CN107890371A - A kind of nuclear-magnetism microwave melt needle alignment system and its localization method - Google Patents
A kind of nuclear-magnetism microwave melt needle alignment system and its localization method Download PDFInfo
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- CN107890371A CN107890371A CN201711137792.7A CN201711137792A CN107890371A CN 107890371 A CN107890371 A CN 107890371A CN 201711137792 A CN201711137792 A CN 201711137792A CN 107890371 A CN107890371 A CN 107890371A
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- A61B90/37—Surgical systems with images on a monitor during operation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/36—Image-producing devices or illumination devices not otherwise provided for
- A61B90/37—Surgical systems with images on a monitor during operation
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Abstract
The invention discloses a kind of nuclear-magnetism microwave melt needle alignment system, including signal receiving module, for receiving nuclear magnetic signal；Radio noise processing module, for the RF noise jamming in reception nuclear magnetic signal to be separated and suppressed；Magnetic susceptibility artifact processing module, for being eliminated to receiving the magnetic susceptibility artifact in nuclear magnetic signal；Gibbs artifact processing module, for being eliminated to receiving the gibbs artifact in nuclear magnetic signal；Identification module, by identifying that the position of location marker in microwave melt needle positions to microwave melt needle.The present invention can improve the deficiencies in the prior art, can effectively eliminate artifact interference of the microwave melt needle in nuclear-magnetism image, while reduce the distortion factor of image.
Description
Technical field
The present invention relates to a kind of tumor micro-wound therapeutic system, especially a kind of nuclear-magnetism microwave melt needle alignment system and its fixed
Position method.
Background technology
Minimally-invasive treatments such as current minimally invasive intervention ablation oncotherapy means include, radio frequency, argon helium knife etc..Conventional image
Equipment is B ultrasound, CT, nuclear-magnetism.In the clinic of oncotherapy, respectively there are feature and advantage, but also have its limitation and defect.Penetrate
Frequency can obtain better effects for the relatively little tumour of early stage, but often can not thoroughly be inactivated for any big tumor patient swollen
Knurl；For argon helium knife during oncotherapy, patient comfort is preferable, can mitigate the pain of patient in therapeutic process, but rear
Phase can deposit the risk for the treatment of region recurrence.So people look forward to finding always one kind can fast and effective killing cancer cell, and can
The method for protecting normal structure and treatment tumour uneasy to recur as far as possible.In recent years, the minimally invasive treatment PCI of microwave tumour is different
Army's projection, it is noticeable.The minimally-invasive treatment guided under present magnetic resonance imaging has been listed in before oncotherapy has very much in the world
The field of scape（Three-dimensional dynamic in real time is developed）.The artifact that existing nuclear-magnetism microwave melt needle develops under magnetic field is larger, surgical procedure
In, influence the position punctured.Although also having the various suppression for artifact and removing method in the prior art, it is pin
Processing for removing is carried out to a certain specific artifact, after being handled for same image using the method for a variety of elimination artifacts, figure
The distortion factor of picture can greatly increase.Because microwave melt needle mainly occurs that radio noise, magnetic susceptibility are pseudo- in magnetic resonance imaging
Shadow and gibbs artifact, also eliminated in the prior art without a removing method specifically for microwave melt needle artifact with reducing
The image fault degree of pseudo- movie queen.
The content of the invention
The technical problem to be solved in the present invention is to provide a kind of nuclear-magnetism microwave melt needle alignment system and its localization method, can solve
Certainly the deficiencies in the prior art, artifact interference of the microwave melt needle in nuclear-magnetism image can be effectively eliminated, while reduce image
The distortion factor.
In order to solve the above technical problems, the technical solution used in the present invention is as follows.
A kind of nuclear-magnetism microwave melt needle alignment system, including,
Signal receiving module, for receiving nuclear magnetic signal；
Radio noise processing module, for the RF noise jamming in reception nuclear magnetic signal to be separated and suppressed；
Magnetic susceptibility artifact processing module, for being eliminated to receiving the magnetic susceptibility artifact in nuclear magnetic signal；
Gibbs artifact processing module, for being eliminated to receiving the gibbs artifact in nuclear magnetic signal；
Identification module, by identifying that the position of location marker in microwave melt needle positions to microwave melt needle.
