CN1163091A - Diagnosting and monitoring electrocardiograph designed based on hemodynamics - Google Patents

Diagnosting and monitoring electrocardiograph designed based on hemodynamics Download PDF

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Publication number
CN1163091A
CN1163091A CN 96104688 CN96104688A CN1163091A CN 1163091 A CN1163091 A CN 1163091A CN 96104688 CN96104688 CN 96104688 CN 96104688 A CN96104688 A CN 96104688A CN 1163091 A CN1163091 A CN 1163091A
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circuit
signal
sampling box
pulse wave
amplifier
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CN 96104688
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Chinese (zh)
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何素荣
解光亮
张洪恩
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Abstract

The said electrocardiograph has a specially designed sampling box collecting pulse wave and electrocardiogram signal synchronously and continuously, a computer system, which receives, displays, analyzes and calculates, and prints analysis report and has specially designed specialist system capable of proposing therapeutic proposal. The sampling box has special circuit, which eliminates signal crosstalk and regulates gain electrically and steplessly, and its design of optoelectronic isolation before A/D conversion results in low cost and simple structure. The present invention can obtain hemodynamics, electrocardio and pulse condition parameters fastly and at low cost, and it is used for detection and monitoring.

Description

Diagnosting and monitoring electrocardiograph designed based on hemodynamics
The invention belongs to medical Instrument field, the noinvasive triage that relates to a kind of hemodynamic parameter is surveyed monitor system.
The hemodynamic parameter of human body, be to check diagnosis of cardiovascular systemic disease and other various important evidence to the influential disease of systema cariovasculare functional, many parameters can obtain and whether accurate, to many diseases make a definite diagnosis and etiological analysis is absolutely necessary.But detect such parameter at present both at home and abroad still based on coronary angiography method, cardiac catheterization methed etc.Its major defect is: 1, wound is arranged, and patient is painful big; 2, get parms less; 3, suitable disease is few; 4, expense height; 5, detect and to waste time and energy, be difficult to be applied to critical patient's monitoring etc.From 84 years this patent first inventors what plain flourish release China's first " microcomputer cardiac function detector " after, though domestic have manufacturer production to cross several similar detectors, as pulse instrument (also being referred to as cardiograph), available non-invasive methods obtains some hemodynamic parameters, but still have many defectives, as function singleness, it is few to get parms, no specialist system auxiliary diagnosis and treatment etc.
The objective of the invention is: 1, make the patient that need do the hemodynamic parameter detection become noinvasive by there being wound to detect as much as possible, eliminate patient's misery; 2, reduce testing cost, make the hemodynamics inspection become a kind of routine examination, be applied to all indications; 3, when gathering arteries and veins figure, increase electrocardiogram synchronous acquisition function; Increase output, enlarge range of application; 4, make the pulse wave of collection and electrocardiogram can be continuously roll display for a long time, realize hemodynamic parameter and the synchronous monitoring function of electrocardiogram; 5, increase specialist system, provide diagnosis and treatment suggestion.
The object of the invention realizes by following design.
Feature of the present invention is to adopt newly-designedly can to gather pulse wave signal for a long time continuously synchronously and the sample circuit of electrocardiosignal, automatically controlled stepless gain adjustment circuit, crosstalk elimination circuit, first photoelectricity are isolated back A/D data converted Acquisition Circuit, show, carry out pulse wave and Electrocardiographic automatic pointing and manual the correction by computer reception and continuous rolling, calculate hemodynamic parameter, EGC parameter, pulse parameter then, show printing analysis report, 20 seconds initial data of storage and analysis report, provide the Clinics and Practices suggestion by specialist system.
Below to the technical scheme and the detailed in addition in conjunction with the accompanying drawings explanation of technical characterictic of this invention:
