CN107890587A - A kind of medical eye speculum antimicrobial coating - Google Patents

A kind of medical eye speculum antimicrobial coating Download PDF

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Publication number
CN107890587A
CN107890587A CN201711222345.1A CN201711222345A CN107890587A CN 107890587 A CN107890587 A CN 107890587A CN 201711222345 A CN201711222345 A CN 201711222345A CN 107890587 A CN107890587 A CN 107890587A
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CN
China
Prior art keywords
antimicrobial coating
eye speculum
medical eye
coating according
parts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201711222345.1A
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Chinese (zh)
Inventor
卢晔
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Chengdu Chuangkezhijia Technology Co Ltd
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Chengdu Chuangkezhijia Technology Co Ltd
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Priority to CN201711222345.1A priority Critical patent/CN107890587A/en
Publication of CN107890587A publication Critical patent/CN107890587A/en
Withdrawn legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/02Surgical instruments, devices or methods, e.g. tourniquets for holding wounds open; Tractors
    • A61B17/0231Surgical instruments, devices or methods, e.g. tourniquets for holding wounds open; Tractors for eye surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F283/00Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
    • C08F283/002Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polymers modified by after-treatment
    • C08F283/004Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polymers modified by after-treatment modified by incorporation of silicium atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831Material properties
    • A61B2017/00889Material properties antimicrobial, disinfectant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/216Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with other specific functional groups, e.g. aldehydes, ketones, phenols, quaternary phosphonium groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The invention discloses a kind of medical eye speculum antimicrobial coating, belong to medical field, described antimicrobial coating is a kind of polymer coating, described polymer coating is a kind of makrolon multi-monomer grafting polymer, and described grafted monomers include containing phenyl ring or pyridine ring unsaturated silane and acrylonitrile monemer.

