CN107643253A - It is a kind of that whole blood analyser is frozen based on the super continuous integrated spectral of time domain resolution - Google Patents
It is a kind of that whole blood analyser is frozen based on the super continuous integrated spectral of time domain resolution Download PDFInfo
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- CN107643253A CN107643253A CN201710950117.XA CN201710950117A CN107643253A CN 107643253 A CN107643253 A CN 107643253A CN 201710950117 A CN201710950117 A CN 201710950117A CN 107643253 A CN107643253 A CN 107643253A
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Abstract
Whole blood analyser is frozen based on the super continuous integrated spectral of time domain resolution the invention discloses a kind of, the instrument is made up of fuselage and the intraware being assemblied in fuselage；Intraware mainly includes Raspberry Pi, optical fiber laser with super continuous spectrum, spectrometer, sample room, D.C. regulated power supply, touch-screen and accessory.The instrument is used for customs to freezing the detection of whole blood, identifying, build storehouse, trace to the source and protect.The invention has the advantages that employing sample room constant temperature and initial alignment method, the uniformity of test environment and the repeatability of test are improved；Test to freezing whole blood sample, carries out time domain sequences spectra collection, and the time-domain spectroscopy feature difference of the different genera of this method extraction effectively improves the discrimination of different genera by much larger than the SPECTRAL DIVERSITY of conventional single measurement.
Description
Technical field
The present invention relates to a kind of super continuous spectrums laser spectral analysis instrument, more particularly to one kind to connect using time domain resolution laser is super
The whole blood analyser of continuous integrated spectral technology, freeze the test of whole blood sample suitable for people and animal, build storehouse and examination, belong to light
Electrical imaging field.
Background technology
In inlet and outlet field, various countries mostly take the measure strictly controlled to the inlet and outlet of blood product.Because people is with moving
The important biological information such as hereditary capacity containing species in the blood constituent of thing, therefore the access control to it is very tight
Lattice are, it is necessary to which special instrument and equipment is detected.
Due to the particularity of blood product, therefore the requirement to test equipment is contactless, is caused in order to avoid blood is exposed
Denaturation and harm to tester.Existing blood testing equipment is all based on flow cytometry, it is necessary to be carried out to blood sample greatly
The operations such as sampling, dilution, it is high to detection environmental requirement, it is only used for finely detecting, unsuitable customs speeds passage through customs high speed detection
Needs.In addition, the inlet and outlet of blood product in the world follow cryopreservation tube preservation, clearance, the regulation transported at present, i.e., whole blood,
The products such as serum are imported and exported in the environment of must be maintained in subzero 40-80 degree, so customs's detection is solid-state blood
Product.So, biomedical devices on the market can not be competent at.At present, the legal provisions in China forbid the blood product of people to go out
Mouthful, it is allowed to Some Animals blood product exports, because, in order to prevent people's blood is mixed into animal blood by lawless people from being exported,
It a kind of can must quickly distinguish the instrument and method that people freezes fast blood product with animal.
In face of this demand, the present invention proposes a kind of whole blood using the super continuous integrated spectral technology of time domain resolution laser point
Analysis method and corresponding instrument, it is different to freeze the temporal laser super continuum light spectral difference of whole blood with animal according to people, is used for quickly detecting, builds
Storehouse and identification, customs's inlet and outlet detection quarantine departments are facilitated to carry out tracing to the source, differentiate and protecting for frozen blood product.
The content of the invention
It is an object of the invention to provide a kind of time domain to differentiate super continuous spectrums analytical instrument, can obtain people and be frozen entirely with animal
The super continuous integrated spectral of temporal laser of blood, for customs to freezing the detection of whole blood, identifying, build storehouse, trace to the source and protect.
