CN107929113A - Antipollution skin care compositions and cosmetics - Google Patents

Antipollution skin care compositions and cosmetics Download PDF

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Publication number
CN107929113A
CN107929113A CN201711447788.0A CN201711447788A CN107929113A CN 107929113 A CN107929113 A CN 107929113A CN 201711447788 A CN201711447788 A CN 201711447788A CN 107929113 A CN107929113 A CN 107929113A
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China
Prior art keywords
skin
antipollution
care compositions
antipollution skin
skin care
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Application number
CN201711447788.0A
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Chinese (zh)
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CN107929113B (en
Inventor
林立宇
蒲源
邹威
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Sejong Innovation (Guangzhou) Health Industry Co., Ltd.
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Zhi Yuan Bio Tech Ltd Guangzhou
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/733Alginic acid; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Cosmetics (AREA)

Abstract

The present invention relates to a kind of antipollution skin care compositions and cosmetics.The antipollution skin care compositions includes matrix, and the component of following percentage by weight:Chlorella extract 1.5~3%, trehalose 2~6%, dimethyl methyl epoxide benzodihydropyran alcohol 1~3%.The effect of antipollution skin care compositions can be effectively formed skin antipollution barrier, improve tolerance of the skin to stimulant, deep layer purification skin PM2.5, improve skin oxidation resistance, repair cell and DNA damage, and can be to uvioresistant to skin injury.

