CN107847743B - 刺激肾神经的系统 - Google Patents

刺激肾神经的系统 Download PDF

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CN107847743B
CN107847743B CN201680042513.6A CN201680042513A CN107847743B CN 107847743 B CN107847743 B CN 107847743B CN 201680042513 A CN201680042513 A CN 201680042513A CN 107847743 B CN107847743 B CN 107847743B
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renal
blood pressure
heart rate
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rdn
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CN107847743A (zh
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S·魏斯
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Koninklijke Philips NV
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Koninklijke Philips NV
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/36017—External stimulators, e.g. with patch electrodes with leads or electrodes penetrating the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10—Computer-aided planning, simulation or modelling of surgical operations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1477—Needle-like probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0502—Skin piercing electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00434—Neural system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00505—Urinary tract
    • A61B2018/00511—Kidney
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577—Ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00773—Sensed parameters
    • A61B2018/00839—Bioelectrical parameters, e.g. ECG, EEG
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2218/00—Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2218/001—Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body having means for irrigation and/or aspiration of substances to and/or from the surgical site
    • A61B2218/002—Irrigation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2505/00—Evaluating, monitoring or diagnosing in the context of a particular type of medical care
    • A61B2505/05—Surgical care

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Cardiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plasma & Fusion (AREA)
  • Otolaryngology (AREA)
  • Primary Health Care (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Robotics (AREA)
  • General Business, Economics & Management (AREA)
  • Vascular Medicine (AREA)
  • Physiology (AREA)
  • Business, Economics & Management (AREA)
  • Pathology (AREA)
  • Electrotherapy Devices (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
CN201680042513.6A 2015-07-21 2016-07-12 刺激肾神经的系统 Active CN107847743B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15177702 2015-07-21
EP15177702.6 2015-07-21
PCT/EP2016/066462 WO2017012907A1 (en) 2015-07-21 2016-07-12 System for stimulating renal nerves

Publications (2)

Publication Number Publication Date
CN107847743A CN107847743A (zh) 2018-03-27
CN107847743B true CN107847743B (zh) 2022-06-10

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US (3) US11547480B2 (https=)
EP (1) EP3325086B1 (https=)
JP (1) JP6998295B2 (https=)
CN (1) CN107847743B (https=)
WO (1) WO2017012907A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013134543A1 (en) 2012-03-08 2013-09-12 Medtronic Ardian Luxembourg Sarl Immune system neuromodulation and associated systems and methods
US10610292B2 (en) 2014-04-25 2020-04-07 Medtronic Ardian Luxembourg S.A.R.L. Devices, systems, and methods for monitoring and/or controlling deployment of a neuromodulation element within a body lumen and related technology
EP3791817B1 (en) 2014-10-01 2024-05-22 Medtronic Ardian Luxembourg S.à.r.l. Systems for evaluating neuromodulation therapy via hemodynamic responses
JP2017536187A (ja) 2014-12-03 2017-12-07 メタベンション インコーポレイテッド 神経または他の組織を調節するためのシステムおよび方法
WO2016100720A1 (en) 2014-12-17 2016-06-23 Medtronic Ardian Luxembourg S.A.R.L. Systems and methods for assessing sympathetic nervous system tone for renal neuromodulation therapy
US10524859B2 (en) 2016-06-07 2020-01-07 Metavention, Inc. Therapeutic tissue modulation devices and methods
CN111511302B (zh) 2017-11-17 2024-09-17 美敦力Af卢森堡有限责任公司 用于具有增强的神经靶向的神经调节的系统、设备以及相关联的方法
US11253189B2 (en) 2018-01-24 2022-02-22 Medtronic Ardian Luxembourg S.A.R.L. Systems, devices, and methods for evaluating neuromodulation therapy via detection of magnetic fields
US11717343B2 (en) 2018-01-24 2023-08-08 Medtronic Ireland Manufacturing Unlimited Company Systems, devices, and associated methods for neuromodulation in heterogeneous tissue environments
US10786306B2 (en) 2018-01-24 2020-09-29 Medtronic Ardian Luxembourg S.A.R.L. Denervation therapy
US10959669B2 (en) 2018-01-24 2021-03-30 Medtronic Ardian Luxembourg S.A.R.L. Systems and methods for assessing the efficacy of neuromodulation therapy
US12082917B2 (en) 2018-01-24 2024-09-10 Medtronic Ireland Manufacturing Unlimited Company Systems, devices, and methods for assessing efficacy of renal neuromodulation therapy
US11633120B2 (en) 2018-09-04 2023-04-25 Medtronic Ardian Luxembourg S.A.R.L. Systems and methods for assessing efficacy of renal neuromodulation therapy
CN112955974B (zh) 2018-10-26 2025-01-14 皇家飞利浦有限公司 用于确定肾脏去神经支配处置反应指数的设备、系统和方法
CN114224385B (zh) * 2022-02-28 2022-05-31 深圳高性能医疗器械国家研究院有限公司 一种无创肾交感神经活性检测系统及方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101443072A (zh) * 2006-03-06 2009-05-27 阿迪安公司 双侧肾神经调制的方法和装置
CN101940815A (zh) * 2004-10-05 2011-01-12 阿迪安公司 肾神经调节的方法和装置
EP2460486A1 (en) * 2010-12-06 2012-06-06 Biosense Webster, Inc. Treatment of atrial fibrillation using high-frequency pacing and ablation of renal nerves
CN102885648A (zh) * 2012-08-29 2013-01-23 中国人民解放军第三军医大学第一附属医院 肾脏去交感神经消融导管系统
CN103271766A (zh) * 2012-08-24 2013-09-04 苏州信迈医疗器械有限公司 一种用于标测和消融位于肾动脉上所分布的肾神经的装置
CN103767787A (zh) * 2014-01-24 2014-05-07 上海魅丽纬叶医疗科技有限公司 用于神经消融的射频消融方法和射频消融系统

