CN107858683A - A kind of multifunctional antibiotic film and preparation method thereof - Google Patents

A kind of multifunctional antibiotic film and preparation method thereof Download PDF

Info

Publication number
CN107858683A
CN107858683A CN201711238416.7A CN201711238416A CN107858683A CN 107858683 A CN107858683 A CN 107858683A CN 201711238416 A CN201711238416 A CN 201711238416A CN 107858683 A CN107858683 A CN 107858683A
Authority
CN
China
Prior art keywords
tio
silverskin
nano particle
poly tetrafluoroethylene
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201711238416.7A
Other languages
Chinese (zh)
Other versions
CN107858683B (en
Inventor
王云飞
高志廷
张黎燕
赵永猛
高志超
武明超
王建雨
孟银娜
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Henan Mechanical and Electrical Vocational College
Original Assignee
Henan Mechanical and Electrical Vocational College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henan Mechanical and Electrical Vocational College filed Critical Henan Mechanical and Electrical Vocational College
Priority to CN201711238416.7A priority Critical patent/CN107858683B/en
Publication of CN107858683A publication Critical patent/CN107858683A/en
Application granted granted Critical
Publication of CN107858683B publication Critical patent/CN107858683B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C28/00—Coating for obtaining at least two superposed coatings either by methods not provided for in a single one of groups C23C2/00 - C23C26/00 or by combinations of methods provided for in subclasses C23C and C25C or C25D
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C14/00—Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material
    • C23C14/06—Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material characterised by the coating material
    • C23C14/14—Metallic material, boron or silicon
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C14/00—Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material
    • C23C14/22—Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material characterised by the process of coating
    • C23C14/34—Sputtering
    • C23C14/35—Sputtering by application of a magnetic field, e.g. magnetron sputtering
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C16/00—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes
    • C23C16/44—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating
    • C23C16/50—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating using electric discharges
    • C23C16/513—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating using electric discharges using plasma jets
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C16/00—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes
    • C23C16/56—After-treatment
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C24/00—Coating starting from inorganic powder
    • C23C24/02—Coating starting from inorganic powder by application of pressure only
    • C23C24/04—Impact or kinetic deposition of particles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Mechanical Engineering (AREA)
  • Metallurgy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plasma & Fusion (AREA)
  • Laminated Bodies (AREA)
  • Catalysts (AREA)
  • Physical Vapour Deposition (AREA)
  • Disinfection, Sterilisation Or Deodorisation Of Air (AREA)

Abstract

The invention discloses a kind of multifunctional antibiotic film, including matrix, one layer of silverskin is covered on matrix, one layer of TiO is covered on silverskin2Nano particle, TiO2A strata tetrafluoroethylene is covered on nano particle, the surface setting of poly tetrafluoroethylene is fluted.The silverskin that the present invention uses, reflectivity can be made to reach 99%, enhance bactericidal effect；The TiO of use2Nano-particle diameter is 20 30nm, can nanosecond, psec time in produce OH‑And O2 ‑Deng radical anion, the bacterium of surrounding is attacked.The poly tetrafluoroethylene of use, there is excellent chemical stability, corrosion resistance, high lubrication, non-stick, electrical insulating property and good anti-aging endurance, can the long-term work at a temperature of+250 DEG C to 180 DEG C, ensure that the service life of film；The groove prepared using nano impression mode, increases specific surface area so that bactericidal effect improves.

