CN107812049A - Pharmaceutical composition for treating icteric hepatitis and its production and use - Google Patents

Pharmaceutical composition for treating icteric hepatitis and its production and use Download PDF

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CN107812049A
CN107812049A CN201711165638.0A CN201711165638A CN107812049A CN 107812049 A CN107812049 A CN 107812049A CN 201711165638 A CN201711165638 A CN 201711165638A CN 107812049 A CN107812049 A CN 107812049A
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parts
pharmaceutical composition
icteric hepatitis
phoenix
renzicao
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姚元艳
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    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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Abstract

The invention provides a kind of pharmaceutical composition for being used to treat icteric hepatitis and its production and use, it is related to drug field.The pharmaceutical composition count in parts by weight including:4~8 parts of 5~10 parts of oriental wormwood, 2~6 parts of sweet wormwood, 6~10 parts of phoenix-tail fern, 4~8 parts of RENZICAO, 15~25 parts of cattle hide, 2~6 parts of kuh-seng, 4~8 parts of soulie barberry bark and Chinese Fevervine Herb.Its preparation method is included after said medicine is mixed, and is extracted using solvent extraction method.Pharmaceutical composition, by from clearing heat and promoting diuresis, normalizing gallbladder to cure jaundice, remove heat from the blood and induce diuresis drug combination in terms of these three, reduce the hot gas and general mood of patient's body, while invigorating the spleen, clearing lung-heat diuresis, there is preferable therapeutic effect to icteric hepatitis.

Description

Pharmaceutical composition for treating icteric hepatitis and its production and use
Technical field
The present invention relates to drug field, in particular to a kind of pharmaceutical composition for being used to treat icteric hepatitis and Preparation method and use.
Background technology
Icteric hepatitis disease is a kind of because hepatitis viruse invades liver, and the liver caused by continuous duplication in liver cell Inflammation, its based on whether there is jaundice performance and abnormal level of serum total bilirubin whether raise to define, corresponding is no Huang Subcutaneous ulcer type hepatitis.
After hepatitis viruse invades liver, under the immune response effect of body, liver cell is damaged together, makes liver cell water It is swollen, destroying makes liver organization that inflammatory occur invades profit, hyperemia, oedema, oozes out, a series of changes such as degeneration of liver cells and necrosis.Suffer from Have icteric hepatitis disease patient typically with it is weak, detest it is greasy, nauseous, with the symptom such as skin and mucous membrane xanthochromia.However, mesh Before also lack it is a kind of being capable of quick acting and the medicine that effectively effects a radical cure to the disease.
The content of the invention
The first object of the present invention is to provide a kind of pharmaceutical composition for being used to treat icteric hepatitis, by from heat-clearing Dampness removing, normalizing gallbladder to cure jaundice, remove heat from the blood and induce diuresis these three aspect drug combinations, reduces the hot gas and general mood of patient's body, while invigorating the spleen, clear Lung diuresis, there is preferable therapeutic effect to icteric hepatitis.
The second object of the present invention is to provide a kind of preparation method of aforementioned pharmaceutical compositions.
The third object of the present invention is in medicine or health products of the pharmaceutical composition in preparation treatment icteric hepatitis Purposes.
In order to realize the above-mentioned purpose of the present invention, spy uses following technical scheme:
It is a kind of to be used to treating the pharmaceutical composition of icteric hepatitis, pharmaceutical composition count in parts by weight including:
5~10 parts of oriental wormwood, 2~6 parts of sweet wormwood, 6~10 parts of phoenix-tail fern, 4~8 parts of RENZICAO, 15~25 parts of cattle hide, kuh-seng 4~8 parts of 2~6 parts, 4~8 parts of soulie barberry bark and Chinese Fevervine Herb.
A kind of preparation method of aforementioned pharmaceutical compositions, it includes:In parts by weight, by oriental wormwood, sweet wormwood, phoenix-tail fern, people After word grass, cattle hide, kuh-seng, soulie barberry bark, Chinese Fevervine Herb mixing, extracted using solvent extraction method.
A kind of purposes of pharmaceutical composition in the medicine or health products for preparing treatment icteric hepatitis.
