CN107789575A - A kind of traditional Chinese herbal decoction for being used to treat liver and spleen Qi-stagnation type narcolepsy - Google Patents

A kind of traditional Chinese herbal decoction for being used to treat liver and spleen Qi-stagnation type narcolepsy Download PDF

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CN107789575A
CN107789575A CN201610764877.7A CN201610764877A CN107789575A CN 107789575 A CN107789575 A CN 107789575A CN 201610764877 A CN201610764877 A CN 201610764877A CN 107789575 A CN107789575 A CN 107789575A
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parts
spleen
grams
traditional chinese
liver
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秦月霞
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Abstract

The invention discloses a kind of traditional Chinese herbal decoction for being used to treat liver and spleen Qi-stagnation type narcolepsy, it is prepared by the Chinese medicine of following weight proportion：9 parts of peony seed oil, 5 parts of cassia siamea leaf, 6 parts of alstonia-leaf, 7 parts of patrinia heterophylla, 8 parts of wild persimmon, 14 parts of cortex albiziae, 13 parts of Shi Sheng pivots flower bud, 12 parts of root tuber of aromatic turmeric, 10 parts of grass-leaved sweetflag, 11 parts of dried orange peel, 7 parts of rattan of centering, 6 parts of tea of the same trade or business, 5 parts of gomuti fibre, 4 parts of root tuber of aromatic turmeric, 5 parts of peppermint, 6 parts of the bighead atractylodes rhizome, 8 parts of Dendrobium aphyllum (Roxb.) C. E. Fisch., 7 parts of pistachio, 4 parts of Herba Saxifragae umbellalatae, 5 parts of rattletop, 6 parts of radix bupleuri, 7 parts of wild cumin.Clinical experiments have proved that reasonable compatibility of the present invention by Chinese medicine, helps to treat liver and spleen Qi-stagnation type narcolepsy, and it can effectively reduce complication and prevent from recurring, reach integrally-regulated and long-term effect good effects.

Description

A kind of traditional Chinese herbal decoction for being used to treat liver and spleen Qi-stagnation type narcolepsy
Technical field
The present invention relates to a kind of traditional Chinese herbal decoction, and in particular to a kind of Chinese medicine for being used to treat liver and spleen Qi-stagnation type narcolepsy Decoction.
Background technology
Narcolepsy is a kind of unclear syndrome of cause of disease, is characterized in being inclined to the sleep of exception, including daytime Hyper somnolence, nighttime sleep uneasiness and pathologic REM sleep.The not clear sleep-disorder of this reason, is mainly shown as long-term Watchful degree decline and paroxysmal irresistible sleep.Liver and spleen Qi-stagnation type narcolepsy, which is examined, sees chest gastral cavity turgor, very then aches Bitterly, vexed unclear, an irritability agitation, often sigh certainly, tongue nature is light, and tongue is thin white.Common tcm prescription only relies on several taste medicines and is difficult to Look after comprehensively, multi-medicament must suitably be coordinated, improve curative effect or reduce adverse reaction, to adapt to the treatment of the complicated state of an illness.Mirror Sufficiently complex, the pharmacokinetics of various medicines in vivo in the various active composition interaction in vivo of various Chinese medicines And the change of pharmacodynamics etc. can produce various influences to the interaction between medicine, during drug combination, both there may be The drug effect of Synergistic, it is also possible to antagonism is produced, and then causes drug therapy declines or Endodontic failure, some medicines Combination can also cause drug toxicity to strengthen, and cause adverse reaction；Even if drug combination causes effect to strengthen, but works as therapeutic action The ability that body is resistant to can be exceeded during degree enhancing, can also cause adverse reaction, or even endanger patient.Study toward plan certainly part Chinese medicinal formulae is to treat liver and spleen Qi-stagnation type narcolepsy, wherein most easily problem appear to is that the compatibility of medicines in a prescription is unreasonable, usually It is only to cure mainly to go to copy mechanically and apply indiscriminately traditional Chinese medical theory, prescription with some pharmacodynamic indexs from the discrete function of some singles or compound medicine Flavour of a drug are arbitrarily added and subtracted, and are caused prescription unreasonable, are contradicted with traditional Chinese medical theory.
The content of the invention
The present invention is intended to provide a kind of traditional Chinese herbal decoction for being used to treat liver and spleen Qi-stagnation type narcolepsy, passes through Chinese medicine Reasonable compatibility, help to treat liver and spleen Qi-stagnation type narcolepsy, and can effectively reduce complication and prevent from recurring, reach overall Regulation and the good effects of long-term effect.
In order to achieve the above object, the present invention uses following technical scheme：
A kind of traditional Chinese herbal decoction for being used to treat liver and spleen Qi-stagnation type narcolepsy, by the Chinese medicine preparation of following weight proportion Into：9 parts of peony seed oil, 5 parts of cassia siamea leaf, 6 parts of alstonia-leaf, 7 parts of patrinia heterophylla, 8 parts of wild persimmon, 14 parts of cortex albiziae, Shi Sheng pivot flower buds 13 parts, 12 parts of root tuber of aromatic turmeric, 10 parts of grass-leaved sweetflag, 11 parts of dried orange peel, centering 7 parts of rattan, 6 parts of tea of the same trade or business, 5 parts of gomuti fibre, 4 parts of root tuber of aromatic turmeric, peppermint 5 Part, 6 parts of the bighead atractylodes rhizome, 8 parts of Dendrobium aphyllum (Roxb.) C. E. Fisch., 7 parts of pistachio, 4 parts of Herba Saxifragae umbellalatae, 5 parts of rattletop, 6 parts of radix bupleuri, 7 parts of wild cumin.
Preparation method is：By the above-mentioned pulverizing medicinal materials in addition to peony seed oil into coarse powder；Decoct twice, decoct add for the first time 8 times of amounts of water, soak 2h, decoct 3h, filtration；6 times of amounts of second of decoction plus water, decoct 2h, filtration；Merge twice decocting liquid again with Dispensed after peony seed oil is well mixed.
The pharmacology analysis of each Chinese medicinal ingredients of the present invention is as follows：
Shi Sheng pivot flower buds【Source】For the herb of gentianaceae plant Shi Sheng pivot flower buds.【Nature and flavor】Hardship, tremble with fear.【Effect】Clearing liver gallbladder-heat, Sore heat, epidemic disease heat.Cure mainly fever, flu, baby diarrhea, sore caused by jaundice, liver and bladder disease.【Other】Bacteriostasis, resist Diarrhoea acts on.
Peony seed oil【Source】Peony seeds obtain the translucent fluid of crocus after squeezing, decolorization.Containing it is much more a large amount of not Saturated fatty acid, wherein mono- linolenic contents of a are especially prominent, at the same in peony seed oil also containing vitamin E, plant+c alcohol, A variety of nutritional ingredients beneficial to human body such as angle soft-shelled turtle alkene, trace element, in anti-oxidant, liver protection, reducing blood lipid, hypoglycemic, sun-proof etc. Aspect has the function that protrusion.
Cassia siamea leaf【Source】The drying leaflet of leguminosae cassia plant cassia siamea.【Nature and flavor】It is bitter, cold in nature, enter water, wind Tower.【Major function】Dispelling wind and eliminating dampness, swelling and pain relieving, desinsection are antipruritic.
Alstonia-leaf【Source】The drying leaf of Apocynaceae Alstonia plant common alstonia.【Nature and flavor】Bitter, micro-puckery, It is cold.【Major function】It is Qinghuo Jiedu, swelling and pain relieving, relieving cough and reducing sputum.
Patrinia heterophylla【Source】Valerianaceae Patrinia scaniosaefolia platymiscium patrinia heterophylla and patrinia scabra Bunge（Mountain Patrinia scaniosaefolia）, entered with root or herb Medicine.【Nature and flavor】It is bitter, slightly sour, puckery, it is cool.【Major function】Heat-clearing and damp-drying drug, hemostasis, stop-band, preventing malaria.For uterus erosion, early stage palace Neck cancer, leukorrhea, uterine bleeding, malaria.
Wild persimmon【Source】For root, branch and the leaf of Ebenaceae plant open country persimmon.【Nature and flavor】Bitter, puckery, gas is fragrant.It is cold in nature.【Function master Control】Four towers are nursed one's health, mend native stomach invigorating, Qinghuo Jiedu.Weak, do not feel like eating is cured mainly, weak and sickly, drought declines, jaundice, scald.
Centering rattan【Source】For the rattan of Icacinaceae plant centering rattan.【Nature and flavor】It is sweet, it is cool in nature.Bury, fire, wind tower. 【Major function】Relieve inflammation or internal heat and calm the nerves, normalizing gallbladder to cure jaundice, promoting blood circulation and stopping pain of ventilating.Cure mainly nervous palpitaition, the puckery pain of urine heat, jaundice, bruise Damage, fracture, rheumatic fever bi Zheng, limbs joint red and swollen heat pain, joint stuffiness.
Tea of the same trade or business【Source】The complete stool of the sharp sharp acute turpinia leaf of Staphyleaceae plant.【Nature and flavor】Bitter, it is cold in nature.【Effect】It is living Blood and dissolving stasis, swelling and pain relieving.Control hepatitis, hepatosplenomegaly, traumatic injury, fracture, venomous snake bite.
Gomuti fibre【Source】For the root of Zong Tong sections plant gomuti fibre.【Nature and flavor】It is the micro- sweet tea of taste, puckery.Gas is fragrant.It is mild-natured.【Major function】Adjust Mend four towers, lactagogue, Qinghuo Jiedu, normalizing gallbladder to cure jaundice.Waist and knee crymodynia is cured mainly, the whole body is weak, and sexual desire is cold, impotence, seminal emission, premature ejaculation, Lack of lactation after delivery, hypogalactia, jaundice.
Root tuber of aromatic turmeric【Source】This product is the dried root of zingiberaceous plant RADIX CURCUMAE, turmeric, Guangxi zedoary or zedoary.【Nature and flavor】 It is pungent, bitter, tremble with fear.【Channel tropism】Return liver, the heart, lung channel.【Major function】Regulating qi to disperse stagnation, heart fire-clearing upset-relieving, normalizing gallbladder to cure jaundice.For Amenorrhea pain Through chest and abdomen swelling and pain, shouting pain, pyreticosis coma, epilepsy goes mad, jaundice.
Peppermint【Source】The dry aerial parts of Labiatae mint peppermint.【Nature and flavor】It is pungent, it is cool.【Channel tropism】Return lung, Liver Channel.【Major function】Dispelling wind-heat.Refresh oneself, promoting eruption.For anemopyretic cold, wind-warm syndrome is from the beginning of, headache, hot eyes, larynx numbness, mouth Sore, rubella, measles, Breast bilges frowsty.
The bighead atractylodes rhizome【Source】This product is the dry rhizome of the feverfew bighead atractylodes rhizome.【Nature and flavor】It is bitter, sweet, temperature.【Channel tropism】Returns spleen, Stomach.【Major function】Strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis are antiabortive.For spleen eating less, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, water It is swollen, spontaneous perspiration, fetal irritability.Rhizoma Atractylodis Macrocephalae invigorating the spleen, and stomach, it is antiabortive.For spleen eating less, diarrhea loose stool, fetal irritability.
Dendrobium aphyllum (Roxb.) C. E. Fisch.【Source】For the false stem of orchid family bar thing Dendrobium aphyllum (Roxb.) C. E. Fisch..【Nature and flavor】Mildly bitter flavor, it is cool in nature.Enter water tower.【Effect Cure mainly】Qinghuo Jiedu, swelling and pain relieving, moisturizing are quenched the thirst, tranquilizing mind.Scald is cured mainly, is coughed, mouth parched and tongue scorched, abscess of throat, Scorching hot pain in stomach, dry mouth with bitter taste, the puckery pain of urine heat, it is vexed that ambition is swollen, insomnia.
Pistachio【Source】The fruits and seedses of Anacardiaceae plant pistachio.【Nature and flavor】It is damp and hot.【Major function】Tool Liver resistance is opened, nausea is eliminated, nourishing stomach institute, strengthens digestion, regulation stool, removing toxic substances, which is cured, to be created, and strengthens sexual desire, the work of warm lung cough-relieving With.Curing mainly liver has retardance, and nausea and vomiting, stomach institute is weak, product dyspepsia, overrich or excessively dilute of defecating, insect-bite, hyposexuality, Lymphatic temperament is coughed.
Herba Saxifragae umbellalatae【Source】The herb of castor tooth kiss-me.【Nature and flavor】Hardship, tremble with fear.Enter bladder, liver, courage three to pass through.【Effect master Control】Wind and heat dispersing, removing dampness through diuresis and removing jaundice.With control anemopyretic cold, headache nasal obstruction, dry throat, moss thin yellow superficial and rapid pulse person.With controlling damp and hot heap soil or fertilizer over and around the roots Stagnant liver and gall, compel bile is excessive, whole body know yellow, mesh Huang urinate it is yellow, receive and subtract rotten, the tired body of body and sink.
Rattletop【Source】The dry rhizome of ranunculaceae plant C.heracleifolia.【Nature and flavor】Pungent, micro-sweet, is slightly cold.【Channel tropism】Return Lung, spleen, stomach, large intestine channel.【Major function】Promoting eruption is delivered, it is clearing heat and detoxicating, rise and lift yang-energy.
Radix bupleuri【Source】The dry root of umbelliferae bupleurum or radix bupleuri scorzoneraefolii.【Major function】It is soothing the liver in inducing diaphoresis, rise Sun.For cold, fever, fevers and chills alternate, distending pain in the chest and hypochondrium, irregular menstruation, sub-official prolapses, prolapse of the anus.
Wild cumin【Source】For the seed of umbrella section plant open country cumin.【Nature and flavor】Three-level is xeothermic, acrid flavour.【Major function】It is raw dry Heat, strengthening tendons are good for flesh, and except the insane hysteria that disappears, cold-dispelling pain-relieving, warm lung cough-relieving is eliminating dampness and eliminating phlegm, diuresis and stone expeling, dispelling wind and arresting itching, stasis-resolving spot-removing. Humid or lymphatic temperament disease are cured mainly, is such as paralysed, disease of flaccid muscles, epilepsy, hysteria, marrow arthralgia, size arthralgia, ischium Neuralgia, cold cough, moist abundant expectoration, kidney stone, favus of the scalp, pruitus, various spot warts etc..
The present invention compared with prior art, has the advantages that：
1st, the selected medicament composing prescription of the present invention, its drug component are complemented each other using, have and act synergistically through dialectical compatibility, Treatment to liver and spleen Qi-stagnation type narcolepsy reaches treating a disease by looking into both its root cause and symptoms.Prescription is particular about monarch, four natures and five flavors of drug ascending-aescending-floating-sinking, closes Joyous skin, Shi Sheng pivots flower bud, root tuber of aromatic turmeric, grass-leaved sweetflag, dried orange peel etc. are altogether monarch drug in a prescription, are played a leading role in compound, by acting on main target Put to treat disease；Gomuti fibre, pistachio, wild persimmon, radix bupleuri, wild cumin etc. are ministerial drug, by acting on and monarch drug in a prescription identical target Put to strengthen the pharmacological action of monarch drug in a prescription, so as to reduce dosage needed for monarch drug in a prescription；Remaining is assistant, makes herbal medicine, to improve the life of monarch, ministerial drug Thing availability, coordinate the activity of their each compositions.Fang Zhong：Dried orange peel delays invigorating the spleen with root tuber of aromatic turmeric, grass-leaved sweetflag phase 5, dried orange peel, and root tuber of aromatic turmeric enters The heart, calamus is with, and three is used in combination, both waking up the patient from unconsciousness by clearing away heart fire, and invigorating spleen；Gomuti fibre is mild-natured, and pistachio is damp and hot, and wild persimmon is cold in nature, and three Person's Synergistic, then with the supporing yang qi-restoratives of a little radix bupleuri, the work(for the strong qi-restoratives that doubles；It is subject to the happy will of cortex albiziae, Shi Sheng pivots again Flower bud solution is strongly fragrant, wild cumin resolving sputum, all medicines it is all and, make eventually it is clear it is positive must rise, turbid yin must drop, phlegm wet must disappear, plot must relax, reduce drowsiness. In addition, caused synergy can produce the special work(for improving human immunologic function between peony seed oil, pistachio, alstonia-leaf Effect, can effectively adjust each function of body, improve the ability that body resists external toxin puzzlement, prevent complication generation and Prevent disease from recurring.Wet raw pivot flower bud, centering rattan share, the work(of the clear-headed brain of times lift-rising.
2nd, the present invention is directed to liver and spleen Qi-stagnation type narcolepsy pathogenesis, is controlled from Mutiple Targets, too many levels, multipath expansion Treat, in clinical practice with it is rapid-action, curative for effect, patient compliance is good, safe without toxic side effect, patient can be significantly improved Autoimmunity, treating both principal and secondary aspect of disease prevents from recurring, thus has wide potential applicability in clinical practice.
Embodiment
In order to more fully understand and implement the present invention, the present invention is further illustrated with reference to specific embodiment.
Embodiment 1
Weigh：It is 9 grams of peony seed oil, 5 grams of cassia siamea leaf, 6 grams of alstonia-leaf, 7 grams of patrinia heterophylla, 8 grams of wild persimmon, 14 grams of cortex albiziae, wet 13 grams of Sheng pivots flower bud, 12 grams of root tuber of aromatic turmeric, 10 grams of grass-leaved sweetflag, 11 grams of dried orange peel, centering 7 grams of rattan, 6 grams of tea of the same trade or business, 5 grams of gomuti fibre, 4 grams of root tuber of aromatic turmeric, 5 grams of peppermint, 6 grams of the bighead atractylodes rhizome, 8 grams of Dendrobium aphyllum (Roxb.) C. E. Fisch., 7 grams of pistachio, 4 grams of Herba Saxifragae umbellalatae, 5 grams of rattletop, 6 grams of radix bupleuri, wild cumin 7 Gram.
Preparation method is：By the above-mentioned pulverizing medicinal materials in addition to peony seed oil into coarse powder；Decoct twice, decoct add for the first time 8 times of amounts of water, soak 2h, decoct 3h, filtration；6 times of amounts of second of decoction plus water, decoct 2h, filtration；Merge twice decocting liquid again with Dispensed after peony seed oil is well mixed.
Usage and dosage：Orally, 2 times a day, each 1 time of morning and evening, each 100ml；30 days are 1 course for the treatment of, continuously take 2 treatments Journey.
Clinical data：
1st, case selection：
68 clinical observations of liver and spleen Qi-stagnation type narcolept in our hospital's diagnosis and treatment are selected, clinical symptoms meet liver and spleen gas Stagnant type narcolepsy diagnosis and treatment standard.Patient is randomly divided into two groups for the treatment of group and control group, treatment group 38, control group 30. The course of disease, the degrees of symptoms of two groups of cases for the treatment of group and control group are basically identical, no significant difference, have comparativity.
2nd, medicament selection：
The traditional Chinese herbal decoction obtained by the embodiment of the present invention 1 is taken by treatment group, orally, 2 times a day, each 1 time sooner or later, each 100ml； 30 days are 1 course for the treatment of.
Control group uses conventional western medicine complex treatment, the same treatment group of the course for the treatment of.
2 courses for the treatment of are treated in continuous smelting, contrast two groups of curative effects.
3rd, efficacy determination：
（1）Cure：Symptom disappears, and how subnormal laboratory examination is.
（2）Take a turn for the better：Cardinal symptom and laboratory examination have improvement.
（3）It is not cured：Symptom and laboratory examination are unchanged.
4th, result：
From in the treatment group of the traditional Chinese herbal decoction of the embodiment of the present invention 1,29 are cured, is taken a turn for the better 8, not more 1, cure rate 76.3%, Total effective rate 97.3%.Follow-up 24 months is tracked to curing patient, without 1 recurrence.
It is basic in control group to cure 12, take a turn for the better 11, not more 7, cure rate 40%, total effective rate 76.6%.To curing Patient tracks follow-up 24 months, 4 recurrences.
Result above shows, the cure rate and total effective rate for the treatment of group are apparently higher than control group.
Embodiment 2
Weigh：6 grams of alstonia-leaf, 6 grams of patrinia heterophylla, 5 grams of wild persimmon, centering 10 grams of rattan, 6 grams of tea of the same trade or business, 8 grams of gomuti fibre, 4 grams of root tuber of aromatic turmeric, 4 grams of peppermint, 6 grams of the bighead atractylodes rhizome, 8 grams of Dendrobium aphyllum (Roxb.) C. E. Fisch., 6 grams of pistachio, 4 grams of Herba Saxifragae umbellalatae, 4 grams of rattletop, 5 grams of radix bupleuri, wild cumin 10 grams.Preparation method is the same as embodiment 1.
From in 10 liver and spleen Qi-stagnation type narcolepts of traditional Chinese herbal decoction made of the embodiment of the present invention 2,8 are cured Example, effective 2.Cure rate 80%, total effective rate 100%.Follow-up 24 months is tracked to curing patient, without 1 recurrence.
Embodiment 3
Weigh：6 grams of alstonia-leaf, 6 grams of patrinia heterophylla, 5 grams of wild persimmon, centering 10 grams of rattan, 6 grams of tea of the same trade or business, 8 grams of gomuti fibre, 4 grams of root tuber of aromatic turmeric, 4 grams of peppermint, 6 grams of the bighead atractylodes rhizome, 8 grams of Dendrobium aphyllum (Roxb.) C. E. Fisch., 6 grams of pistachio, 4 grams of Herba Saxifragae umbellalatae, 4 grams of rattletop, 5 grams of radix bupleuri, wild cumin 10 grams.Preparation method is the same as embodiment 1.
From in 12 liver and spleen Qi-stagnation type narcolepts of traditional Chinese herbal decoction made of the embodiment of the present invention 3, cure 11, effective 1.Cure rate 91.6%, total effective rate 100%.Follow-up 24 months is tracked to taking a turn for the better and curing patient substantially, without 1 Example recurrence.
Obviously, the above embodiment of the present invention is only intended to clearly illustrate example of the present invention, and is not pair The restriction of embodiments of the present invention, such as the present invention also can use common technology that other oral agents are made in addition to decoction agent is made Type.Related Chinese medicine and its pharmacology can be obtained by existing open source literature and network, can also be with the medicinal material of close effect instead of It is alternative.For those of ordinary skill in the field, other multi-forms can also be made on the basis of the above description Change or variation.Here all embodiments can not be exhaustive.Every technical scheme that belongs to is extended Row of the obvious changes or variations gone out still in protection scope of the present invention.

Claims (3)

1. a kind of traditional Chinese herbal decoction for being used to treat liver and spleen Qi-stagnation type narcolepsy, it is characterised in that by following weight proportion Chinese medicine is prepared：9 parts of peony seed oil, 5 parts of cassia siamea leaf, 6 parts of alstonia-leaf, 7 parts of patrinia heterophylla, 8 parts of wild persimmon, cortex albiziae 14 Part, 13 parts of Shi Sheng pivots flower bud, 12 parts of root tuber of aromatic turmeric, 10 parts of grass-leaved sweetflag, 11 parts of dried orange peel, 7 parts of rattan of centering, 6 parts of tea of the same trade or business, 5 parts of gomuti fibre, root tuber of aromatic turmeric 4 parts, it is 5 parts of peppermint, 6 parts of the bighead atractylodes rhizome, 8 parts of Dendrobium aphyllum (Roxb.) C. E. Fisch., 7 parts of pistachio, 4 parts of Herba Saxifragae umbellalatae, 5 parts of rattletop, 6 parts of radix bupleuri, wild 7 parts of cumin.
A kind of 2. preparation side for being used to treat the traditional Chinese herbal decoction of liver and spleen Qi-stagnation type narcolepsy according to claim 1 Method, it is characterised in that by the above-mentioned pulverizing medicinal materials in addition to peony seed oil into coarse powder；Decoct twice, decoct add 8 times of water for the first time Amount, 2h is soaked, decoct 3h, filtration；6 times of amounts of second of decoction plus water, decoct 2h, filtration；Merge twice decocting liquid again with peony seeds Dispensed after oil is well mixed.
3. traditional Chinese herbal decoction according to claim 1 is in treatment or prevention liver and spleen Qi-stagnation type narcolepsy medicine is prepared Purposes.
CN201610764877.7A 2016-08-31 2016-08-31 A kind of traditional Chinese herbal decoction for being used to treat liver and spleen Qi-stagnation type narcolepsy Pending CN107789575A (en)

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Application publication date: 20180313