The present invention is achieved like this：
It is proposed by the present invention that freezing whole blood analyser by fuselage and being assemblied in for super continuous integrated spectral is differentiated based on time domain
Intraware composition in fuselage；Intraware mainly include Raspberry Pi, optical fiber laser with super continuous spectrum, spectrometer, sample room,
D.C. regulated power supply, touch-screen and accessory；
Its middle fuselage is in addition to accommodating these intrawares, also fuselage USB interface, keyboard interface, mouse interface and city
Electric switch；Accessory includes USB chargers, some USB lines, one-to-two USB line, HDMI wire, serial port data line, launching fiber
And reception optical fiber；
Optical fiber laser with super continuous spectrum exports the visible super continuous spectrums infrared into by laser fiber output port and swashed
Light is to launching fiber, and the launching fiber other end couples integrating sphere optic fibre input end, to be illuminated to integrating sphere；In integrating sphere
Wall is coated with the equal luminescent material of white dumb light, can carry out even light to the multiple diffusing reflection of light of entrance；Integrating sphere fiber-optic output with
The spectrometer optical fiber interface of spectrometer is coupled by reception optical fiber, and the emergent light of integrating sphere is introduced into spectrometer is analyzed；
Sample room includes specimen holder, integrating sphere and thermostat three parts；Wherein specimen holder is transparency silica glass material, interior
Portion is equipped with freezing whole blood sample to place cryopreservation tube inside cryopreservation tube；Thermostat makes sample room be in a constant room temperature
Environment, stationary temperature make it that all test whole blood samples are consistent with the temperature difference of test environment, and heating is also consistent, and ensure that
The uniformity of test environment；
The civil power of input is converted into direct current by D.C. regulated power supply, and is divided into the output of three tunnels；The first via is providing perseverance
Dc source needed for warm device；Second tunnel is powered with to optical fiber laser with super continuous spectrum；3rd tunnel powers to provide USB
DC voltage needed for device；USB chargers have three USB interface third, USB interface second, USB interface first 5V output supply ports,
Wherein spectrometer USB port is connected with USB interface third and fuselage USB interface respectively by one-to-two USB line, when instrument works,
USB interface third exports 5V DC voltages and powered by spectrometer USB port to spectrometer；When instrument does not work, the nothing of USB interface third
Output, now, spectrometer USB port can connect outer computer by fuselage USB interface, be debugged offline；USB interface second is led to
Cross USB line with Raspberry Pi USB interface third to be connected, to power to Raspberry Pi；USB interface first is connect by USB line and touch-screen USB
Mouth is connected, to be powered to touch-screen；
Raspberry Pi HDMI is connected by HDMI wire with the touch-screen HDMI of touch-screen, to provide touch-screen
Display；Raspberry Pi serial ports is connected with spectrometer serial ports by serial port data line, to be communicated；The connection of Raspberry Pi control mouth is permanent
Warm device, to set thermostat temperature, and receive thermostat has arrived control temperature signal；Keyboard interface passes through USB line and raspberry
USB interface second is sent to be connected, external keyboard insertion keyboard interface can carry out input through keyboard in Raspberry Pi；Mouse interface passes through USB
Line is connected with Raspberry Pi USB interface first, and external mouse insertion mouse interface can carry out mouse action in Raspberry Pi；Raspberry Pi fills
There is main control software, user can carry out the operation that touch operation carries out software by outside key mouse or to touch-screen, carry out man-machine
Interaction；
The whole blood method that freezes that time domain proposed by the present invention differentiates super continuous integrated spectral comprises the following steps：
(1) sample room constant temperature
Specimen holder is put into sample room by user, opens the urban electric power switch of fuselage, and now, D.C. regulated power supply produces output,
So that Raspberry Pi, optical fiber laser with super continuous spectrum, spectrometer, sample room, touch-screen and thermostat are all powered in work shape
