CN107837369A - 治疗鼻炎的中药组合物 - Google Patents
治疗鼻炎的中药组合物 Download PDFInfo
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- CN107837369A CN107837369A CN201711310295.2A CN201711310295A CN107837369A CN 107837369 A CN107837369 A CN 107837369A CN 201711310295 A CN201711310295 A CN 201711310295A CN 107837369 A CN107837369 A CN 107837369A
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Abstract
本发明涉及治疗鼻炎的中药组合物,所选中药药材八角莲、蝎子、蜈蚣、吹风蛇、五步蛇、洛石藤、吹风藤、七叶一枝花、通城虎、土鳖虫、莪术、马鞭草具有活血驱邪、抗菌抑菌、保护鼻黏膜的药用,可快速、彻底地解除鼻黏膜及黏膜下层的炎症;所选中药药材穿山甲、巴戟天、丹参具有温阳补肾的药用,可增强病患的机体免疫力,减少鼻炎的复发;在本发明中利用青木香预防皮肤过敏的作用,使得本发明的治疗鼻炎的中药组合物能够适用于皮肤易于过敏人群;所选中药药材地龙起到预防咽鼓管阻塞的作用。
Description
技术领域
本发明涉及中药领域,尤其涉及治疗鼻炎的中药组合物。
背景技术
鼻炎是鼻黏膜或黏膜下组织因为病毒感染、病菌感染、刺激物刺激等,导致鼻黏膜或黏膜下组织受损,所引起的急性或慢性、急性炎症。鼻炎导致产生过多黏液,通常引起流涕、鼻塞等症状。鼻炎的症状表现与枯草热不同,常年性鼻炎的症状全年内时轻时重,通常不可预料,鼻部以外的症状(如结膜炎)不多见,但慢性、急性鼻塞通常明显,且有可能发展为咽鼓管阻塞,其结果为听力减退,甚至有的病人还会并发鼻窦感染和鼻息肉等症状。
传统治疗鼻炎疾病的方法主要有物理治疗、手术治疗、药物治疗等,但治疗的过程较长,且极易反复,难以根治。
发明内容
本发明的目的在于:针对上述存在的问题,本发明提供一种可根治慢性、急性鼻炎的内用治疗鼻炎的中药组合物。
本发明是通过以下技术方案实现的:
配方为:治疗鼻炎的中药组合物,用来制作该治疗鼻炎的中药组合物的中药药材是由以下重量份的组分组成:八角莲30~35份、蝎子30~35份、蜈蚣30~35份、穿山甲30~35份、吹风蛇500~650份、五步蛇1000~1150份、洛石藤50~55份、吹风藤45~50份、巴戟天40~45份、七叶一枝花30~35份、青木香40~45份、通城虎40~45份、土鳖虫20~25份、地龙20~25份、莪术50~55份、马鞭草50~55份、丹参45~55份。
在本发明中,进一步地,治疗鼻炎的中药组合物,用来制作该治疗鼻炎的中药组合物的中药药材是由以下重量份的组分组成:八角莲32~35份、蝎子32~35份、蜈蚣32~35份、穿山甲32~35份、吹风蛇550~650份、五步蛇1100~1150份、洛石藤51~55份、吹风藤47~50份、巴戟天44~45份、七叶一枝花32~35份、青木香43~45份、通城虎41~45份、土鳖虫22~25份、地龙22~25份、莪术52~55份、马鞭草52~55份、丹参50~55份。
