CN107929418A - A kind of nine steam the technological process of nine-processing radix rehmanniae preparata - Google Patents

A kind of nine steam the technological process of nine-processing radix rehmanniae preparata Download PDF

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Publication number
CN107929418A
CN107929418A CN201711008332.4A CN201711008332A CN107929418A CN 107929418 A CN107929418 A CN 107929418A CN 201711008332 A CN201711008332 A CN 201711008332A CN 107929418 A CN107929418 A CN 107929418A
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steam
time
dry
small
standard practice
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周青明
茹慈
梁斌
范九良
孙玉
许东亚
郭庆
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Anhui Hua Shan Tang Chinese Herbal Medicine Co Ltd
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Anhui Hua Shan Tang Chinese Herbal Medicine Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/13Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/17Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Fodder In General (AREA)

Abstract

The invention discloses the technological process that a kind of nine steam nine-processing radix rehmanniae preparata, following steps are specifically included:S1, neck material;S2, selection;S3, wash;S4, infusing drugs in wine;S5, steam for the first time;S6, for the first time drying;S7, mix for the first time;S8, steam for the second time;S9, second of drying;S10, mix for the second time;S11, steam for the third time;S12, third time are dry;S13, mix for the third time;S14, steam for the 4th time;S15, the 4th drying;S16, mix for the 4th time;S17, steam for the 5th time;S18, the 5th drying;S19, mix for the 5th time;S20, steam for the 6th time;S21, the 6th drying;S22, mix for the 6th time;S23, steam for the 7th time;S24, the 7th drying;S25, mix for the 7th time;S26, steam for the 8th time;S27, the 8th drying;S28, mix for the 8th time;S29, steam for the 9th time;S30, the 9th drying;S31, section;S32, the tenth drying;S33, packaging.The invention meets produce reality and the management requirement of GMP.