Description

A kind of multifunctional antibiotic film and preparation method thereof
Technical field
The invention belongs to field of biomedicine technology, and in particular to a kind of multifunctional antibiotic film and preparation method thereof.
Background technology
With industrialized progress, people carry out unbriddled plunder to resource, cause water pollution, trees are destroyed, useless Progressively the increasing of thing rubbish, the contaminant particle such as dust phenomena such as increasing among air.It is reasonable that people are not carried out to waste Processing, destroy original ecological balance, grown substantial amounts of harmful bacteria, this drastically influence the health of people. Meanwhile with the technology innovation of Medical Devices, people have a high requirement to own health, which forms a lance Shield.
TiO2Nano material can adsorb oxygen and moisture in the presence of light with activated surface layer, produce OH-And O2 -Deng freely Base, this free radical can kill bacterium.TiO2Nano material has effect harmless to the human body, no strange taste, water-fastness spy Point.Therefore, TiO2Nano material is handled extensively using with water body, the industry such as medicine equipment, is a kind of activity of safe chemistry energy Material, play a part of restraining and sterilizing bacteria.
In medical device industry, a kind of composite disinfecting film is that have TiO by Ag films and disperse2The polytetrafluoro of nano particle The layer film of vinyl film 2 is formed.Current preparation technology is 200nm thickness Ag films prepared by wet method, is mixed in polytetrafluoroethylene (PTFE) Close in solution and adulterate TiO2Nano particle, this mixed liquor is coated on Ag films, heated, polytetrafluoroethylsolution solution Solvent is volatilized, and the polytetrafluoroethylene film of about 200nm thickness has been obtained on Ag films surface.
Such a technique, first, wet method is silver-plated, security is a big problem；Second, polytetrafluoroethylene film adhesive force Difference, easily come off；Third, the thickness of film layer is not easily controlled, this has had a strong impact on the application value of this film.
The content of the invention
The technical problem to be solved in the present invention is that the silver-plated security of wet method is poor, uniformity of film is not easily controlled, adhesion Difference, to solve the above problems, the present invention provides a kind of multifunctional antibiotic film and preparation method thereof.
The purpose of the present invention is realized in the following manner：
A kind of multifunctional antibiotic film, including matrix, one layer of silverskin is covered on matrix, one layer of TiO is covered on silverskin2Nanometer Grain, TiO2A strata tetrafluoroethylene is covered on nano particle, the surface setting of poly tetrafluoroethylene is fluted.
The thickness of the silverskin is 200-300nm, and the thickness of poly tetrafluoroethylene is 200-300 nm.
The preparation method of multifunctional antibiotic film described above, is comprised the following steps that：
（1）Plate silverskin：Silverskin is plated on matrix；
（2）Spray TiO2Nano particle：In silverskin surface spraying TiO2Nano particle；
（3）Plate poly tetrafluoroethylene：With TiO2The silverskin surface plating poly tetrafluoroethylene of nano particle；
（4）Impressing：Groove is imprinted out on poly tetrafluoroethylene.
Step（1）In, silverskin is plated using magnetron sputtering plating mode.
The process conditions of the magnetron sputtering plating are as follows：Φ 60mm, thickness are used as 4-6mm silver-colored target, target spacing It is adjusted to 60mm, power 100-150W, DC mode sputtering.
Step（2）In, TiO is sprayed using injecting type air gun2Nano particle, TiO2After nano particle spraying terminates, using suction Dust and gas ball dispels unnecessary TiO2 nano particles.
Step（3）In, using plasma strengthens chemical vapour deposition technique with TiO2The silverskin surface of nano particle Plate poly tetrafluoroethylene.
The process conditions of the plasma enhanced chemical vapor deposition method are as follows：Sample stage is highly 30-40mm, air pressure 15-20Pa, power 100-150W.
Step（4）In, using nano-imprinting method, groove is imprinted out on poly tetrafluoroethylene.
Step（4）In, the single projection cylinder height of the impressing mould used is 150-200nm, body diameter Φ 160-200nm。
The silverskin used relative to prior art, the present invention, can make reflectivity reach 99%, enhance bactericidal effect；Adopt TiO2Nano-particle diameter is 20-30nm.Can nanosecond, psec time in produce OH-And O2 -Deng free radical bear from Son, attack the bacterium of surrounding.There is very strong sterilization effect to mushrooms such as green bacillus, Escherichia coli, salmonella, aspergillins； The poly tetrafluoroethylene of use, there is excellent chemical stability, corrosion resistance, high lubrication, non-stick, electrical insulating property and well Anti-aging endurance, can the long-term work at a temperature of+250 DEG C to -180 DEG C, ensure that the service life of film；Using nanometer Groove prepared by impressing mode, increases specific surface area so that bactericidal effect improves.
After PolytetrafluoroethylFilm Film has adsorbed water and oxygen, in nano particle TiO2Under catalytic action, generate OH-And O2 -Deng radical anion, these anions are enriched in groove walls, kill the bacterium of film surface.O2 -Can with it is thin Organic matter is reacted in bacterium, and then kills bacterium.OH-It can be broken with the unsaturated bond and hydrogen atom of organic matter in attack bacteria The molecular structure of organic matter in bad bacterium.Organic matter and bacteria is decomposed into CO2With H2O。
Brief description of the drawings
Fig. 1 is the structural representation after matrix plating silverskin.
Fig. 2 is that TiO is coated on silverskin2Schematic diagram afterwards.
Fig. 3 is TiO2Structural representation after upper plating poly tetrafluoroethylene.
Fig. 4 is the structural representation after nano impression.
Fig. 5 is to eliminate bacterium process schematic.
Fig. 6 is the fungistatic effect comparison diagram of embodiment 3 and control sample.
