CN107899478A - Agitating device for bio-pharmaceuticals - Google Patents
Agitating device for bio-pharmaceuticals Download PDFInfo
- Publication number
- CN107899478A CN107899478A CN201711295285.6A CN201711295285A CN107899478A CN 107899478 A CN107899478 A CN 107899478A CN 201711295285 A CN201711295285 A CN 201711295285A CN 107899478 A CN107899478 A CN 107899478A
- Authority
- CN
- China
- Prior art keywords
- slave arm
- screw rod
- mixing drum
- arm
- bio
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229960000074 biopharmaceutical Drugs 0.000 title claims abstract description 15
- 230000008878 coupling Effects 0.000 claims abstract description 13
- 238000010168 coupling process Methods 0.000 claims abstract description 13
- 238000005859 coupling reaction Methods 0.000 claims abstract description 13
- 239000000463 material Substances 0.000 claims description 9
- 241000826860 Trapezium Species 0.000 claims description 3
- 229910001220 stainless steel Inorganic materials 0.000 claims description 3
- 239000010935 stainless steel Substances 0.000 claims description 3
- 238000003780 insertion Methods 0.000 claims description 2
- 230000037431 insertion Effects 0.000 claims description 2
- 239000003814 drug Substances 0.000 abstract description 18
- 238000003756 stirring Methods 0.000 abstract description 7
- 238000000034 method Methods 0.000 abstract description 6
- 239000000203 mixture Substances 0.000 abstract description 3
- 238000002360 preparation method Methods 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000003111 delayed effect Effects 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F29/00—Mixers with rotating receptacles
- B01F29/60—Mixers with rotating receptacles rotating about a horizontal or inclined axis, e.g. drum mixers
- B01F29/64—Mixers with rotating receptacles rotating about a horizontal or inclined axis, e.g. drum mixers with stirring devices moving in relation to the receptacle, e.g. rotating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F29/00—Mixers with rotating receptacles
- B01F29/40—Parts or components, e.g. receptacles, feeding or discharging means
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mixers Of The Rotary Stirring Type (AREA)
Abstract
The present invention relates to the agitating device for bio-pharmaceuticals, specifically it is used for the agitating device of bio-pharmaceuticals, it includes mixing drum, screw rod, helical blade, upper cover, is fastenedly connected lid, sunk screw, shaft coupling, motor, lower hopper, feed opening, spout plug, draw ring, fixed plate, base, rotating stand, master arm, the first slave arm, the second slave arm, the 3rd slave arm and annular holder；The screw rod is through upper cover and is inserted into inside mixing drum, and annular spread helical blade on screw rod excircle, screw tip is connected by shaft coupling with motor；Relative motion between the master arm and slave arm is by driving mechanism, guiding mechanism and numerical control operation console co- controlling.The present invention not only improves stirring efficiency and mixture homogeneity, but also realizes integrated, intelligentized requirement, accelerates the industrially prepared process of medicine.
Description
Technical field
The present invention relates to a kind of agitating device, the specifically agitating device for bio-pharmaceuticals.
Background technology
Pharmaceutical engineering is chemistry, biology, a pharmacy（Chinese pharmacology）The industry science class subject intersected with engineering science, and in
In the culture thinking of pharmacy, except the study for basic medicine knowledge, the ability of practice of preparation and production for medicine
It is particularly important that.
The mixed medicine process of stirring is to prepare indispensable flow during medicine, and the uniformity coefficient of medicine mixing influences drug effect, raw
The speed that the raising of production efficiency is uniformly mixed with medicine is closely related.For current technology of pharmaceutical engineering field, " Integrated manufacture
This concept of technology " has been penetrated into preparation flow, and target is the whole numerical control operating of realization.However, the most of medicines of in the market
Mixing plant is also not reaching to the requirement of the integrated control of computer, has delayed the preparation process of medicine.
The content of the invention
In view of the above-mentioned problems, the agitating device the present invention is provided to bio-pharmaceuticals.
