CN107823313A - A kind of new medicine composition for treating contusion and fracture of rib and preparation method thereof - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to a kind of new medicine composition treated and dampened with fracture of rib be provided according to the understanding mechanism of Chinese traditional treatment contusion and fracture of rib, each component and its mass parts ratio of the Chinese medicine composition are as follows：80~160g of peach kernel, 30~120g of radix bupleuri, 100~160g of root of Chinese trichosanthes, 50~150g of safflower, 80~160g of Radix Angelicae Sinensis tail, 30~120g of Ligusticum wallichii, 30~100g of pangolin, 60~160g of the radix paeoniae rubrathe, 50~160g of the root of bidentate achyranthes, 50~160g of the red sage root, 30~350g of rheum officinale, 30~100g of Fructus Aurantii, 50~100g of balloonflower root, 80~160g of corydalis tuber, 3~6g of Semen Strychni (processed), 30~120g of the banksia rose, 30~150g of radix glycyrrhizae, 50~120g of safflower, 90~160g of radix rehmanniae recen, 50~100g of cortex acanthopanacis, medicine provided by the invention are a good Chinese prescriptions.

Description

A kind of new medicine composition for treating contusion and fracture of rib and preparation method thereof

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of treat is dampened and the combination of the new medicine of fracture of rib Thing, the particularly field for dampening the new medicine composition used with fracture of rib patient and preparation method thereof.

Background technology

Motherland's medical science thinks：Totally 12 pairs of rib, divide equally in chest both sides, it is preceding with breastbone, be afterwards connected with thoracic vertebrae, form one Complete pin is wide.During thoracic injury, either closed injury or open injury, fracture of rib is most commonly seen, accounts for thorax The 90% of fracture.In children, rib high resilience, it is not easily broken, and is being grown up, especially the elderly, rib elasticity weakens, and holds Easily fracture.

Clinical manifestation：

A. local pain is the most obvious symptom of fracture of rib, and moves and aggravate, have with cough, deep breathing or body rotations etc. When patient oneself can hear or feel bone abrasive feel.

B. pain and thorax stability are damaged, and can be limited Breathing movement, and tachypnea and alveolar ventilation are reduced, and are suffered from Person dare not cough, phlegm retention, and so as to cause lower respiratory tract secretion to block, pulmonary consolidation or atelectasis, this is in the old and the weak patient or original The patient for having Pulmonary Diseases should give attention especially.

C. when air-breathing in the presence of flail chest, intrathoracic negative pressure increase, the softening part wall of the chest caves inward；During expiration, thoracic cavity Pressure increases, and the wall of the chest of damage floats protrusion, and this motion with other wall of the chest is on the contrary, be referred to as " abnormal breathing ", abnormality is exhaled Inhaling motion can make both sides pleural pressure uneven, and mediastinum moves back and forth to the left and right with breathing, is referred to as " pendular movement of mediastinum ", influences blood Liquid flows back, and causes circulatory function disorderly, is one of an important factor for causing and aggravates to suffer a shock.

So, it is art technology with regard to how to find a kind of Chinese medicine composition that can effectively treat contusion and fracture of rib The problem of personnel are urgently to be resolved.

The content of the invention

With the continuous development of China's traditional Chinese medicine, dampened in treatment with fracture of rib, people gradually appreciate The advantages of Chinese traditional treatment contusion and fracture of rib, and good effect, advantage, the pin such as quick, toxic side effect is small over the course for the treatment of Existing western medical treatment is dampened and the present situation of fracture of rib, the purpose of the present invention are to be that providing one kind treats contusion and rib bone The new medicine composition of folding, got well early with fracture of rib patient with solving the problems, such as to dampen.The medicine is with common Chinese medicine be raw material, by selecting rational medicine and mass parts ratio, can effectively treat above-mentioned contusion and fracture of rib.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：One kind is provided and treats contusion and rib New medicine composition of fracture and preparation method thereof, it is characterised in that each component and mass parts of the Chinese medicine composition Than as follows：