Description

A kind of nine steam the technological process of nine-processing radix rehmanniae preparata
Technical field
Invention is related to the process technology field of prepared rhizome of rehmannia, is specially a kind of nine technological processes for steaming nine-processing radix rehmanniae preparata.
Background technology
There is not the production technology code of the prepared rhizome of rehmannia of complete set also at present, make its production operation regulation and standardization, accord with The management requirement of our company's produce reality and GMP are closed, the product quality for ensureing to produce is homogeneous, the technique stream of prepared rhizome of rehmannia stablized Journey, therefore design a kind of technological process of nine steamings nine-processing radix rehmanniae preparata and be very necessary.
The content of the invention
The purpose of invention is to provide a kind of nine technological processes for steaming nine-processing radix rehmanniae preparata, to solve to propose mesh in above-mentioned background technology The production technology code of the preceding prepared rhizome of rehmannia for not having complete set also, makes its production operation regulation and standardization, meets our company's life The problem of production is actual and the management of GMP requirement, and the product quality for ensureing to produce is homogeneous, the technological process of the prepared rhizome of rehmannia stablized.
To achieve the above object, invention provides following technical solution:A kind of nine steam the technological process of nine-processing radix rehmanniae preparata, specifically Comprise the following steps:
S1, neck material:Lead material personnel to lead with material requistion to expect, neck is strictly checked when expecting, it is accurate to weigh;
S2, selection:Perform《Clean post standard practice instructions》, impurity is sorted out, is put in clean transfer container, is weighed;
S3, wash:Perform《Wash post standard practice instructions》And《Medicine-washing machine standard practice instructions》, wash post operation work Glutinous rehmannia is put into machine, with meet the water washing 3 times of drinking water standard to it is clean, without silt, load clean plastics transfer container;
S4, infusing drugs in wine:Radix rehmanniae recen after net system is placed in Turnround basket, adds appropriate yellow rice wine(Yellow rice wine amount is advisable for 30% medicinal material amount), leaching Profit is sucked for 2-4 hours to wine, and half an hour is stirred once;
S5, steam for the first time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer standard Operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, are passed through the steaming that pressure is 0.2-0.4Mpa Vapour about 8 stops steam one night of vexed profit when small, steam to inside and outside in black is moistened, pour out liquid and glutinous rehmannia that the inside steams;
S6, for the first time drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hours natural in threshing ground to eighty per cant dry or stand Shine near dry;
S7, mix for the first time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S8, steam for the second time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer standard Operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, are passed through the steaming that pressure is 0.2-0.4Mpa When vapour about 6 is small, stop the vexed profit 2 of steam it is small when, pour out the inside liquid and medicinal material that steam;
S9, second of drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hours natural in threshing ground to eighty per cant dry or stand Shine near dry;
S10, mix for the second time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S11, steam for the third time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer mark Quasi- operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, it is 0.2-0.4Mpa's to be passed through pressure When steam about 4 is small, stop the vexed profit 2 of steam it is small when, pour out the inside liquid and medicinal material that steam;
S12, third time are dry:Low temperature(55-60℃)Thickness:25-30mm, dry about n hour to eighty per cant dry or stand in threshing ground oneself So shine near dry;
S13, mix for the third time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S14, steam for the 4th time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer mark Quasi- operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, it is 0.2-0.4Mpa's to be passed through pressure When steam about 4 is small, stop the vexed profit 2 of steam it is small when, pour out the inside liquid and medicinal material that steam;
S15, the 4th drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hour to eighty per cant dry or stand in threshing ground oneself So shine near dry;
S16, mix for the 4th time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S17, steam for the 5th time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer mark Quasi- operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, it is 0.2-0.4Mpa's to be passed through pressure When steam about 4 is small, stop the vexed profit 2 of steam it is small when, pour out the inside liquid and medicinal material that steam;
S18, the 5th drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hour to eighty per cant dry or stand in threshing ground oneself So shine near dry;
S19, mix for the 5th time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S20, steam for the 6th time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer mark Quasi- operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, it is 0.2-0.4Mpa's to be passed through pressure When steam about 4 is small, stop the vexed profit 2 of steam it is small when, pour out the inside liquid and medicinal material that steam;
S21, the 6th drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hour to eighty per cant dry or stand in threshing ground oneself So shine near dry;
S22, mix for the 6th time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S23, steam for the 7th time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer mark Quasi- operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, it is 0.2-0.4Mpa's to be passed through pressure When steam about 4 is small, stop the vexed profit 2 of steam it is small when, pour out the inside liquid and medicinal material that steam;
S24, the 7th drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hour to eighty per cant dry or stand in threshing ground oneself So shine near dry;
S25, mix for the 7th time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S26, steam for the 8th time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer mark Quasi- operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, it is 0.2-0.4Mpa's to be passed through pressure When steam about 4 is small, stop the vexed profit 2 of steam it is small when, pour out the inside liquid and medicinal material that steam;
S27, the 8th drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hour to eighty per cant dry or stand in threshing ground oneself So shine near dry;
S28, mix for the 8th time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S29, steam for the 9th time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer mark Quasi- operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, it is 0.2-0.4Mpa's to be passed through pressure When steam about 4 is small, stop the vexed profit 2 of steam it is small when, pour out the liquid that steams of the inside and medicinal material mixed thoroughly;
S30, the 9th drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hours to six, seventy percent dry or stand in threshing ground Natural drying is to six, seventy percent dry;
S31, section:Perform《Cutting post standard practice instructions》《Flaking formula medicine cutter standard practice instructions》Cut sheet, thickness In 2 ~ 4mm, during cutting, thickness is cut to intermediate products every 20 minutes and is measured, and is recorded;
S32, the tenth drying:Perform《Dry post standard practice instructions》,《Heated-air circulation oven standard practice instructions》Or《It is spacious Mouth formula baking oven standard practice instructions》, 55-60 DEG C of design temperature, thickness:25-30mm, when the time, about n was small, dried moisture control System is within 15.0 ﹪;
S33, packaging:Pack, perform with packaging directive《Pack post standard practice instructions》, it is desirable to it is accurate to weigh, and sealing is tight, Without folder medicine, leakage medicine phenomenon, often pack and post the quality certification, quality certification content complete display.
Compared with prior art, advantageous effect of the invention is:The technological process of the nine steamings nine-processing radix rehmanniae preparata, can make prepared rhizome of rehmannia Production operation regulation and standardization, meet our company's produce reality and the management requirement of GMP, ensure the product matter produced Measure the technological process of prepared rhizome of rehmannia that is homogeneous, stablizing.
