CN1076098A - Information detector for blood circulation dynamics - Google Patents
Information detector for blood circulation dynamics Download PDFInfo
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- CN1076098A CN1076098A CN 92109445 CN92109445A CN1076098A CN 1076098 A CN1076098 A CN 1076098A CN 92109445 CN92109445 CN 92109445 CN 92109445 A CN92109445 A CN 92109445A CN 1076098 A CN1076098 A CN 1076098A
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Abstract
The present invention is a kind of information detector for blood circulation dynamics of the ES parameter algorithm based on the state-space model of setting up the blood of human body blood circulation with state space method, comprise the simulation amplifier unit, A/D converter, computer and with the printing and the straight line record device of computer adapted, also be provided with volume---pressure transducer by band set pressure governor motion, wrist holder and " information receiving parts that the type support is formed; ES parameter algorithm assembly and set pressure are demarcated assembly; reach the performance requirement of reception information high fidelity (Hi-Fi), the control test as a result of parameter report; zoopery and clinical verification show it is accurately and reliably.
Description
The invention belongs to Cardiovascular system disorder medical diagnosis and research utensil, further belong to a kind of AT detection blood circulation kinetic parameter and change, for clinical medicine provides the information detector for blood circulation dynamics of science diagnosis with research.
The inventor took the lead in carrying out the research of " blood circulation dynamics arteries and veins figure detection technique and pulse instrument " at home from 1972, comprise rationale, detection technique and instrument, three aspects of clinical practice checking.Wherein the parameter algorithm that relates to of fundamental research is through three phases, the SS parameter algorithm that proposed in promptly 1977, the EZ parameter algorithm that proposed in 1980, the ES parameter algorithm that proposed in 1986.SS and EZ parameter algorithm are in that in industry portion is fully open a few years ago, and the ES parameter algorithm is just to disclose for the first time in patent application of the present invention.Existing several information detector for blood circulation dynamics title differs, as " vascular function diagnostic apparatus ", the parameter algorithm of the employings such as " arteries and veins figure hematodinamics computer monitoring devices " of " left, right heart function check and analysis instrument " and CN87211253U bulletin all rests on SS parameter algorithm or EZ parameter algorithm stage, it is low that ubiquity precision, the graphical information distortion, can't discern and poor repeatability ARR figure, problems such as the concordance difference of each instrument performance, its reason is: the SS parameter algorithm is as detected information with the radial artery pulse ripple, Arterial system is considered as elastic cavity, ignored physiological property, can not solve heart, the neural reflex adjusting of blood vessel and the mathematical description of control, have many assumed conditionses, so theoretical error is too big; And the EZ parameter algorithm is under dissect physiology condition and physical geometry are laid equal stress on prerequisite, and the mathematical model that rebulids system is promptly set up a kind of parameter algorithm on the basis of hypothesis earlier.It has had obvious progress than SS parameter algorithm, but still has some problems: the parameter result who has meets clinical trend, but precision is undesirable, and as cardiac output and the contrast of electromagnetism blood-pressure meters testing result, related system is 0.8; The parameter that has is wrong, as ejection fraction etc.
The objective of the invention is defective, propose a kind of information detector for blood circulation dynamics that adopts the ES parameter algorithm at above-mentioned SS, EZ parameter algorithm.
The ES parameter algorithm is based on set up blood of human body blood circulation state-space model with state space method.Each unitary state-space expression of system is through curve match correlation analysis, and correlation coefficient is all more than 0.99, and therefore, its precision is high and reliable.The present invention is solidificated in custom-designed encryption device by constituting ES parameter algorithm parts, as core component of the present invention with the ES parameter algorithm.Simultaneously, the present invention also appropriate design information receiving parts, it comprises and has pick off, ┍ shape support and the wrist holder that set pressure is regulated calibrating device.This pick off is distinguished in existing sensors, can take the pressure of vascular pulsation and the information of volume-variation according to the determined set pressure condition of the concrete condition of different human body, analyzes the blood circulation dynamics parameter, draws correct reproducible results.Also designed set pressure and demarcated assembly, made set pressure be in appropriate state by adjusting the set pressure governor motion, so that detect.
