CN107519409A - A kind of capsule medicine and preparation method for being used to treat acne rosacea - Google Patents

A kind of capsule medicine and preparation method for being used to treat acne rosacea Download PDF

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CN107519409A
CN107519409A CN201710870605.XA CN201710870605A CN107519409A CN 107519409 A CN107519409 A CN 107519409A CN 201710870605 A CN201710870605 A CN 201710870605A CN 107519409 A CN107519409 A CN 107519409A
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medicine
radix
acne rosacea
chinese
jacq
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罗倩茹
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Sichuan Juhao Biotechnology Co Ltd
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Sichuan Juhao Biotechnology Co Ltd
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of capsule medicine for being used to treat acne rosacea provided according to the understanding mechanism of Chinese traditional treatment acne rosacea, each component and its mass parts ratio of the medicine are as follows:100~250g of cape jasmine, 30~120g of radix scutellariae, 250~550g of rust-coloured crotalaria herb with root, 80~160g of peach kernel, 80~160g of Radix Angelicae Sinensis, 30~80g of Chinese trumpet creeper, 30~100g of Ligusticum wallichii, 50~120g of safflower, 100~160g of folium isatidis, 60~100g of loguat leaf, 90~160g of radix scrophulariae, 150~360g of Ludwigia octovalvis (Jacq.) Raven, 50~100g of ox, 150~360g of reed rhizome, 100~260g of honeysuckle, medicine provided by the invention are a good Chinese prescriptions.

