CN107875432A - A kind of composite nano fiber antiseptic dressing and preparation method thereof - Google Patents
A kind of composite nano fiber antiseptic dressing and preparation method thereof Download PDFInfo
- Publication number
- CN107875432A CN107875432A CN201810043603.8A CN201810043603A CN107875432A CN 107875432 A CN107875432 A CN 107875432A CN 201810043603 A CN201810043603 A CN 201810043603A CN 107875432 A CN107875432 A CN 107875432A
- Authority
- CN
- China
- Prior art keywords
- solution
- poly
- silver ion
- aspartate
- composite nano
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
- A61L2300/104—Silver, e.g. silver sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
Abstract
The invention discloses a kind of composite nano fiber antiseptic dressing and preparation method thereof, it is related to medical dressing technical field.The composite nano fiber antiseptic dressing and preparation method thereof, by using the water imbibition of poly-aspartate material, silver ion is adsorbed after poly-aspartate hydrogel nanofiber is prepared, is then reduced to Nano Silver, can avoid interfering Nano Silver addition spinning solution to spinning process；Using the ion complexation of poly-aspartate, elder generation and silver ion complexation, it is then Nano Silver by silver ion reduction, the reunion of nano-Ag particles can be avoided；With reference to poly-aspartate material advantage and the sterilization idiocratic of Nano Silver, the poly-aspartate hydrogel being prepared/Nano Silver composite nano fiber antiseptic dressing has the high-specific surface area of nanofibrous structures, can be with quick imbibition, while has antibacterial action, and method is simple, cost is relatively low.
Description
Technical field
The present invention relates to medical dressing technical field, more particularly to a kind of composite nano fiber antiseptic dressing and its preparation side
Method.
Background technology
The environment of moistening can promote the formation of epithelium, accelerating wound healing.In order to keep the wetability of the surface of a wound, hydrogel
Dressing arises at the historic moment.Hydrogel, which can play, in dressing absorbs wound fluid, keeps surface of a wound wetting, debridement and accelerate wound
The effect of healing.The hydrogel nanofiber being prepared using electrostatic spinning technique, fibre diameter is thinner, has very high ratio
Surface area, can be with Fast-swelling imbibition；Hydrogel nanofiber has abundant pore space structure simultaneously, and porosity height is had an X-rayed ventilative
Performance is good.Before the special 26S Proteasome Structure and Function feature of hydrogel nanofiber makes it have wide application in medical dressing direction
Scape.Poly-aspartate is amino acid polymer a kind of biodegradable and with good biocompatibility, is contained in molecule rich
Carboxyl, amino, the amido link isopolarity group of richness, have excellent hydrophily and water solubility, are to prepare hydrogel nanofiber
Ideal material.
In order to prevent wound infection, wound dressing needs not only to enough quick imbibitions and good gas permeability, antibiotic property
It is an important evaluation index of wound dressing performance.The characteristics of Nano Silver is due to its broad-spectrum sterilization and excellent sterilizing ability by
The concern of people has been arrived, has been applied to the multiple fields such as antiseptic dressing, antibacterial fabric, antibacterial tableware at present.In hydrogel
Nano Silver is added in nanofiber, its anti-microbial property, performance of the lifting hydrogel nanofiber as wound dressing can be assigned.
However, the material that hydrogel nanofiber is prepared currently with electrostatic spinning method is less, the hydrogel on being loaded with Nano Silver is received
The research of rice fiber is relatively fewer, existing to prepare the antibacterial that the technology of composite nano fiber antiseptic dressing obtains using Nano Silver and apply
Material weight, Nano Silver it is dispersed poor, prepare and storage cost it is higher.
The content of the invention
In view of the above-mentioned problems existing in the prior art, the invention provides a kind of composite nano fiber antiseptic dressing and its system
Preparation Method.