To demarcate assembly and common simulation amplifier unit, A/D converter, computer and form one by information receiving parts, ES parameter algorithm assembly, set pressure that the pick off that has the set pressure governor motion and ┍ type support and wrist holder are formed, promptly constitute information detector for blood circulation dynamics of the present invention with the printing and the straight line record device of computer adapted.Take the information of arterial pulse wave without distortion by information receiving parts, by by A/D converter voltage being converted to digital quantity again behind the simulation amplifier unit, and move: image data, identification, value calculation of parameter by parameter algorithm assembly operating computer, parameter is declared knowledge, show and output, comprise that tracing figure and print parameters result of calculation and parameter declares the knowledge result, promptly provides blood circulation dynamics calculation of parameter result.
Information receiving parts of the present invention is by the volume-pressure transducer that has set pressure calibration adjustment mechanism, and wrist holder and ┍ shape support are formed.
The information that volume-pressure transducer is taked is that the vessel cross-sections product is a pressure with power, has limited the length of being examined vessel segment during owing to actual detected, therefore can be considered as capacity of blood vessel-pressure transducer.Its function is that the power with arteriopalmus is converted to pulse voltage signal, also set pressure is converted to the level line of DC voltage, gets rid of to disturb by the locking spring-like bolster in the set pressure governor motion to make dynamo-electric conversion that distortion not take place.
The core of volume-pressure transducer is to place a dynamo-electric converter that is provided with in the rectangle tubular shell of vertical tag line.This changer is made up of beryllium bronze band material and monocrystalline silicon membrane.Adopt the lithography plane diffusion technique to make 4 resistance and constitute Wheatstone bridge.The beryllium bronze band material is
The v notch v shape can make the deformation that its produces like this, is decided by the pressure and the long-pending size of vessel cross-sections of blood vessel, requires that it is wide, thick, long data guarantees that the fixed frequency of changer is more than 200HZ.The band material of last horizontal segment is fixed on the housing pedestal, and the film formed electric bridge of monocrystal silicon is posted on the surface.When band material stress and deformation, electric bridge resistance respective change, thereby output voltage signal, the band material of following horizontal segment posts rectangle dish shape macromolecule mantle, and face slightly protrudes from housing lower port plane, cause the pressure waveform distortion to guarantee that blood vessel is unlikely because of the stiff case compressing produces deformation under certain set pressure, also guarantee the film surface stress state that is evenly distributed, wave distortion does not take place in the rolling that certainly exists during the reason vascular pulsation under the mantle stress state of uneven distribution.
The set pressure calibration adjustment mechanism of pick off is made up of shell trip, locking spring, protective cover with cover, knob and carriage release lever.The shell trip places governor motion and pick off in it, by the trip that is positioned at right screw governor motion and pick off is fixed on the ┌ shape support, and it has 360 ° of mobilitys of horizontal plane, to guarantee that center sensor is over against the tremulous pulse axis; Locking spring makes knob be adjacent to shell, prevents that the molectron that knob, carriage release lever and dynamo-electric converter constitute from producing interference because of the quality action of gravity moves up and down with arteriopalmus; Place locking spring in the protective cover with cover, square opening in it cooperates with carriage release lever lower end square column, place on the arterial with the crossing at right angle state with the beryllium bronze band material that guarantees dynamo-electric converter, when quitting work, by knob dynamo-electric converter is pushed in the protective cover, protective cover on the bottom end cover can be protected dynamo-electric converter effectively; Knob promotes carriage release lever by screw thread and moves up and down, to regulate set pressure; The carriage release lever epimere is a spiral cylinder, and with the supporting adjusting precompression of knob, hypomere is a square column, cooperates with square opening in the protective cover, rotates to guarantee that pick off is unlikely, makes beryllium bronze band material and arterial axis keep vertical, satisfies necessary geometrical condition.Carriage release lever is a hollow structure, and hollow space is a conduit, causes disconnection fault with the unlikely twisting of protection dynamo-electric converter input and output lead.
Wrist holder in the information receiving parts, its upper surface shape are pressed the profiling of human body carpal joint and are made.The carpal joint curved surface is 40 ° for the phalanges of hyperbola curve extension to metacarpophalangeal joints, angle, and plane and base plane that chi is scratched direction are 50 ° of angles.Forearm and palm are fixed in the wrist holder with fixing band by fixing card, carpal joint and forearm are fixed under the suitable geometrical condition detect.
The crossbeam of ┍ shape support cooperates by the screw on the trip of holding screw and set pressure governor motion pick off is fixed on ┍ shape support, its straight beam can be for the truss of collapsing length with one, regulate straight beam length with lifting ┍ shape support, can coarse adjustment pick off mantle near the skin at tested position, crossbeam leans forward and straight beam is 80 ° of angles, to guarantee the pick off 10 ° of angles of leaning forward, with the wrist holder the bent 40 ° of angles of the metacarpal bone back of the body are combined, just can make the sensor axis heart parallel with the resultant force vector direction of tube wall stress ripple over against the intravascular pressure Reeb.
The operation principle of information receiving parts and work process:
(1) examinee is flat crouches, flat the stretching with trunk of left arm is 60 ° of angles, and the forearm carpal joint places in the wrist holder, the 3rd phalanges is fixed in the wrist holder with forearm with fixing band with fixing card, hand-held α of operator and β spiral, with pick off on the arteriopalmus point at processus styloideus radii place.Adjusting knob slowly promotes carriage release lever and moves down, till suitable set pressure level (horizontal line that shows on the display).Detect desired geometrical condition of arterial pulse wave and mechanical condition this moment, just remains in the constant standard compliant state.
(2) adjusting of set pressure is demarcated: when regulating the pick off knob, carriage release lever makes horizontal segment under the epipial beryllium bronze band material of dynamo-electric converter afford the effect of arterial pulse power accordingly, also afford simultaneously skin and the tensile effect of sub-dermal soft tissue, last horizontal segment band material generation deformation, bridge resistance changes thereupon, output voltage signal, what arteriopalmus was exported by dynamo-electric converter is pulse voltage signal, and it is the skew of DC voltage that skin and soft tissue tension act on the output that dynamo-electric converter produces.This output voltage is by the simulation amplifier unit, under situation than low gain, export to A/D converter, enter calculator memory, and on display screen, regularly show, when carriage release lever moves down into suitable degree, when the output voltage signal baseline has reached by the set pressure display line level of parameter algorithm device normalization, regulate the set pressure operation and stop.When keyboard input detected instruction, the computer original program just started corresponding gain analog switch, and the skew of the DC voltage that causes of compensation set pressure, made baseline return to zero-bit.
Set pressure of the present invention is demarcated assembly and is made of with solidifying in program module wherein programmable amplifier.Be connected with computer by A/D converter, the examinee's of keyboard input situations such as sex, age, height, body weight and blood pressure during according to detection, the calibration line that on display screen, shows set pressure automatically, when adjusting the set pressure governor motion, the pick off pressurized produces variation, when the skew line reaches calibration line, show that set pressure is in appropriate state.