Compared with prior art, beneficial effects of the present invention for example including:
The pharmaceutical composition by from clearing heat and promoting diuresis, normalizing gallbladder to cure jaundice, remove heat from the blood and induce diuresis drug combination in terms of these three, reduce and suffer from Hot gas and general mood in person's body, while invigorating the spleen, clearing lung-heat diuresis, to promote the recovery of patient's liver function;It is aided with analgesic drug product again, To mitigate the pain of patient.Be mainly used in treating abdominal distension stomachache, weakness of limbs, eyes skin nail turn to be yellow, apocleisis it is greasy, nauseous The various hepatitis symptoms such as vomiting, dry, face is bitter, tongue fur turns white, oedema is swum, urine pain, diarrhoea, urine jaundice.
Embodiment
Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will Understand, the following example is merely to illustrate the present invention, and is not construed as limiting the scope of the present invention.It is unreceipted specific in embodiment Condition person, the condition suggested according to normal condition or manufacturer are carried out.Agents useful for same or the unreceipted production firm person of instrument, it is The conventional products that can be obtained by commercially available purchase.
Present embodiment provides a kind of pharmaceutical composition for being used to treat icteric hepatitis, and the pharmaceutical composition is by weight Number meter includes:
5~10 parts of oriental wormwood, 2~6 parts of sweet wormwood, 6~10 parts of phoenix-tail fern, 4~8 parts of RENZICAO, 15~25 parts of cattle hide, kuh-seng 4~8 parts of 2~6 parts, 4~8 parts of soulie barberry bark and Chinese Fevervine Herb.
Or count in parts by weight, 6~9 parts of oriental wormwood, 3~5 parts of the sweet wormwood, 7~9 parts of the phoenix-tail fern, the herringbone 5~7 parts of grass, 18~23 parts of the cattle hide, 3~5 parts of the kuh-seng, 5~7 parts of the soulie barberry bark, described and Chinese Fevervine Herb 5~ 7 parts.
Or count in parts by weight, 7~8 parts of oriental wormwood, 4~5 parts of the sweet wormwood, 7~9 parts of the phoenix-tail fern, the herringbone 5~7 parts of grass, 19~21 parts of the cattle hide, 3~5 parts of the kuh-seng, 5~7 parts of the soulie barberry bark, described and Chinese Fevervine Herb 5~ 7 parts.
Or count in parts by weight, 8 parts of the oriental wormwood, 4 parts of the sweet wormwood, 8 parts of the phoenix-tail fern, the RENZICAO 6 Part, 20 parts of the cattle hide, 4 parts of the kuh-seng, 6 parts of the soulie barberry bark, 6 parts of the Chinese Fevervine Herb.
The pharmaceutical composition for icterepatitis, mainly from clearing heat and promoting diuresis, normalizing gallbladder to cure jaundice, remove heat from the blood and induce diuresis in terms of these three Drug combination, specifically:
Oriental wormwood, there is the effect of eliminating dampness and heat, normalizing gallbladder to cure jaundice.
Sweet wormwood, have clearind deficient heat, except hectic fever due to yin, solution hot summer weather, preventing malaria, removing jaundice the effect of.
Phoenix-tail fern, there is the effect of clearing heat and promoting diuresis, cooling blood and hemostasis, subdhing swelling and detoxicating.
RENZICAO, there is the effect of clearing heat and promoting diuresis, invigorating the spleen, clearing lung-heat diuresis.
Cattle hide, there is the effect of reducing fever and causing diuresis, clearing heat and eliminating phlegm, hemostasis antidiarrheal.
Kuh-seng, there is the effect of heat-clearing and damp-drying drug, desinsection diuresis.
Soulie barberry bark, it is little Nie sections plant, there is the effect of clearing heat and detoxicating, eliminating dampness.
Chinese Fevervine Herb, there is the effect of expelling wind and removing dampness, promoting digestion and removing indigestion, cough-relieving relieves pain.
The pharmaceutical composition by from clearing heat and promoting diuresis, normalizing gallbladder to cure jaundice, remove heat from the blood and induce diuresis drug combination in terms of these three, reduce and suffer from Hot gas and general mood in person's body, while invigorating the spleen, clearing lung-heat diuresis, to promote the recovery of patient's liver function;It is aided with analgesic drug product again, To mitigate the pain of patient.Be mainly used in treating abdominal distension stomachache, weakness of limbs, eyes skin nail turn to be yellow, apocleisis it is greasy, nauseous The various hepatitis symptoms such as vomiting, dry, face is bitter, tongue fur turns white, oedema is swum, urine pain, diarrhoea, urine jaundice.