80~160g of peach kernel, 30~120g of radix bupleuri, 100~160g of root of Chinese trichosanthes, 50~150g of safflower, 80~160g of Radix Angelicae Sinensis tail, river 30~120g of rhizome of chuanxiong, 30~100g of pangolin, 60~160g of the radix paeoniae rubrathe, 50~160g of the root of bidentate achyranthes, 50~160g of the red sage root, rheum officinale 30~ 350g, 30~100g of Fructus Aurantii, 50~100g of balloonflower root, 80~160g of corydalis tuber, 3~6g of Semen Strychni (processed), 30~120g of the banksia rose, radix glycyrrhizae 30~150g, 50~120g of safflower, 90~160g of radix rehmanniae recen, 50~100g of cortex acanthopanacis, auxiliary material：Superfine silica gel powder, microcrystalline cellulose It is appropriate with starch.

A kind of new medicine composition for treating contusion and fracture of rib and preparation method thereof, it is characterised in that in described The each component and mass parts of drug composition are than as follows：

90~140g of peach kernel, 38~105g of radix bupleuri, 115~140g of root of Chinese trichosanthes, 58~130g of safflower, 90~140g of Radix Angelicae Sinensis tail, river 38~105g of rhizome of chuanxiong, 38~90g of pangolin, 70~140g of the radix paeoniae rubrathe, 58~140g of the root of bidentate achyranthes, 58~140g of the red sage root, 38~310g of rheum officinale, 38~90g of Fructus Aurantii, 58~90g of balloonflower root, 90~140g of corydalis tuber, 4~5g of Semen Strychni (processed), 38~105g of the banksia rose, radix glycyrrhizae 38~ 130g, 58~105g of safflower, 100~140g of radix rehmanniae recen, 58~90g of cortex acanthopanacis, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and shallow lake Appropriate powder.

A kind of new medicine composition for treating contusion and fracture of rib and preparation method thereof, it is characterised in that in described The each component and mass parts of drug composition are than as follows：

Peach kernel 120g, radix bupleuri 95g, root of Chinese trichosanthes 120g, safflower 115g, Radix Angelicae Sinensis tail 120g, Ligusticum wallichii 95g, pangolin 80g, the radix paeoniae rubrathe 120g, root of bidentate achyranthes 120g, red sage root 120g, rheum officinale 280g, Fructus Aurantii 80g, balloonflower root 80g, corydalis tuber 120g, Semen Strychni (processed) 4.5g, the banksia rose 95g, radix glycyrrhizae 115g, safflower 95g, radix rehmanniae recen 120g, cortex acanthopanacis 80g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

A kind of new medicine composition for treating contusion and fracture of rib and preparation method thereof, it is characterised in that the side Method comprises the following steps to be prepared：

A, after above-mentioned raw materials Chinese medicine being picked into impurity and dust, it is ground into according to mass parts than altogether（30~50 mesh）Graininess bag Decoct；

B, 1. the raw material Chinese medicine wrapped is put into cold boiling water and soaks 60min, then soaked medicine is put into marmite again, The cold boiling water for adding 7~9 times of raw material Chinese medicine weight carries out first time high heat decoction, when 18min is arrived in decoction, turns slow fire and boils 120min, leaching decoction；2. the cold boiling water for adding 6~8 times of raw material Chinese medicine weight in the dregs of a decoction again is fried by intense fire for the second time Boil, when 15min is arrived in decoction, turn slow fire and boil 110min, leaching decoction；3. decoction mixing twice is condensed into relative density is 1.08 clear cream, then dry, grind and sterilize after it is standby；

C, the method for 1. preparing Chinese medicine capsules according to tradition, after smalls sieving ground in B, appropriate micro mist silicon is added Glue, microcrystalline cellulose and starch are well mixed, and are then prepared into capsule（Total length is 23.3mm after its capsule is sealed, medicinal powder Capacity 0.4~0.5g/ grains）, 2. then polish, sterilize, sealed packaging.

