CN108938163A - Stomach air deflector and its method for releasing - Google Patents

Stomach air deflector and its method for releasing Download PDF

Info

Publication number
CN108938163A
CN108938163A CN201810336514.2A CN201810336514A CN108938163A CN 108938163 A CN108938163 A CN 108938163A CN 201810336514 A CN201810336514 A CN 201810336514A CN 108938163 A CN108938163 A CN 108938163A
Authority
CN
China
Prior art keywords
bracket
stomach
opening
lower bracket
upper bracket
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201810336514.2A
Other languages
Chinese (zh)
Other versions
CN108938163B (en
Inventor
左玉星
鲁艳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hangzhou Sugar Medical Technology Co Ltd
Original Assignee
Hangzhou Sugar Medical Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hangzhou Sugar Medical Technology Co Ltd filed Critical Hangzhou Sugar Medical Technology Co Ltd
Priority to CN201810336514.2A priority Critical patent/CN108938163B/en
Priority to EP18914681.4A priority patent/EP3777784B1/en
Priority to ES18914681T priority patent/ES2934842T3/en
Priority to US16/981,322 priority patent/US11517461B2/en
Priority to PCT/CN2018/111746 priority patent/WO2019196380A1/en
Priority to PL18914681.4T priority patent/PL3777784T3/en
Publication of CN108938163A publication Critical patent/CN108938163A/en
Application granted granted Critical
Publication of CN108938163B publication Critical patent/CN108938163B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/0003Apparatus for the treatment of obesity; Anti-eating devices
    • A61F5/0013Implantable devices or invasive measures
    • A61F5/0036Intragastrical devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/0003Apparatus for the treatment of obesity; Anti-eating devices
    • A61F5/0013Implantable devices or invasive measures
    • A61F5/0076Implantable devices or invasive measures preventing normal digestion, e.g. Bariatric or gastric sleeves

Landscapes

  • Health & Medical Sciences (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Nursing (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

The invention discloses stomach air deflector and its method for releasing, including storage shell, releaser and push component, alimentary stent has shape after the preceding shape of expansion and expansion, which includes upper bracket, lower bracket and connector;After deployment under shape, lower bracket is set to below upper bracket, it is connected between upper bracket and lower bracket by several connectors, 4th opening connection membrane tube of lower bracket, and, upper bracket and lower bracket after expansion can not be by the pyloric ostium of stomach of opening, and connector by pyloric ostium of stomach or can be threaded through at pyloric ostium of stomach.In this way, the alimentary stent, which is divided into two parts, to be fixed, a part is fixed on pyloric ostium of stomach, membrane tube upper end is fixedly positioning in alimentary canal in peristalsis of the digest tract, another part is fixed on duodenal bulb, in alimentary canal anastalsis, avoids lower section from extending membrane tube and easily return in stomach, food is caused not flowed according to design channel.

