CN107890371B - Nuclear magnetic microwave ablation needle positioning system and positioning method thereof - Google Patents

Nuclear magnetic microwave ablation needle positioning system and positioning method thereof Download PDF

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CN107890371B
CN107890371B CN201711137792.7A CN201711137792A CN107890371B CN 107890371 B CN107890371 B CN 107890371B CN 201711137792 A CN201711137792 A CN 201711137792A CN 107890371 B CN107890371 B CN 107890371B
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microwave ablation
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CN107890371A (en
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杨斌
孙良俊
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Nanjing Yigao Medical Technology Co.,Ltd.
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Nanjing Eco Microwave System Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37Surgical systems with images on a monitor during operation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37Surgical systems with images on a monitor during operation
    • A61B2090/374NMR or MRI

Abstract

The invention discloses a nuclear magnetic microwave ablation needle positioning system, which comprises a signal receiving module, a signal processing module and a signal processing module, wherein the signal receiving module is used for receiving nuclear magnetic signals; the radio frequency noise processing module is used for separating and inhibiting radio frequency noise interference in the received nuclear magnetic signals; the magnetic susceptibility artifact processing module is used for eliminating the magnetic susceptibility artifact in the received nuclear magnetic signals; the truncation artifact processing module is used for eliminating truncation artifacts in the received nuclear magnetic signals; and the identification module is used for positioning the microwave ablation needle by identifying the position of the positioning marker in the microwave ablation needle. The method can improve the defects of the prior art, can effectively eliminate the artifact interference of the microwave ablation needle in the nuclear magnetic image, and simultaneously reduces the distortion degree of the image.