Description

Antipollution skin care compositions and cosmetics
Technical field
The present invention relates to cosmetics, more particularly to antipollution skin care compositions and cosmetics.
Background technology
As production and economic express delivery increase, the continuous deterioration of environment, air pollution constantly aggravates, the pollution of the mankind Source is constantly increasing.Pollution can cause adverse reaction, and trigger serious problems, such case in the big city in Asia more so.
The material of pollution is formed to air and water includes gaseous material, organic compound, heavy metal and particulate matter.It is exposed to In these materials, cause the generation of response to oxidative stress, and some disadvantageous changes can be brought, including Skin Cell survival ability drop Low, metallothionein overexpression, metallothionein can be to anti-metal and oxidant, and reduces cell of Langerhan in immune system Quantity, such damage can cause skin that obvious change, such as dry, red and swollen and premature aging occurs.In addition, UVB also can be to skin Skin causes to damage.
In presently commercially available cosmetics, only few portioned product has effects that resistant to pollution, and antipollution effect is main Concentrate on cleaning skin, complexing heavy metal etc., it is more difficult to antipollution protection, and deep layer purification and reparation are carried out to skin.
The content of the invention
Based on this, it is necessary to provide a kind of antipollution skin care compositions, which can be effectively formed Skin antipollution barrier, reduces pollutant attachment on the skin;Barrier effect of skin is lifted, strengthens skin to the resistance to of stimulant Stress;The effect of deep layer purification skin PM2.5, raising skin oxidation resistance, repair cell and DNA damage, and can resist Ultraviolet is to skin injury.
A kind of antipollution skin care compositions, including matrix, and the component of following percentage by weight:
Chlorella extract 1.5~3%
Trehalose 2~6%
Dimethyl methyl epoxide benzodihydropyran alcohol 1~3%.
Matrix of the present invention can be the Conventional solvents or auxiliary agent used in cosmetics or skin care item, as water, moisturizer, Emollient, thickener, emulsifying agent etc..
In one of the embodiments, the antipollution skin care compositions, including matrix, and following percentage by weight Component:
Chlorella extract 2.5~3%
Trehalose 2~3%
Dimethyl methyl epoxide benzodihydropyran alcohol 1~2%.
The present invention also provides application of the antipollution skin care compositions in cosmetics.
The present invention also provides a kind of antipollution skin protection cosmetics, with percentage by weight, including the following raw material component:
In one of the embodiments, the antipollution skin protection cosmetics, with percentage by weight, including the following raw material group Point:
In one of the embodiments, the moisturizer includes glycerine and pungent glycol.It is preferred that the weight ratio of the two is 5~8: 0.1。
In one of the embodiments, the emollient includes ring five dimethyl silicone polymer, the poly- trimethyl silica of phenyl Alkane and octyl group polymethyl siloxane.It is preferred that the weight ratio of three is 8~16:5~12:1~5.
In one of the embodiments, the thickener includes beeswax and distearyl dimethylammonium hectorite.It is preferred that the two Weight ratio be 0.5~2:3~5.
In one of the embodiments, the emulsifying agent includes PEG-10 Polydimethylsiloxane and polyglycereol -3 two is different hard Resin acid ester.It is preferred that the weight ratio of the two is 1~1.8:0.3~0.7.
In one of the embodiments, to account for the percentage by weight agent of the raw material components, the function additive includes:
In one of the embodiments, the antifreeze is sodium chloride;Oil-control component is silica;The preservative is benzene oxygen Ethanol and/or Sensiva SC50.
The principle of the present invention and advantage are as follows:
The antipollution skin care compositions of the present invention, using chlorella extract, trehalose and dimethyl methyl epoxide benzo two Hydrogen pyrans alcohol is engaged, wherein:
The raw material pellet algae of chlorella (CHLORELLA VULGARIS) extract is that one kind can adapt to polar region and high mountain The monoplast green alga of the extreme environments such as snowfield, it can resist the stress bar such as low temperature, bloom photograph, strong ultraviolet radioactive, high salt, poor nutrition Part, the change of its intracellular lipid, the especially synthesis of film fat and aliphatic acid and the degraded lifting in cell metabolism adjusting, Resistance Physiology Act on, and the synthesis of other non-fat micromolecular metabolins adjusts the sheet that even more decide cell adapted extreme environment with decomposing Matter feature and inherent mechanism.Chlorella relies primarily under this extremity synthesizes special cell component to adapt to extreme ring Border and Conservative restoration cell and DNA damage, the oxidative damage of membrane lipid and enzyme, including carotenoid, C.G.F, exocellular polysaccharide, Aldehydes matter and Proline etc..The active ingredient (chlorella deep layer purification factor CPEs) extracted from chlorella exists The oxidative damage of Conservative restoration skin cell and DNA damage, membrane lipid and enzyme can equally be reached after being absorbed by human skin Effect." glycoprotein " component --- the chlorella growth factor that chlorella (CHLORELLA VULGARIS) extract contains (C.G.F), this unique active material being made of small molecular sugar and protein peptides can still be protected under a variety of extreme conditions Activity is held, there is multiple skin-care effect after Transdermal absorption:Deep layer purifies skin PM2.5, repair cell and DNA damage, and confrontation is purple Outer damage.
On the basis of using chlorella extract, with reference to trehalose and dimethyl methyl epoxide benzodihydropyran alcohol:Sea Algae sugar has the excellent characteristic for keeping cell viability and large biological molecule activity, and dimethyl methyl epoxide benzodihydropyran alcohol can With the framework antipollution barrier between skin and ambient contamination thing, thus one can be formed in cell surface layer in the case of severe The special protective film of layer, chlorella extract lock in skin surface and is played its excellent purification, repaired the effect of skin, and Antipollution barrier is established between skin and pollutant:
First, complexing PM2.5 is adsorbed in skin surface, prevents top layer sebum from aoxidizing, reduction first layer injury;Secondly, energy Enough make the expression increase of cuticula silk polyprotein, keratinocytes prevent damage of the pollutant PM2.5 particles to skin barrier, right Anti- second layer injury;Can also activating macrophage phagocytic activity, the PM2.5 that can largely swallow through stratum corneum barrier keeps away Exempt from scytitis generation, that is, prevent third layer from injuring;Permeable skin barrier reaches the cell and cell that basalis reparation is damaged DNA, prevents skin aging and deep layer injury, that is, prevents four layer injuries of the PM2.5 to skin;For damages of the UVB to skin, 60% cellular damage due to induced by ultraviolet irradiation can be significantly improved, is repaired because ultraviolet stimulates the sunburn erythema produced.
In addition, trehalose is by replacing the moisture in tissue to protect skin fibroblasts to prevent from being dehydrated, it can subtract Injury caused by few dehydration, cold and hot change, so as to keep the natural structure of skin, can protect cell because of climate change and possibility The injury being subjected to, being shared with chlorella extract helps to maintain cell viability, and can keep skin molds, reduces damage Evil trace, improves the skin repair effect of the antipollution skin care compositions.Meanwhile the mucus separated out from protective film is not only moistened Skin Cell, also has the function of external heat radiateing, so as to protect skin to be damaged, and is strengthened anti-oxidant Phylactic power defensive power, resists oxidative stress.And dimethyl methyl epoxide benzodihydropyran alcohol also have the function that metal-chelating and it is potent from By base scavenger, pollutant injury is further protected the skin from.
Thus, antipollution skin care compositions of the invention, collaboration use chlorella extract, trehalose and dimethyl methoxy Base benzodihydropyran alcohol can be effectively formed skin antipollution barrier, lift barrier effect of skin, reduce pollutant attachment On the skin, tolerance of the skin to stimulant is strengthened, deep layer purification skin PM2.5, improves skin oxidation resistance, repair thin Born of the same parents and the effect of DNA damage, and can be to uvioresistant to skin injury.
The antipollution skin protection cosmetics of the present invention, using above-mentioned antipollution skin care compositions, and further combined with suitable Raw material components compatibility, it is possible to increase above-mentioned attachment of the antipollution skin care compositions in skin surface and the infiltration to skin, optimization Its antipollution, reparation and improve the effect of skin is to the tolerance of stimulant.
Brief description of the drawings
Fig. 1 is that road assists diligent personnel using 3 antipollution skin care compositions (right figure) of embodiment and the skin of hand of water (left figure) Contrast photo (10 times of amplification).
Embodiment
Further details of theory is made to the antipollution skin care compositions and cosmetics of the present invention below in conjunction with specific embodiment It is bright.
The raw material used in the embodiment of the present invention is as follows:
Chlorella extract (Chlorella Ecust CPEs) is purchased from Shanghai Jia Yu bio tech ltd, its is main Component is chlorella extract, remaining also has proper amount of matrix, and matrix includes G & W.
Trehalose (TREHALOSE 100) is purchased from Lin Yuan companies of Japan.
Dimethyl methyl epoxide benzodihydropyran alcohol (pollushield) is purchased from Lubrizol companies of the U.S., its mainly into It is divided into dimethyl methyl epoxide benzodihydropyran alcohol, remaining also has proper amount of matrix, and it is different that matrix includes water, propane diols, adipic acid two Propyl ester, lecithin, acrylic acid/acrylamide methyl propane sulfonic acid copolymer, glycerol caprylate and xanthans.
Distearyl dimethylammonium hectorite is purchased from bentone, trade mark VS5-PCV, its main component is distearyl dimethylammonium Hectorite, remaining also has proper amount of matrix, and matrix includes ring five dimethyl silicone polymer, propylene glycol carbonate.