Description

Stomach air deflector and its method for releasing
Technical field
The present invention relates to the field of medical instrument technology, especially a kind of for treating endocrine system disease (such as diabetes, pancreas islet Dysfunction, obesity etc.) or disease of lower digestive tract (such as inflammation) stomach air deflector and its method for releasing.
Background technique
It is known that diabetes are a kind of diseases being gradually valued by the people in recent years, it is one of rich people's disease, is source It is continuously improved in the living standard of modern civilization society, after people's lives are rich, eat good things, eats smart, overnutrition, activity Amount is reduced, thus the non-infectious epidemic disease generated, specifically, diabetes refer to the metabolic disease characterized by hyperglycemia Disease.It is since defect of insulin secretion or its biological effect are impaired, or both have concurrently caused by.Diabetes can cause various Tissue, especially eye, kidney, heart, blood vessel, the chronic lesion of nerve, dysfunction.Diabetes are usually along with fat and very More complication cause greatly to threaten to people's health.Data are shown, only Chinese, in 20 years old or more adult, glycosuria The disease incidence of disease is 9.7%, population about 1.5 hundred million of falling ill.It is known that it is to keep on a diet that common obesity and diabetes, which improve mode, Increase movement, and assist certain drug therapy, this needs adhering to for a long time for patient, and once stops diet control and movement After easily cause repeatedly and weight gain, the use of long-term drug or insulin also brings heavy financial burden to patient With the inconvenience of life.
Another cure is Gastric bypass, is had very using Gastric bypass for radical cure type-II diabetes and improvement obesity Good effect, in 2001, formal recommendation was metabolized surgical operation (including the operation of stomach turn of tidal stream) conduct to International Diabetes Federation Obesity merges the treatment method of type-II diabetes, however Gastric bypass can cause wound to human body as a kind of surgical operation, because This with many risks such as: death, intestinal obstruction, anastomotic leakage, pulmonary embolism, deep vein thrombosis, injury of portal vein, respiratory system Deng.
Currently, the external structure treatment diabetes also having by being implanted into similar stomach air deflector etc. in the gastrointestinal tract, however, should Structure is complicated for stomach air deflector, it usually needs more bracing wires carry out operation simultaneously just may be implemented its function, needed before operation through Specialized guidance is crossed, not having rich experiences probably will appear operation error, increase sufferer discomfort, operate more tired Difficulty, in addition manufacturing cost is higher, in addition cause it to be difficult home to be promoted and applied on a large scale the problem of technical barrier, A kind of method that patient does not have the treatment diabetes of more sense of discomfort when therefore how to provide implementation, or a kind of structure is provided Simply, easy to operate, the equipment of low-cost treatment diabetes becomes urgent problem to be solved.
At present both at home and abroad there are also being implanted into the product of similar stomach flow-guiding device structure by gastrointestinal tract to treat diabetes, The soft conduit of a piece high molecular material is implanted to duodenum, and the soft conduit generally all passes through a micro metal branch Frame is fixed on duodenal bulb.But the network as made of currently known material is easy hair if not overlay film It gives birth to hyperplasia and is adhered, implantation a period of time is just difficult to take out later, and the bracket of overlay film, then is very easy to fall off.
The product of GI Company Inc. of the U.S. listed at present and domestic patent family design, by support Design at V from word Type, band hangnail are fixed on duodenal bulb in the form of hangnail, and the advantage of the design is to be adapted to most patients, , can be too short to causing Alimentary Tract Perforation because hangnail is too long but there is also certain problem, it is easy to fall off, according to U.S. GI From the point of view of the clinical literature of company, which clinically has 10% or so expulsion rate, and takes out and be implanted into, and unexpected de- It will cause a certain proportion of alimentary canal tearing and bleeding in the case where falling, there are certain application risks.Such as the conduit falls accidentally Enter distal duodenum, jejunum or even colon, be easy to cause intestinal obstruction.Therefore one is needed preferably to design to evade these Risk.
The patent documents such as Publication No. CN103298518, CN105263439, WO2017/052694 disclose in a kind of stomach Device, comprising: cellular structure, the cellular structure include top, bottom and inside and the expansion with the first volume of band Shape after the expansion for the second volume that preceding shape and band are greater than first volume, wherein after the expansion under shape, it is described Cellular structure includes at least one first opening for closing on the top and at least one second opening for closing on the bottom So that food, which passes through at least one described first opening, enters the cellular structure, the inside is passed through, and pass through institute It states at least one second opening and exits the cellular structure;And casing, the casing have elongation main body flexible, have the The proximal end of three openings, distal end and inside pipe casing with the 4th opening, wherein described sleeve pipe is coupled to the porosity knot Structure enters described sleeve pipe so that the food for exiting at least one second opening passes through third opening, passes through the set Inside pipe, and it is open across the described 4th and exits described sleeve pipe.It is in cylindrical body, ellipse after cellular structure (bracket) expansion Body, sphere cube or cuboid occupy quite big volume in stomach and can move freely in stomach, and the diameter of cellular structure is big In the diameter of open pylorus, the casing (membrane tube) of cellular structure bottom passes through pylorus and extends to duodenum.In the stomach Device further comprises being located in the joint of the cellular structure and described sleeve pipe and being attached to the porosity knot Structure or described sleeve pipe or two antimigration components, wherein the antimigration component includes the expansion front construction of compression and opens Constructed after the expansion opened and be designed to close on the pylorus of patient and prevent the cellular structure move to and pass through it is described Pylorus.In above structure, spherical bracket has in stomach, outside pylorus, in pylorus casing (membrane tube) entirely, and the mechanism of action is mainly in stomach It is implanted into the device of the memorial alloy braiding of a netted spherical shape, the spherical bracket overlay film, which occupies one in stomach Fixed volume can form a kind of satiety, and food can store the regular hour in spherical bracket, to reduce food The intake of object plays the role of the metabolic diseases such as treatment obesity and diabetes, and the membrane tube for being used for food drainage is that its is secondary Functional structure.But there are following problems for above-mentioned intragastric device: first is that, the memory alloy material with self-expanding shape has one Fixed mechanical force and weight, volume arrive greatly if capable of occupying intragastric volume, to there is certain compressing in stomach, are implanted in meeting pair in stomach Gastric mucosa has compressing, is very easy to cause digestive tract ulcer;Second is that food residence time in sacculus is long, though stomach can be slowed down Emptying, but it is be easy to cause bacteria breed, cause inflammatory reaction;Third is that the device is in pyloric ostium or duodenal bulb does not have Fixed, lower section extends membrane tube and easily returns in stomach because of alimentary canal anastalsis, and food is caused not flowed according to design channel It is dynamic;Fourth is that the membrane tube volume for being located at pyloric ostium is larger, especially after content food, pylorus foreign body sensation is obvious and be easy to cause pylorus It is closed the not illnesss such as tight, bile regurgitation.
The patent documents such as Publication No. CN102335052, CN104382671, CN204671331, CN205359721 disclose A kind of alimentary stent, main body is by multiple carrier units with certain rigidity and supporting role and the interconnecting pieces being readily bent Part is formed by connecting, and the both ends of connecting component are connected with corresponding carrier unit respectively, and main body is in the right circular cylinder knot being readily bent Structure or the complex structure being readily bent being made of cylindrical body and cone;Carrier unit is whole made of being engraved as metal pipe material Structure or structure made of being woven as silk material, connecting component are woven by the good metal wire rod of flexibility or plastic wire, even Wiring generally with upper and lower bracket plane vertical woven.The bracket is used for gastral narrow or obstruction, plays expansion and branch Narrow effect is supportted, is implanted in alimentary canal generally as a independent product, is not connected to membrane tube, and because its support is strong Degree is high, is unlikely to deform, so being not used to pyloric ostium in stomach, cannot function as the use of stomach air deflector.
Summary of the invention
In order to solve the above technical problems, the object of the present invention is to provide a kind of stomach air deflector and its method for releasing, should The alimentary stent of stomach air deflector consists of two parts, and a part is fixed on pyloric ostium of stomach, and a part is fixed on duodenal bulb Portion.The bracket can provide certain support force, but have certain flexibility, which can guarantee extended segment membrane tube upper section Opening is fixed on duodenal bulb, can be opened and closed with the opening and closing of enteron aisle, will not damage intestinal wall.The membrane tube of extension passes through isolation Food can treat the metabolic diseases such as diabetes, obesity.The bracket applicability is good, and manufacture craft is convenient, at low cost, production is fast Degree is fast, is used for gastral bracket, which can also be connected with implantable conduit.
For above-mentioned the problems of the prior art, the present inventor devises two-part by carefully studying Bracket, and woven using elastic yarn material, it is fixed by pyloric ostium and duodenal bulb both sides, outer film coating prevents Hyperblastosis, can sufficiently solve the problems, such as bracket and membrane tube is easy to fall off or easy hyperplasia, and outer rim is smooth, to tissue It is not damaged.Thereby completing the present invention.
Specifically, present invention employs technical solutions below:
