen sample Substances 0.000 abstract description 4
- 238000012423 maintenance Methods 0.000 abstract description 3
- 230000008014 freezing Effects 0.000 description 5
- 238000007710 freezing Methods 0.000 description 5
- 238000000034 method Methods 0.000 description 2
- 230000007547 defect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000010827 pathological analysis Methods 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
- G01N1/08—Devices for withdrawing samples in the solid state, e.g. by cutting involving an extracting tool, e.g. core bit
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention provides a handheld mechanical low-temperature sample sampling instrument which comprises a sampling drill needle, a support frame and a pressing rotating mechanism, wherein the support plate is fixed at the top of the support frame; a cylinder body is fixed above the supporting plate, and a disc body capable of freely sliding up and down along the inner wall of the cylinder body is arranged in the cylinder body; the bottom end of the screw rod is connected with the sampling drill needle, the top end of the screw rod is connected with the disc body, and the screw rod can freely rotate relative to the disc body; the top end of the disc body is connected with the lower pressure rod; the bottom end of the screw rod is provided with a limiting core body; the bottom of the sampling drill needle is a conical end with gradually reduced wall thickness, and a plurality of grooves are uniformly formed in the conical end. The invention can meet the repeated sampling requirement of users on frozen samples without freeze thawing, has higher operation safety and sampling efficiency, small volume, simple and convenient sampling operation, good stability, long service life and easy replacement and maintenance of parts.
Description
Technical Field
The invention belongs to the technical field of medical instruments, and particularly relates to a handheld mechanical low-temperature sample sampling instrument.
Background
Pathological diagnosis is a medical subject for studying the cause of disease, and sampling observation is a process that must be performed. After taking samples of human, animal and plant tissues in a laboratory, the samples are frozen and preserved at low temperature or ultra-low temperature, and when the samples are required to be used, the samples are frozen very firmly, and the sampling operation of the samples is very difficult. The conventional sampling method is thawing sampling or freezing and slicing, wherein thawing sampling requires thawing a sample, repeated freezing and thawing of the sample is required if sampling is performed at intervals, which can have a great influence on the quality of the sample, while freezing and slicing generally uses a freezing and slicing machine for performing related operations, and the slicing machine has a large volume and complicated operation steps.
Disclosure of Invention
In order to overcome the defects in the prior art, the invention provides a handheld mechanical low-temperature sample sampler which can conveniently sample frozen samples without freeze thawing, and has the advantages of small volume, compact design and easy operation.
The technical scheme adopted for solving the technical problems is as follows: the handheld mechanical low-temperature sample sampling instrument comprises a sampling drill needle, a supporting frame and a pressing rotating mechanism, wherein the supporting plate is fixed at the top of the supporting frame, the pressing rotating mechanism comprises a transmission piece and a screw rod, the transmission piece is fixed on the supporting plate, and screw teeth matched with the screw rod are arranged in the transmission piece; a cylinder body is fixed above the supporting plate, an end cover is arranged at the top of the cylinder body, a disc body capable of freely sliding up and down along the inner wall of the cylinder body is arranged in the cylinder body, and the outer diameter of the disc body is the same as the inner diameter of the cylinder body; the bottom end of the screw rod is connected with the sampling drill needle, the top end of the screw rod is connected with the disc body, and the screw rod can freely rotate relative to the disc body; the top end of the disc body is connected with a pressing rod which penetrates through the end cover and extends to the upper side of the cylinder body; the bottom end of the screw rod is provided with a limiting core body which extends downwards to the inside of the sampling drill needle; the bottom of the sampling drill needle is a conical end with gradually reduced wall thickness, and a plurality of grooves are uniformly formed in the conical end.
As a further preferred embodiment, the screw rod tip is connected to the disc body by means of a bearing.
As a further preferable embodiment, the bottom end of the screw rod is provided with a mounting hole, and the limiting core body is inserted into the mounting hole for fixation.
As a further preferred embodiment, the limiting core is made of plastic.