在本发明中,进一步地,治疗鼻炎的中药组合物,用来制作该治疗鼻炎的中药组合物的中药药材是由以下重量份的组分组成:八角莲32份、蝎子32份、蜈蚣32份、穿山甲32份、吹风蛇550份、五步蛇1100份、洛石藤51份、吹风藤47份、巴戟天44份、七叶一枝花32份、青木香43份、通城虎41份、土鳖虫22份、地龙22份、莪术52份、马鞭草52份、丹参50份。
在本发明中,进一步地,用来制作该治疗鼻炎的中药组合物的酒是酒精度为45度~55度的酒。
制备方法为:治疗鼻炎的中药组合物的制备方法,包括以下步骤:
(1)按照配方称取制作该治疗鼻炎的中药组合物的中药药材,将中药药材中的八角莲、蝎子、蜈蚣、穿山甲、洛石藤、吹风藤、巴戟天、七叶一枝花、青木香、通城虎、土鳖虫、地龙、莪术、马鞭草、丹参晾晒干,得到干燥的中药药材;
(2)将生的吹风蛇和五步蛇洗净备用;
(3)将干燥的中药药材和洗净的吹风蛇、五步蛇共同放入干净的容器中,得到混合的中药药材;
(4)在混合的中药药材中加入酒精度为45度~55度的酒,密封浸泡25天~30天,得到浸泡后的药酒;
(5)将浸泡后的药酒过滤,去除药渣,即得所述治疗鼻炎的中药组合物。
在本发明中,进一步地,所述步骤(1)中干燥的中药药材的水分含量小于15%。
在本发明中,进一步地,所述步骤(4)中的酒与混合的中药药材的体积比为3.76~7.33:1。
在本发明中,进一步地,所述步骤(4)中在混合的中药药材中加入酒精度为50度的酒,密封浸泡28天,得到浸泡后的药酒。
八角莲,又叫金魁莲、旱八角,属于小檗科、鬼臼属植物,花期为春末,花苞由两个叶柄交叉处生出,常常是数朵簇生,花苞下垂开出紫红色花朵,其特殊盾形掌状的叶片是认识它的标记,观察是否有花苞开出,可以观察是否有两片叶子。八角莲生育环境分布于海拔1000公尺至2500公尺,常见于阴湿的阔叶林间,是民间常用的中草药,入药能散风祛痰,清热解毒,散结散瘀,杀虫,有其特殊的解毒功效,可治蛇咬伤,现已被列为国家保护植物。
蝎子,蝎子是蛛形纲动物,蜘蛛亦同属蛛形纲。它们典型的特征包括瘦长的身体、螫、弯曲分段且带有毒刺的尾巴。陆地上最早的蝎子约出现于四亿三千万年前的希留利亚纪。它具有解毒中药属性:能清理身体内长期淤积的毒素,增进身体健康。消炎止痛:舒缓疼痛,减少疼痛感。
蜈蚣,蜈蚣为陆生节肢动物,身体由许多体节组成,每一节上均长有步足,故为多足生物。又作吴公,又称百足虫、百脚虫、蝍蛆、天龙。是一种有毒腺的、掠食性的陆生节肢动物。但它的功能主治是:息风镇痉,攻毒散结,通络止痛。用于小儿惊风,抽搐痉挛,中风口歪,半身不遂,破伤风,风湿顽痹,疮疡,瘰疬,毒蛇咬伤。
穿山甲,是对穿山甲科穿山甲属的统称,共8个物种。地栖性哺乳动物,体形狭长,全身有鳞甲,四肢粗短,尾扁平而长,背面略隆起。它的药用价值是活血散结、通经下乳、消痈排脓,搜风通络。主血瘀经闭、症瘕、风湿痹痛、乳汁不下、痈肿、瘰疬。
吹风蛇,又称山万蛇、过山峰、大扁颈蛇、大眼镜蛇、大扁头风、扁颈蛇、大膨颈、眼镜王蛇、过山标等。有祛风除湿、通经活络、止痛、破血散结的功效,它的主治是用于各种疼痛症、经闭症瘕、癌症。
五步蛇,五步蛇是蛇亚目蝰蛇科蝮亚科下的一个有毒单型蛇,属下尖吻蝮的幼蛇只有尖吻蝮一个品种。五步蛇又称百步蛇、七步蛇、尖吻蝮、蕲蛇、山谷虌、百花蛇、中华蝮等,是亚洲地区内相当著名的蛇种,尤其在台湾及华南一带更是自古已备受重视的蛇类。目前未有任何亚种被确认。功能主治: 全体有通血、祛风通络、透骨搜风、定惊的功能;主治风湿瘫痪、骨节疼痛、麻风、疥癣、惊风抽搐、破伤风、杨梅疮、瘰疬恶疮等。头有泻火解毒的功能,主治白癫风、癞疮。眼睛有疏风定惊的功能。