First aspect according to embodiments of the present invention, there is provided a kind of preparation method of composite nano fiber antiseptic dressing, institute
The method of stating includes：
Using the intermediate polysuccinimide of poly-aspartate as electrostatic spinning raw material, the polysuccinimide is dissolved in two
Configuration obtains the spinning solution that concentration is 20% ~ 35% after NMF, and carrying out electrostatic spinning to the spinning solution obtains poly- amber
Amber acid imide nanofiber mats；
After the polysuccinimide nanofiber mats to be immersed to the mol/L of 0.15mol/L ~ 0.2 cross-linking agent solution crosslinking 1h,
Aqueous slkali is added to the cross-linking agent solution to be hydrolyzed, and obtains poly-aspartate hydrogel nanofiber；
The poly-aspartate hydrogel nanofiber is immersed in silver ion solution and taken out after preset duration, then is entered with distilled water
Water-filling is washed, and obtains the poly-aspartate hydrogel nanofiber containing silver ion；
The poly-aspartate hydrogel nanofiber containing silver ion is placed in preset duration in silver ion reduction agent solution
Afterwards, the composite nano fiber antiseptic dressing is taken out and washed, cool drying from the silver ion reduction agent solution,
Obtain composite nano fiber antiseptic dressing, the silver ion in the poly-aspartate hydrogel nanofiber containing silver ion exists
Nano Silver is reduced in the silver ion reduction agent solution.
In a preferred embodiment, the cross-linking agent solution is ethylenediamine solution or hexamethylene diamine solution.
In a preferred embodiment, the silver ion solution is AgNO3Solution, the AgNO3The concentration of solution is
0.01mol/L~0.1mol/L。
In a preferred embodiment, the silver ion solution is CH3COOAg solution, the CH3COOAg solution it is dense
Spend for 0.01mol/L ~ 0.1mol/L.
In a preferred embodiment, the silver ion reducing agent is NaBH4Etc. the concentration of the silver ion reducing agent
For 0.03mol/L ~ 0.1mol/L.
In a preferred embodiment, the aqueous slkali is NaOH solution, the concentration of the aqueous slkali for 0.1mol/L ~
1 mol/L。
Second aspect according to embodiments of the present invention, there is provided a kind of composite nano fiber antiseptic dressing, the composite Nano
Fibre antibacterial dressing is prepared by the preparation method of any of the above-described described composite nano fiber antiseptic dressing.
Compared with prior art, a kind of composite nano fiber antiseptic dressing provided by the invention and preparation method thereof have with
Lower advantage：
A kind of composite nano fiber antiseptic dressing provided by the invention and preparation method thereof, by using poly-aspartate material
Water imbibition, silver ion is adsorbed after poly-aspartate hydrogel nanofiber is prepared, is then reduced to Nano Silver, can be kept away
Exempt to interfere Nano Silver addition spinning solution to spinning process；Using the ion complexation of poly-aspartate, first with silver from
Son complexing, is then Nano Silver by silver ion reduction, can avoid the reunion of nano-Ag particles；It is excellent with reference to poly-aspartate material
The sterilization idiocratic of gesture and Nano Silver, the poly-aspartate hydrogel being prepared/Nano Silver composite nano fiber antiseptic dressing tool
There is the high-specific surface area of nanofibrous structures, can be with quick imbibition, while there is antibacterial action, and method is simple, cost is relatively low.
Brief description of the drawings
Accompanying drawing herein is merged in specification and forms the part of this specification, shows the implementation for meeting the present invention
Example, and in specification together for explaining principle of the invention.
Fig. 1 is a kind of method of the preparation method of composite nano fiber antiseptic dressing according to an exemplary embodiment
Flow chart.
Fig. 2 is a kind of fiber scanning of poly-aspartate hydrogel nanofiber according to another exemplary embodiment
Figure.
Fig. 3 is a kind of fiber ESEM of composite nano fiber antiseptic dressing according to another exemplary embodiment
Figure.
Embodiment
Below in conjunction with specific embodiment（But it is not limited to illustrated embodiment) present invention is described in detail with accompanying drawing, the present embodiment
Specific method only should not be limited by the examples for the explanation present invention, the scope of the present invention, and the present invention can make various in the application
The modification and variation of form and structure, these are similarly in the present patent application right based on the equivalent form of value on the basis of the present invention will
Seek protection domain.
