CN107668327A - A kind of application of Quercetin metallo-chelate in animal feed additive - Google Patents
A kind of application of Quercetin metallo-chelate in animal feed additive Download PDFInfo
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- CN107668327A CN107668327A CN201711048711.6A CN201711048711A CN107668327A CN 107668327 A CN107668327 A CN 107668327A CN 201711048711 A CN201711048711 A CN 201711048711A CN 107668327 A CN107668327 A CN 107668327A
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- quercetin
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- chelate
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/111—Aromatic compounds
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Abstract
The present invention relates to animal feed preparing technical field, more particularly to a kind of Quercetin metallo-chelate, in the application of animal feed additive, described Quercetin metallo-chelate is a kind of organic acid metal chela (poly-, network) compound that Quercetin or mixture, crude extract, extract, concentrate containing Quercetin chelate with metal (copper or iron or ferrous iron or zinc or manganese or selenium or chromium or molybdenum or nickel or europium or germanium or cobalt or vanadium or strontium or rubidium or boron or lanthanum or zirconium) salt compound or polymerize or be complexed and formed.The present invention adds Quercetin metallo-chelate in animal feed, to the growing of animal, treat animal diarrhea and has and act on well, without any side effects, using simple.
Description
Technical field
The present invention relates to animal feed preparing technical field, more particularly to a kind of Quercetin metallo-chelate is in animal feed
The application of additive.
Background technology
Animal diarrhea, especially mammiferous economic animal (such as raising pig, fowl, ruminant, aquatic livestock, experiment
Animal and special economic animal etc.) diarrhoea, it is a kind of common disease, frequently-occurring disease, epidemic disease, is the difficulty of a long-standing problem raiser
Topic.Mammal has substantial amounts of mammal because causing by various stress, suffer from diarrhoea every year because anti-stress ability is poor
Subtract food, thin and weak, growth retardation, or even death, very big economic loss is caused to raiser, for veterinarian and one
Very stubborn problem.Quercetin metallo-chelate is Quercetin or its salt compound and complexing of metal ion and one kind for being formed
Organic chelate, the effect of combining Quercetin and metal ion, there is good resisting stress, anti-oxidant, anti-inflammatory, antibacterial to make
With, and small toxicity, it is safe.
The content of the invention
The invention aims to overcome the deficiencies in the prior art, there is provided a kind of Quercetin metal chelating (poly-) compound exists
The application of animal feed additive.
The present invention is to be achieved through the following technical solutions：
For a kind of Quercetin metallo-chelate in the application of animal feed additive, described Quercetin metallo-chelate is Mongolian oak
Skin element or the mixture containing Quercetin, crude extract, extract, concentrate and metal (copper or iron or ferrous iron or zinc or manganese or selenium or
Chromium or molybdenum or nickel or europium or germanium or cobalt or vanadium or strontium or rubidium or boron or lanthanum or zirconium) salt compound chelating polymerization or complexing and formed
A kind of organic acid metal network (chela) compound.
Further, described Quercetin chemical name is 3,3', 4', 5, and 7- pentahydroxyflavones (C15H10O7), it is chemical
Structural formula is as follows：
Further, described metal (copper or iron or ferrous iron or zinc or manganese or selenium or chromium or molybdenum or nickel or europium or germanium or cobalt
Or vanadium or strontium or rubidium or boron or lanthanum or zirconium) salt compound uses any glycinate, methionine salt, the lysine of the metal
Salt, threonine salt, isoleucine salt, leucine salt, glutamate, cystine salt, glutamy amine salt, protein salt, compounded amino
Hydrochlorate, lactate, citrate, fumarate, formates, acetate, butyrate, propionate, sulfate, saline oxide, hydrogen-oxygen
Salt dissolving, chlorate, alkali formula chlorate or other soluble-salt compounds or other insoluble salt compounds.
Further, described Quercetin metallo-chelate includes：Quercetin-Cu, Quercetin ferrous iron, quercitrin plain sheet, quercitrin
Plain zinc, Quercetin manganese, Quercetin selenium, Quercetin chromium, Quercetin molybdenum, Quercetin nickel, Quercetin europium, Quercetin germanium, Quercetin cobalt,
Quercetin vanadium, Quercetin strontium, Quercetin rubidium, Quercetin boron, Quercetin lanthanum, Quercetin zirconium.
Further, described additive capacity is to be added in every kilogram of feed or mixture (with Quercetin metal chelating (poly-)
Compound meter) 0.1-450000mg.
Further, described Quercetin metallo-chelate is directly appended in feed, or former with other feed addictives
It is (with Quercetin metal chelating that material, feedstuff or carrier, which are fabricated to containing such Quercetin metal chelating (poly-) polymer weight content,
(poly-) compound meter) 0.001-99.9% raw material, be then added in animal feed.