Wherein, 1 is matrix；2 be silverskin；3 be TiO2Nano particle；4 be poly tetrafluoroethylene；5 be groove.
Embodiment
Embodiment 1：
As shown in accompanying drawing 1-5, a kind of multifunctional antibiotic film, including matrix 1 covers one layer of silverskin 2 on matrix 1, on silverskin 2 Cover one layer of TiO2Nano particle 3, TiO2A strata tetrafluoroethylene 4, the surface of poly tetrafluoroethylene 4 are covered on nano particle 3 Set fluted 5.
The thickness of silverskin 2 is 200-300nm, and the thickness of poly tetrafluoroethylene 4 is 200-300 nm.
The preparation method of multifunctional antibiotic film described above, is comprised the following steps that：
（1）Plate silverskin：Silverskin is plated on matrix；
（2）Spray TiO2Nano particle：In silverskin surface spraying TiO2Nano particle；
（3）Plate poly tetrafluoroethylene：With TiO2The silverskin surface plating poly tetrafluoroethylene of nano particle；
（4）Impressing：Groove is imprinted out on poly tetrafluoroethylene.
Step（1）In, silverskin is plated using magnetron sputtering plating mode.
The process conditions of the magnetron sputtering plating are as follows：Φ 60mm, thickness are used as 4-6mm silver-colored target, target spacing It is adjusted to 60mm, power 100-150W, DC mode sputtering.
Step（2）In, TiO is sprayed using injecting type air gun2Nano particle, TiO2After nano particle spraying terminates, using suction Dust and gas ball dispels unnecessary TiO2 nano particles.
Step（3）In, using plasma strengthens chemical vapour deposition technique with TiO2The silverskin surface of nano particle Plate poly tetrafluoroethylene.In cavity, C is passed through4F8Gas, poly tetrafluoroethylene is prepared using hyperbar, low-power mode.
The process conditions of the plasma enhanced chemical vapor deposition method are as follows：Sample stage is highly 30-40mm, air pressure 15-20Pa, power 100-150W.
Step（4）In, using nano-imprinting method, groove is imprinted out on poly tetrafluoroethylene.First by polytetrafluoroethyl-ne Alkene film is heated to 180-220 DEG C of progress vitrifying processing, and impressing processing is then carried out under the mould of design size.
Step（4）In, the single projection cylinder height of the impressing mould used is 150-200nm, body diameter Φ 160-200nm。
Embodiment 2：
A kind of multifunctional antibiotic film, including matrix 1, one layer of silverskin 2 is covered on matrix 1, one layer of TiO is covered on silverskin 22Receive Rice grain 3, TiO2A strata tetrafluoroethylene 4 is covered on nano particle 3, the surface of poly tetrafluoroethylene 4 sets fluted 5.
The thickness of silverskin 2 is 200nm, and the thickness of poly tetrafluoroethylene 4 is 200 nm.
The preparation method of multifunctional antibiotic film described above, is comprised the following steps that：
（1）Plate silverskin：Silverskin is plated on matrix using magnetron sputtering plating mode, the process conditions of magnetron sputtering plating are as follows： Using Φ 60mm, thickness, target spacing is adjusted to 60mm, power 100W, DC mode sputtering for 4mm silver-colored target.
（2）Spray TiO2Nano particle：Using injecting type air gun in silverskin surface spraying TiO2Nano particle, TiO2Nanometer After particle spray coating terminates, using dust suction balloon by unnecessary TiO2Nano particle dispels；
（3）Plate poly tetrafluoroethylene：Using plasma strengthens chemical vapour deposition technique with TiO2The silverskin of nano particle Plate poly tetrafluoroethylene in surface.In cavity, C is passed through4F8Gas, polytetrafluoroethylene (PTFE) is prepared using hyperbar, low-power mode Film.The process conditions of plasma enhanced chemical vapor deposition method are as follows：Sample stage is highly 30mm, air pressure 15Pa, power 100W。
（4）Impressing：Using nano-imprinting method, groove is imprinted out on poly tetrafluoroethylene.First by polytetrafluoroethylene (PTFE) Film is heated to 180 DEG C of progress vitrifying processing, and impressing processing is then carried out under the mould of design size.The impressing mould of use Single projection cylinder height be 150nm, body diameter is Φ 160nm.
Embodiment 3：
A kind of multifunctional antibiotic film, including matrix 1, one layer of silverskin 2 is covered on matrix 1, one layer of TiO is covered on silverskin 22Receive Rice grain 3, TiO2A strata tetrafluoroethylene 4 is covered on nano particle 3, the surface of poly tetrafluoroethylene 4 sets fluted 5.
The thickness of silverskin 2 is 220nm, and the thickness of poly tetrafluoroethylene 4 is 220 nm.
The preparation method of multifunctional antibiotic film described above, is comprised the following steps that：
（1）Plate silverskin：Silverskin is plated on matrix using magnetron sputtering plating mode, the process conditions of magnetron sputtering plating are as follows： Using Φ 60mm, thickness, target spacing is adjusted to 60mm, power 110W, DC mode sputtering for 4.5mm silver-colored target.
（2）Spray TiO2Nano particle：Using injecting type air gun in silverskin surface spraying TiO2Nano particle, TiO2Nanometer After particle spray coating terminates, using dust suction balloon by unnecessary TiO2Nano particle dispels；
（3）Plate poly tetrafluoroethylene：Using plasma strengthens chemical vapour deposition technique with TiO2The silverskin of nano particle Plate poly tetrafluoroethylene in surface.In cavity, C is passed through4F8Gas, polytetrafluoroethylene (PTFE) is prepared using hyperbar, low-power mode Film.The process conditions of plasma enhanced chemical vapor deposition method are as follows：Sample stage is highly 32mm, air pressure 16Pa, power 110W。
（4）Impressing：Using nano-imprinting method, groove is imprinted out on poly tetrafluoroethylene.First by polytetrafluoroethylene (PTFE) Film is heated to 190 DEG C of progress vitrifying processing, and impressing processing is then carried out under the mould of design size.The impressing mould of use Single projection cylinder height be 160nm, body diameter is Φ 170nm.
Embodiment 4：
A kind of multifunctional antibiotic film, including matrix 1, one layer of silverskin 2 is covered on matrix 1, one layer of TiO is covered on silverskin 22Receive Rice grain 3, TiO2A strata tetrafluoroethylene 4 is covered on nano particle 3, the surface of poly tetrafluoroethylene 4 sets fluted 5.
The thickness of silverskin 2 is 240nm, and the thickness of poly tetrafluoroethylene 4 is 240 nm.
