CN107837126A - A kind of lightweight can absorb hernia sticking patch and preparation method thereof - Google Patents

A kind of lightweight can absorb hernia sticking patch and preparation method thereof Download PDF

Info

Publication number
CN107837126A
CN107837126A CN201610831802.6A CN201610831802A CN107837126A CN 107837126 A CN107837126 A CN 107837126A CN 201610831802 A CN201610831802 A CN 201610831802A CN 107837126 A CN107837126 A CN 107837126A
Authority
CN
China
Prior art keywords
mesh sheet
lower floor
sustained release
arc connector
infectives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610831802.6A
Other languages
Chinese (zh)
Inventor
沈乔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FUHAN LANPU MEDICAL PRODUCT Co Ltd
Original Assignee
FUHAN LANPU MEDICAL PRODUCT Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FUHAN LANPU MEDICAL PRODUCT Co Ltd filed Critical FUHAN LANPU MEDICAL PRODUCT Co Ltd
Priority to CN201610831802.6A priority Critical patent/CN107837126A/en
Publication of CN107837126A publication Critical patent/CN107837126A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0063Implantable repair or support meshes, e.g. hernia meshes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148Materials at least partially resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2240/00Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602Type of release, e.g. controlled, sustained, slow
    • A61L2300/604Biodegradation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings

Abstract

The invention discloses a kind of lightweight to can absorb hernia sticking patch, including upper strata mesh sheet, lower floor's mesh sheet, arc connector is provided between the upper strata mesh sheet and lower floor's mesh sheet, the edge of the arc connector is connected with upper strata mesh sheet by non-absorbable thread, and arc connector bottom is connected with lower floor mesh sheet by absorbable thread;Lower floor's mesh sheet, arc connector are absorbable material;Multiple anti-infective layers of sustained release are provided with lower floor's mesh sheet, anti-infective layer is sustained and is distributed in donut, the annulus center of circle and lower floor's mesh sheet center superposition;The anti-infective layer of sustained release is by being coated with sustained release anti-infectives in lower floor's mesh sheet, and air drying forms.Arc connector and lower floor's mesh sheet are all Biodegradable materials, can be nontoxic slowly in human body metabolism, effectively can isolate the surface of a wound with internal organs, in order to avoid the surface of a wound directly contacts with surrounding tissue in agglutination, effectively prevent the generation of adhesion.

