CN107595857A - 用于眼部疾病和病症的组合物和治疗 - Google Patents

用于眼部疾病和病症的组合物和治疗 Download PDF

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Publication number
CN107595857A
CN107595857A CN201710063950.2A CN201710063950A CN107595857A CN 107595857 A CN107595857 A CN 107595857A CN 201710063950 A CN201710063950 A CN 201710063950A CN 107595857 A CN107595857 A CN 107595857A
Authority
CN
China
Prior art keywords
progesterone
use according
patient
composition
effective amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710063950.2A
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English (en)
Chinese (zh)
Inventor
张葳葳
肯尼斯·索耶
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glia LLC
Original Assignee
Glia LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glia LLC filed Critical Glia LLC
Publication of CN107595857A publication Critical patent/CN107595857A/zh
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
CN201710063950.2A 2012-07-27 2013-07-26 用于眼部疾病和病症的组合物和治疗 Pending CN107595857A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261676530P 2012-07-27 2012-07-27
US61/676,530 2012-07-27
US201361756321P 2013-01-24 2013-01-24
US61/756,321 2013-01-24
CN201380039713.2A CN104661663A (zh) 2012-07-27 2013-07-26 用于眼部疾病和病症的组合物和治疗

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201380039713.2A Division CN104661663A (zh) 2012-07-27 2013-07-26 用于眼部疾病和病症的组合物和治疗

Publications (1)

Publication Number Publication Date
CN107595857A true CN107595857A (zh) 2018-01-19

Family

ID=49997851

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201380039713.2A Pending CN104661663A (zh) 2012-07-27 2013-07-26 用于眼部疾病和病症的组合物和治疗
CN201710063950.2A Pending CN107595857A (zh) 2012-07-27 2013-07-26 用于眼部疾病和病症的组合物和治疗

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN201380039713.2A Pending CN104661663A (zh) 2012-07-27 2013-07-26 用于眼部疾病和病症的组合物和治疗

Country Status (20)

Country Link
US (2) US20150216877A1 (enExample)
EP (1) EP2877184B1 (enExample)
JP (1) JP6209777B2 (enExample)
KR (1) KR102097663B1 (enExample)
CN (2) CN104661663A (enExample)
AU (1) AU2013295645B2 (enExample)
BR (1) BR112015001847A8 (enExample)
CA (1) CA2880027C (enExample)
DK (1) DK2877184T3 (enExample)
ES (1) ES2759781T3 (enExample)
HU (1) HUE046963T2 (enExample)
IL (1) IL236920B (enExample)
IN (1) IN2015DN00542A (enExample)
MX (1) MX362185B (enExample)
NZ (1) NZ704247A (enExample)
PL (1) PL2877184T3 (enExample)
PT (1) PT2877184T (enExample)
SM (1) SMT201900678T1 (enExample)
WO (1) WO2014018856A1 (enExample)
ZA (1) ZA201500561B (enExample)

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Publication number Priority date Publication date Assignee Title
CA2856520C (en) 2011-11-23 2021-04-06 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
AU2014239842B2 (en) 2013-03-15 2018-07-19 Glia, Llc Cranial delivery of pharmaceuticals
WO2015080758A1 (en) * 2013-11-27 2015-06-04 Al-Qahtani Ahmed H Method and composition for the treatment of moderate to severe keratoconjunctivitis sicca
AR100562A1 (es) 2014-05-22 2016-10-12 Therapeuticsmd Inc Composición farmacéutica de estradiol y progesterona para terapia de reemplazo hormonal
WO2016014419A1 (en) 2014-07-21 2016-01-28 Glia, Llc Method for treating radiotherapy-and-chemotherapy associated cognitive or emotional impairment with cannabinoids
AU2015296609A1 (en) 2014-07-29 2016-12-22 Therapeuticsmd, Inc. Transdermal cream
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
AU2017239645A1 (en) 2016-04-01 2018-10-18 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
KR101960023B1 (ko) * 2016-12-21 2019-03-20 김보경 이산화탄소 발생 장치
CA3167771A1 (en) * 2020-02-12 2021-08-19 Glia, Llc Progesterone combinations

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100016264A1 (en) * 2007-12-05 2010-01-21 Connor Charles G Treatment for dry eye using testosterone and progestagen
CN101757622A (zh) * 2008-11-28 2010-06-30 天津金耀集团有限公司 一种眼部抗炎的药物组合物

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US5102656A (en) 1983-07-29 1992-04-07 The Mennen Company Antiperspirant creams
US4937069A (en) 1985-11-15 1990-06-26 Bristol-Myers Squibb Company Anhydrous semi-solid antiperspirant suspension
US5069897A (en) 1987-10-16 1991-12-03 The Proctor & Gamble Company Antiperspirant creams
US6659985B2 (en) 2002-01-30 2003-12-09 Southern College Of Optometry Method to use transdermal administration of androgens to the adnexa of the eye
US7572780B2 (en) 2003-01-21 2009-08-11 Dimera, Incorporated Method and kit for reducing the symptoms of peripheral vascular disease
US20080132475A1 (en) 2006-12-05 2008-06-05 Charles Gerald Connor Treatment for dry eye
BRPI0819081A8 (pt) * 2007-10-08 2016-08-30 Fovea Pharmaceuticals Sa Formulação oftálmica aquosa, processo para preparar a mesma, e, método para inibir, tratar ou prevenir doenças oculares e doença ou condição relacionada, em um paciente em necessidade de tal tratamento
AU2010302350B2 (en) * 2009-10-02 2015-06-18 Journey Medical Corporation Surfactant-free water-free foamable compositions, breakable foams and gels and their uses

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100016264A1 (en) * 2007-12-05 2010-01-21 Connor Charles G Treatment for dry eye using testosterone and progestagen
CN101757622A (zh) * 2008-11-28 2010-06-30 天津金耀集团有限公司 一种眼部抗炎的药物组合物

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
杨文等主编: "《老年医学分册 下》", 31 December 2010, 吉林大学出版社 *

Also Published As

Publication number Publication date
US20150216877A1 (en) 2015-08-06
EP2877184B1 (en) 2019-09-04
PL2877184T3 (pl) 2020-04-30
MX362185B (es) 2019-01-08
BR112015001847A2 (pt) 2017-07-04
KR102097663B1 (ko) 2020-04-06
WO2014018856A1 (en) 2014-01-30
HUE046963T2 (hu) 2020-04-28
JP2015524434A (ja) 2015-08-24
BR112015001847A8 (pt) 2021-09-08
ZA201500561B (en) 2016-04-28
CA2880027C (en) 2021-12-07
NZ704247A (en) 2018-04-27
US9925201B2 (en) 2018-03-27
AU2013295645A1 (en) 2015-02-05
MX2015001250A (es) 2015-10-22
PT2877184T (pt) 2019-12-02
CN104661663A (zh) 2015-05-27
KR20150038311A (ko) 2015-04-08
AU2013295645B2 (en) 2017-08-24
HK1210968A1 (en) 2016-05-13
JP6209777B2 (ja) 2017-10-11
EP2877184A1 (en) 2015-06-03
CA2880027A1 (en) 2014-01-30
DK2877184T3 (da) 2019-12-09
ES2759781T3 (es) 2020-05-12
IL236920B (en) 2018-06-28
US20170189413A1 (en) 2017-07-06
EP2877184A4 (en) 2016-03-30
SMT201900678T1 (it) 2020-03-13
IN2015DN00542A (enExample) 2015-06-26

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Application publication date: 20180119