Description

Nuclear magnetic microwave ablation needle positioning system and positioning method thereof
Technical Field
The invention relates to a tumor minimally invasive treatment device, in particular to a nuclear magnetic microwave ablation needle positioning system and a positioning method thereof.
Background
The current minimally invasive interventional ablation tumor treatment means comprise minimally invasive treatment such as radio frequency, argon-helium knife and the like. The commonly used imaging devices are B-ultrasound, CT, and nuclear magnetic. In the clinic of tumor treatment, each has characteristics and advantages, but all have limitations and defects. Radio frequency can achieve better effect on early-stage smaller tumors, but can not completely inactivate the tumors of a patient with a slightly large tumor; the argon-helium knife has better comfort for patients in the process of tumor treatment, can relieve the pain of the patients in the treatment process, but has the risk of relapse of the treatment area at the later stage. Therefore, it is desired to find a method for treating tumor, which can kill cancer cells rapidly and effectively, protect normal tissues as much as possible and prevent recurrence. In recent years, the heteroplasmy protuberance of the minimally invasive treatment intervention of the microwave tumor attracts attention. Minimally invasive therapy guided under nuclear magnetic imaging is now internationally listed as a very promising area for tumor therapy (three-dimensional real-time dynamic imaging). The existing nuclear magnetic microwave ablation needle has large artifacts developed under a magnetic field, and the puncture position is influenced in the operation process. Although there are various methods for suppressing and eliminating artifacts in the prior art, all of them are to eliminate a specific artifact, and the distortion of an image is greatly increased after the same image is processed by adopting a plurality of methods for eliminating artifacts. Because the microwave ablation needle mainly generates radio frequency noise, magnetic susceptibility artifacts and truncation artifacts in nuclear magnetic images, no method for eliminating the artifacts of the microwave ablation needle exists in the prior art, so that the image distortion degree after the artifacts are eliminated is reduced.
Disclosure of Invention
The invention aims to provide a nuclear magnetic microwave ablation needle positioning system and a positioning method thereof, which can overcome the defects of the prior art, effectively eliminate artifact interference of a microwave ablation needle in a nuclear magnetic image and reduce the distortion of the image.
In order to solve the technical problems, the technical scheme adopted by the invention is as follows.
A nuclear magnetic microwave ablation needle positioning system comprises,
the signal receiving module is used for receiving the nuclear magnetic signals;
the radio frequency noise processing module is used for separating and inhibiting radio frequency noise interference in the received nuclear magnetic signals;
the magnetic susceptibility artifact processing module is used for eliminating the magnetic susceptibility artifact in the received nuclear magnetic signals;
the truncation artifact processing module is used for eliminating truncation artifacts in the received nuclear magnetic signals;
and the identification module is used for positioning the microwave ablation needle by identifying the position of the positioning marker in the microwave ablation needle.
The positioning method of the nuclear magnetic microwave ablation needle positioning system comprises the following steps:
A. performing nuclear magnetic imaging on the microwave ablation needle, and receiving an echo of a nuclear magnetic signal by a signal receiving module to generate an image;
B. the radio frequency noise processing module separates and inhibits the radio frequency noise in the image generated by the signal receiving module;
C. the magnetic susceptibility artifact processing module eliminates the magnetic susceptibility artifact in the image processed by the radio frequency noise processing module;
D. the truncation artifact processing module eliminates the truncation artifact of the image processed by the magnetic susceptibility artifact processing module;
E. and D, positioning the microwave ablation needle by the identification module according to the image processed in the step D.
Preferably, in the step B, the separating and suppressing the radio frequency noise includes the steps of,
b1, selecting several mark areas on the image, recording the state attribute vector S = [ S ] of each mark area1,s2,s3,,s4]Whereins1As a phase attribute, s2As a frequency attribute, s3As a gray attribute, s4Is a location attribute;
b2, calculating the comprehensive fluctuation value J of the state attribute vector of each mark area,
Figure DEST_PATH_IMAGE001
Figure 377193DEST_PATH_IMAGE002
Figure DEST_PATH_IMAGE003
Figure 398370DEST_PATH_IMAGE004
b3, calculating the credibility R of the marking area according to the comprehensive fluctuation value J of the state attribute vector of the marking area,
Figure DEST_PATH_IMAGE005
wherein the content of the first and second substances,
Figure 446091DEST_PATH_IMAGE006
Figure DEST_PATH_IMAGE007
is a weighting coefficient;
b4, comparing the mark areas with the maximum reliability and the minimum reliability to obtain an image deviation amount, traversing the image deviation amount and the phase codes of each frequency band in each mark area, and deleting the frequency band data in the image if the phase codes of the traversing image deviation amount in a certain frequency band are the same as the phase codes of all the mark areas in the frequency band.
Preferably, the elimination of susceptibility artifacts in step C comprises the steps of,
c1, traversing the image, and determining a magnetic susceptibility artifact area according to the gradient change of the image gray level;
c2, replacing the pixel blocks at the inner edge of the magnetic susceptibility artifact area by using the pixel blocks at the outer edge of the magnetic susceptibility artifact area, performing linear fitting on the gray value of the replacement area after replacement, and adjusting the gray value at the corresponding position according to the fitting result; the replacement process is circularly carried out until the susceptibility artifact area is completely replaced;
c3, fine-tuning the image gray scale processed in the step C2 to make the gradient change direction of the image gray scale before and after the step C2.
Preferably, the elimination of truncation artifacts in step D comprises the steps of,
d1, carrying out Fourier decomposition on the image processed in the step C, and deleting image components with step changes;
d2, if the frequency band of the image component deleted in the step D1 is adjacent to the data frequency band deleted in the step B4, performing Fourier decomposition again on the image data deleted in the step D1 and the step B4, reserving the linearly related data component, and supplementing the data component into the image component processed in the step D1;
d3, carrying out Fourier inversion on each image component processed by the D2 to obtain an image with the artifact removed.
