CN107702970A - Hypericin drug content detection device - Google Patents
Hypericin drug content detection device Download PDFInfo
- Publication number
- CN107702970A CN107702970A CN201710900226.0A CN201710900226A CN107702970A CN 107702970 A CN107702970 A CN 107702970A CN 201710900226 A CN201710900226 A CN 201710900226A CN 107702970 A CN107702970 A CN 107702970A
- Authority
- CN
- China
- Prior art keywords
- casing
- welded
- hypericin
- pipe
- detection means
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- BTXNYTINYBABQR-UHFFFAOYSA-N hypericin Chemical compound C12=C(O)C=C(O)C(C(C=3C(O)=CC(C)=C4C=33)=O)=C2C3=C2C3=C4C(C)=CC(O)=C3C(=O)C3=C(O)C=C(O)C1=C32 BTXNYTINYBABQR-UHFFFAOYSA-N 0.000 title claims abstract description 30
- 229940005608 hypericin Drugs 0.000 title claims abstract description 30
- PHOKTTKFQUYZPI-UHFFFAOYSA-N hypericin Natural products Cc1cc(O)c2c3C(=O)C(=Cc4c(O)c5c(O)cc(O)c6c7C(=O)C(=Cc8c(C)c1c2c(c78)c(c34)c56)O)O PHOKTTKFQUYZPI-UHFFFAOYSA-N 0.000 title claims abstract description 30
- SSKVDVBQSWQEGJ-UHFFFAOYSA-N pseudohypericin Natural products C12=C(O)C=C(O)C(C(C=3C(O)=CC(O)=C4C=33)=O)=C2C3=C2C3=C4C(C)=CC(O)=C3C(=O)C3=C(O)C=C(O)C1=C32 SSKVDVBQSWQEGJ-UHFFFAOYSA-N 0.000 title claims abstract description 30
- 239000003814 drug Substances 0.000 title claims abstract description 26
- 238000001514 detection method Methods 0.000 title claims abstract description 17
- 229940079593 drug Drugs 0.000 title abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 41
- 239000007791 liquid phase Substances 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 6
- 238000007789 sealing Methods 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims 1
- 238000003756 stirring Methods 0.000 abstract 2
- 230000005540 biological transmission Effects 0.000 abstract 1
- 235000017309 Hypericum perforatum Nutrition 0.000 description 5
- 244000141009 Hypericum perforatum Species 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 241000196324 Embryophyta Species 0.000 description 2
- 241000546188 Hypericum Species 0.000 description 1
- 240000005342 Hypericum chinense Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/44—Sample treatment involving radiation, e.g. heat
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention discloses a hypericin drug content detection device which comprises a bottom plate, wherein a box body is welded on one side of the top end of the bottom plate, a storage battery is fixed on one side of the bottom end of the box body through bolts, a charging port is formed in the bottom end of the outer wall of the box body, which is close to the storage battery, the bottom end of the outer wall of the box body is provided with heaters which are distributed equidistantly, the top end of each heater is connected with a heat conducting plate, a horizontally placed filter plate is welded on the position, close to the bottom end, of the inner wall of the box body, a motor is welded in the center position of the top end of the box body, a transmission rod is welded at the bottom end of an output shaft of the motor and is positioned in the box body, stirring. The hypericin dissolving device is simple in structure, can fully stir hypericin medicines, regulates and controls the temperature of water during dissolving, promotes the dissolving of hypericin medicines, is high in automation degree, and is time-saving and labor-saving.
Description
Technical field
The present invention relates to hypericin detection technique field, more particularly to a kind of hypericin medicament contg detection means.