As a further preferred embodiment, the number of the slots is four and the slots are uniformly arranged around the tapered end.
As a further preferable implementation scheme, a plurality of reinforcing ribs are arranged between the supporting frame and the supporting plate.
As a further preferred embodiment, the support frame is cylindrical, and the support frame is provided with a viewing window.
As a further preferred embodiment, the bottom of the support frame is provided with a support flat.
As a further preferred embodiment, the top of the sampling drill needle is provided with a pintle which is in interference fit connection with the screw rod.
As a further preferable embodiment, the top end of the pressing rod is provided with a pressing plate.
The invention has the positive effects that: the invention can meet the repeated sampling requirement of users on frozen samples without freeze thawing, has higher operation safety and sampling efficiency, ensures the consistency of the quality of original samples and sampled samples and eliminates any potential hazard to the samples caused by freeze thawing by maintaining the frozen state sampling of the samples at ultralow temperature, and the invention has the advantages of small volume, compact and elegant design, easy storage and placement, simple and convenient sampling operation, good stability, long service life and easy replacement and maintenance of parts.
Drawings
FIG. 1 is a schematic view of a sampling apparatus according to a preferred embodiment;
FIG. 2 is a schematic view of the connection structure between the screw rod and the disc body according to the preferred embodiment;
FIG. 3 is a schematic view of the connection between the screw rod and the sampling drill point according to the preferred embodiment;
FIG. 4 is a schematic view of the bottom end structure of the sampling drill in accordance with the preferred embodiment;
fig. 5 is a schematic perspective view of the tapered end according to the preferred embodiment.
Detailed Description
The preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings.
Referring to fig. 1 to 5, a preferred embodiment of the present invention provides a handheld mechanical low-temperature sample sampler, which comprises a sampling drill needle 1, a support frame 2 and a pressing rotation mechanism, wherein the top of the support frame 2 is fixed with a support plate 3, the pressing rotation mechanism comprises a transmission member 14 and a screw rod 5, the transmission member 14 is fixed on the support plate 3, and screw teeth matched with the screw rod 5 are arranged in the transmission member 14; a cylinder body 4 is fixed above the supporting plate 3, an end cover 7 is arranged at the top of the cylinder body 4, a disc body 6 capable of freely sliding up and down along the inner wall of the cylinder body is arranged in the cylinder body 4, and the outer diameter of the disc body 6 is the same as the inner diameter of the cylinder body 4; the bottom end of the screw rod 5 is connected with the sampling drill needle 1, the top end of the screw rod 5 is connected with the disc body 6, and the screw rod 5 can freely rotate relative to the disc body 6; the top end of the disc body 6 is connected with a pressing rod 8, and the pressing rod 8 penetrates through the end cover 7 and extends above the cylinder body 4; the bottom end of the screw rod 5 is provided with a limiting core body 17, and the limiting core body 17 extends downwards to the inside of the sampling drill needle 1; the bottom end of the sampling drill needle 1 is a conical end 18 with gradually reduced wall thickness, and a plurality of grooves 19 are uniformly formed in the conical end 18.
As shown in fig. 2, the top end of the screw rod 5 is connected with the disc body 6 through a bearing 15.
As shown in fig. 3, a mounting hole is formed at the bottom end of the screw rod, and the limiting core 17 is inserted into the mounting hole to be fixed.
Preferably, the limiting core 17 is made of plastic.
As shown in fig. 5, the number of the slots 19 is four, and the slots 19 are uniformly arranged around the tapered end, and the width radian of each slot 19 is 15-20 degrees.
In order to further enhance the stability, a plurality of reinforcing ribs 11 are further arranged between the support frame 2 and the support plate 3.
Preferably, the supporting frame 2 is made of cylindrical stainless steel, and the supporting frame is provided with an observation window 12.
The bottom of the supporting frame is provided with a supporting flat foot 13.
As shown in fig. 3, the top of the sampling drill needle is provided with a pintle 16, and the pintle 16 and the screw rod 5 are fixedly connected through interference fit.
