CN107928717B - Magnetic composite device for establishing digestive tract passage - Google Patents

Magnetic composite device for establishing digestive tract passage Download PDF

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Publication number
CN107928717B
CN107928717B CN201711219031.6A CN201711219031A CN107928717B CN 107928717 B CN107928717 B CN 107928717B CN 201711219031 A CN201711219031 A CN 201711219031A CN 107928717 B CN107928717 B CN 107928717B
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magnet
arrow
digestive tract
shaped
composite device
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CN107928717A (en
Inventor
乔玮
吕毅
李涤尘
吴荣谦
马锋
严小鹏
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Chonghao Technology Co ltd
Saide Ou Technology Shenzhen Co ltd
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Chonghao Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743Type of operation; Specification of treatment sites
    • A61B2017/00818Treatment of the gastro-intestinal system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831Material properties
    • A61B2017/00867Material properties shape memory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831Material properties
    • A61B2017/00876Material properties magnetic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831Material properties
    • A61B2017/00902Material properties transparent or translucent
    • A61B2017/00915Material properties transparent or translucent for radioactive radiation
    • A61B2017/0092Material properties transparent or translucent for radioactive radiation for X-rays

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Prostheses (AREA)

Abstract

A magnetic composite device for establishing digestive tract passage comprises a main magnet, a developing line, a positioning body, a sub-magnet, a central magnet, an adhesive tape, an arrow-shaped magnet and the like. The mother magnet is connected with the positioning body through a development line; the central magnet is connected with the arrow-shaped magnet through an adhesive tape; a bracket can be arranged in the bracket groove outside the arrow-shaped magnet. The invention establishes or dredges the digestive tract passage by using the squeezing force generated by the magnet alignment attraction in an approximate noninvasive manner of magnetic swallowing, and cuts the squeezed tissue of the anastomotic stoma by using the relative motion generated by the magnet attraction so as to promote the formation of the anastomotic stoma; simultaneously, the stent can be carried into the anastomotic stoma to realize permanent smoothness of the digestive tract passage.