A kind of localization method of above-mentioned nuclear-magnetism microwave melt needle alignment system, comprises the following steps：
A, NMR imaging is carried out to microwave melt needle, signal receiving module receives the echo of nuclear magnetic signal and generates image；
B, the radio noise that radio noise processing module is generated in image to signal receiving module is separated and suppressed；
C, magnetic susceptibility artifact processing module disappears to the magnetic susceptibility artifact in the image by the processing of radio noise processing module
Remove；
D, gibbs artifact processing module eliminates to the gibbs artifact of the image by the processing of magnetic susceptibility artifact processing module；
E, identification module carries out microwave melt needle positioning according to the image after step D processing.
Preferably, in step B, radio noise is separated and suppression comprises the following steps,
B1, several optional marked regions on image, record status attribute vector S=[s of each marked region1, s2, s3,,
s4], wherein s1For phase attributes, s2For frequency attribute, s3For gray scale attribute, s4For position attribution；
B2, the vectorial synthesis undulating value J of the status attribute of each marked region is calculated,
,
,
,
；
B3, the confidence level R according to the vectorial synthesis undulating value J calculating marked regions of the status attribute of marked region,
Wherein,~For weight coefficient；
B4, maximum by confidence level and the marked region of confidence level minimum is contrasted, and obtains image deviations amount, travels through image deviations
The phase code of amount and each frequency range in each marked region, if the traversing graph in a certain frequency range is as departure phase code and this frequency
All marked region phase code all sames in section, then deleted this frequency range data in image.
Preferably, in step C, elimination is carried out to magnetic susceptibility artifact and comprised the following steps,
C1, traversing graph picture, magnetic susceptibility artifact region is determined according to the graded of gradation of image；
C2, use block of pixels progress of the block of pixels at magnetic susceptibility artifact areas outside edge to magnetic susceptibility artifact area inside edge
Replace, linear fit is carried out to the gray value for replacing region after replacement, and the gray value of correspondence position is adjusted according to fitting result；
Above-mentioned replacement process is circulated and carried out, until magnetic susceptibility artifact region is replaced completely；
C3, the gradation of image after step C2 processing is finely adjusted, makes the gradient of the gradation of images of step C2 before and after the processing
Change direction is identical.
Preferably, in step D, elimination is carried out to gibbs artifact and comprised the following steps,
D1, Fourier decomposition is carried out to the image by step C processing, delete the picture content with Spline smoothing；
If the frequency range where the picture content deleted in D2, step D1 is adjacent with the data band deleted in step B4, to step
The view data deleted in rapid D1 and step B4 carries out Fourier decomposition again, and the data component of linear correlation is protected
Stay, fill into the picture content after step D1 processing；
D3, by after D2 is handled each picture content carry out Fourier inversion, the image for the pseudo- movie queen that is eliminated.
It is using beneficial effect caused by above-mentioned technical proposal：The present invention is for microwave melt needle in nuclear-magnetism image
Radio noise, magnetic susceptibility artifact and gibbs artifact caused by main, have carried out corresponding design.Can by establish image-region
Reliability computational methods, using the residing frequency range of itself Differential discrimination radio noise between image-region, and have and be directed to
The elimination of property.For magnetic susceptibility artifact, the mode replaced using image is eliminated, and is avoided and is excessively deleted image information data
Caused image fault.By the further processing to replacing image in replacement process, avoid occurring newly in replacement process
Artifact region.For gibbs artifact, the typical Spline smoothing feature brought by finding gibbs artifact after Fourier decomposition, come
Gibbs artifact is carried out respectively and eliminated.In order to reduce loss for image information during artifact eliminates, by with radio frequency
The contrast and analysis of corresponding frequency band, have been maximally maintained the integrity degree of image information during noise processed, so as to reduce
Image fault degree.