The preparation method of multifunctional antibiotic film described above, is comprised the following steps that：
（1）Plate silverskin：Silverskin is plated on matrix using magnetron sputtering plating mode, the process conditions of magnetron sputtering plating are as follows： Using Φ 60mm, thickness, target spacing is adjusted to 60mm, power 120W, DC mode sputtering for 5mm silver-colored target.
（2）Spray TiO2Nano particle：Using injecting type air gun in silverskin surface spraying TiO2Nano particle, TiO2Nanometer After particle spray coating terminates, using dust suction balloon by unnecessary TiO2Nano particle dispels；
（3）Plate poly tetrafluoroethylene：Using plasma strengthens chemical vapour deposition technique with TiO2The silverskin of nano particle Plate poly tetrafluoroethylene in surface.In cavity, C is passed through4F8Gas, polytetrafluoroethylene (PTFE) is prepared using hyperbar, low-power mode Film.The process conditions of plasma enhanced chemical vapor deposition method are as follows：Sample stage is highly 34mm, air pressure 17Pa, power 120W。
（4）Impressing：Using nano-imprinting method, groove is imprinted out on poly tetrafluoroethylene.First by polytetrafluoroethylene (PTFE) Film is heated to 200 DEG C of progress vitrifying processing, and impressing processing is then carried out under the mould of design size.The impressing mould of use Single projection cylinder height be 170nm, body diameter is Φ 180nm.
Embodiment 5：
A kind of multifunctional antibiotic film, including matrix 1, one layer of silverskin 2 is covered on matrix 1, one layer of TiO is covered on silverskin 22Receive Rice grain 3, TiO2A strata tetrafluoroethylene 4 is covered on nano particle 3, the surface of poly tetrafluoroethylene 4 sets fluted 5.
The thickness of silverskin 2 is 260nm, and the thickness of poly tetrafluoroethylene 4 is 260 nm.
The preparation method of multifunctional antibiotic film described above, is comprised the following steps that：
（1）Plate silverskin：Silverskin is plated on matrix using magnetron sputtering plating mode, the process conditions of magnetron sputtering plating are as follows： Using Φ 60mm, thickness, target spacing is adjusted to 60mm, power 130W, DC mode sputtering for 5.5mm silver-colored target.
（2）Spray TiO2Nano particle：Using injecting type air gun in silverskin surface spraying TiO2Nano particle, TiO2Nanometer After particle spray coating terminates, using dust suction balloon by unnecessary TiO2Nano particle dispels；
（3）Plate poly tetrafluoroethylene：Using plasma strengthens chemical vapour deposition technique with TiO2The silverskin of nano particle Plate poly tetrafluoroethylene in surface.In cavity, C is passed through4F8Gas, polytetrafluoroethylene (PTFE) is prepared using hyperbar, low-power mode Film.The process conditions of plasma enhanced chemical vapor deposition method are as follows：Sample stage is highly 36mm, air pressure 18Pa, power 130W。
（4）Impressing：Using nano-imprinting method, groove is imprinted out on poly tetrafluoroethylene.First by polytetrafluoroethylene (PTFE) Film is heated to 210 DEG C of progress vitrifying processing, and impressing processing is then carried out under the mould of design size.The impressing mould of use Single projection cylinder height be 180nm, body diameter is Φ 190nm.
Embodiment 6：
A kind of multifunctional antibiotic film, including matrix 1, one layer of silverskin 2 is covered on matrix 1, one layer of TiO is covered on silverskin 22Receive Rice grain 3, TiO2A strata tetrafluoroethylene 4 is covered on nano particle 3, the surface of poly tetrafluoroethylene 4 sets fluted 5.
The thickness of silverskin 2 is 280nm, and the thickness of poly tetrafluoroethylene 4 is 280 nm.
The preparation method of multifunctional antibiotic film described above, is comprised the following steps that：
（1）Plate silverskin：Silverskin is plated on matrix using magnetron sputtering plating mode, the process conditions of magnetron sputtering plating are as follows： Using Φ 60mm, thickness, target spacing is adjusted to 60mm, power 140W, DC mode sputtering for 5.8mm silver-colored target.
（2）Spray TiO2Nano particle：Using injecting type air gun in silverskin surface spraying TiO2Nano particle, TiO2Nanometer After particle spray coating terminates, using dust suction balloon by unnecessary TiO2Nano particle dispels；
（3）Plate poly tetrafluoroethylene：Using plasma strengthens chemical vapour deposition technique with TiO2The silverskin of nano particle Plate poly tetrafluoroethylene in surface.In cavity, C is passed through4F8Gas, polytetrafluoroethylene (PTFE) is prepared using hyperbar, low-power mode Film.The process conditions of plasma enhanced chemical vapor deposition method are as follows：Sample stage is highly 38mm, air pressure 19Pa, power 140W。
（4）Impressing：Using nano-imprinting method, groove is imprinted out on poly tetrafluoroethylene.First by polytetrafluoroethylene (PTFE) Film is heated to 215 DEG C of progress vitrifying processing, and impressing processing is then carried out under the mould of design size.The impressing mould of use Single projection cylinder height be 190nm, body diameter is Φ 200nm.
Embodiment 7：
A kind of multifunctional antibiotic film, including matrix 1, one layer of silverskin 2 is covered on matrix 1, one layer of TiO is covered on silverskin 22Receive Rice grain 3, TiO2A strata tetrafluoroethylene 4 is covered on nano particle 3, the surface of poly tetrafluoroethylene 4 sets fluted 5.
The thickness of silverskin 2 is 300nm, and the thickness of poly tetrafluoroethylene 4 is 300 nm.
The preparation method of multifunctional antibiotic film described above, is comprised the following steps that：
（1）Plate silverskin：Silverskin is plated on matrix using magnetron sputtering plating mode, the process conditions of magnetron sputtering plating are as follows： Using Φ 60mm, thickness, target spacing is adjusted to 60mm, power 150W, DC mode sputtering for 6mm silver-colored target.
（2）Spray TiO2Nano particle：Using injecting type air gun in silverskin surface spraying TiO2Nano particle, TiO2Nanometer After particle spray coating terminates, using dust suction balloon by unnecessary TiO2Nano particle dispels；