Description

Magnetic composite device for establishing digestive tract passage
Technical Field
The invention belongs to the technical field of medical appliances, and particularly relates to a magnetic composite device for establishing a digestive tract passage.
Background
At present, the reconstruction of the digestive tract is realized through invasive approaches such as surgical operation, intervention or endoscopic operation, and the like, so that a patient or an operator is required to have considerable clinical experience accumulation, and meanwhile, the patient is subjected to anesthesia, operation and postoperative complications risks and the like, and the digestive tract cannot be reconstructed for the patient with operation or anesthesia contraindications, so that the treatment of the patient is influenced. There is no device for reconstructing the digestive tract in an approximately noninvasive manner.
Disclosure of Invention
In order to overcome the disadvantages of the prior art, the present invention aims to provide a magnetic composite device for digestive tract passage establishment, which can realize and promote the digestive tract passage establishment or dredging by utilizing the squeezing and relative movement generated by the mutual attraction of magnets, and can complete stent implantation, wherein the device can effectively and permanently reconstruct or dredge the digestive tract, avoid surgical operation, and has simple and convenient operation.
In order to achieve the above purpose, the technical scheme adopted by the invention is as follows:
a magnetic composite device for digestive tract pathway establishment, comprising:
the parent magnet 1 is a cylinder and can pass through the narrow section (9) of the digestive tract;
the positioning body 3 is an object with the volume larger than that of the digestive tract stenosis 9;
the developing line 2 is a flexible line body, is wound on the positioning body 3, is connected with the mother magnet 1 and the positioning body 3, and controls the position of the mother magnet 1 according to the length of the developing line 2;
the sub-magnet 4 is a cylinder and is attracted with the main magnet 1 under the guidance of an external magnetic field to generate a squeezing force on tissues so as to form an anastomotic stoma;
the central magnet 5 is a cylinder, and the diameter and the material of the central magnet are the same as those of the main magnet 1 and the sub magnets 4;
the arrow-shaped magnet 7 is of an arrow-shaped structure which is uniform from top to bottom, one end of the arrow-shaped magnet is wedge-shaped and protrudes outwards, the other end of the arrow-shaped magnet is of a groove structure, the adhesive tape 6 is in a strip shape, the center magnet 5 is arranged in the arrow-shaped magnet 7 and is connected through the adhesive tape 6, and the bottom of the center magnet 5 is flush with the wedge-shaped end of the arrow-shaped magnet 7 and has opposite polarity; under the guidance of an external magnetic field, the central magnet 5 and the sub-magnets 4 attract each other, and the arrow-shaped magnet 7 cuts the pressed tissues under the action of magnetic force at the moment of attraction, so that the establishment or dredging of a lumen passage is realized.
The main magnet 1, the sub-magnet 4, the central magnet 5 and the arrow-shaped magnet 7 are made of magnetic materials, the sizes and the design of the protective layers can be different according to the application positions, and the surface layer can be provided with the protective layer made of corrosion-resistant nontoxic materials, such as a titanium nitride plating layer, a nickel plating layer, an iron shell and the like. The developing line 2 is made of a soft material which can be developed under X-rays, the positioning body 3 is made of degradable materials such as sucrose, starch, flour or PLGA, and the adhesive tape 6 is made of nontoxic biological glue.
The mutual attraction among the main magnet 1, the sub magnet 4 and the central magnet 5 is completed by external magnetic field guidance and is carried out in an X-ray perspective state.
The arrow-shaped magnet 7 can carry the support 8, the support 8 is attached to the periphery of the outer wall of the arrow-shaped magnet 7, the arrow-shaped magnet 7 cuts the pressed tissue, the support 8 is carried into the anastomotic stoma, and the support 8 is deformed and fixed and stays at the anastomotic stoma.
The support 8 is in a soft and flexible state capable of being deformed at random at 0-30 ℃ and is restored to a rigid state at 35 ℃ or above.
The support 8 is a nickel-titanium shape memory alloy support or other metal supports with constraint lines.
The support 8 may be hollow dumbbell-shaped or tubular in a rigid state according to the location of the action.
The force generated by the attraction of the central magnet 5 and the sub-magnets 4 and used for enabling the arrow-shaped magnet 7 to relatively displace is larger than the bonding force of the adhesive tape 6.
The central magnet 5, the adhesive tape 6 and the arrow-shaped magnet 7 are integrated during processing.
Compared with the prior art, the invention establishes the digestive tract passage by using the squeezing force generated by the magnet alignment attraction in an approximate noninvasive manner of magnetic swallowing, and cuts the squeezed tissue of the anastomotic stoma by using the relative motion generated by the magnet attraction so as to promote the formation of the anastomotic stoma; simultaneously, the stent can be carried into the anastomotic stoma to realize permanent smoothness of the digestive tract passage.
Drawings
FIG. 1 is a schematic diagram showing the state of a parent magnet, a developing line and a positioning body before use in a magnetic composite device for establishing a digestive tract passage according to the present invention.
Fig. 2 is a schematic diagram showing the state of the parent magnet, the developing line and the positioning body after entering the digestive tract in the magnetic composite device for establishing the digestive tract passage according to the present invention.
Fig. 3 is a schematic view showing a state of a neutron magnet in the magnetic composite apparatus for constructing a digestive tract passage according to the present invention after entering the digestive tract.
Fig. 4 is a schematic view (longitudinal cross-sectional view) before use of a center magnet, an adhesive tape, and an arrow-shaped magnet carrying a stent in the magnetic composite device for digestive tract pathway establishment of the present invention.