Brief description of the drawings
Fig. 1 is the schematic diagram of an embodiment of the invention.
In figure：1st, signal receiving module；2nd, radio noise processing module；3rd, magnetic susceptibility artifact processing module；4th, puppet is blocked
Shadow processing module；5th, identification module.
Embodiment
The standardized element used in the present invention can commercially, and shaped piece is according to specification and accompanying drawing
Record can carry out customized, and the specific connected mode of each part is using bolt ripe in the prior art, rivet, weldering
The conventional meanses such as connect, paste, will not be described in detail herein.
Reference picture 1, an embodiment of the invention include,
Signal receiving module 1, for receiving nuclear magnetic signal；
Radio noise processing module 2, for the RF noise jamming in reception nuclear magnetic signal to be separated and suppressed；
Magnetic susceptibility artifact processing module 3, for being eliminated to receiving the magnetic susceptibility artifact in nuclear magnetic signal；
Gibbs artifact processing module 4, for being eliminated to receiving the gibbs artifact in nuclear magnetic signal；
Identification module 5, by identifying that the position of location marker 6 in microwave melt needle positions to microwave melt needle.
A kind of localization method of above-mentioned nuclear-magnetism microwave melt needle alignment system, comprises the following steps：
A, NMR imaging is carried out to microwave melt needle, signal receiving module 1 receives the echo of nuclear magnetic signal and generates image；
B, the radio noise that radio noise processing module 2 is generated in image to signal receiving module 1 is separated and suppressed；
C, magnetic susceptibility artifact processing module 3 is carried out to the magnetic susceptibility artifact in the image by the processing of radio noise processing module 2
Eliminate；
D, gibbs artifact processing module 4 eliminates to the gibbs artifact of the image by the processing of magnetic susceptibility artifact processing module；
E, identification module 5 carries out microwave melt needle positioning according to the image after step D processing.
In step B, radio noise is separated and suppression comprises the following steps,
B1, several optional marked regions on image, record status attribute vector S=[s of each marked region1, s2, s3,,
s4], wherein s1For phase attributes, s2For frequency attribute, s3For gray scale attribute, s4For position attribution；
B2, the vectorial synthesis undulating value J of the status attribute of each marked region is calculated,
,
,
,
；
B3, the confidence level R according to the vectorial synthesis undulating value J calculating marked regions of the status attribute of marked region,
Wherein,~For weight coefficient；
B4, maximum by confidence level and the marked region of confidence level minimum is contrasted, and obtains image deviations amount, travels through image deviations
The phase code of amount and each frequency range in each marked region, if the traversing graph in a certain frequency range is as departure phase code and this frequency
All marked region phase code all sames in section, then deleted this frequency range data in image.
In step C, elimination is carried out to magnetic susceptibility artifact and comprised the following steps,
C1, traversing graph picture, magnetic susceptibility artifact region is determined according to the graded of gradation of image；
C2, use block of pixels progress of the block of pixels at magnetic susceptibility artifact areas outside edge to magnetic susceptibility artifact area inside edge
Replace, linear fit is carried out to the gray value for replacing region after replacement, and the gray value of correspondence position is adjusted according to fitting result；
Above-mentioned replacement process is circulated and carried out, until magnetic susceptibility artifact region is replaced completely；
C3, the gradation of image after step C2 processing is finely adjusted, makes the gradient of the gradation of images of step C2 before and after the processing
Change direction is identical.
Wherein, in linear fitting procedure, for the block of pixels not on fitting result, block of pixels former ash degree and plan are used
The weighted average for closing corresponding grey scale in result is substituted, weight coefficient and block of pixels former ash degree and the plan of block of pixels former ash degree
Close the square directly proportional of the difference of corresponding grey scale in result.