Embodiment 1
Fig. 1 is a kind of method flow of the preparation method of composite nano fiber antiseptic dressing according to an exemplary embodiment
Figure, methods described include：
Step 101, it is using the intermediate polysuccinimide of poly-aspartate as electrostatic spinning raw material, the poly- succinyl is sub-
Configuration obtains the spinning solution that concentration is 20% ~ 35% after amine is dissolved in dimethylformamide, and electrostatic spinning is carried out to the spinning solution
Obtain polysuccinimide nanofiber mats.
The molecular weight of polysuccinimide is 31500.
Step 102, the crosslinking agent that the polysuccinimide nanofiber mats are immersed to the mol/L of 0.15mol/L ~ 0.2 is molten
After liquid crosslinking 1h, add aqueous slkali to the cross-linking agent solution and be hydrolyzed, obtain poly-aspartate hydrogel nanofiber.
Step 103, the poly-aspartate hydrogel nanofiber is immersed in silver ion solution and taken out after preset duration,
Washed again with distilled water, obtain the poly-aspartate hydrogel nanofiber containing silver ion.
Step 104, that the poly-aspartate hydrogel nanofiber containing silver ion is placed in into silver ion reducing agent is molten
In liquid after preset duration, the composite nano fiber antiseptic dressing is taken out and washed from the silver ion reduction agent solution
Wash, cool drying, obtain composite nano fiber antiseptic dressing, the poly-aspartate hydrogel nanofiber containing silver ion
Interior silver ion is reduced to Nano Silver in the silver ion reduction agent solution.
In a preferred embodiment, the cross-linking agent solution is ethylenediamine solution or hexamethylene diamine solution.
In a preferred embodiment, the silver ion solution is AgNO3Solution, the AgNO3The concentration of solution is
0.01mol/L~0.1mol/L。
In a preferred embodiment, the silver ion solution is CH3COOAg solution, the CH3COOAg solution it is dense
Spend for 0.01mol/L ~ 0.1mol/L.
In a preferred embodiment, the silver ion reducing agent is the concentration of the silver ion reducing agents such as NaBH4
For 0.03mol/L ~ 0.1mol/L.
In a preferred embodiment, the aqueous slkali is NaOH solution, the concentration of the aqueous slkali for 0.5mol/L ~
1 mol/L。
In summary, a kind of composite nano fiber antiseptic dressing provided by the invention and preparation method thereof, by using poly-
The water imbibition of aspartic acid material, silver ion is adsorbed after poly-aspartate hydrogel nanofiber is prepared, is then reduced
For Nano Silver, can avoid interfering Nano Silver addition spinning solution to spinning process；Utilize the ion of poly-aspartate
Complexing, elder generation and silver ion complexation, it is then Nano Silver by silver ion reduction, the reunion of nano-Ag particles can be avoided；With reference to
The sterilization idiocratic of poly-aspartate material advantage and Nano Silver, the poly-aspartate hydrogel being prepared/Nano Silver is compound are received
Rice fibre antibacterial dressing has the high-specific surface area of nanofibrous structures, can be with quick imbibition, while has antibacterial action, and side
Method is simple, and cost is relatively low.
Embodiment 2
（1）It is using the intermediate polysuccinimide of poly-aspartate as electrostatic spinning raw material, the polysuccinimide is molten
Configuration obtains the spinning solution that concentration is 34wt% after dimethylformamide, and carrying out electrostatic spinning to the spinning solution obtains poly- amber
Amber acid imide nanofiber mats.
（2）After the polysuccinimide nanofiber mats to be immersed to 0.15mol/L ethylenediamine solution crosslinking 1h, to institute
The NaOH solution for stating cross-linking agent solution addition 0.5mol/L is hydrolyzed, and obtains poly-aspartate hydrogel nanofiber, this is poly-
The fiber scanning figure of aspartic acid hydrogel nanofiber is as shown in Figure 2.