Description

A kind of capsule medicine and preparation method for being used to treat acne rosacea
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of capsule medicine for being used to treat acne rosacea, particularly The capsule medicine used for brandy nose patient and the field of preparation method.
Background technology
Shown according to documents and materials:Brandy nose is also known as acne rosacea, acne rosacea, and its definite cause of disease is unclear, and many factors are all It is possible to induce or aggravates disease, including the easypro contracting nervous disorder of local vascular, demodex folliculorum and local repeated infection, practical pungent food Thing, drink, caloric stimulation, stress, excited, endocrine dysfunction etc..Brandy nose mostly occurs in nose accuracy and nose Both sides, a kind of thickening brandy nose being characterized is increased with flush, papule, warts, or even nose, this sick Chang Bingfa is seborrheica Dermatitis.There is red small papule, papulo-vesicle and warts in early stage nose, and nose capillary injection is serious, and naked eyes are visible obvious There is pachydermatosis, occur the tubercle to differ in size and rough hyperplasia, nose on nose in dendritic capillary branch, late period It is sub loose uncomfortable, have a strong impact on the vivid attractive in appearance and mental health of patient.Doctor trained in Western medicine is more at present is controlled inflammation with antibiotic, and for Ill more than two months patient does the operation of brandy nose cut, but surgery side effect is big, and costly.
So, just how to find a kind of Chinese medicine composition that can effectively treat brandy nose, be those skilled in the art urgently Solve the problems, such as.
The content of the invention
With the continuous development of China's traditional Chinese medicine, on treatment brandy nose, people gradually appreciate Chinese traditional treatment The advantages of brandy nose, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment wine The present situation of slag nose, the purpose of the present invention is to be to provide a kind of capsule medicine for being used to treat acne rosacea, to solve brandy nose The problem of patient gets well early.The medicine is using common Chinese medicine as raw material, by selecting rational medicine and its quality Part ratio, can effectively treat above-mentioned brandy nose.
To reach the purpose of foregoing invention, the technical solution adopted in the present invention is:There is provided a kind of for treating acne rosacea Capsule medicine and preparation method, it is characterised in that each component and its mass parts of the medicine are than as follows:
100~250g of cape jasmine, 30~120g of radix scutellariae, 250~550g of rust-coloured crotalaria herb with root, 80~160g of peach kernel, 80~160g of Radix Angelicae Sinensis, reach the clouds Spend 30~80g, 30~100g of Ligusticum wallichii, 50~120g of safflower, 100~160g of folium isatidis, 60~100g of loguat leaf, radix scrophulariae 90~ 160g, 150~360g of Ludwigia octovalvis (Jacq.) Raven, 50~100g of ox, 150~360g of reed rhizome, 100~260g of honeysuckle, auxiliary material:Micro mist silicon Glue, microcrystalline cellulose and appropriate starch.
A kind of capsule medicine and preparation method for being used to treat acne rosacea, it is characterised in that each group of the medicine Divide and its mass parts are than as follows:
115~220g of cape jasmine, 38~105g of radix scutellariae, 280~480g of rust-coloured crotalaria herb with root, 90~130g of peach kernel, 90~130g of Radix Angelicae Sinensis, reach the clouds Spend 38~70g, 38~90g of Ligusticum wallichii, 58~105g of safflower, 115~130g of folium isatidis, 68~90g of loguat leaf, radix scrophulariae 100~ 130g, 180~320g of Ludwigia octovalvis (Jacq.) Raven, 58~90g of ox, 180~320g of reed rhizome, 115~230g of honeysuckle, auxiliary material:Superfine silica gel powder, Microcrystalline cellulose and appropriate starch.
A kind of capsule medicine and preparation method for being used to treat acne rosacea, it is characterised in that each group of the medicine Divide and its mass parts are than as follows:
Cape jasmine 200g, radix scutellariae 95g, rust-coloured crotalaria herb with root 420g, peach kernel 118g, Radix Angelicae Sinensis 118g, Chinese trumpet creeper 60g, Ligusticum wallichii 80g, safflower 95g, Folium isatidis 118g, loguat leaf 80g, radix scrophulariae 115g, Ludwigia octovalvis (Jacq.) Raven 260g, ox 80g, reed rhizome 260g, honeysuckle 200g, auxiliary material:It is micro- Powder silica gel, microcrystalline cellulose and appropriate starch.
A kind of capsule medicine and preparation method for being used to treat acne rosacea, it is characterised in that methods described includes as follows Step is prepared:
A, after above-mentioned raw materials Chinese medicine being picked into impurity and dust, it is ground into according to mass parts than altogether(30~50 mesh)Graininess bag Decoct;
B, 1. the raw material Chinese medicine wrapped is put into cold boiling water and soaks 50min, then soaked medicine is put into marmite again, The cold boiling water for adding 7~8 times of raw material Chinese medicine weight carries out first time high heat decoction, when 18min is arrived in decoction, turns slow fire and boils 120min, leaching decoction;2. the cold boiling water for adding 6~7 times of raw material Chinese medicine weight in the dregs of a decoction again is fried by intense fire for the second time Boil, when 15min is arrived in decoction, turn slow fire and boil 110min, leaching decoction;3. decoction mixing twice is condensed into relative density is 1.08 clear cream, then dry, grind and sterilize after it is stand-by;
C, the method for 1. preparing Chinese medicine capsules according to tradition, after above-mentioned ground smalls sieving, appropriate micro mist is added Silica gel, microcrystalline cellulose and starch are well mixed, and are then prepared into capsule(Total length is 23.3mm after its capsule is sealed, medicine Powder capacity 0.4~0.5g/ grains), 2. then polish, sterilize, sealed packaging.
It is a kind of to be used to treat the capsule medicine and preparation method of acne rosacea, it is characterised in that the instructions of taking is:Will The capsule medicine prepared is twice a day to take, and once a dose sooner or later, dosage 3.5g(7)/ time, warm water delivery service. 15 days are a course for the treatment of, treat 2~3 courses for the treatment of, and symptom disappears, and disease obtains recovery from illness.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component:
Cape jasmine, nature and flavor:Hardship, tremble with fear, have heat-clearing, purging intense heat, cool blood the effect of, for treat pyreticosis restlessness of asrhenia type and insomnia, jaundice, gonorrhoea, Quench one's thirst, hot eyes, pharyngalgia, haematemesis, bleeding from five sense organs or subcutaneous tissue, bloody flux, hematuria, pathopyretic ulcer, sprain swelling and pain;
Radix scutellariae, nature and flavor:It is bitter, cold in nature, have clearing heat-fire, eliminating dampness removing toxic substances, hemostasis, it is antiabortive the effect of, for treating lung heat cough Cough, the headache of high fever apoplexy coma due to blocking of the respiratory system shies epilepsy, irascibility, red eye, swell pain, jaundice with damp-heat pathogen, rush down dysentery, heat gonorrhea, hematemesis blood, uterine bleeding, fetal movement with fever, carbuncle Swollen furunculosis;
Rust-coloured crotalaria herb with root, nature and flavor:It is bitter slightly sour, cold, there is the effect of gas of astringing the lung, tonifying spleen kidney, diuresis, malicious detumescence, for treating chronic cough The diseases such as phlegm blood, tinnitus, deafness, nocturnal emission, chronic nephritis, cystitis, kidney stone, tonsillitis, adenolymphitis, serious case of furuncle, malignant sore;