落石藤,学名络石,又名扒墙虎,吸壁藤,万字茉莉。夹竹桃科络石属植物络石茎叶。植物形态常绿木质藤本,长达10米,具乳汁。分布很广,生于山野、溪边、路旁、林缘或杂木林中,常缠绕于树上或攀援于墙壁上、岩石上,亦有移栽于园圃,供观赏。有袪风湿、清热凉血、解毒消肿、舒筋通络功效。
吹风藤,小果微花藤,木质藤本。小枝压扁,被淡黄色硬伏毛,卷须腋生或生于叶柄的一侧,叶近对生。它能祛风散寒、除湿通络,主风寒湿痹、肾炎、劳伤。
巴戟天,为双子叶植物茜草科,长3~13cm,宽1.5~5cm,前端短渐尖,基部钝形或圆形。巴戟天的干燥根,根呈扁圆柱形,略弯曲。主产于广东、广西等地。药用植物,主治阳痿遗精、宫冷不孕、月经不调、少腹冷痛、风湿痹痛、筋骨痿软。
七叶一枝花,百合科重楼属的植物。别名蚤休、蚩休,重台根、整休、草河车、重台草、白甘遂、金线重楼、虫蒌、九道箍、鸳鸯虫、枝花头,螺丝七、海螺七、灯台七、白河车、螺陀三七、土三七,又名七叶莲。其特征是由一圈轮生的叶子中冒出一朵花,花的形状像极了它的叶子,它可以分成两个部分,外轮花及内轮花,外轮花与叶子很像,约有6片,而内轮花约有8片,七叶一枝花的叶序属轮生叶,片数有个体差异、从4片到14片都有,"七叶"只是名称。花的结构特别:叶心如轮状会开花,花萼为绿色,花瓣呈细丝带状。台湾早期用来治蛇毒与疮疡肿毒等症状。有清热解毒、消肿止痛、祛痰解咳、晾肝定惊之功效。用于疔疮肿痛、咽喉肿痛、蛇虫咬伤、跌扑伤痛、惊风抽搐。
青木香,为马兜铃科植物马兜铃的干燥根。春、秋二季采挖,除去须根及泥沙,晒干。它的功效有行气、解毒、消肿、治胸腹胀痛、痧症、肠炎下痢、高血压、疝气、蛇咬毒、痈肿、疔疮。
通城虎,别名:五虎通城、定心草、万丈藤、大散血、血蒟,马兜铃科、马兜铃属草质藤本,根圆柱形,细长;茎无毛,干后常有纵棱。叶革质或薄革质,卵状心形或卵状三角形,顶端长渐尖或短渐尖,基部心形,两侧裂片近圆形,下垂或扩展,边全缘,上面绿色,无毛,下面粉绿色仅网脉上密被茸毛,茸毛与网脉成垂直方向;蒴果长圆形或倒卵形,褐色,成熟时由基部向上6瓣开裂,果梗亦随之开裂;种子卵状三角形,褐色,背面平凸状,具小疣点,腹面凹入。花期3-4月,果期5-7月。功效:祛风、镇痛、消肿、解毒,主风湿骨痛、胃脘痛、腹痛、咽喉炎、跌打损伤、小儿惊风、毒蛇咬伤。
土鳖虫,为鳖蠊科昆虫地鳖或冀地鳖的雌虫干燥体。捕捉后,置沸水中烫死,晒干或烘干。分布于河北、陕西、甘肃、青海、山东、河南、江苏、浙江、湖南等地。具有活血散瘀、消肿止痛、续筋接骨之功效。用于跌打损伤、筋伤骨折、血瘀经闭、产后瘀阻腹痛、瘾瘕痞块。
地龙,折叠蚯蚓俗称曲蟮,中药称地龙,地龙性寒味咸。功能:主治高热狂燥、惊风抽搐、风热头痛、目赤、半身不遂等。地龙提取液有良好的定咳平喘的作用。
莪术,别称莪药、莪茂、青姜、黑心姜、姜黄,为多年生宿根草本。功效为行气破血、化瘀、消积止痛。用于燀瘕痞块、瘀血经闭、食积胀痛、早期宫颈癌。
马鞭草,马鞭草科马鞭草属植物。多年生直立草本植物,基部木质化;四方形茎;倒卵形至长椭圆形的叶子对生,边缘通常3深裂;穗状花序顶生或腋生,形状似马鞭状,夏秋间开淡紫色唇形花。马鞭草甙对交感神经末梢小量兴奋,大量抑制;马鞭草可促进哺乳动物乳汁分泌。具有清热解毒、活血散瘀、通淋利尿的功效,用于症瘕积聚、经闭痛经、疟疾、喉痹、痈肿、水肿、热淋。