Brief description of the drawings
Fig. 1 is the technological process figure structure schematic representation of invention;
Fig. 2 is the computational methods and chemical limit scope schematic diagram of the material balance of invention;
Fig. 3 is the schematic diagram of invention quality Key Points of Monitoring.
Embodiment
Below in conjunction with the attached drawing in the embodiment of the present invention, the technical solution in the embodiment of the present invention is carried out clear, complete Site preparation describes, it is clear that described embodiment is only part of the embodiment of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, those of ordinary skill in the art are obtained every other without making creative work Embodiment, belongs to the scope of protection of the invention.
- 3 are please referred to Fig.1, invention provides a kind of technical solution:A kind of nine steam the technological process of nine-processing radix rehmanniae preparata, specific bag Include following steps:
S1, neck material:Lead material personnel to lead with material requistion to expect, neck is strictly checked when expecting, it is accurate to weigh;
S2, selection:Perform《Clean post standard practice instructions》, impurity is sorted out, is put in clean transfer container, is weighed;
S3, wash:Perform《Wash post standard practice instructions》And《Medicine-washing machine standard practice instructions》, wash post operation work Glutinous rehmannia is put into machine, with meet the water washing 3 times of drinking water standard to it is clean, without silt, load clean plastics transfer container;
S4, infusing drugs in wine:Radix rehmanniae recen after net system is placed in Turnround basket, adds appropriate yellow rice wine(Yellow rice wine amount is advisable for 30% medicinal material amount), leaching Profit is sucked for 2-4 hours to wine, and half an hour is stirred once;
S5, steam for the first time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer standard Operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, are passed through the steaming that pressure is 0.2-0.4Mpa Vapour about 8 stops steam one night of vexed profit when small, steam to inside and outside in black is moistened, pour out liquid and glutinous rehmannia that the inside steams;
S6, for the first time drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hours natural in threshing ground to eighty per cant dry or stand Shine near dry;
S7, mix for the first time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S8, steam for the second time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer standard Operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, are passed through the steaming that pressure is 0.2-0.4Mpa When vapour about 6 is small, stop the vexed profit 2 of steam it is small when, pour out the inside liquid and medicinal material that steam;
S9, second of drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hours natural in threshing ground to eighty per cant dry or stand Shine near dry;
S10, mix for the second time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S11, steam for the third time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer mark Quasi- operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, it is 0.2-0.4Mpa's to be passed through pressure When steam about 4 is small, stop the vexed profit 2 of steam it is small when, pour out the inside liquid and medicinal material that steam;
S12, third time are dry:Low temperature(55-60℃)Thickness:25-30mm, dry about n hour to eighty per cant dry or stand in threshing ground oneself So shine near dry;
S13, mix for the third time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S14, steam for the 4th time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer mark Quasi- operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, it is 0.2-0.4Mpa's to be passed through pressure When steam about 4 is small, stop the vexed profit 2 of steam it is small when, pour out the inside liquid and medicinal material that steam;
S15, the 4th drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hour to eighty per cant dry or stand in threshing ground oneself So shine near dry;
S16, mix for the 4th time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S17, steam for the 5th time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer mark Quasi- operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, it is 0.2-0.4Mpa's to be passed through pressure When steam about 4 is small, stop the vexed profit 2 of steam it is small when, pour out the inside liquid and medicinal material that steam;
S18, the 5th drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hour to eighty per cant dry or stand in threshing ground oneself So shine near dry;
S19, mix for the 5th time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S20, steam for the 6th time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer mark Quasi- operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, it is 0.2-0.4Mpa's to be passed through pressure When steam about 4 is small, stop the vexed profit 2 of steam it is small when, pour out the inside liquid and medicinal material that steam;
S21, the 6th drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hour to eighty per cant dry or stand in threshing ground oneself So shine near dry;
S22, mix for the 6th time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S23, steam for the 7th time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer mark Quasi- operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, it is 0.2-0.4Mpa's to be passed through pressure When steam about 4 is small, stop the vexed profit 2 of steam it is small when, pour out the inside liquid and medicinal material that steam;
S24, the 7th drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hour to eighty per cant dry or stand in threshing ground oneself So shine near dry;
S25, mix for the 7th time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S26, steam for the 8th time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer mark Quasi- operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, it is 0.2-0.4Mpa's to be passed through pressure When steam about 4 is small, stop the vexed profit 2 of steam it is small when, pour out the inside liquid and medicinal material that steam;
S27, the 8th drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hour to eighty per cant dry or stand in threshing ground oneself So shine near dry;
S28, mix for the 8th time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S29, steam for the 9th time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer mark Quasi- operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, it is 0.2-0.4Mpa's to be passed through pressure When steam about 4 is small, stop the vexed profit 2 of steam it is small when, pour out the liquid that steams of the inside and medicinal material mixed thoroughly;
S30, the 9th drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hours to six, seventy percent dry or stand in threshing ground Natural drying is to six, seventy percent dry;
S31, section:Perform《Cutting post standard practice instructions》《Flaking formula medicine cutter standard practice instructions》Cut sheet, thickness In 2 ~ 4mm, during cutting, thickness is cut to intermediate products every 20 minutes and is measured, and is recorded;
S32, the tenth drying:Perform《Dry post standard practice instructions》,《Heated-air circulation oven standard practice instructions》Or《It is spacious Mouth formula baking oven standard practice instructions》, 55-60 DEG C of design temperature, thickness:25-30mm, when the time, about n was small, dried moisture control System is within 15.0 ﹪;
S33, packaging:Pack, perform with packaging directive《Pack post standard practice instructions》, it is desirable to it is accurate to weigh, and sealing is tight, Without folder medicine, leakage medicine phenomenon, often pack and post the quality certification, quality certification content complete display.
Advantageous effect of the invention is:The technological process of the nine steamings nine-processing radix rehmanniae preparata, can make the production operation specification of prepared rhizome of rehmannia Change, standardization, meet our company's produce reality and the management requirement of GMP, the product quality for ensureing to produce is homogeneous, it is ripe to stablize The technological process of glutinous rehmannia.
Obviously, various changes and modifications can be made to the invention without departing from essence of the invention by those skilled in the art God and scope.In this way, if these modifications and changes of the present invention belongs to the scope of the claims in the present invention and its equivalent technologies Within, then the present invention is also intended to comprising including these modification and variations.