In step D, elimination is carried out to gibbs artifact and comprised the following steps,
D1, Fourier decomposition is carried out to the image by step C processing, delete the picture content with Spline smoothing；
If the frequency range where the picture content deleted in D2, step D1 is adjacent with the data band deleted in step B4, to step
The view data deleted in rapid D1 and step B4 carries out Fourier decomposition again, and the data component of linear correlation is protected
Stay, fill into the picture content after step D1 processing；
D3, by after D2 is handled each picture content carry out Fourier inversion, the image for the pseudo- movie queen that is eliminated.
Wherein, when step D2 fills into related data component, the Spline smoothing amplitude that step-graded region is produced to it is entered
Row reduction, make its Spline smoothing amplitude reduction for the 50% of former Spline smoothing amplitude.
The present invention caused artifact interference in nuclear-magnetism image for microwave melt needle, has carried out having targetedly image
Processing, while artifact interference is eliminated, the distortion factor of image is reduced, is advantageous to medical worker by nuclear-magnetism image to microwave
Ablation needle is accurately positioned.
In the description of the invention, it is to be understood that term " longitudinal direction ", " transverse direction ", " on ", " under ", "front", "rear",
The orientation or position relationship of the instruction such as "left", "right", " vertical ", " level ", " top ", " bottom ", " interior ", " outer " is based on accompanying drawing institutes
The orientation or position relationship shown, the description present invention is for only for ease of, rather than the device or element of instruction or hint meaning must
There must be specific orientation, with specific azimuth configuration and operation, therefore be not considered as limiting the invention.
The general principle and principal character and advantages of the present invention of the present invention has been shown and described above.The technology of the industry
Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the simply explanation described in above-described embodiment and specification is originally
The principle of invention, without departing from the spirit and scope of the present invention, various changes and modifications of the present invention are possible, these changes
Change and improvement all fall within the protetion scope of the claimed invention.The claimed scope of the invention by appended claims and its
Equivalent thereof.
Claims (5)
- A kind of 1. nuclear-magnetism microwave melt needle alignment system, it is characterised in that：Including,Signal receiving module（1）, for receiving nuclear magnetic signal；Radio noise processing module（2）, for the RF noise jamming in reception nuclear magnetic signal to be separated and suppressed；Magnetic susceptibility artifact processing module（3）, for being eliminated to receiving the magnetic susceptibility artifact in nuclear magnetic signal；Gibbs artifact processing module（4）, for being eliminated to receiving the gibbs artifact in nuclear magnetic signal；Identification module（5）, by identifying location marker in microwave melt needle（6）Position microwave melt needle is positioned.
- 2. the localization method of the nuclear-magnetism microwave melt needle alignment system described in a kind of claim 1, it is characterised in that including following Step：A, NMR imaging, signal receiving module are carried out to microwave melt needle（1）Receive the echo of nuclear magnetic signal and generate image；B, radio noise processing module（2）To signal receiving module（1）Radio noise in generation image is separated and suppressed；C, magnetic susceptibility artifact processing module（3）To passing through radio noise processing module（2）Magnetic susceptibility artifact in the image of processing Eliminated；D, gibbs artifact processing module（4）The gibbs artifact of image by the processing of magnetic susceptibility artifact processing module is disappeared Remove；E, identification module（5）Microwave melt needle positioning is carried out according to the image after step D processing.
- 3. the localization method of nuclear-magnetism microwave melt needle alignment system according to claim 2, it is characterised in that：In step B, Radio noise is separated and suppression comprises the following steps,B1, several optional marked regions on image, record status attribute vector S=[s of each marked region1, s2, s3,, s4], wherein s1For phase attributes, s2For frequency attribute, s3For gray scale attribute, s4For position attribution；B2, the vectorial synthesis undulating value J of the status attribute of each marked region is calculated,,,,；B3, the confidence level R according to the vectorial synthesis undulating value J calculating marked regions of the status attribute of marked region,Wherein,~For weight coefficient；B4, maximum by confidence level and the marked region of confidence level minimum is contrasted, and obtains image deviations amount, travels through image deviations The phase code of amount and each frequency range in each marked region, if the traversing graph in a certain frequency range is as departure phase code and this frequency All marked region phase code all sames in section, then deleted this frequency range data in image.