丹参,又名赤参、紫丹参、红根等,为唇形科植物丹参的干燥根和根茎。春、秋二季采挖,除去泥沙,干燥。全国大部分地区都有分布。具有活血祛瘀、通经止痛、清心除烦、凉血消痈之功效。用于胸痹心痛、脘腹胁痛、瘕瘕积聚、热痹疼痛、心烦不眠、月经不调、痛经经闭、疮疡肿痛。
本发明的有益效果是:所选中药药材八角莲、蝎子、蜈蚣、吹风蛇、五步蛇、洛石藤、吹风藤、七叶一枝花、通城虎、土鳖虫、莪术、马鞭草具有活血驱邪、抗菌抑菌、保护鼻黏膜的药用,可快速、彻底地解除鼻黏膜及黏膜下层的炎症;所选中药药材穿山甲、巴戟天、丹参具有温阳补肾的药用,可增强不同年龄、不同性别、不同体质的病患的机体免疫力,减少鼻炎的复发;所选中药药材青木香自古以来人们都是利用其有行气、解毒、消肿的药用,在本发明中利用的则是它预防皮肤过敏的作用,这一作用为本发明所总结,使得本发明的治疗鼻炎的中药组合物能够适用于皮肤易于过敏人群,同时起到治疗鼻炎患者长期流鼻涕导致的皮肤瘙痒或湿烂的症状;所选中药药材地龙自古以来人们都是利用其清热、平肝、止喘的药用,在本发明中利用的则是它预防咽鼓管阻塞的作用,这一作用为本发明所总结,使得本发明的治疗鼻炎的中药组合物能够起到预防咽鼓管阻塞的作用。
具体实施方式
本说明书(包括任何附加权利要求、摘要)中公开的任一特征,除非特别叙述,均可被其他等效或具有类似目的的替代特征加以替换。即,除非特别叙述,每个特征只是一系列等效或类似特征中的一个例子而已。
实施例1:
配方为:治疗鼻炎的中药组合物,用来制作该治疗鼻炎的中药组合物的中药药材是由以下重量份的组分组成:八角莲30份、蝎子30份、蜈蚣30份、穿山甲30份、吹风蛇500份、五步蛇1000份、洛石藤50份、吹风藤45份、巴戟天40份、七叶一枝花30份、青木香40份、通城虎40份、土鳖虫20份、地龙20份、莪术50份、马鞭草50份、丹参45份,用来制作该治疗鼻炎的中药组合物的酒是酒精度为45度的酒。
制备方法为:治疗鼻炎的中药组合物的制备方法,包括以下步骤:
(1)按照配方称取制作该治疗鼻炎的中药组合物的中药药材,将中药药材中的八角莲、蝎子、蜈蚣、穿山甲、洛石藤、吹风藤、巴戟天、七叶一枝花、青木香、通城虎、土鳖虫、地龙、莪术、马鞭草、丹参晾晒干,得到干燥的中药药材,干燥的中药药材的水分含量为14%;
(2)将生的吹风蛇和五步蛇洗净备用;
(3)将干燥的中药药材和洗净的吹风蛇、五步蛇共同放入干净的容器中,得到混合的中药药材;
(4)在混合的中药药材中加入酒精度为45度的酒,密封浸泡25天,得到浸泡后的药酒,其中的酒与混合的中药药材的体积比为3.76:1;
(5)将浸泡后的药酒过滤,去除药渣,即得所述治疗鼻炎的中药组合物。
实施例2:
配方为:治疗鼻炎的中药组合物,用来制作该治疗鼻炎的中药组合物的中药药材是由以下重量份的组分组成:八角莲35份、蝎子35份、蜈蚣35份、穿山甲35份、吹风蛇650份、五步蛇1150份、洛石藤55份、吹风藤50份、巴戟天45份、七叶一枝花35份、青木香45份、通城虎45份、土鳖虫25份、地龙25份、莪术55份、马鞭草55份、丹参55份,用来制作该治疗鼻炎的中药组合物的酒是酒精度为55度的酒。
制备方法为:治疗鼻炎的中药组合物的制备方法,包括以下步骤:
(1)按照配方称取制作该治疗鼻炎的中药组合物的中药药材,将中药药材中的八角莲、蝎子、蜈蚣、穿山甲、洛石藤、吹风藤、巴戟天、七叶一枝花、青木香、通城虎、土鳖虫、地龙、莪术、马鞭草、丹参晾晒干,得到干燥的中药药材,干燥的中药药材的水分含量为13%;
(2)将生的吹风蛇和五步蛇洗净备用;
