CN107897016B - Device for feeding reptiles in upright state - Google Patents
Device for feeding reptiles in upright state Download PDFInfo
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- CN107897016B CN107897016B CN201711379999.5A CN201711379999A CN107897016B CN 107897016 B CN107897016 B CN 107897016B CN 201711379999 A CN201711379999 A CN 201711379999A CN 107897016 B CN107897016 B CN 107897016B
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- 241000938605 Crocodylia Species 0.000 title claims abstract description 26
- 241000270322 Lepidosauria Species 0.000 claims abstract description 41
- 230000035622 drinking Effects 0.000 claims abstract description 15
- 230000000384 rearing effect Effects 0.000 claims description 5
- 238000010171 animal model Methods 0.000 abstract description 22
- 206010061246 Intervertebral disc degeneration Diseases 0.000 abstract description 18
- 208000018180 degenerative disc disease Diseases 0.000 abstract description 17
- 208000021600 intervertebral disc degenerative disease Diseases 0.000 abstract description 17
- 238000000034 method Methods 0.000 abstract description 9
- 238000011160 research Methods 0.000 abstract description 5
- 235000021590 normal diet Nutrition 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 description 9
- 241000282414 Homo sapiens Species 0.000 description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 241000283973 Oryctolagus cuniculus Species 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 241000894007 species Species 0.000 description 4
- 230000007547 defect Effects 0.000 description 3
- 230000001575 pathological effect Effects 0.000 description 3
- 241000282472 Canis lupus familiaris Species 0.000 description 2
- 241000282693 Cercopithecidae Species 0.000 description 2
- 241000699670 Mus sp. Species 0.000 description 2
- 208000037273 Pathologic Processes Diseases 0.000 description 2
- 241001494479 Pecora Species 0.000 description 2
- 241000700159 Rattus Species 0.000 description 2
- 241000282887 Suidae Species 0.000 description 2
- 210000003484 anatomy Anatomy 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000008506 pathogenesis Effects 0.000 description 2
- 230000009054 pathological process Effects 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 208000008035 Back Pain Diseases 0.000 description 1
- 208000008930 Low Back Pain Diseases 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 206010028391 Musculoskeletal Pain Diseases 0.000 description 1
- 206010028836 Neck pain Diseases 0.000 description 1
- 206010033425 Pain in extremity Diseases 0.000 description 1
- 241001504519 Papio ursinus Species 0.000 description 1
- 208000007613 Shoulder Pain Diseases 0.000 description 1
- 230000037237 body shape Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 208000015122 neurodegenerative disease Diseases 0.000 description 1
- 210000000278 spinal cord Anatomy 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 210000001364 upper extremity Anatomy 0.000 description 1
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K1/00—Housing animals; Equipment therefor
- A01K1/02—Pigsties; Dog-kennels; Rabbit-hutches or the like
- A01K1/03—Housing for domestic or laboratory animals
- A01K1/031—Cages for laboratory animals; Cages for measuring metabolism of animals
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K1/00—Housing animals; Equipment therefor
- A01K1/02—Pigsties; Dog-kennels; Rabbit-hutches or the like
- A01K1/035—Devices for use in keeping domestic animals, e.g. fittings in housings or dog beds
- A01K1/0356—Feeding or drinking devices associated with cages
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K15/00—Devices for taming animals, e.g. nose-rings or hobbles; Devices for overturning animals in general; Training or exercising equipment; Covering boxes
- A01K15/02—Training or exercising equipment, e.g. mazes or labyrinths for animals ; Electric shock devices ; Toys specially adapted for animals
- A01K15/027—Exercising equipment, e.g. tread mills, carousels
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
- Y02A40/81—Aquaculture, e.g. of fish
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- Life Sciences & Earth Sciences (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Birds (AREA)
- Clinical Laboratory Science (AREA)
- Housing For Livestock And Birds (AREA)
Abstract
A device for raising a reptile model in an upright position. The device comprises a cage body frame, a fixed cylinder, a movable cylinder, a longitudinal slide way, a transverse slide way, a feeding cylinder and a drinking cylinder, wherein the fixed cylinder is arranged in the cage body frame, the feeding cylinder and the drinking cylinder are fixed at the upper corner of the cage body frame, the longitudinal slide way and the transverse slide way are fixedly arranged on the cage body frame, and the movable cylinder is connected with the transverse slide way or the longitudinal slide way through a sliding ring. In the feeding process, the reptiles are placed in the fixed cylinder and then integrally moved into the movable cylinder, so that the reptiles are in an upright state, and can rotate between the fixed cylinder and the movable cylinder and can move forwards, backwards, leftwards and rightwards by virtue of the longitudinal slide way and the transverse slide way. The feeding cylinder and the drinking cylinder can ensure the normal diet of the reptiles. The invention not only can ensure that the reptile is in an upright state at any time, but also can ensure the free movement of the reptile, so that the invention can meet the conditions for constructing the intervertebral disc degeneration upright animal model, and provides an ideal experimental device for relevant experimental research.
Description
Technical Field
The invention belongs to the field of animal raising devices, and particularly relates to a fixing device for fixing a reptile to enable the reptile to freely move in an upright state.
Background
Disc degeneration (intervertebral disc degeneration, IVDD) is a prerequisite and fundamental pathological process of a series of spinal degenerative diseases, and is clinically manifested by neck and shoulder pain, lumbago and leg pain, etc., and the nerve root and spinal cord related to patients are stressed and produce a series of corresponding symptoms. At present, the etiology and pathogenesis of the IVDD are not completely elucidated, and a reliable animal model is established through researching an intervertebral disc degeneration variable model, so that a good research object and experimental carrier can be provided for researching the etiology and pathogenesis of the IVDD. Although many studies have been made to establish an intervertebral disc degeneration model by various methods including a spontaneous intervertebral disc degeneration model, an intervertebral disc degeneration model caused by stress change, an intervertebral disc degeneration model caused by spinal instability, a chemically prepared animal model, a genetically modified or knocked-out prepared animal model, and a surgically damaged animal model, none of the well-recognized and reliable modeling methods have been widely used so far.
At present, more common animal species used for constructing the intervertebral disc degeneration animal model are mice, rabbits, sheep, dogs, pigs and the like, and the species have common characteristics, namely, all the species are reptiles, the physiological structure of the spinal column of the species is opposite to that of an upright human, and after the animal model is built, the life habit of the reptiles is an important factor influencing experimental results; in addition, the monkey and baboon with similar relativity to human are ideal model animals, can walk upright on two feet, have similar spine structure and similar biomechanical factors carried by the spine to human, thus building a model of monkey intervertebral disc degeneration for researching pathological processes of human intervertebral disc degeneration is the most true and reliable, but has the related problems of rare sources, high price, inconvenient feeding, ethics and the like, thereby limiting the application of the model animals.
For the above reasons, the following should be satisfied in selecting, preparing a model of intervertebral disc degeneration, the species: (1) The process of intervertebral disc degeneration of model animals and human has similarity and comparability; (2) good repeatability; (3) has easy operability and economy. Therefore, if a reptile can be changed to an upright life habit, such an experimental animal becomes the first choice for building up an intervertebral disc degeneration model. However, large mammals such as pigs, dogs and sheep have the defects of high price and inconvenient feeding, so that the animals are not widely applied to the preparation of intervertebral disc degeneration animal models; the experimental animals widely used for preparing the intervertebral disc degeneration animal model in the experimental research of the IVDD are rats and white rabbits.
To overcome the defects of the two animals in terms of anatomical structures and biomechanics, a learner adopts an artificial method to force the two animals to stand, such as cutting the upper limbs of rats to establish a bipedal upright animal model; the white rabbits are placed in a specially-made cylinder to keep a straight three-dimensional position and are longitudinally pressurized to build an animal model, and the vertical animal model is built by adopting corresponding measures, so that the pathological mechanism of the pathological intervertebral discs can be further researched by the stimulation of mechanical factors. However, the method is more forgiving to experimental animals and is not beneficial to popularization.
Disclosure of Invention
In view of the above-mentioned drawbacks of the prior art, the present invention provides a feeding apparatus for reptiles in an upright position in order to solve the problem of creating animal models and eliminating the biomechanical disturbances of the reptile's spine.
The invention aims to enable a reptile to be in an upright state by utilizing a fixed cylinder and a movable cylinder and to freely move, so that the spine of the reptile can bear vertical and axial downward force, and the constructed animal model is similar to the stress mode of the spine of a human being as far as possible.