Technical solution is used by the present invention solves above-mentioned technical problem：For the agitating device of bio-pharmaceuticals, including
Mixing drum, screw rod, helical blade, upper cover, be fastenedly connected lid, sunk screw, shaft coupling, motor, lower hopper, feed opening, outlet
Plug, draw ring, fixed plate, base, rotating stand, master arm, the first slave arm, the second slave arm, the 3rd slave arm and marmon clamp
Tool；The master arm（16）Relative motion between slave arm is common by driving mechanism, guiding mechanism and numerical control operation console
Control；It is connected at the top of the mixing drum by sunk screw with upper cover, screw rod is through upper cover and is inserted into inside mixing drum, screw rod
Connected between upper cover by being fastenedly connected lid, be fastenedly connected lid and be fixed on by sunk screw on upper lid, ring on screw rod excircle
Shape is distributed helical blade, and screw tip is connected with shaft coupling one end, and the shaft coupling other end is connected with motor；The upper cover upper end is set
Lower hopper is put, the top of lower hopper is feed opening, and mixing drum bottom sets discharge port, spout plug, spout plug bottom are set at material mouth
End sets a draw ring；
The base is arranged in fixed plate, and rotating stand is fixedly connected with base, and the circular configuration insertion of master arm bottom turns
In dynamic bearing, rotating range of the master arm on rotating stand is 0 ~ 360o, and master arm upper end connects with the first slave arm
Connect, the first slave arm is connected with the second slave arm, and the second slave arm is connected with the 3rd slave arm, the 3rd slave arm end and annular
Fixture connects, and annular holder is placed on mixing drum excircle.
Preferably, the cross sectional shape of the lower hopper is right-angled trapezium.
Preferably, the feed opening（10）It is provided with feeding switch.
Preferably, the annular holder is arranged on the medium position of mixing drum.
Preferably, the material of the mixing drum, screw rod and helical blade is stainless steel material.
Compared with prior art, the invention has the advantages that：
1st, the stirring on three-dimensional is realized in the relative motion between master arm and slave arm, and medicine rolls up and down makes mixing faster
Speed, improves stirring efficiency；
2nd, screw rod drives helical blade rotation, realizes the function of internal stirring, medicine be subject to the shearing force that helical blade gives and
The effect of centrifugal force, high-speed impact together, improve mixture homogeneity；
3rd, whipping process is operated by digital control system, realizes integrated, intelligentized requirement, is saved manpower, is accelerated the industry of medicine
Preparation process.
Brief description of the drawings
Fig. 1 is the schematic diagram for the agitating device that the present invention is used for bio-pharmaceuticals.
Fig. 2 is the front view for the agitating device that the present invention is used for bio-pharmaceuticals.
Fig. 3 is the whipping process schematic diagram for the agitating device that the present invention is used for bio-pharmaceuticals.
In figure, 1- mixing drums, 2- screw rods, 3- helical blades, 4- upper covers, 5- is fastenedly connected lid, 6- sunk screws, 7- shaft couplings
Device, 8- motors, 9- lower hoppers, 10- feed openings, 11- spout plugs, 12- draw rings, 13- fixed plates, 14- bases, 15- rotating stands,
16- active walls, the first slave arms of 17-, the second slave arms of 18-, the 3rd slave arms of 19-, 20- annular holders.
Embodiment
Below in conjunction with Fig. 1 ~ Fig. 3, the present invention will be described in detail, and illustrative examples and explanation of the invention are used for herein
Explain the present invention, but it is not as a limitation of the invention.