A kind of new medicine composition for treating contusion and fracture of rib and preparation method thereof, it is characterised in that the clothes It is with method：By the capsule medicine prepared three times a day to take, once a dose in the morning, afternoon and evening, dosage 3g（6）/ time, Warm water delivery service, 15 days are a course for the treatment of, and 3~6 courses for the treatment of of taking medicine, symptom disappears, and disease obtains recovery from illness.

Each raw material Chinese medicine in prescription of the present invention has in detail in Chinese Pharmacopoeia, Chinese medicine voluminous dictionary and China's book on Chinese herbal medicine Thin record.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

Peach kernel, nature and flavor：Bitter sweet, put down, it is nontoxic, there is the effect of blood-breaking row stasis of blood, moisturize laxation, for treating Amenorrhea, Disorder lumps in the abdomen, pyreticosis Store blood, wandering arthritis, malaria, traumatic injury, blood stasis and swelling pain, the dry constipation of blood；

Radix bupleuri, nature and flavor：Bitter, pungent, cold nature, there is inducing diaphoresis to bring down a fever, soothing liver-qi stagnation, rise the effect of lifting yang-energy, it is outer for treating Feel heating, fevers and chills alternate, malaria, liver-depressed hypochondrium pain mammary swelling, have a headache a dizzy, irregular menstruation, the prolapse of the anus of collapse from qi deficiency, the prolapse of uterus, The diseases such as gastroptosis；

Root of Chinese trichosanthes, nature and flavor：Cold nature, sweet, slight bitter, there are clearing heat and promoting fluid, detumescence and apocenosis.Belong to the heat-clearing of antipyretic subordinate classification Chinese laxative drugs for removing fire factor, for treating pyreticosis polydipsia, lung-heat type cough, Heat Diabetes, sore swollen toxin；

Safflower, nature and flavor：It is acrid flavour, warm-natured, there is the effect of promoting blood circulation can be through, stasis-dispelling and pain-killing, for treating Amenorrhea, dysmenorrhoea, the postpartum stasis of blood The diseases such as resistance stomachache, born of the same parents' numbness pained a lump in the abdomen causing distension and pain, traumatic injury, arthralgia, middle windage yaw are completed, macula；

Radix Angelicae Sinensis tail, nature and flavor：It is sweet, pungent, warm, there is replenishing and activating blood, menstruction regulating and pain relieving, the effect of relaxing bowel, withered for treating the deficiency of blood Huang, dizziness palpitaition, irregular menstruation, closed dysmenorrhea, asthenia cold abdominalgia, dry constipation of intestines, arthralgia pain due to rheumatism, injury from falling down, ulcer sores, wine Radix Angelicae Sinensis invigorate blood circulation.For closed dysmenorrhea, arthralgia pain due to rheumatism, injury from falling down；

Ligusticum wallichii, nature and flavor：It is acrid flavour, warm-natured, there is the effect of promoting blood circulation, promote breath and open depression, wind-expelling pain-stopping, for treating menstruation not The stagnant raw meat pain of tune, closed dysmenorrhea, the postpartum stasis of blood, abdominal mass lump, pain in chest and hypochondrium, dizziness of having a headache, wind-cold-dampness arthralgia, traumatic injury, ulcer sore Ulcer；

Pangolin, nature and flavor：Taste is salty, cold nature, have blood circulation promoting and dispersing pathogen accumulation, stimulate the menstrual flow it is lower breast, anti-stain in solid the effect of, for controlling blood The diseases such as stasis of blood Amenorrhea, Disorder lumps in the abdomen, arthralgia pain due to rheumatism, agalactia, carbuncle swells, scrofula；

The radix paeoniae rubrathe, nature and flavor：It is bitter, be slightly cold, there is the effect of clearing heat and cooling blood, promoting blood circulation, for treat febrile virulent maculae, hematemesis and epistaxis, Discharging fresh blood stool, red eye, swell pain, carbuncle swells sore, amenorrhoea, dysmenorrhoea, collapse band stranguria with turbid discharge, the stagnant hypochondriac pain of the stasis of blood, hernia lump in the abdomen accumulation, injury from falling down；

The root of bidentate achyranthes, nature and flavor：It is bitter, sour, mild-natured, there is filling liver kidney, strengthening the bones and muscles, invigorate blood circulation, draw enemy state（Fire）Descending, inducing diuresis for treating strangurtia it Effect, for treat soreness of waist and knee joint, flaccidity and weakness of the lower limbs, amenorrhea due to stagnation of blood, dysmenorrhoea, postpartum abdominal pain due to blood stasis, sign lump in the abdomen, placenta retension, heat gonorrhea, Blood strangury, traumatic injury, Carbuncle swells dislikes sore, abscess of throat；

The red sage root, nature and flavor：Bitter, cold nature, there is the effect of promoting blood circulation, menstruction regulating and pain relieving, nourishing blood and tranquilization, cool blood to disappear carbuncle, be used for Treat menoxenia, dysmenorrhoea, Amenorrhea, postpartum stasis of blood, trusted subordinate's pain, lumps in the chest and abdomen, the swelling and pain of hot numbness, traumatic injury, Heat enters ying blood, dysphoria, vexed insomnia, ulcerative carbuncle pyogenic infections；

Rheum officinale, nature and flavor：It is bitter, cold, there is the effect of rushing down real heat, broken stagnant, row hemostasis, for treating real heat constipation, dyspepsia is stagnated, Stomachache, acute appendicitis, acute infectious hepatitis, blood stasis, toothache, bleeding from five sense organs or subcutaneous tissue, acute conjunctivitis, external application are controlled burn and scald, changed Purulence skin disease, carbuncle swells sore；

Fructus Aurantii, nature and flavor：Bitter, acid, cold nature, there is the effect of wide chest of qi-regulating, row stagnant disperse accumulations, for treating septum pectorale feeling of fullness, side of body rib The disease such as weight, prolapse of the anus, prolapse of uterus after distending pain, accumulation of food in the stomach and intes tine due to indigestion, abdominal fullness and distention, diarrhea；

Balloonflower root, nature and flavor：It is mild-natured, bitter, pungent, it is slightly poisonous, there is eliminating the phlegm, relieving sore-throat, facilitaing lung, apocenosis, relieving the five internal organs, fill blood, mend five Labor, the effect of fostering the spirit of nobility, for treat abscess of throat, lung carbuncle pyemesis, coughing with a lot of sputum, dysentery stomachache, the full hypochondriac pain of born of the same parents, aphthae, The illnesss such as Akamu swelling and pain, uroschesis；

Corydalis tuber, nature and flavor：Acrid, bitter, warm, it is nontoxic, there is promoting blood circulation, dissipate the effect of stasis of blood, qi-regulating, analgesic, for treating trusted subordinate's waist and knee The diseases such as all pains, irregular menstruation, abdominal mass, metrorrhagia, postpartum anemic fainting, lochiorrhagia, traumatic injury；

Semen Strychni (processed), nature and flavor：It is bitter, cold in nature, big poison, there is the effect of dredging collateral, strengthening tendons, dissipating bind, analgesic, detumescence, removing toxic substances, for controlling Treat arthralgia pain due to rheumatism, numbness, quadriplegia, traumatic injury, fracture swelling and pain, skin sore, larynx numbness, toothache, pestilential wind, stubborn dermatitis, The diseases such as malignant tumour；

The banksia rose, nature and flavor：It is pungent acrid flavour, hardship, warm-natured, there is promoting qi circulation and relieving pain, adjust in lead the effect of stagnant, for treat born of the same parents coerce turgor foot, Weight after abdominal distention, vomiting and having loose bowel, dysentery；

Radix glycyrrhizae, nature and flavor：It is sweet, flat, have invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription the effect of, use Swollen in treatment burnout deficiency of food, the thin face Huang of flesh, palpitation, stomachache loose stool, four limbs contraction, hysteria, cough and asthma, throat Bitterly, ulcerative carbuncle swelling and pain, infant fetal toxin and medicine, food poisoning；

Safflower, nature and flavor：It is acrid flavour, warm-natured, there is the effect of promoting blood circulation can be through, stasis-dispelling and pain-killing, for treating Amenorrhea, dysmenorrhoea, the postpartum stasis of blood The diseases such as resistance stomachache, born of the same parents' numbness pained a lump in the abdomen causing distension and pain, traumatic injury, arthralgia, middle windage yaw are completed, macula；

Radix rehmanniae recen：Nature and flavor：It is sweet, cold, there is the effect of clearing heat and cooling blood, yin-nourishing, promote the production of body fluid, for treating the deep red polydipsia of pyreticosis tongue, the deficiency of Yin Interior heat, hectic fever due to yin labor heat, Heat Diabetes, spits blood, bleeding from five sense organs or subcutaneous tissue, the disease such as spot dermexanthesis；

Cortex acanthopanacis, nature and flavor；Acrid, bitter, warm, there is the effect of wind-damp dispelling, filling liver kidney, strengthening the bones and muscles, for treating arthralgia pain due to rheumatism, muscles and bones The diseases such as impotence is soft, children's retardation of walking, physically weak weak, oedema, tinea pedis.

Medicine of the present invention is the principle based on Chinese traditional treatment contusion and fracture of rib, from according to the disease dampened with fracture of rib Reason mechanism and pharmacological action are thought：With regard to contusion and fracture of rib, each raw material herbal medicine efficacy in medicine provided by the present invention is total to Play, have good effect to above-mentioned disease.

Embodiment

A kind of Chinese medicine preparation that the present invention proposes aiming at above-mentioned contusion and the treatment of fracture of rib, using the formula The medicine effect of preparation is good, quick, is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the present invention Embodiment be described in further detail：

Embodiment 1：

It is a kind of to treat the new medicine composition dampened with fracture of rib, it is characterised in that each group of the Chinese medicine composition Divide and mass parts are than as follows：

Peach kernel 120g, radix bupleuri 95g, root of Chinese trichosanthes 120g, safflower 115g, Radix Angelicae Sinensis tail 120g, Ligusticum wallichii 95g, pangolin 80g, the radix paeoniae rubrathe 120g, root of bidentate achyranthes 120g, red sage root 120g, rheum officinale 280g, Fructus Aurantii 80g, balloonflower root 80g, corydalis tuber 120g, Semen Strychni (processed) 4.5g, the banksia rose 95g, radix glycyrrhizae 115g, safflower 95g, radix rehmanniae recen 120g, cortex acanthopanacis 80g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

Embodiment 2：

It is a kind of to treat the new medicine composition dampened with fracture of rib, it is characterised in that each group of the Chinese medicine composition Divide and mass parts are than as follows：

Peach kernel 140g, radix bupleuri 105g, root of Chinese trichosanthes 140g, safflower 130g, Radix Angelicae Sinensis tail 140g, Ligusticum wallichii 105g, pangolin 90g, the radix paeoniae rubrathe 140g, root of bidentate achyranthes 140g, red sage root 140g, rheum officinale 310g, Fructus Aurantii 90g, balloonflower root 90g, corydalis tuber 140g, Semen Strychni (processed) 5g, the banksia rose 105g, radix glycyrrhizae 130g, safflower 105g, radix rehmanniae recen 140g, cortex acanthopanacis 90g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and starch are fitted Amount.

Embodiment 3：

It is a kind of to treat the new medicine composition dampened with fracture of rib, it is characterised in that each group of the Chinese medicine composition Divide and mass parts are than as follows：

Peach kernel 160g, radix bupleuri 120g, root of Chinese trichosanthes 160g, safflower 150g, Radix Angelicae Sinensis tail 160g, Ligusticum wallichii 120g, pangolin 100g, the radix paeoniae rubrathe 160g, root of bidentate achyranthes 160g, red sage root 160g, rheum officinale 350g, Fructus Aurantii 100g, balloonflower root 100g, corydalis tuber 160g, Semen Strychni (processed) 6g, the banksia rose 120g, radix glycyrrhizae 150g, safflower 120g, radix rehmanniae recen 160g, cortex acanthopanacis 100g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and starch are fitted Amount.

Model case

Dampened through clinical conditions and fracture of rib patient totally 1750, age are 970, only 780 of more than 51 years old For less than 51 years old.935 to be fully recovered in 1750 patients, effective 736, invalid 79.Total effective rate is up to 95.5%.

Claims (3)

1. it is a kind of treat dampen and fracture of rib new medicine composition, it is characterised in that the Chinese medicine composition it is each Component and its mass parts are than as follows：

80~160g of peach kernel, 30~120g of radix bupleuri, 100~160g of root of Chinese trichosanthes, 50~150g of safflower, 80~160g of Radix Angelicae Sinensis tail, river 30~120g of rhizome of chuanxiong, 30~100g of pangolin, 60~160g of the radix paeoniae rubrathe, 50~160g of the root of bidentate achyranthes, 50~160g of the red sage root, rheum officinale 30~ 350g, 30~100g of Fructus Aurantii, 50~100g of balloonflower root, 80~160g of corydalis tuber, 3~6g of Semen Strychni (processed), 30~120g of the banksia rose, radix glycyrrhizae 30~150g, 50~120g of safflower, 90~160g of radix rehmanniae recen, 50~100g of cortex acanthopanacis, auxiliary material：Superfine silica gel powder, microcrystalline cellulose It is appropriate with starch.

2. treatment according to claim 1 is dampened and the new medicine composition of fracture of rib, it is characterised in that in described The each component and its mass parts of drug composition are than as follows：

90~140g of peach kernel, 38~105g of radix bupleuri, 115~140g of root of Chinese trichosanthes, 58~130g of safflower, 90~140g of Radix Angelicae Sinensis tail, river 38~105g of rhizome of chuanxiong, 38~90g of pangolin, 70~140g of the radix paeoniae rubrathe, 58~140g of the root of bidentate achyranthes, 58~140g of the red sage root, 38~310g of rheum officinale, 38~90g of Fructus Aurantii, 58~90g of balloonflower root, 90~140g of corydalis tuber, 4~5g of Semen Strychni (processed), 38~105g of the banksia rose, radix glycyrrhizae 38~ 130g, 58~105g of safflower, 100~140g of radix rehmanniae recen, 58~90g of cortex acanthopanacis, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and shallow lake Appropriate powder.

3. the treatment according to claim 1 to 2 is dampened and the new medicine composition of fracture of rib, it is characterised in that institute The each component and its mass parts of Chinese medicine composition are stated than as follows：

Peach kernel 120g, radix bupleuri 95g, root of Chinese trichosanthes 120g, safflower 115g, Radix Angelicae Sinensis tail 120g, Ligusticum wallichii 95g, pangolin 80g, the radix paeoniae rubrathe 120g, root of bidentate achyranthes 120g, red sage root 120g, rheum officinale 280g, Fructus Aurantii 80g, balloonflower root 80g, corydalis tuber 120g, Semen Strychni (processed) 4.5g, the banksia rose 95g, radix glycyrrhizae 115g, safflower 95g, radix rehmanniae recen 120g, cortex acanthopanacis 80g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.