The present invention's (seeing Fig. 1 for details) scratches the patient pulse wave signal of tremulous pulse and adopts into sampling box 3 through high sensitivity pulse transducer 1, patient's electrocardiosignal is adopted into sampling box 3 through the line 2 that leads, by sampling box 3 finish that amplification, multichannel are selected, photoelectricity is isolated, function such as A/D conversion, data are latched, and the data application signal that the sequence circuit of sampling box 3 is produced is input in the microcomputer 4, gathered continuously and roll display on high resolution color display 5 by microcomputer 4 again.Automatically finish fixed point and calculating after stopping to gather, the result is presented on 5, result shown on 5 is by laser printer 6 output examining reports.The sampling box of above-mentioned particular design of the present invention adds the specialist system (seeing Fig. 6 for details) that is used with it, just can provide diagnostic result and treatment suggestion according to the unusual parameter from the examining report of 6 outputs.
Sampling box internal structure such as Fig. 2 that the present invention is designed.Pulse wave signal by pulse transducer 1 input is sent into multiway analog switch 2.4 and crosstalk elimination circuit 2.5 through pulse twt amplifier 2.1, automatically controlled stepless gain adjustment circuit 2.2, produce gain adjust signal, in the signal input 2.1 by output in 2.2, the amplification of control 2.1, electrocardiosignal by cardiac diagnosis lead-line 2 inputs is also sent into multiway analog switch 2.4 and crosstalk elimination circuit 2.5 through ECG signal amplifier 2.3, the output of multiway analog switch 2.4 becomes digital quantity through simulated Measurement Photoelectric Isolated Circuit 2.6 to A/D converter 2.7,2.7 output digital quantity latch by data latches 2.8, the digital quantity that latchs by interface circuit 2.11 by computer acquisition.Interface circuit 2.11 is introduced sampling box with computer power supply simultaneously, uses for each unit, floating ground of 2.1,2.2,2.3,2.4,2.5,2.6 before the A/D converter 2.7 through the float power that Switching Power Supply 2.9 produces and main frame is isolated.Clock signal from computer is input to sequential control circuit 2.10 by interface circuit 2.11, and the control signal that is produced by sequential control circuit 2.10 is coordinated the work of whole sampling box.
The crosstalk elimination circuit 2.5 that the present invention uses realizes that by multiway analog switch when a road in the computer acquisition two paths of signals, another road signal simulated the bypass of switch institute.Can realize that two paths of signals is alternately gathered and bypass under sequence circuit 2.10 controls by the connection of circuit a, b in Fig. 2.
Automatically controlled stepless gain adjustment circuit such as Fig. 3 that the present invention adopts, increasing button 3.1 and reduce the output that button 3.2 is used for changing gain adjusting circuit 3.3, deliver to the input of photoelectric isolating device 3.5 via sampling hold circuit 3.4,3.5 output links through overcoupled circuits 3.7 and pulse wave amplifier 2.1.3.6 be the gain preset circuit, this circuit is input to the gain preset signal in the photoisolator 3.5.It makes gain reach a suitable initial value rapidly when sampling box powers up.
Analogue signal photoelectric isolating circuit such as Fig. 4 that the present invention adopts, sampled signal from multiway analog switch (among Fig. 2 2.4) outfan is sent into photoisolator 4.3, photoisolator 4.4 through follower 4.1, manipulator 4.2, and photoelectric output signal is finished analog digital conversion by A/D converter 2.7 behind amplifier 4.5.
Sequence circuit such as Fig. 5 that the present invention adopts, the clock signal that is produced by clock circuit 5.1 enters sequence circuit 5.2, the signal that sequence circuit 5.2 produces enters the controlling of sampling that pulse wave, electrocardiogram controlling of sampling circuit 5.3 are finished pulse wave and ECG signal, it is stable, continuously, send data application signal to computer for a long time to enter data acquiring control circuit 5.4, finishes data acquisition by computer 4.
Specialist system logic diagram such as Fig. 6 that the present invention adopts, it is made of enquiry module 6.1, knowledge base maintenance module 6.2, auxiliary diagnosis treatment module 6.3.Enquiry module can the query argument definition, the possible cause of disease of range of normal value, abnormal parameters, various disease be to contents such as the function of may the influencing of parameter, relevant medicine and medication guides.The knowledge base maintenance module can be to the content increase and decrease and modification in each storehouse.Auxiliary diagnosis and treatment module can be according to the unusual parameters of patient, and promptly the unusual parameter to various disease provides diagnosis and treatment suggestion.The detailed logic execution of this specialist system is asked for an interview shown in Figure 6.
In sum, major advantage of the present invention is: 1 not only can be used for the inspection of hemodynamic parameter and EGC parameter, also can be used for critical patient's hemodynamics and cardiac monitoring; 2 can export 53 of hemodynamic parameters simultaneously, 18 of electrocardiogram parameters, and 6 of Chinese medicine pulse data can be made a definite diagnosis more disease with the present invention.Can be Chinese medicine pulse research objective indicator is provided.3 specialist systems help to make diagnosis and provide the treatment suggestion, and the doctor is raised the professional level.4 circuit refines are reliable, have overcome inevitably wearing and tearing or the switch stepping problem such as discontinuous of regulating of potentiometer life-time service.The initial datas of 5 storages and report can for the consultation of doctors, clinical research with, can repeatedly have access to and print the accumulation of realization case data.In a word, because it is easy to use, feature richness, and the noinvasive that detects, low cost, accurately, will be widely used clinically, improves the social benefit and the economic benefit of hospital greatly, improve the people's health level, for the prosperity of country is made contributions.
Description of drawings: Fig. 1 overall structure figure
1. pulse wave sensor
2. cardiac diagnosis lead-line
3. sampling box
4. main frame
5. color display
6. laser printer Fig. 2 sampling box circuit block diagram
2.1. pulse wave signal amplifier
2.2. automatically controlled stepless gain adjusting circuit
2.3. ECG signal amplifier
2.4. multiway analog switch
2.5. crosstalk elimination circuit
2.6. simulated Measurement Photoelectric Isolated Circuit
2.7.A/D transducer
2.8. data latches
2.9. Switching Power Supply
2.10. sequential control circuit
2.11. the automatically controlled stepless gain adjusting circuit of interface circuit Fig. 3
3.1. increasing button
3.2. reduce button
3.3. gain adjusting circuit
3.4. sampling hold circuit
3.5. photoelectric isolating device
3.6. gain preset circuit
3.7. coupling circuit
2.1. pulse wave amplifier Fig. 4 simulated Measurement Photoelectric Isolated Circuit
4.1. follower
4.2. manipulator
4.3. photoisolator 1
4.4. photoisolator 2
4.5. amplifier
4.6.A/D transducer Fig. 5 sequential control circuit
5.1. clock circuit
5.2. sequence circuit
5.3. pulse wave, electrocardiogram controlling of sampling circuit
5.4. data acquiring control circuit Fig. 6 specialist system logic diagram
6.1. enquiry module
6.2. knowledge base maintenance module
6.3. auxiliary diagnosis and treatment module
The present invention's embodiment such as Fig. 1 are to shown in Figure 6.The specific implementation process is:
Place the patient to scratch the tremulous pulse place pulse wave sensor and obtain pulse wave signal, cardiac diagnosis lead-line is led to connect by C.C5 obtain ECG signal.The signal that obtains is input in the sampling box, and via delivering to the multiway analog switch input behind the amplifier separately, under the control of sequence circuit, pulse wave signal and ECG signal alternately appear at outfan.Again through arriving A/D converter behind the photoelectric isolating circuit, its output is latched device latch after, under the control of sequence circuit, interface circuit, deliver in the computer.
Computer promptly enters data continuous acquisition state after startup, pulse wave and the electrocardiogram (ECG) data that collects is converted to graph data, makes pulse wave and electrocardiogram right-to-left continuous rolling on screen.This state can continue arbitrarily long-time, can suspend rolling at any time, fixes a point, date processing, report output, data storage, and then gets back to and gather and rolling condition.So it both can be used for the inspection (only carrying out date processing No. a time) of hemodynamic parameter and EGC parameter prevailingly, also can be in long-time deal with data repeatedly, the output result carries out the monitoring of hemodynamic parameter and EGC parameter to the critical patient.