For the agitating device of bio-pharmaceuticals, including mixing drum 1, screw rod 2, helical blade 3, upper cover 4, be fastenedly connected lid 5,
Sunk screw 6, shaft coupling 7, motor 8, lower hopper 9, feed opening 10, spout plug 11, draw ring 12, fixed plate 13, base 14, rotation
Bearing 15, master arm 16, the first slave arm 17, the second slave arm 18, the 3rd slave arm 19 and annular holder 20；The mixing drum
1 top is connected by sunk screw 6 with upper cover 4, and screw rod 2 is through upper cover 4 and is inserted into inside mixing drum 1, screw rod 2 and upper cover 4
Between connected by being fastenedly connected lid 5, be fastenedly connected lid 5 and be fixed on by sunk screw 6 in upper cover 4, it is annular on 2 excircle of screw rod
Helical blade 3 is distributed, 2 top of screw rod is connected with 4 one end of shaft coupling, and 4 other end of shaft coupling is connected with motor 8；In the upper cover 4
End sets lower hopper 9, and the top of lower hopper 9 is feed opening 10, and 1 bottom of mixing drum sets discharge port, spout plug is set at material mouth
11,11 bottom of spout plug sets a draw ring 12.The base 14 is arranged in fixed plate 13, and rotating stand 15 is solid with base 14
Fixed connection, the circular configuration of 16 bottom of master arm are inserted into rotating stand 15, and 16 upper end of master arm is connected with the first slave arm 17,
First slave arm 17 is connected with the second slave arm 18, and the second slave arm 18 is connected with the 3rd slave arm 19,19 end of the 3rd slave arm
Portion is connected with annular holder 20, and annular holder 20 is placed on 1 excircle of mixing drum.
Roughness Ra≤3.2 μm of 1 inner wall of mixing drum.The mixing drum 1, screw rod 2 and the helical-blade
The material of piece 3 is stainless steel material.The cross sectional shape of the lower hopper 9 is right-angled trapezium.The feed opening 10 is set
There is feeding switch.Rotating range of the master arm 16 on rotating stand 15 is 0 ~ 360o.The master arm 16 with from
Relative motion between swing arm is by driving mechanism, guiding mechanism and numerical control operation console co- controlling.The annular holder 20 is set
Put the medium position in mixing drum 1.
In implementation process, it would be desirable to which the medicine being stirred is put into from feed opening 10, and medicine falls into along lower hopper 9 and stirs
Mix in cylinder 1, start motor 8, rotated by shaft coupling 7 and drive screw rod 2 to rotate, and then drive screw thread blade 3 to rotate；Start at the same time
Driving shaft 16 moves, and driving shaft 16 is rotated around rotating stand 15, while drives slave arm to move, and mixing drum 1 is realized upset
Stirring, makes the mixing of medicine more efficiently, uniformly.After medicine mixing is completed, draw ring 12 is pulled, extracts spout plug 11, mixing
Medicine outflow afterwards, completes to be stirred process to medicine.
The technical solution provided above the embodiment of the present invention is described in detail, specific case used herein
The principle and embodiment of the embodiment of the present invention are set forth, the explanation of above example is only applicable to help and understands this
The principle of inventive embodiments；Meanwhile for those of ordinary skill in the art, according to the embodiment of the present invention, in specific embodiment party
There will be changes in formula and application range, in conclusion this specification content should not be construed as limiting the invention.
Claims (5)
1. the agitating device for bio-pharmaceuticals, it is characterised in that：Including mixing drum（1）, screw rod（2）, helical blade（3）, on
Lid（4）, be fastenedly connected lid（5）, sunk screw（6）, shaft coupling（7）, motor（8）, lower hopper（9）, feed opening（10）, spout plug
（11）, draw ring（12）, fixed plate（13）, base（14）, rotating stand（15）, master arm（16）, the first slave arm（17）, second
Slave arm（18）, the 3rd slave arm（19）And annular holder（20）；The master arm（16）Opposite fortune between slave arm
Move by driving mechanism, guiding mechanism and numerical control operation console co- controlling；The mixing drum（1）Top passes through sunk screw（6）With
Upper cover（4）Connection, screw rod（2）Through upper cover（4）And it is inserted into mixing drum（1）Inside, screw rod（2）With upper cover（4）Between pass through
It is fastenedly connected lid（5）Connection, is fastenedly connected lid（5）By sunk screw（6）It is fixed on upper cover（4）On, screw rod（2）Ring on excircle
Shape is distributed helical blade（3）, screw rod（2）Top and shaft coupling（4）One end connects, shaft coupling（4）The other end and motor（8）Even
Connect；
The upper cover（4）Upper end sets lower hopper（9）, lower hopper（9）Top be feed opening（10）, mixing drum（1）Bottom is set
Discharge port is put, spout plug is set at material mouth（11）, spout plug（11）Bottom sets a draw ring（12）；
The base（14）It is arranged on fixed plate（13）On, rotating stand（15）With base（14）It is fixedly connected, master arm（16）
The circular configuration insertion rotating stand of bottom（15）In, the master arm（16）In rotating stand（15）On rotating range be
0~360º；Master arm（16）Upper end and the first slave arm（17）Connection, the first slave arm（17）With the second slave arm（18）Connection,
Second slave arm（18）With the 3rd slave arm（19）Connection, the 3rd slave arm（19）End and annular holder（20）Connection, annular
Fixture（20）It is placed on mixing drum（1）On excircle.