Description

A kind of medical eye speculum antimicrobial coating
Technical field
The present invention relates to area of medical devices, a kind of specifically eye speculum antimicrobial coating.
Background technology
Eyelid(eyelids)Eyelid is commonly called as, in front of eyeball, forms the barrier of protection eyeball.Eyelid divides upper eyelid with Eyelid, usually require to expand eyelid in order to perform the operation when carrying out operated eye.It is used to strut when eye speculum is a kind of operated eye Patient's eyelid is easy to the utensil of operation, is advantageous to expand surgical field of view.Eye speculum is equivalent to the drag hook in ophthalmologic operation, in ophthalmology In operation, play a part of supporting eyelid, use is quite varied, the eye speculum less stable of prior art, while easily makes Obtain relieving eye strain.
The cleaning of this eye speculum simultaneously is also a problem, and it is thin that resistance is once infected with the eye speculum surface being not easily cleaned Bacterium, patient will be made to face the risk of secondary infection.
The content of the invention
It is an object of the invention in order to solve the above problems, disclose a kind of medical eye speculum, including support frame, clamping Device, jig arm, one end of described jig arm and support frame are hinged, and the other end of described jig arm is fixedly connected with hook portion, support The centre of frame is provided with passage, and center-pole passes through passage, and the end of center-pole is hinged with head rod, and the second connecting rod is two Individual, one end of head rod and center-pole are hinged, and the other end and jig arm are hinged, and the top of center-pole is relative for control centre's bar The movable clamping device of support frame;
Described clamping device includes the fixing pipe being fixedly connected with support frame, and the end of described fixing pipe is hinged with handle, Described handle is two, and described handle is the grip structure of pliers, and center-pole passes through fixing pipe, and the end of center-pole is hinged There is the second connecting rod two, one end of the second connecting rod and the end of center-pole are hinged, and the other end and handle are hinged, and clamp handle Hand, the second connecting rod control centre bar control the contraction of jig arm toward post-tensioning, reduce the distance between hook portion, open handle, Center-pole is moved forward, and jig arm is opened.
As an improvement, described center-pole and the connection end of handle are provided with articulated joint, described articulated joint is hinged with second Connecting rod, the second described articulated joint and center-pole are threaded connection, while fixing pipe can be rotated with relative support frame, rotating hinge Joint, articulated joint can move along the axial direction of center-pole, can adjust the elasticity of clamping device.
As an improvement, described described support frame center is provided with passage, vias inner walls are screw thread, and fixing pipe passes through passage It is threadedly coupled with support frame, articulated joint can do radial rotating with respect to center-pole, rotate fixing pipe, fixing pipe can be along support The passage axial movement of frame;One of them of described jig arm is provided with the transfusion road that is connected with hook portion, and described transfusion road is by medicine Liquid is transported to hook portion and moistens eyes, and the transfusion road end in jig arm connects the sebific duct for providing decoction.
As an improvement, the hook surface of described eye speculum is provided with one layer of polymeric coating, described polymer coating It is a kind of makrolon multi-monomer grafting polymer, it is characterised in that described grafted monomers include containing phenyl ring or pyridine Ring unsaturated silane and acrylonitrile monemer.
As an improvement, described unsaturated silane monomer is selected from:Triple phenoxyl vinyl silanes, 3- chloropropyl dimethyl second Alkenyl silanes, triphenyl vinyl silane, 3,5-dimethylphenyl vinyl silanes, dimethyl (2- pyridine radicals) vinyl silanes.
As an improvement, described polymer and grafted monomers parts by weight of raw materials is as follows:100 parts of makrolon, unsaturated silicon Alkane monomer 5-20 parts, acrylonitrile monemer 5-20 parts.
Medical eye speculum according to claim 6, it is characterised in that the preparation method of described polymer coating is such as Under:
Step A:Unsaturated silane, acrylonitrile are uniformly mixed;
Step B:Makrolon is melted in rheometer;
Step C:Mixture and initiator after step A are added in rheometer, react 5 min -10min..
Described initiator is selected from benzoyl peroxide, lauroyl peroxide, isopropyl benzene hydroperoxide, tert-butyl hydroperoxide Hydrogen, cumyl peroxide.Described initiator is the mixture of benzoyl peroxide and cumyl peroxide, and mol ratio is 1:(0.7-1.5).The melting time of the step B is 1-5min.
As an improvement, the step C initiators are the 0.1%-2% of makrolon weight.
In contrast experiment, inventor will can trigger infection and inflammation, the stronger Pseudomonas aeruginosa of drug resistance and golden yellow Portugal Grape coccus is transplanted to the eye speculum of this polymer coating and common eye speculum respectively.The test carried out after after a while shows Show, the pathogen residual quantity of new polymers coating surface just corresponds to the thousands of to several of common medical plastic surface bacteria quantity Hundred a ten thousandths.
Brief description of the drawings
Fig. 1 is the structural representation of the present invention;
The observation figure of opposite side of the present invention on Fig. 2;
Marked in figure:1- support frames, 2- jig arm, 3- hook portions, 5- head rods, 6- center-poles, 7- clamping devices, 701- are fixed Pipe, 702- handles, the connecting rods of 703- second, 704- articulated joints, 8- sebific ducts.
Embodiment
Below in conjunction with the accompanying drawings, the present invention is described in detail.
In order to make the purpose , technical scheme and advantage of the present invention be clearer, it is right below in conjunction with drawings and Examples The present invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, and It is not used in the restriction present invention.
Specific embodiment 1:A kind of medical eye speculum, including support frame 1, clamping device 7, jig arm 2, the one of described jig arm End and support frame 1 are be hinged, and the other end of described jig arm is fixedly connected with hook portion 3, and the centre of support frame is provided with passage, center-pole 6 pass through passage, and the end of center-pole is hinged with head rod 5, and the second connecting rod is two, and one end of head rod is with Core bar is hinged, and the other end and jig arm are hinged, and the top of center-pole fills for the clamping that control centre's bar relative support frame moves forward and backward Put 7;
Described clamping device includes the fixing pipe 701 being fixedly connected with support frame, and the end of described fixing pipe is hinged with handle Hand 702, described handle are two, and described handle is the grip structure of pliers, and center-pole passes through fixing pipe 701, center-pole End be hinged with the second connecting rod 703 two, one end of the second connecting rod and the end of center-pole are hinged, the other end and handle 703 is be hinged, grip handle, and the second connecting rod control centre bar controls the contraction of jig arm toward post-tensioning, reduces between hook portion Distance, opens handle, center-pole reach, and jig arm is opened.Described center-pole and the connection end of handle are provided with articulated joint 704, institute The articulated joint stated is hinged with the second connecting rod 703, the second described articulated joint and center-pole as threaded connection, while fixing pipe can Rotated with relative support frame, rotate articulated joint, articulated joint can move along the axial direction of center-pole, can adjust clamping dress The elasticity put.
Described support frame center is provided with passage, and vias inner walls are screw thread, and fixing pipe is connected by passage and support frame screw thread Connect, articulated joint can do radial rotating with respect to center-pole, rotate fixing pipe, and fixing pipe can axially move along the passage of support frame It is dynamic;One of them of described jig arm is provided with the transfusion road connected with hook portion, and decoction is transported to hook portion simultaneously by described transfusion road And eyes are moistened, the transfusion road end in jig arm connects the sebific duct 8 for providing decoction.
Specific embodiment 2:The hook surface for being eye speculum with the distinctive points of embodiment 1 is provided with one layer of polymeric coating, Described polymer coating is a kind of makrolon multi-monomer grafting polymer, it is characterised in that described grafted monomers bag Include containing dimethyl (2- pyridine radicals) vinyl silanes and acrylonitrile monemer.
Described polymer and grafted monomers parts by weight of raw materials is as follows:100 parts of makrolon, dimethyl (2- pyridine radicals) second 5 parts of alkenyl silanes monomer, 20 parts of acrylonitrile monemer.
The preparation method of polymer coating is as follows:
Step A:Unsaturated silane, acrylonitrile are uniformly mixed;
Step B:Makrolon is melted in rheometer, melting time 5min;
Step C:Mixture and initiator after step A are added in rheometer, and initiator is the 0.1% of makrolon weight, React 5 min;
Described initiator is the mixture of benzoyl peroxide and cumyl peroxide, mol ratio 1:0.7.
The eye speculum of embodiment 1 and embodiment 1 is subjected to contrast discovery, the bacterium residual of embodiment 2 is the ten thousand of embodiment 1 / bis-.