（3）Plate poly tetrafluoroethylene：Using plasma strengthens chemical vapour deposition technique with TiO2The silverskin of nano particle Plate poly tetrafluoroethylene in surface.In cavity, C is passed through4F8Gas, polytetrafluoroethylene (PTFE) is prepared using hyperbar, low-power mode Film.The process conditions of plasma enhanced chemical vapor deposition method are as follows：Sample stage is highly 40mm, air pressure 20Pa, power 150W。
（4）Impressing：Using nano-imprinting method, groove is imprinted out on poly tetrafluoroethylene.First by polytetrafluoroethylene (PTFE) Film is heated to 220 DEG C of progress vitrifying processing, and impressing processing is then carried out under the mould of design size.The impressing mould of use Single projection cylinder height be 200nm, body diameter is Φ 200nm.
Embodiment 8：
A kind of preparation method of multifunctional antibiotic film, is comprised the following steps that：
（1）Plate silverskin：The plated film on matrix, the Coating Materials are silver；
（2）Spray TiO2：Silver surface sprays TiO2。
（3）Plate poly tetrafluoroethylene：With TiO2Poly tetrafluoroethylene is plated on silver surface.
（4）Nano impression：Groove is imprinted out on poly tetrafluoroethylene film.
Step（1）In, using magnetron sputtering plating mode, silverskin 200nm is plated on matrix, process conditions are as follows：Using Φ 60mm, the silver-colored target that thickness is 6mm.Target spacing is adjusted to 60mm, power 100, DC mode sputtering.
Step（2）In, nano particle TiO is sprayed using injecting type air gun2To Ag films surface.
Step（3）In, using PECVD plated film modes, it is being loaded with nano particle TiO2The poly- of 200nm thickness is grown on silverskin Tetrafluoroethene.In cavity, C is passed through4F8Gas, process conditions are as follows：Sample stage is highly adjusted to 30mm, air pressure 15Pa, power 100W。
C4F8Gas is under plasmoid, cyclic structure dissociation, raw catenulate polytetrafluoroethylene film.Film is 100 It is heat-treated at DEG C so that chain structure is grown, and film becomes fine and close.Strengthen adhesion and hydrophobic performance.
Step（4）In, polytetrafluoroethylene (PTFE) is heated into 220 DEG C of progress vitrifying processing first, then in the mould of design size Impressing processing is carried out under tool.The single projection cylinder punch-pin of impressing mould is highly 200nm, and body diameter is Φ 200nm.
Polytetrafluoroethylene (PTFE) heats 220 DEG C so that part chain structure is destroyed, and can carry out the imprint process of next step.Can To form uniform groove structure in polytetrafluoroethylene (PTFE).
Produce, thickness is the Antibiotic Membrane that 400nm carries groove structure.
Embodiment 9：
A kind of preparation method of multifunctional antibiotic film, is comprised the following steps that：
（1）Silverskin is plated, using magnetron sputtering plating mode, silverskin 300nm is plated on matrix, process conditions are as follows：Using Φ 60mm, the silver-colored target that thickness is 4mm.Target spacing is adjusted to 60mm, power 150W, DC mode sputtering.
（2）Spray TiO2, nano particle TiO is sprayed using injecting type air gun2To Ag films surface.
（3）Poly tetrafluoroethylene is plated, using PECVD plated film modes, is being loaded with nano particle TiO2300 are grown on silverskin The polytetrafluoroethylene (PTFE) of nm thickness.In cavity, C is passed through4F8Gas, process conditions are as follows：Sample stage is highly adjusted to 40mm, gas Press 20Pa, power 150W.Plated film speed can reach 30nm/min.
（4）Nano impression, polytetrafluoroethylene (PTFE) is heated into 220 DEG C of progress vitrifying processing first, then in design size（Circle Post punch-pin is highly 200nm, and body diameter is Φ 200nm）Mould under carry out impressing processing.
Produce, thickness is the Antibiotic Membrane that 600nm carries groove structure.
Embodiment 10：
A kind of preparation method of multifunctional antibiotic film, is comprised the following steps that：
（1）Silverskin is plated, using magnetron sputtering plating mode, silverskin 200nm is plated on matrix, process conditions are as follows：Using Φ 60mm, the silver-colored target that thickness is 5mm.Target spacing is adjusted to 60mm, power 120W, DC mode sputtering.
（2）Spray TiO2, nano particle TiO is sprayed using injecting type air gun2To Ag films surface.
（3）Poly tetrafluoroethylene is plated, using PECVD plated film modes, is being loaded with nano particle TiO2200 are grown on silverskin The polytetrafluoroethylene (PTFE) of nm thickness.In cavity, C is passed through4F8Gas, process conditions are as follows：Sample stage is highly adjusted to 35mm, gas Press 18Pa, power 100W.Plated film speed can reach 20nm/min.
（4）Nano impression, polytetrafluoroethylene (PTFE) is heated into 200 DEG C of progress vitrifying processing first, then in design size（Circle Post punch-pin is highly 180nm, and body diameter is Φ 200nm）Mould under carry out impressing processing.
Produce, thickness is the Antibiotic Membrane that 400nm carries groove structure.
Antagonistic property can be evaluated using the absorbance of bacterial concentration, briefly, for bacterium solution, if the concentration of bacterium is high If, absorbance is just high.Sample causes the concentration step-down of bacterium solution, and bacterial concentration is more few better, and sample just has bacteriostasis property.
The height of microorganism concn is characterized using staphylococcus aureus culture medium turbidity height.Using control sample and reality The bacteriostatic film sample of the preparation of example 3 is applied, carries out the antibacterial tests of Antibiotic Membrane, the anti-bacterial result is as follows：It is from fig. 6, it can be seen that right More poor than sample antibiotic property, light absorption value is bigger than normal, and light absorption value keeps high stable state substantially；Bacteriostatic film prepared by embodiment 3 exists Within one week, good inhibition is kept to staphylococcus aureus always.
Above-mentioned control sample is existing composite disinfecting film.
Above-described is only the preferred embodiment of the present invention, it is noted that for those skilled in the art, Under the premise of general idea of the present invention is not departed from, some changes and improvements can also be made, these should also be considered as the present invention's Protection domain.