Peach kernel, nature and flavor:It is bitter sweet, flat, there is the effect of blood-breaking row stasis of blood, moisturize laxation, for treating Amenorrhea, Disorder lumps in the abdomen, pyreticosis stores blood, The dry constipation of wandering arthritis, malaria, traumatic injury, blood stasis and swelling pain, blood;
Radix Angelicae Sinensis, nature and flavor:It is sweet, pungent, slight bitter, warm-natured, there is the effect of benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation, for treating Irregular menstruation, Amenorrhea stomachache, Disorder lumps in the abdomen knot are poly-, uterine bleeding;Headache due to deficiency of blood, dizziness, Impotence numbness, intestines are dry and shit is difficult, weight after dysentery characterized by blood in the stool, ulcer sore Surreptitiously, the disease such as injury from falling down;
Chinese trumpet creeper, nature and flavor:Sour, cold nature, there is the effect of clearing heat and cooling blood, blood stasis-eliminating and stagnation-dissipating, dispelling wind and arresting itching, for treating stasis Amenorrhea, dysmenorrhoea, abdominal mass, metrorrhagia and metrostaxis, blood-head pruritus, sore scabies fall into rash, rosacea, cool blood, stagnation resolvation, wind-dispelling, for irregular menstruation, The disease such as Jing Bi wei lump in the abdomen, postpartum breast swollen, rubella is rubescent, pruitus, acne;
Ligusticum wallichii, nature and flavor:It is pungent, warm, there is the effect of blood-activating and qi-promoting, wind-expelling pain-stopping, for treating irregular menstruation, closed dysmenorrhea, disease Lump in the abdomen stomachache, chest side of body shouting pain, tumbling and swelling, headache, arthralgia pain due to rheumatism;
Safflower, nature and flavor:It is acrid flavour, warm-natured, there is the effect of promoting blood circulation can be through, stasis-dispelling and pain-killing, for treating Amenorrhea, dysmenorrhoea, the postpartum stasis of blood The diseases such as resistance stomachache, born of the same parents' numbness pained a lump in the abdomen causing distension and pain, traumatic injury, arthralgia, middle windage yaw are completed, macula;
Folium isatidis, nature and flavor:It is bitter, cold, there is the effect of clearing heat and detoxicating, blood cooling and ecchymoses removing, for treat pyreticosis hyperpyrexia polydipsia, coma, The diseases such as macula, haematemesis, bleeding from five sense organs or subcutaneous tissue, jaundice, rush down dysentery, erysipelas, larynx numbness, aphtha, mumps;
Loguat leaf, nature and flavor:Hardship, it is slightly cold, there is the effect of removing heat from the lung to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI, for treats cough with lung heat, circulation of vital energy in the wrong direction asthma Anxious, stomach energy is vomitted inverse, dysphoria and thirsty;
Radix scrophulariae, nature and flavor:Sweet, bitter, salty, cold nature, there is the effect of clearing heat and cooling blood, nourishing Yin and falling fire, detoxicating and resolving a mass, for treating Warm heat disease heat and ying blood, body heat, polydipsia, tongue are deep red, send out spot, hectic fever due to yin labor is coughed, dysphoria not puckery dim-sighted, the throat larynx of awake, Tianjin hinder constipation, mesh Swelling and pain, scrofula subcutaneous nodule, skin sore;
Ludwigia octovalvis (Jacq.) Raven, nature and flavor:It is bitter, micro-pungent, cold in nature, there is the effect of clearing heat and promoting diuresis, removing toxicity for detumescence, for treat cold, fever, Children's infantile malnutrition due to digestive disturbances or intestinalparasites heat, abscess of throat, aphthae, hypertension, oedema, damp-heat dysentery, leaching pain, gonorrhoea, with, acute mastitis, furuncle swelling toxin, Hemorrhoid, burn and scald, venomous snake bite;
Niu Zi, nature and flavor:It is pungent, bitter, cold, there is the effect of dispelling wind, promoting eruption, relieving sore-throat, detumescence, for treating anemopyretic cold, cough, rash Go out not smooth, abscess of throat, nettle rash, mumps, carbuncle sore tumefacting virus;
Reed rhizome, nature and flavor:It is sweet, cold, there is the effect of clearing heat and promoting fluid, relieving restlessness, preventing or arresting vomiting, diuresis, for treating pyreticosis polydipsia, stomach energy is vomitted Tell, cough with lung heat, lung carbuncle pyemesis, puckery pain of heat gonorrhea;
Honeysuckle, nature and flavor:Property it is sweet, cold, there is the effect of clearing heat and detoxicating, anti-inflammatory detumescence, for treating affection of exogenous wind-heat or warm disease hair Heat, heatstroke, toxic-heat and blood stasis, carbuncle swells furunculosis, larynx numbness, multi-infection disease.
Medicine of the present invention is the principle based on Chinese traditional treatment brandy nose, from the pathomechanism according to brandy nose and pharmacological action Think:With regard to brandy nose, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, has good treatment to above-mentioned disease Effect.
Embodiment
A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned brandy nose, the medicine prepared using the formula Thing good drug efficacy, it is quick, it is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the specific reality of the present invention The mode of applying is described in further detail:
Embodiment 1:
A kind of capsule medicine for being used to treat acne rosacea, it is characterised in that each component and its mass parts ratio of the medicine It is as follows:
Cape jasmine 200g, radix scutellariae 95g, rust-coloured crotalaria herb with root 420g, peach kernel 118g, Radix Angelicae Sinensis 118g, Chinese trumpet creeper 60g, Ligusticum wallichii 80g, safflower 95g, Folium isatidis 118g, loguat leaf 80g, radix scrophulariae 115g, Ludwigia octovalvis (Jacq.) Raven 260g, ox 80g, reed rhizome 260g, honeysuckle 200g, auxiliary material:It is micro- Powder silica gel, microcrystalline cellulose and appropriate starch.
Embodiment 2:
A kind of capsule medicine for being used to treat acne rosacea, it is characterised in that each component and its mass parts ratio of the medicine It is as follows:
Cape jasmine 220g, radix scutellariae 105g, rust-coloured crotalaria herb with root 480g, peach kernel 130g, Radix Angelicae Sinensis 130g, Chinese trumpet creeper 70g, Ligusticum wallichii 90g, safflower 105g, folium isatidis 130g, loguat leaf 90g, radix scrophulariae 130g, Ludwigia octovalvis (Jacq.) Raven 320g, ox 90g, reed rhizome 320g, honeysuckle 230g, it is auxiliary Material:Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
Embodiment 3:
A kind of capsule medicine for being used to treat acne rosacea, it is characterised in that each component and its mass parts ratio of the medicine It is as follows:
Cape jasmine 250g, radix scutellariae 120g, rust-coloured crotalaria herb with root 550g, peach kernel 160g, Radix Angelicae Sinensis 160g, 30~80g of Chinese trumpet creeper, Ligusticum wallichii 30~ 100g, 50~120g of safflower, 100~160g of folium isatidis, 60~100g of loguat leaf, 90~160g of radix scrophulariae, Ludwigia octovalvis (Jacq.) Raven 150~ 50~100g of 360g, ox, 150~360g of reed rhizome, 100~260g of honeysuckle, auxiliary material:Superfine silica gel powder, microcrystalline cellulose and shallow lake Appropriate powder.
Curative effect determinate standard:According to《Chinese medical disease Standardization of diagnosis and curative effect》
Its model case is as follows:
Through clinical conditions brandy nose patient totally 1480, the age is 850 of more than 32 years old, only 630 for 32 years old with Under.750 to be fully recovered in 1480 patients, effective 626, invalid 104.Total effective rate is up to 93%.

Claims (3)

1. a kind of capsule medicine for being used to treat acne rosacea, it is characterised in that each component and its mass parts of the medicine Than as follows:
100~250g of cape jasmine, 30~120g of radix scutellariae, 250~550g of rust-coloured crotalaria herb with root, 80~160g of peach kernel, 80~160g of Radix Angelicae Sinensis, reach the clouds Spend 30~80g, 30~100g of Ligusticum wallichii, 50~120g of safflower, 100~160g of folium isatidis, 60~100g of loguat leaf, radix scrophulariae 90~ 160g, 150~360g of Ludwigia octovalvis (Jacq.) Raven, 50~100g of ox, 150~360g of reed rhizome, 100~260g of honeysuckle, auxiliary material:Micro mist silicon Glue, microcrystalline cellulose and appropriate starch.
2. according to claim 1 be used to treat the capsule medicine of acne rosacea, it is characterised in that the medicine it is each Component and its mass parts are than as follows:
115~220g of cape jasmine, 38~105g of radix scutellariae, 280~480g of rust-coloured crotalaria herb with root, 90~130g of peach kernel, 90~130g of Radix Angelicae Sinensis, reach the clouds Spend 38~70g, 38~90g of Ligusticum wallichii, 58~105g of safflower, 115~130g of folium isatidis, 68~90g of loguat leaf, radix scrophulariae 100~ 130g, 180~320g of Ludwigia octovalvis (Jacq.) Raven, 58~90g of ox, 180~320g of reed rhizome, 115~230g of honeysuckle, auxiliary material:Superfine silica gel powder, Microcrystalline cellulose and appropriate starch.
3. the capsule medicine for being used to treat acne rosacea according to claim 1 to 2, it is characterised in that the medicine Each component and its mass parts are than as follows:
Cape jasmine 200g, radix scutellariae 95g, rust-coloured crotalaria herb with root 420g, peach kernel 118g, Radix Angelicae Sinensis 118g, Chinese trumpet creeper 60g, Ligusticum wallichii 80g, safflower 95g, Folium isatidis 118g, loguat leaf 80g, radix scrophulariae 115g, Ludwigia octovalvis (Jacq.) Raven 260g, ox 80g, reed rhizome 260g, honeysuckle 200g, auxiliary material:It is micro- Powder silica gel, microcrystalline cellulose and appropriate starch.
CN201710870605.XA 2017-09-23 2017-09-23 A kind of capsule medicine and preparation method for being used to treat acne rosacea Withdrawn CN107519409A (en)

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Application publication date: 20171229