CN107712871A - Nutrition Co-Q10 powder and preparation method thereof - Google Patents
Nutrition Co-Q10 powder and preparation method thereof Download PDFInfo
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- 239000000843 powder Substances 0.000 title claims abstract description 94
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 title claims abstract description 89
- 235000016709 nutrition Nutrition 0.000 title claims abstract description 37
- 230000035764 nutrition Effects 0.000 title claims abstract description 37
- 238000002360 preparation method Methods 0.000 title claims abstract description 26
- 235000005976 Citrus sinensis Nutrition 0.000 claims abstract description 16
- 240000002319 Citrus sinensis Species 0.000 claims abstract description 16
- 229920002774 Maltodextrin Polymers 0.000 claims abstract description 15
- 239000005913 Maltodextrin Substances 0.000 claims abstract description 13
- 229940035034 maltodextrin Drugs 0.000 claims abstract description 13
- 239000003755 preservative agent Substances 0.000 claims abstract description 9
- 238000001694 spray drying Methods 0.000 claims abstract description 4
- 239000007788 liquid Substances 0.000 claims description 27
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 24
- 235000008390 olive oil Nutrition 0.000 claims description 23
- 239000004006 olive oil Substances 0.000 claims description 23
- 239000000839 emulsion Substances 0.000 claims description 16
- 238000003756 stirring Methods 0.000 claims description 15
- 229930003427 Vitamin E Natural products 0.000 claims description 12
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 12
- 235000019165 vitamin E Nutrition 0.000 claims description 12
- 229940046009 vitamin E Drugs 0.000 claims description 12
- 239000011709 vitamin E Substances 0.000 claims description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 11
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 claims description 10
- 235000010489 acacia gum Nutrition 0.000 claims description 9
- 239000001785 acacia senegal l. willd gum Substances 0.000 claims description 9
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- 235000017471 coenzyme Q10 Nutrition 0.000 description 11
- 229940110767 coenzyme Q10 Drugs 0.000 description 8
- HHEAADYXPMHMCT-UHFFFAOYSA-N dpph Chemical compound [O-][N+](=O)C1=CC([N+](=O)[O-])=CC([N+]([O-])=O)=C1[N]N(C=1C=CC=CC=1)C1=CC=CC=C1 HHEAADYXPMHMCT-UHFFFAOYSA-N 0.000 description 5
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- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
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- 241000190633 Cordyceps Species 0.000 description 1
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- GXCLVBGFBYZDAG-UHFFFAOYSA-N N-[2-(1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine Chemical compound CN(CCC1=CNC2=C1C=CC=C2)CC=C GXCLVBGFBYZDAG-UHFFFAOYSA-N 0.000 description 1
- 241000233855 Orchidaceae Species 0.000 description 1
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- 229930003448 Vitamin K Natural products 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 1
- PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000003130 cardiopathic effect Effects 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 239000005515 coenzyme Substances 0.000 description 1
- 208000029742 colonic neoplasm Diseases 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 230000035614 depigmentation Effects 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 235000019441 ethanol Nutrition 0.000 description 1
- 125000005909 ethyl alcohol group Chemical group 0.000 description 1
- 210000004700 fetal blood Anatomy 0.000 description 1
- 240000000971 garden vetch Species 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 230000000302 ischemic effect Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
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- 208000019423 liver disease Diseases 0.000 description 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 210000003470 mitochondria Anatomy 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 230000002107 myocardial effect Effects 0.000 description 1
- 230000004792 oxidative damage Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 210000000496 pancreas Anatomy 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 208000028169 periodontal disease Diseases 0.000 description 1
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 150000004053 quinones Chemical class 0.000 description 1
- NPCOQXAVBJJZBQ-UHFFFAOYSA-N reduced coenzyme Q9 Natural products COC1=C(O)C(C)=C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)C(O)=C1OC NPCOQXAVBJJZBQ-UHFFFAOYSA-N 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 229940035936 ubiquinone Drugs 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000019168 vitamin K Nutrition 0.000 description 1
- 239000011712 vitamin K Substances 0.000 description 1
- 150000003721 vitamin K derivatives Chemical class 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 229940046010 vitamin k Drugs 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a kind of nutrition Co-Q10 powder and preparation method thereof, its preparation method comprises the following steps：Co-Q10 powder, sweet orange powder, preservative agent, maltodextrin are well mixed and produced.The preparation method of nutrition Co-Q10 powder of the present invention, using microcapsules technology, with appropriate wall material to embedding, microencapsulation is carried out to Co-Q10 by spray drying process, can be to effectively improve its light, heat and oxidation stability, and its slow release effect in human body can be realized, effectively improve the bioavilability in human body.The nutrition Co-Q10 powder of the present invention between each composition by reasonably matching, not only tasty and refreshing, aromatic flavour, and has anti-oxidation health effect.