Further, the additive is preparing raising pig, fowl, ruminant, aquatic livestock, experimental animal and extraordinary economy
Applied in the feed of animal.
Compared with prior art, the beneficial effects of the invention are as follows：The present invention adds Quercetin metal in animal feed
Chelate, to the growing of animal, treat animal diarrhea there is effect well, it is without any side effects, using simple.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to
Limit the present invention.
Embodiment one：
A kind of Quercetin metallo-chelate is in the application of animal feed additive, the pre-mixing agent containing Quercetin-Cu 5%.Choosing
With body weight about 6.5kg [Du × (big × long)] healthy weanling pig 180,2 groups (control group and test group) are randomly divided into,
Every group of 6 repetitions, often repeatedly 15 (male and female half and half), control group fed Basic drawing, test group are added in Basic drawing
20mg/kg Quercetin-Cus, during experiment, piglet free choice feeding and drinking-water, other feeding managements are according to conventinal breeding rule of management
Carry out.Result of the test shows that for test group compared with control group, the daily gain of piglet improves 7.2% (P<0.05), feed-weight ratio drops
Low 5.7% (P<0.05), grice diarrhoea incidence reduces 61.8% (P<0.05), illustrate that this additive is given birth to weanling pig
Production performance has facilitation.
Embodiment two：
A kind of Quercetin metallo-chelate is in the application of animal feed additive, the pre-mixing agent containing Quercetin zinc 6%.Choosing
With body weight about 10.5kg [Du × (big × long)] healthy weanling pig 120,2 groups (control group and experiments are randomly divided into
Group), every group of 6 repetitions, often repeatedly 10 (male and female half and half), control group fed Basic drawing, test group add in Basic drawing
Add 60mg/kg Quercetin zinc, during experiment, piglet free choice feeding and drinking-water, other feeding managements are advised according to conventinal breeding management
Cheng Jinhang.Result of the test shows that for test group compared with control group, the daily gain of piglet improves 6.7% (P<0.05), feed-weight ratio
Reduce 4.4% (P<0.05), grice diarrhoea incidence reduces 53.7% (P<0.05).
Embodiment three：
A kind of Quercetin metallo-chelate is in the application of animal feed additive, the pre-mixing agent containing Quercetin ferrous iron 7%.
From body weight about 28kg [Du × (big × long)] healthy weanling pig 100,2 groups (control group and experiments are randomly divided into
Group), every group of 5 repetitions, often repeatedly 10 (male and female half and half), control group fed Basic drawing, test group add in Basic drawing
Add 80mg/kg Quercetins ferrous, during experiment, piglet free choice feeding and drinking-water, other feeding managements are according to conventinal breeding management
Code is carried out.Result of the test shows that for test group compared with control group, the daily gain of piglet improves 5.9% (P<0.05), material weight
Than reducing 3.8% (P<0.05), grice diarrhoea incidence reduces 30.5% (P<0.05).
The feed addictive through present inventor for many years repeatedly raising experiment, test, adjust raw material each component ratio,
Achieve effect of the present invention.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
All any modification, equivalent and improvement made within refreshing and principle etc., should be included in the scope of the protection.
Claims (7)
1. a kind of Quercetin metallo-chelate is in the application of animal feed additive, it is characterised in that described Quercetin metal
Chelate is Quercetin or mixture containing Quercetin, crude extract, extract, concentrate and metal (copper or iron or ferrous iron or zinc
Or manganese or selenium or chromium or molybdenum or nickel or europium or germanium or cobalt or vanadium or strontium or rubidium or boron or lanthanum or zirconium) salt compound chelating or polymerization or
A kind of organic acid metal chela (the poly-, network) compound for being complexed and being formed.
2. a kind of Quercetin metallo-chelate according to claim 1 exists in the application of animal feed additive, its feature
It is 3,3', 4', 5 in, described Quercetin chemical name, 7- pentahydroxyflavones (C15H10O7), its chemical structural formula is as follows：
。
3. a kind of Quercetin metallo-chelate according to claim 1 exists in the application of animal feed additive, its feature
In, described metal (copper or iron or ferrous iron or zinc or manganese or selenium or chromium or molybdenum or nickel or europium or germanium or cobalt or vanadium or strontium or rubidium or
Boron or lanthanum or zirconium) salt compound is using any glycinate of the metal, methionine salt, lysine salt, threonine salt, different bright
Propylhomoserin salt, leucine salt, glutamate, cystine salt, glutamy amine salt, protein salt, compound amino acid salt, lactate, lemon
Hydrochlorate, fumarate, formates, acetate, butyrate, propionate, sulfate, saline oxide, hydrogen-oxygen salt dissolving, chlorate, alkali formula
Chlorate or other soluble-salt compounds or other insoluble salt compounds.
4. a kind of Quercetin metallo-chelate according to claim 1 exists in the application of animal feed additive, its feature
In described Quercetin metallo-chelate includes：Quercetin-Cu, Quercetin ferrous iron, quercitrin plain sheet, Quercetin zinc, Quercetin manganese,
Quercetin selenium, Quercetin chromium, Quercetin molybdenum, Quercetin nickel, Quercetin europium, Quercetin germanium, Quercetin cobalt, Quercetin vanadium, quercitrin
Plain strontium, Quercetin rubidium, Quercetin boron, Quercetin lanthanum, Quercetin zirconium.
5. a kind of Quercetin metallo-chelate according to claim 1 exists in the application of animal feed additive, its feature
In described additive capacity is addition 0.1- (in terms of Quercetin metal chelating (poly-) compound) in every kilogram of feed or mixture
450000mg。
6. a kind of Quercetin metallo-chelate according to claim 1 exists in the application of animal feed additive, its feature
In, described Quercetin metallo-chelate is directly appended in feed, or with other raw materials of feed additives, feedstuff or load
It is (in terms of Quercetin metal chelating (poly-) compound) that system, which is made containing such Quercetin metal chelating (poly-) polymer weight content,
0.001-99.9% raw material, is then added in animal feed.
7. a kind of Quercetin metallo-chelate according to claim any one of 1-6 is in the application of animal feed additive,
Characterized in that, the additive is preparing raising pig, fowl, ruminant, aquatic livestock, experimental animal and special economic animal use
Feed in apply.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109394863A (en) * | 2018-12-13 | 2019-03-01 | 吉林化工学院 | A kind of preparation method of rose hip general flavone zinc ion coordination object |
| CN109942532A (en) * | 2019-03-19 | 2019-06-28 | 上海大学 | A kind of multicore flavonoids complex and its preparation method and application |
| CN111418725A (en) * | 2020-03-30 | 2020-07-17 | 浙江省农业科学院 | Application of quercetin as sow feed additive for promoting growth of suckling piglets |
| CN112403522A (en) * | 2020-11-12 | 2021-02-26 | 江南大学 | Mesoporous zirconium quercetin catalyst and application thereof in preparation of alpha, beta-unsaturated alcohol |
| CN112641956A (en) * | 2021-02-09 | 2021-04-13 | 福州大学 | Preparation and application of peptide-metal-drug self-assembly nanoparticles for resisting Alzheimer's disease |
| CN113317398A (en) * | 2021-02-08 | 2021-08-31 | 福建傲农生物科技集团股份有限公司 | Piglet premix and preparation method and application thereof |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109394863A (en) * | 2018-12-13 | 2019-03-01 | 吉林化工学院 | A kind of preparation method of rose hip general flavone zinc ion coordination object |
| CN109942532A (en) * | 2019-03-19 | 2019-06-28 | 上海大学 | A kind of multicore flavonoids complex and its preparation method and application |
| CN109942532B (en) * | 2019-03-19 | 2022-09-02 | 上海大学 | Polynuclear flavonoid complex and preparation method and application thereof |
| CN111418725A (en) * | 2020-03-30 | 2020-07-17 | 浙江省农业科学院 | Application of quercetin as sow feed additive for promoting growth of suckling piglets |
| CN111418725B (en) * | 2020-03-30 | 2022-09-06 | 浙江省农业科学院 | Application of quercetin as sow feed additive for promoting growth of suckling piglets |
| CN112403522A (en) * | 2020-11-12 | 2021-02-26 | 江南大学 | Mesoporous zirconium quercetin catalyst and application thereof in preparation of alpha, beta-unsaturated alcohol |
| CN112403522B (en) * | 2020-11-12 | 2021-11-23 | 江南大学 | Mesoporous zirconium quercetin catalyst and application thereof in preparation of alpha, beta-unsaturated alcohol |
| CN113317398A (en) * | 2021-02-08 | 2021-08-31 | 福建傲农生物科技集团股份有限公司 | Piglet premix and preparation method and application thereof |
| CN112641956A (en) * | 2021-02-09 | 2021-04-13 | 福州大学 | Preparation and application of peptide-metal-drug self-assembly nanoparticles for resisting Alzheimer's disease |
| CN112641956B (en) * | 2021-02-09 | 2022-06-10 | 福州大学 | Preparation and application of peptide-metal-drug self-assembly nanoparticles for resisting Alzheimer's disease |
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Application publication date: 20180209 |