CN107617451B - 一种微流控芯片的驱动方法和驱动系统 - Google Patents

一种微流控芯片的驱动方法和驱动系统 Download PDF

Info

Publication number
CN107617451B
CN107617451B CN201710910461.6A CN201710910461A CN107617451B CN 107617451 B CN107617451 B CN 107617451B CN 201710910461 A CN201710910461 A CN 201710910461A CN 107617451 B CN107617451 B CN 107617451B
Authority
CN
China
Prior art keywords
driving signal
period
electrode
contact angle
driving
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201710910461.6A
Other languages
English (en)
Chinese (zh)
Other versions
CN107617451A (zh
Inventor
龙凤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BOE Technology Group Co Ltd
Beijing BOE Optoelectronics Technology Co Ltd
Original Assignee
BOE Technology Group Co Ltd
Beijing BOE Optoelectronics Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BOE Technology Group Co Ltd, Beijing BOE Optoelectronics Technology Co Ltd filed Critical BOE Technology Group Co Ltd
Priority to CN201710910461.6A priority Critical patent/CN107617451B/zh
Publication of CN107617451A publication Critical patent/CN107617451A/zh
Priority to JP2019569427A priority patent/JP7280199B2/ja
Priority to EP18861776.5A priority patent/EP3689463A4/en
Priority to US16/338,811 priority patent/US11446656B2/en
Priority to PCT/CN2018/094943 priority patent/WO2019062267A1/zh
Application granted granted Critical
Publication of CN107617451B publication Critical patent/CN107617451B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • B01L3/502792Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics for moving individual droplets on a plate, e.g. by locally altering surface tension
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0673Handling of plugs of fluid surrounded by immiscible fluid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0424Dielectrophoretic forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0427Electrowetting

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Micromachines (AREA)
CN201710910461.6A 2017-09-29 2017-09-29 一种微流控芯片的驱动方法和驱动系统 Active CN107617451B (zh)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CN201710910461.6A CN107617451B (zh) 2017-09-29 2017-09-29 一种微流控芯片的驱动方法和驱动系统
JP2019569427A JP7280199B2 (ja) 2017-09-29 2018-07-09 デジタルマイクロ流体チップ用の駆動方法及び駆動システム
EP18861776.5A EP3689463A4 (en) 2017-09-29 2018-07-09 CONTROL PROCESS AND DRIVER SYSTEM FOR USE IN A DIGITAL MICROFLUIDIC CHIP
US16/338,811 US11446656B2 (en) 2017-09-29 2018-07-09 Driving method and driving system for digital microfluidic chip
PCT/CN2018/094943 WO2019062267A1 (zh) 2017-09-29 2018-07-09 用于数字微流控芯片的驱动方法和驱动系统

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710910461.6A CN107617451B (zh) 2017-09-29 2017-09-29 一种微流控芯片的驱动方法和驱动系统

Publications (2)

Publication Number Publication Date
CN107617451A CN107617451A (zh) 2018-01-23
CN107617451B true CN107617451B (zh) 2019-06-04

Family

ID=61091103

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710910461.6A Active CN107617451B (zh) 2017-09-29 2017-09-29 一种微流控芯片的驱动方法和驱动系统

Country Status (5)

Country Link
US (1) US11446656B2 (https=)
EP (1) EP3689463A4 (https=)
JP (1) JP7280199B2 (https=)
CN (1) CN107617451B (https=)
WO (1) WO2019062267A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107617451B (zh) * 2017-09-29 2019-06-04 京东方科技集团股份有限公司 一种微流控芯片的驱动方法和驱动系统
CN108654711B (zh) * 2018-06-07 2020-03-31 西南科技大学 一种降低电场下固液界面粘-滑行为的方法
CN109126917B (zh) * 2018-10-09 2020-04-10 京东方科技集团股份有限公司 微流控芯片及其驱动方法
CN109622085B (zh) 2019-01-31 2021-12-24 京东方科技集团股份有限公司 微流控芯片的驱动方法及其装置、微流控系统
CN110010086B (zh) 2019-03-29 2020-12-22 上海中航光电子有限公司 电润湿面板的驱动方法
CN112415357B (zh) * 2019-08-21 2025-09-16 佛山奥素博新科技有限公司 数字微流控设备与dmf驱动系统连接的检测方法、系统
CN113805035B (zh) * 2020-06-17 2025-08-22 佛山奥素博新科技有限公司 一种数字微流控系统的检测电路和检测方法
CN120576153B (zh) * 2024-11-14 2025-11-14 康沃思(天津)生物科技有限公司 基于声束流实现微水锤效应的方法及装置