(3)将干燥的中药药材和洗净的吹风蛇、五步蛇共同放入干净的容器中,得到混合的中药药材;
(4)在混合的中药药材中加入酒精度为55度的米酒,密封浸泡30天,得到浸泡后的药酒,其中的米酒与混合的中药药材的体积比为7.33:1;
(5)将浸泡后的药酒过滤,去除药渣,即得所述治疗鼻炎的中药组合物。
实施例3:
配方为:治疗鼻炎的中药组合物,用来制作该治疗鼻炎的中药组合物的中药药材是由以下重量份的组分组成:八角莲32份、蝎子32份、蜈蚣32份、穿山甲32份、吹风蛇550份、五步蛇1100份、洛石藤51份、吹风藤47份、巴戟天44份、七叶一枝花32份、青木香43份、通城虎41份、土鳖虫22份、地龙22份、莪术52份、马鞭草52份、丹参50份。
制备方法为:治疗鼻炎的中药组合物的制备方法,包括以下步骤:
(1)按照配方称取制作该治疗鼻炎的中药组合物的中药药材,将中药药材中的八角莲、蝎子、蜈蚣、穿山甲、洛石藤、吹风藤、巴戟天、七叶一枝花、青木香、通城虎、土鳖虫、地龙、莪术、马鞭草、丹参晾晒干,得到干燥的中药药材,干燥的中药药材的水分含量为12%;
(2)将生的吹风蛇和五步蛇洗净备用;
(3)将干燥的中药药材和洗净的吹风蛇、五步蛇共同放入干净的容器中,得到混合的中药药材;
(4)在混合的中药药材中加入酒精度为50度的三花酒,密封浸泡25天~30天,得到浸泡后的药酒,其中的三花酒与混合的中药药材的体积比为4.19:1;
(5)将浸泡后的药酒过滤,去除药渣,即得所述治疗鼻炎的中药组合物。
本发明治疗鼻炎的中药组合物的临床实验过程和结果如下:
1.选取符合西医诊断的慢性鼻炎患者100例,其中成年女性25人,未成年女性25人,成年男性25人,未成年男性25人;选取符合西医诊断的急性鼻炎患者100例,其中成年女性25人,未成年女性25人,成年男性25人,未成年男性25人。
2.疗效标准为:痊愈:清涕、鼻痒消失;好转:清涕消失、鼻痒缓解;未愈:症状无变化。
3.治疗方法:未成年人每次口服5克,一天3次,50天为一疗程;成年人每次口服50克,一天3次,50天为一疗程。
本发明的临床实验100例,其中男性100例,女性100例,年龄最大55岁,最小10岁;痊愈192例,痊愈的比例为96.00%;好转6例,好转的比例为3.00%;未愈2例,未愈的比例为1.00%。
其中典型病例如下:
病例1,莫某,未成年,男,广西桂林人,11岁,有鼻塞红肿、呼吸困难,鼻涕浊症。使用本发明实施例1的药酒治疗,每天口服本药酒3次,每次5克;连续服药一个月后炎症已达到基本痊愈;连续服药两个月时痊愈,愈后无后遗症。
病例2,莫某,成年,男,过敏体质,广西桂林人,2015年初有鼻塞呼吸不畅、流鼻涕并时常伴有感冒的症状。使用本发明实施例2的药酒治疗,每天口服此药酒三次,每次50克,30天后鼻炎症状已全部消除,且服药过程中无过敏症状发生,两个月后炎症痊愈,愈后无后遗症。
病例3,李某,成年,男,广西桂林人,2006年12月出现鼻子红肿、流鼻涕、呼吸极度困难的症状。使用本发明实施例3的药酒治疗,连续性服用此药酒30天,每天3次,每次50克,鼻炎症状已基本消除;继续服用此药酒30天,每次50克,鼻炎病症痊愈,愈后无后遗症。
病例4,贲某,成年,男,广西桂林人,鼻腔堵塞、鼻流浊涕、头痛、嗅觉减退,于2008年11月开始使用本发明实施例3的药酒治疗,连续饮用此药酒两个月,每天三次,每次50克,病症便痊愈,愈后无后遗症。