The present invention's embodiment is when the beginning date processing, eject a size, choice box that the position is adjustable, after selecting a complete distortionless pulse wave, computer is amplified to full screen with it and shows, and finish the labelling of automatic pointing and point, enter artificial fixed point state, calculate, report that demonstration, result print, data storage after by the operator unfavorable point being revised.Arrive this, the doctor can make diagnosis according to report and patient's clinical symptoms, implements treatment.Also can enter in the specialist system, under the help of specialist system, diagnose and treat.
The present invention's embodiment can various modes show and the printing analysis report that the pattern of wherein guarding is only exported 12 key parameters, is highly suitable for critical patient's rescue.
The present invention's embodiment major parameter is as follows:
Pulse transducer:
Model PT14M3 range 40Kpa
Full scale output 83mv/5v is non-linear<0.1%FS
Sluggishness<0.1%FS zero-bit imbalance 3mv
Overvoltage protection 1Mpa
Sampling box:
Pulse wave signal amplifier gain 30--1500 is doubly adjustable continuously
1000 times of ECG signal amplifier gains
Sample rate 860 times/second
12 of A/D converter precision
Computer system:
Main frame 486 * 66
Display 1024 (768 colour display screens
Printer HP5L type laser printer
The present invention's embodiment output parameter is:
One, hemodynamic parameter is 53, wherein:
7 of coronary circulation parameters:
The essential impedance of CMR arteria coronaria, MOC myocardial oxygen consumption, MEM myocardial volume elastic modelling quantity, MER mechanical efficiency ratio, CPRM arteria coronaria periphery regulative mechanism, MNB cardiac muscle need blood volume, the static Yang Shi elastic modelling quantity of ASE tremulous pulse.
7 of volume, flows:
SV whenever fight cardiac output, CO per minute cardiac output, CI cardiac index, the per minute cardiac output of unit bodies surface area, EF ejection fraction, LESV left side chamber end systolic volume, the effective circulation volume of ECV, TBV total blood volume.
7 of feedback factors:
The sympathetic feedback factor of SFC, VFC fan walk feedback factor, the FES ejection fraction and the feedback factor that sprays between blood volume between feedback factor, FEL left side chamber transport coefficient and jet pressure between feedback factor, FSA tremulous pulse transport coefficient and average systolic between feedback factor, the comprehensive feedback factor of SRC, FCA tremulous pulse transport coefficient and heartbeat amount.
8 of cardiac muscle power energy:
Chamber, LTPF left side master cylinder power, the effective pump power in LEP chamber, a left side, CTP heart general power, LVEP left ventricle effective power, HR heart rate, chamber, LEER left side effective energy output rating, MEC cardiac energy transformation ratio, STI systolic time interval.
4 of microcirculation parameters:
ATB blood mean residence time, BAT blood flow update time, BSD blood flow smoothness, BAR blood flow turnover rate.
4 of transport coefficients:
STC system transport coefficient, chamber, a LTC left side belong to fortune coefficient, TAT tremulous pulse terminal transport coefficient, VRC venous return coefficient.
4 of cardiac cycle parameters:
PEP PEP, LVET left ventricular ejection time, EVDP isovolumic contraction period, chamber, LVFP left side filling phase.
5 of pressure datas:
SMP average systolic, DMP AvDP, MAP mean arterial pressure, the average pulse pressure of MPP, EP jet pressure.
2 of preload parameters:
Chamber, LEDV left side end-diastolic volume, chamber, LEDP left side diastasis pressure.
2 of room, left side parameters:
AV LA vol, room, LAFP left side filling pressure.
3 of impedance parameters:
TPR total impedance, the impedance of LER left side chamber spray blood, the impedance of MCR microcirculation.
18 of two electrocardiogram measurement data:
The width of P, Q, R, S, T ripple and height
The QRS burst width, R-R interval, P-Q interval, Q-T interval, p-q section time, s-t section time, s-t section height; E-C coupling connection (time difference that ECG R wave is ordered to pulse wave b1).
6 of three Chinese medicine pulse objective indicator data: P1, P2 ... P6.
Can reflect situations such as the puckery and tensile string of sering of the cunning of length, pulse wave of width, the pulse crest of slow number, the sering of pulse frequency is soft.

Claims (5)

1, a kind of Diagnosting and monitoring electrocardiograph designed based on hemodynamics, constitute by pulse transducer, pulse wave signal amplifier, A/D converter, Acquisition Circuit, computer, printer, data handling system and sampling apparatus, it is characterized in that having the sampling box of particular design:
1.1, sampling box is by pulse wave signal amplifier, ECG signal amplifier, multiway analog switch and can gather the pulse wave signal and the crosstalk elimination circuit of electrocardiosignal and the sequential control circuit of automatically controlled electrodeless gain adjustment circuit, A/D converter, data latches, Switching Power Supply and the whole sampling box work of simulated Measurement Photoelectric Isolated Circuit, interface circuit and coordination for a long time continuously synchronously and form;
1.2, each ingredient of sampling box to be coupled to each other relation as follows:
Pulse wave signal by pulse transducer 1 input is sent into multiway analog switch 2.4 and crosstalk elimination circuit 2.5 through pulse twt amplifier 2.1, amplification by output signal input 2.1 controls 2.1 in 2.2, electrocardiosignal by the cardiac diagnosis lead-line input is sent into multiway analog switch 2.4 and crosstalk elimination circuit 2.5 through electrocardiogram amplifier 2.3, connect simulated Measurement Photoelectric Isolated Circuit 2.6 in 2.4 back, thereafter connecting makes signal become the A/D converter 2.7 of data, enter data latches 2.8 again, the digital quantity that latchs by interface circuit 2.11 by computer acquisition, clock signal from computer is input to the work that sequential control circuit 2.10 is coordinated whole sampling box through interface circuit 2.11 again, the simultaneous computer power supply enters the float power that Switching Power Supply 2.9 produces and main frame is isolated through interface circuit 2.11 and gives each unit power supply, in the computer acquisition two paths of signals its for the moment, another road signal can be by a by the multiway analog switch bypass, the b circuit connects to be realized.
2, a kind of Diagnosting and monitoring electrocardiograph designed based on hemodynamics, the automatically controlled stepless gain adjustment circuit that it is characterized in that in the sampling box being adopted, be by increasing button 3.1 and the output signal that reduces button 3.2 change gain adjusting circuits 3.3, deliver to the input of photoelectric isolating device 3.5 via sampling hold circuit 3.4, linked through overcoupled circuits 3.7 and pulse wave amplifier 2.1 by 3.5 outputs, adopting simultaneously can be with the gain preset circuit 3.6 of gain preset signal input photoelectric isolating device 3.5 again.
3, a kind of Diagnosting and monitoring electrocardiograph designed based on hemodynamics, the analogue signal photoelectric isolating circuit that it is characterized in that in the sampling box being adopted, it is that the sampled signal from the multiway analog switch outfan is sent into photoisolator 4.3 and 4.4 through follower 4.1, manipulator 4.2, makes photoelectric output signal carry out analog digital conversion by A/D converter 2.7 behind amplifier 4.5.
4, a kind of Diagnosting and monitoring electrocardiograph designed based on hemodynamics, the sequence circuit that it is characterized in that in the sampling box being adopted, be to produce signal by clock circuit 5.1 to enter sequence circuit 5.2, enter control circuit 5.3 again and finish the controlling of sampling of pulse wave and ECG signal, then by stable, continuously, the acquisition control circuit 5.4 that sends data to computer for a long time finishes.
5, a kind of Diagnosting and monitoring electrocardiograph designed based on hemodynamics as claimed in claim 1 has specialist system matching used with it, it is characterized in that this system is made up of enquiry module, knowledge base maintenance module, auxiliary diagnosis treatment module, this specialist system is to realize following technical characterictic by above-mentioned three main modular coupled computers, display and printers:
5.1, by the described specialist system of claim 5, it is characterized in that enquiry module can inquire about rapidly to may the influencing of parameter, about contents such as the function of medicine and medication guides accurately to possible the cause of disease of parameter-definition, range of normal value, abnormal parameters, various disease;
5.2, by the described specialist system of claim 5, it is characterized in that the knowledge base maintenance module can finish operations such as the increase of each storehouse content, deletion, modification, ordering.Its implementation as shown in Figure 6;
5.3, by the described specialist system of claim 5, it is characterized in that auxiliary diagnosis treatment module can show the unusual parameter of patient, and do necessary additions and deletions by the doctor, provide the possible paathogenic factor of patient's unusual parameter then, the doctor carries out multinomial selection in conjunction with clinical symptoms again, provides diagnosis and medication suggestion.
CN 96104688 1996-04-22 1996-04-22 Diagnosting and monitoring electrocardiograph designed based on hemodynamics Pending CN1163091A (en)