Description

A kind of lightweight can absorb hernia sticking patch and preparation method thereof
Technical field
The present invention relates to a kind of hernia patch, and hernia sticking patch and preparation method thereof is can absorb more particularly, to a kind of lightweight.
Background technology
Abdominal hernia is caused by abdominal viscera goes out via stock ventral groove rostrum, and the incidence of disease of abdominal hernia is high(Male is about 27%, female Property is about 3%), and the various ages may occur, traditional restorative procedure is because with easy recurrence, repair time is long, postoperative pain Pain etc. is determined without being used, and is arisen at the historic moment using the Hammock Method operation of sticking patch mode.Tension-free Hernioplasty is to use Sticking patch carrys out repairing hernia breach, the shortcomings that avoiding the postoperative pain of traditional herniorrhaphy, easily recur.Clinically generally adopt at present The sticking patch made of polyester, polypropylene material.
Propene polymer patch has excellent chemical stability and histocompatbility, fibr tissue can be promoted to be formed, it has Anti-infection property is good, intensity is high, biologically inert, operation easily, the advantages that being unlikely to deform, be cheap.But propene polymer patch is not Possess the function that prevents adhesion, clinically there is the case that the complication such as stomachache, intestinal fistula, material corrosion internal organ occur for implantation abdominal cavity. Therefore, design one kind is effectively isolated abdominal viscera and hernia patch, and the hernia patch with preventing adhesiving effect is necessary 's.
The content of the invention
It is an object of the present invention to provide an a kind of lightweight to can absorb hernia sticking patch and preparation method thereof, to solve existing hernia repairing hand Postoperative hernia patch can with visceral adhesion, cause multiple complications, the increase technical problem such as patient's pain.
In order to solve the above-mentioned technical problem, the technical solution adopted by the present invention is:A kind of hernia repairing of absorbent antiseize Piece, including upper strata mesh sheet, lower floor's mesh sheet, arc connector, the arc are provided between the upper strata mesh sheet and lower floor's mesh sheet The edge of connector is connected with upper strata mesh sheet by non-absorbable thread, and arc connector bottom passes through absorbable thread with lower floor's mesh sheet Connection;Lower floor's mesh sheet, arc connector are absorbable material;It is anti-infective that multiple sustained releases are provided with lower floor's mesh sheet Layer, it is sustained anti-infective layer and is distributed in donut, the annulus center of circle and lower floor's mesh sheet center superposition;The anti-infective layer of sustained release is logical Coating sustained release anti-infectives, drying in lower floor's mesh sheet is crossed to form.
Preferably, the material of the upper strata mesh sheet is single fiber polypropylene or expanded polytetrafluoroethylsealing.
Preferably, lower floor's mesh sheet, the material of arc connector are poly- carboxyl acetic acid, polylactic-co-glycolic acid, gathered Lactic acid(PLA)At least one of.
Preferably, the absorbable thread is made up of the gutstring of chitin or bag chitin film.
Preferably, the sustained release anti-infectives, including sustained release agent, anti-infectives;Sustained release agent is PLA (PLA), polyglycolic acid, polyethylene glycol(PEG), Polyhydroxybutyrate-co-hydroxyvalerate copolymer(PHBV), fibrin coagulates At least one of glue, collagen sponge, chitosan, gelatin;Anti-infectives are aminoglycoside medicaments:It is streptomysin, new mould Element, SISO;QNS:MOXIFLOXACIN, Clinafloxacin, gemifloxacin;Sugared peptide medicament:Vancomycin, impersonate Draw at least one of peaceful.
A kind of method for the hernia patch for preparing above-mentioned absorbent antiseize, comprises the following steps:
A. by the aqueous solution of anti-infectives, it is added in the organosol or the aqueous solution of sustained release agent, by being stirred, medicine Wrapped up by sustained release agent, sustained release anti-infectives are made;
B. sustained release anti-infectives are sprayed in lower floor's mesh sheet, forming annular after drying is sustained anti-infective layer;
C. lower floor's mesh sheet and arc connector bottom are sutured with absorbable thread;
D. the edge of arc connector and upper wire piece are sutured with non-absorbable thread, you can the hernia that absorbent antiseize is made is repaiied Sticking patch.