（3）The poly-aspartate hydrogel nanofiber is immersed to 0.05 mol/L AgNO3Taken out in solution after 8h,
Washed again with distilled water, obtain the poly-aspartate hydrogel nanofiber containing silver ion.
（4）It is 0.1mol/L's that the poly-aspartate hydrogel nanofiber containing silver ion is placed in into concentration
NaBH4In solution after 30min, the composite nano fiber antiseptic dressing is taken out from the silver ion reduction agent solution and gone forward side by side
Row washing, cool drying, obtain composite nano fiber antiseptic dressing, the fiber ESEM of the composite nano fiber antiseptic dressing
Silver ion in the figure poly-aspartate hydrogel nanofiber containing silver ion as shown in Figure 3 is in the silver ion reduction
Nano Silver is reduced in agent solution.
Embodiment 3
（1）It is using the intermediate polysuccinimide of poly-aspartate as electrostatic spinning raw material, the polysuccinimide is molten
Configuration obtains the spinning solution that concentration is 30wt% after dimethylformamide, and carrying out electrostatic spinning to the spinning solution obtains poly- amber
Amber acid imide nanofiber mats.
（2）After the polysuccinimide nanofiber mats to be immersed to 0.2mol/L ethylenediamine solution crosslinking 1h, to institute
The NaOH solution for stating cross-linking agent solution addition 1mol/L is hydrolyzed, and obtains poly-aspartate hydrogel nanofiber.
（3）The poly-aspartate hydrogel nanofiber is immersed to 0.01 mol/L CH3Taken in COOAg solution after 8h
Go out, then washed with distilled water, obtain the poly-aspartate hydrogel nanofiber containing silver ion.
（4）It is 0.03mol/L's that the poly-aspartate hydrogel nanofiber containing silver ion is placed in into concentration
NaBH4In solution after 30min, the composite nano fiber antiseptic dressing is taken out from the silver ion reduction agent solution and gone forward side by side
Row washing, cool drying, obtain composite nano fiber antiseptic dressing, the poly-aspartate hydrogel nanometer containing silver ion
Intrastitial silver ion is reduced to Nano Silver in the silver ion reduction agent solution.
In summary, a kind of composite nano fiber antiseptic dressing provided by the invention and preparation method thereof, by using poly-
The water imbibition of aspartic acid material, silver ion is adsorbed after poly-aspartate hydrogel nanofiber is prepared, is then reduced
For Nano Silver, can avoid interfering Nano Silver addition spinning solution to spinning process；Utilize the ion of poly-aspartate
Complexing, elder generation and silver ion complexation, it is then Nano Silver by silver ion reduction, the reunion of nano-Ag particles can be avoided；With reference to
The sterilization idiocratic of poly-aspartate material advantage and Nano Silver, the poly-aspartate hydrogel being prepared/Nano Silver is compound are received
Rice fibre antibacterial dressing has the high-specific surface area of nanofibrous structures, can be with quick imbibition, while has antibacterial action, and side
Method is simple, and cost is relatively low.
Although being described in detail above with general explanation, embodiment and experiment to the present invention,
But on the basis of the present invention, it can be modified or improved, this will be apparent to those skilled in the art.Cause
This, these modifications or improvements, belong to the scope of protection of present invention without departing from theon the basis of the spirit of the present invention.
Those skilled in the art will readily occur to the other of the present invention after the invention of specification and practice here is considered
Embodiment.It is contemplated that cover the present invention any modification, purposes or adaptations, these modifications, purposes or
Adaptations follow the general principle of the present invention and including undocumented common knowledge in the art of the invention or
Conventional techniques.It should be appreciated that the invention is not limited in the accurate knot for being described above and being shown in the drawings
Structure, and various modifications and changes can be being carried out without departing from the scope.
