CN107753158A - Strengthen the preceding road vertebral body prosthesis device of osteogenesis type homogeneous allogenic bone - Google Patents
Strengthen the preceding road vertebral body prosthesis device of osteogenesis type homogeneous allogenic bone Download PDFInfo
- Publication number
- CN107753158A CN107753158A CN201711106680.5A CN201711106680A CN107753158A CN 107753158 A CN107753158 A CN 107753158A CN 201711106680 A CN201711106680 A CN 201711106680A CN 107753158 A CN107753158 A CN 107753158A
- Authority
- CN
- China
- Prior art keywords
- bone
- vertebral body
- prosthesis device
- body prosthesis
- filling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2002/2835—Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00359—Bone or bony tissue
Abstract
The invention discloses one kind to strengthen the preceding road vertebral body prosthesis device of osteogenesis type homogeneous allogenic bone, including vertebral body prosthesis device body and the filling bone piece being closely embedded in the filling hole being opened on vertebral body prosthesis device body, the height of the filling bone piece is less than or equal to the height in filling hole, the material of the vertebral body prosthesis device body is homogeneous allogenic bone, and the material of the filling bone piece is cancellous bone.Biocompatibility and bone formation performance of the present invention are good, and have enough mechanical strengths to meet the requirement for supporting corresponding site to mechanics.
Description
Technical field
The invention belongs to medical bio implantation material and technical field of medical instruments, and in particular to it is same that one kind strengthens osteogenesis type
The kind preceding road intervertenral space fusion device of allograph bone and vertebral body prosthesis device, suitable for the preceding road neck of homogeneous allogenic bone, Thoracolumbar disk vertebral body prosthesis.
Background technology
Vertebral body prosthesis device is applied to cervical vertebra, Thoracolumbar disk body bone grafting is rebuild and fusion.Vertebral body prosthesis device type is a lot, mainly has
The materials such as TC4 titanium alloys, polyether-ether-ketone (PEEK) polymeric material, bioceramic are made, in operation, for raising knitting
Caused syncretizing effect, in the product portion's hollow out intracavitary filling autologous bone, make fusion device produce mechanical support effect, implantation from
The knitting of body ostosis and reach interpyramidal fusion.But there are problems and deficiency in this tradition filling amalgamation mode
Place, it is specifically：1st, the material such as metal, high polymer material, bioceramic is made fusion device and vertebral body prosthesis device, biocompatibility compared with
Allogeneic bone material is poor, and modulus of elasticity and human body bone are inconsistent, and these materials can not form new skeletonization in itself, often also not
It can degrade and be substituted by itself bone；2nd, autologous bone materials are limited, are such as cut from the other positions of patient itself and may trigger Qu Gu areas simultaneously
The defects of sending out disease；Autologous bone is packed into the bone grafting chamber of hollow out, the trouble operated in increase operation when the 3rd, performing the operation, and cut in performing the operation
The shape of the autologous bone taken is often irregular, is not matched that with the bone grafting chamber of fusion device hollow out, causes bone grafting effect impacted, melts
It is poor to close effect.
The content of the invention
It is an object of the invention to provide one kind to strengthen the preceding road vertebral body prosthesis device of osteogenesis type homogeneous allogenic bone, its bio-compatible
Property and bone formation performance it is good, and with enough mechanical strengths to meet to support requirement of the corresponding site to mechanics.
The technical solution adopted for the present invention to solve the technical problems is：
One kind strengthens the preceding road vertebral body prosthesis device of osteogenesis type homogeneous allogenic bone, and the vertebral body prosthesis device includes vertebral body prosthesis device body
The filling bone piece being closely embedded in the filling hole being opened on vertebral body prosthesis device body, the height of the filling bone piece are less than
Or the height equal to filling hole, the material of the vertebral body prosthesis device body is homogeneous allogenic bone, and the material of the filling bone piece is
Cancellous bone.