Further, the pharmaceutical composition is counted also include in parts by weight:2~6 parts of yellow avens.With icterepatitis Patient adds often with the symptom of abdominal distension, therefore for the abdominal distension symptom of more preferable reduction of patient in the pharmaceutical composition Enter yellow avens.Yellow avens is the plant of rose family yellow avens category, all herbal medicine, there is wind-dispelling, dehumidifying, analgesic, antispasmodic work( Effect.
Further, the pharmaceutical composition is counted also include in parts by weight:4~8 parts of purple perilla, 4~8 parts of peppermint.Some trouble There is the tongue fur of the patient of icterepatitis partially white, illustrate that patient's body has general mood and cold air still on top layer, therefore, in the medicine group Purple perilla and peppermint this two tastes diaphoretic medicine are added in compound.Wherein, purple perilla, there is the effect of relieving exterior syndrome and dispelling cold, relieving QI stagnancy in the stomach;Peppermint, The effect of with dispelling wind and heat from the body, soothing the liver promoting the circulation of qi.
Further, the pharmaceutical composition is counted also include in parts by weight:4~8 parts of Japanese Premna Herb.It is some to suffer from icterepatitis Patient with the symptom of odynuria, therefore, Japanese Premna Herb is added in the pharmaceutical composition.Japanese Premna Herb, also known as ringdove leaf, it has clear The effect of thermal detoxification.
Further, the pharmaceutical composition is counted also include in parts by weight:4~8 parts of kalimeris grass roots.Wherein, kalimeris grass roots For the root of composite family kalimeris platymiscium kalimeris, alias:Loach string root.Some patients with icterepatitis with diarrhoea disease Shape, therefore, kalimeris grass roots is added in the pharmaceutical composition.Kalimeris grass roots, there is cooling blood and hemostasis, clearing heat and promoting diuresis, removing toxic substances to disappear for it The effect of swollen.
A kind of preparation method of the pharmaceutical composition, it includes:
In parts by weight, by the oriental wormwood, sweet wormwood, the phoenix-tail fern, the RENZICAO, the cattle hide, described After kuh-seng, the soulie barberry bark, Chinese Fevervine Herb mixing, extracted using solvent extraction method.
The solvent extraction method include decocting method, reflux extraction, ultrasonic vibration extraction method, microwave loss mechanisms, percolation and Any one in infusion process.It is more preferable, using ultrasonic vibration extraction method, specifically, by above-mentioned medicinal material mixture and water Mixing, in the case where power is 800~1200W, temperature is 25~45 DEG C, 0.5~1h of ultrasound, circulate 2~3 times.
Further, in addition to by using solvent extraction method extract obtained extract and pharmaceutically acceptable auxiliary material or Carrier mixes.
Herein, it is physiologically acceptable that term " pharmaceutically acceptable ", which refers to the compound when compound is to human administration, , and the allergic reactions such as gastrointestinal disturbance, dizziness or these similar anaphylactoid systemic anaphylaxis will not occur.
In the present invention, " pharmaceutically acceptable auxiliary material or carrier " includes but is not limited to:Adhesive (such as microcrystalline cellulose Element, alginates, gelatin and polyvinylpyrrolidone), filler (such as starch, sucrose, glucose and anhydrous lactic acid), disintegrant (such as cross-linked pvp, crosslinked carboxymethyl fecula sodium, Ac-Di-Sol and low-substituted hydroxypropyl cellulose), lubricant (magnesium stearate, aluminum stearate, talcum, polyethylene glycol, sodium benzoate), wetting agent (such as glycerine), surfactant (such as hexadecane Alcohol) and sorbefacient, flavouring, sweetener, diluent, coating agent etc..
In order that the pharmaceutical composition discharge active component, medicine of the invention rapidly, continuously and in a very long time Compositions can manufacture in production process according to those conventional methods in the art are disclosed in.The medicine of the present invention The method of administration of composition is oral, nasal inhalation or parenteral.The preparation of the pharmaceutical composition can be powder, particle, Tablet, emulsion, syrup, aerosol, soft capsule, hard shell capsules, sterile injectable preparation and sterilized powder etc..
A kind of purposes of pharmaceutical composition in the medicine or health products for preparing treatment icteric hepatitis.
