CN107772443A - A kind of functional health-care food - Google Patents
A kind of functional health-care food Download PDFInfo
- Publication number
- CN107772443A CN107772443A CN201610729240.4A CN201610729240A CN107772443A CN 107772443 A CN107772443 A CN 107772443A CN 201610729240 A CN201610729240 A CN 201610729240A CN 107772443 A CN107772443 A CN 107772443A
- Authority
- CN
- China
- Prior art keywords
- functional health
- care food
- superoxide dismutase
- health
- capsule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000013305 food Nutrition 0.000 title claims abstract description 30
- 102000019197 Superoxide Dismutase Human genes 0.000 claims abstract description 35
- 108010012715 Superoxide dismutase Proteins 0.000 claims abstract description 35
- 239000000843 powder Substances 0.000 claims abstract description 20
- 229920001661 Chitosan Polymers 0.000 claims abstract description 16
- 102000004190 Enzymes Human genes 0.000 claims abstract description 10
- 108090000790 Enzymes Proteins 0.000 claims abstract description 10
- 238000002360 preparation method Methods 0.000 claims abstract description 8
- 238000007711 solidification Methods 0.000 claims abstract description 8
- 230000008023 solidification Effects 0.000 claims abstract description 8
- 235000013402 health food Nutrition 0.000 claims abstract description 7
- 239000000546 pharmaceutical excipient Substances 0.000 claims abstract description 4
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims description 26
- 239000002775 capsule Substances 0.000 claims description 15
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims description 14
- 239000008108 microcrystalline cellulose Substances 0.000 claims description 14
- 229940016286 microcrystalline cellulose Drugs 0.000 claims description 14
- 239000011734 sodium Substances 0.000 claims description 14
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims description 13
- 235000019359 magnesium stearate Nutrition 0.000 claims description 13
- 229920002472 Starch Polymers 0.000 claims description 12
- 229910052708 sodium Inorganic materials 0.000 claims description 12
- 239000008107 starch Substances 0.000 claims description 12
- 235000019698 starch Nutrition 0.000 claims description 12
- 239000000463 material Substances 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 6
- 239000002245 particle Substances 0.000 claims description 5
- 238000003756 stirring Methods 0.000 claims description 5
- 239000003643 water by type Substances 0.000 claims description 5
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 4
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 claims description 4
- 239000000945 filler Substances 0.000 claims description 4
- 239000000314 lubricant Substances 0.000 claims description 4
- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 claims description 3
- 239000007884 disintegrant Substances 0.000 claims description 3
- GUBGYTABKSRVRQ-QKKXKWKRSA-N lactose group Chemical group OC1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@H](O2)CO)[C@H](O1)CO GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims description 3
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims description 2
- 239000004375 Dextrin Substances 0.000 claims description 2
- 229920001353 Dextrin Polymers 0.000 claims description 2
- 229930195725 Mannitol Natural products 0.000 claims description 2
- 235000011132 calcium sulphate Nutrition 0.000 claims description 2
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims description 2
- 235000019425 dextrin Nutrition 0.000 claims description 2
- MVPICKVDHDWCJQ-UHFFFAOYSA-N ethyl 3-pyrrolidin-1-ylpropanoate Chemical compound CCOC(=O)CCN1CCCC1 MVPICKVDHDWCJQ-UHFFFAOYSA-N 0.000 claims description 2
- 239000008101 lactose Substances 0.000 claims description 2
- 239000000594 mannitol Substances 0.000 claims description 2
- 235000010355 mannitol Nutrition 0.000 claims description 2
- 239000000741 silica gel Substances 0.000 claims description 2
- 229910002027 silica gel Inorganic materials 0.000 claims description 2
- 229940045902 sodium stearyl fumarate Drugs 0.000 claims description 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical group [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 claims 1
- 238000004132 cross linking Methods 0.000 claims 1