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102350380A (zh) * 2011-09-26 2012-02-15 复旦大学 一种透明单平面单极性数字微流体芯片及其控制方法
CN104035796A (zh) * 2014-06-13 2014-09-10 苏州大学 一种ewod芯片液滴驱动方法及系统
CN105233887A (zh) * 2015-08-31 2016-01-13 中国科学院深圳先进技术研究院 一种基于介电润湿的微液滴驱动器件及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3791999B2 (ja) * 1997-03-24 2006-06-28 株式会社アドバンス 液体微粒子ハンドリング装置
CN102175744A (zh) 2011-01-06 2011-09-07 复旦大学 一种数字微流控技术的电化学传感器芯片
US8173000B1 (en) 2011-01-18 2012-05-08 Sharp Kabushiki Kaisha Active matrix device and method of driving the same
US8828336B2 (en) 2011-02-02 2014-09-09 Sharp Kabushiki Kaisha Active matrix device
CN102600919B (zh) 2012-03-20 2014-10-01 复旦大学 一种限制数字微流控芯片液滴单向输运的方法
CN102879453B (zh) 2012-09-04 2015-08-26 吴传勇 基于电泳来操控液体中的带电粒子的方法及器件
CN102824933B (zh) 2012-09-20 2014-09-03 复旦大学 一种单向液滴输运的数字微流芯片电极配置方法
US9254485B2 (en) * 2012-12-17 2016-02-09 Taiwan Semiconductor Manufacturing Company, Ltd. Systems and methods for an integrated bio-entity manipulation and processing device
US9239328B2 (en) * 2012-12-17 2016-01-19 Taiwan Semiconductor Manufacturing Company, Ltd. Systems and methods for an integrated bio-entity manipulation and processing semiconductor device
US9808800B2 (en) * 2015-04-10 2017-11-07 Unversity Of Macau Electrode-voltage waveform for droplet-velocity and chip-lifetime improvements of digital microfluidic systems
US10857537B2 (en) * 2015-07-06 2020-12-08 Illumina, Inc. Balanced AC modulation for driving droplet operations electrodes
CN107617451B (zh) 2017-09-29 2019-06-04 京东方科技集团股份有限公司 一种微流控芯片的驱动方法和驱动系统

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102350380A (zh) * 2011-09-26 2012-02-15 复旦大学 一种透明单平面单极性数字微流体芯片及其控制方法
CN104035796A (zh) * 2014-06-13 2014-09-10 苏州大学 一种ewod芯片液滴驱动方法及系统
CN105233887A (zh) * 2015-08-31 2016-01-13 中国科学院深圳先进技术研究院 一种基于介电润湿的微液滴驱动器件及其制备方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
effect of electrode switching sequence on EWOD droplet manipulation: a simulation study;SadAabadi H;《Proceeding of the 8th international conference on nanochannels,microchannels and minichannels》;20111231;摘要
基于介电润湿的数字微流控系统中液滴运动性能研究;常银霞;《中国博士学位论文全文数据库 信息科技辑》;20140315;全文

Also Published As

Publication number Publication date
JP7280199B2 (ja) 2023-05-23
US20210362148A1 (en) 2021-11-25
JP2020534991A (ja) 2020-12-03
EP3689463A4 (en) 2021-11-24
US11446656B2 (en) 2022-09-20
EP3689463A1 (en) 2020-08-05
WO2019062267A1 (zh) 2019-04-04
CN107617451A (zh) 2018-01-23

Similar Documents

Publication Publication Date Title
CN107617451B (zh) 一种微流控芯片的驱动方法和驱动系统
EP3409366B1 (en) Microfluidic device with multiple temperature zones and enhanced temperature control
CN109894167B (zh) 微流控芯片
CA3033398A1 (en) Multiplexed droplet actuation and sensing in digital microfluidics
CN109894169B (zh) 电润湿面板及其工作方法
CN212158459U (zh) 基于介电润湿数字微流控的液滴检测系统
CN108405004B (zh) 一种液滴生成控制方法及其系统
TW200909338A (en) Autonomous microfluidic apparatus
CN110694702B (zh) 一种微流控芯片及驱动方法、微流控装置
KR20150013178A (ko) 반응 생성물의 실시간 샘플링 방법
US20070128082A1 (en) Microflow coverage ratio control device
CN208407027U (zh) 一种液滴生成控制系统
CN104035796A (zh) 一种ewod芯片液滴驱动方法及系统
CN202465675U (zh) 流量法控制两种动态生化信号快速切换刺激的微流控剪切装置
CN109603938A (zh) 一种微流控装置、液滴识别及控制方法
CN101441194B (zh) 低电压芯片电泳多段式循环式施加电压的控制系统和方法
CN210357208U (zh) 一种便携式可拼接数字微流控驱动电路、装置及系统
CN111229343B (zh) 一种数字微流控平台的拼接系统的拼接方法
KR20120133899A (ko) 관성센서의 구동제어모듈 및 구동제어방법
CN109806803A (zh) 一种具有电润湿阈门的微流体混合装置及其控制方法
CN113996353A (zh) 一种微滴生成装置、生成方法及用途
CN223295747U (zh) 一种声场和电场调控的生化液滴样本制备装置
CN101670998B (zh) 点面电极系统及利用该系统进行微流体驱动的方法
KR101475440B1 (ko) 미세유체회로소자
CN207655159U (zh) 一种基于电频率控制的微液滴驱动装置

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant