CN107928782B - Electrode device for inactivating tumor cells in esophageal wall and using method thereof - Google Patents
Electrode device for inactivating tumor cells in esophageal wall and using method thereof Download PDFInfo
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- CN107928782B CN107928782B CN201711420775.4A CN201711420775A CN107928782B CN 107928782 B CN107928782 B CN 107928782B CN 201711420775 A CN201711420775 A CN 201711420775A CN 107928782 B CN107928782 B CN 107928782B
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- Prior art keywords
- propelling movement
- tube
- electrode
- screens
- pushing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00214—Expandable means emitting energy, e.g. by elements carried thereon
- A61B2018/0022—Balloons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00273—Anchoring means for temporary attachment of a device to tissue
- A61B2018/00279—Anchoring means for temporary attachment of a device to tissue deployable
- A61B2018/00285—Balloons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00482—Digestive system
- A61B2018/00488—Esophagus
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Otolaryngology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Electrotherapy Devices (AREA)
Abstract
The invention relates to the field of medical equipment, in particular to an electrode device for inactivating tumor cells in an esophageal wall and a using method thereof, wherein the electrode device comprises a workbench and a pushing pipe, an annular electrode is matched in the pushing pipe, and a lead of the annular electrode penetrates out of the upper part of the pushing pipe and is connected with a power distribution controller on the workbench; the invention aims to provide an electrode device for inactivating tumor cells in an esophageal wall and a using method thereof.
Description
Technical Field
The invention relates to the field of medical equipment, in particular to an electrode device for inactivating tumor cells in an esophageal wall and a using method thereof.
Background
Irreversible electroporation (IRE) is a new soft tissue ablation technique that uses ultra-short high voltage direct current (up to 3 kv) to create multiple nano-scale micropores in the cell membrane of cells within the ablated tissue, irreversibly disrupting the intracellular equilibrium, inducing apoptosis and ultimately death.
The irreversible electroporation device mainly comprises a power distribution controller consisting of a high-voltage pulse power supply and an oscilloscope, and electrodes.
The electrode is used for acting direct current high voltage on tissue cells, the electrode widely used at present is a needle electrode, the electrode needle is inserted into the tissue, and a high voltage electric field, namely an ablation area, is formed around the electrode needle, so that the tissue cells in a specific area are inactivated.
Disclosure of Invention
The invention aims to provide an electrode device for inactivating tumor cells in an esophageal wall and a using method thereof.
In order to achieve the above purpose, the invention adopts the technical scheme that: the utility model provides an electrode assembly for tumour cell deactivation in esophagus wall, it includes workstation and propelling movement pipe, the propelling movement intraductal cooperation have a ring electrode, the wire of ring electrode wear out the upper portion of propelling movement pipe and be connected with the distribution controller on the workstation.
Furthermore, an insulating heavy block is arranged in the annular electrode, and the upper part of the heavy block is connected with a pull tube penetrating out of the upper part of the push tube.
Further, ring electrode (10) in be provided with and strut gasbag (8), pouring weight (9) set up in strutting gasbag (8), the trombone slide for with strut gas tube (5) of gasbag (8) intercommunication, gas tube (5) and workstation (1) on air pump (3) the intercommunication that sets up, wire (6) and gas tube (5) tie up through clamp (7) and be in the same place.
Further, the position that gas tube (5) upper portion surpassed propelling movement pipe (4) has linked firmly propelling movement screens rigid coupling seat (14), the upper portion of propelling movement pipe (4) cup jointed middle part open-ended propelling movement screens seat (11), the upper portion of propelling movement screens seat (11) and the lower part of propelling movement screens rigid coupling seat (14) be provided with position matching's propelling movement screens cover (12), and the plug bush has propelling movement screens pole (13) between propelling movement screens cover (12) from top to bottom.