Claims (10)

  1. A kind of 1. multifunctional antibiotic film, it is characterised in that：Including matrix（1）, matrix（1）One layer of silverskin of upper covering（2）, silver Film（2）One layer of TiO of upper covering2Nano particle（3）, TiO2Nano particle（3）One strata tetrafluoroethylene of upper covering（4）, polytetrafluoro Vinyl film（4）Surface set it is fluted（5）.
  2. 2. multifunctional antibiotic film according to claim 1, it is characterised in that：The silverskin（2）Thickness be 200- 300nm, poly tetrafluoroethylene（4）Thickness be 200-300 nm.
  3. 3. the preparation method of multifunctional antibiotic film as claimed in claim 1 or 2, it is characterised in that：Comprise the following steps that：
    （1）Plate silverskin：Silverskin is plated on matrix；
    （2）Spray TiO2Nano particle：In silverskin surface spraying TiO2Nano particle；
    （3）Plate poly tetrafluoroethylene：With TiO2The silverskin surface plating poly tetrafluoroethylene of nano particle；
    （4）Impressing：Groove is imprinted out on poly tetrafluoroethylene.
  4. 4. the preparation method of multifunctional antibiotic film according to claim 1, it is characterised in that：Step（1）In, use Magnetron sputtering plating mode plates silverskin.
  5. 5. the preparation method of multifunctional antibiotic film according to claim 4, it is characterised in that：The magnetron sputtering The process conditions of film are as follows：Using Φ 60mm, thickness, target spacing is adjusted to 60mm, power 100- for 4-6mm silver-colored target 150W, DC mode sputtering.
  6. 6. the preparation method of multifunctional antibiotic film according to claim 1, it is characterised in that：Step（2）In, use Injecting type air gun sprays TiO2Nano particle, TiO2After nano particle spraying terminates, using dust suction balloon by unnecessary TiO2Nanometer Particle dispels.
  7. 7. the preparation method of multifunctional antibiotic film according to claim 1, it is characterised in that：Step（3）In, use Plasma enhanced chemical vapor deposition method is with TiO2The silverskin surface plating poly tetrafluoroethylene of nano particle.
  8. 8. the preparation method of multifunctional antibiotic film according to claim 7, it is characterised in that：The plasma increases The process conditions of extensive chemical vapour deposition process are as follows：Sample stage is highly 30-40mm, air pressure 15-20Pa, power 100-150W.
  9. 9. the preparation method of multifunctional antibiotic film according to claim 1, it is characterised in that：Step（4）In, use Nano-imprinting method, groove is imprinted out on poly tetrafluoroethylene.
  10. 10. the preparation method of multifunctional antibiotic film according to claim 1, it is characterised in that：Step（4）In, adopt The single projection cylinder height of impressing mould is 150-200nm, and body diameter is Φ 160-200nm.
CN201711238416.7A 2017-11-30 2017-11-30 A kind of multifunctional antibiotic film and preparation method thereof Expired - Fee Related CN107858683B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201711238416.7A CN107858683B (en) 2017-11-30 2017-11-30 A kind of multifunctional antibiotic film and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711238416.7A CN107858683B (en) 2017-11-30 2017-11-30 A kind of multifunctional antibiotic film and preparation method thereof

Publications (2)

Publication Number Publication Date
CN107858683A true CN107858683A (en) 2018-03-30
CN107858683B CN107858683B (en) 2019-11-08

Family

ID=61704191

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201711238416.7A Expired - Fee Related CN107858683B (en) 2017-11-30 2017-11-30 A kind of multifunctional antibiotic film and preparation method thereof

Country Status (1)

Country Link
CN (1) CN107858683B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108456869A (en) * 2018-04-12 2018-08-28 河南机电职业学院 A kind of mobile phone decorative pattern high abrasion microflute mold and preparation method thereof
CN109136906A (en) * 2018-10-23 2019-01-04 济南大学 Drilling platforms pusher surface coating production
CN110903514A (en) * 2019-11-26 2020-03-24 安徽正合雅聚新材料科技有限公司 Antibacterial agent with excellent water resistance, preparation method thereof and antibacterial product

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101098834A (en) * 2004-12-16 2008-01-02 格拉沃贝尔公司 Substrate with antimicrobial properties
CN101157023A (en) * 2007-10-25 2008-04-09 北京师范大学 A multi-channeling titania photocatalysis membrana and method for making same
CN101543780A (en) * 2009-04-30 2009-09-30 上海交通大学 Preparation method for Ag-TiO 2-MMT composite photocatalyst
CN101709464A (en) * 2009-11-19 2010-05-19 广州电器科学研究院 Method for preparing stainless steel surface nano antibacterial film
CN102758202A (en) * 2012-08-11 2012-10-31 西北有色金属研究院 Method for preparing biomedical titanium and titanium alloy surface antibacterial coatings
CN103102618A (en) * 2013-01-23 2013-05-15 浙江理工大学 TiO2@Ag/PVC (Poly Vinyl Chloride) composite antibacterial film and preparation method thereof
CN103132045A (en) * 2011-11-28 2013-06-05 英作纳米科技（北京）有限公司 Preparation method for coatings of medical supplies and products thereof
CN103935081A (en) * 2014-02-26 2014-07-23 东莞市万丰纳米材料有限公司 Permeable material with inorganic sterilization effect, and preparation method thereof
CN104120394A (en) * 2014-06-30 2014-10-29 左娟 Method for preparing Ag/TiO2 nano-composite color-changing material
CN204088397U (en) * 2014-09-25 2015-01-07 明冠新材料股份有限公司 The lithium battery encapsulation aluminum plastic film of a kind of top layer electrolyte resistance corrosion