Background technology
At present, hypericin is the most material of bioactivity in hypericum perforatum, has antiviral, antidepression and light is dynamic lives
Property.In addition to hypericum perforatum, hypericin is distributed widely in the other plants of Hypericum group and group plant.In recent years, disease-resistant
Malicious (including HIV), the photochemical therapy of cancer, hypericum perforatum antidepression Mechanism Study etc. are very active；Leaf company is passed through in China
It is wide to stick up geographical distribution, applicating history is long, but clinical practice is single for a long time.Research of the China to hypericum perforatum collects more
In on Hypericum Chinense glycoside material, and active very high hypericin and other active components are not yet drawn attention.If it can tie
The theoretical and a large amount of clinical experience of traditional medication is closed, strengthens the exploitation dynamics to active component, therefrom excavates with Chinese characteristics
Each kind new medicine, good social and economic benefit will be produced；Needed after the production of hypericin medicine to wherein hypericin
Concentration detected, but existing detection means effect is not ideal enough, it is impossible to make hypericin sufficiently soluble in water,
Therefore, a kind of hypericin medicament contg detection means is needed badly.
The content of the invention
The invention aims to solve shortcoming present in prior art, and a kind of hypericin medicine proposed contains
Amount detecting device.
To achieve these goals, present invention employs following technical scheme：
A kind of hypericin medicament contg detection means, including bottom plate, the side on the bottom plate top are welded with casing, the case
The side of body bottom has been bolted battery, and casing is provided with charge port close to the side outer wall bottom of battery, institute
State casing bottom and be bolted the heater equidistantly distributed, and the top of heater is connected with same heat-conducting plate,
The cabinet wall is welded with horizontal positioned filter close to bottom position, and the center on the casing top is welded with electricity
Machine, and the bottom of motor output shaft is welded with drive link, the drive link are located at the inside of casing, outside the side of the drive link
The paddle equidistantly distributed is welded with wall, the quantity of the paddle is five to ten five, the side on the casing top
Regulation button is bolted, the side of the casing top away from regulation button is welded with feed pipe, the casing one
Side outer wall is welded with water inlet pipe close to apical position, and the casing is welded with communicating pipe on the side outer wall away from water inlet pipe, institute
State position of the bottom plate top away from casing and be welded with support, the top of the support has been bolted water pump and liquid phase surveys spectrum
Instrument, and the water inlet of water pump is connected with communicating pipe, water pipe is welded with the inwall of the delivery port of the water pump, and water pipe is another
End is surveyed spectrometer with liquid phase and is connected.
Preferably, the bottom of the bottom plate has been bolted four universal wheels, and four universal wheels are located at bottom respectively
Four corners of plate.
Preferably, the heat-conducting plate lies in a horizontal plane in the inside of casing, and inwall of the edge of heat-conducting plate with casing
It is connected, heat-conducting plate is made up of albronze material.
Preferably, the casing is provided with mounting hole on the side inwall of battery, and temperature is plugged with mounting hole
Sensor, and temperature sensor is bonded with sealing gasket with casing junction, temperature sensor is between filter and heat-conducting plate.
Preferably, the feed pipe, water inlet pipe and valve is equipped with communicating pipe, and the diameter of feed pipe is more than communicating pipe
Diameter.
Preferably, the heater, motor, water pump and temperature sensor are respectively connected with controller, and the model of controller
For DATA-7311.
Beneficial effects of the present invention are：The device structure is simple, can be sufficiently right by the setting of motor and paddle
Hypericin medicine is stirred, and promotes its dissolving, and the setting of water inlet pipe and feed pipe can add medicine at any time in dissolving
Raw material, the time is saved, and improve dissolved efficiency, the temperature of water when can regulate and control dissolving by the setting of heater and heat-conducting plate
Degree, promotes its dissolving, and water pump can be drawn into the hypericin medicine after abundant dissolving in liquid chromatograph and detect it and contain
Amount, automaticity is high, time saving and energy saving.
Brief description of the drawings
Fig. 1 is a kind of cross-sectional view of hypericin medicament contg detection means proposed by the present invention；
Fig. 2 is a kind of structural representation of hypericin medicament contg detection means paddle proposed by the present invention.