The other technical scheme of the invention is as follows: a method of using an electrode assembly for inactivation of tumor cells in an esophageal wall, comprising the steps of:
①, preparing the device, and inserting a push clamping rod between the upper and lower push clamping sleeves at the beginning;
②, pushing the delivery tube prepared in step ① from the oral cavity to the tumor part of the esophageal wall along the esophageal tube;
③ lifting the pushing clamping fixed seat upwards, then unloading the pushing clamping rod, then making the pushing clamping fixed seat descend under the gravity action of the weight, simultaneously lifting the pushing tube upwards for a certain height and keeping stable, and further making the ring electrode separate from the esophageal tube and match with the tumor part;
④, inflating the opening air bag through the air pump to make the ring electrode generate certain deformation, and further make the ring electrode touch the tumor part of the esophagus wall;
⑤, generating high voltage direct current by the power distribution controller to form a strong electric field around the ring electrode, thereby completing the inactivation of the tumor part of the esophageal wall.
The invention has the beneficial effects that:
1. the annular electrode is used as a working part, the push pipe is used as a feeding medium, and the tumor cells in the wall of the peripheral esophagus can be inactivated by an electric field generated by direct-current high voltage in an equipment using mode with characteristics.
2. The design of the insulating weight can not only ensure that the annular electrode is pushed to the inner wall of the esophagus along with the pushing pipe, but also generate relative displacement with the pushing pipe, so that the annular electrode directly acts with the tumor part.
3. The design of the air bag is opened, so that the annular electrode can deform to a certain degree, the annular electrode can directly contact with tumor tissues in the esophageal wall, and the inactivation treatment effect is improved.
4. The structural design of propelling movement screens cover and propelling movement screens pole can ensure to make annular electrode can with the propelling movement pipe synchronous propelling movement in the propelling movement, has ensured the efficiency of propelling movement, does not influence the subsequent relative motion of the two simultaneously.
Drawings
Fig. 1 is a schematic structural diagram of an electrode device for inactivating tumor cells in an esophageal wall.
Fig. 2 is a partially enlarged view of a in fig. 1.
Fig. 3 is a partially enlarged view of B in fig. 1.
The text labels shown in the figures are represented as: 1. a work table; 2. a power distribution controller; 3. an air pump; 4. pushing the pipe; 5. an inflation tube; 6. a wire; 7. clamping a hoop; 8. the air bag is opened; 9. a weight block; 10. a ring electrode; 11. pushing the clamping seat; 12. pushing the clamping sleeve; 13. pushing the clamping rod; 14. the propelling movement screens rigid coupling seat.
Detailed Description
The following detailed description of the present invention is given for the purpose of better understanding technical solutions of the present invention by those skilled in the art, and the present description is only exemplary and explanatory and should not be construed as limiting the scope of the present invention in any way.
As shown in fig. 1 to 3, the specific structure of the present invention is: the utility model provides an electrode assembly for inactivation of tumour cell in esophagus wall, it includes workstation 1 and propelling movement pipe 4, propelling movement pipe 4 in the cooperation have annular electrode 10, annular electrode 10's wire 6 wear out the upper portion of propelling movement pipe 4 and be connected with distribution controller 2 on the workstation 1.
Preferably, an insulating weight 9 is arranged in the ring electrode 10, and a pull pipe penetrating out of the upper part of the pushing pipe 4 is connected to the upper part of the weight 9.
Preferably, ring electrode 10 in be provided with and strut gasbag 8, pouring weight 9 set up in strutting gasbag 8, the trombone slide for with strut gas tube 5 that gasbag 8 communicates, gas tube 5 and the workstation 1 on the air pump 3 intercommunication that sets up, wire 6 and gas tube 5 tie up together through clamp 7.
Preferably, the position that the inflation tube 5 upper portion surpassed propelling movement pipe 4 has linked firmly propelling movement screens rigid coupling seat 14, the upper portion of propelling movement pipe 4 cup joint middle part open-ended propelling movement screens seat 11, the upper portion of propelling movement screens seat 11 and the lower part of propelling movement screens rigid coupling seat 14 be provided with position matching's propelling movement screens cover 12, and plug bush has propelling movement screens pole 13 between the propelling movement screens cover 12 from top to bottom.