The pharmaceutical composition, formula is reasonable, and cost is cheap, by from clearing heat and promoting diuresis, normalizing gallbladder to cure jaundice, remove heat from the blood and induce diuresis these three Aspect drug combination, the hot gas and general mood of patient's body, while invigorating the spleen, clearing lung-heat diuresis are reduced, to promote the extensive of patient's liver function It is multiple;It is aided with analgesic drug product again, to mitigate the pain of patient.For a variety of symptoms of icteric hepatitis, there is good improvement Therapeutic action, for example, improve abdominal distension stomachache, weakness of limbs, eyes skin nail turn to be yellow, apocleisis is greasy, nausea and vomiting, dry, mouth The hepatitis symptom such as bar hardship, tongue fur turns white, oedema is swum, urine pain, diarrhoea, urine jaundice, has treatment to imitate to icterepatitis Fruit is good, available for the medicine or health products for preparing treatment icteric hepatitis.
The feature and performance of the present invention are described in further detail with reference to embodiments:
Embodiment 1
The present embodiment provides a kind of pharmaceutical composition for being used to treat icteric hepatitis, and it includes:
5 parts of oriental wormwood, 6 parts of sweet wormwood, 6 parts of phoenix-tail fern, 8 parts of RENZICAO, 25 parts of cattle hide, 2 parts of kuh-seng, 8 parts of soulie barberry bark and 4 parts of Chinese Fevervine Herb.
The preparation method of the pharmaceutical composition includes:
After oriental wormwood, sweet wormwood, phoenix-tail fern, RENZICAO, cattle hide, kuh-seng, soulie barberry bark, Chinese Fevervine Herb are mixed, according to solid-liquid ratio 1:6 addition water are decocted, and moderate heat boils, then small fire boils 15min, are decocted twice, are merged decoction liquor, produce.
Embodiment 2
The present embodiment provides a kind of pharmaceutical composition for being used to treat icteric hepatitis, and it includes:
8 parts of oriental wormwood, 4 parts of sweet wormwood, 8 parts of phoenix-tail fern, 6 parts of RENZICAO, 20 parts of cattle hide, 4 parts of kuh-seng, 6 parts of soulie barberry bark and 6 parts of Chinese Fevervine Herb.
The preparation method of the pharmaceutical composition includes:
After oriental wormwood, sweet wormwood, phoenix-tail fern, RENZICAO, cattle hide, kuh-seng, soulie barberry bark, Chinese Fevervine Herb are mixed, according to solid-liquid ratio 1:6 mix with 60% ethanol solution, are extracted using ultrasonic vibration extraction method, extract 0.5h under 30 DEG C, 1000W, follow Ring 2 times, merge extract solution, after being concentrated under reduced pressure, produce.
Embodiment 3
The present embodiment provides a kind of pharmaceutical composition for being used to treat icteric hepatitis, and it includes:
10 parts of oriental wormwood, 2 parts of sweet wormwood, 10 parts of phoenix-tail fern, 4 parts of RENZICAO, 15 parts of cattle hide, 6 parts of kuh-seng, 4 parts of soulie barberry bark, with And 8 parts of Chinese Fevervine Herb.
The preparation method of the pharmaceutical composition includes:
After oriental wormwood, sweet wormwood, phoenix-tail fern, RENZICAO, cattle hide, kuh-seng, soulie barberry bark, Chinese Fevervine Herb are mixed, according to solid-liquid ratio 1:6 mix with 80% ethanol solution, are extracted using heating and refluxing extraction method, extract 2h, second of extraction 1h for the first time, Merge extract solution, after being concentrated under reduced pressure, produce.
Embodiment 4
The present embodiment provides a kind of pharmaceutical composition for being used to treat icteric hepatitis, and it includes:
8 parts of oriental wormwood, 4 parts of sweet wormwood, 8 parts of phoenix-tail fern, 6 parts of RENZICAO, 20 parts of cattle hide, 4 parts of kuh-seng, 6 parts of soulie barberry bark, chicken droppings 6 parts of rattan, 4 parts of yellow avens.