Fig. 5 is a schematic view (cross-sectional view) before use of the center magnet, adhesive tape, and arrow-shaped magnet in the magnetic composite device for digestive tract pathway establishment of the present invention.
Fig. 6 is a schematic view of the magnetic composite device for establishing the digestive tract passage according to the present invention after the central magnet, the adhesive tape and the arrow-shaped magnet enter the digestive tract to attract the sub-magnets.
Fig. 7 is a schematic view showing a state of the magnetic composite apparatus for digestive tract path establishment after the digestive tract path establishment according to the present invention is established.
Detailed Description
Embodiments of the present invention will be described in detail below with reference to the accompanying drawings and examples.
As shown in fig. 1, the magnetic composite device for establishing the digestive tract passage mainly comprises a main magnet 1, a developing line 2, a positioning body 3, a sub-magnet 4, a central magnet 5, an adhesive tape 6, an arrow-shaped magnet 7 and the like, wherein the central magnet 5, the adhesive tape 6 and the arrow-shaped magnet 7 are integrated during processing.
The main magnet 1, the sub magnet 4 and the central magnet 5 are all cylinders, have the same diameter and the same material, the positioning body 3 is positioned at the near end of the main magnet 1 and is used for positioning, the developing line 2 is a flexible line body, is wound on the positioning body 3 and is connected with the main magnet 1 and the positioning body 3, and the position of the main magnet 1 can be controlled according to the length of the developing line 2; the sub-magnet 4 attracts the main magnet 1 under the guidance of the external magnetic field, and generates a squeezing force on the tissue to form an anastomotic stoma. The arrow-shaped magnet 7 is of an arrow-shaped structure which is uniform from top to bottom, one end of the arrow-shaped magnet is wedge-shaped and protrudes outwards, the other end of the arrow-shaped magnet is of a groove structure, the adhesive tape 6 is in a strip shape, the center magnet 5 is placed into the arrow-shaped magnet 7 and is connected through the adhesive tape 6, the bottom of the center magnet 5 is flush with the wedge-shaped end of the arrow-shaped magnet 7 and opposite in polarity, and the force which is generated after the center magnet 5 and the sub magnet 4 are attracted to enable the arrow-shaped magnet 7 to generate relative displacement is larger than the adhesive force of the adhesive tape 6.
The main magnet 1, the sub-magnet 4, the central magnet 5 and the arrow-shaped magnet 7 are made of magnetic materials, the sizes and the design of the protective layers can be different according to the application positions, and the surface layer can be provided with the protective layer made of corrosion-resistant nontoxic materials, such as a titanium nitride plating layer, a nickel plating layer, an iron shell and the like. The development line 2 is made of a soft X-ray developable material, the positioning body 3 is made of degradable materials such as sucrose, starch, flour or PLGA, and the adhesive tape 6 is made of nontoxic biological glue.
The mutual attraction among the main magnet 1, the sub-magnet 4 and the central magnet 5 is completed by the guidance of an external magnetic field and is performed in an X-ray perspective state.
In order to realize stent placement, a stent 8 can be attached around the arrow-shaped magnet 7, the stent 8 is in a soft and flexible state which can be deformed at will at 0-30 ℃, and is restored to a final rigid state at 35 ℃ or above, and can be in a hollow dumbbell shape or a tubular shape and the like according to different action positions. The arrow-shaped magnet 7 cuts the pressed tissue and carries the bracket 8 into the anastomotic stoma, and the bracket 8 deforms, is fixed and stays at the anastomotic stoma.
The working principle of the invention is as follows:
the magnetic composite device established by the digestive tract passage is swallowed by stages through the oral cavity, the magnetic device carrying the stent 8 is soaked in sterile physiological saline at 0 ℃ before being used, and the nickel-titanium shape memory alloy stent 8 is in a flexible state capable of being deformed at will, so that the magnetic composite device can conveniently enter a body and be placed into an anastomotic orifice. The mother magnet 1 is swallowed together with the development line 2 and the positioning body 3, under the peristalsis of the stomach 10, the duodenum 11 and the jejunum 12 and the pushing of the digestive tract content 13, the mother magnet 1 drives the development line 2 to move towards the distal end of the jejunum 12 after passing through the digestive tract narrow section 9, the positioning body 3 is blocked at the digestive tract narrow section 9, the position of the mother magnet 1 is controlled by the length of the development line 2, after the position of the mother magnet 1 is fixed, the child magnet 4 is swallowed, the child magnet is attracted with the mother magnet 1 under the guidance of an external magnetic field, and a squeezing force is generated on tissues, so that the pressed tissues gradually ischemia and necrosis are generated, and the surrounding uncompressed tissues are proliferated and repaired under the action of inflammation to form an anastomotic orifice; before the tissue of the anastomotic stoma falls off, the magnetic device carrying the bracket 8 is swallowed, the central magnet 5 and the sub-magnet 4 are attracted under the guidance of an external magnetic field, the arrow-shaped magnet 7 is triggered under the action of magnetic force at the attraction moment, the pressed tissue is cut, the bracket 8 is carried into the anastomotic stoma, hot water at the temperature of 35-37 ℃ is drunk, the bracket is gradually deformed, finally the shape is fixed, and the bracket stays at the anastomotic stoma, so that the establishment or dredging of a lumen passage is realized. The positioning body 3 and the adhesive tape 6 are gradually degraded. The rest magnetic devices, including the main magnet 1, the development line 2, the sub-magnet 4, the central magnet 5 and the arrow-shaped magnet 7, are discharged into the distal intestinal tract and discharged out of the body along with the feces.

Claims (10)

1. A magnetic composite device for digestive tract pathway establishment, comprising:
a parent magnet (1) which is a cylinder and can pass through a narrow section (9) of the digestive tract;
the positioning body (3) is an object with the volume larger than the narrow section (9) of the digestive tract;
the developing line (2) is a flexible line body, is wound on the positioning body (3), is connected with the mother magnet (1) and the positioning body (3), and controls the position of the mother magnet (1) according to the length of the developing line (2);
the sub-magnet (4) is a cylinder and is attracted with the main magnet (1) under the guidance of an external magnetic field to generate a squeezing force on tissues so as to form an anastomotic stoma;
the central magnet (5) is a cylinder, and the diameter and the material of the central magnet are the same as those of the main magnet (1) and the sub-magnets (4);
the arrow-shaped magnet (7) is of an arrow-shaped structure which is uniform from top to bottom, one end of the arrow-shaped magnet is wedge-shaped and protrudes outwards, the other end of the arrow-shaped magnet is of a groove structure, the adhesive tape (6) is in a strip shape, the arrow-shaped magnet (7) is placed in the central magnet (5), the arrow-shaped magnet is connected through the adhesive tape (6), and the bottom of the central magnet (5) is flush with the wedge-shaped end of the arrow-shaped magnet (7) and has opposite polarity; under the guidance of an external magnetic field, the central magnet (5) and the sub-magnets (4) attract each other, and the arrow-shaped magnet (7) cuts the pressed tissues under the action of magnetic force at the moment of attraction, so that the establishment or dredging of a lumen passage is realized.
2. The magnetic composite device for digestive tract pathway establishment according to claim 1, wherein the parent magnet (1), the child magnet (4), the center magnet (5), the arrow-shaped magnet (7) are made of magnetic materials, the surface layer is provided with a protective layer made of corrosion-resistant nontoxic materials, the developing line (2) is made of soft X-ray developable materials, the positioning body (3) is made of degradable materials, and the adhesive tape (6) is made of nontoxic biological glue.
3. The magnetic composite device for digestive tract pathway establishment according to claim 2, wherein the protective layer is a titanium nitride plating layer or a nickel plating layer or an iron shell, and the degradable material is sucrose, starch, flour or PLGA.
4. The magnetic composite device for digestive tract passage establishment according to claim 1, wherein the mutual attraction between the main magnet (1), the sub-magnet (4) and the central magnet (5) is accomplished by external magnetic field guidance and is performed under an X-ray perspective state.
5. The magnetic composite device for digestive tract pathway establishment according to claim 1, wherein the arrow-shaped magnet (7) carries a bracket (8), the bracket (8) is attached around the outer wall of the arrow-shaped magnet (7), the arrow-shaped magnet (7) carries the bracket (8) into the anastomotic stoma while cutting the pressed tissue, and the bracket (8) is finally deformed, fixed and stays at the anastomotic stoma.
6. A magnetic composite device for the creation of a digestive tract pathway according to claim 5, characterized in that said stent (8) is in a soft, arbitrarily deformable, flexible state at 0-30 ℃ and returns to a rigid state above 35 ℃.
7. The magnetic composite device for digestive tract pathway establishment according to claim 5, characterized in that the stent (8) is a nitinol stent or a metallic stent with constraining wires.
8. The magnetic composite device for digestive tract passage establishment according to claim 5, wherein the stent (8) is hollow dumbbell-shaped or tubular in a rigid state according to the site of action.
9. The magnetic composite device for digestive tract passage establishment according to claim 1, wherein the force generated by the attraction of the central magnet (5) and the sub-magnets (4) to relatively displace the arrow-shaped magnet (7) is greater than the adhesive force of the adhesive tape (6).
10. The magnetic composite device for digestive tract pathway establishment according to claim 1, wherein the central magnet (5), the adhesive tape (6) and the arrow-shaped magnet (7) are integrated at the time of processing.
CN201711219031.6A 2017-11-28 2017-11-28 Magnetic composite device for establishing digestive tract passage Active CN107928717B (en)