A kind of stomach air deflector, including storage shell (13), releaser and push component, the storage shell (13) is in pipe Shape, the both ends of storage shell (13) are opening, the setting film in folded state to be released in storage shell (13) Manage (7) and alimentary stent as described above, the releaser setting at the distal openings for storing shell (13) and with it is described One end of membrane tube (7) connects, and the releaser by the material that human body intestinal canal is digested and assimilated or dissolved by that can be made;The digestion Road bracket, which has, is unfolded preceding shape and shape after expansion, which includes upper bracket (1), lower bracket (2) and connector (3);After deployment under shape, upper bracket (1) is closing on equipped with the first opening at the top of it and is being equipped with second closing on its bottom Opening, lower bracket (2) be set to upper bracket (1) below, lower bracket (2) close at the top of it be equipped with third be open and closing on it Bottom is equipped with the 4th opening, is connected between upper bracket (1) and lower bracket (2) by several connectors (3), lower bracket (2) 4th opening connection membrane tube (7), also, be unfolded after upper bracket (1) and lower bracket (2) can not pass through the pyloric ostium of stomach of opening (outer diameter of upper bracket (1) and lower bracket (2) after being unfolded is greater than the pyloric ostium of stomach outer diameter opened), connector (3) can lead to It crosses pyloric ostium of stomach or is threaded through at pyloric ostium of stomach.It is fixed in this way, the alimentary stent is divided into two parts, a part of (upper bracket) is solid Due to pyloric ostium of stomach, membrane tube upper end is fixedly positioning in alimentary canal in peristalsis of the digest tract, another part (lower bracket) is fixed In duodenal bulb, in alimentary canal anastalsis, avoids lower section from extending membrane tube and easily return in stomach, cause food not according to setting It is flowed in meter channel.The bracket can provide certain support force, but have certain flexibility, which can guarantee to prolong It stretches a section membrane tube upper section opening and is fixed on duodenal bulb, can be opened and closed with the opening and closing of enteron aisle, intestinal wall will not be damaged.Extend Membrane tube can treat the metabolic diseases such as diabetes, obesity by the way that food is isolated.The bracket applicability is good, manufacture craft convenience, It is at low cost, speed of production is fast, be used for gastral bracket, which can also be connected with implantable conduit.
Preferably, the push component include the inner tube (18) for being successively arranged and capableing of between each other relative motion, Middle pipe (17) and outer tube (16), said inner tube (18) a part are located in the storage shell (13) and connect with the releaser It connects;The proximal openings of shell (13) are stored in one end of the middle pipe (17), and to protrude into the storage shell (13) interior, and it is described in The end of pipe (17) is fixed with the pushing block (14) for being used to push against the membrane tube (7) in storage shell (13);Institute State outer tube (16) be located at it is described storage shell (13) outside and one end be directly or indirectly fixedly connected on storage shell (13) it is close On end opening;Wherein, said inner tube (18) is axially facing operator along it and moves to make the releaser and the containing tube Shell (13) disengages, and inner tube (18) and middle pipe (17) drive the membrane tube (7) to deviate from out of storage shell (13) and be unfolded to discharge.
Preferably, the storage shell (13) is equipped with mark line (25), mark line distance storage shell (13) Distal openings 2 are to 5cm.It is convenient for discharging two brackets up and down respectively inside and outside pyloric ostium in this way.
Preferably, the releaser includes release body case (11) and releaser inner core (12), discharge body case (11) It is arranged at the distal openings of storage shell (13), releaser inner core (12) is connect with inner tube (18), release body case (11) packet Overlay on releaser inner core (12) outside.
Preferably, the connector (3) is connecting line.The connecting line can be threadiness or with the thin of small cross sections product Strip both can guarantee the connection of upper and lower bracket in this way, and not influence flow of food also.In addition, connector is also in other embodiments It can be flexible membrane tube, mesh-structured elastic tube, with flexible or elasticity connecting band or connection sheet etc., but these are connected Even if still the larger stomach pylorus closure that will cause of volume is not tight uncomfortable with patient after part diminution, therefore preferred connecting line.Connecting line It can be wire, such as Nitinol, 304 stainless steels etc., be also possible to the macromolecule material for having good elasticity and fatigue durability Expect silk, such as polyethylene, nylon material.
Preferably, overlay film outside the connecting line.In this way, the contact of isolation connecting line and alimentary canal tissue, reduces friction Damage reduces the probability that gastric ulcer occurs.Connecting line outsourcing overlay film elastic-like material prevents connecting filament excessively sharp keen and damages deep and remote Knocker.Preferably, the film elastic-like material of cladding can be silica gel, one or more materials such as polyurethane.
Preferably, the connector (3) includes more connecting lines, the upper end of more connecting lines is separately connected upper bracket (1), The lower end of more connecting lines is separately connected lower bracket (2).In this way, being vertically connected with upper and lower bracket, stress point using more connecting lines Cloth is more uniform, and fixation is relatively reliable.
Preferably, the position of the corresponding pyloric ostium of stomach of the connector (3) can generate in its natural state, to comply with human body deep and remote The bending on doorway or the elastic deformation of reduced outside diameter.In this way, connector passes through setting treatment, closed substantially when human stomach pylorus is in When conjunction state, the natural extension shape of connector can comply with the structure of human body pyloric ostium and lower part, will not strut pylorus, to deep and remote Door causes to damage, and can extend when up or down under tension, but has shape memory function, in up or down pulling force It can return to the original form when disappearance.
Preferably, the upper bracket (1) is in cone cylinder shape, back taper tubular, straight-tube shape or straw hat shape.In this way, upper bracket Longitudinal sectional view it is trapezoidal in rectangle, class rectangle, class that trapezoidal or two sides are arc, the first opening of upper bracket, the Two openings and exposed edge can be with round corner treatments, to avoid injury tissue.Certainly in other embodiments, upper bracket It can also be in spherical or other shapes.
Preferably, the second opening outer diameter of the upper bracket (1) is greater than the first opening outer diameter.In this way, the spy of upper bracket Point is that lower ending opening is bigger, can be stuck in pyloric ostium and not damage pyloric tissue, and there are two openings, food to lead to for tool up and down It crosses, but does not have the function of storage food.The effect of upper bracket is to be stuck in pyloric ostium to hold lower bracket, holds duodenum indirectly Interior membrane tube avoids membrane tube from moving down during peristalsis of the digest tract and is even discharged.Mouth bracket is greater than pyloric ostium under the upper bracket Diameter, the preferred 20-50mm of diameter.The preferred 20-30mm of back cut diameter.The highly preferred 5-15mm of upper layer bracket 1.
Preferably, the lower bracket is tubular structure.Lower support structure is located inside pyloric ostium, and specifically 12 Duodenum 12 bulb, the major function of the structure are that have a opening for the membrane tube of extension, and food can enter film by this opening Pipe;Second is that membrane tube is ploughed under in stomach from duodenum in order to prevent, is mutually echoed with upper bracket, membrane tube position is fixed;Third is that up and down Bracket limits inside and outside pyloric ostium of stomach respectively, prevent upper bracket from moving freely in stomach, is connected with lower bracket and membrane tube, on Bracket only has a small amount of displacement in pyloric ostium, avoids discomfort.The outer diameter and under shed of the upper opening (third opening) of lower bracket The outer diameter of (the 4th opening) is preferably identical, and such lower bracket is straight, and the longitudinal sectional view of lower bracket is rectangle or circle Angular moment shape can have some rounded corners up and down, primarily to preventing injury tissue.But the upper opening of lower bracket (open by third Mouthful) outer diameter and the outer diameter of under shed (the 4th opening) can also be different, i.e., the side wall of lower bracket can have certain taper or Person's radian, to adapt to duodenal bulb structure and convenient for connection membrane tube.
Preferably, the diameter of the lower bracket is 15~25cm, match with the duodenal bulb diameter of human body, under Support height is 5-20mm.It is preferred that 10mm, this is highly as small as possible under the premise of being able to satisfy above functions, to reach human body most Big comfortable limit.
The lower end of upper bracket and the upper end distance of lower bracket are 20-60mm, are preferably closed according to the different anatomical structure of human body Suitable size, principle are to be greater than the height of pyloric ring, and the lower end of lower bracket will avoid duodenofiberscope.
Upper and lower bracket is reticular structure, can be process by the technique for weaving or cutting, mesh-structured to can be water chestnut Shape, honeycombed, the various shapes such as zigzag.The structure allows bracket in horizontal and vertical Free Compression and expansion, has good Elasticity.Preferably, upper bracket (1) and lower bracket (2) are compiled by elastic yarn (4), elastic yarn (4) outer surface is covered Overlay film is distinguished in the whole outer surface of film or upper bracket (1), lower bracket (2).It can isolate bracket silk material and stomach inner tissue in this way Contact, reduce frictionally damage, reduce gastric ulcer occur probability, prevent hyperblastosis, polymer material film can be silica gel, One or more of medical materials such as TPU, TPE.The braided wires are the elastic yarn for meeting biocompatibility, can be gold Belong to silk, high molecular material silk either degradation material silk.
Lower bracket is fixedly connected by suture, hot pressing, ultrasonic bonding or laser welding with membrane tube.
Preferably, the upper end of connecting line is fixedly connected with the position at the top of upper bracket (1) close to the first opening, connecting line Lower end and lower bracket (2) at the top of be fixedly connected close to the position of third opening.Such preferred embodiment can be to avoid alimentary canal The bottom crimp that bracket bears upper bracket when upper lower pulling force influences to fix, and face is resilient outside upper bracket bottom and pyloric ostium of stomach Connecting line, upper bracket damage alimentary canal tissue can be reduced or avoided in contact support.
Preferably, the upper end of connecting line is fixedly connected with the position at the top of upper bracket (1) close to the first opening, connecting line In the middle part of pile warp upper bracket (1) after establishment mesh, the lower end of connecting line is fixed with the position at the top of lower bracket (2) close to third opening Connection.When preferred embodiment further in this way can bear upper lower pulling force to avoid alimentary stent upper bracket generation spin upside down from And influence to fix, and be resilient face contact support outside upper bracket and pyloric ostium of stomach, alimentary canal tissue damage can be reduced or avoided Wound.
Preferably, the upper bracket (1) and lower bracket (2) are equipped with developing ring (6), can in locating support under X-ray, The preferred platinum of the developing ring, gold or tantalum etc..
Preferably, the upper bracket (1) is equipped with upper bracket exhausting line (8), lower bracket (2) is recycled equipped with lower bracket Line (9).Alimentary stent and membrane tube can be taken out by special recover or endoscope-use nipper in this way.
A kind of method for releasing of stomach air deflector, including stomach air deflector as described above and following step:
1) distal end of shell (13) is stored in storage shell (13) in the membrane tube of folded state and alimentary stent setting Opening is closed by releaser;
2) under the guidance of seal wire, the releaser for storing shell (13) distal end is sent into duodenum, then by releaser Storage shell is released with membrane tube;
3) storage shell is withdrawn again, until mark line reaches pyloric ostium, lower bracket is released from storage shell, lower bracket Stay in duodenal bulb;
4) storage shell is withdrawn again, and upper bracket is released from storage shell, allows upper bracket to stay in outside pyloric ostium, completes to release It puts.
The present invention can be fixed on pyloric ostium, lower branch due to using the upper bracket of above technical scheme, alimentary stent Frame can be fixed on duodenal bulb, it is ensured that the membrane tube can be fixed in duodenum steadily in the long term, and will not be damaged It hurts sb.'s feelings body tissue.And the bracket outer layer has overlay film, can reduce the friction of bracket and tissue, avoids caused by being chronically implanted Hyperblastosis facilitates the taking-up in later period.And the upper bracket for being fixed on pyloric ostium is open at one end in pyloric ostium, and the other end is opened on In stomach, the emptying time of stomach can also be delayed, compared with traditional stomach air deflector or being duodenal sleeve, in treatment glycosuria There is better curative effect in terms of the metabolic diseases such as disease, obesity.The bracket applicability is good, and manufacture craft is convenient, at low cost, production Speed is fast.It is connected with alimentary canal membrane tube.Bracket of the present invention can plant alimentary canal, for treating endocrine system disease, such as glycosuria Disease, islet function disorder, obesity etc. or disease of lower digestive tract, such as inflammation.Compared with prior art, bracket of the invention It can effectively prevent the hyperplasia organized after implantation, and can be fixed on for a long time at pyloric ostium and duodenofiberscope, and will not be to people Body alimentary canal causes to damage.And having structure applicability good, manufacture craft is convenient, at low cost, speed of production is fast, quality is guaranteed And the advantages that easily manufactured, and comfort, compliance are good after implantation, will not damage to tissue.In addition, the branch Frame can also be connected with implantable membrane tube, can reduce after connecting membrane tube to gastral stimulation, and lifting is made to adjust or recycle branch Frame is more conveniently, safely.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of stomach air deflector of the present invention;
Fig. 2 is the enlarged structure schematic diagram of stomach air deflector of the present invention distal end;
Fig. 3 is the deployed configuration side view (single line straw hat type bracket) of alimentary stent embodiment 1 of the present invention;
Fig. 4 is the deployed configuration front view (single line straw hat type bracket) of alimentary stent embodiment 1 of the present invention;
Fig. 5 is the deployed configuration side view (two-wire straw hat type bracket) of alimentary stent embodiment 2 of the present invention;
Fig. 6 is the deployed configuration front view (two-wire straw hat type bracket) of alimentary stent embodiment 2 of the present invention;
Fig. 7 is the deployed configuration side view (three line trapezoid supports) of alimentary stent embodiment 3 of the present invention;
Fig. 8 is the deployed configuration front view (three line trapezoid supports) of alimentary stent embodiment 3 of the present invention;
Fig. 9 is the deployed configuration side view (two-wire inverted trapezoidal bracket) of alimentary stent embodiment 4 of the present invention;
Figure 10 is the deployed configuration side view (two-wire trapezoid support) of alimentary stent embodiment 5 of the present invention;
Figure 11 is the deployed configuration side view (two-wire arc stent) of alimentary stent embodiment 6 of the present invention;
Figure 12 is the deployed configuration schematic diagram of membrane tube of the present invention and alimentary stent;
Figure 13 is membrane tube of the present invention and the schematic diagram that alimentary stent is placed in human body alimentary canal.
Description of symbols: 1- upper bracket;2- lower bracket;3- connecting line;4- elastic yarn;5- bracket overlay film;6- developing ring; 7- membrane tube;8- upper bracket exhausting line;9- lower bracket exhausting line;11- discharges body case;12- releaser inner core;13- stores shell; 14- pushing block;15- nut;16- outer tube;It is managed in 17-;18- inner tube;21- back handle;Handle in 22-;23 limit bulbs;24 remote holders Handle;25 mark lines;101- stomach;102- pyloric ostium;103- duodenal bulb;104- duodenofiberscope;105- duodenum; 106- jejunum.
Specific embodiment
The embodiment of the present invention is described below in detail, examples of the embodiments are shown in the accompanying drawings, wherein from beginning to end Same or similar label indicates same or similar element or element with the same or similar functions.Below with reference to attached The embodiment of figure description is exemplary, it is intended to is used to explain the present invention, and is not considered as limiting the invention.
In the description of the present invention, it is to be understood that, term " center ", " longitudinal direction ", " transverse direction ", " length ", " width ", " thickness ", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom" "inner", " clockwise ", " inverse The orientation or positional relationship of the instructions such as hour hands " is to be based on the orientation or positional relationship shown in the drawings, and is merely for convenience of description originally Invention and simplified description, rather than the device or element of indication or suggestion meaning must have a particular orientation, with specific side Position construction and operation, therefore be not considered as limiting the invention.
In addition, term " first ", " second " are used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance Or implicitly indicate the quantity of indicated technical characteristic.Define " first " as a result, the feature of " second " can be expressed or Implicitly include one or more of the features.In the description of the present invention, unless otherwise indicated, the meaning of " plurality " is two It is a or more than two, unless otherwise restricted clearly.
In the present invention unless specifically defined or limited otherwise, term " installation ", " connected ", " connection ", " fixation " etc. Term shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or be integrally connected;It can be machine Tool connection, is also possible to be electrically connected;It can be directly connected, two members can also be can be indirectly connected through an intermediary Connection inside part.For the ordinary skill in the art, above-mentioned term can be understood in this hair as the case may be Concrete meaning in bright.
In the present invention unless specifically defined or limited otherwise, fisrt feature second feature "upper" or "lower" It may include that the first and second features directly contact, also may include that the first and second features are not direct contacts but pass through it Between other characterisation contact.Moreover, fisrt feature includes the first spy above the second feature " above ", " above " and " above " Sign is right above second feature and oblique upper, or is merely representative of first feature horizontal height higher than second feature.Fisrt feature exists Second feature " under ", " lower section " and " following " include that fisrt feature is directly below and diagonally below the second feature, or is merely representative of First feature horizontal height is less than second feature.
A kind of stomach air deflector as shown in Figure 1 and Figure 2, including storage shell 13, releaser and push component, the receipts Receive shell 13 in a tubular form, the both ends of the storage shell 13 are opening, are arranged in the storage shell 13 to be released in folding The membrane tube 7 and alimentary stent of state, the releaser be arranged in storage shell 13 distal openings at and with the membrane tube 7 One end connection, the releaser by the material that human body intestinal canal is digested and assimilated or dissolved by that can be made;The push component includes It is successively arranged and is capable of between each other inner tube 18, middle pipe 17 and the outer tube 16 of relative motion, 18 a part of said inner tube is located at It is connect in the storage shell 13 and with the releaser;One end of the middle pipe 17 is protruded into through storing the proximal openings of shell 13 In the storage shell 13, and the end of the middle pipe 17 be fixed with it is described for pushing against in the storage shell 13 The pushing block 14 of membrane tube 7;The outer tube 16 is located at outside the storage shell 13 and one end is directly or indirectly fixedly connected on storage In the proximal openings of shell 13;Wherein, said inner tube 18 is axially facing operator along it and moves to make the releaser and institute It states storage shell 13 to disengage, inner tube 18 and middle pipe 17 drive the membrane tube 7 to deviate from out of storage shell 13 and be unfolded to discharge.
The storage shell 13 is equipped with mark line 25, distal openings 2 of the mark line apart from storage shell 13 to 5cm. The releaser includes release body case 11 and releaser inner core 12, and the distal end that storage shell 13 is arranged in release body case 11 is opened At mouthful, releaser inner core 12 is connect with inner tube 18, and release body case 11 is coated on outside releaser inner core 12.
A kind of alimentary stent of stomach air deflector as shown in Fig. 3-11, which, which has, is unfolded preceding shape and exhibition Open rear shape, including upper bracket 1, lower bracket 2 and connector 3;After deployment under shape, upper bracket 1 is equipped with closing at the top of it First is open and is closing on its bottom equipped with the second opening, and lower bracket 2 is set to 1 lower section of upper bracket, and lower bracket 2 is closing on Qi Ding Portion is equipped with third and is open and is closing on its bottom equipped with the 4th opening, is connected between upper bracket 1 and lower bracket 2 by several Part 3 connect, lower bracket 2 the 4th opening connection membrane tube 7, also, be unfolded after upper bracket 1 and lower bracket 2 can not by The pyloric ostium of stomach (outer diameter of upper bracket 1 and lower bracket 2 after being unfolded is greater than the pyloric ostium of stomach outer diameter opened) opened, connector 3 It by pyloric ostium of stomach or can be threaded through at pyloric ostium of stomach.It is fixed in this way, the bracket is divided into two parts, a part of (upper bracket) is solid Due to pyloric ostium of stomach, membrane tube upper end is fixedly positioning in alimentary canal in peristalsis of the digest tract, another part (lower bracket) is fixed In duodenal bulb, in alimentary canal anastalsis, avoids lower section from extending membrane tube and easily return in stomach, cause food not according to setting It is flowed in meter channel.The bracket can provide certain support force, but have certain flexibility, which can guarantee to prolong It stretches a section membrane tube upper section opening and is fixed on duodenal bulb, can be opened and closed with the opening and closing of enteron aisle, intestinal wall will not be damaged.Extend Membrane tube can treat the metabolic diseases such as diabetes, obesity by the way that food is isolated.The bracket applicability is good, manufacture craft convenience, It is at low cost, speed of production is fast, be used for gastral bracket, which can also be connected with implantable conduit.
The connector 3 is connecting line.The connecting line can be threadiness or the fine strip shape with small cross sections product, so both The connection that can guarantee upper and lower bracket, does not influence flow of food also.In addition, connector can also be flexible in other embodiments Membrane tube, mesh-structured elastic tube, connecting band with flexibility or elasticity or connection sheet etc., even if but these connectors diminution Still the larger stomach pylorus closure that will cause of volume is not tight uncomfortable with patient afterwards, therefore preferred connecting line.Connecting line can be metal Silk, such as Nitinol, 304 stainless steels etc. are also possible to the high molecular material silk for having good elasticity and fatigue durability, such as poly- second The materials such as alkene, nylon.
Overlay film outside the connecting line.In this way, the contact of isolation connecting line and alimentary canal tissue, reduces frictionally damage, reduce The probability that gastric ulcer occurs.Connecting line outsourcing overlay film elastic-like material, prevents connecting filament excessively sharp keen and damages pyloric ring.As It is preferred that the film elastic-like material of cladding can be silica gel, one or more materials such as polyurethane.
The connector 3 includes more connecting lines, and the upper end of more connecting lines is separately connected upper bracket 1, more connecting lines Lower end is separately connected lower bracket 2.In this way, being vertically connected with upper and lower bracket using more connecting lines, distribution of force is more uniform, fixed It is relatively reliable.
The position of the corresponding pyloric ostium of stomach of the connector 3 can generate in its natural state the bending for complying with human body pyloric ostium or The elastic deformation of reduced outside diameter.In this way, connector passes through setting treatment, when human stomach pylorus is in basic closed state, even The natural extension shape of fitting can comply with the structure of human body pyloric ostium and lower part, will not strut pylorus, cause to pylorus structure Damage, can extend when up or down under tension, but have shape memory function, when up or down pulling force disappears It can return to the original form.
The upper bracket 1 is in cone cylinder shape, back taper tubular, straight-tube shape or straw hat shape.In this way, the longitudinal cross-section of upper bracket regards Figure is trapezoidal for class rectangle, the class of arc in rectangle, trapezoidal or two sides, and the first of upper bracket is open, second is open and outer Revealing edge can be with round corner treatment, to avoid injury tissue.Certainly in other embodiments, upper bracket can also be in spherical Or other shapes.
Second opening outer diameter of the upper bracket 1 is greater than the first opening outer diameter.In this way, the characteristics of upper bracket is lower ending opening It is bigger, pyloric ostium can be stuck in and do not damage pyloric tissue, there are two opening, food can pass through tool, but not have up and down Store the function of food.The effect of upper bracket is to be stuck in pyloric ostium to hold lower bracket, holds duodenal membrane tube indirectly, keeps away Exempt from membrane tube and moves down even discharge during peristalsis of the digest tract.Mouth bracket is greater than pyloric ostium diameter under the upper bracket, and diameter is excellent Select 20-50mm.The preferred 20-30mm of back cut diameter.The highly preferred 5-15mm of upper layer bracket 1.
The lower bracket is tubular structure.Lower support structure is located inside pyloric ostium, specifically duodenal bulb, The major function of the structure is that have a opening for the membrane tube of extension, and food can enter membrane tube by this opening;Second is that being It prevents membrane tube from ploughing under in stomach from duodenum, is mutually echoed with upper bracket, membrane tube position is fixed;Third is that upper and lower bracket limits respectively Position is inside and outside pyloric ostium of stomach, prevent upper bracket is connected, upper bracket only exists from moving freely in stomach with lower bracket and membrane tube Pyloric ostium has a small amount of displacement, avoids discomfort.The outer diameter and under shed (the 4th opening) of the upper opening (third opening) of lower bracket Outer diameter it is preferably identical, such lower bracket is straight, and the longitudinal sectional view of lower bracket is rectangle or round rectangle, up and down There can be some rounded corners, primarily to preventing injury tissue.But the outer diameter of the upper opening of lower bracket (third opening) and The outer diameter of under shed (the 4th opening) can also be different, i.e., the side wall of lower bracket can have certain taper or radian, with suitable Answer duodenal bulb structure and convenient for connection membrane tube.
The diameter of the lower bracket is 15~25cm, is matched with the duodenal bulb diameter of human body, lower bracket height For 5-20mm.It is preferred that 10mm, this is highly as small as possible under the premise of being able to satisfy above functions, maximum comfortable to reach human body Limit.
The upper end of connecting line is fixedly connected with 1 top of upper bracket close to the position of the first opening, and the lower end of connecting line is under 2 top of bracket is fixedly connected close to the position of third opening.Such preferred embodiment can be born up and down to avoid alimentary stent The bottom crimp of upper bracket influences to fix when pulling force, and face contact support, energy are resilient outside upper bracket bottom and pyloric ostium of stomach Connecting line, upper bracket damage alimentary canal tissue is enough reduced or avoided.
The upper end of connecting line is fixedly connected with 1 top of upper bracket close to the position of the first opening, connecting line pile warp upper bracket 1 After mesh is worked out at middle part, the lower end of connecting line is fixedly connected with 2 top of lower bracket close to the position of third opening.It is further in this way Preferred embodiment when can bear upper lower pulling force to avoid alimentary stent upper bracket generation spin upside down to influence to fix, and It is resilient face contact support outside upper bracket and pyloric ostium of stomach, alimentary canal tissue damage can be reduced or avoided.
The lower end of upper bracket and the upper end distance of lower bracket are 20-60mm, are preferably closed according to the different anatomical structure of human body Suitable size, principle are to be greater than the height of pyloric ring, and the lower end of lower bracket will avoid duodenofiberscope.
Upper and lower bracket is reticular structure, can be process by the technique for weaving or cutting, mesh-structured to can be water chestnut Shape, honeycombed, the various shapes such as zigzag.The structure allows bracket in horizontal and vertical Free Compression and expansion, has good Elasticity.Preferably, upper bracket 1 and lower bracket 2 are compiled by elastic yarn 4, and 4 outer surface overlay film of elastic yarn, Huo Zheshang The whole outer surface difference overlay film of bracket 1, lower bracket 2.It can isolate the contact of bracket silk material with stomach inner tissue in this way, reduction rubs It wears wound, reduces the probability that gastric ulcer occurs, prevent hyperblastosis, polymer material film can be silica gel, and TPU, TPE etc. are medical One or more of material.The braided wires are the elastic yarn for meeting biocompatibility, can be wire, macromolecule material Expect silk either degradation material silk.
Lower bracket and membrane tube pass through hot melt, hot pressing, the one kind such as ultrasonic bonding, high-frequency welding, suture or laser welding Or it a variety of is fixedly connected.
Preferably, the upper end of connecting line is fixedly connected with 1 top of upper bracket close to the position of the first opening, connecting line Lower end is fixedly connected with 2 top of lower bracket close to the position of third opening.Such preferred embodiment can be to avoid alimentary stent The bottom crimp of upper bracket influences to fix when lower pulling force in receiving, and face contact is resilient outside upper bracket bottom and pyloric ostium of stomach Connecting line, upper bracket damage alimentary canal tissue can be reduced or avoided in support.
Preferably, the upper end of connecting line and the top of upper bracket 1 are fixedly connected close to the position of the first opening, connecting line around After working out mesh in the middle part of upper bracket 1, the lower end of connecting line is fixedly connected with 2 top of lower bracket close to the position of third opening. Upper bracket generation spins upside down to shadow when preferred embodiment further in this way can bear upper lower pulling force to avoid alimentary stent It rings and fixes, and be resilient face contact support outside upper bracket and pyloric ostium of stomach, alimentary canal tissue damage can be reduced or avoided.
Stomach air deflector includes conveyer and built-in casing.Conveyer is made of handle and delivery conduit, and built-in casing is by disappearing Change road bracket and membrane tube composition.Built-in casing enters human body by conveyer, and stays in duodenum.In the present invention, digestion Road bracket is made of upper bracket 1 and lower bracket 2, and there is the connection of connecting line 3 in centre.Upper bracket 1 and lower bracket 2 can be by elastic wires Material is worked out or tubular material is cut, and material can be medical implantable material, such as Nitinol, and 316 is stainless Steel, polyurethane, the one or more material such as almag.
The Stent is cut into reticular structure, and network interface can be the various structures such as diamond shape, hexagon, bracket Freely it can be stretched and be compressed horizontal and vertical, and can be with spontaneous recovery at the shape and size of pre-setting.