Claims (7)
1. a kind of preparation method of composite nano fiber antiseptic dressing, it is characterised in that methods described includes：
Using the intermediate polysuccinimide of poly-aspartate as electrostatic spinning raw material, the polysuccinimide is dissolved in two
Configuration obtains the spinning solution that concentration is 20% ~ 35% after NMF, and carrying out electrostatic spinning to the spinning solution obtains poly- amber
Amber acid imide nanofiber mats；
After the polysuccinimide nanofiber mats to be immersed to the mol/L of 0.15mol/L ~ 0.2 cross-linking agent solution crosslinking 1h,
Aqueous slkali is added to the cross-linking agent solution to be hydrolyzed, and obtains poly-aspartate hydrogel nanofiber；
The poly-aspartate hydrogel nanofiber is immersed in silver ion solution and taken out after preset duration, then is entered with distilled water
Water-filling is washed, and obtains the poly-aspartate hydrogel nanofiber containing silver ion；
The poly-aspartate hydrogel nanofiber containing silver ion is placed in preset duration in silver ion reduction agent solution
Afterwards, the composite nano fiber antiseptic dressing is taken out and washed, cool drying from the silver ion reduction agent solution,
Obtain composite nano fiber antiseptic dressing, the silver ion in the poly-aspartate hydrogel nanofiber containing silver ion exists
Nano Silver is reduced in the silver ion reduction agent solution.
2. according to the method for claim 1, it is characterised in that the cross-linking agent solution is that ethylenediamine solution or hexamethylene diamine are molten
Liquid.
3. according to the method for claim 1, it is characterised in that the silver ion solution is AgNO3Solution, the AgNO3It is molten
The concentration of liquid is 0.01mol/L ~ 0.1mol/L.
4. according to the method for claim 1, it is characterised in that the silver ion solution is CH3COOAg solution, it is described
CH3The concentration of COOAg solution is 0.01mol/L ~ 0.1mol/L.
5. according to the method for claim 1, it is characterised in that the silver ion reducing agent is NaBH4Etc. the silver ion also
The concentration of former agent is 0.03mol/L ~ 0.1mol/L.
6. according to the method for claim 1, it is characterised in that the aqueous slkali is NaOH solution, the aqueous slkali it is dense
Spend for the mol/L of 0.1mol/L ~ 1.
7. a kind of composite nano fiber antiseptic dressing, it is characterised in that the composite nano fiber antiseptic dressing is by claim
The preparation method of any described composite nano fiber antiseptic dressings of 1-6 is prepared.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810043603.8A CN107875432B (en) | 2018-01-17 | 2018-01-17 | Composite nanofiber antibacterial dressing and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810043603.8A CN107875432B (en) | 2018-01-17 | 2018-01-17 | Composite nanofiber antibacterial dressing and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107875432A true CN107875432A (en) | 2018-04-06 |
| CN107875432B CN107875432B (en) | 2021-01-01 |
Family
ID=61770571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810043603.8A Active CN107875432B (en) | 2018-01-17 | 2018-01-17 | Composite nanofiber antibacterial dressing and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107875432B (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103061037A (en) * | 2013-01-11 | 2013-04-24 | 东华大学 | Method for manufacturing polyaspartic acid nano-fiber mat by electrostatic spinning |
| CN103088630A (en) * | 2011-10-28 | 2013-05-08 | 中国科学院化学研究所 | Preparation method of nanometer fiber film for wound healing promotion |
| CN103266474A (en) * | 2013-05-14 | 2013-08-28 | 东华大学 | Method for preparing polyaspartic acid nano hydrogel felt |
| KR20160126252A (en) * | 2015-04-23 | 2016-11-02 | 경희대학교 산학협력단 | Preparing method of AgNPs-chitosan nanofiber |
| CN107385562A (en) * | 2017-07-13 | 2017-11-24 | 青岛大学 | A kind of alginic acid/Nano Silver composite nano fiber and preparation method thereof |
-
2018
- 2018-01-17 CN CN201810043603.8A patent/CN107875432B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103088630A (en) * | 2011-10-28 | 2013-05-08 | 中国科学院化学研究所 | Preparation method of nanometer fiber film for wound healing promotion |