By above-mentioned technical proposal, the material of the vertebral body prosthesis device body is cortex bone.
By above-mentioned technical proposal, the vertebral body prosthesis device body carries out surface decalcification processing.
By above-mentioned technical proposal, the vertebral body prosthesis device body is through removing marrow, degreasing, de- cell, surface decalcification work
The vertebral body prosthesis device body formed after skill processing after freeze-drying, vacuum packaging through irradiation sterilization.
By above-mentioned technical proposal, the filling bone piece is through at removing marrow, degreasing, de- cell, removing immunogene technique
The filling bone piece for being freeze-dried after reason, being formed after vacuum packaging through irradiation sterilization.
The beneficial effect comprise that：Vertebral body prosthesis device provided by the invention, its body use homogeneous allogenic bone root
Designed and produced according to the requirement of implant site anatomical structure, the mechanical property and people's bone of homogeneous allogenic bone are completely the same, will not be as other
Material, which can cut cartilage endplate, causes disc height to reduce, good biocompatibility, and mechanical strength meets support corresponding site pair
The requirement of mechanics, and the histological change process evolution of " creeping substitution " can be had stepped through into the bone tissue of patient oneself
Reach and strengthen the purpose of fusion；Meanwhile by filling the tightly packed filling bone piece made by cancellous bone in hole in body,
Bone contact surface early stage forms new bone by osteoacusis mode above and below can making, and reaches knitting and fusion purpose.The present invention is by same
Kind allosome bone material is process, and is avoided and is cut the defects of autologous bone brings complication, and can directly plant when in use
Enter, it is not necessary to carry out the bone grafting filling of fusion device or displacer again.
Brief description of the drawings
Below in conjunction with drawings and Examples, the invention will be further described, in accompanying drawing：
Fig. 1 is the structural representation of the embodiment of the present invention；
Fig. 2 is the exploded view of the embodiment of the present invention.
In figure：3- vertebral body prosthesis devices body, 301- fillings hole, 4- filling bone pieces.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, it is right below in conjunction with drawings and Examples
The present invention is further elaborated.It should be appreciated that specific embodiment described herein is only to explain the present invention, not
For limiting the present invention.As shown in Figure 1 and Figure 2, a kind of to strengthen the preceding road vertebral body prosthesis device of osteogenesis type homogeneous allogenic bone, the centrum is put
Parallel operation includes vertebral body prosthesis device body 3 and the filling being closely embedded in the filling hole 301 being opened on vertebral body prosthesis device body 3
Bone piece 4, the height of filling bone piece 4 are less than or equal to the height in filling hole 301, and the material of vertebral body prosthesis device body 3 is of the same race different
Body bone, the material of filling bone piece 4 is cancellous bone.
In a preferred embodiment of the invention, the material of vertebral body prosthesis device body is cortex bone, and cortex bone sclerotin is closely knit, power
It is good to learn intensity, product in agglutination is not collapsed.
In a preferred embodiment of the invention, vertebral body prosthesis device body undecalcified or surface decalcification, it carries out surface and taken off
Calcium treatment, certain induced osteogenesis ability can be produced, accelerate the fusion of vertebral body prosthesis device body.In the present embodiment, fusion device sheet
When residual calcium content is 8%-55% in vivo, its induced osteogenesis ability is optimal.
In a preferred embodiment of the invention, vertebral body prosthesis device body is to be taken off through removing marrow, degreasing, de- cell, surface
The vertebral body prosthesis device body for being freeze-dried after calcium PROCESS FOR TREATMENT, being formed after vacuum packaging through irradiation sterilization, good biocompatibility, nothing
Immunological rejection symptom occurs.
In a preferred embodiment of the invention, it is through removing marrow, degreasing, de- cell, removing immunogene work to fill bone piece
The filling bone piece formed after skill processing after freeze-drying, vacuum packaging through irradiation sterilization, good biocompatibility, no immunological rejection disease
Shape occurs.
It should be appreciated that for those of ordinary skills, can according to the above description be improved or converted,
And all these modifications and variations should all belong to the protection domain of appended claims of the present invention.
Claims (5)
1. one kind strengthens the preceding road vertebral body prosthesis device of osteogenesis type homogeneous allogenic bone, it is characterised in that the vertebral body prosthesis device includes centrum
Displacer body and the filling bone piece being closely embedded in the filling hole being opened on vertebral body prosthesis device body, the filling bone piece
Height be less than or equal to the height in filling hole, the material of the vertebral body prosthesis device body is homogeneous allogenic bone, the filling bone
The material of block is cancellous bone.
2. the reinforcement preceding road intervertenral space vertebral body prosthesis device of osteogenesis type homogeneous allogenic bone according to claim 1, it is characterised in that
The material of the vertebral body prosthesis device body is cortex bone.
3. the reinforcement preceding road intervertenral space vertebral body prosthesis device of osteogenesis type homogeneous allogenic bone according to claim 1, it is characterised in that
The vertebral body prosthesis device body carries out surface decalcification processing.
4. the reinforcement preceding road intervertenral space vertebral body prosthesis device of osteogenesis type homogeneous allogenic bone according to claim 1, it is characterised in that
The vertebral body prosthesis device body is freeze-drying, vacuum packet after removing marrow, degreasing, de- cell, surface decalcification PROCESS FOR TREATMENT
The vertebral body prosthesis device body formed after dress through irradiation sterilization.
5. the reinforcement preceding road intervertenral space vertebral body prosthesis device of osteogenesis type homogeneous allogenic bone according to claim 1, it is characterised in that
The bone piece of filling is to be freeze-dried, after vacuum packaging after removing marrow, degreasing, de- cell, removing immunogene PROCESS FOR TREATMENT
The irradiated filling bone piece formed that sterilizes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711106680.5A CN107753158A (en) | 2017-11-10 | 2017-11-10 | Strengthen the preceding road vertebral body prosthesis device of osteogenesis type homogeneous allogenic bone |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711106680.5A CN107753158A (en) | 2017-11-10 | 2017-11-10 | Strengthen the preceding road vertebral body prosthesis device of osteogenesis type homogeneous allogenic bone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107753158A true CN107753158A (en) | 2018-03-06 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711106680.5A Pending CN107753158A (en) | 2017-11-10 | 2017-11-10 | Strengthen the preceding road vertebral body prosthesis device of osteogenesis type homogeneous allogenic bone |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107753158A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020029084A1 (en) * | 1998-08-03 | 2002-03-07 | Paul David C. | Bone implants with central chambers |
| CN101164626A (en) * | 2007-10-16 | 2008-04-23 | 张旗 | Method for preparing degreasing sterilization deep-low temperature allograft bone and use |
| CN102551926A (en) * | 2012-02-09 | 2012-07-11 | 北京大清生物技术有限公司 | Lumbar fusion cage and manufacturing method thereof |
| CN209548151U (en) * | 2017-11-10 | 2019-10-29 | 湖北联结生物材料有限公司 | Reinforce the preceding road vertebral body prosthesis device of osteogenesis type homogeneous allogenic bone |
-
2017
- 2017-11-10 CN CN201711106680.5A patent/CN107753158A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020029084A1 (en) * | 1998-08-03 | 2002-03-07 | Paul David C. | Bone implants with central chambers |
| CN101164626A (en) * | 2007-10-16 | 2008-04-23 | 张旗 | Method for preparing degreasing sterilization deep-low temperature allograft bone and use |
| CN102551926A (en) * | 2012-02-09 | 2012-07-11 | 北京大清生物技术有限公司 | Lumbar fusion cage and manufacturing method thereof |
| CN209548151U (en) * | 2017-11-10 | 2019-10-29 | 湖北联结生物材料有限公司 | Reinforce the preceding road vertebral body prosthesis device of osteogenesis type homogeneous allogenic bone |
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