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8145316B2 (en) * 2002-04-08 2012-03-27 Ardian, Inc. Methods and apparatus for renal neuromodulation
US9308044B2 (en) * 2002-04-08 2016-04-12 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US7162303B2 (en) * 2002-04-08 2007-01-09 Ardian, Inc. Renal nerve stimulation method and apparatus for treatment of patients
EP3581224A1 (en) 2008-08-05 2019-12-18 Antares Pharma, Inc. Multiple dosage injector
KR101567285B1 (ko) * 2009-10-12 2015-11-09 코나 메디컬, 인크. 신경의 에너지 조절
US8473067B2 (en) * 2010-06-11 2013-06-25 Boston Scientific Scimed, Inc. Renal denervation and stimulation employing wireless vascular energy transfer arrangement
ES2972941T3 (es) * 2011-08-26 2024-06-17 Symap Medical Suzhou Ltd Sistema para localizar e identificar nervios funcionales que inervan la pared de las arterias
US8702619B2 (en) * 2011-08-26 2014-04-22 Symap Holding Limited Mapping sympathetic nerve distribution for renal ablation and catheters for same
CN202637103U (zh) * 2011-08-26 2013-01-02 王捷 具有肾神经标测功能的导管
US9427579B2 (en) * 2011-09-29 2016-08-30 Pacesetter, Inc. System and method for performing renal denervation verification
US20130158509A1 (en) 2011-12-19 2013-06-20 Paul M. Consigny System, apparatus, and method for denervating an artery
US20130289650A1 (en) * 2012-04-25 2013-10-31 Pacesetter, Inc. Neuromodulation for Hypertension Control
EP2852339B1 (en) 2012-05-29 2020-12-23 Autonomix Medical, Inc. Endoscopic sympathectomy systems
US11357447B2 (en) * 2012-05-31 2022-06-14 Sonivie Ltd. Method and/or apparatus for measuring renal denervation effectiveness
WO2014070999A2 (en) 2012-11-05 2014-05-08 Landy Toth Systems, methods, and devices for monitoring and treatment of tissues within and/or through a lumen wall
US9974477B2 (en) * 2013-03-15 2018-05-22 St. Jude Medical, Cardiology Division, Inc. Quantification of renal denervation via alterations in renal blood flow pre/post ablation
CN103519887B (zh) * 2013-10-25 2016-04-20 乐普（北京）医疗器械股份有限公司 一种经皮射频消融去肾交感神经术用系统

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101940815A (zh) * 2004-10-05 2011-01-12 阿迪安公司 肾神经调节的方法和装置
CN101443072A (zh) * 2006-03-06 2009-05-27 阿迪安公司 双侧肾神经调制的方法和装置
EP2460486A1 (en) * 2010-12-06 2012-06-06 Biosense Webster, Inc. Treatment of atrial fibrillation using high-frequency pacing and ablation of renal nerves
CN103271766A (zh) * 2012-08-24 2013-09-04 苏州信迈医疗器械有限公司 一种用于标测和消融位于肾动脉上所分布的肾神经的装置
WO2014029355A1 (en) * 2012-08-24 2014-02-27 Symap Medical (Suzhou) , Ltd Device for mapping and ablating renal nerves distributed on the renal artery
CN102885648A (zh) * 2012-08-29 2013-01-23 中国人民解放军第三军医大学第一附属医院 肾脏去交感神经消融导管系统
CN103767787A (zh) * 2014-01-24 2014-05-07 上海魅丽纬叶医疗科技有限公司 用于神经消融的射频消融方法和射频消融系统

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Publication number Publication date
US12193753B2 (en) 2025-01-14
EP3325086A1 (en) 2018-05-30
CN107847743A (zh) 2018-03-27
WO2017012907A1 (en) 2017-01-26
US11547480B2 (en) 2023-01-10
JP6998295B2 (ja) 2022-01-18
EP3325086B1 (en) 2024-09-11
US20180214212A1 (en) 2018-08-02
US20250152246A1 (en) 2025-05-15
JP2018519963A (ja) 2018-07-26
US20230157758A1 (en) 2023-05-25

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