State；Raspberry Pi, which is powered, starts main control software, the sample room constant temperature button of user's clicking operation main control software, and main control software produces sound
Should, constant temperature angle value T is to thermostat for setting；Thermostat, which proceeds by, to be heated or cooled, and has temperature sensor in thermostat, when to
During up to predetermined temperature, thermostat return signal completes constant temperature, into next step to main control software；
(2) initial calibration
The initial key for standardization signal of user's clicking operation main control software, main control software produce response, set the collection of spectrometer
Time of integration A；The light that optical fiber laser with super continuous spectrum enters integrating sphere carries out even light through multiple diffusing reflection；Because specimen holder is
Transparency silica glass material, therefore, to light substantially without absorption；Main control software starts spectrometer to the emergent light of integrating sphere by product
A carries out spectra collection between timesharing, obtains reference spectra and is stored in the memory inside Raspberry Pi；
(3) heat up the collection of time domain resolved spectroscopy
User takes out specimen holder, the cryopreservation tube equipped with freezing whole blood sample in low-temperature condition is put into specimen holder, so
Specimen holder is put into sample room, the beginning testing button of user's clicking operation main control software afterwards, main control software produces response, setting
The time interval B that time domain is differentiated, and total length of testing speech C；Optical fiber laser with super continuous spectrum enters the light of integrating sphere through multiple
After diffusing reflection carries out even light, the light that incidence enters whole blood sample will produce absorption, transmission, reflection, a variety of synthesis such as launch again
Effect, then the wall of directive integrating sphere in all directions, there is part light directive whole blood sample again after diffusing reflection, through repeatedly repeatedly
Afterwards, integrated ball integrating sphere fiber-optic output introduces spectrometer by reception optical fiber；Main control software starts spectrometer and accumulated by single
A, time interval B, total length of testing speech C carry out time domain sequences spectra collection, and are stored in the sensor inside Raspberry Pi between timesharing；By
In in the C times in test, the constant temperature angle value of whole blood sample and thermostat set has huge difference, therefore at whole blood sample
In rapid heating condition, its time domain series spectral will also change with the time, the whole blood of different genera in this temperature-rise period,
Due to the difference of the characteristics such as viscosity, colourity, absorption, its time domain series spectral characteristic also will be otherwise varied；
(4) test result analysis
The interpretation of result button of user's clicking operation main control software, main control software produce response, the 3rd step are obtained each
The reference spectra that group time domain sequences spectroscopic data divided by second step obtain, each group time domain sequences combined permeation spectrum is obtained, it is right
It carries out principal component analysis, the fitting of time domain change curve, obtains its time domain and differentiates super continuous spectrums characteristic vector；With basic database
A large amount of known kinds sample characteristic vector carry out pattern-recognition calculating, cluster analysis after, draw the kind of the whole blood sample
Category.
The invention has the advantages that employing sample room constant temperature and initial alignment method, the system of test environment is improved
One property and the repeatability of test；Test to freezing whole blood sample, time domain sequences spectra collection is carried out, because freezing whole blood and sample
There is the temperature difference in product room, time domain sequences spectrum will also change with the time, and the whole blood of different genera is in temperature-rise period, due to viscous
The difference of the characteristics such as degree, colourity, absorption, its time domain series spectral characteristic also will be otherwise varied, therefore the difference of this method extraction
The time-domain spectroscopy feature difference of kind effectively improves the knowledge of different genera by much larger than the SPECTRAL DIVERSITY of conventional single measurement
Not rate.
Brief description of the drawings
Fig. 1 is present system structural representation, in figure：1 --- fuselage；2 --- USB interface third；3 --- USB interface
Second；4 --- USB interface first；5 --- fuselage USB interface；6 --- keyboard interface；7 --- mouse interface；8 --- urban electric power switch；
9 --- D.C. regulated power supply；10 --- USB chargers；11 --- optical fiber laser with super continuous spectrum；12 --- laser fiber is defeated
Exit port；13 --- launching fiber；14 --- integrating sphere optic fibre input end；15 --- integrating sphere fiber-optic output；16 --- sample
Product room；17 --- specimen holder；18 --- cryopreservation tube；19 --- whole blood sample；20 --- integrating sphere；21 --- thermostat；
22 --- reception optical fiber；23 --- spectrometer optical fiber interface；24 --- spectrometer；25 --- spectrometer serial ports；26 --- spectrum
Instrument USB port；27 --- serial port data line；28 --- Raspberry Pi serial ports；29 --- Raspberry Pi control mouth；30 --- Raspberry Pi USB
Interface first；31 --- Raspberry Pi USB interface second；32 --- Raspberry Pi HDMI；33 --- Raspberry Pi USB interface third；
34 --- touch-screen；35 --- HDMI wire；36 --- touch-screen HDMI；37 --- touch-screen USB interface；38 --- one point
Two USB lines；39 --- USB line；40 --- Raspberry Pi.
Note：USB, i.e. Universal Serial Bus, USB；HDMI, i.e. High Definition
Multimedia Interface, HDMI.
Embodiment
The specific embodiment of the invention is as shown in Figure 1.
It is proposed by the present invention that freezing whole blood analyser by fuselage 1 and being assemblied in for super continuous integrated spectral is differentiated based on time domain
Intraware composition in fuselage 1；Intraware mainly include Raspberry Pi 40, optical fiber laser with super continuous spectrum 11, spectrometer 24,
Sample room 16, D.C. regulated power supply 9, touch-screen 34 and accessory；
Its middle fuselage 1 is in addition to accommodating these intrawares, also fuselage USB interface 5, keyboard interface 6, mouse interface 7
With urban electric power switch 8；Accessory includes USB chargers 10, some USB lines 39, one-to-two USB line 38, HDMI wire 35, serial ports number
According to line 27, launching fiber 13 and reception optical fiber 22；
Optical fiber laser with super continuous spectrum 11 exports visible infrared (the present embodiment into by laser fiber output port 12
For 400 to 1700 nanometers) super continuous spectrums laser to launching fiber 13, the connection integrating sphere optical fiber input of the other end of launching fiber 13
End 14, to be illuminated to integrating sphere 20；The inwall of integrating sphere 20 is coated with the equal luminescent material of white dumb light, can be to the light of entrance
Multiple diffusing reflection carries out even light；The spectrometer optical fiber interface 23 of integrating sphere fiber-optic output 15 and spectrometer 24 passes through reception optical fiber
22 connections, the emergent light of integrating sphere 20 is introduced into spectrometer 24, and (the detection spectral region of the present embodiment spectrometer is 400 to 1700
Nanometer) analyzed；
Sample room 16 includes specimen holder 17, integrating sphere 20 and the three parts of thermostat 21；Wherein specimen holder 17 is suprasil
Glass material, internal to place cryopreservation tube 18, the inside of cryopreservation tube 18 is equipped with freezing whole blood sample 19；Thermostat 21 makes sample room
16 are in a constant room temperature environment, and stationary temperature causes the temperature difference one of all test whole blood samples 19 and test environment
Cause, heating is also consistent, and ensure that the uniformity of test environment；
The civil power of input is converted into direct current by D.C. regulated power supply 9, and is divided into the output of three tunnels；The first via is providing perseverance
Dc source needed for warm device 21；Second tunnel is powered with to optical fiber laser with super continuous spectrum 11；3rd tunnel is providing USB
DC voltage needed for charger 10；USB chargers 10 have 4 three USB interface the third 2, USB interface second 3, USB interface first 5V defeated
Go out supply port, wherein spectrometer USB port 26 by one-to-two USB line 38 respectively with USB interface the third 2 and the phase of fuselage USB interface 5