- 150000002576 ketones Chemical class 0.000 claims 1
- 229940031703 low substituted hydroxypropyl cellulose Drugs 0.000 claims 1
- 239000013049 sediment Substances 0.000 claims 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims 1
- 229940100691 oral capsule Drugs 0.000 abstract description 2
- 230000002779 inactivation Effects 0.000 abstract 1
- 230000008859 change Effects 0.000 description 8
- 229940032147 starch Drugs 0.000 description 8
- OUUQCZGPVNCOIJ-UHFFFAOYSA-M Superoxide Chemical compound [O-][O] OUUQCZGPVNCOIJ-UHFFFAOYSA-M 0.000 description 7
- 229910052760 oxygen Inorganic materials 0.000 description 4
- 239000001301 oxygen Substances 0.000 description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 229940080313 sodium starch Drugs 0.000 description 3
- 238000001291 vacuum drying Methods 0.000 description 3
- -1 EC1.15.1.1 Proteins 0.000 description 2
- 208000005374 Poisoning Diseases 0.000 description 2
- 230000003712 anti-aging effect Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 108010070915 orgotein Proteins 0.000 description 2
- 229960004534 orgotein Drugs 0.000 description 2
- 231100000572 poisoning Toxicity 0.000 description 2
- 230000000607 poisoning effect Effects 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 230000005855 radiation Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- TUGDLVFMIQZYPA-UHFFFAOYSA-N tetracopper;tetrazinc Chemical compound [Cu+2].[Cu+2].[Cu+2].[Cu+2].[Zn+2].[Zn+2].[Zn+2].[Zn+2] TUGDLVFMIQZYPA-UHFFFAOYSA-N 0.000 description 2
- 208000023275 Autoimmune disease Diseases 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 208000002177 Cataract Diseases 0.000 description 1
- 206010014561 Emphysema Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 241000270295 Serpentes Species 0.000 description 1
- 239000011149 active material Substances 0.000 description 1
- 208000038016 acute inflammation Diseases 0.000 description 1
- 230000006022 acute inflammation Effects 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 229940095672 calcium sulfate Drugs 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 239000000490 cosmetic additive Substances 0.000 description 1
- 235000021245 dietary protein Nutrition 0.000 description 1
- 210000002249 digestive system Anatomy 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 229960001375 lactose Drugs 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 235000013809 polyvinylpolypyrrolidone Nutrition 0.000 description 1
- 229920000523 polyvinylpolypyrrolidone Polymers 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 239000002516 radical scavenger Substances 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 239000008279 sol Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses a kind of functional health-care food, it is characterised in that the health food includes superoxide dismutase and pharmaceutic adjuvant.Because superoxide dismutase is a kind of enzyme of bioactivity, the shortcomings of its stability is poor, easy in inactivation, half-life short is difficult to preserve, the present invention is made for oral capsule preparations after superoxide dismutase is carried out into parcel solidification as carrier by the use of chitosan powder, not only dosage is accurate, and its stability can be increased substantially, storage is convenient.
Description
Technical field
The invention belongs to field of health care food, and in particular to a kind of functional health-care food of superoxide dismutase.
Background technology
Superoxide dismutase Orgotein (Superoxide Dismutase, SOD), alias orgotein, abbreviation：
SOD.SOD is a kind of active material for coming from life entity, can eliminate organism caused harmful substance in metabolic processes.
Constantly supplementing human body SOD has the special-effect of anti-aging.Superoxide dismutase（Superoxide Dismutase,
EC1.15.1.1, SOD）It is to be counted first since ox red blood cell isolated superoxide dismutase for 1938, people couple
SOD research oneself have the history of more than 70 years.McCord in 1969 etc. rediscovers this albumen, and it was found that their life
Thing activity, understand fully that it is catalyzed the property that disproportionated reaction occurs for superoxide anion, so being formally named as superoxides discrimination
Change enzyme.