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101098834A (en) * 2004-12-16 2008-01-02 格拉沃贝尔公司 Substrate with antimicrobial properties
CN101157023A (en) * 2007-10-25 2008-04-09 北京师范大学 A multi-channeling titania photocatalysis membrana and method for making same
CN101543780A (en) * 2009-04-30 2009-09-30 上海交通大学 Preparation method for Ag-TiO 2-MMT composite photocatalyst
CN101709464A (en) * 2009-11-19 2010-05-19 广州电器科学研究院 Method for preparing stainless steel surface nano antibacterial film
CN103132045A (en) * 2011-11-28 2013-06-05 英作纳米科技（北京）有限公司 Preparation method for coatings of medical supplies and products thereof
CN102758202A (en) * 2012-08-11 2012-10-31 西北有色金属研究院 Method for preparing biomedical titanium and titanium alloy surface antibacterial coatings
CN103102618A (en) * 2013-01-23 2013-05-15 浙江理工大学 TiO2@Ag/PVC (Poly Vinyl Chloride) composite antibacterial film and preparation method thereof
CN103935081A (en) * 2014-02-26 2014-07-23 东莞市万丰纳米材料有限公司 Permeable material with inorganic sterilization effect, and preparation method thereof
CN104120394A (en) * 2014-06-30 2014-10-29 左娟 Method for preparing Ag/TiO2 nano-composite color-changing material
CN204088397U (en) * 2014-09-25 2015-01-07 明冠新材料股份有限公司 The lithium battery encapsulation aluminum plastic film of a kind of top layer electrolyte resistance corrosion

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108456869A (en) * 2018-04-12 2018-08-28 河南机电职业学院 A kind of mobile phone decorative pattern high abrasion microflute mold and preparation method thereof
CN109136906A (en) * 2018-10-23 2019-01-04 济南大学 Drilling platforms pusher surface coating production
CN109136906B (en) * 2018-10-23 2020-06-26 济南大学 Preparation method of surface coating of drilling platform propeller
CN110903514A (en) * 2019-11-26 2020-03-24 安徽正合雅聚新材料科技有限公司 Antibacterial agent with excellent water resistance, preparation method thereof and antibacterial product

Also Published As

Publication number Publication date
CN107858683B (en) 2019-11-08

Similar Documents

Publication Publication Date Title
Parham et al. Antimicrobial treatment of different metal oxide nanoparticles: a critical review
CN103843822B (en) A kind of preparation method of CNT silver composite antibacterial material
CN107858683B (en) A kind of multifunctional antibiotic film and preparation method thereof
Zhang et al. Antibacterial activity of photocatalytic electrospun titania nanofiber mats and solution-blown soy protein nanofiber mats decorated with silver nanoparticles
Kushwaha et al. Preparation and characterization of self-photostabilizing UV-durable bionanocomposite membranes for outdoor applications
CN101983569B (en) Titanium dioxide nano antibacterial agent taking halloysite as carrier and preparation method thereof
Lin et al. Photocatalytic and antibacterial properties of medical‐grade PVC material coated with TiO2 film
Chuang et al. Metal oxide composite thin films made by magnetron sputtering for bactericidal application
CN112452683A (en) Infrared antibacterial coating and preparation method thereof
CN106811968A (en) A kind of shitosan photo-catalytic antibacterial towel
CN105565670A (en) Ceramic or enamel sterilization glaze material and preparation method and application thereof
CN1648178A (en) Long action negative ion antiseptic function paint
CN105771689A (en) High antimicrobial PVDF/GO/Ag composite membrane and preparation method thereof
Jia et al. Recent Advances in Dual‐Function Superhydrophobic Antibacterial Surfaces
CN103341356A (en) Processing method of water purifying agent of ceramic tourmaline-loaded titanium dioxide film
CN101481585A (en) Tourmaline gloss oil and preparation thereof
CN107327116A (en) Antibiotic plastic floor
CN108559118A (en) A kind of antimicrobial form carries silver-colored silastic material and preparation method thereof
Wang et al. Mildew resistance and antibacterial activity of plywood decorated with ZnO/TiO2 nanoparticle
CN103850416A (en) Photocatalytic wall paper
CN103897469A (en) Nanometer-level photocatalyst roll coating agent
KR20010069645A (en) Sterilization of water using the particles coated with silver
Fahmy et al. Silver/polyethylene glycol nanocomposite thin films and its biological applications
Sowmya et al. A Systematic Review Of Metallic Nanoparticles: Synthesis, Biological Activities & Applications
Voloshyna et al. «Green» synthesis of metal nanoparticles. Application and future perspective.

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20191108

Termination date: 20211130