The preparation method of the pharmaceutical composition includes:
After oriental wormwood, sweet wormwood, phoenix-tail fern, RENZICAO, cattle hide, kuh-seng, soulie barberry bark, Chinese Fevervine Herb, yellow avens are mixed, according to Solid-liquid ratio 1:6 mix with 60% ethanol solution, are extracted using ultrasonic vibration extraction method, are extracted under 30 DEG C, 1000W 0.5h, circulate 2 times, merge extract solution, after being concentrated under reduced pressure, produce.
Embodiment 5
The present embodiment provides a kind of pharmaceutical composition for being used to treat icteric hepatitis, and it includes:
8 parts of oriental wormwood, 4 parts of sweet wormwood, 8 parts of phoenix-tail fern, 6 parts of RENZICAO, 20 parts of cattle hide, 4 parts of kuh-seng, 6 parts of soulie barberry bark, chicken droppings 6 parts of rattan, 6 parts of purple perilla, 6 parts of peppermint.
The preparation method of the pharmaceutical composition includes:
After oriental wormwood, sweet wormwood, phoenix-tail fern, RENZICAO, cattle hide, kuh-seng, soulie barberry bark, Chinese Fevervine Herb, purple perilla, peppermint are mixed, According to solid-liquid ratio 1:8 mix with 80% ethanol solution, are extracted using ultrasonic vibration extraction method, are carried under 35 DEG C, 900W 0.8h is taken, is circulated 2 times, merges extract solution, after being concentrated under reduced pressure, produces.
Embodiment 6
The present embodiment provides a kind of pharmaceutical composition for being used to treat icteric hepatitis, and it includes:
6 parts of oriental wormwood, 3 parts of sweet wormwood, 9 parts of phoenix-tail fern, 7 parts of RENZICAO, 18 parts of cattle hide, 3 parts of kuh-seng, 5 parts of soulie barberry bark, chicken droppings 7 parts of rattan, 4 parts of Japanese Premna Herb.
The preparation method of the pharmaceutical composition includes:
After oriental wormwood, sweet wormwood, phoenix-tail fern, RENZICAO, cattle hide, kuh-seng, soulie barberry bark, Chinese Fevervine Herb, Japanese Premna Herb are mixed, according to material Liquor ratio 1:8 are mixed with 75% ethanol solution, are extracted using ultrasonic vibration extraction method, and 1h is extracted under 25 DEG C, 1200W, Circulation 2 times, merge extract solution, after being concentrated under reduced pressure, produce.
Embodiment 7
The present embodiment provides a kind of pharmaceutical composition for being used to treat icteric hepatitis, and it includes:
9 parts of oriental wormwood, 5 parts of sweet wormwood, 7 parts of phoenix-tail fern, 5 parts of RENZICAO, 23 parts of cattle hide, 5 parts of kuh-seng, 7 parts of soulie barberry bark, chicken droppings 5 parts of rattan, 6 parts of yellow avens, 8 parts of kalimeris grass roots.
The preparation method of the pharmaceutical composition includes:
Oriental wormwood, sweet wormwood, phoenix-tail fern, RENZICAO, cattle hide, kuh-seng, soulie barberry bark, Chinese Fevervine Herb, yellow avens, kalimeris grass roots are mixed After conjunction, according to solid-liquid ratio 1:7 mix with 65% ethanol solution, are extracted using ultrasonic vibration extraction method, in 45 DEG C, 800W Lower extraction 0.5h, circulate 3 times, merge extract solution, after being concentrated under reduced pressure, produce.
Implement case:
Case one:
Wu, man, 41 years old, suffer within 1988 icterohepatitis disease, symptom:Abdominal distension, diarrhoea, the jaundice of skin eyes nail.
The pharmaceutical composition of the offer of embodiment 7 is provided, after taking three auxiliaries, symptom mitigation, fully recovered after first quarter moon.
Case two:
Slowly certain, man, 48 years old, suffers from hepatitis, symptom in 2015:Yellowing of the skin, apocleisis is greasy, and weakness of limbs, tongue fur has In vain one layer,
The pharmaceutical composition of the offer of embodiment 5 is taken, after taking two auxiliaries.Symptom mitigation, fully recovered after 10 days.
Case three:
Luo, female, 39 years old, in June, 2017 hepatitis, symptom:Eyes, skin nail jaundice, apocleisis is greasy, four limbs without Power, urine urine jaundice, urine pain a little is drawn,
The pharmaceutical composition of the offer of embodiment 6 is provided, after taking two auxiliaries, symptom mitigation, fully recovered after a week.