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CN107928717B true CN107928717B (en) 2023-11-24

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Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110404153B (en) * 2018-04-27 2021-10-26 西安交通大学医学院第一附属医院 Magnet and wheat-mango bionic dual-drive reverse intestinal flora transplanting device
CN112704536B (en) * 2021-01-07 2024-05-31 西安交通大学医学院第一附属医院 Magnetic anastomosis device for tissue clamping under digestive endoscope
CN113040849B (en) * 2021-05-06 2024-09-03 西安交通大学医学院第一附属医院 Radial magnetizing anastomat for noninvasive digestive tract reconstruction

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WO2008061024A2 (en) * 2006-11-10 2008-05-22 Wilson-Cook Medical, Inc. Ring magnets for surgical procedures
WO2008106279A1 (en) * 2007-02-28 2008-09-04 Wilson-Cook Medical, Inc. Intestinal bypass using magnets
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CN102631225A (en) * 2012-03-27 2012-08-15 西安交通大学 Dredging device for narrow biliary tract by means of magnetic compression
CN103519858A (en) * 2013-08-27 2014-01-22 中国人民解放军第四军医大学唐都医院 Magnetic force meshing device applicable to field operation surgery digestive tract reconstruction
CN103654903A (en) * 2013-11-27 2014-03-26 西安交通大学 Magnetic biodegradable device for human digestive tract anastomosis
CN208988973U (en) * 2017-11-28 2019-06-18 西安交通大学医学院第一附属医院 A kind of magnetic set composite for alimentary canal path setting

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008061024A2 (en) * 2006-11-10 2008-05-22 Wilson-Cook Medical, Inc. Ring magnets for surgical procedures
WO2008106279A1 (en) * 2007-02-28 2008-09-04 Wilson-Cook Medical, Inc. Intestinal bypass using magnets
WO2011008988A1 (en) * 2009-07-15 2011-01-20 Medical And Surgical Review, P.C. Incisionless gastric bypass method and devices
CN102631225A (en) * 2012-03-27 2012-08-15 西安交通大学 Dredging device for narrow biliary tract by means of magnetic compression
CN103519858A (en) * 2013-08-27 2014-01-22 中国人民解放军第四军医大学唐都医院 Magnetic force meshing device applicable to field operation surgery digestive tract reconstruction
CN103654903A (en) * 2013-11-27 2014-03-26 西安交通大学 Magnetic biodegradable device for human digestive tract anastomosis
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