Description
Technical field
The present invention relates to technical field of health care food, and in particular to a kind of nutrition Co-Q10 powder and preparation method thereof.
Background technology
Co-Q10 is a kind of fat-soluble quinones, also known as ubiquinone, Q10, and its structure is similar to vitamin K,
It is a kind of biostearin material.Co-Q10 is widely present in intracellular, the especially enrichment of animals and plants and microorganism with extremely low content
In the mitochondria of mammal.The total content of human body coenzyme Q 10 is 0.5-1.5g, and in heart, liver, kidney and pancreas
It is distributed more.Along with the growth at age, the content of human body coenzyme Q 10 can be gradually decreased, it is necessary to be supplemented from the external world.
Popular name for clinical study results showed between past 20 years：It is most likely myocardial dysfunction type heart to lack Co-Q10
The primary pathogenesis of disease, it is the cardiopathic secondary pathogenic factor of other types to be also likely to；Detected for various cancer patients
As a result show：The metastases of the patients such as mastocarcinoma, prostate cancer, cancer of pancreas and colon cancer are inhibited, wherein there is minority
Case tumour disappears；Co-Q10 can effective strengthen immunity, Folkerse in 1985 etc. 8 are ended using Co-Q10
Grow patient to be treated, after one month, serum IgG content significantly improves, therefore Co-Q10 is as body nospecific immunity ratio
Strong agent can be used as a kind of preferable medicine in raising immunity of organisms etc.；Co-Q10 can prevent fat and protein
Peroxidating, free radical is removed, be used to reduce the oxidative damage of body tissue and as low-density lipoprotein (LDL) cholesterol oxygen
Change inhibitor.This shows that Co-Q10 has the function that to treat ischaemic and embolism and the potential for slowing down artery sclerosis.Coenzyme
Q10 antioxidation demonstrates free-radical theory again, and have clearly revealed chronic aging and the retrogression pathological changes of correlation
Mechanism；Co-Q10 has been successfully applied struggles with periodontal disease, particularly gum disease；Co-Q10 is in cosmetics
Using being also very extensive, Co-Q10 is referred to as the source in youth, for significantly putting down wrinkle, moisturizing in face cream and eye cream again, disappearing
The calm effect of depigmentation.
A large amount of clinical datas show that Co-Q10 is mainly used in treating heart disease, tumour, AIDS, hepatopathy, prevention presenile
Dementia, gum disease, anti-aging, health and beauty etc., are with a wide range of applications as health food.
The content of the invention
In order to solve the problems, such as that prior art is present, the invention provides a kind of nutrition Co-Q10 powder and preparation method thereof.
Technical scheme is as follows：
A kind of preparation method of nutrition Co-Q10 powder, comprises the following steps：
S1, by Co-Q10 powder, sweet orange powder, preservative agent, maltodextrin is well mixed produces.
A kind of preparation method of nutrition Co-Q10 powder, comprises the following steps：
S1, by 5-15 parts by weight Co-Q10s powder, 13-17 parts by weight sweet oranges powder, 0.03-0.06 parts by weight preservative agent, 78-
82 parts by weight maltodextrins are well mixed to be produced.
As an improvement technical scheme, a kind of preparation method of nutrition Co-Q10 powder, comprise the following steps：
S1, by beta-schardinger dextrin, Arabic gum, water it is (1.5-2.5) in mass ratio：(8-12)：(85-95) is well mixed,
Obtain mixed liquor A；By Co-Q10 powder be added in olive oil be 35-45 DEG C in temperature at stirred using rotating speed as 150-200 revs/min
Mixing 8-12 minutes is well mixed, and wherein the mass ratio of Co-Q10 powder and olive oil is (0.08-0.12)：1, obtain mixed liquid B；
Mixed liquid B is added using rotating speed as 11000-13000 revs/min of stirring 120-240 second in mixed liquor A, wherein mixed liquid B is with mixing
Liquid A mass ratio is (0.1-0.15)：1, obtain emulsion；Emulsion is spray-dried, obtains microencapsulation Co-Q10
Powder；
S2, by 5-15 parts by weight microencapsulation Co-Q10s powder, 13-17 parts by weight sweet oranges powder, 0.03-0.06 parts by weight protect
Deposit agent, 78-82 parts by weight maltodextrin is well mixed and produced.
As another improved technical scheme, a kind of preparation method of nutrition Co-Q10 powder, comprise the following steps：
S1, by beta-schardinger dextrin, Arabic gum, water it is (1.5-2.5) in mass ratio：(8-12)：(85-95) is well mixed,
Obtain mixed liquor A；By Co-Q10 powder, vitamin E be added in olive oil be 35-45 DEG C in temperature at using rotating speed as 150-200
Rev/min stirring 8-12 minutes be well mixed, wherein the mass ratio of Co-Q10 powder and olive oil is (0.08-0.12)：1, vitamin
The mass ratio of E and olive oil is (0.01-0.003)：1, obtain mixed liquid B；By mixed liquid B add mixed liquor A in using rotating speed as
11000-13000 revs/min of stirring 120-240 second, the wherein mass ratio of mixed liquid B and mixed liquor A is (0.1-0.15)：1, obtain
Emulsion；Emulsion is spray-dried, obtains microencapsulation Co-Q10 powder；
S2, by 5-15 parts by weight microencapsulation Co-Q10s powder, 13-17 parts by weight sweet oranges powder, 0.03-0.06 parts by weight protect
Deposit agent, 78-82 parts by weight maltodextrin is well mixed and produced.
The preservative agent is Cordyceps sinensis polysaccharide and/or grifolan.In the present invention in an embodiment, the preservation
Agent is made up of 55-65wt% Cordyceps sinensis polysaccharides and 35-45wt% grifolans.
The condition of the spray drying is that EAT is 170-190 DEG C, and leaving air temp is 75-85 DEG C, and hot blast wind speed is
3.5-4.5m3/ min, feeding speed 35-45mL/min, atomizer rotating speed are 200-400 revs/min.
A kind of nutrition Co-Q10 powder, is prepared by above-mentioned preparation method.
Technique effect：
The preparation method of nutrition Co-Q10 powder of the present invention, using microcapsules technology, with appropriate wall material to embedding,
By spray drying process to Co-Q10 carry out microencapsulation, can to effectively improve its light, heat and oxidation stability,
And its slow release effect in human body can be realized, effectively improve the bioavilability in human body.The nutrition of the present invention
Co-Q10 powder between each composition by reasonably matching, not only tasty and refreshing, aromatic flavour, and has anti-oxidation health effect.
Embodiment
Nutrition Co-Q10 powder is placed in into temperature to be 25 ± 1 DEG C, be sealed 6 in the environment of relative humidity is 60 ± 5%
Month.
Dissolubility is tested.It is auxiliary that 1g nutrition is weighed using electronic balance (Denver companies of the U.S. provide, model TB-114)
Enzyme Q10 powder, 50 DEG C of water 50ml is added, is stirred with glass bar, the time that metering nutrition Co-Q10 powder all dissolves.
The measure of inoxidizability, using DPPH methods.DPPH accurately is weighed, is configured to 0.2mmol/LDPPH solution, Yu Zong
Color bottle lucifuge Cord blood.Testing sample is diluted to 1.0mg/mL with deionized water.2mL, 1.0mg/mL sample liquid are taken in examination
In pipe, add 2mL, 0.2mmol/LDPPH solution and be well mixed, after lucifuge stands 30min at room temperature, use ultraviolet specrophotometer
UV-2000 (You Nike (Shanghai) limited instrument company) measure 517nm at absorbance, be calculated as Ai, at the same determine 2mL,
1.0mg/mL sample liquids add 2mL absolute ethyl alcohols, (outstanding with ultraviolet specrophotometer UV-2000 after lucifuge stands 30min at room temperature
Ni Ke (Shanghai) limited instrument company) measure absorbance at 517nm, it is calculated as Aj, and 2mL, 0.2mmol/LDPPH solution
Add 2ml distilled water to stand, determined with ultraviolet specrophotometer UV-2000 (You Nike (Shanghai) limited instrument company) in 517nm
Locate absorbance, be calculated as Ac.The clearance rate of DPPH free radicals is calculated as follows sample：Clearance rate=[1- (Ai-Aj)/Ac] ×
100%.
Co-Q10 powder is provided by Zhejiang Medicine Co in embodiment, content 99.6wt%.
Beta-schardinger dextrin is the food-grade beta-schardinger dextrin that Anhui Hong Chang bio tech ltd provides in embodiment.
Arabic gum is the food grade arabinose glue that Jiangsu Fu Shengde bioengineering Co., Ltd provides in embodiment.