For the convenience of pressing or pushing down, the top end of the pushing rod 8 is provided with a pressing disc 9, and a grab handle 10 convenient for holding is arranged below the pressing disc.
Freezing the cylindrical support frame and the sampling drill point before sampling operation, so as to ensure that the sample is in a low-temperature environment in all links of the operation. The sampling instrument is placed on the sampling table during sampling operation, the frozen cylindrical supporting frame is utilized to surround a sampling sample, the position of the sampling instrument is adjusted to enable the sampling sample to be located under a sampling drill needle, then the pressing plate is pressed to enable the pressing rod to move downwards, meanwhile, the disc body moves downwards along the inner wall of the cylinder body, the spiral rod is matched with the transmission piece through the spiral rod, the spiral rod moves downwards and is in a rotating state, the sampling drill needle is in a rotating descending situation, the unique needle head structure can smoothly and efficiently rotate and drill the sample, the drilled tissue sample fills the space in the sampling drill needle, and the limiting core is used for limiting the maximum sampling amount, so that the sample is prevented from being contacted with the spiral rod, and the influence on sampling quality is avoided when different samples are taken.
The invention can meet the repeated sampling requirement of users on frozen samples without freeze thawing, has higher operation safety and sampling efficiency, ensures the consistency of the quality of original samples and sampled samples and eliminates any potential hazard to the samples caused by freeze thawing by maintaining the frozen state sampling of the samples at ultralow temperature, and the invention has the advantages of small volume, compact and elegant design, easy storage and placement, simple and convenient sampling operation and easy replacement and maintenance of parts.
The foregoing description of the preferred embodiments of the present invention has been presented only to facilitate the understanding of the principles of the invention and its core concepts, and is not intended to limit the scope of the invention in any way, however, any modifications, equivalents, etc. which fall within the spirit and principles of the invention should be construed as being included in the scope of the invention.
Claims (7)
1. The utility model provides a handheld mechanical type low temperature sample sampling instrument, includes sample drill point, its characterized in that: the device comprises a support frame, a pressing rotating mechanism and a pressing mechanism, wherein the support plate is fixed at the top of the support frame, the pressing rotating mechanism comprises a transmission piece and a screw rod, the transmission piece is fixed on the support plate, and screw teeth matched with the screw rod are arranged in the transmission piece; a cylinder body is fixed above the supporting plate, an end cover is arranged at the top of the cylinder body, a disc body capable of freely sliding up and down along the inner wall of the cylinder body is arranged in the cylinder body, and the outer diameter of the disc body is the same as the inner diameter of the cylinder body; the bottom end of the screw rod is connected with the sampling drill needle, the top end of the screw rod is connected with the disc body, and the screw rod can freely rotate relative to the disc body; the top end of the disc body is connected with a pressing rod which penetrates through the end cover and extends to the upper side of the cylinder body; the bottom end of the screw rod is provided with a limiting core body which extends downwards to the inside of the sampling drill needle; the bottom end of the sampling drill needle is a conical end with gradually reduced wall thickness, and a plurality of grooves are uniformly formed in the conical end;
the bottom end of the screw rod is provided with a mounting hole, and the limiting core body is inserted into the mounting hole for fixation; the top of the sampling drill needle is provided with a pintle which is in interference fit connection with the screw rod; the top of the pressing rod is provided with a pressing disc.
2. A hand-held mechanical cryogenic sample thief as claimed in claim 1, wherein: the top end of the spiral rod is connected with the disc body through a bearing.
3. A hand-held mechanical cryogenic sample thief as claimed in claim 1, wherein: the limiting core body is made of medical plastic.
4. A hand-held mechanical cryogenic sample thief according to claim 1 or 2, characterized in that: the number of the slots is four, and the slots are uniformly arranged around the conical end.
5. A hand-held mechanical cryogenic sample thief according to claim 1 or 2, characterized in that: a plurality of reinforcing ribs are arranged between the supporting frame and the supporting plate.
6. A hand-held mechanical cryogenic sample thief according to claim 1 or 2, characterized in that: the support frame is cylindrical, and an observation window is arranged on the support frame.
7. The hand-held, mechanical cryogenic sample thief of claim 6, wherein: the bottom of the supporting frame is provided with a supporting flat foot.
Priority Applications (1)
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CN201711397983.7A CN107941553B (en) | 2017-12-21 | 2017-12-21 | Handheld mechanical low-temperature sample sampling instrument |
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CN201711397983.7A CN107941553B (en) | 2017-12-21 | 2017-12-21 | Handheld mechanical low-temperature sample sampling instrument |
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CN107941553A CN107941553A (en) | 2018-04-20 |
CN107941553B true CN107941553B (en) | 2024-03-15 |
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CN201711397983.7A Active CN107941553B (en) | 2017-12-21 | 2017-12-21 | Handheld mechanical low-temperature sample sampling instrument |
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CN110686922B (en) * | 2019-10-10 | 2022-03-22 | 北京大学第一医院 | Split type low-temperature tissue divider |
Citations (8)
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---|---|---|---|---|
CN201325024Y (en) * | 2008-06-03 | 2009-10-14 | 唐朝勤 | Pressure-type drill hole or rotary screw device |
CN103076201A (en) * | 2013-01-09 | 2013-05-01 | 浙江省海洋水产研究所 | Spiral drilling type sampling device for frozen fish products |
CN103743588A (en) * | 2013-12-27 | 2014-04-23 | 中国人民解放军第四军医大学 | Tissue chip sampler |
CN106289860A (en) * | 2016-08-31 | 2017-01-04 | 山东山大附属生殖医院有限公司 | A kind of quick sampling device of biological sample |
CN106323682A (en) * | 2016-10-12 | 2017-01-11 | 广州市丹爵通讯科技有限公司 | Manual rotating type soil sampler |
CN106353131A (en) * | 2016-08-30 | 2017-01-25 | 中国科学院寒区旱区环境与工程研究所 | Frozen soil sampler |
CN206235479U (en) * | 2016-12-14 | 2017-06-09 | 信息产业部电子综合勘察研究院 | A kind of ground sampling hole device |
CN207964324U (en) * | 2017-12-21 | 2018-10-12 | 复旦大学附属肿瘤医院 | Mechanical hand-held low temperature sampling instrument |
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2017
- 2017-12-21 CN CN201711397983.7A patent/CN107941553B/en active Active
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN201325024Y (en) * | 2008-06-03 | 2009-10-14 | 唐朝勤 | Pressure-type drill hole or rotary screw device |
CN103076201A (en) * | 2013-01-09 | 2013-05-01 | 浙江省海洋水产研究所 | Spiral drilling type sampling device for frozen fish products |
CN103743588A (en) * | 2013-12-27 | 2014-04-23 | 中国人民解放军第四军医大学 | Tissue chip sampler |
CN106353131A (en) * | 2016-08-30 | 2017-01-25 | 中国科学院寒区旱区环境与工程研究所 | Frozen soil sampler |
CN106289860A (en) * | 2016-08-31 | 2017-01-04 | 山东山大附属生殖医院有限公司 | A kind of quick sampling device of biological sample |
CN106323682A (en) * | 2016-10-12 | 2017-01-11 | 广州市丹爵通讯科技有限公司 | Manual rotating type soil sampler |
CN206235479U (en) * | 2016-12-14 | 2017-06-09 | 信息产业部电子综合勘察研究院 | A kind of ground sampling hole device |
CN207964324U (en) * | 2017-12-21 | 2018-10-12 | 复旦大学附属肿瘤医院 | Mechanical hand-held low temperature sampling instrument |
Non-Patent Citations (2)
Title |
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建设部人事教育劳动司.《木工》.中国建筑工业出版社,1998,第97-98页. * |
月壤钻取与整形过程中样品层理保持特性分析;张利新;刘天喜;张鼐;王迎春;马亮;;航天器工程;20170415(02);第49-56页 * |
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