Even, when instrument work, USB interface the third 2 exports 5V DC voltages and powered by spectrometer USB port 26 to spectrometer 24；Work as instrument
When device does not work, USB interface the third 2 is without output, and now, spectrometer USB port 26 can connect outside calculating by fuselage USB interface 5
Machine, debugged offline；USB interface second 3 is connected by the Raspberry Pi USB interface of USB line 39 and Raspberry Pi 40 the third 33, to right
Raspberry Pi 40 is powered；USB interface first 4 is connected by USB line 39 with touch-screen USB interface 37, to be powered to touch-screen 34；
The Raspberry Pi HDMI 32 of Raspberry Pi 40 passes through HDMI wire 35 and the phase of touch-screen HDMI 36 of touch-screen 34
Even, to the offer display of touch-screen 34；The Raspberry Pi serial ports 28 of Raspberry Pi 40 passes through with the spectrometer serial ports 25 of spectrometer 24
Serial port data line 27 connects, to be communicated；The Raspberry Pi control mouth 29 of Raspberry Pi 40 connects thermostat 21, to set perseverance
Temperature, and receive thermostat 21 has arrived control temperature signal；Keyboard interface 6 passes through USB line 39 and Raspberry Pi USB interface second
31 are connected, and external keyboard insertion keyboard interface 6 can carry out input through keyboard in Raspberry Pi 40；Mouse interface 7 by USB line 39 with
Raspberry Pi USB interface first 30 is connected, and external mouse insertion mouse interface 7 can carry out mouse action in Raspberry Pi 40；Raspberry Pi
40 are equipped with main control software, and user can carry out the operation that touch operation carries out software by outside key mouse or to touch-screen 34, enter
Row man-machine interaction；
The whole blood method that freezes that time domain proposed by the present invention differentiates super continuous integrated spectral comprises the following steps：
(1) sample room constant temperature
Specimen holder 17 is put into sample room 16 by user, opens the urban electric power switch 8 of fuselage 1, now, D.C. regulated power supply 9 produces
Raw output so that Raspberry Pi 40, optical fiber laser with super continuous spectrum 11, spectrometer 24, sample room 16, touch-screen 34 and thermostat
21 be all powered it is in running order；Raspberry Pi 40, which is powered, starts main control software, and the sample room of user's clicking operation main control software is permanent
Warm button, main control software produce response, set constant temperature angle value T (the present embodiment is 20 degree) to thermostat 21；Thermostat 21 is opened
Beginning is heated or cooled, and has temperature sensor in thermostat 21, when reaching predetermined temperature T, the return signal of thermostat 21 is given
Main control software, constant temperature is completed, into next step；
(2) initial calibration
The initial key for standardization signal of user's clicking operation main control software, main control software produce response, and setting spectrometer 24 is adopted
Collect time of integration A (the present embodiment is 200 milliseconds)；Optical fiber laser with super continuous spectrum 11 enters the light of integrating sphere 20 through repeatedly unrestrained
Reflection carries out even light；Because specimen holder 17 is transparency silica glass material, therefore, to light substantially without absorption；Main control software opens
Dynamic spectrometer 24 carries out spectra collection to the emergent light of integrating sphere 20 by time of integration A, obtains reference spectra and is stored in Raspberry Pi
Memory inside 40；
(3) heat up the collection of time domain resolved spectroscopy
User takes out specimen holder 17, and will be in low-temperature condition (the present embodiment is subzero 60 degree) is equipped with freezing whole blood sample
19 cryopreservation tube 18 is put into specimen holder 17, and specimen holder 17 then is put into sample room 16, and user's clicking operation main control software is opened
Beginning testing button, main control software produce response, the time interval B (notes that setting time domain is differentiated：That is step-length, the present embodiment are 5 seconds),
And total length of testing speech C (the present embodiment is 1 minute)；Optical fiber laser with super continuous spectrum 11 enters the light of integrating sphere 20 through multiple
After diffusing reflection carries out even light, incidence enter whole blood sample 19 light will produce absorption, transmission, reflection, launch again etc. it is a variety of comprehensive
Effect, then the wall of directive integrating sphere 20 in all directions are closed, has part light directive whole blood sample 19 again after diffusing reflection, through more
It is secondary repeatedly after, the integrated integrating sphere fiber-optic output 15 of ball 20 pass through reception optical fiber 22 introduce spectrometer 24；Main control software starts
Spectrometer 24 is by single time of integration A, time interval B, (the present embodiment is common for total length of testing speech C progress time domain sequences spectra collection
Obtain 12 groups of integrated spectral data), and it is stored in the sensor inside Raspberry Pi 40；Due within the C times of test, whole blood sample
The 19 constant temperature angle value set with thermostat 21 have huge difference, therefore whole blood sample 19 is in rapid heating condition, at that time
Domain series spectral will also change with the time, and the whole blood of different genera is in this temperature-rise period, due to viscosity, colourity, absorption
Etc. the difference of characteristic, its time domain series spectral characteristic also will be otherwise varied；
(4) test result analysis
The interpretation of result button of user's clicking operation main control software, main control software produce response, the 3rd step are obtained each
The reference spectra that group time domain sequences spectroscopic data divided by second step obtain, each group time domain sequences combined permeation spectrum is obtained, it is right
It carries out principal component analysis, the fitting of time domain change curve, obtains its time domain and differentiates super continuous spectrums characteristic vector；With basic database
A large amount of known kinds sample characteristic vector carry out pattern-recognition calculating, cluster analysis after, draw the whole blood sample 19
Kind.
Claims (1)
1. a kind of freeze whole blood analyser based on the super continuous integrated spectral of time domain resolution, by fuselage (1) and fuselage (1) is assemblied in
Interior intraware composition；Intraware includes Raspberry Pi (40), optical fiber laser with super continuous spectrum (11), spectrometer (24), sample
Product room (16), D.C. regulated power supply (9), touch-screen (34) and accessory；It is characterized in that：
Described fuselage (1) is in addition to accommodating these intrawares, and also fuselage USB interface (5), keyboard interface (6), mouse connect
Mouth (7) and urban electric power switch (8)；
Described accessory include USB chargers (10), some USB lines (39), one-to-two USB line (38), HDMI wire (35),
Serial port data line (27), launching fiber (13) and reception optical fiber (22)；
Described optical fiber laser with super continuous spectrum (11) by laser fiber output port (12) export it is visible in it is infrared
Super continuous spectrums laser is to launching fiber (13), and launching fiber (13) other end couples integrating sphere optic fibre input end (14), to right
Integrating sphere (20) is illuminated；Integrating sphere (20) inwall is coated with the equal luminescent material of white dumb light, and the light of entrance repeatedly can be overflow
Reflection carries out even light；The spectrometer optical fiber interface (23) of integrating sphere fiber-optic output (15) and spectrometer (24) passes through reception optical fiber
(22) couple, the emergent light of integrating sphere (20) is introduced into spectrometer (24) is analyzed；
Described sample room (16) includes specimen holder (17), integrating sphere (20) and thermostat (21) three parts；Wherein specimen holder
(17) it is transparency silica glass material, it is internal to place cryopreservation tube (18), freezing whole blood sample is housed inside cryopreservation tube (18)
(19)；Thermostat (21) makes sample room (16) be in a constant room temperature environment, and stationary temperature causes all test whole bloods
Sample (19) is consistent with the temperature difference of test environment, and heating is also consistent, and ensure that the uniformity of test environment；
The civil power of input is converted into direct current by described D.C. regulated power supply (9), and is divided into the output of three tunnels；The first via is carrying
For the dc source needed for thermostat (21)；Second tunnel is powered with to optical fiber laser with super continuous spectrum (11)；Use on 3rd tunnel
To provide the DC voltage needed for USB chargers (10)；USB chargers (10) have USB interface third (2), USB interface second (3),
(4) three 5V of USB interface first output supply ports, wherein spectrometer USB port (26) by one-to-two USB line (38) respectively with
USB interface third (2) and fuselage USB interface (5) are connected, and when instrument works, USB interface third (2) output 5V DC voltages pass through
Spectrometer USB port (26) is powered to spectrometer (24)；When instrument does not work, USB interface third (2) is without output, now, spectrometer
USB port (26) can connect outer computer by fuselage USB interface (5), be debugged offline；USB interface second (3) passes through USB
Line (39) is connected with the Raspberry Pi USB interface third (33) of Raspberry Pi (40), to be powered to Raspberry Pi (40)；USB interface first (4)
It is connected by USB line (39) with touch-screen USB interface (37), to be powered to touch-screen (34)；
The Raspberry Pi HDMI (32) of described Raspberry Pi (40) passes through HDMI wire (35) and the touch-screen of touch-screen (34)
HDMI (36) is connected, to provide display to touch-screen (34)；The Raspberry Pi serial ports (28) and spectrometer of Raspberry Pi (40)
(24) spectrometer serial ports (25) is connected by serial port data line (27), to be communicated；The Raspberry Pi control of Raspberry Pi (40)
Donsole (29) connection thermostat (21), to set thermostat temperature, and receive thermostat (21) has arrived control temperature signal；Key
Disk interface (6) is connected by USB line (39) with Raspberry Pi USB interface second (31), and external keyboard insertion keyboard interface (6) can set
The certain kind of berries, which is sent, carries out input through keyboard in (40)；Mouse interface (7) is connected by USB line (39) with Raspberry Pi USB interface first (30), outside
Mouse insertion mouse interface (7) can carry out mouse action in Raspberry Pi (40)；Raspberry Pi (40) is equipped with main control software, Yong Huke
To carry out the operation that touch operation carries out software by outside key mouse or to touch-screen (34), man-machine interaction is carried out.
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|---|---|---|---|---|
| JP2005140546A (en) * | 2003-11-04 | 2005-06-02 | Keiichiro Ogawa | Low-temperature diffuse reflection measuring apparatus, sample holder used for the same, and low-temperature diffuse reflection spectrum measuring method |
| CN202502049U (en) * | 2012-02-21 | 2012-10-24 | 中国工程物理研究院流体物理研究所 | Measuring device for refractive indexes of transparent fluids under high pressure |
| CN105628679A (en) * | 2016-03-23 | 2016-06-01 | 中国科学院上海技术物理研究所 | Blood identification instrument based on infrared Raman ultraviolet fluorescence super-continuum spectrum |
| CN105759066A (en) * | 2016-04-26 | 2016-07-13 | 绍兴普施康生物科技有限公司 | Full-automatic hemostasis examination analyzer and method |
| CN207280941U (en) * | 2017-10-13 | 2018-04-27 | 中国科学院上海技术物理研究所 | Whole blood analyser is frozen based on the super continuous integrated spectral of time domain resolution |
-
2017
- 2017-10-13 CN CN201710950117.XA patent/CN107643253B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005140546A (en) * | 2003-11-04 | 2005-06-02 | Keiichiro Ogawa | Low-temperature diffuse reflection measuring apparatus, sample holder used for the same, and low-temperature diffuse reflection spectrum measuring method |
| CN202502049U (en) * | 2012-02-21 | 2012-10-24 | 中国工程物理研究院流体物理研究所 | Measuring device for refractive indexes of transparent fluids under high pressure |
| CN105628679A (en) * | 2016-03-23 | 2016-06-01 | 中国科学院上海技术物理研究所 | Blood identification instrument based on infrared Raman ultraviolet fluorescence super-continuum spectrum |
| CN105759066A (en) * | 2016-04-26 | 2016-07-13 | 绍兴普施康生物科技有限公司 | Full-automatic hemostasis examination analyzer and method |
| CN207280941U (en) * | 2017-10-13 | 2018-04-27 | 中国科学院上海技术物理研究所 | Whole blood analyser is frozen based on the super continuous integrated spectral of time domain resolution |
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