Claims (7)

1. a kind of medical eye speculum antimicrobial coating, it is characterised in that antimicrobial coating is a kind of polymer coating, described polymerization Thing coating is a kind of makrolon multi-monomer grafting polymer, and described grafted monomers include containing phenyl ring or pyridine ring insatiable hunger With silane and acrylonitrile monemer.
2. medical eye speculum antimicrobial coating according to claim 1, it is characterised in that described unsaturated silane monomer choosing From:Triple phenoxyl vinyl silanes, 3- chloropropyl dimethylvinylsiloxies base silane, triphenyl vinyl silane, 3,5-dimethylphenyl second Alkenyl silanes, dimethyl (2- pyridine radicals) vinyl silanes.
3. medical eye speculum antimicrobial coating according to claim 2, it is characterised in that described polymer and grafted monomers Parts by weight of raw materials is as follows:100 parts of makrolon, unsaturated silane monomer 5-20 parts, acrylonitrile monemer 5-20 parts.
4. medical eye speculum antimicrobial coating according to claim 3, it is characterised in that the preparation of described polymer coating Method is as follows:
Step A:Unsaturated silane, acrylonitrile are uniformly mixed;
Step B:Makrolon is melted in rheometer;
Step C:Mixture and initiator after step A are added in rheometer, react 5 min -10min.
5. medical eye speculum antimicrobial coating according to claim 4, it is characterised in that described initiator is selected from peroxidating Benzoyl, lauroyl peroxide, isopropyl benzene hydroperoxide, TBHP, cumyl peroxide.
6. medical eye speculum antimicrobial coating according to claim 5, it is characterised in that described initiator is benzoyl peroxide The mixture of formyl and cumyl peroxide, mol ratio 1:(0.7-1.5).
7. medical eye speculum antimicrobial coating according to claim 6, it is characterised in that the melting time of the step B is 1-5min。
CN201711222345.1A 2017-11-29 2017-11-29 A kind of medical eye speculum antimicrobial coating Withdrawn CN107890587A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108577908A (en) * 2018-05-15 2018-09-28 温州医科大学附属第医院 A kind of anus drag-hook and preparation method thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4336358A (en) * 1979-11-28 1982-06-22 Bayer Aktiengesellschaft Organopolysiloxane-urethane-vinyl graft copolymers
CN104136500A (en) * 2012-01-04 2014-11-05 莫门蒂夫性能材料股份有限公司 Polymer composites of silicone ionomers
CN105111710A (en) * 2015-09-22 2015-12-02 陆思烨 Bus and subway handle with antibacterial and healthcare function and preparation method thereof
CN105593254A (en) * 2013-09-30 2016-05-18 Dic株式会社 Polycarbonate-modified acrylic resin, coating, and plastic molding coated with said coating
CN106632864A (en) * 2016-12-05 2017-05-10 彭州市运达知识产权服务有限公司 HDPE multi-monomer graft polymer and preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4336358A (en) * 1979-11-28 1982-06-22 Bayer Aktiengesellschaft Organopolysiloxane-urethane-vinyl graft copolymers
CN104136500A (en) * 2012-01-04 2014-11-05 莫门蒂夫性能材料股份有限公司 Polymer composites of silicone ionomers
CN105593254A (en) * 2013-09-30 2016-05-18 Dic株式会社 Polycarbonate-modified acrylic resin, coating, and plastic molding coated with said coating
CN105111710A (en) * 2015-09-22 2015-12-02 陆思烨 Bus and subway handle with antibacterial and healthcare function and preparation method thereof
CN106632864A (en) * 2016-12-05 2017-05-10 彭州市运达知识产权服务有限公司 HDPE multi-monomer graft polymer and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108577908A (en) * 2018-05-15 2018-09-28 温州医科大学附属第医院 A kind of anus drag-hook and preparation method thereof

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Application publication date: 20180410