2. it is used for the agitating device of bio-pharmaceuticals according to claim 1, it is characterised in that：The lower hopper（9）Cut
Face shape is right-angled trapezium.
3. it is used for the agitating device of bio-pharmaceuticals according to claim 1, it is characterised in that：The feed opening（10）Set
There is feeding switch.
4. it is used for the agitating device of bio-pharmaceuticals according to claim 1, it is characterised in that：The annular holder（20）If
Put in mixing drum（1）Medium position.
A kind of 5. medicinal mixing plant according to claim 2, it is characterised in that：The mixing drum（1）, screw rod（2）And
Helical blade（3）Material be stainless steel material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711295285.6A CN107899478A (en) | 2017-12-08 | 2017-12-08 | Agitating device for bio-pharmaceuticals |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711295285.6A CN107899478A (en) | 2017-12-08 | 2017-12-08 | Agitating device for bio-pharmaceuticals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107899478A true CN107899478A (en) | 2018-04-13 |
Family
ID=61854637
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711295285.6A Pending CN107899478A (en) | 2017-12-08 | 2017-12-08 | Agitating device for bio-pharmaceuticals |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107899478A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117065516A (en) * | 2023-10-16 | 2023-11-17 | 华能左权煤电有限责任公司 | Flue gas desulfurization device suitable for coal fired power plant |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006061183A (en) * | 2004-08-24 | 2006-03-09 | Nakai Kikai Kogyo Kk | Universal agitator for various foodstuff |
| JP2015502863A (en) * | 2011-12-02 | 2015-01-29 | アエシント トプコ ベスローテン フェンノートシャップ | System and method for re-preparing a powdered drug |
| CN205868132U (en) * | 2016-05-24 | 2017-01-11 | 巢湖学院 | Three degree of freedom oscillating mixer |
| CN107281958A (en) * | 2017-07-26 | 2017-10-24 | 汪培杰 | A kind of outfit device of gardens Nutrition Soil |
-
2017
- 2017-12-08 CN CN201711295285.6A patent/CN107899478A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006061183A (en) * | 2004-08-24 | 2006-03-09 | Nakai Kikai Kogyo Kk | Universal agitator for various foodstuff |
| JP2015502863A (en) * | 2011-12-02 | 2015-01-29 | アエシント トプコ ベスローテン フェンノートシャップ | System and method for re-preparing a powdered drug |
| CN205868132U (en) * | 2016-05-24 | 2017-01-11 | 巢湖学院 | Three degree of freedom oscillating mixer |
| CN107281958A (en) * | 2017-07-26 | 2017-10-24 | 汪培杰 | A kind of outfit device of gardens Nutrition Soil |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117065516A (en) * | 2023-10-16 | 2023-11-17 | 华能左权煤电有限责任公司 | Flue gas desulfurization device suitable for coal fired power plant |
| CN117065516B (en) * | 2023-10-16 | 2023-12-19 | 华能左权煤电有限责任公司 | Flue gas desulfurization device suitable for coal fired power plant |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180413 |
|
| RJ01 | Rejection of invention patent application after publication |