ES parameter algorithm assembly of the present invention, comprise the Figure recognition obtaining value method, the ES parameter algorithm, the parameter situation is declared knowledge, by calculating integrated circuit, programmable read-only memory EPROMGALL etc. constitute encryption self-destruction assembly, and combine the change bus with main control computer, and main control computer chip spray glue is covered with anti-copy.It utilizes the non-reproduction of programmable gate array, and a password is set in programmable gate array, prevents the simple copy to software program.The blood circulation dynamics parameter that the ES parameter algorithm is reported is as follows:
(1) left heart function
1, pressure and modulus
(1) spray blood pressure power (EBP) (2) diastasis pressure (LVDP)
(3) cardiac muscle stress modulus (MIM)
2, capacity, flow
(1) heartbeat blood volume (SV) (2) cardiac output (CO) (3) amount diastasis (LDV) (4) ejection fractions (EF)
3, merit and energy
(1) left chamber merit (LVW) (2) cardiac energy transformation constant (MEC) (3) left chamber mechanical efficiency (LME)
4, myocardial contractility
(1) negative variable force coefficient (MNC) (3) heart rate (HR) of myocardium variable force coefficient (MIC) (2) cardiac muscle
5, myocardium blood oxygen relation between supply and demand
(1) myocardial oxygen consumption (MVO) (2) myocardial ischemia thresholding (MIT)
(2) vascular system kinetic parameter
1, pressure
(1) tremulous pulse average shrinkage pressure (SMP) (2) tremulous pulse AvDP power (DMP) (3) tremulous pulse average pressure (AMP) (4) central venous pressure (CVP)
2, modulus and impedance
(1) aorta elasticity modulus (OM) (2) medium-sized artery elastic modelling quantity (MAM) (3) small artery elasticity modulus (AOM) (4) system's total impedance (SSR) (5) ejection impedance (JR)
3, transport constant
(1) system transports constant (STR) (2) arterial pulse stream and transports constant (PTC) (3) venous return coefficient (VRK)
4, capacity and cardiac index
(1) effective circulation volume (ECV) (2) cardiac index (CI)
(3) reflexive regulatory function
(1) the sympathetic feedback factor of integrated reflection coefficient (SEC) (2) parasympathetic feedback factor (VFC) (3) (SFC)
The ES parameter algorithm is reported out 32 blood circulation dynamics parameters altogether, and this content of parameter is different with the result of SS, EZ parameter algorithm.
Effect of the present invention is:
(1) reaches the performance requirement of reception information high fidelity (Hi-Fi).
Owing to the construction features of pick off, can obtain the information of pressure and vessel segment volume-variation-Li simultaneously, can satisfy the requirement of setting up parameter algorithm; Because geometrical condition, the mechanical condition of sensor fixing assembly are fixed under the situation that meets the science requirement and detect, the change of having got rid of mechanics factor produces interfering signal, owing to can demarcate set pressure exactly and amplifier can remain in 10 hertz band, non-linear distortion degree＜0.2%, and be provided with 50 hertz lowpass digital filter; Because compensating circuit is proofreaied and correct transducer sensitivity, programmable amplifier is provided with the analog gain switch of different class, guarantee that output voltage is between the 3-4.5 volt, make the discrete sampling error reduce to Min., and can directly converse pulse wave fluctuation pressure truthful data according to gain, avoid the water argyraemia to press instrumentation to decide pressure value, subtract the pulse pressure that diastolic pressure is calculated with systolic pressure, demarcate the peak value of pulse wave fluctuation pressure, the error of being brought and mercurial sphygmomanometer method error component is more.Therefore detect the result of complete machine performance with reference signal generator, the distortion factor＜1% carries out the coefficient of variation as a result＜2% of repeated experiment.
(2), the result of parameter report accurately and reliably.
Because instrument design has guaranteed the message amount fidelity height of the arteriopalmus wave power got; Owing to guaranteed that identification is correct automatically to graphic feature point; Because the blood circulation state space equation group of setting up is through curve match correlation analysis, fitting correlation coefficient all reaches more than 0.99, has confirmed the reliability of mathematical model; The ES parametric method theoretical error of Jian Liing is little on this basis, therefore to the result of this instrument detecting blood circulation kinetic parameter report through control test, zoopery and clinical verification show it is accurately and reliably.The result that several main parameters is carried out control test is exemplified below:
1, cardiac output testing result:
This instrument and FICKShi blood gas analysis method contrast r=0.792, with thermodilution method contrast r=0.89, with the dye dilution method contrast, r=0.89, ultrasonic doppler contrast r=0.92, electromagnetism blood flow meter contrast r=0.95 is P＜0.001.
2, left ventricle spray blood pressure power testing result.
This instrument and left chamber tube method contrast r=0.96(P＜0.001)
3, central venous pressure testing result
This instrument and right heart catheter contrast r=0.913(P＜0.001)
This instrument contrasts r=0.83(P＜0.01 with the method that container is directly surveyed blood drawing blood-letting capacity)
4, effective this instrument of circulation volume testing result and container are directly surveyed method contrast r=0.83(P＜0.01 of blood drawing blood-letting capacity)
5, coronary ischemia thresholding testing result
The contrast of this instrument and selectivity pulse prefixing contrast, coincidence rate is 93%(N=661), with animal arteria coronaria chokes experiment contrast coincidence rate be 97%(N=127).
6, ejection fraction testing result
This instrument and the quick sequence photography method contrast of ventriculography of left ventricle, normal group, light moderate coronary stenosis, severe coronary stenosis (by the selectivity pulse prefixing contrast diagnosis).Three groups of results that detect with two kinds of methods all have difference between the group of highly significant, but indifference between the result of two kinds of methods.
The present invention has the following drawings;
Fig. 1 is a composition block diagram of the present invention;
I among the figure: information receiving parts, II: simulation amplifier unit, III: A/D converter VI: computer, V: print and the straight line record device VI: ES parameter algorithm assembly.
Fig. 2 is an information receiving parts structural representation of the present invention;
Among the figure 1: have the volume-pressure transducer of set pressure adjustment structure, 2: shape support, 3: the wrist holder.
Fig. 3 is the volume-pressure transducer junction structure profile that has the set pressure adjustment structure of the present invention;
1-1 among the figure: shell trip, 1-2: locking spring, 1-3: protective cover with cover, 1-4: knob, 1-5: carriage release lever, 1-6: dynamo-electric converter.
Fig. 4 is the generalized section of the dynamo-electric converter of volume-pressure transducer;
1-6-1 among the figure: housing, 1-6-2: beryllium bronze band material, 1-6-3: macromolecule mantle.
Fig. 5 is a shape supporting structure sketch map of the present invention;
2-1 among the figure: crossbeam, 2-2 straight beam, 2-3 truss.
Fig. 6 is a wrist holder side view of the present invention;
Fig. 7 is that simulation amplifier unit of the present invention is formed block diagram.
I among the figure: information receiving parts, III: A/D converter, VII: compensation correction circuit, VIII differential amplifier, IX: programming amplifier, X: 50 hertz of lowpass digital filters, XI: analog gain switch.
Below in conjunction with embodiment and contrast accompanying drawing the invention will be further described:
The rectangle tubular shell 1-6-1 of dynamo-electric converter 1-6 that has the volume-pressure transducer 1 of set pressure governor motion in the information receiving parts I of embodiment is that internal diameter size is the copper rectangular cylinder of 10 * 8 * 10 millimeters (length * wide * height), barrel is thick to be 6 millimeters, chrome-faced.Vertical mark normal all is carved with in housing four sides central authorities.Beryllium bronze band material 1-6-2 is wide to be 4 millimeters, thick is 0.3 millimeter, be bent into Contraband v notch v shape, two place's bent angles all are 90 °, go up 8 millimeters of horizontal segment lengths, 3 millimeters of vertical segment lengths, horizontal segment length is 7 millimeters down, posts 10 * 8 * 4 millimeters rectangle dish shape macromolecule mantle 1-6-3 on it, and protrudes from 0.8 millimeter on housing lower port plane, the fixed frequency of changer is 200 hertz, and sensitivity is 1 microvolt/millimetres of mercury.
The information receiving parts II of embodiment is the analog amplify circuit of band compensation correction circuit VII.Compensation correction circuit VII adopts anti-interference the connection with pick off, uses constant current source; The set pressure zero adjusting circuit, after the good set pressure of calibration adjustment, the dc offset voltage of regulating sensor bridge output returns zero line; The sensitivity of pick off output is that certain error is arranged, and the electric signal of this circuit adjustment electricity output is the voltage that the pressure of 1 millimeter post produces 1 microvolt.
Analog amplify circuit is by the differential amplifier VIII, and programmable amplifier IX and 50 hertz of lowpass digital filter X are formed.Because the fundamental frequency of pulse wave is about 1 hertz, its main harmonic wave deal is in 10 hertz, 20 hertz harmonic wave is 0.085% with the ratio of first-harmonic mould, therefore, this Amplifier Design keeps favorable linearity in 10 hertz band, non-linear true degree＜0.2%, and its common mode rejection ratio (CMRR) is more than 100 decibels, ripple voltage is suppressed at below 20 millivolts, and is strong to 50 hertz capacity of resisting disturbance.
Embodiment adopts the A/D converter III of 8 bits, aanalogvoltage output must be in the scope of 0-+5 volt, human body is under pathologic condition, fluctuation pressure can be from several millimetress of mercury to 200 millimetress of mercury, if aanalogvoltage was exported low, then discrete sampling time institute this error of taking a sample is too big, excessive then being cut put down, therefore, utilize the programmable amplifier IX that the analog gain switch XI of different gains class is set, the aanalogvoltage that makes output is write down the gain multiple between the 3-4.5 volt, the computer IV can directly converse the quantity of information of the power of radial artery pulse ripple by the gain multiple from pulse voltage.Avoid pressure value, demarcate pulse wave pressure, the error of being brought by the mercurial sphygmomanometer measurement.
Computer system comprises main control computer IV and printing and straight line record device V.The main control computer IV can be of portable form, and, shows with LCDs, with P40 drawing apparatus line drawing formula output character and figure as main control computer with Inter 8098 accurate 16 singlechip chips; Also can be desktop, with PC-XT type computer, this machine also has other function concurrently.
The source program of embodiment computer IV is a modular structure, removes the necessary initialization boot of general operation, outside Keyboard Control program and the output program, also has and adopts the similar checkout gear of EZ parameter algorithm and SS parameter algorithm not have and special functional module.
(1) portable in real time the demonstration: to adapt to the custom that the medical worker sees the recorder output pattern, adopt portable graphic display method on display, this practicality for ARR figure is observed and is worth.
(2) graph curve briliancy differential shows: arteries and veins figure is that the phasic property curved section is formed by connecting during by cardiac cycle, and different curved sections have different curvature; The sphygmogram characteristic point is the junction point of two curved sections or the initial point of curve.For the ease of the right and wrong of the automatic recognition feature point of medical worker's real-time monitoring instrument, the thickness of arteries and veins figure curve lines is decided with this amount of curvature.Be the big person of rate of change, lines are thin.Show the junction point of the curved section of two different curvature like this, can come into plain view, guarantee the accurate of identification.
(3) the identification value program module of ARR arterial tracing: for ARR some diseases such as atrium fibrillation, premature beat, the lopsided arterial tracing that atrioventricular dissociation etc. produced.
(4) special arteries and veins figure establishment has deal with data program respectively to arrhythmia and pulsus alternans etc.
(5) also have the parameter result to declare the knowledge program and cardiovascular function is declared the knowledge program.
The ES parameter algorithm assembly VI of embodiment is actually a software program, resides in the main control computer IV, for preventing that duplicating this program is provided with a password in programmable gate array GAL, connects through I/O interface and ES parameter algorithm assembly VI.In each stage of program operation, give GAL by I/O interface output different pieces of information, receive return information from GAL again, the main control computer IV, check its information, if errorless, program is normally carried out, if information errors, then program can be taked the measure of different brackets, or stops data acquisition, or stops calculation of parameter, or the shut down procedure operation, or destroy original program.
Claims (2)
1, a kind of comprise simulation amplifier unit, A/D converter, computer and with the printing of computer adapted and the information detector for blood circulation dynamics of straight line record device, it is characterized in that:
1.1 be provided with by the volume that has set pressure calibration adjustment mechanism--pressure transducer, wrist holder and the " information receiving parts of shape support; the core of volume-pressure transducer is to place a dynamo-electric converter that is provided with in the rectangle tubular shell of vertical tag line; this changer is made up of beryllium bronze band material and monocrystalline silicon membrane; adopt the lithography plane diffusion technique to make 4 resistance formation Wheatstone bridges; the beryllium bronze band material is a Contraband v notch v shape; upward the band material of horizontal segment is fixed on the housing pedestal, the film formed electric bridge of monocrystal silicon is posted on the surface, the band material of following horizontal segment posts rectangle dish shape macromolecule mantle, and face slightly protrudes from housing lower port plane, the set pressure governor motion of pick off is by the shell trip, locking spring, protective cover with cover, knob and carriage release lever are formed, the upper surface shape of wrist holder is pressed the profiling of human body carpal joint curved surface and is made, the crossbeam of T shape support leans forward and straight beam is 80 ° of angles, and straight beam can be for the truss of collapsing length with one;
1.2 be provided with ES parameter algorithm assembly, comprise the Figure recognition obtaining value method, the ES parameter algorithm, the parameter situation is declared knowledge, by calculating integrated circuit, programmable read-only memory EPROM, GALL sheet etc. constitute encrypts the self-destruction assembly, and combines the change bus with main control computer, main control computer chip spray glue is covered, a password is set in programmable array.
Demarcate assembly 1.3 be provided with set pressure, constituted with solidifying in program module wherein by programmable amplifier.
2, information detector for blood circulation dynamics according to claim 1, it is characterized in that simulating the analog amplify circuit that amplifier unit is a band compensation correction circuit, analog amplify circuit is made up of differential amplifier, programmable amplifier and 50 hertz of lowpass digital filters.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 92109445 CN1076098A (en) | 1992-09-03 | 1992-09-03 | Information detector for blood circulation dynamics |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 92109445 CN1076098A (en) | 1992-09-03 | 1992-09-03 | Information detector for blood circulation dynamics |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100344257C (en) * | 2004-06-17 | 2007-10-24 | 肖行贯 | Cardiovascular dynamics checking checkup method |
| CN103190893A (en) * | 2012-01-04 | 2013-07-10 | 深圳市景新浩科技有限公司 | Method and system for calibrating parameters of blood-pressure meter |
| CN106063734A (en) * | 2015-04-24 | 2016-11-02 | 西门子股份公司 | For creating the method for stent graft and calculating and print unit |
| CN109310346A (en) * | 2016-06-03 | 2019-02-05 | 阿特里亚创新私人有限公司 | Equipment of the detection with reliably obtaining for pulse characteristics |
-
1992
- 1992-09-03 CN CN 92109445 patent/CN1076098A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100344257C (en) * | 2004-06-17 | 2007-10-24 | 肖行贯 | Cardiovascular dynamics checking checkup method |
| CN103190893A (en) * | 2012-01-04 | 2013-07-10 | 深圳市景新浩科技有限公司 | Method and system for calibrating parameters of blood-pressure meter |
| CN103190893B (en) * | 2012-01-04 | 2015-05-20 | 深圳市景新浩科技有限公司 | Method and system for calibrating parameters of blood-pressure meter |
| CN106063734A (en) * | 2015-04-24 | 2016-11-02 | 西门子股份公司 | For creating the method for stent graft and calculating and print unit |
| CN109310346A (en) * | 2016-06-03 | 2019-02-05 | 阿特里亚创新私人有限公司 | Equipment of the detection with reliably obtaining for pulse characteristics |
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