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CN 96104688 CN1163091A (en) 1996-04-22 1996-04-22 Diagnosting and monitoring electrocardiograph designed based on hemodynamics

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Application Number Priority Date Filing Date Title
CN 96104688 CN1163091A (en) 1996-04-22 1996-04-22 Diagnosting and monitoring electrocardiograph designed based on hemodynamics

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101972141A (en) * 2010-08-17 2011-02-16 中国科学院苏州纳米技术与纳米仿生研究所 Primary care oriented heart cerebrovascular characteristic signal real-time sensing and monitoring system
CN103049631A (en) * 2011-10-13 2013-04-17 客隆生医科技股份有限公司 Computer pulse wave diagnostic analysis device and method
CN106308837A (en) * 2015-07-10 2017-01-11 东芝医疗系统株式会社 Diagnosis bed for medical image diagnosis and medical image diagnosis device
CN107920788A (en) * 2015-08-24 2018-04-17 威里利生命科学有限责任公司 For photoplethysmographic and the integrated-optic device of electrocardiogram
CN109452937A (en) * 2018-12-26 2019-03-12 中国计量科学研究院 Multifunctional human electro physiology simulator and control method
CN111939031A (en) * 2020-08-19 2020-11-17 郑州铁路职业技术学院 Special nursing physiotherapy pad of cardiovascular internal medicine

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101972141A (en) * 2010-08-17 2011-02-16 中国科学院苏州纳米技术与纳米仿生研究所 Primary care oriented heart cerebrovascular characteristic signal real-time sensing and monitoring system
CN101972141B (en) * 2010-08-17 2012-07-04 中国科学院苏州纳米技术与纳米仿生研究所 Primary care oriented heart cerebrovascular characteristic signal real-time sensing and monitoring system
CN103049631A (en) * 2011-10-13 2013-04-17 客隆生医科技股份有限公司 Computer pulse wave diagnostic analysis device and method
CN106308837A (en) * 2015-07-10 2017-01-11 东芝医疗系统株式会社 Diagnosis bed for medical image diagnosis and medical image diagnosis device
CN106308837B (en) * 2015-07-10 2018-05-04 东芝医疗系统株式会社 The diagnostic bed and medical image diagnosis device of medical image diagnosis
CN107920788A (en) * 2015-08-24 2018-04-17 威里利生命科学有限责任公司 For photoplethysmographic and the integrated-optic device of electrocardiogram
CN109452937A (en) * 2018-12-26 2019-03-12 中国计量科学研究院 Multifunctional human electro physiology simulator and control method
CN111939031A (en) * 2020-08-19 2020-11-17 郑州铁路职业技术学院 Special nursing physiotherapy pad of cardiovascular internal medicine

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