Adopt the beneficial effect that above-mentioned technical scheme brought to lie in: the invention carries out corresponding design aiming at radio frequency noise, magnetic susceptibility artifacts and truncation artifacts mainly generated by a microwave ablation needle in nuclear magnetic images. By establishing a credibility calculation method of the image areas, the frequency bands of the radio frequency noise are distinguished by utilizing the self difference between the image areas, and the radio frequency noise is eliminated with pertinence. And for the magnetic susceptibility artifact, the artifact is eliminated by using an image replacement mode, so that image distortion caused by excessively deleting image information data is avoided. By further processing the replacement image during the replacement process, new artifact areas are avoided during the replacement process. For the truncation artifact, the typical step change characteristics brought by the truncation artifact are searched after Fourier decomposition, so that the truncation artifact is separated and eliminated. In order to reduce the loss of image information in the artifact elimination process, the integrity of the image information is maintained to the maximum extent through comparison and analysis with the corresponding frequency band in the radio frequency noise processing process, so that the image distortion degree is reduced.
Drawings
FIG. 1 is a schematic diagram of one embodiment of the present invention.
In the figure: 1. a signal receiving module; 2. a radio frequency noise processing module; 3. a susceptibility artifact processing module; 4. a truncation artifact processing module; 5. and identifying the module.
Detailed Description
The standard parts used in the invention can be purchased from the market, the special-shaped parts can be customized according to the description and the description of the attached drawings, and the specific connection mode of each part adopts the conventional means of mature bolts, rivets, welding, sticking and the like in the prior art, and the detailed description is not repeated.
Referring to fig. 1, one embodiment of the present invention includes,
the signal receiving module 1 is used for receiving nuclear magnetic signals;
the radio frequency noise processing module 2 is used for separating and suppressing radio frequency noise interference in the received nuclear magnetic signals;
the magnetic susceptibility artifact processing module 3 is used for eliminating the magnetic susceptibility artifact in the received nuclear magnetic signals;
the truncation artifact processing module 4 is used for eliminating truncation artifacts in the received nuclear magnetic signals;
and the identification module 5 is used for positioning the microwave ablation needle by identifying the position of the positioning marker 6 in the microwave ablation needle.
The positioning method of the nuclear magnetic microwave ablation needle positioning system comprises the following steps:
A. performing nuclear magnetic imaging on the microwave ablation needle, and receiving the echo of the nuclear magnetic signal by the signal receiving module 1 and generating an image;
B. the radio frequency noise processing module 2 separates and suppresses the radio frequency noise in the image generated by the signal receiving module 1;
C. the magnetic susceptibility artifact processing module 3 eliminates the magnetic susceptibility artifact in the image processed by the radio frequency noise processing module 2;
D. the truncation artifact processing module 4 eliminates the truncation artifact of the image processed by the magnetic susceptibility artifact processing module;
E. and D, the identification module 5 carries out microwave ablation needle positioning according to the image processed in the step D.
In the step B, the radio frequency noise separation and suppression comprises the following steps,
b1, selecting several mark areas on the image, recording the state attribute vector S = [ S ] of each mark area1,s2,s3,,s4]Wherein s is1As a phase attribute, s2As a frequency attribute, s3As a gray attribute, s4Is a location attribute;
b2, calculating the comprehensive fluctuation value J of the state attribute vector of each mark area,
Figure 417108DEST_PATH_IMAGE001
Figure 92940DEST_PATH_IMAGE002
Figure 409652DEST_PATH_IMAGE003
Figure 210249DEST_PATH_IMAGE004
b3, calculating the credibility R of the marking area according to the comprehensive fluctuation value J of the state attribute vector of the marking area,
Figure 513186DEST_PATH_IMAGE005
wherein the content of the first and second substances,
Figure 775015DEST_PATH_IMAGE006
Figure 262628DEST_PATH_IMAGE007
is a weighting coefficient;
b4, comparing the mark areas with the maximum reliability and the minimum reliability to obtain an image deviation amount, traversing the image deviation amount and the phase codes of each frequency band in each mark area, and deleting the frequency band data in the image if the phase codes of the traversing image deviation amount in a certain frequency band are the same as the phase codes of all the mark areas in the frequency band.
In step C, the elimination of susceptibility artifacts includes the steps of,
c1, traversing the image, and determining a magnetic susceptibility artifact area according to the gradient change of the image gray level;
c2, replacing the pixel blocks at the inner edge of the magnetic susceptibility artifact area by using the pixel blocks at the outer edge of the magnetic susceptibility artifact area, performing linear fitting on the gray value of the replacement area after replacement, and adjusting the gray value at the corresponding position according to the fitting result; the replacement process is circularly carried out until the susceptibility artifact area is completely replaced;
c3, fine-tuning the image gray scale processed in the step C2 to make the gradient change direction of the image gray scale before and after the step C2.
In the linear fitting process, for the pixel blocks which are not on the fitting result, the weighted average value of the original gray scale of the pixel blocks and the corresponding gray scale on the fitting result is used for substitution, and the weighting coefficient of the original gray scale of the pixel blocks is in direct proportion to the square of the difference value of the original gray scale of the pixel blocks and the corresponding gray scale on the fitting result.
In step D, the elimination of truncation artifacts includes the steps of,
d1, carrying out Fourier decomposition on the image processed in the step C, and deleting image components with step changes;
d2, if the frequency band of the image component deleted in the step D1 is adjacent to the data frequency band deleted in the step B4, performing Fourier decomposition again on the image data deleted in the step D1 and the step B4, reserving the linearly related data component, and supplementing the data component into the image component processed in the step D1;
d3, carrying out Fourier inversion on each image component processed by the D2 to obtain an image with the artifact removed.
When the relevant data component is supplemented in step D2, the step change amplitude of the region where the step change occurs is weakened, so that the step change amplitude is reduced to 50% of the original step change amplitude.
The method and the device perform targeted image processing aiming at the artifact interference generated by the microwave ablation needle in the nuclear magnetic image, reduce the distortion degree of the image while eliminating the artifact interference, and are beneficial to accurately positioning the microwave ablation needle through the nuclear magnetic image by medical personnel.
In the description of the present invention, it is to be understood that the terms "longitudinal", "lateral", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on those shown in the drawings, are merely for convenience of description of the present invention, and do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present invention.
The foregoing shows and describes the general principles and broad features of the present invention and advantages thereof. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (3)