A method of using an electrode device for inactivation of tumor cells in an esophageal wall, comprising the steps of:
①, preparing the device, and inserting a push clamping rod between the upper and lower push clamping sleeves at the beginning;
②, pushing the delivery tube prepared in step ① from the oral cavity to the tumor part of the esophageal wall along the esophageal tube;
③ lifting the pushing clamping fixed seat upwards, then unloading the pushing clamping rod, then making the pushing clamping fixed seat descend under the gravity action of the weight, simultaneously lifting the pushing tube upwards for a certain height and keeping stable, and further making the ring electrode separate from the esophageal tube and match with the tumor part;
④, inflating the opening air bag through the air pump to make the ring electrode generate certain deformation, and further make the ring electrode touch the tumor part of the esophagus wall;
⑤, generating high voltage direct current by the power distribution controller to form a strong electric field around the ring electrode, thereby completing the inactivation of the tumor part of the esophageal wall.
It should be noted that, in this document, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
The principles and embodiments of the present invention are explained herein using specific examples, which are presented only to assist in understanding the method and its core concepts of the present invention. The foregoing is only a preferred embodiment of the present invention, and it should be noted that there are objectively infinite specific structures due to the limited character expressions, and it will be apparent to those skilled in the art that a plurality of modifications, decorations or changes may be made without departing from the principle of the present invention, and the technical features described above may be combined in a suitable manner; such modifications, variations, combinations, or adaptations of the invention using its spirit and scope, as defined by the claims, may be directed to other uses and embodiments.
Claims (1)
1. The electrode device for inactivating tumor cells in an esophageal wall is characterized by comprising a workbench (1) and a pushing tube (4), wherein an annular electrode (10) is matched in the pushing tube (4), a lead (6) of the annular electrode (10) penetrates out of the upper part of the pushing tube (4) and is connected with a power distribution controller (2) on the workbench (1), an insulating heavy block (9) is arranged in the annular electrode (10), the upper part of the heavy block (9) is connected with a pull tube penetrating out of the upper part of the pushing tube (4), a propping air bag (8) is arranged in the annular electrode (10), the heavy block (9) is arranged in the propping air bag (8), the pull tube is an inflating tube (5) communicated with the propping air bag (8), the inflating tube (5) is communicated with an air pump (3) arranged on the workbench (1), wire (6) and gas tube (5) tie up together through clamp (7), gas tube (5) upper portion surpass the position of propelling movement pipe (4) and linked firmly propelling movement screens rigid coupling seat (14), the upper portion of propelling movement pipe (4) cup joint middle part open-ended propelling movement screens seat (11), the upper portion of propelling movement screens seat (11) and the lower part of propelling movement screens rigid coupling seat (14) be provided with propelling movement screens cover (12) that the position matches, and plug bush has propelling movement screens pole (13) between upper and lower propelling movement screens cover (12).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201711420775.4A CN107928782B (en) | 2017-12-25 | 2017-12-25 | Electrode device for inactivating tumor cells in esophageal wall and using method thereof |
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CN201711420775.4A CN107928782B (en) | 2017-12-25 | 2017-12-25 | Electrode device for inactivating tumor cells in esophageal wall and using method thereof |
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CN107928782A CN107928782A (en) | 2018-04-20 |
CN107928782B true CN107928782B (en) | 2020-06-09 |
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CN201711420775.4A Expired - Fee Related CN107928782B (en) | 2017-12-25 | 2017-12-25 | Electrode device for inactivating tumor cells in esophageal wall and using method thereof |
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CN115895877B (en) * | 2022-11-30 | 2024-03-12 | 重庆大学 | Microfluidic chip detection system for reverse killing |
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CN2176804Y (en) * | 1993-09-28 | 1994-09-14 | 王德 | Esophagus cardiac-pacemaking vibration-eliminating electrode device |
AU2012298709B2 (en) * | 2011-08-25 | 2015-04-16 | Covidien Lp | Systems, devices, and methods for treatment of luminal tissue |
WO2014022379A1 (en) * | 2012-07-30 | 2014-02-06 | Northwestern University | Radiofrequency probe for circumferential ablation of a hollow cavity |
CN107920855B (en) * | 2015-08-03 | 2022-05-27 | 波士顿科学医学有限公司 | System and method for mapping and ablation in the bladder |
CN206548600U (en) * | 2016-12-02 | 2017-10-13 | 申小青 | A kind of petal-shaped multi-pole rf ablating electrode pin with air bag |
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Granted publication date: 20200609 Termination date: 20201225 |