In figure：1 bottom plate, 2 casings, 3 batteries, 4 heat-conducting plates, 5 heaters, 6 supports, 7 liquid chromatographs, 8 water pumps, 9 connect
Siphunculus, 10 paddles, 11 motors, 12 feed pipes, 13 water inlet pipes, 14 filters, 15 temperature sensors.
Embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete
Site preparation describes, it is clear that described embodiment is only part of the embodiment of the present invention, rather than whole embodiments.
Reference picture 1-2, a kind of hypericin medicament contg detection means, including bottom plate 1, the side welding on the top of bottom plate 1
There is casing 2, the side of the bottom of casing 2 has been bolted battery 3, and casing 2 is close to the side outer wall bottom of battery 3
Charge port is provided with, the bottom of casing 2 is bolted the heater 5 equidistantly distributed, and the top of heater 5 is connected with together
One heat-conducting plate 4, the inwall of casing 2 are welded with horizontal positioned filter 14, the center on the top of casing 2 close to bottom position
Motor 11 is welded with, and the bottom of the output shaft of motor 11 is welded with drive link, drive link is located at the inside of casing 2, drive link
It is welded with the paddle 10 equidistantly distributed on the outer wall of side, the quantity of paddle 10 is five to ten five, the one of the top of casing 2
Side has been bolted regulation button, and side of the top of casing 2 away from regulation button is welded with feed pipe 12, the side of casing 2
Outer wall is welded with water inlet pipe 13 close to apical position, and casing 2 is welded with communicating pipe 9, bottom on the side outer wall away from water inlet pipe 13
Position of the top of plate 1 away from casing 2 is welded with support 6, and the top of support 6 has been bolted water pump 8 and liquid phase surveys spectrometer
7, and the water inlet of water pump 8 is connected with communicating pipe 9, and water pipe, and the other end of water pipe are welded with the inwall of the delivery port of water pump 8
Spectrometer 7 is surveyed with liquid phase to be connected.
In the present invention, the bottom of bottom plate 1 has been bolted four universal wheels, and four universal wheels are located at bottom plate respectively
1 four corners, heat-conducting plate 4 lie in a horizontal plane in the inside of casing 2, and inwall phase of the edge of heat-conducting plate 4 with casing 2
Connection, heat-conducting plate 4 are made up of albronze material, and casing 2 is provided with mounting hole on the side inwall of battery 3, and installs
Temperature sensor 15 is plugged with hole, and temperature sensor 15 is bonded with sealing gasket, temperature sensor 15 with the junction of casing 2
Between filter 14 and heat-conducting plate 4, feed pipe 12, water inlet pipe 13 and valve is equipped with communicating pipe 9, and feed pipe 12 is straight
Footpath is more than the diameter of communicating pipe 9, and heater 5, motor 11, water pump 8 and temperature sensor 15 are respectively connected with controller, and controller
Model DATA-7311.
Operation principle：In use, adding medicine material and water by water inlet pipe 13 and feed pipe 12, then start motor 11
Drive paddle 10 to be stirred hypericin medicine, promote its dissolving, while regulation button, heater 5 and heat-conducting plate 4 are adjusted
The temperature of water is controlled, promotes its dissolving, the hypericin pharmaceutical liquid of dissolving is drawn into by water pump 9 by liquid chromatograph after dissolving
Its content is detected in 7.
The foregoing is only a preferred embodiment of the present invention, but protection scope of the present invention be not limited thereto,
Any one skilled in the art the invention discloses technical scope in, technique according to the invention scheme and its
Inventive concept is subject to equivalent substitution or change, should all be included within the scope of the present invention.