The upper bracket 1 can be fixed on pyloric ostium, and lower ending opening diameter is greater than the maximum gauge that pyloric ostium opens, shape Shape include but is not limited to be Fig. 3, Fig. 5, the various shape of Fig. 7, Fig. 9, Figure 10 and Figure 11, principle is can be fixed on pyloric ostium Outside, pyloric ostium, but the normal function by not influencing stomach and pylorus are not fallen into, it will not be to digestive tract wall by damaging.Clinical root is factually Border needs can choose different brackets.
Preferably, 1 lower mouthful of bracket of the upper bracket is greater than pyloric ostium diameter, the preferred 20-50mm of diameter.Back cut diameter is excellent Select 20-30mm.The highly preferred 5-15mm of upper layer bracket 1.
The main function of the lower bracket 2 is to be connected with membrane tube, and membrane tube upper end is made to keep opening after bulb is opened Mouth state, it is ensured that chyme can enter in membrane tube, be isolated with digestive tract wall.The shape design of lower bracket 2, which mainly meets, changes The size of duodenal bulb, and be slightly larger than bulb diameter.
Preferably, 2 lower port diameter of lower bracket is greater than pyloric ostium diameter, the preferred 20-30mm of diameter.Back cut diameter is excellent Select 20-30mm.Slightly larger than human body duodenal bulb diameter.The highly preferred 5-15mm of upper layer bracket 2.
The function of the connecting line is that connection upper bracket 1 and lower bracket 2, the quantity of connecting line can be such as Fig. 3 to Fig. 8 Described 1,2,3 or more.Main function is connection upper bracket 1 and lower bracket 2, when lower bracket 2 is with membrane tube 7 Upper bracket can be caught hold of by connecting line 3 by upper layer bracket 1 when moving down, when upper bracket 1 is toward can be with when floating Lower bracket 2 is dragged by connecting line 3.
The connecting line 3 can be formed by meeting the material that human body implantation requires, as preferably can be Nitinol, 316 stainless steels, polyurethane, silica gel, one or more materials such as almag.
Cut or injured to protect pyloric ostium to avoid being connected line 3,3 external sheath biocompatibility of connecting line it is soft Property material, preferably, covering material can be silica gel, polyurethane, the one or more materials such as polyethylene.
The damage of hyperplasia and reduction bracket friction to tissue in order to prevent, the upper bracket 1 and lower bracket 2 are all covered with guarantor Cuticula 5.The protective film must be the material for meeting human body implantation and requiring.Preferably, the material of overlay film can be silica gel, Polyurethane, the one or more material such as polyethylene.
There is a certain distance among the upper bracket 1 and lower bracket 2, preferably, the lower end of upper bracket 1 and lower bracket 2 upper section distance is 20-60mm, and according to human body, different anatomical structures is preferably suitably sized, and principle is to be greater than pyloric ring Height, the lower end of lower bracket 2 will avoid duodenofiberscope 104.
There is developing ring 6 on the upper bracket 1 and lower bracket 2, can clearly be positioned under X-ray, the developing ring can To be the harmless heavy metal material such as platinum, gold, tantalum.
The upper bracket 1 and 2 upper end of lower bracket has exhausting line 8 and exhausting line 9 respectively, and the exhausting line 8 and 9 is distinguished The outmost turns of upper bracket 1 and lower bracket 2 are sutured in, can be taken out bracket simultaneously from internal by special recover or nipper Recycling.When drawing in exhausting line, upper layer bracket 1 and lower floor support 2 bounce back respectively, into scope hyaline cap or specific recycling In device, as endoscope takes out out of human body alimentary canal.The exhausting line 8 and 9 can be PE, nylon, terylene etc. and meet The material of biocompatibility requirement.
A kind of method for releasing of stomach air deflector, including stomach air deflector as described above and following step:
1) distal openings of shell 13 are stored in storage shell 13 in the membrane tube of folded state and alimentary stent setting It is closed by releaser;
2) under the guidance of seal wire, the releaser for storing 13 distal end of shell is sent into duodenum, then by releaser and Membrane tube releases storage shell;
3) storage shell is withdrawn again, until mark line reaches pyloric ostium, lower bracket is released from storage shell, lower bracket Stay in duodenal bulb;
4) storage shell is withdrawn again, and upper bracket is released from storage shell, allows upper bracket to stay in outside pyloric ostium, completes to release It puts.
Before use, membrane tube and alimentary stent are compressed and are accommodated in storage shell 13, distally by release body case 11 It is closed with inner core 12.In use, distal end releaser enters human body duodenum under the guidance of seal wire.By unlocking releaser Afterwards, pipe 17 then in unlocking, handle 22 in promotion, first completes first stage push, releaser and membrane tube 7 is released storage shell 13, then storage shell 13 is withdrawn, until mark line 25 reaches pyloric ostium, lower bracket 2 is released from storage shell 13, completes the Two-stage push, lower bracket 2 stay in duodenal bulb 103, then upper bracket 1 is released from storage shell 13, allow upper bracket 1 Pyloric ostium 102 is stayed in, release is completed.Specifically, will first limit bulb 23 when handle operates by " 0 " shelves and rotate to " 1 " shelves, Pipe 17 in unlock, slowly push in handle 22, until being hampered, power cannot be pushed, the first stage push complete, body case will be discharged 11 and membrane tube 7 release storage shell 13, then withdraw storage shell 13, until mark line 25 reach pyloric ostium, rotary spacing bulb 23 rotate to " 2 " shelves by " 1 " shelves, again pipe 17 in unlock, slowly handle 22 in promotion, and until being hampered, power cannot be pushed, and second Stage push is completed, and lower bracket 2 is released from storage shell 13, lower bracket 2 stays in duodenal bulb 103, rotates again It limits bulb 23 and rotates to " 3 " shelves by " 2 " shelves, pipe 17 in unlock withstands middle handle 22, pulls back front hand grip 24, by upper bracket 1 It is released from storage shell 13, upper bracket 1 is allowed to stay in pyloric ostium 102, complete release.) membrane tube 7 with intestines peristalsis reach jejunum Upper section, 12 automatic dissolving of releaser inner core, release body case 11 and membrane tube 7 disengage automatically at this time, complete release process.Conveyer Human body is withdrawn from from oral cavity, and built-in casing then stays in the body, and plays the role of that food is isolated.
The implantable conduit can play the role of that food is isolated in enteron aisle, change the physiology flow direction of food, implantation After a period of time, the Insulin resistance of patient body is eliminated, and the food stream can also promote patient's body pancreas through mode Element secretion in island reduces Intra-islet Apoptosis and is allowed to rise in value, and islet function restores, and the metabolic diseases such as diabetes, obesity obtain It cures.The stretch modulus of the implantable conduit is 250MP or more, and elongation percentage is greater than 230%, and material softness is planted in vivo Phenomena such as nausea caused by after entering, vomiting abdominal pain, can be substantially reduced.
Implantable conduit according to the present invention can plant alimentary canal, to be used to treat endocrine system disease, such as diabetes, pancreas Island dysfunction, obesity etc. or disease of lower digestive tract, such as inflammation.Compared with prior art, of the present invention implantable Conduit, have structure is simple, structure applicability is good, manufacture craft is convenient, at low cost, speed of production is fast, quality it is guaranteed with And the advantages that easily manufactured, and comfort, compliance are good after implantation, will not damage to tissue.
For compared with the existing technology, upper bracket of the present invention is fixed on pyloric ostium, and lower bracket is fixed on duodenal bulb, And connect membrane tube.Two brackets cannot all be move freely, and can only have small-scale displacement, and specifically upper layer bracket will not enter Inside pylorus, lower floor support will not enter outside pylorus, and there is connecting line in centre, and displacement range does not exceed connecting line model It encloses.Upper and lower bracket junction height is 1-8cm, different according to different human body structure, the result is that upper bracket is made to be located at pylorus Outside, lower bracket is located at duodenal bulb, and the bottom of lower bracket will not arrive duodenofiberscope portion, not influence nipple Normal function.Action principle of the present invention is mainly implanted into a membrane tube in duodenum, and extends to gastral distal end, passes through Food is isolated in membrane tube, to change metabolic mechanism, plays the role of the metabolic diseases such as treatment obesity and diabetes.The effect of bracket Predominantly fixed membrane tube, and membrane tube is strutted, allow food that can enter the membrane tube of implantation.Membrane tube (sleeve) length that the present invention extends It is principal functional structure for 600mm-1600mm.Upper bracket is smaller, will not be small under alimentary stent to causing stress in stomach Upper big structure is easy emptying, and food is not easy to be detained.Pyloric ostium has bracket to fix, and echoes up and down, membrane tube position is not easy to be displaced.
Relative to the patents such as Publication No. CN102335052, CN104382671, CN204671331, CN205359721 text It offers and discloses for a kind of alimentary stent, not only function is different by the present invention, but also structure is also different: in the present invention, on Lower bracket shape is different;Connecting line is arc, needs to comply with the anatomical structure of pyloric ostium;Connecting line is generally two or more with even It connects firm;For the fixation of pyloric ostium, an enteron aisle isolation membrane tube is specifically fixed, product has particular application as treatment glycosuria The metabolic diseases such as disease and obesity.Lower bracket needs to connect one section of soft membrane tube, can just play therapeutic purposes.
In the description of this specification, reference term " one embodiment ", " some embodiments ", " example ", " specifically show The description of example " or " some examples " etc. means specific features, structure, material or spy described in conjunction with this embodiment or example Point is included at least one embodiment or example of the invention.In the present specification, schematic expression of the above terms are not Centainly refer to identical embodiment or example.Moreover, particular features, structures, materials, or characteristics described can be any One or more embodiment or examples in can be combined in any suitable manner.
Although the embodiments of the present invention has been shown and described above, it is to be understood that above-described embodiment is example Property, it is not considered as limiting the invention, those skilled in the art are not departing from the principle of the present invention and objective In the case where can make changes, modifications, alterations, and variations to the above described embodiments within the scope of the invention.It is all of the invention Within spirit and principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.