Claims (1)

1. a kind of nine steam the technological process of nine-processing radix rehmanniae preparata, it is characterised in that specifically include following steps:
S1, neck material:Lead material personnel to lead with material requistion to expect, neck is strictly checked when expecting, it is accurate to weigh;
S2, selection:Perform《Clean post standard practice instructions》, impurity is sorted out, is put in clean transfer container, is weighed;
S3, wash:Perform《Wash post standard practice instructions》And《Medicine-washing machine standard practice instructions》, wash post operation work Glutinous rehmannia is put into machine, with meet the water washing 3 times of drinking water standard to it is clean, without silt, load clean plastics transfer container;
S4, infusing drugs in wine:Radix rehmanniae recen after net system is placed in Turnround basket, adds appropriate yellow rice wine(Yellow rice wine amount is advisable for 30% medicinal material amount), leaching Profit is sucked for 2-4 hours to wine, and half an hour is stirred once;
S5, steam for the first time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer standard Operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, are passed through the steaming that pressure is 0.2-0.4Mpa Vapour about 8 stops steam one night of vexed profit when small, steam to inside and outside in black is moistened, pour out liquid and glutinous rehmannia that the inside steams;
S6, for the first time drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hours natural in threshing ground to eighty per cant dry or stand Shine near dry;
S7, mix for the first time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S8, steam for the second time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer standard Operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, are passed through the steaming that pressure is 0.2-0.4Mpa When vapour about 6 is small, stop the vexed profit 2 of steam it is small when, pour out the inside liquid and medicinal material that steam;
S9, second of drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hours natural in threshing ground to eighty per cant dry or stand Shine near dry;
S10, mix for the second time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S11, steam for the third time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer mark Quasi- operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, it is 0.2-0.4Mpa's to be passed through pressure When steam about 4 is small, stop the vexed profit 2 of steam it is small when, pour out the inside liquid and medicinal material that steam;
S12, third time are dry:Low temperature(55-60℃)Thickness:25-30mm, dry about n hour to eighty per cant dry or stand in threshing ground oneself So shine near dry;
S13, mix for the third time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S14, steam for the 4th time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer mark Quasi- operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, it is 0.2-0.4Mpa's to be passed through pressure When steam about 4 is small, stop the vexed profit 2 of steam it is small when, pour out the inside liquid and medicinal material that steam;
S15, the 4th drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hour to eighty per cant dry or stand in threshing ground oneself So shine near dry;
S16, mix for the 4th time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S17, steam for the 5th time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer mark Quasi- operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, it is 0.2-0.4Mpa's to be passed through pressure When steam about 4 is small, stop the vexed profit 2 of steam it is small when, pour out the inside liquid and medicinal material that steam;
S18, the 5th drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hour to eighty per cant dry or stand in threshing ground oneself So shine near dry;
S19, mix for the 5th time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S20, steam for the 6th time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer mark Quasi- operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, it is 0.2-0.4Mpa's to be passed through pressure When steam about 4 is small, stop the vexed profit 2 of steam it is small when, pour out the inside liquid and medicinal material that steam;
S21, the 6th drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hour to eighty per cant dry or stand in threshing ground oneself So shine near dry;
S22, mix for the 6th time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S23, steam for the 7th time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer mark Quasi- operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, it is 0.2-0.4Mpa's to be passed through pressure When steam about 4 is small, stop the vexed profit 2 of steam it is small when, pour out the inside liquid and medicinal material that steam;
S24, the 7th drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hour to eighty per cant dry or stand in threshing ground oneself So shine near dry;
S25, mix for the 7th time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S26, steam for the 8th time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer mark Quasi- operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, it is 0.2-0.4Mpa's to be passed through pressure When steam about 4 is small, stop the vexed profit 2 of steam it is small when, pour out the inside liquid and medicinal material that steam;
S27, the 8th drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hour to eighty per cant dry or stand in threshing ground oneself So shine near dry;
S28, mix for the 8th time:When mixing infiltration thoroughly by first time distillate and dried medicinal material about 2-4 is small, half an hour stirs one It is secondary;
S29, steam for the 9th time:Perform《Steam post standard practice instructions》And《Digester standard practice instructions》Or《Food steamer mark Quasi- operational procedure》, middle product are put into tilting-type digester or are uniformly inserted in food steamer, it is 0.2-0.4Mpa's to be passed through pressure When steam about 4 is small, stop the vexed profit 2 of steam it is small when, pour out the liquid that steams of the inside and medicinal material mixed thoroughly;
S30, the 9th drying:Low temperature(55-60℃)Thickness:25-30mm, dry about n hours to six, seventy percent dry or stand in threshing ground Natural drying is to six, seventy percent dry;
S31, section:Perform《Cutting post standard practice instructions》《Flaking formula medicine cutter standard practice instructions》Cut sheet, thickness In 2 ~ 4mm, during cutting, thickness is cut to intermediate products every 20 minutes and is measured, and is recorded;
S32, the tenth drying:Perform《Dry post standard practice instructions》,《Heated-air circulation oven standard practice instructions》Or《It is spacious Mouth formula baking oven standard practice instructions》, 55-60 DEG C of design temperature, thickness:25-30mm, when the time, about n was small, dried moisture control System is within 15.0 ﹪;
S33, packaging:Pack, perform with packaging directive《Pack post standard practice instructions》, it is desirable to it is accurate to weigh, and sealing is tight, Without folder medicine, leakage medicine phenomenon, often pack and post the quality certification, quality certification content complete display.
CN201711008332.4A 2017-10-25 2017-10-25 A kind of nine steam the technological process of nine-processing radix rehmanniae preparata Pending CN107929418A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108498630A (en) * 2018-06-16 2018-09-07 禹州市厚生堂中药有限公司 A kind of Chinese medicine preparation production technology
CN108938812A (en) * 2018-08-23 2018-12-07 陕西广济堂医药集团股份有限公司 A kind of production method of Rehmannia glutinosa purification medicine materical crude slice
CN110237148A (en) * 2019-07-22 2019-09-17 河南尚华堂药业股份有限公司 A kind of Rehmannia glutinosa production technology
CN114796347A (en) * 2022-04-29 2022-07-29 通渭县昌源药业有限公司 Processing method and detection method of prepared rehmannia root