Claims (6)
1. a kind of hypericin medicament contg detection means, including bottom plate（1）, it is characterised in that the bottom plate（1）The one of top
Side is welded with casing（2）, the casing（2）The side of bottom has been bolted battery（3）, and casing（2）Close to storage
Battery（3）Side outer wall bottom be provided with charge port, the casing（2）Bottom is bolted the heating equidistantly distributed
Device（5）, and heater（5）Top be connected with same heat-conducting plate（4）, the casing（2）Inwall welds close to bottom position
There is horizontal positioned filter（14）, the casing（2）The center on top is welded with motor（11）, and motor（11）Output
The bottom of axle is welded with drive link, and the drive link is located at casing（2）Inside, be welded with the side outer wall of the drive link
The paddle equidistantly distributed（10）, the paddle（10）Quantity be five to ten five, the casing（2）The side on top
It has been bolted regulation button, the casing（2）Side of the top away from regulation button is welded with feed pipe（12）, it is described
Casing（2）Side outer wall is welded with water inlet pipe close to apical position（13）, the casing（2）Away from water inlet pipe（13）Side outside
Communicating pipe is welded with wall（9）, the bottom plate（1）Top is away from casing（2）Position be welded with support（6）, the support（6）
Top be bolted water pump（8）Spectrometer is surveyed with liquid phase（7）, and water pump（8）Water inlet and communicating pipe（9）It is connected,
The water pump（8）Delivery port inwall on be welded with water pipe, and the other end of water pipe surveys spectrometer with liquid phase（7）It is connected.
A kind of 2. hypericin medicament contg detection means according to claim 1, it is characterised in that the bottom plate（1）
Bottom be bolted four universal wheels, and four universal wheels are located at bottom plate respectively（1）Four corners.
A kind of 3. hypericin medicament contg detection means according to claim 1, it is characterised in that the heat-conducting plate
（4）Lie in a horizontal plane in casing（2）Inside, and heat-conducting plate（4）Edge and casing（2）Inwall be connected, heat-conducting plate
（4）It is made up of albronze material.
A kind of 4. hypericin medicament contg detection means according to claim 1, it is characterised in that the casing（2）
Close to battery（3）Side inwall on be provided with mounting hole, and temperature sensor is plugged with mounting hole（15）, and TEMP
Device（15）With casing（2）Junction is bonded with sealing gasket, temperature sensor（15）Positioned at filter（14）And heat-conducting plate（4）It
Between.
A kind of 5. hypericin medicament contg detection means according to claim 1, it is characterised in that the feed pipe
（12）, water inlet pipe（13）And communicating pipe（9）On be equipped with valve, and feed pipe（12）Diameter be more than communicating pipe（9）Diameter.
A kind of 6. hypericin medicament contg detection means according to claim 1, it is characterised in that the heater
（5）, motor（11）, water pump（8）And temperature sensor（15）It is respectively connected with controller, and the model DATA-7311 of controller.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710900226.0A CN107702970A (en) | 2017-09-28 | 2017-09-28 | Hypericin drug content detection device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710900226.0A CN107702970A (en) | 2017-09-28 | 2017-09-28 | Hypericin drug content detection device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107702970A true CN107702970A (en) | 2018-02-16 |
Family
ID=61174620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710900226.0A Withdrawn CN107702970A (en) | 2017-09-28 | 2017-09-28 | Hypericin drug content detection device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107702970A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109459394A (en) * | 2018-12-10 | 2019-03-12 | 刘楠 | A kind of food colour chemical detection devices and its detection method |
| CN110554158A (en) * | 2019-08-28 | 2019-12-10 | 齐鲁理工学院 | Traditional chinese medicine chemistry verifying attachment with safeguard function |
-
2017
- 2017-09-28 CN CN201710900226.0A patent/CN107702970A/en not_active Withdrawn
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109459394A (en) * | 2018-12-10 | 2019-03-12 | 刘楠 | A kind of food colour chemical detection devices and its detection method |
| CN109459394B (en) * | 2018-12-10 | 2021-03-12 | 刘楠 | Food pigment chemical detection device and detection method thereof |
| CN110554158A (en) * | 2019-08-28 | 2019-12-10 | 齐鲁理工学院 | Traditional chinese medicine chemistry verifying attachment with safeguard function |
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| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20180216 |