Claims (10)

1. a kind of stomach air deflector, including storage shell (13), releaser and push component, the storage shell (13) is in pipe Shape, the both ends of storage shell (13) are opening, the setting film in folded state to be released in storage shell (13) Manage (7) and alimentary stent, the releaser setting at the distal openings of storage shell (13) and with the membrane tube (7) one End connection, the releaser by the material that human body intestinal canal is digested and assimilated or dissolved by that can be made;The alimentary stent has exhibition Shape and shape after expansion before opening, which is characterized in that the alimentary stent includes upper bracket (1), lower bracket (2) and connector (3);After deployment under shape, upper bracket (1) is closing on equipped with the first opening at the top of it and is being equipped with second closing on its bottom Opening, lower bracket (2) be set to upper bracket (1) below, lower bracket (2) close at the top of it be equipped with third be open and closing on it Bottom is equipped with the 4th opening, is connected between upper bracket (1) and lower bracket (2) by several connectors (3), lower bracket (2) 4th opening connection membrane tube (7), also, be unfolded after upper bracket (1) and lower bracket (2) can not pass through the stomach pylorus of opening Mouthful, connector (3) by pyloric ostium of stomach or can be threaded through at pyloric ostium of stomach.
2. a kind of stomach air deflector according to claim 1, which is characterized in that the connector (3) is connecting line, outside connecting line Face overlay film.
3. a kind of alimentary stent of stomach air deflector according to claim 2, which is characterized in that the connector (3) includes More connecting lines, the upper end of more connecting lines are separately connected upper bracket (1), and the lower end of more connecting lines is separately connected lower bracket (2)。
4. a kind of alimentary stent of stomach air deflector according to claim 2, which is characterized in that the connector (3) is right It answers the position of pyloric ostium of stomach that can generate in its natural state and complies with the bending of human body pyloric ostium or the elastic deformation of reduced outside diameter.
5. a kind of alimentary stent of stomach air deflector according to claim 2, which is characterized in that the upper bracket (1) is in Cone cylinder shape, back taper tubular, straight-tube shape or straw hat shape.
6. a kind of alimentary stent of stomach air deflector according to claim 2, which is characterized in that the upper bracket (1) Second opening outer diameter is greater than the first opening outer diameter.
7. a kind of alimentary stent of stomach air deflector according to claim 2, which is characterized in that the upper end of connecting line with it is upper Position at the top of bracket (1) close to the first opening is fixedly connected, and is open at the top of the lower end and lower bracket (2) of connecting line close to third Position be fixedly connected.
8. a kind of alimentary stent of stomach air deflector according to claim 2, which is characterized in that the upper end of connecting line with it is upper Position at the top of bracket (1) close to the first opening is fixedly connected, in the middle part of connecting line pile warp upper bracket (1) after mesh, connecting line Lower end is fixedly connected with the position at the top of lower bracket (2) close to third opening.
9. a kind of stomach air deflector according to any one of claim 1 to 8, which is characterized in that the storage shell (13) It is equipped with mark line (25).
10. a kind of method for releasing of stomach air deflector, including stomach air deflector as claimed in claim 9 and following step:
1) distal openings of shell (13) are stored in storage shell (13) in the membrane tube of folded state and alimentary stent setting It is closed by releaser;
2) under the guidance of seal wire, the releaser for storing shell (13) distal end is sent into duodenum, then by releaser and film Pipe releases storage shell;
3) storage shell is withdrawn again, until mark line reaches pyloric ostium, lower bracket is released from storage shell, lower bracket stays in Duodenal bulb;
4) storage shell is withdrawn again, and upper bracket is released from storage shell, allows upper bracket to stay in outside pyloric ostium, completes release.
CN201810336514.2A 2018-04-12 2018-04-12 Gastric inducer and method of releasing same Active CN108938163B (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CN201810336514.2A CN108938163B (en) 2018-04-12 2018-04-12 Gastric inducer and method of releasing same
EP18914681.4A EP3777784B1 (en) 2018-04-12 2018-10-24 Gastric diverter and digestive tract support and release method thereof
ES18914681T ES2934842T3 (en) 2018-04-12 2018-10-24 Gastric bypass and digestive tract support and its method of release
US16/981,322 US11517461B2 (en) 2018-04-12 2018-10-24 Gastric diverter and digestive tract support and release method thereof
PCT/CN2018/111746 WO2019196380A1 (en) 2018-04-12 2018-10-24 Gastric diverter and digestive tract support and release method thereof
PL18914681.4T PL3777784T3 (en) 2018-04-12 2018-10-24 Gastric diverter and digestive tract support and release method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810336514.2A CN108938163B (en) 2018-04-12 2018-04-12 Gastric inducer and method of releasing same