The technical scheme for achieving the aim is as follows: an apparatus for feeding a reptile model in an upright position, the apparatus comprising: the food feeding device comprises a reptile cage body frame, a fixed barrel, a movable barrel, a longitudinal slideway, a transverse slideway, a food feeding barrel and a water drinking barrel, wherein the fixed barrel is placed in the cage body frame, the food feeding barrel and the water drinking barrel are fixed at the upper corners of the cage body frame, the longitudinal slideway is sleeved on the transverse slideway through a slip ring, two ends of the longitudinal slideway are installed and fixed on the cage body frame through fixing rods, and the movable barrel is fixedly connected with the transverse slideway or the longitudinal slideway through a slip ring. In the feeding process, the reptiles are placed in the fixed cylinder and then integrally moved into the movable cylinder, the reptiles are in an upright state at the moment, can rotate 360 degrees by means of the gap between the fixed cylinder and the movable cylinder, and can move forwards, backwards, leftwards and rightwards by means of the longitudinal and transverse slideways. The feeding cylinder and the drinking cylinder ensure that the reptiles eat and drink water normally. The invention not only can ensure that the reptile is in an upright state at any time, but also can ensure that the reptile can freely move. Therefore, the method can meet the conditions for constructing the intervertebral disc degeneration upright animal model, and provides an experimental animal model device for relevant experimental research.
Further, the fixed cylinder is made of a PVC pipe with the diameter equal to that of the trunk of the reptile, the fixed cylinder is assembled by two arc-shaped blades, and the PVC pipe is provided with a hinge at the half pipe diameter, so that the reptile can be conveniently opened and closed to be placed, and the reptile is ensured to be in an upright state.
Further, the movable cylinder is formed by assembling four arc-shaped blades, an adjusting knob mechanism is arranged between two blade gaps, and the gap distance is adjusted through the adjusting knob, so that the diameter of the movable cylinder is adjusted. The movable cylinder is connected with the longitudinal slide way and the transverse slide way, and the diameter of the movable cylinder is adjusted to enable the movable cylinder to accommodate the fixed cylinder, so that 360-degree rotation movement between the fixed cylinder and the movable cylinder is realized.
Further, the water drinking barrel and the feeding barrel are provided with lifting adjusting knobs which are fixed on the whole device, and the lifting rotation can adjust the height of the water drinking barrel so as to be convenient for feeding animals with different heights or be used for adjusting the height along with the growth of the body of the reptile, thereby ensuring the normal feeding and drinking of the reptile.
In another preferred embodiment, the fixed cylinder can be opened and closed by a hinge to enable the reptile to be in an upright state, and the inner diameter of the fixed cylinder is equal to the diameter of the trunk of the reptile, so that the inner diameter of the fixed cylinder does not damage the trunk of the reptile.
In another preferred embodiment, the diameter of the movable cylinder is slightly larger than that of the fixed cylinder and a proper gap is reserved through four adjusting knobs on the periphery of the movable cylinder, so that 360-degree rotation movement between the fixed cylinder and the movable cylinder is realized. And slip rings are arranged on two sides of the movable cylinder and are used for connecting the transverse slide ways, so that the fixed cylinder and the movable cylinder can integrally move left and right. And slip rings are arranged at two ends of the transverse slideway and are used for connecting the longitudinal slideway, so that the fixed cylinder, the movable cylinder and the transverse slideway can integrally move forwards and backwards.
Further, the longitudinal slide ways are fixed on the two side walls of the rearing cage through the adjusting knob, and the overall height of the movable barrel, the containing fixed barrel, the connecting transverse slide ways and the longitudinal slide ways can be adjusted along with the growth speed of the reptiles.
The invention has the following beneficial effects:
(1) The feeding device enables the reptiles to be in an upright state, overcomes the defects of the reptiles in terms of anatomical structures and biomechanics, and enables the upright animal model established by relevant experimental researches to better meet experimental requirements. For example, the intervertebral disc degeneration model can enable the diseased intervertebral disc to bear the stimulation of mechanical factors so as to further study the pathological occurrence and development mechanism.
(2) The reptile can realize 360-degree rotation and all-directional activities of front, back, left and right by means of the fixed cylinder, the movable cylinder, the transverse slideway and the longitudinal slideway, so that the established animal model is more similar to the spinal mechanics bearing mechanism of human beings in terms of biomechanical mechanism.
(3) The feeding device can be used for a reptile model in an upright state required by related experiments, can increase the autonomous activity of the reptile, and furthest reduces the damage to experimental animals.
Drawings
Fig. 1 is a schematic view of the overall structure of the reptile rearing cage of the present invention in an upright position.
Fig. 2 is a schematic structural view of the reptile holding cylinder of the present invention.
As shown in the figure: the novel multifunctional food dispenser comprises a 1-cage body frame, a 2-fixed cylinder, a 3-movable cylinder, a 4-movable cylinder adjusting knob, a 5-transverse slideway, a 6-longitudinal slideway, a 7-longitudinal slideway fixing rod, an 8-slip ring, a 9-longitudinal slideway fixing rod height adjusting knob, a 10-feeding cylinder, a 11-feeding cylinder fixing adjusting knob, a 12-drinking cylinder, a 13-drinking cylinder fixing adjusting knob, a 14-fixed cylinder two-blade connecting hinge and a 15-fixed cylinder two-blade opening shape.
Detailed Description
The conception, specific structure, and technical effects of the present invention will be further described with reference to the accompanying drawings to fully understand the objects, features, and effects of the present invention.
The reptile rearing cage is assembled under the upright state, the movable cylinder 3 is connected with the slip ring of the transverse slideway 6, the longitudinal slideway fixing rods 7 around the slideway system are fixed on the cage body frame 1, and the height of the fixing rods is adjusted through the longitudinal slideway fixing rod height adjusting knob. The fixed cylinder is made of PVC pipes with the diameter equivalent to that of the trunk of the reptile, the fixed cylinder is assembled by two arc-shaped blades 15, the PVC pipes are provided with hinges 14 at the half pipe diameter, and fastening devices are arranged at the closing positions of the blades, so that the reptile can be conveniently opened and closed.
The moving cylinder 3 is opened by the adjusting knobs 4 on the upper and lower circumferences of the moving cylinder 3, the reptiles are placed in the moving cylinder 3 together with the fixed cylinder 2, and the fixed cylinder and the moving cylinder have no barrel bottom and are in an up-down straight-through shape. At the moment, the reptiles can freely move, eat and drink water under the vertical state by virtue of the slideway system.
When the invention is used for feeding the reptiles, the reptile fixing cylinder 2 is opened, the reptiles are placed in the reptile fixing cylinder, and the fixing cylinder is closed.
The adjustment knob of the movable cylinder is adjusted to be opened, so that the movable cylinder is in an open state, the reptiles and the fixed cylinder can be placed in the movable cylinder, and the adjustment knob of the movable cylinder is adjusted to be closed.
The reptile can do lateral movement by means of the lateral slideway and the lateral slip ring, and can also do longitudinal movement by means of the longitudinal slideway and the longitudinal slip ring, and the slideway system can ensure that the reptile can freely move in the rearing cage and can do 360-degree rotation movement between the fixed cylinder and the movable cylinder.
In the experimental process, the reptiles can naturally develop and grow, and when the weight and the body shape are increased, the diameters of the fixed cylinder and the movable cylinder are adjusted according to the trunk diameter of the reptiles by adjusting the adjusting knobs at the corresponding parts, so that the growth and the development of the reptiles are not influenced; when the length of the reptile rises, the height of the longitudinal slideway fixing rod is adjusted by adjusting the height adjusting knob, so that the slideway system is suitable for the height of the reptile; the height of the feeding barrel adjusting knob and the height of the drinking barrel adjusting knob are adjusted, so that the feeding barrel adjusting knob is suitable for the height of reptiles, and natural feeding and drinking are ensured. The adjusting knob is a bolt screw thread connecting component. The reptiles of the invention are more suitable for white mice or rabbits.
The foregoing describes in detail preferred embodiments of the present invention. It should be understood that the reptile upright model established by the laboratory researchers in the field can be modified and simply changed to conduct related studies in accordance with the concepts of the present invention. Therefore, all technical solutions which can be obtained by simple and flexible experiments on the basis of the prior art according to the inventive concept by a person skilled in the art shall be included in the scope of protection defined by the claims of the present invention.
Claims (4)
1. An apparatus for feeding a reptile model in an upright position, the apparatus comprising: the feeding device comprises a reptile cage body frame, a fixed cylinder, a movable cylinder, a longitudinal slideway, a transverse slideway, a feeding cylinder and a drinking cylinder, wherein the fixed cylinder is arranged in the cage body frame, the feeding cylinder and the drinking cylinder are fixed at the upper corner of the cage body frame, the longitudinal slideway is sleeved on the transverse slideway through a slip ring, two ends of the longitudinal slideway are fixed on the cage body frame through a fixed rod, and the movable cylinder is fixedly connected with the transverse slideway or the longitudinal slideway through a slip ring; the movable cylinder is assembled by four arc-shaped blades, an adjusting knob mechanism is arranged between the gaps of the two blades, and the diameter of the movable cylinder is adjusted by adjusting the gap distance through the adjusting knob; the diameter of the movable cylinder can be adjusted to accommodate the fixed cylinder, and the fixed cylinder can be mutually matched and rotated; the movable cylinder can move left and right on the transverse slideway after being contained in the fixed cylinder; the longitudinal slide ways are fixed on the two side walls of the rearing cage through the adjusting knob, and the overall height of the movable barrel, the containing fixed barrel, the connecting transverse slide ways and the longitudinal slide ways can be adjusted along with the growth speed of the reptiles; the feeding barrel is provided with an adjusting knob which is fixed on the wall of the feeding cage, and the adjusting knob can adjust the height of the feeding barrel, so that the feeding of reptiles is facilitated.
2. The apparatus of claim 1, wherein the fixed cylinder is made of a PVC pipe having a diameter corresponding to the diameter of the trunk of the reptile, and is assembled by two arc-shaped blades, and the PVC pipe is provided with a hinge at a half-diameter portion to facilitate the opening and closing of the reptile.
3. The apparatus of claim 1, wherein the drinking bowl has an adjustment knob secured to the wall of the feeder cage, the adjustment knob being operable to adjust the height of the bowl to facilitate drinking of the reptile.
4. The apparatus of claim 1 or 2, wherein the fixed cylinder and the movable cylinder have no barrel bottom and are straight-through.
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CN201711379999.5A CN107897016B (en) | 2017-12-20 | 2017-12-20 | Device for feeding reptiles in upright state |
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CN201711379999.5A CN107897016B (en) | 2017-12-20 | 2017-12-20 | Device for feeding reptiles in upright state |
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CN107897016A CN107897016A (en) | 2018-04-13 |
CN107897016B true CN107897016B (en) | 2023-05-19 |
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CN109528341B (en) * | 2018-11-15 | 2021-06-04 | 南方医科大学第三附属医院(广东省骨科研究院) | Molding equipment, molding method and application of mouse intervertebral disc degeneration model |
CN109938871B (en) * | 2019-03-22 | 2020-06-02 | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | External fixing device suitable for vertical experiment and use method thereof |
CN115399248B (en) | 2022-08-23 | 2024-01-23 | 中国人民解放军空军军医大学 | Comprehensive animal feeding device and method |
Citations (4)
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CN203120680U (en) * | 2013-03-11 | 2013-08-14 | 辽宁中医药大学 | Unloading weightlessness simulation device for hind legs of laboratory mice |
CN204016540U (en) * | 2014-04-30 | 2014-12-17 | 瑞普(天津)生物药业有限公司 | A kind of fowl restraining device |
CN204443551U (en) * | 2015-02-07 | 2015-07-08 | 刘博文 | A kind of bioconversion medium animal husbandry cage |
CN106073932A (en) * | 2016-05-29 | 2016-11-09 | 中国人民解放军海军总医院 | Lumbar Intervertebral Disc Degeneration animal model biomechanics molding machine |
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US7467602B2 (en) * | 2004-02-27 | 2008-12-23 | Dai-Dan Co., Ltd. | Breeding device for laboratory animal |
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---|---|---|---|---|
CN203120680U (en) * | 2013-03-11 | 2013-08-14 | 辽宁中医药大学 | Unloading weightlessness simulation device for hind legs of laboratory mice |
CN204016540U (en) * | 2014-04-30 | 2014-12-17 | 瑞普(天津)生物药业有限公司 | A kind of fowl restraining device |
CN204443551U (en) * | 2015-02-07 | 2015-07-08 | 刘博文 | A kind of bioconversion medium animal husbandry cage |
CN106073932A (en) * | 2016-05-29 | 2016-11-09 | 中国人民解放军海军总医院 | Lumbar Intervertebral Disc Degeneration animal model biomechanics molding machine |
Non-Patent Citations (1)
Title |
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