CN107670924A - A kind of fluid bed side-spraying device - Google Patents
A kind of fluid bed side-spraying device Download PDFInfo
- Publication number
- CN107670924A CN107670924A CN201711082340.3A CN201711082340A CN107670924A CN 107670924 A CN107670924 A CN 107670924A CN 201711082340 A CN201711082340 A CN 201711082340A CN 107670924 A CN107670924 A CN 107670924A
- Authority
- CN
- China
- Prior art keywords
- fluid bed
- side spray
- pedestal
- distribution plate
- cavity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C19/00—Apparatus specially adapted for applying particulate materials to surfaces
- B05C19/02—Apparatus specially adapted for applying particulate materials to surfaces using fluidised-bed techniques
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/005—Coating of tablets or the like
Abstract
The invention discloses a kind of fluid bed side-spraying device, including fluid bed body with middle cavity, level are installed in the intrinsic air distribution plate of the fluid bed, and pharmacy particle is placed with the fluid bed body above air distribution plate；The side spray pedestal of cavity in band is installed with fluid bed this body sidewall above air distribution plate outer, the middle cavity of side spray pedestal is mutually communicated with the middle cavity of fluid bed body；The side spray spray gun penetrated outside it to wherein in cavity is coaxially provided with side spray pedestal；The axially external nozzle guard gas airduct being provided with the insertion of wherein cavity of side spray pedestal, protection gas air-flow enters to fluid bed body by nozzle guard gas airduct via side spray pedestal reduces the investment of client；Meanwhile can not shut down clear rifle online, avoid because nozzle be blocked need to carry out shutting down clear rifle operation and to client caused by loss.With the function of being pelletized and be coated simultaneously, operation replacing is particularly convenient, effectively.
Description
Technical field
The invention belongs to solid pharmaceutical preparation production technical field, is related to a kind of fluid bed of granulation and coating, specifically,
It is related to a kind of fluid bed side-spraying device.
Background technology
Solid pharmaceutical preparation granulation at present and coating device, mainly using bottom spray and top spray structure.
Bottom spray is mainly used in being coated, and top spray is used to pelletize.Due to pelletize and be coated need to use different structure spray gun, it is necessary to
Continually carry out replacement operation.
Meanwhile bottom spray coating structure, spray gun are fixed together with distribution grid, dismounting inconvenience, once nozzle is by solid pharmaceutical
Particle is blocked, it is necessary to could carry out removing clear rifle operation after equipment downtime, not only troublesome in poeration, and also can not after starting shooting again
The coating effect of solid pharmaceutical particle is consistent twice before and after ensureing.Therefore the unstable technology for bringing product quality again is asked
Topic.
The content of the invention
The purpose of the present invention is overcome the deficiencies in the prior art or defect, there is provided a kind of fluid bed side-spraying device, is had same
Shi Jinhang pelletizes and the function of coating, and particularly convenient, effective investment for reducing client is changed in operation；Simultaneously, it is possible to achieve do not stop
The clear rifle function of machine, avoid because nozzle be blocked need to carry out shutting down clear rifle operation and to client caused by loss.
To achieve these goals, present invention employs following technical scheme：
A kind of fluid bed side-spraying device, including the fluid bed body with middle cavity, level are installed in the fluid bed sheet
Internal air distribution plate, pharmacy particle is placed with the fluid bed body above the air distribution plate；Characterized in that,
The side spray pedestal of cavity in band is installed with fluid bed this body sidewall above the air distribution plate outer, it is described
The middle cavity of the middle cavity of side spray pedestal and the fluid bed body is mutually communicated；
The side spray spray gun penetrated outside it to wherein in cavity is coaxially provided with the side spray pedestal；
The axially external nozzle guard gas airduct being provided with the insertion of wherein cavity of the side spray pedestal, protection gas air-flow lead to
Cross the hollow intracavitary that the nozzle guard gas airduct enters to the fluid bed body via the side spray pedestal.
Above-mentioned fluid bed side-spraying device, wherein,
The protection gas air-flow of the nozzle guard gas airduct introduces from the lower section of airflow-distribution board, the nozzle guard gas wind
The entrance of pipe connects with the fluid bed body lower part below the air distribution plate.