病例5,李某,成年,女,过敏体质,广西桂林人,出现鼻腔堵塞、鼻流浊涕、头痛的症状,2008年12月开始使用本发明实施例3的药酒治疗,连续服用此药三个月,每天三次,每次50克, 病症便痊愈,且服药过程中无过敏症状发生,愈后无后遗症。
虽然,上文中已经用一般性说明及具体实施方案对本发明作了详尽的描述,但在本发明基础上,可以对之作一些修改或改进,这对本领域技术人员而言是显而易见的。因此,在不偏离本发明精神的基础上所做的这些修改或改进,均属于本发明要求保护的范围。
Claims (8)
1.治疗鼻炎的中药组合物,其特征在于:用来制作该治疗鼻炎的中药组合物的中药药材是由以下重量份的组分组成:八角莲30~35份、蝎子30~35份、蜈蚣30~35份、穿山甲30~35份、吹风蛇500~650份、五步蛇1000~1150份、洛石藤50~55份、吹风藤45~50份、巴戟天40~45份、七叶一枝花30~35份、青木香40~45份、通城虎40~45份、土鳖虫20~25份、地龙20~25份、莪术50~55份、马鞭草50~55份、丹参45~55份。
2.根据权利要求1所述的治疗鼻炎的中药组合物,其特征在于,用来制作该治疗鼻炎的中药组合物的中药药材是由以下重量份的组分组成:八角莲32~35份、蝎子32~35份、蜈蚣32~35份、穿山甲32~35份、吹风蛇550~650份、五步蛇1100~1150份、洛石藤51~55份、吹风藤47~50份、巴戟天44~45份、七叶一枝花32~35份、青木香43~45份、通城虎41~45份、土鳖虫22~25份、地龙22~25份、莪术52~55份、马鞭草52~55份、丹参50~55份。
3.根据权利要求1所述的治疗鼻炎的中药组合物,其特征在于,用来制作该治疗鼻炎的中药组合物的中药药材是由以下重量份的组分组成:八角莲32份、蝎子32份、蜈蚣32份、穿山甲32份、吹风蛇550份、五步蛇1100份、洛石藤51份、吹风藤47份、巴戟天44份、七叶一枝花32份、青木香43份、通城虎41份、土鳖虫22份、地龙22份、莪术52份、马鞭草52份、丹参50份。
4.根据权利要求1所述的治疗鼻炎的中药组合物,其特征在于,用来制作该治疗鼻炎的中药组合物的酒是酒精度为45度~55度的酒。
5.权利要求1~3中任意一项所述的治疗鼻炎的中药组合物的制备方法,其特征在于,包括以下步骤:
(1)按照配方称取制作该治疗鼻炎的中药组合物的中药药材,将中药药材中的八角莲、蝎子、蜈蚣、穿山甲、洛石藤、吹风藤、巴戟天、七叶一枝花、青木香、通城虎、土鳖虫、地龙、莪术、马鞭草、丹参晾晒干,得到干燥的中药药材;
(2)将生的吹风蛇和五步蛇洗净备用;
(3)将干燥的中药药材和洗净的吹风蛇、五步蛇共同放入干净的容器中,得到混合的中药药材;
(4)在混合的中药药材中加入酒精度为45度~55度的酒,密封浸泡25天~30天,得到浸泡后的药酒;
(5)将浸泡后的药酒过滤,去除药渣,即得所述治疗鼻炎的中药组合物。
6.根据权利要求5所述的治疗鼻炎的中药组合物的制备方法,其特征在于,所述步骤(1)中干燥的中药药材的水分含量小于15%。
7.根据权利要求5所述的治疗鼻炎的中药组合物的制备方法,其特征在于,所述步骤(4)中的酒与混合的中药药材的体积比为3.76~7.33:1。
8.根据权利要求5所述的治疗鼻炎的中药组合物的制备方法,其特征在于,所述步骤(4)中在混合的中药药材中加入酒精度为50度的酒,密封浸泡28天,得到浸泡后的药酒。
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