The structure that the present invention is combined using upper strata mesh sheet with arc connector, lower floor's mesh sheet, upper strata mesh sheet safety, nothing Poison, histocompatbility are good, can maintain higher tension force and belly compliance, the gap of granulation tissue progress upper strata mesh sheet can With the intensity of increase repairing, arc connection physical efficiency is filled in the duct of hernia to be bonded with peritonaeum, is easy to the regeneration of defect, lower net Piece is also coated with the sustained release that sustained release agent and anti-infectives are combined using absorbable compound mesh sheet in lower floor's mesh sheet Anti-infective layer, it can effectively avoid postoperative wound infection;Arc connector and lower floor's mesh sheet are all Biodegradable materials, energy It is nontoxic slowly in human body metabolism, effectively the surface of a wound can be isolated with internal organs, in order to avoid created in agglutination Face directly contacts with surrounding tissue, effectively prevents the generation of adhesion.The hernia patch of the absorbent antiseize of the present invention has Good anti-infective and preventing adhesiving effect, is very suitable for herniorrhaphy, can reduce postoperative complication, mitigates patient's pain.
Brief description of the drawings
In order to illustrate more clearly about the embodiment of the present invention or technical scheme of the prior art, below will be to embodiment or existing There is the required accompanying drawing used in technology description to be briefly described, it should be apparent that, drawings in the following description are only this Some embodiments of invention, for those of ordinary skill in the art, on the premise of not paying creative work, can be with Other accompanying drawings are obtained according to these accompanying drawings.
Fig. 1 is the structural representation that lightweight can absorb hernia sticking patch;
Fig. 2 is Fig. 1 top view.
Embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete Site preparation describes, it is clear that described embodiment is only part of the embodiment of the present invention, rather than whole embodiments.It is based on Embodiment in the present invention, those of ordinary skill in the art are obtained every other under the premise of creative work is not made Embodiment, belong to the scope of protection of the invention.
Fig. 1 is the structural representation that lightweight can absorb hernia sticking patch, and Fig. 2 is Fig. 1 top view.
As seen from the figure, the lightweight can absorb hernia sticking patch, including upper strata mesh sheet 1, lower floor's mesh sheet 2, arc connector 3 etc..On Be provided with arc connector 3 between layer mesh sheet 1 and lower floor's mesh sheet 2, the edge of arc connector 3 and upper strata mesh sheet 1 by it is non-can Absorption Line 4 is connected, and the bottom of arc connector 3 is connected with lower floor mesh sheet 2 by absorbable thread 5.The material of upper strata mesh sheet 1 is single fiber Polypropylene or expanded polytetrafluoroethylsealing.
Lower floor's mesh sheet 2, arc connector 3 are absorbable material.Lower floor's mesh sheet 2, the material of arc connector 3 are poly- carboxylic Guanidine-acetic acid, polylactic-co-glycolic acid, PLA(PLA)At least one of.It is anti-infective that multiple sustained releases are provided with lower floor's mesh sheet 2 Layer 6, it is sustained anti-infective layer 6 and is distributed in donut, the annulus center of circle and the center superposition of lower floor's mesh sheet 2.It is logical to be sustained anti-infective layer 6 Coating sustained release anti-infectives, drying in lower floor's mesh sheet 2 is crossed to form.
Above-mentioned absorbable thread 5 is made up of the gutstring of chitin or bag chitin film.
Above-mentioned sustained release anti-infectives, including sustained release agent, anti-infectives;Sustained release agent is PLA(PLA), PVOH Acid, polyethylene glycol(PEG), Polyhydroxybutyrate-co-hydroxyvalerate copolymer(PHBV), it is fibrin gel, collagen sponge, several At least one of fourth glycan, gelatin, anti-infectives are aminoglycoside medicaments:Streptomysin, neomycin, SISO;Quinoline Promise ketone medicine:MOXIFLOXACIN, Clinafloxacin, gemifloxacin;Sugared peptide medicament:At least one in vancomycin, teicoplanin Kind.
The method that above-mentioned lightweight can absorb hernia sticking patch is prepared, is comprised the following steps:
A. by the aqueous solution of anti-infectives, it is added in the organosol or the aqueous solution of sustained release agent, by being stirred, medicine Wrapped up by sustained release agent, sustained release anti-infectives are made;
B. sustained release anti-infectives are sprayed in lower floor's mesh sheet, forming annular after drying is sustained anti-infective layer;
C. lower floor's mesh sheet and arc connector bottom are sutured with absorbable thread;
D. the edge of arc connector and upper wire piece are sutured with non-absorbable thread, you can the hernia that absorbent antiseize is made is repaiied Sticking patch.
It is several embodiments of the hernia patch of the absorbent antiseize below.
Embodiment 1:
A kind of method for preparing lightweight and caning absorb hernia sticking patch, comprises the following steps:
S1. anti-infectives Clinafloxacin and water are pressed 1:The Clinafloxacin aqueous solution is made in 2 part by weight, by Clinafloxacin water Solution is added in the sustained release agent chitosan aqueous solution, and by being stirred, medicine is wrapped up by sustained release agent, and it is anti-infective that sustained release is made Medicine, the medicament contg for being sustained anti-infectives are 50mg/ml;
S2. sustained release anti-infectives are sprayed in lower floor's mesh sheet of poly- carboxyl acetic acid material, it is anti-that annular sustained release is formed after drying Infect layer;
S3. sutured with absorbable thread by lower floor's mesh sheet and in the arc connector bottom of poly- carboxyl acetic acid material;
S4. the edge of arc connector and the upper wire piece of polypropylene material are sutured with non-absorbable thread, you being made to inhale Receive the hernia patch to prevent adhesion.
Embodiment 2:
A kind of method for preparing lightweight and caning absorb hernia sticking patch, comprises the following steps:
S1. anti-infectives vancomycin and water are pressed 1:The vancomycin aqueous solution is made in 2 part by weight, by vancomycin water Solution is added in the organosol of sustained release agent polyethylene glycol, and by being stirred, medicine is wrapped up by sustained release agent, and it is anti-that sustained release is made Infection medicine, the medicament contg for being sustained anti-infectives are 65mg/ml;
S2. sustained release anti-infectives are sprayed in lower floor's mesh sheet of PLA material, it is anti-infective that annular sustained release is formed after drying Layer;
S3. the arc connector bottom of lower floor's mesh sheet and poly- carboxyl acetic acid material is sutured with absorbable thread;
S4. the edge of arc connector and the upper wire piece of polypropylene material are sutured with non-absorbable thread, you being made to inhale Receive the hernia patch to prevent adhesion.
Embodiment 3:
A kind of method for preparing lightweight and caning absorb hernia sticking patch, comprises the following steps:
S1. anti-infectives neomycin and water are pressed 1:The neomycin aqueous solution is made in 3 part by weight, and the neomycin aqueous solution is added Enter into the organosol of sustained release agent PLA, by being stirred, medicine is wrapped up by sustained release agent, and sustained release anti-infectious agent is made Thing, the medicament contg for being sustained anti-infectives are 80mg/ml;
S2. sustained release anti-infectives are sprayed in lower floor's mesh sheet of polylactic-co-glycolic acid material, it is slow to form annular after drying Release anti-infective layer;
S3. the arc connector bottom of lower floor's mesh sheet and polylactic-co-glycolic acid material is sutured with absorbable thread;
S4. the edge of arc connector and the upper wire piece of polypropylene material are sutured with non-absorbable thread, you being made to inhale Receive the hernia patch to prevent adhesion.
In the present invention, lower floor's mesh sheet using absorbable compound mesh sheet, be also coated with lower floor's mesh sheet sustained release agent and The anti-infective layer of sustained release that anti-infectives are combined, can effectively avoid postoperative wound infection;Arc connector and lower floor Mesh sheet is all Biodegradable material, can be nontoxic slowly in human body metabolism, can be effectively by the surface of a wound and internal organs Isolated, in order to avoid the surface of a wound directly contacts with surrounding tissue in agglutination, effectively prevent the generation of adhesion.
Finally it is pointed out that above embodiment is only the more representational example of the present invention.Obviously, it is of the invention Above-mentioned embodiment is not limited to, there can also be many deformations.Every technical spirit according to the present invention specific reality to more than Any simple modification, equivalent change and modification that the mode of applying is made, it is considered as belonging to protection scope of the present invention.

Claims (6)

1. a kind of hernia patch of absorbent antiseize, including upper strata mesh sheet, lower floor's mesh sheet, it is characterized in that the upper strata mesh sheet with Arc connector is provided between lower floor's mesh sheet, the edge of the arc connector is connected with upper strata mesh sheet by non-absorbable thread Connect, arc connector bottom is connected with lower floor mesh sheet by absorbable thread;Lower floor's mesh sheet, arc connector are absorbable Material;Multiple anti-infective layers of sustained release are provided with lower floor's mesh sheet, anti-infective layer is sustained and is distributed in donut, the annulus center of circle With lower floor's mesh sheet center superposition;The anti-infective layer of sustained release is by being coated with sustained release anti-infectives in lower floor's mesh sheet, drying Form.
2. the hernia patch of absorbent antiseize according to claim 1, it is characterized in that the material of the upper strata mesh sheet is Single fiber polypropylene or expanded polytetrafluoroethylsealing.
3. the hernia patch of absorbent antiseize according to claim 1, it is characterized in that lower floor's mesh sheet, arc connect The material of body is poly- carboxyl acetic acid, polylactic-co-glycolic acid, PLA(PLA)At least one of.
4. the hernia patch of absorbent antiseize according to claim 1, it is characterized in that the absorbable thread is chitin Or the gutstring of bag chitin film is made.
5. the hernia patch of absorbent antiseize according to claim 1, it is characterized in that the sustained release anti-infectives, bag Include sustained release agent, anti-infectives;Sustained release agent is PLA(PLA), polyglycolic acid, polyethylene glycol(PEG), poly butyric ester- Hydroxyl pentanoate copolymer(PHBV), fibrin gel, collagen sponge, chitosan, at least one of gelatin;It is anti-infective Medicine is aminoglycoside medicaments:Streptomysin, neomycin, SISO;QNS:MOXIFLOXACIN, Clinafloxacin, Ji Meter Sha Xing;Sugared peptide medicament:At least one of vancomycin, teicoplanin.
6. a kind of method for preparing lightweight and caning absorb hernia sticking patch, comprises the following steps:
A. by the aqueous solution of anti-infectives, it is added in the organosol or the aqueous solution of sustained release agent, by being stirred, medicine Wrapped up by sustained release agent, sustained release anti-infectives are made;
B. sustained release anti-infectives are sprayed in lower floor's mesh sheet, forming annular after drying is sustained anti-infective layer;
C. lower floor's mesh sheet and arc connector bottom are sutured with absorbable thread;
D. the edge of arc connector and upper wire piece are sutured with non-absorbable thread, you can the hernia repairing that can be prevented adhesion is made Piece.
CN201610831802.6A 2016-09-20 2016-09-20 A kind of lightweight can absorb hernia sticking patch and preparation method thereof Pending CN107837126A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610831802.6A CN107837126A (en) 2016-09-20 2016-09-20 A kind of lightweight can absorb hernia sticking patch and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610831802.6A CN107837126A (en) 2016-09-20 2016-09-20 A kind of lightweight can absorb hernia sticking patch and preparation method thereof

Publications (1)

Publication Number Publication Date
CN107837126A true CN107837126A (en) 2018-03-27

Family

ID=61656438

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610831802.6A Pending CN107837126A (en) 2016-09-20 2016-09-20 A kind of lightweight can absorb hernia sticking patch and preparation method thereof

Country Status (1)

Country Link
CN (1) CN107837126A (en)

Similar Documents

Publication Publication Date Title
US11970798B2 (en) Gripping fabric coated with a bioresorbable impenetrable layer
JP4619789B2 (en) Sealant for skin and other tissues
US9968714B2 (en) Biodegradable elastomeric patch for treating cardiac or cardiovascular conditions
US10022477B2 (en) Composition for anti-adhesion, surgical mesh composite with anti-adhesion property comprising the same and method for producing thereof
CN102266592B (en) Hydrogel implant with varying degrees of crosslinking
AU2005277591B2 (en) Anti-adhesion barrier
US20170135796A1 (en) Methods and compositions for promoting the structural integrity of scaffolds for tissue engineering
CN101932344B (en) Surgical barriers having adhesion inhibiting properties
KR101360942B1 (en) Cell-laden biocompatible polymer-natural biocompatible material hybrid scaffold and producing method therof
US20100015868A1 (en) Reinforced composite implant
TW201726997A (en) Warp-knitted fabric and medical material
BR112020022235A2 (en) 2d and 3d extracellular biomatrix structural unit and tissue structure design and manufacturing methods
CA2734336C (en) Acellular matrix glue
CN109125799A (en) GelMA hydrogel people takes off the preparation method of the three-dimensional double-deck auxiliary material of cell amnion
JP4168740B2 (en) Collagen artificial blood vessel
CN209136976U (en) One kind prevents adhesion hernia patch
CN107837126A (en) A kind of lightweight can absorb hernia sticking patch and preparation method thereof
CN106344206A (en) Absorbable anti-adhesion hernia repairing patch and preparation method thereof
CN117715665A (en) Photocurable enhancement of 3D printed hydrogel objects
JP5927061B2 (en) Sheet hemostatic material
Parin et al. Electrospun porous biobased polymer mats for biomedical applications
US20170281326A1 (en) Hernia repair device and methods
KR101436615B1 (en) Surgical mesh composite with anti-adhesion property and method for producing the same
US20210060214A1 (en) Electrospun anti-adhesion barrier
KR102665509B1 (en) Warp-knitted fabric and medical material

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20180327

WD01 Invention patent application deemed withdrawn after publication