| CN103061037A (en) * | 2013-01-11 | 2013-04-24 | 东华大学 | Method for manufacturing polyaspartic acid nano-fiber mat by electrostatic spinning |
| CN103266474A (en) * | 2013-05-14 | 2013-08-28 | 东华大学 | Method for preparing polyaspartic acid nano hydrogel felt |
| KR20160126252A (en) * | 2015-04-23 | 2016-11-02 | 경희대학교 산학협력단 | Preparing method of AgNPs-chitosan nanofiber |
| CN107385562A (en) * | 2017-07-13 | 2017-11-24 | 青岛大学 | A kind of alginic acid/Nano Silver composite nano fiber and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 郭世伟等: "电纺含银纳米粒子复合纤维的制备及应用", 《化学进展》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN107875432B (en) | 2021-01-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106076283B (en) | A kind of nano-cellulose/poly-dopamine hydrogel adsorbent and the preparation method and application thereof | |
| CN108721635B (en) | Functionalized mesoporous silica, preparation method thereof and application method thereof in wound repair | |
| CN105688349A (en) | Anti-virus mask | |
| CN107708754B (en) | Antibacterial nanofiber | |
| CN112999404B (en) | Stretchable nanofiber membrane and preparation method and application thereof | |
| CN105413236A (en) | Super-hydrophilic oil water separation net film with antifouling and antibacterial functions and preparation as well as application thereof | |
| CN107904947A (en) | Revivable antibacterial nanofiber membrane and preparation method thereof | |
| CN111424425B (en) | Nano hemostatic and antibacterial composite material for vascular surgery and preparation method thereof | |
| JP2008161756A (en) | Toxic substance scavenger, process for removing toxic substance and nonwoven fabric | |
| CN114470296A (en) | Stable and super-strong antibacterial super-blood-dredging dressing and preparation method thereof | |
| JP2014012915A (en) | Crosslinked acrylate based super extra fine fiber structure | |
| TWI807276B (en) | Air filtration system, antiviral face mask, coating obtained by drying of a solution and coated object | |
| CN102251393B (en) | Surface modification method of aliphatic polyester electrospun fiber by using sodium alginate and gelatin | |
| KR101111226B1 (en) | Nanofiber nonwoven fabric having chitosan layer and manufacturing method thereof | |
| Zhang et al. | Combining Chitosan, Stearic Acid, and (Cu‐, Zn‐) MOFs to Prepare Robust Superhydrophobic Coatings with Biomedical Multifunctionalities | |
| CN107875432A (en) | A kind of composite nano fiber antiseptic dressing and preparation method thereof | |
| JP5075554B2 (en) | Hazardous substance removal material and hazardous substance removal method | |
| JP2009091686A (en) | Method for producing harmful substance-removing material | |
| CN112972750B (en) | Antibacterial and disinfectant nanofiber medical dressing and preparation method thereof | |
| JP5496450B2 (en) | Hazardous substance removal material and hazardous substance removal method | |
| JP4937952B2 (en) | Hazardous material removal material | |
| CN107964696B (en) | Composite nanofiber and preparation method thereof | |
| CN102112222A (en) | Hazardous substance removing material and method for removing hazardous substance | |
| JP2009172550A (en) | Toxic substance removal material and method for removing toxic substance | |
| JP4991478B2 (en) | Hazardous substance removal material and hazardous substance removal method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20221223 Address after: 450000 room 605, block a, No.60 Guoji Road, Jinshui District, Zhengzhou City, Henan Province Patentee after: Henan Xiangzhi Intellectual Property Service Co.,Ltd. Address before: 314000 2 building, Photovoltaic Science Park, 1288 Kang He road, Xiuzhou District, Jiaxing, Zhejiang. Patentee before: JIAXING University |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20221230 Address after: 257000 Room 101, Building 8, No. 17, Xinghuahe Road, Dongying District, Dongying City, Shandong Province Patentee after: Shandong rongyuankang Medical Technology Co.,Ltd. Address before: 450000 room 605, block a, No.60 Guoji Road, Jinshui District, Zhengzhou City, Henan Province Patentee before: Henan Xiangzhi Intellectual Property Service Co.,Ltd. |