The protection gas air-flow of the nozzle guard gas airduct introduces from the outside of the fluid bed, the nozzle guard gas wind
Pipe disconnects with the fluid bed body lower part below the air distribution plate.
The longitudinal direction of cavity is inner in the side spray pedestal is provided with taper throat structure.
Appropriate spacing is left between the inner face of the nozzle of the side spray spray gun and the side spray pedestal.
The quick fixation structure part with clip and sealing ring is used to be tightly connected between the side spray spray gun and side spray pedestal.
The nozzle of the side spray spray gun is two-fluid spray nozzle, is respectively used to fluidized bed granulation and coating.
The air distribution plate is eddy flow distribution grid, and the protection gas air-flow of the nozzle guard gas airduct passes through distribution of air flow
It is in eddy flow shape flow regime after plate, pharmacy particle is got rid of into the inwall surrounding to the fluid bed body.
Compared with prior art, the invention has the advantages that：
With the function of being pelletized and be coated simultaneously, particularly convenient, the effectively investment of reduction client is changed in operation；Together
When, it is possible to achieve do not shut down clear rifle function, avoid because nozzle be blocked need to carry out shutting down clear rifle operation and to client caused by damage
Lose.
Brief description of the drawings
Fig. 1 is the structural representation of the fluid bed side-spraying device of the present invention that nozzle guard gas is introduced below distribution grid
Figure；
Fig. 2 is the fluid bed side-spraying device structural representation of the present invention for being introduced from outside into nozzle guard gas.
Embodiment
With reference to the figures above, technical scheme and beneficial effect are further described and illustrated.
Fig. 1,2 are referred to, a kind of fluid bed side-spraying device of the present invention is shown in figure, its key technology scheme exists
In：
The fluid bed side-spraying device, including the fluid bed body 7 with middle cavity 7a, level are installed in the fluid bed sheet
Air distribution plate 1 in body 7, in the fluid bed body 7d of the top of air distribution plate 1 cavity 7a in be placed with pharmacy particle 8.
The side spray pedestal 3 of cavity 3a in band, side are installed with the side wall of fluid bed body 7 above the outer of air distribution plate 1
The middle cavity 7a for spraying the middle cavity 3a and the fluid bed body 7 of pedestal 3 is mutually communicated；
The side spray spray gun 6 penetrated outside it to wherein in cavity 3a is coaxially provided with side spray pedestal 3；
The axially external nozzle guard gas airduct 2 being provided with wherein cavity 3a insertions of side spray pedestal 3, protection gas air-flow lead to
Nozzle guard gas airduct 2 is crossed to enter in the middle cavity 7a of fluid bed body 7 via side spray pedestal 3.
Embodiment 1, the protection gas air-flow of nozzle guard gas airduct 2 introduce from the lower section of airflow-distribution board 1, nozzle guard gas
Airduct 2 connects with the bottom of the fluid bed body 7 of the lower section of air distribution plate 1.
Embodiment 2, the protection gas air-flow of nozzle guard gas airduct 2 introduce from the outside of fluid bed body 7, nozzle guard gas
The bottom of airduct 2 and the fluid bed body 7 of the lower section of air distribution plate 1 disconnects.
The longitudinal direction of the middle cavity of side spray pedestal 3 is inner to be provided with taper throat structure.The nozzle of side spray spray gun 6 and side spray pedestal
Appropriate spacing is left between 3 inner face.Used between side spray spray gun 6 and side spray pedestal 3 fast with clip 5 and sealing ring 4
Assembling structure part is tightly connected.
As shown in figure 1, air distribution plate 1 is arranged in fluid bed body 7.Air distribution plate is eddy flow distribution grid, nozzle
The protection gas air-flow of protection gas airduct 2 is in eddy flow shape flow regime after passing through air distribution plate 1, and pharmacy particle 8 is got rid of to fluidisation
The inwall surrounding of bed body 7.Air distribution plate 1 makes air-flow form eddy flow, and the protection gas air-flow of nozzle guard gas airduct 2 drives system
The spiral of medicine particle 8 is moved, significantly lifting granulation and coating speed.
As shown in figure 1, side spray pedestal 3 is welded on the fluid bed body 7 of the top of air distribution plate 1, nozzle guard gas wind
The fluid bed barrel soldering of the one end of pipe 2 and the lower section of air distribution plate 1, the other end weld with side spray pedestal 3.
As shown in figure 1, side spray pedestal 3 is fixed together with side spray spray gun 6 by fast card mode, sealing ring 4 is used for side spray
Sealing between pedestal 3 and side spray spray gun 6, clip 5 are used for being fixedly clamped between side spray pedestal 3 and side spray spray gun 6.
The nozzle of side spray spray gun 6 is two-fluid spray nozzle, and a kind of fluid is liquid, and one other fluid is gas；It is respectively used to
Fluidized bed granulation and coating.
The side-spraying device protects gas all the way by drawing from distribution grid lower section or outside.The protection gas is used to blow away close to spray
The pharmacy particle 8 of mouth, prevents spray gun from being blocked by pharmacy particle 8.Certain distance between nozzle and pharmacy particle 8 is given simultaneously, can
So that the liquid that the nozzle of side spray spray gun 6 sprays contacts with pharmacy particle 8 again after being fully atomized, lifting granulation and coating effect.
Side spray spray gun 6 is scaled in pedestal, and is maintained a certain distance with base end inner face, reduces nozzle and pharmacy particle
8 contact, avoids spray nozzle clogging.
The end of side spray pedestal 3 uses necking form, reduces airflow area to increase the velocity of liquid assets of nozzle guard gas,
The effect of air-flow protection nozzle is lifted, prevents spray nozzle clogging.
Below in conjunction with the substantially course of work for illustrating the side-spraying device：
Fluid bed starts, and air-flow moves upwards from the lower section of airflow-distribution board 1.Air-flow becomes after through airflow-distribution board 1
Eddy flow state, air-flow drive the helically motion upwards of pharmacy particle 8.From the lower section of airflow-distribution board 1, as shown in figure 1, or such as
Shown in Fig. 2, draw from outside and protect gas to enter in 3 laggard fluidized bed of side spray pedestal all the way.Side spray spray gun 6 contracts in side spray pedestal 3
It is interior, and there is protection gas to be used to protect nozzle, prevent its blocking.
The solid pharmaceutical particle 8 of screw is just opened by protection air-blowing when close to side spray pedestal 3, makes solid pharmaceutical
The nozzle of grain 8 and side spray spray gun maintains a certain distance.The liquid that the nozzle of side spray spray gun sprays passes through after being fully atomized and solid
System medicine particle 8 contacts, so as to realize granulation or coating.
Air distribution plate 1 of the present invention is eddy flow distribution grid, and air-flow is by being in that eddy flow shape flows after air distribution plate 1
State, pharmacy particle 8 is got rid of into the inwall surrounding to fluid bed body 7, effectively reduces the distance between pharmacy particle 8 and spray gun,
Increase coating and granulating efficiency.
It should be further stated that a fluid unit can be equipped with one or more sets side spray dresses of the present invention
Put, suitable for different size and the equipment of yield, there is good versatility.
Above example is used for illustrative purposes only, rather than limitation of the present invention, the technology people about technical field
Member, without departing from the spirit and scope of the present invention, can also make various conversion or modification, therefore all equivalent
Technical scheme should also belong to scope of the invention, should be limited by each claim.
Claims (8)
1. a kind of fluid bed side-spraying device, including the fluid bed body with middle cavity, level are installed in the fluid bed body
Interior air distribution plate, pharmacy particle is placed with the fluid bed body above the air distribution plate；Characterized in that,
The side spray pedestal of cavity in band, the side spray are installed with fluid bed this body sidewall above the air distribution plate outer
The middle cavity of the middle cavity of pedestal and the fluid bed body is mutually communicated；
The side spray spray gun penetrated outside it to wherein in cavity is coaxially provided with the side spray pedestal；
The axially external nozzle guard gas airduct being provided with the insertion of wherein cavity of the side spray pedestal, protection gas air-flow pass through institute
State the hollow intracavitary that nozzle guard gas airduct enters to the fluid bed body via the side spray pedestal.
2. fluid bed side-spraying device according to claim 1, it is characterised in that the protection gas gas of the nozzle guard gas airduct
Flow and introduced from the lower section of airflow-distribution board, entrance and the fluid bed below the air distribution plate of the nozzle guard gas airduct
Body lower part connects.
3. fluid bed side-spraying device according to claim 1, it is characterised in that the protection gas gas of the nozzle guard gas airduct
Flow and introduced from the outside of the fluid bed, under the fluid bed body below the nozzle guard gas airduct and the air distribution plate
Portion disconnects.
4. according to the 1 or 2 or 3 fluid bed side-spraying device of claim, it is characterised in that cavity is vertical in the side spray pedestal
Inboard end is provided with taper throat structure.
5. fluid bed side-spraying device according to claim 4, it is characterised in that the nozzle of the side spray spray gun and the side spray
Appropriate spacing is left between the inner face of pedestal.
6. fluid bed side-spraying device according to claim 5, it is characterised in that adopted between the side spray spray gun and side spray pedestal
It is tightly connected with the quick fixation structure part with clip and sealing ring.
7. fluid bed side-spraying device according to claim 6, it is characterised in that the nozzle of the side spray spray gun sprays for two-fluid
Mouth, it is respectively used to fluidized bed granulation and coating.
8. fluid bed side-spraying device according to claim 7, it is characterised in that the air distribution plate is eddy flow distribution grid,
The protection gas air-flow of the nozzle guard gas airduct is in eddy flow shape flow regime after passing through air distribution plate, by the pharmacy particle
Get rid of the inwall surrounding to the fluid bed body.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711082340.3A CN107670924A (en) | 2017-11-07 | 2017-11-07 | A kind of fluid bed side-spraying device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711082340.3A CN107670924A (en) | 2017-11-07 | 2017-11-07 | A kind of fluid bed side-spraying device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107670924A true CN107670924A (en) | 2018-02-09 |
Family
ID=61146452
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711082340.3A Pending CN107670924A (en) | 2017-11-07 | 2017-11-07 | A kind of fluid bed side-spraying device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107670924A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109537069A (en) * | 2018-11-28 | 2019-03-29 | 江苏丝丝缘纤维有限公司 | A kind of chemical fibre spinneret on-line cleaning method |
| CN112618363A (en) * | 2020-12-16 | 2021-04-09 | 杭州康力生物科技有限公司 | VC fluidized bed bottom spraying coating machine and production method of coated VC |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2406722Y (en) * | 2000-01-22 | 2000-11-22 | 邹龙贵 | Pill making and packing machine |
| JP2005313089A (en) * | 2004-04-28 | 2005-11-10 | Freunt Ind Co Ltd | Particulate treatment apparatus |
| US20100126413A1 (en) * | 2007-07-06 | 2010-05-27 | Jurg Paul Ris | Fluid bed apparatus for coating solid particles |
| CN207430636U (en) * | 2017-11-07 | 2018-06-01 | 上海涵欧制药设备有限公司 | A kind of fluid bed side-spraying device |
-
2017
- 2017-11-07 CN CN201711082340.3A patent/CN107670924A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2406722Y (en) * | 2000-01-22 | 2000-11-22 | 邹龙贵 | Pill making and packing machine |
| JP2005313089A (en) * | 2004-04-28 | 2005-11-10 | Freunt Ind Co Ltd | Particulate treatment apparatus |
| US20100126413A1 (en) * | 2007-07-06 | 2010-05-27 | Jurg Paul Ris | Fluid bed apparatus for coating solid particles |
| CN207430636U (en) * | 2017-11-07 | 2018-06-01 | 上海涵欧制药设备有限公司 | A kind of fluid bed side-spraying device |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109537069A (en) * | 2018-11-28 | 2019-03-29 | 江苏丝丝缘纤维有限公司 | A kind of chemical fibre spinneret on-line cleaning method |
| CN112618363A (en) * | 2020-12-16 | 2021-04-09 | 杭州康力生物科技有限公司 | VC fluidized bed bottom spraying coating machine and production method of coated VC |
| CN112618363B (en) * | 2020-12-16 | 2022-06-14 | 杭州康力生物科技有限公司 | VC fluidized bed bottom spraying coating machine and production method of coated VC |
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