Embodiment 1-3
Three kinds of antipollution skin care compositions of the present embodiment, including matrix, and the component (table 1) of following percentage by weight:
Table 1
Above-mentioned antipollution skin care compositions preparation method is conventionally mixing.
Embodiment 4-6
Three kinds of antipollution skin protection cosmetics (foundation emulsion) of the present embodiment, by weight percentage, three kinds of antipollution skin cares Cosmetic includes following component (table 2) respectively:
Table 2
The preparation method of above-mentioned antipollution skin protection cosmetics, includes the following steps:
(1) component in component A is added in water phase pot, opens stirring, be warming up to 80 DEG C, 10 minutes are kept the temperature, until complete Fully dissolved;
(2) mixing speed for emulsifying pot is maintained at 30 revs/min, and component A is passed through vacuum suck, low speed homogeneous 5 minutes;
(3) raw material of B component is sequentially added in oil phase pot, is then heated to 80 DEG C, then delay B component by vacuum In slow suction emulsification pot, stirring, low speed homogeneous 10 minutes are opened;
(4) component C is added in emulsification pot, low speed homogeneous 5 minutes, cooling;
(5) 45 DEG C are cooled to and, adds D phases, low speed homogeneous 5 minutes;
(6) when stirring is down to 40 DEG C, E phases, low speed homogeneous 5 minutes, discharging are added.
Comparative example 1
A kind of antipollution skin protection cosmetics of this comparative example, its raw material and preparation method similar embodiment 4, difference lies in:Not Using the trehalose.
Comparative example 2
A kind of antipollution skin protection cosmetics of this comparative example, its raw material and preparation method similar embodiment 4, difference lies in:Not Using the dimethyl methyl epoxide benzodihydropyran alcohol.
First, the attachment test of Pollution protection thing is carried out to the antipollution skin care compositions of embodiment 1-3
Test method:
10 diligent personnel of road association of selection, both hands are cleaned up, dried with paper handkerchief with hand cleanser.On the ground of left hand the back of the hand Side, coats the antipollution skin care compositions of 0.3 gram of embodiment 1-3 on about 2 square centimeters of area;In its right hand the back of the hand Place, water (control sample) is coated on about 2 square centimeters of area.Then ask them 3 on duty small on road side When, the contaminated situation of hand skin is then observed in the case where amplifying 10 times.
Test result:
The diligent personnel of road association smear right hand skin of the left hand skin of embodiment 1-3 antipollution skin care compositions with smearing water Compare, the degree and quantity for adhering to dirt significantly reduce.Diligent personnel of road association of embodiment 3 or so skin of hand contrast photo is such as Shown in Fig. 1 (10 times of amplification).The antipollution skin care compositions can prevent dust to be attached to skin it can be seen from experimental result On skin, there is the effect of resistance air pollution.
2nd, the tolerance of the progress stimulant of the antipollution skin protection cosmetics of embodiment 4-6 and comparative example 1-2 is tested
Test method:
Choosing 50 has lactic acid anaphylactoid subject, is randomly divided into 5 groups, and after subject's face cleaning, left side cheek applies The cosmetics that 4-6 of the embodiment of the present invention and comparative example 1-2 are prepared are smeared, right cheek is smeared corresponding cosmetic base and (is free of Chlorella extract, trehalose, dimethyl methyl epoxide benzodihydropyran alcohol), 4 weeks laggard assassinate of continuous use swash test, i.e., Take 0.2 gram of 10% lactic acid solution to be applied to left and right cheek, carry out dermoreaction assessment, evaluation criteria is as follows:
0 point:Without tingling sensation
1 point:Slight shouting pain
2 points:Moderate shouting pain
3 points:Fever, erythema or redness.
Test result:As shown in table 3.
Table 3
The right cheek Left side cheek With respect to slip %
Embodiment 4 2.1 1.6 23.8%
Embodiment 5 2.4 1.7 29.2%
Embodiment 6 2.0 1.3 35%
Comparative example 1 2.8 2.5 10.7%
Comparative example 2 2.5 2.2 12%
Relative to common skin care item it can be seen from the result of upper table, the antipollution cosmetics of embodiment 4-6 are smeared Skin, uncomfortable degree declines after stimulated, illustrates the antipollution cosmetics of the present invention and can significantly improve skin to stimulant Tolerance.
Each technical characteristic of embodiment described above can be combined arbitrarily, to make description succinct, not to above-mentioned reality Apply all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited In contradiction, the scope that this specification is recorded all is considered to be.
Embodiment described above only expresses the several embodiments of the present invention, its description is more specific and detailed, but simultaneously Cannot therefore it be construed as limiting the scope of the patent.It should be pointed out that come for those of ordinary skill in the art Say, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the protection of the present invention Scope.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.