SOD is the natural scavenger of oxygen radical in organism, has extensive medical value, can be used as medicine, food
And the additive of daily chemical products.Following disease clinically can be treated and prevented with SOD：Acute inflammation and oedema, oxygen poisoning prevention
（Precautionary measures, into the staff of hyperbaric oxygen chamber, SOD can be injected in advance）, oxygen poisoning treatment, autoimmune disease（It is early
Phase treats）, pulmonary emphysema, Radiation sickness and radiation protection, cataract of old people, anti-aging.
In terms of superoxide dismutase is widely used in cosmetic additive agent, as manufactured using superoxide dismutase
The cosmetics such as SOD facial masks, SOD honey, SOD snake powder, do not have hundreds of products at present.
For SOD by as a kind of supplements, people think that feasible methods various to the greatest extent make SOD remain higher in human body
Level, i.e., while food is consumed, there is provided suitable nutrition supplying liver synthesis SOD, or be directly wrapped in external source SOD
In food protein, through digestive system without being digested, into body other positions.
The content of the invention
A kind of the present invention is intended to provide superoxide dismutase capsule that dosage is accurate, storage is convenient, stability is good.
For achieving the above object, a kind of functional health-care food of the present invention, concrete scheme are：
A kind of functional health-care food of the present invention, it is characterised in that the health food includes superoxide dismutase and medicine
With auxiliary material, the health food is carrier using chitosan powder, and superoxide dismutase is carried out into preparation after parcel solidification.
A kind of functional health-care food of the present invention, pharmaceutic adjuvant described in the health food include filler, disintegrant,
Lubricant.
A kind of functional health-care food of the present invention, the filler be lactose, starch, microcrystalline cellulose, calcium sulfate,
One kind, two or more composition in pre-paying starch, mannitol or dextrin；The disintegrant is carboxymethyl cellulose
Plain sodium, Ac-Di-Sol, sodium carboxymethyl starch, CCMS-Na, PVPP or low-substituted hydroxypropyl are fine
One kind, two or more composition in dimension element；The label lubricant is superfine silica gel powder, talcum powder, magnesium stearate
Or one kind in sodium stearyl fumarate, two or more composition.
A kind of functional health-care food of the present invention, the functional health-care food are capsule.
A kind of functional health-care food of the present invention, the functional health-care food capsule prescription are：Superoxides discrimination
Change enzyme, chitosan powder, microcrystalline cellulose PH102, sodium carboxymethyl starch, magnesium stearate.
A kind of functional health-care food of the present invention, the functional health-care food capsule prescription are：Superoxides discrimination
Change enzyme 600000IU, microcrystalline cellulose 200g ~ 280g, chitosan powder 3.0g ~ 10.0g, sodium carboxymethyl starch 5.0g ~ 20.0g,
Magnesium stearate 0.5g ~ 3g.
A kind of functional health-care food of the present invention, the functional health-care food capsule preparation method thereof are：
1）Take the superoxide dismutase of recipe quantity to be added in 100ml purified waters to dissolve, pour into the chitosan powder of recipe quantity, fill
Stirring well for dividing is even, with being filtered after placing 10 hours at a temperature of 4 DEG C, 40 DEG C of superoxide dismutases solidified after being dried in vacuo
Enzyme；
2）By step 1）In obtain solidification superoxide dismutase and recipe quantity microcrystalline cellulose PH102 and CMS
Sodium is well mixed；
3）The above-mentioned material mixed is added into magnesium stearate to be well mixed；
4）By grain weight 300mg by it is particles filled enter capsule in, produce.
The advantage of the invention is that：Superoxide dismutase is a kind of enzyme of bioactivity, because its stability is poor, volatile
The shortcomings of work, half-life short, is difficult to preserve, and superoxide dismutase by the use of chitosan powder as carrier wrap up admittedly by this patent
It is made after change for oral capsule preparations, not only dosage is accurate, and can increase substantially its stability, and storage is convenient.
Embodiment
Example below is only of the invention to further illustrate, scope that the invention is not limited in any way.
Embodiment 1
Prescription：
Superoxide dismutase 600000IU
Chitosan powder 5g
Microcrystalline cellulose PH102 250g
Sodium carboxymethyl starch 12g
Magnesium stearate 2g
1000 are made altogether
Preparation method：
（1）Take the superoxide dismutase of recipe quantity to be added in 100ml purified waters to dissolve, pour into the chitosan powder of recipe quantity,
Sufficiently stir well it is even, with being filtered after placing 10 hours at a temperature of 4 DEG C, the superoxides discriminations that are solidified after 40 DEG C of vacuum drying
Change enzyme.
（2）By step（1）In obtain solidification superoxide dismutase and recipe quantity microcrystalline cellulose PH102 and carboxylic first
Base sodium starch is well mixed.
（3）The above-mentioned material mixed is added into magnesium stearate to be well mixed.
（4）By grain weight 300mg by it is particles filled enter capsule in, produce.
Embodiment 2
Prescription：
Superoxide dismutase 600000IU
Chitosan powder 10g
Microcrystalline cellulose PH102 200g
Sodium carboxymethyl starch 20g
Magnesium stearate 0.5g
1000 are made altogether
Preparation method：
（1）Take the superoxide dismutase of recipe quantity to be added in 100ml purified waters to dissolve, pour into the chitosan powder of recipe quantity,
Sufficiently stir well it is even, with being filtered after placing 10 hours at a temperature of 4 DEG C, the superoxides discriminations that are solidified after 40 DEG C of vacuum drying
Change enzyme.
（2）By step（1）In obtain solidification superoxide dismutase and recipe quantity microcrystalline cellulose PH102 and carboxylic first
Base sodium starch is well mixed.
（3）The above-mentioned material mixed is added into magnesium stearate to be well mixed.
（4）By grain weight 300mg by it is particles filled enter capsule in, produce.
Embodiment 3
Prescription：
Superoxide dismutase 600000IU
Chitosan powder 3g
Microcrystalline cellulose PH102 280g
Sodium carboxymethyl starch 5g
Talcum powder 1g
Silica 2g
1000 are made altogether
Preparation method：
（1）Take the superoxide dismutase of recipe quantity to be added in 100ml purified waters to dissolve, pour into the chitosan powder of recipe quantity,
Sufficiently stir well it is even, with being filtered after placing 10 hours at a temperature of 4 DEG C, the superoxides discriminations that are solidified after 40 DEG C of vacuum drying
Change enzyme.
（2）By step（1）In obtain solidification superoxide dismutase and recipe quantity microcrystalline cellulose PH102 and carboxylic first
Base sodium starch is well mixed.
（3）The above-mentioned material mixed is added into magnesium stearate to be well mixed.
（4）By grain weight 300mg by it is particles filled enter capsule in, produce.
Experimental example：Stability experiment
1. accelerated test data（Embodiment 1）：
2. accelerated test data（Embodiment 2）
3. accelerated test data（Embodiment 3）
Result above shows that under these conditions, sample property and content illustrate that the prescription and technique can be very without significant change
The stability of medicine is improved well.
Claims (7)
1. a kind of functional health-care food, it is characterised in that the health food includes superoxide dismutase and pharmaceutic adjuvant, should
Health food is carrier using chitosan powder, and capsule is made after superoxide dismutase is carried out into parcel solidification.
A kind of 2. functional health-care food according to claim 1, it is characterised in that pharmaceutic adjuvant bag described in the health food
Include filler, disintegrant, lubricant.
3. a kind of functional health-care food according to claim 2, it is characterised in that the filler is lactose, starch, micro-
Crystalline cellulose, calcium sulfate, pre-paying starch, mannitol or one kind in dextrin, two or more composition；It is described to collapse
Solution agent is sodium carboxymethylcellulose, Ac-Di-Sol, sodium carboxymethyl starch, CCMS-Na, the poly- dimension of crosslinking
One kind, two or more composition in ketone or low-substituted hydroxypropyl cellulose；The label lubricant be superfine silica gel powder,
One kind, two or more composition in talcum powder, magnesium stearate or sodium stearyl fumarate.
4. according to a kind of any one of claim 1-3 functional health-care foods, it is characterised in that the functional health-care food
For capsule.
5. a kind of functional health-care food according to claim 4, it is characterised in that at the functional health-care food capsule
Fang Wei：Superoxide dismutase, chitosan powder, microcrystalline cellulose PH102, sodium carboxymethyl starch, magnesium stearate.
6. a kind of functional health-care food according to claim 5, it is characterised in that at the functional health-care food capsule
Fang Wei：Superoxide dismutase 600000IU, microcrystalline cellulose 200g ~ 280g, chitosan powder 3.0g ~ 10.0g, carboxymethyl form sediment
Powder sodium 5.0g ~ 20.0g, magnesium stearate 0.5g ~ 3g.
A kind of 7. functional health-care food according to claim 6, it is characterised in that the functional health-care food capsule system
Preparation Method is：
1）Take the superoxide dismutase of recipe quantity to be added in 100ml purified waters to dissolve, pour into the chitosan powder of recipe quantity, fill
Stirring well for dividing is even, with being filtered after placing 10 hours at a temperature of 4 DEG C, 40 DEG C of superoxide dismutases solidified after being dried in vacuo
Enzyme；
2）By step 1）In obtain solidification superoxide dismutase and recipe quantity microcrystalline cellulose PH102 and CMS
Sodium is well mixed；
3）The above-mentioned material mixed is added into magnesium stearate to be well mixed；
4）By grain weight 300mg by it is particles filled enter capsule in, produce.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610729240.4A CN107772443A (en) | 2016-08-26 | 2016-08-26 | A kind of functional health-care food |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610729240.4A CN107772443A (en) | 2016-08-26 | 2016-08-26 | A kind of functional health-care food |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107772443A true CN107772443A (en) | 2018-03-09 |
Family
ID=61439725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610729240.4A Pending CN107772443A (en) | 2016-08-26 | 2016-08-26 | A kind of functional health-care food |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107772443A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995002968A1 (en) * | 1993-07-26 | 1995-02-02 | Shichiro Niwano | Processed food comprising leaves of panax ginseng c.a. meyer and process for producing the same |
| CN1102590A (en) * | 1993-11-10 | 1995-05-17 | 徐州市老年病研究所 | Intestine dissolvable SOD preparation and its production |
| CN101590223A (en) * | 2008-05-26 | 2009-12-02 | 刘安荣 | A kind of SOD complex capsule and preparation method thereof |
-
2016
- 2016-08-26 CN CN201610729240.4A patent/CN107772443A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995002968A1 (en) * | 1993-07-26 | 1995-02-02 | Shichiro Niwano | Processed food comprising leaves of panax ginseng c.a. meyer and process for producing the same |
| CN1102590A (en) * | 1993-11-10 | 1995-05-17 | 徐州市老年病研究所 | Intestine dissolvable SOD preparation and its production |
| CN101590223A (en) * | 2008-05-26 | 2009-12-02 | 刘安荣 | A kind of SOD complex capsule and preparation method thereof |
Non-Patent Citations (5)
| Title |
|---|
| 徐小静等主编: "《生物技术原理与实验》", 31 July 2006, 中央民族大学出版社 * |
| 方亮主编: "《药剂学》", 31 March 2016, 中国医药科技出版社 * |
| 李志国等: ""固定化脂肪酶的动力学研究"", 《华东理工大学学报》 * |
| 李磊等: ""超氧化物歧化酶的固定化及其酶学性质"", 《中国生物制品学杂志》 * |
| 杜秀园主编: "《胶囊剂生产与检测技术》", 31 December 2015, 中央广播电视大学出版社 * |
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180309 |
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