1. A positioning method of a nuclear magnetic microwave ablation needle positioning system comprises the following steps,
the signal receiving module (1) is used for receiving nuclear magnetic signals;
the radio frequency noise processing module (2) is used for separating and inhibiting radio frequency noise interference in the received nuclear magnetic signals;
the magnetic susceptibility artifact processing module (3) is used for eliminating the magnetic susceptibility artifact in the received nuclear magnetic signals;
a truncation artifact processing module (4) for eliminating truncation artifacts in the received nuclear magnetic signals;
an identification module (5) for positioning the microwave ablation needle by identifying the position of the positioning marker (6) in the microwave ablation needle
The method is characterized by comprising the following steps:
A. performing nuclear magnetic imaging on the microwave ablation needle, and receiving the echo of the nuclear magnetic signal by the signal receiving module (1) and generating an image;
B. the radio frequency noise processing module (2) separates and suppresses the radio frequency noise in the image generated by the signal receiving module (1);
the radio frequency noise separation and suppression includes the following steps,
b1, selecting several mark areas on the image, recording the state attribute vector S = [ S ] of each mark area1,s2,s3,s4]Wherein s is1As a phase attribute, s2As a frequency attribute, s3As a gray attribute, s4Is a location attribute;
b2, calculating the comprehensive fluctuation value J of the state attribute vector of each mark area,
Figure DEST_PATH_IMAGE002
Figure DEST_PATH_IMAGE004
Figure DEST_PATH_IMAGE006
Figure DEST_PATH_IMAGE008
b3, calculating the credibility R of the marking area according to the comprehensive fluctuation value J of the state attribute vector of the marking area,
Figure DEST_PATH_IMAGE010
wherein the content of the first and second substances,
Figure DEST_PATH_IMAGE012
Figure DEST_PATH_IMAGE014
is a weighting coefficient;
b4, comparing the mark areas with the maximum reliability and the minimum reliability to obtain an image deviation amount, traversing the image deviation amount and phase codes of each frequency band in each mark area, and deleting the frequency band data in the image if the phase codes of the traversing image deviation amount in a certain frequency band are the same as the phase codes of all the mark areas in the frequency band;
C. the magnetic susceptibility artifact processing module (3) eliminates the magnetic susceptibility artifact in the image processed by the radio frequency noise processing module (2);
D. the truncation artifact processing module (4) eliminates the truncation artifact of the image processed by the magnetic susceptibility artifact processing module;
E. and D, positioning the microwave ablation needle by the identification module (5) according to the image processed in the step D.
2. The positioning method of the nuclear magnetic microwave ablation needle positioning system according to claim 1, characterized in that: in step C, the elimination of susceptibility artifacts includes the steps of,
c1, traversing the image, and determining a magnetic susceptibility artifact area according to the gradient change of the image gray level;
c2, replacing the pixel blocks at the inner edge of the magnetic susceptibility artifact area by using the pixel blocks at the outer edge of the magnetic susceptibility artifact area, performing linear fitting on the gray value of the replacement area after replacement, and adjusting the gray value at the corresponding position according to the fitting result; the replacement process is circularly carried out until the susceptibility artifact area is completely replaced;
c3, fine-tuning the image gray scale processed in the step C2 to make the gradient change direction of the image gray scale before and after the step C2.
3. The positioning method of the nuclear magnetic microwave ablation needle positioning system according to claim 2, characterized in that: in step D, the elimination of truncation artifacts includes the steps of,
d1, carrying out Fourier decomposition on the image processed in the step C, and deleting image components with step changes;
d2, if the frequency band of the image component deleted in the step D1 is adjacent to the data frequency band deleted in the step B4, performing Fourier decomposition again on the image data deleted in the step D1 and the step B4, reserving the linearly related data component, and supplementing the data component into the image component processed in the step D1;
d3, carrying out Fourier inversion on each image component processed by the D2 to obtain an image with the artifact removed.
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