Although illustrate and describing the present invention with specific embodiment, but will be appreciated that without departing substantially from the present invention's Many other change and modification can be made in the case of spirit and scope.It is, therefore, intended that in the following claims Including belonging to all such changes and modifications in the scope of the invention.

Claims (10)

1. a kind of pharmaceutical composition for being used to treat icteric hepatitis, it is characterised in that described pharmaceutical composition is in parts by weight Meter includes:
5~10 parts of oriental wormwood, 2~6 parts of sweet wormwood, 6~10 parts of phoenix-tail fern, 4~8 parts of RENZICAO, 15~25 parts of cattle hide, kuh-seng 2~6 4~8 parts of part, 4~8 parts of soulie barberry bark and Chinese Fevervine Herb.
2. the pharmaceutical composition according to claim 1 for being used to treat icteric hepatitis, it is characterised in that in parts by weight Meter, 6~9 parts of the oriental wormwood, 3~5 parts of the sweet wormwood, 7~9 parts of the phoenix-tail fern, 5~7 parts of the RENZICAO, the cattle hide 18~23 parts, 3~5 parts of the kuh-seng, 5~7 parts of the soulie barberry bark, described and 5~7 parts of Chinese Fevervine Herb.
3. the pharmaceutical composition according to claim 1 for being used to treat icteric hepatitis, it is characterised in that in parts by weight Meter, 8 parts of the oriental wormwood, 4 parts of the sweet wormwood, 8 parts of the phoenix-tail fern, 6 parts of the RENZICAO, 20 parts of the cattle hide, the hardship 4 parts of ginseng, 6 parts of the soulie barberry bark, 6 parts of the Chinese Fevervine Herb.
4. the pharmaceutical composition according to claim 1 for being used to treat icteric hepatitis, it is characterised in that the medicine group Compound is counted in parts by weight also to be included:2~6 parts of yellow avens.
5. the pharmaceutical composition according to claim 1 for being used to treat icteric hepatitis, it is characterised in that the medicine group Compound is counted in parts by weight also to be included:4~8 parts of purple perilla, 4~8 parts of peppermint.
6. the pharmaceutical composition according to claim 1 for being used to treat icteric hepatitis, it is characterised in that the medicine group Compound is counted in parts by weight also to be included:4~8 parts of Japanese Premna Herb.
7. the pharmaceutical composition according to claim 1 for being used to treat icteric hepatitis, it is characterised in that the medicine group Compound is counted in parts by weight also to be included:4~8 parts of kalimeris grass roots.
8. the preparation method of a kind of pharmaceutical composition as described in any one of claim 1~7, it is characterised in that it includes:Press Parts by weight, by the oriental wormwood, the sweet wormwood, the phoenix-tail fern, the RENZICAO, the cattle hide, the kuh-seng, the thorn After the coptis, Chinese Fevervine Herb mixing, extracted using solvent extraction method.
9. the preparation method of pharmaceutical composition according to claim 8, it is characterised in that the solvent extraction method includes decocting Any one in cooking method, reflux extraction, ultrasonic vibration extraction method, microwave loss mechanisms, percolation and infusion process.
10. a kind of pharmaceutical composition as described in any one of claim 1~7 is preparing the medicine for the treatment of icteric hepatitis or guarantor Purposes in strong product.
CN201711165638.0A 2017-11-21 2017-11-21 Pharmaceutical composition for treating icteric hepatitis and its production and use Pending CN107812049A (en)

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CN201711165638.0A CN107812049A (en) 2017-11-21 2017-11-21 Pharmaceutical composition for treating icteric hepatitis and its production and use

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1994378A (en) * 2006-12-27 2007-07-11 常熟雷允上制药有限公司 Compound formulation for treating icteric viral hepatitis and method for preparing same
CN101744954A (en) * 2009-12-29 2010-06-23 谭友民 Medicine for internally treating icteric hepatitis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1994378A (en) * 2006-12-27 2007-07-11 常熟雷允上制药有限公司 Compound formulation for treating icteric viral hepatitis and method for preparing same
CN101744954A (en) * 2009-12-29 2010-06-23 谭友民 Medicine for internally treating icteric hepatitis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
马敬民等: "苦黄注射液治疗急性黄疸型肝炎疗效观察", 《吉林中医药》 *

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