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20090048119A (en) * 2007-11-09 2009-05-13 (주)한마루 Making manufacture of black ginseng and the black ginseng
CN101518590A (en) * 2009-03-24 2009-09-02 朱清山 Preparation method of prepared radix rehmannia steamed and dried for nine times
CN107213249A (en) * 2017-04-26 2017-09-29 安徽华善堂中药饮片有限公司 Nine steam the processing procedure method of nine-processing radix rehmanniae preparata

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20090048119A (en) * 2007-11-09 2009-05-13 (주)한마루 Making manufacture of black ginseng and the black ginseng
CN101518590A (en) * 2009-03-24 2009-09-02 朱清山 Preparation method of prepared radix rehmannia steamed and dried for nine times
CN107213249A (en) * 2017-04-26 2017-09-29 安徽华善堂中药饮片有限公司 Nine steam the processing procedure method of nine-processing radix rehmanniae preparata

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108498630A (en) * 2018-06-16 2018-09-07 禹州市厚生堂中药有限公司 A kind of Chinese medicine preparation production technology
CN108938812A (en) * 2018-08-23 2018-12-07 陕西广济堂医药集团股份有限公司 A kind of production method of Rehmannia glutinosa purification medicine materical crude slice
CN110237148A (en) * 2019-07-22 2019-09-17 河南尚华堂药业股份有限公司 A kind of Rehmannia glutinosa production technology
CN114796347A (en) * 2022-04-29 2022-07-29 通渭县昌源药业有限公司 Processing method and detection method of prepared rehmannia root

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Application publication date: 20180420