CN107616971A - A kind of liquid spray bandage, wound spray liquid and preparation method thereof - Google Patents

A kind of liquid spray bandage, wound spray liquid and preparation method thereof Download PDF

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Publication number
CN107616971A
CN107616971A CN201710700673.1A CN201710700673A CN107616971A CN 107616971 A CN107616971 A CN 107616971A CN 201710700673 A CN201710700673 A CN 201710700673A CN 107616971 A CN107616971 A CN 107616971A
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CN
China
Prior art keywords
wound
disinfectant
liquid
spray liquid
polymeric viscosifier
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710700673.1A
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Chinese (zh)
Inventor
李建全
和利蕊
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Sane Medical Supplies Ltd Co
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Sane Medical Supplies Ltd Co
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Publication date
Application filed by Sane Medical Supplies Ltd Co filed Critical Sane Medical Supplies Ltd Co
Priority to CN201710700673.1A priority Critical patent/CN107616971A/en
Publication of CN107616971A publication Critical patent/CN107616971A/en
Pending legal-status Critical Current

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Abstract

The invention discloses a kind of liquid spray bandage, wound spray liquid and preparation method thereof, wound spray liquid includes the disinfectant and polymeric viscosifier mixed, and disinfectant includes one or more of mixing in quaternary ammonium salts disinfectant, guanidine disinfectant, hydrogen peroxide, Iodophor and Triclosan.Because wound spray liquid includes the disinfectant and polymeric viscosifier that mix; wound spray liquid is sprayed on wound surface and forms layer protecting film; both disinfection can be played a part of to wound; wound can be obstructed with extraneous again, waterproof and breathable, wound spray liquid directly sprays film forming on wound top layer; adhesive force is strong; it is difficult for drop-off and damaged, wound can be protected for a long time, aerosol nursing use is more convenient.

Description

A kind of liquid spray bandage, wound spray liquid and preparation method thereof
Technical field
The present invention relates to human body Wound care products, and in particular to a kind of liquid spray bandage, wound spray liquid and its Preparation method.
Background technology
The Wound care products bandage that market occurs, it is mostly by an elongated adhesive plaster, centre is accompanied by fritter leaching The sliver for crossing medicine is formed, and is played temporary transient hemostasis, is protected the effect of the surface of a wound.It should be noted that the time used should not mistake It is long.If using it too long, the adhesive plaster of adhesive bandage outer layer is airtight.Wound and the skin whitening of wound circumference will be made, become The soft secondary infection for causing bacterium.Can thus wound be set more to deteriorate.In addition, once soaked, must change, it is no Then bacterium can be easier to enter wound, make wound deterioration.
Another spraying sterilizing agent occurred on the market, easily slid from wound, can not only protect wound for a long time It is also easy to be infected with clothing.
The content of the invention
The application provide it is a kind of it is easy to use, nursing efficacy is good and be capable of the liquid spray bandage of digital preservation wound, Wound spray liquid and preparation method thereof.
According in a first aspect, provide a kind of wound spray liquid in a kind of embodiment, including the disinfectant mixed and Polymeric viscosifier, disinfectant include quaternary ammonium salts disinfectant, guanidine disinfectant, hydrogen peroxide, Iodophor and Triclosan In one or more of mixing.
Further, polymeric viscosifier is the polymer with atomization, and polymeric viscosifier polymerize including anionic species Thickener or nonionic Type of Collective thickener.
Further, anionic species polymeric viscosifier is PAA & sodium acryloyldimethyl taurate copolymers & different ten Six alkane & polysorbate 80s, PAA & sodium acryloyldimethyl taurate copolymers & polyisobutene & octyl-decyl glucose One or more of mixing in glycosides, PAA & sodium acryloyldimethyl taurate & dimethacrylate sodium copolymers.
Further, nonionic Type of Collective thickener is polyacrylate cross-linked polymer -6, the different alkanes of polyacrylamide & One or more of mixing in hydrocarbon C13-14& lauryl alcohols -7.
Further, the viscosity of wound spray liquid is 0~2000mPas.
According to second aspect, a kind of liquid spray bandage is provided in a kind of embodiment, including sprayer unit and right will Any one of 1 to 5 wound spray liquid is sought, sprayer unit includes spraying pump head and solution bottle, and wound spray liquid is placed in solution bottle Interior, spraying pump head is arranged on solution bottle.
According to the third aspect, a kind of wound spraying liquid and preparation method thereof is provided in a kind of embodiment, comprised the following steps:
According to the compatibility situation of disinfectant, resistance to ionic, anti-UV irradiation performances and pulverability, select what is be adapted to therewith Polymeric viscosifier;
Polymeric viscosifier is added in aqueous phase under stirring, until forming uniform gel, is designated as A phases;
Configuration meets the disinfectant solution of national regulation content, is designated as B phases;
Under stirring, B phases are slowly added in A phases, are mixedly configured into wound spray liquid.
Further, disinfectant includes quaternary ammonium salts disinfectant, guanidine disinfectant, hydrogen peroxide, Iodophor and trichlorine hydroxyl One or more of mixing in diphenyl ether.
Further, polymeric viscosifier is the polymer with good atomization, and polymeric viscosifier includes anionic species Polymeric viscosifier or nonionic Type of Collective thickener.
Wound spraying liquid and preparation method thereof as claimed in claim 9, it is characterised in that the anionic species polymeric viscosifier For PAA & sodium acryloyldimethyl taurate copolymers & isohexadecane & polysorbate 80s, PAA & acryloyls two N-methyltaurine sodium copolymer & polyisobutene & octyl-decyls glucoside, PAA & sodium acryloyldimethyl taurates & bis- One or more of mixing in Sodium methacrylate copolymer.Nonionic Type of Collective thickener is polyacrylate cross-linked polymeric One or more of mixing in thing -6, polyacrylamide & isoparaffin C13-14& lauryl alcohols -7.
Liquid spray bandage, wound spray liquid according to above-described embodiment and preparation method thereof, due to wound spray liquid Including the disinfectant and polymeric viscosifier mixed, wound spray liquid is sprayed on wound surface and forms layer protecting film, both Disinfection can be played a part of to wound, wound can be obstructed with extraneous again, waterproof and breathable, wound spray liquid directly exists Wound top layer sprays film forming, and adhesive force is strong, difficult for drop-off and damaged, can protect wound for a long time, and aerosol nursing uses It is more convenient.
Brief description of the drawings
Fig. 1 is a kind of flow chart of wound spraying liquid and preparation method thereof in embodiment.
Embodiment
The present invention is described in further detail below by embodiment combination accompanying drawing.
Embodiment one:
A kind of wound spray liquid is present embodiments provided, this wound spray liquid is used for wound care, is injected in human body wound Upper formation liquid spray bandage.
Specifically, wound spray liquid includes the disinfectant and polymeric viscosifier mixed.Disinfectant is used for human body Sterilization, polymeric viscosifier are used to disinfectant together condensing into diaphragm.
Disinfectant is included according to GB 27954《Mucosal disinfectant requirement》Quaternary ammonium salts disinfectant, guanidine sterilization One or more of mixing in agent, hydrogen peroxide, Iodophor and Triclosan.
Polymeric viscosifier is the polymer with atomization, and polymeric viscosifier includes anionic species polymeric viscosifier or non- Ionic species polymeric viscosifier.Anionic species polymeric viscosifier is PAA & sodium acryloyldimethyl taurate copolymers & different ten Six alkane & polysorbate 80s, PAA & sodium acryloyldimethyl taurate copolymers & polyisobutene & octyl-decyl glucose The polymer of the good atomizations of tool such as glycosides, PAA & sodium acryloyldimethyl taurate & dimethacrylate sodium copolymers In one or more of mixing.Nonionic Type of Collective thickener is polyacrylate cross-linked polymer -6, the different chains of polyacrylamide & One or more of mixing in the polymer of the good atomization of grade tool of alkane C13-14& lauryl alcohols -7.
Polymeric viscosifier is needed according to the compatibility situation of disinfectant, resistance to ionic, anti-UV irradiation performances and pulverability Selection so that polymeric viscosifier matches with disinfectant.
Degree of the polymeric viscosifier in wound spray liquid selects also according to disinfectant, ensures wound spray liquid Viscosity be 0~2000mPas so that quickly can condense into diaphragm in human body wound after spraying.
The wound spray liquid that the present embodiment provides, because the disinfectant that wound spray liquid includes mixing and polymerization increase Thick dose, wound spray liquid is sprayed on wound surface and forms layer protecting film, can both play a part of disinfection to wound, again Wound can be obstructed with extraneous, waterproof and breathable, wound spray liquid directly sprays film forming on wound top layer, and adhesive force is strong, is not easy Come off and damaged, can protect wound for a long time, aerosol nursing use is more convenient.
Embodiment two:
A kind of liquid spray bandage is present embodiments provided, wound spray liquid is ejected into people by this liquid spray bandage A protective layer can be quickly formed on body wound to protect wound.
The liquid spray bandage of the present embodiment includes the wound spray liquid in sprayer unit and above-described embodiment one.Spraying Device includes spraying pump head and solution bottle, and wound spray liquid is placed in solution bottle, and spraying pump head is arranged on solution bottle, can be led to Spraying pump head is crossed to eject the wound spray liquid in solution bottle for protecting wound.
The liquid spray bandage of the present embodiment is only needed towards a wound location gently spray, the sterilization sprayed after several seconds Liquid forms layer protecting film in wound surface, can both play a part of disinfection to wound, again can be by wound and the external world Barrier, waterproof and breathable.At will activity, bathing are all without influence wound healing.A couple of days wound is just almost good, and film can become Dry, edge departs from skin, is torn it down with hand, convenient and swift.
Compared with traditional bandage, be not in alice, situations such as departing from, be especially suitable for the frequent activity such as joint The movability colony such as position or children.
Compared with traditional spraying sterilizing agent, it will not slide or flow from wound, can not only protect wound for a long time Mouth is also easy to be infected with clothing.The liquid spray adhesive bandage of the present invention can form layer protecting film in wound, make wound for a long time In guard mode.
Embodiment three:
Wound spraying liquid and preparation method thereof is provided in the present embodiment, the wound spray liquid in embodiment one can be prepared.
Specifically, as shown in figure 1, the wound spraying liquid and preparation method thereof of the present embodiment comprises the following steps:
S001:Select disinfectant and polymeric viscosifier;
A kind of disinfectant is first selected, compatibility situation, resistance to ionic, anti-UV irradiation performances and spraying further according to disinfectant Performance, select the polymeric viscosifier being adapted to therewith.
Specifically, quaternary ammonium salts disinfectant, guanidine disinfectant, hydrogen peroxide, Iodophor and trichlorine hydroxyl may be selected in disinfectant One or more of mixing in diphenyl ether.
Anionic species polymeric viscosifier or nonionic Type of Collective thickener may be selected in polymeric viscosifier.Anionic species polymerization increases Thick dose is PAA & sodium acryloyldimethyl taurate copolymers & isohexadecane & polysorbate 80s, PAA & propylene Acyl dimethyltaurine sodium copolymer & polyisobutene & octyl-decyls glucoside, PAA & acryloyldimethyl taurines One or more of mixing in the polymer of the good atomization of tool such as sodium & dimethacrylate sodium copolymers.Nonionic is birdsed of the same feather flock together Conjunction thickener is that the tools such as polyacrylate cross-linked polymer -6, polyacrylamide & isoparaffin C13-14& lauryl alcohols -7 are good One or more of mixing in the polymer of atomization.
S002:Prepare A phases;
Polymeric viscosifier is added in aqueous phase under stirring, until forming uniform gel, is designated as A phases.Can be artificial Stirring is stirred by mixer.
S003:Prepare B phases;
Configuration meets the disinfectant solution of national regulation content, is designated as B phases.
S004:Prepare wound spray liquid.
Under stirring, B phases are slowly added in A phases, are mixedly configured into wound spray liquid.Manually it can stir or pass through Mixer stirs.
The wound spraying liquid and preparation method thereof that the present embodiment provides, the wound spray liquid prepared, can be used in wound protection. For example, wound spray liquid is placed in injection apparatus, wound spray liquid is ejected on wound and forms diaphragm by injection apparatus.
Use above specific case is illustrated to the present invention, is only intended to help and is understood the present invention, not limiting The system present invention.For those skilled in the art, according to the thought of the present invention, can also make some simple Deduce, deform or replace.

Claims (10)

1. a kind of wound spray liquid, it is characterised in that including the disinfectant and polymeric viscosifier mixed, the disinfectant Mixed including the one or more in quaternary ammonium salts disinfectant, guanidine disinfectant, hydrogen peroxide, Iodophor and Triclosan Close.
2. wound spray liquid as claimed in claim 1, it is characterised in that the polymeric viscosifier is poly- with atomization Compound, the polymeric viscosifier include anionic species polymeric viscosifier or nonionic Type of Collective thickener.
3. wound spray liquid as claimed in claim 2, it is characterised in that the anionic species polymeric viscosifier is acrylic acid Sodium & sodium acryloyldimethyl taurate copolymers & isohexadecane & polysorbate 80s, PAA & acryloyldimethyl ox sulphurs Sour sodium copolymer & polyisobutene & octyl-decyls glucoside, PAA & sodium acryloyldimethyl taurate & dimethyl allenes One or more of mixing in sour sodium copolymer.
4. wound spray liquid as claimed in claim 2, it is characterised in that the nonionic Type of Collective thickener is polyacrylic acid One or more of mixing in ester cross-linked polymer -6, polyacrylamide & isoparaffin C13-14& lauryl alcohols -7.
5. wound spray liquid as claimed in claim 1, it is characterised in that the viscosity of the wound spray liquid be 0~ 2000mPa·s。
6. a kind of liquid spray bandage, it is characterised in that including the wound described in sprayer unit and any one of claim 1 to 5 Mouth spray liquid, the sprayer unit include spraying pump head and solution bottle, and the wound spray liquid is placed in the solution bottle, institute Spraying pump head is stated on the solution bottle.
The liquid and preparation method thereof 7. a kind of wound is sprayed, it is characterised in that comprise the following steps:
According to the compatibility situation of disinfectant, resistance to ionic, anti-UV irradiation performances and pulverability, the polymerization being adapted to therewith is selected Thickener;
Polymeric viscosifier is added in aqueous phase under stirring, until forming uniform gel, is designated as A phases;
Configuration meets the disinfectant solution of national regulation content, is designated as B phases;
Under stirring, B phases are slowly added in A phases, are mixedly configured into wound spray liquid.
The liquid and preparation method thereof 8. wound as claimed in claim 7 is sprayed, it is characterised in that the disinfectant disappears including quaternary ammonium salts One or more of mixing in toxic agent, guanidine disinfectant, hydrogen peroxide, Iodophor and Triclosan.
The liquid and preparation method thereof 9. wound as claimed in claim 7 is sprayed, it is characterised in that the polymeric viscosifier is with good The polymer of atomization, the polymeric viscosifier include anionic species polymeric viscosifier or nonionic Type of Collective thickener.
The liquid and preparation method thereof 10. wound as claimed in claim 9 is sprayed, it is characterised in that the anionic species polymeric viscosifier For PAA & sodium acryloyldimethyl taurate copolymers & isohexadecane & polysorbate 80s, PAA & acryloyls two N-methyltaurine sodium copolymer & polyisobutene & octyl-decyls glucoside, PAA & sodium acryloyldimethyl taurates & bis- One or more of mixing in Sodium methacrylate copolymer;Nonionic Type of Collective thickener is polyacrylate cross-linked polymeric One or more of mixing in thing -6, polyacrylamide & isoparaffin C13-14& lauryl alcohols -7.
CN201710700673.1A 2017-08-16 2017-08-16 A kind of liquid spray bandage, wound spray liquid and preparation method thereof Pending CN107616971A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710700673.1A CN107616971A (en) 2017-08-16 2017-08-16 A kind of liquid spray bandage, wound spray liquid and preparation method thereof

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Application Number Priority Date Filing Date Title
CN201710700673.1A CN107616971A (en) 2017-08-16 2017-08-16 A kind of liquid spray bandage, wound spray liquid and preparation method thereof

Publications (1)

Publication Number Publication Date
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102772801A (en) * 2012-08-10 2012-11-14 江苏长泰药业有限公司 Wound spray for treating bruises and preparation method of wound spray
US20150007848A1 (en) * 2011-12-16 2015-01-08 Henkel Ag & Co. Kgaa Hair cosmetics
CN106714767A (en) * 2014-06-11 2017-05-24 汉高股份有限及两合公司 Hair care product and process for hair caring

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150007848A1 (en) * 2011-12-16 2015-01-08 Henkel Ag & Co. Kgaa Hair cosmetics
CN102772801A (en) * 2012-08-10 2012-11-14 江苏长泰药业有限公司 Wound spray for treating bruises and preparation method of wound spray
CN106714767A (en) * 2014-06-11 2017-05-24 汉高股份有限及两合公司 Hair care product and process for hair caring

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
周为群等: "《现代生活与化学》", 31 May 2016 *

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Application publication date: 20180123