Vitamin E is the pharmaceutical grade vitamin E that Shaanxi Sen Fu natural products Co., Ltd provides in embodiment.
Olive oil is the Ou Li common vetch orchid olive oil that Zhejiang benefit Hai Jiali food industry Co., Ltd provides in embodiment.
Sweet orange powder is provided by Shaanxi Sen Fu natural products Co., Ltd in embodiment, and extraction source is sweet orange.
Maltodextrin is the food-grade maltodextrin that Shaanxi Sen Fu natural products Co., Ltd provides in embodiment.
Grifolan in embodiment, provided by Shaanxi Bai Wei bio tech ltd, extraction source is grifola frondosus.
Cordyceps sinensis polysaccharide in embodiment, provided by Xi'an all places bio tech ltd, extraction source is cordyceps mycelia.
Embodiment 1
The preparation method of nutrition Co-Q10 powder, comprises the following steps：
S1, by beta-schardinger dextrin, Arabic gum, water in mass ratio be 2：10：90 is well mixed, obtains mixed liquor A；By coenzyme
Q10 powder, vitamin E are added in olive oil be 40 DEG C in temperature at it is well mixed using rotating speed as 180 revs/min of stirrings 10 minutes,
Wherein the mass ratio of Co-Q10 powder and olive oil is 0.1：1, the mass ratio of vitamin E and olive oil is 0.02：1, mixed
Liquid B；It is 12000 revs/min of stirrings 180 seconds, wherein mixed liquid B and mixed liquor A that mixed liquid B, which is added in mixed liquor A using rotating speed,
Mass ratio is 0.13：1, obtain emulsion；Emulsion is spray-dried, EAT is 180 DEG C, leaving air temp 80
DEG C, hot blast wind speed is 4m3/ min, feeding speed 40mL/min, atomizer rotating speed are 300 revs/min, obtain microencapsulation coenzyme
Q10 powder；
S2, by 10 parts by weight microencapsulation Co-Q10 powder, 15 parts by weight sweet orange powder, 0.04 parts by weight Cordyceps sinensis polysaccharide, 80 weights
Amount part maltodextrin is well mixed to produce nutrition Co-Q10 powder.
Embodiment 2
The preparation method of nutrition Co-Q10 powder, comprises the following steps：
S1, by beta-schardinger dextrin, Arabic gum, water in mass ratio be 2：10：90 is well mixed, obtains mixed liquor A；By coenzyme
Q10 powder is added in olive oil be 40 DEG C in temperature at, wherein coenzyme well mixed using rotating speed as 180 revs/min of stirrings 10 minutes
The mass ratio of Q10 powder and olive oil is 0.1：1, obtain mixed liquid B；Mixed liquid B is added in mixed liquor A using rotating speed as 12000
Rev/min stirring 180 seconds, wherein the mass ratio of mixed liquid B and mixed liquor A be 0.13：1, obtain emulsion；Emulsion is sprayed
Mist is dried, and EAT is 180 DEG C, and leaving air temp is 80 DEG C, and hot blast wind speed is 4m3/ min, feeding speed 40mL/min, mist
Change machine rotating speed is 300 revs/min, obtains microencapsulation Co-Q10 powder；
S2, by 10 parts by weight microencapsulation Co-Q10 powder, 15 parts by weight sweet orange powder, 0.04 parts by weight Cordyceps sinensis polysaccharide, 80 weights
Amount part maltodextrin is well mixed to produce nutrition Co-Q10 powder.
Embodiment 3
The preparation method of nutrition Co-Q10 powder, comprises the following steps：
S1, by 10 parts by weight Co-Q10 powder, 15 parts by weight sweet orange powder, 0.04 parts by weight Cordyceps sinensis polysaccharide, 80 parts by weight malt
Dextrin is well mixed to produce nutrition Co-Q10 powder.
Embodiment 4
The preparation method of nutrition Co-Q10 powder, comprises the following steps：
S1, by beta-schardinger dextrin, Arabic gum, water in mass ratio be 2：10：90 is well mixed, obtains mixed liquor A；By coenzyme
Q10 powder, vitamin E are added in olive oil be 40 DEG C in temperature at it is well mixed using rotating speed as 180 revs/min of stirrings 10 minutes,
Wherein the mass ratio of Co-Q10 powder and olive oil is 0.1：1, the mass ratio of vitamin E and olive oil is 0.02：1, mixed
Liquid B；It is 12000 revs/min of stirrings 180 seconds, wherein mixed liquid B and mixed liquor A that mixed liquid B, which is added in mixed liquor A using rotating speed,
Mass ratio is 0.13：1, obtain emulsion；Emulsion is spray-dried, EAT is 180 DEG C, leaving air temp 80
DEG C, hot blast wind speed is 4m3/ min, feeding speed 40mL/min, atomizer rotating speed are 300 revs/min, obtain microencapsulation coenzyme
Q10 powder；
S2, by 10 parts by weight microencapsulation Co-Q10 powder, 15 parts by weight sweet orange powder, 0.04 parts by weight grifolan, 80
Parts by weight maltodextrin is well mixed to produce nutrition Co-Q10 powder.
Embodiment 5
The preparation method of nutrition Co-Q10 powder, comprises the following steps：
S1, by beta-schardinger dextrin, Arabic gum, water in mass ratio be 2：10：90 is well mixed, obtains mixed liquor A；By coenzyme
Q10 powder, vitamin E are added in olive oil be 40 DEG C in temperature at it is well mixed using rotating speed as 180 revs/min of stirrings 10 minutes,
Wherein the mass ratio of Co-Q10 powder and olive oil is 0.1：1, the mass ratio of vitamin E and olive oil is 0.02：1, mixed
Liquid B；It is 12000 revs/min of stirrings 180 seconds, wherein mixed liquid B and mixed liquor A that mixed liquid B, which is added in mixed liquor A using rotating speed,
Mass ratio is 0.13：1, obtain emulsion；Emulsion is spray-dried, EAT is 180 DEG C, leaving air temp 80
DEG C, hot blast wind speed is 4m3/ min, feeding speed 40mL/min, atomizer rotating speed are 300 revs/min, obtain microencapsulation coenzyme
Q10 powder；
S2, by 10 parts by weight microencapsulation Co-Q10 powder, 15 parts by weight sweet orange powder, 0.016 parts by weight grifolan,
0.024 parts by weight Cordyceps sinensis polysaccharide, 80 parts by weight maltodextrins are well mixed to produce nutrition Co-Q10 powder.
Nutrition Co-Q10 powder is placed in into temperature to be 25 ± 1 DEG C, be sealed 6 in the environment of relative humidity is 60 ± 5%
Month after tested, as a result for：Dissolution time is 41s, and the clearance rate of DPPH free radicals is 73%.
Test case 1
It is 25 ± 1 DEG C, in the environment of relative humidity is 60 ± 5% that embodiment 1-4 nutrition Co-Q10 powder is placed in into temperature
Tested after being sealed 6 months.
Specific test result is shown in Table 1.
Table 1：Test result table
| Dissolution time (s) | The clearance rate (%) of DPPH free radicals | |
| Embodiment 1 | 50 | 69 |
| Embodiment 2 | 56 | 64 |
| Embodiment 3 | 69 | 51 |
| Embodiment 4 | 48 | 67 |
The preparation method of nutrition Co-Q10 powder of the present invention, Co-Q10 powder is transformed into by solid-state instant using microcapsules technology
Powder, make it more stable, Shelf-life, products obtained therefrom dissolubility is good, easy to use, hygienic.Embodiment 1 adds vitamin
E, effect increase substantially；Its reason may is that, ties up E and Co-Q10 is extremely similar, and the compatibility of the two may be more preferable,
Make obtained microencapsulation Co-Q10 powder more stable.
Claims (7)
1. a kind of preparation method of nutrition Co-Q10 powder, it is characterised in that comprise the following steps：
S1, by Co-Q10 powder, sweet orange powder, preservative agent, maltodextrin is well mixed produces.
2. a kind of preparation method of nutrition Co-Q10 powder, it is characterised in that comprise the following steps：
S1, by 5-15 parts by weight Co-Q10s powder, 13-17 parts by weight sweet oranges powder, 0.03-0.06 parts by weight preservative agent, 78-82 weight
Amount part maltodextrin is well mixed to be produced.
3. a kind of preparation method of nutrition Co-Q10 powder, it is characterised in that comprise the following steps：
S1, by beta-schardinger dextrin, Arabic gum, water it is (1.5-2.5) in mass ratio：(8-12)：(85-95) is well mixed, obtains
Mixed liquor A；By Co-Q10 powder be added in olive oil be 35-45 DEG C in temperature at using rotating speed as 150-200 revs/min stirring 8-
12 minutes well mixed, and wherein the mass ratio of Co-Q10 powder and olive oil is (0.08-0.12)：1, obtain mixed liquid B；Will be mixed
Liquid B is closed to add in mixed liquor A using rotating speed as 11000-13000 revs/min of stirring 120-240 second, wherein mixed liquid B and mixed liquor A
Mass ratio be (0.1-0.15)：1, obtain emulsion；Emulsion is spray-dried, obtains microencapsulation Co-Q10 powder；
S2, by 5-15 parts by weight microencapsulation Co-Q10s powder, 13-17 parts by weight sweet oranges powder, 0.03-0.06 parts by weight preservative agent,
78-82 parts by weight maltodextrin is well mixed to be produced.
4. the preparation method of nutrition Co-Q10 powder according to claim 3, it is characterised in that comprise the following steps：
S1, by beta-schardinger dextrin, Arabic gum, water it is (1.5-2.5) in mass ratio：(8-12)：(85-95) is well mixed, obtains
Mixed liquor A；By Co-Q10 powder, vitamin E be added in olive oil be 35-45 DEG C in temperature at by 150-200 of rotating speed turn/
Stirring 8-12 minutes are divided to be well mixed, wherein the mass ratio of Co-Q10 powder and olive oil is (0.08-0.12)：1, vitamin E with
The mass ratio of olive oil is (0.01-0.003)：1, obtain mixed liquid B；By mixed liquid B add mixed liquor A in using rotating speed as
11000-13000 revs/min of stirring 120-240 second, the wherein mass ratio of mixed liquid B and mixed liquor A is (0.1-0.15)：1, obtain
Emulsion；Emulsion is spray-dried, obtains microencapsulation Co-Q10 powder；
S2, by 5-15 parts by weight microencapsulation Co-Q10s powder, 13-17 parts by weight sweet oranges powder, 0.03-0.06 parts by weight preservative agent,
78-82 parts by weight maltodextrin is well mixed to be produced.
5. according to the preparation method of the nutrition Co-Q10 powder of claim 3 or 4, it is characterised in that the preservative agent is cordyceps sinensis
Polysaccharide and/or grifolan.
6. according to the preparation method of the nutrition Co-Q10 powder of claim 3 or 4, it is characterised in that the bar of the spray drying
Part is that EAT is 170-190 DEG C, and leaving air temp is 75-85 DEG C, and hot blast wind speed is 3.5-4.5m3/ min, feeding speed are
35-45mL/min, atomizer rotating speed are 200-400 revs/min.
7. a kind of nutrition Co-Q10 powder, is prepared using preparation method any one of claim 1-6.
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1969833A (en) * | 2005-11-25 | 2007-05-30 | 浙江医药股份有限公司新昌制药厂 | Dry powder composition containing CoQ10 and preparation process thereof |
| US20130309313A1 (en) * | 2012-05-21 | 2013-11-21 | Ocean Nutrition Canada Limited | Compositions and Methods for Increasing the Stability of Food Product Additives |
| CN104323283A (en) * | 2014-11-10 | 2015-02-04 | 厦门金达威集团股份有限公司 | Coenzyme Q10-containing nutritional composition as well as preparation method and application of coenzyme Q10-containing nutritional composition |
| CN105211883A (en) * | 2015-08-24 | 2016-01-06 | 华南理工大学 | A kind of food-grade Co-Q10 microcapsules and its preparation method and application |
| CN106820118A (en) * | 2017-01-17 | 2017-06-13 | 吉速利（上海）健康科技股份有限公司 | Health care Co-Q10 powder and preparation method thereof |
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2017
- 2017-09-29 CN CN201710908786.0A patent/CN107712871A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1969833A (en) * | 2005-11-25 | 2007-05-30 | 浙江医药股份有限公司新昌制药厂 | Dry powder composition containing CoQ10 and preparation process thereof |
| US20130309313A1 (en) * | 2012-05-21 | 2013-11-21 | Ocean Nutrition Canada Limited | Compositions and Methods for Increasing the Stability of Food Product Additives |
| CN104323283A (en) * | 2014-11-10 | 2015-02-04 | 厦门金达威集团股份有限公司 | Coenzyme Q10-containing nutritional composition as well as preparation method and application of coenzyme Q10-containing nutritional composition |
| CN105211883A (en) * | 2015-08-24 | 2016-01-06 | 华南理工大学 | A kind of food-grade Co-Q10 microcapsules and its preparation method and application |
| CN106820118A (en) * | 2017-01-17 | 2017-06-13 | 吉速利（上海）健康科技股份有限公司 | Health care Co-Q10 powder and preparation method thereof |
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