Publications (2)

Publication Number Publication Date
CN108938163A true CN108938163A (en) 2018-12-07
CN108938163B CN108938163B (en) 2023-12-26

Family

ID=64498623

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810336514.2A Active CN108938163B (en) 2018-04-12 2018-04-12 Gastric inducer and method of releasing same

Country Status (1)

Country Link
CN (1) CN108938163B (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020154149A1 (en) * 2019-01-22 2020-07-30 Lean Medical Technologies, Inc. Obesity treatment device and method
WO2020194189A1 (en) * 2019-03-25 2020-10-01 Bfkw, Llc Intraluminal device and method with anti-migration
CN113271899A (en) * 2019-01-03 2021-08-17 亚历山大·布茨 Gastrointestinal implant and positioning device thereof
US11504255B2 (en) 2007-02-14 2022-11-22 Bfkw, Llc Bariatric device and method
US11642234B2 (en) 2004-10-15 2023-05-09 Bfkw, Llc Bariatric device and method
US12127958B2 (en) 2021-09-24 2024-10-29 Bfkw, Llc Intraluminal device and method with anti-migration

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106923944A (en) * 2017-04-28 2017-07-07 杭州糖吉医疗科技有限公司 Enteron aisle isolates membrane tube release
CN106937898A (en) * 2012-07-13 2017-07-11 Gi动力公司 TP grappling
CN107126306A (en) * 2017-06-27 2017-09-05 杭州糖吉医疗科技有限公司 Stomach air deflector and its support
CN107308534A (en) * 2017-06-27 2017-11-03 杭州糖吉医疗科技有限公司 Stomach air deflector and its alimentary canal anti-microbial catheter

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106937898A (en) * 2012-07-13 2017-07-11 Gi动力公司 TP grappling
CN106923944A (en) * 2017-04-28 2017-07-07 杭州糖吉医疗科技有限公司 Enteron aisle isolates membrane tube release
CN107126306A (en) * 2017-06-27 2017-09-05 杭州糖吉医疗科技有限公司 Stomach air deflector and its support
CN107308534A (en) * 2017-06-27 2017-11-03 杭州糖吉医疗科技有限公司 Stomach air deflector and its alimentary canal anti-microbial catheter

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11642234B2 (en) 2004-10-15 2023-05-09 Bfkw, Llc Bariatric device and method
US11504255B2 (en) 2007-02-14 2022-11-22 Bfkw, Llc Bariatric device and method
CN113271899A (en) * 2019-01-03 2021-08-17 亚历山大·布茨 Gastrointestinal implant and positioning device thereof
CN113271899B (en) * 2019-01-03 2024-06-11 亚历山大·布茨 Gastrointestinal implant and positioning device thereof
WO2020154149A1 (en) * 2019-01-22 2020-07-30 Lean Medical Technologies, Inc. Obesity treatment device and method
CN113382697A (en) * 2019-01-22 2021-09-10 利恩医疗技术有限公司 Obesity treatment device and method
WO2020194189A1 (en) * 2019-03-25 2020-10-01 Bfkw, Llc Intraluminal device and method with anti-migration
US12127958B2 (en) 2021-09-24 2024-10-29 Bfkw, Llc Intraluminal device and method with anti-migration

Also Published As

Publication number Publication date
CN108938163B (en) 2023-12-26

Similar Documents

Publication Publication Date Title
CN108938163A (en) Stomach air deflector and its method for releasing
US7758535B2 (en) Bariatric sleeve delivery devices
US7678068B2 (en) Atraumatic delivery devices
JP5407048B2 (en) Weight loss device
US9962278B2 (en) Modular gastrointestinal prostheses
US8403877B2 (en) Systems and methods for treatment of obesity and type 2 diabetes
KR20190003628A (en) Anchorless gastric device for obesity treatment
JP2012152576A (en) Bariatric sleeve
CN109195529A (en) Flanged gastrointestinal device and its application method
CN108635092A (en) Stomach air deflector and its alimentary stent
CN208864588U (en) Stomach air deflector and its alimentary stent
CN107158546B (en) Stomach air deflector
EP3777784B1 (en) Gastric diverter and digestive tract support and release method thereof
US8911392B2 (en) Systems and methods for treatment of obesity and type 2 diabetes

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant