CN107789535A - A kind of preparation method for the Chinese medicine composition and its preparation for treating oral peculiar smell - Google Patents
A kind of preparation method for the Chinese medicine composition and its preparation for treating oral peculiar smell Download PDFInfo
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- CN107789535A CN107789535A CN201711431429.6A CN201711431429A CN107789535A CN 107789535 A CN107789535 A CN 107789535A CN 201711431429 A CN201711431429 A CN 201711431429A CN 107789535 A CN107789535 A CN 107789535A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- A61K35/413—Gall bladder; Bile
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/8969—Polygonatum (Solomon's seal)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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Abstract
A kind of Chinese medicine preparation for treating oral peculiar smell, it is made up of 50 400 parts of strangle careless, 50 250 parts of the root bark of white mulberry, 10 20 parts of pig's bile, 50 400 parts of Herba portulacae, 30 75 parts of sealwort, 10 50 parts of reed rhizome, 20 60 parts of the bletilla striata.The Chinese medicine preparation is:Capsule, gargle, granule, tablet, pill or oral solutions.Present invention treatment halitosis, sticky, the hot sense of tongue in mouth, bitter taste, mouth sweet tea, mouth is light, mouth is sour, tongue thick,yellow and greasy fur, fissured tongue, canker sore, evident in efficacy.
Description
Technical field
The present invention relates to a kind of preparation method for the Chinese medicine composition and its preparation for treating oral peculiar smell, belongs to traditional Chinese medicine neck
Domain.
Background technology
Oral peculiar smell includes:Sticky in halitosis, mouth, the hot sense of tongue, bitter taste, mouth sweet tea, mouth is light, mouth is sour, wherein, be much by
In caused by oral cavity partial illness, the traditional Chinese medical science thinks more category liver and gall heat symptom-complexs, stomach heat symptom-complex, damp heat in the spleen and the stomach strongly fragrant resistance, accumulate in liver and spleen convulsive seizure due to phlegm-fire,
The deficiency of the kidney yin, irascibility is partially prosperous, caused by stomach energy!Wherein, halitosis is also often some serious systemic disease oral appearances, is had
Organic illness also results in ozostomia.The traditional Chinese medical science thinks that the generation of halitosis comes from the various acute and chronic diseases of human body, such as Qing Dynasty
《The quiet candle of miscellaneous diseases source stream》Middle theory:" fire of deficiency type is hot and suffocating, accumulates the then halitosis, or rich people also halitosis of working with one's mind between chest stomach, or lung for fire
Bright halitosis, " by the dialectical discussion of traditional Chinese medical science institute, i.e. chest and abdomen are not smooth, adverse flow of turbid QI, stomach-Yin consumption wound, and raw in abnormal heat, stomach-Yin is damaged, body fluid
Deficiency, steam in the fire of deficiency type;Lung yin is impaired then to be rushed in the circulation of vital energy in the wrong direction;The impaired then hot and suffocating interior knot of the fire of deficiency type of vital essence blood, Yin and fluid deficiency stomach and intestine liver and gall are empty
The hot and suffocating upper steaming of fire, liver-fire invading the stomach, scorching in internal heat, the insufficiency of the spleen stagnation of the circulation of vital energy, fever and chills are mutually tied, disorder in ascending and descending institute and cause halitosis, this disease is in China
It is very common, have a strong impact on the communication and life of people.Therefore need to take effectively preventing measure to be intervened.Using the present invention
Treat halitosis, sticky, the hot sense of tongue in mouth, bitter taste, mouth sweet tea, mouth is light, mouth is sour, tongue thick,yellow and greasy fur, fissured tongue, canker sore,
It is evident in efficacy!
The content of the invention
It is an object of the invention to provide a kind of therapeutic effect it is good, have no toxic side effect, treatment oral peculiar smell curative for effect and
The preparation method of its preparation, with overcome the deficiencies in the prior art.
The technical scheme that the present invention solves above-mentioned technical problem is as follows:
A kind of Chinese medicine preparation for treating oral peculiar smell, is made up of the raw material of following parts by weight:
By strangle careless 50-400 parts, root bark of white mulberry 50-250 parts, pig's bile 10-20 parts, Herba portulacae 50-400 parts, sealwort 30-75 parts, reed
Root 10-50 parts, bletilla striata 20-60 parts.
As the further preferred of above-mentioned technical proposal, the composite preparation is made up of the raw material of following parts by weight:
By 400 parts of strangle careless, the root bark of white mulberry, 20 parts of pig's bile, 400 parts of Herba portulacae, 75 parts of sealwort, 50 parts of reed rhizome, 60 parts of the bletilla striata.
Preparation of the present invention is to press the obtainable preparation of prior art in the production of all Chinese medicines:Including capsule, particle
Agent, tablet, pill or oral solutions.
In the above-mentioned technical solutions, each taste Chinese medicine in compositing formula has following effect:
The invention is mainly made up of 7 kinds of Chinese medicines, and wherein Herba portulacae, strangle careless are fresh goods, and the two dosage is identical, wherein, Herba portulacae and
The preferable scheme of strangle careless is to use fresh goods, fresh goods in technical scheme dosage be 400 parts, dry product dosage be 200 parts, the present invention with
Herba portulacae, strangle careless are key agents, and Herba portulacae and strangle careless play the role of clearing heat and detoxicating!But the present invention is in treatment mouth disease
In certainly not select its clearing heat and detoxicating effect, in clinical practice, inventor has found other clearing heat and detoxicating treatment by Chinese herbs
Oral cavity oral peculiar smell effect is simultaneously bad!And inventor has found that Herba portulacae juice is sticky, orally gets up not dry strong, no other drugs
Side effect.Strangle careless herb thorn is more, can stretch muscle dredging collateral, can play a part of cleaning to tongue body and oral cavity, and Herba portulacae and strangle careless are made
For common monarch drug in a prescription, main function is played.The root bark of white mulberry aids in the effect of Herba portulacae and strangle careless, sealwort as ministerial drug lung heat clearing away, sputum eliminating
Nourishing stomach-YIN, its act on it is not dry do not moisten, be adjutant.Reed rhizome, bletilla striata clearing heat and promoting fluid and convergence, one clear one receives, the two compatibility, in meeting
The theory of doctor's lifting folding, is adjutant.Pig's bile is makes, and clearing gallbladder heat promotees digestion, is acted in we obvious!
The present invention is that medicine does not have toxic side effect in itself obtained from being developed, processed according to local genunie medicinal materials, developing,
Wherein, Herba portulacae and strangle careless are thick on the ground in the local of applicant, are disposed as weeds, and material is comparatively inexpensive, everywhere
It can pluck, strangle careless is removed as to the harmful crop of agricultural!Its production method of the invention is simple and easy simultaneously, conventional to add
Work method is used in the production of bulk drug provided by the invention, and cost of material is cheap, is readily obtained.
Traditional medicine thinks this interpretation of the cause, onset and process of an illness category liver and gall heat symptom-complex, stomach heat symptom-complex, damp heat in the spleen and the stomach strongly fragrant resistance, accumulates in liver and spleen convulsive seizure due to phlegm-fire, kidney
Asthenic yin, irascibility is partially prosperous, stomach energy etc., with the above mentioned technical proposal.Inventor started to apply institute of the present invention before the several years
The technical scheme stated, hundreds oral peculiar smell patient is treated, includes sticky in halitosis, mouth, the hot sense of tongue, bitter taste, mouth sweet tea, mouth
It is light, mouth is sour, obtain the effect of fine.
Embodiment:
The first:Take 400 parts of strangle careless, the root bark of white mulberry, 20 parts of pig's bile, 400 parts of Herba portulacae, 75 parts of sealwort, 50 parts of reed rhizome, the bletilla striata 60
Part.Wherein strangle careless, Herba portulacae are fresh goods, first decoct 20 minutes, add remaining medicine, continue to decoct 20 minutes.By above-mentioned original
Material medicine is fried into decoction and taken, and one portion per day, is divided into and taking twice sooner or later, even served to improvement or recovery from illness.
Second:By weight:50 parts of strangle careless, 50 parts of the root bark of white mulberry, 10 parts of pig's bile, 50 parts of Herba portulacae, 30 parts of sealwort, reed
10 parts of root, 20 parts of the bletilla striata.Wherein strangle careless, Herba portulacae are fresh goods, first decoct 20 minutes, add remaining medicine, continue decoction 20
Minute.Above-mentioned raw materials medicine is fried into decoction to take, one portion per day, is divided into and taking twice sooner or later, even served to improvement or recovery from illness.
The third:By weight:200 parts of strangle careless, 150 parts of the root bark of white mulberry, 15 parts of pig's bile, 200 parts of Herba portulacae, 50 parts of sealwort, reed
30 parts of root, 40 parts of the bletilla striata.Wherein strangle careless, Herba portulacae are fresh goods, first decoct 20 minutes, add remaining medicine, continue decoction 20
Minute.Above-mentioned raw materials medicine is fried into decoction to take, one portion per day, is divided into and taking twice sooner or later, even served to improvement or recovery from illness.
4th kind:By weight:100 parts of strangle careless, 75 parts of the root bark of white mulberry, 15 parts of pig's bile, 100 parts of Herba portulacae, 35 parts of sealwort, reed rhizome
20 parts, 25 parts of the bletilla striata.Wherein strangle careless, Herba portulacae are fresh goods, first decoct 20 minutes, add remaining medicine, continue to decoct 20 points
Clock.Above-mentioned raw materials medicine is fried into decoction to take, one portion per day, is divided into and taking twice sooner or later, even served to improvement or recovery from illness.
5th kind:By weight:Take 200 parts of strangle careless, 100 parts of the root bark of white mulberry, 20 parts of pig's bile, 200 parts of Herba portulacae, 75 parts of sealwort,
50 parts of reed rhizome, 60 parts of the bletilla striata.Wherein strangle careless, Herba portulacae are dry product, with remaining medicine co-grinding in 80-100 mesh, 2 times a day,
It is divided into and takes twice sooner or later, even served to improvement or recovery from illness.
Clinical practice:
1 clinical data
The present invention treats in canker sore 64, halitosis patient 35, mouthful sticky 9, tongue hot sense 15, bitter taste 27, mouthful
Light 5, mouthful acid 3 of sweet tea 6, mouthful, tongue thick,yellow and greasy fur 7, fissured tongue 3, is cured.
Chinese medicine composition provided by the present invention is described further with reference to the specific case in embodiment.
Embodiment 1:Female, 61 years old, intractable oral cavity ulcer, recurrent exerbation, the tip of the tongue and buccal aspect portion occurred white during breaking-out
Color ulcer point, gradually increase, pain is annual to break out 1-2 times, after examining, takes Chinese medicine composition decoction provided by the present invention
After 6 pairs, hence it is evident that take a turn for the better.Continue to take the pair of Chinese medicine composition 24, canker sore takes a turn for the better again without recurrence.
The patient take Chinese medicine composition material medicine proportioning be:Strangle careless 50g, root bark of white mulberry 50g, pig's bile 10g,
Herba portulacae 50g, sealwort 30g, reed rhizome 10g, bletilla striata 20g.
The man of embodiment 2,58 years old, canker sore, recurrent exerbation, occur it is latter as use aerosol therapy, slightly take a turn for the better, examine
Breaking, it is recurrent oral ulceration.After examining, after taking the pair of Chinese medicine composition decoction 3 provided by the present invention, hence it is evident that take a turn for the better.
Continue to take the pair of Chinese medicine composition 18, canker sore takes a turn for the better again without recurrence.
The patient take Chinese medicine composition material medicine proportioning be:Strangle careless 50g, root bark of white mulberry 30g, pig's bile 6g, horse
Tooth bamboo water pipe 50g, sealwort 20g, reed rhizome 10g, bletilla striata 10g.
The female of embodiment 3,43 years old, canker sore, during breaking-out, ulcer surface pain, it is difficult to feed, take the present invention and carried
After the pair of Chinese medicine composition decoction 6 of confession, hence it is evident that take a turn for the better.Continue to take the Chinese traditional medicine composition composition powders 1 month, canker sore takes a turn for the better
Again without recurrence.
The patient take Chinese medicine composition material medicine proportioning be:100 parts of strangle careless, 75 parts of the root bark of white mulberry, pig's bile 15
Part, 100 parts of Herba portulacae, 35 parts of sealwort, 20 parts of reed rhizome, 25 parts of the bletilla striata.
The effect of being present invention treatment halitosis below, is observed:
The patient of control group uses chlorine-containing compound mouthwash.Present invention side is fried by systematic unity of boiling medicine, and every dose of medicine is decocted into
200mL, usage:Gargle, contain 1-5 minutes, decoction is swallowed, observing effect after continuous 3 courses for the treatment of.
3 curative effect judging standards
It is effective:Halitosis symptom disappears, effectively:Halitosis symptom is improved in varying degrees, invalid:Halitosis symptom is without improvement.
4 results
Effect is as follows after two groups of patients, 3 courses for the treatment of:
Two groups of pretherapy and post-treatment effects compare(x±s)
The effective enabledisable obvious effective rate of group(%)
Treatment group(n =40) 35 5 0 87.5
Control group(n =40) 18 10 12 48
Note:Compared with after control group treatmentP<0.05。
In a word, halitosis is treated with the invention, it is curative for effect directly against the interpretation of the cause, onset and process of an illness of this disease, have no toxic side effect, have wide
Market prospects, be a project being worthy to be popularized.
Claims (3)
1. a kind of Chinese medicine preparation for treating oral peculiar smell, it is characterised by:The Chinese medicine preparation by following parts by weight former material
Material is made:
By strangle careless 50-400 parts, root bark of white mulberry 50-250 parts, pig's bile 10-20 parts, Herba portulacae 50-400 parts, sealwort 30-75 parts, reed
Root 10-50 parts, bletilla striata 20-60 parts.
2. the Chinese medicine preparation for the treatment of oral peculiar smell as claimed in claim 1, it is characterised by:The Chinese medicine preparation is by following heavy
The raw material of amount part are made:
By 400 parts of strangle careless, the root bark of white mulberry, 20 parts of pig's bile, 400 parts of Herba portulacae, 75 parts of sealwort, 50 parts of reed rhizome, 60 parts of the bletilla striata.
3. treating the Chinese medicine preparation of oral peculiar smell as described in claim 1 and 2, it is characterised by:The Chinese medicine preparation is institute
Have in Chinese medicine production by the obtainable preparation of prior art:Capsule, gargle, granule, tablet, pill or oral solutions.
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103610986A (en) * | 2013-12-06 | 2014-03-05 | 山东省立医院 | Medicine for treating ozostomia |
CN105362746A (en) * | 2015-11-25 | 2016-03-02 | 禤燕华 | Traditional Chinese medicine composition for halitosis treatment and preparation method of traditional Chinese medicine composition for halitosis treatment |
CN105709105A (en) * | 2016-04-07 | 2016-06-29 | 四川省中医药科学院 | Composition with function of clearing peculiar smell in oral cavity and preparation method of composition |
-
2017
- 2017-12-26 CN CN201711431429.6A patent/CN107789535A/en not_active Withdrawn
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103610986A (en) * | 2013-12-06 | 2014-03-05 | 山东省立医院 | Medicine for treating ozostomia |
CN105362746A (en) * | 2015-11-25 | 2016-03-02 | 禤燕华 | Traditional Chinese medicine composition for halitosis treatment and preparation method of traditional Chinese medicine composition for halitosis treatment |
CN105709105A (en) * | 2016-04-07 | 2016-06-29 | 四川省中医药科学院 | Composition with function of clearing peculiar smell in oral cavity and preparation method of composition |
Non-Patent Citations (2)
Title |
---|
刘有缘: "《一两味中药祛顽疾》", 31 August 2016, 山西科学技术出版社 * |
赵子城等: "以芳香化浊清热法为主治疗口臭报告", 《黑龙江中医药》 * |
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