Claims (10)

  1. A kind of 1. antipollution skin care compositions, it is characterised in that including matrix, and the component of following percentage by weight:
    Chlorella extract 1.5~3%
    Trehalose 2~6%
    Dimethyl methyl epoxide benzodihydropyran alcohol 1~3%.
  2. 2. antipollution skin care compositions according to claim 1, it is characterised in that including matrix, and following weight hundred Divide the component of ratio:
    Chlorella extract 2.5~3%
    Trehalose 2~3%
    Dimethyl methyl epoxide benzodihydropyran alcohol 1~2%.
  3. 3. application of the antipollution skin care compositions in cosmetics described in claim 1 or 2.
  4. 4. a kind of antipollution skin protection cosmetics, it is characterised in that with percentage by weight, including the following raw material component:
  5. 5. antipollution skin protection cosmetics according to claim 4, it is characterised in that with percentage by weight, including it is following former Expect component:
  6. 6. antipollution skin protection cosmetics according to claim 4, it is characterised in that the moisturizer includes glycerine and Xin Gan Alcohol.
  7. 7. antipollution skin protection cosmetics according to claim 4, it is characterised in that the emollient includes five poly- diformazan of ring Radical siloxane, phenyl trimethicone and octyl group polymethyl siloxane.
  8. 8. antipollution skin protection cosmetics according to claim 4, it is characterised in that the thickener is hard including beeswax and two Fat dimethylammonium hectorite.
  9. 9. antipollution skin protection cosmetics according to claim 4, it is characterised in that the emulsifying agent includes PEG-10 poly- two Methylsiloxane and polyglyceryl-3 diisostearate.
  10. 10. according to claim 4-9 any one of them antipollution skin protection cosmetics, it is characterised in that to account for the raw material group The percentage by weight agent divided, the function additive include:
CN201711447788.0A 2017-12-27 2017-12-27 Anti-pollution skin care composition and cosmetic Active CN107929113B (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109394618A (en) * 2018-11-27 2019-03-01 东莞市润孚化妆品有限公司 A kind of antiallergy reparation skin-care agent
CN109549893A (en) * 2019-01-22 2019-04-02 广州睿森生物科技有限公司 A kind of preparation method with anti-blue light contamination and the composition repaired and essence cream and its essence cream
CN110464676A (en) * 2018-05-10 2019-11-19 味丹生物科技股份有限公司 Active constituent includes the cosmetic composition of gamma-polyglutamic acid

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US5883243A (en) * 1995-02-10 1999-03-16 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Non-reducing saccharides, their preparations and uses
JP2011173851A (en) * 2010-02-25 2011-09-08 Kazki International:Kk Patch for beautification
CN105055261A (en) * 2015-09-15 2015-11-18 广州智媛生物科技有限公司 Anti-pollution skincare product and preparation method thereof
CN106236623A (en) * 2016-07-29 2016-12-21 上海伽誉生物科技有限公司 The preparation method of chlorella deep layer purification factor
CN106562901A (en) * 2016-11-02 2017-04-19 广州市巧美化妆品有限公司 Preparation method of hot spring chlorella extract product solution applied to cosmetics
CN106806255A (en) * 2017-02-11 2017-06-09 佛山市芊茹化妆品有限公司 A kind of antipollution mask
CN107184411A (en) * 2017-04-21 2017-09-22 韩后化妆品股份有限公司 A kind of preparation method of the tender factor of Compound Water, cosmetics and cosmetics

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5883243A (en) * 1995-02-10 1999-03-16 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Non-reducing saccharides, their preparations and uses
JP2011173851A (en) * 2010-02-25 2011-09-08 Kazki International:Kk Patch for beautification
CN105055261A (en) * 2015-09-15 2015-11-18 广州智媛生物科技有限公司 Anti-pollution skincare product and preparation method thereof
CN106236623A (en) * 2016-07-29 2016-12-21 上海伽誉生物科技有限公司 The preparation method of chlorella deep layer purification factor
CN106562901A (en) * 2016-11-02 2017-04-19 广州市巧美化妆品有限公司 Preparation method of hot spring chlorella extract product solution applied to cosmetics
CN106806255A (en) * 2017-02-11 2017-06-09 佛山市芊茹化妆品有限公司 A kind of antipollution mask
CN107184411A (en) * 2017-04-21 2017-09-22 韩后化妆品股份有限公司 A kind of preparation method of the tender factor of Compound Water, cosmetics and cosmetics

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110464676A (en) * 2018-05-10 2019-11-19 味丹生物科技股份有限公司 Active constituent includes the cosmetic composition of gamma-polyglutamic acid
CN109394618A (en) * 2018-11-27 2019-03-01 东莞市润孚化妆品有限公司 A kind of antiallergy reparation skin-care agent
CN109549893A (en) * 2019-01-22 2019-04-02 广州睿森生物科技有限公司 A kind of preparation method with anti-blue light contamination and the composition repaired and essence cream and its essence cream

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