- 4. the localization method of nuclear-magnetism microwave melt needle alignment system according to claim 3, it is characterised in that：In step C, Elimination is carried out to magnetic susceptibility artifact to comprise the following steps,C1, traversing graph picture, magnetic susceptibility artifact region is determined according to the graded of gradation of image；C2, use block of pixels progress of the block of pixels at magnetic susceptibility artifact areas outside edge to magnetic susceptibility artifact area inside edge Replace, linear fit is carried out to the gray value for replacing region after replacement, and the gray value of correspondence position is adjusted according to fitting result； Above-mentioned replacement process is circulated and carried out, until magnetic susceptibility artifact region is replaced completely；C3, the gradation of image after step C2 processing is finely adjusted, makes the gradient of the gradation of images of step C2 before and after the processing Change direction is identical.
- 5. the localization method of nuclear-magnetism microwave melt needle alignment system according to claim 4, it is characterised in that：In step D, Elimination is carried out to gibbs artifact to comprise the following steps,D1, Fourier decomposition is carried out to the image by step C processing, delete the picture content with Spline smoothing；If the frequency range where the picture content deleted in D2, step D1 is adjacent with the data band deleted in step B4, to step The view data deleted in rapid D1 and step B4 carries out Fourier decomposition again, and the data component of linear correlation is protected Stay, fill into the picture content after step D1 processing；D3, by after D2 is handled each picture content carry out Fourier inversion, the image for the pseudo- movie queen that is eliminated.
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Citations (5)
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| CN101515028A (en) * | 2008-02-19 | 2009-08-26 | 西门子（中国）有限公司 | Three-dimensional imaging method and system for alleviating magnetic susceptibility artifact |
| CN101810480A (en) * | 2010-04-16 | 2010-08-25 | 上海交通大学 | Method for removing truncation artifacts in magnetic resonance images based on missing data reconstruction |
| CN104394764A (en) * | 2012-06-28 | 2015-03-04 | 皇家飞利浦有限公司 | Dedicated user interface for mr-guided interstitial interventions |
| CN105286988A (en) * | 2015-10-12 | 2016-02-03 | 北京工业大学 | CT image-guided liver tumor thermal ablation needle location and navigation system |
| EP3150157A1 (en) * | 2014-05-28 | 2017-04-05 | Taewoong Medical Co., Ltd. | Device and method for detecting position of electrode inserted into human body |
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2017
- 2017-11-16 CN CN201711137792.7A patent/CN107890371B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101515028A (en) * | 2008-02-19 | 2009-08-26 | 西门子（中国）有限公司 | Three-dimensional imaging method and system for alleviating magnetic susceptibility artifact |
| CN101810480A (en) * | 2010-04-16 | 2010-08-25 | 上海交通大学 | Method for removing truncation artifacts in magnetic resonance images based on missing data reconstruction |
| CN104394764A (en) * | 2012-06-28 | 2015-03-04 | 皇家飞利浦有限公司 | Dedicated user interface for mr-guided interstitial interventions |
| EP3150157A1 (en) * | 2014-05-28 | 2017-04-05 | Taewoong Medical Co., Ltd. | Device and method for detecting position of electrode inserted into human body |
| CN105286988A (en) * | 2015-10-12 | 2016-02-03 | 北京工业大学 | CT image-guided liver tumor thermal ablation needle location and navigation system |
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Address after: The third and fourth floors of J5, Nanjing University of Technology Industrial Park, No. 15, Wanshou Road, Pukou Economic Development Zone, Nanjing, Jiangsu 210000 Patentee after: Nanjing Yigao Medical Technology Co.,Ltd. Address before: The third and fourth floors of J5, Nanjing University of Technology Industrial Park, No. 15, Wanshou Road, Pukou Economic Development Zone, Nanjing, Jiangsu 210000 Patentee before: NANJING ECO MICROWAVE SYSTEM Co.,Ltd. |