CN107583111A - A kind of micro- profitization processing method of catheter surface - Google Patents
A kind of micro- profitization processing method of catheter surface Download PDFInfo
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- CN107583111A CN107583111A CN201711047892.0A CN201711047892A CN107583111A CN 107583111 A CN107583111 A CN 107583111A CN 201711047892 A CN201711047892 A CN 201711047892A CN 107583111 A CN107583111 A CN 107583111A
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- profitization
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- processing method
- conduit
- catheter surface
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Abstract
The invention discloses a kind of micro- profitization processing method of catheter surface, by the strong high polymer material of the hydrophilic of medical grade, water-retaining property be made pulvis carried out in closed container atomization be suspended into it is density stabilized；By the processing of catheter proximal end surface solvent melt and dissolvedization and then as in above-mentioned closed container, making its adsorption pulvis and solidify.Conduit after this micro- profitization of the invention, can form the lubrication face as " loach " after need to only being contacted before use with water 30 seconds on the surface of its front end, greatly reduce the friction of conduit and bodily tissue.Patient's without pain during intubation.Lubricating film effect keeps lasting, difficult for drop-off.There is good biocompatibility, be not easy to cause cavity to infect.
Description
Technical field
The present invention relates to a kind of micro- profitization processing method of catheter surface.
Background technology
With the development of medical technology, medical catheter is widely used in clinic.Just it is applied to inside and outside at present
Conduit species, up to hundred kinds.General conduit is all with simple medical rubber hose.The flexible pipe system such as silicone tube and polyvinyl chloride
Into.In order to smooth in use, reduction frictional force, lubricant can be smeared in its front end.Its dosage and the more difficult assurance of operation.
In addition, the easy particle-bound bacteria of catheter surface, in urethral catheterization, easily infects during leading just.So patient can be resisted for infection
Raw element prevention and treatment, and antibiotic can produce a certain degree of harm to human body.
Therefore, the coefficient of friction on medical catheter surface in use is reduced, it is doctor to improve its hydrophily and anti-infective function
Key issue urgently to be resolved hurrily in being produced and applied with conduit.
The content of the invention
In order to overcome drawbacks described above, the invention provides a kind of micro- profitization processing method of catheter surface.
The technical proposal of the invention is realized in this way：A kind of micro- profitization processing method of catheter surface, its step are as follows：
1）By the strong high polymer material of the hydrophilic of medical grade, water-retaining property, after drying ultra-fine grinding, sieving；
2）Catheter proximal end surface is subjected to melt and dissolvedization processing；Conduit is immersed in the solvent after heating, then carries out gel；
3）By step 1）Pulvis carried out in closed container atomization be suspended into it is density stabilized；
4）By step 2）Conduit after melt and dissolvedization processing is placed in step 3）Closed container in, make its adsorption pulvis and solid
Change.
Further, step 2）Add appropriate antimicrobial agent and/or anaesthetic and step 1）Obtained high polymer material exists
Fully homogenize, then sieve, usually 600-2000 mesh under sterile, dry environment.
Further, step 1）Described high polymer material hydrophilic, that water-retaining property is strong is polyacrylate, acrylates or
Acrylonitrile salt and its polymer of grafting.
Further, step 2）The solvent is cyclohexanone, tetrahydrofuran, dimethylformamide, MEK or first fourth
Ketone, solvent volatility is good, noresidue, it is ensured that conduit is nontoxic.
Further, step 2）Solvent is heated to 10-45 DEG C.
Further, step 4）Conduit vibration after processing, removes unnecessary pulvis and then is vented to nature.
Further, described antimicrobial agent is aminoglycosides or quinolones.
Beneficial effects of the present invention are：1st, the conduit after this micro- profitization, after only 30 seconds need to being contacted with water before use
The lubrication face as " loach " is formed on the surface of its front end, greatly reduces the friction of conduit and bodily tissue.Patient during intubation
Without pain.2nd, micro- profitization surface hydrophilicity is extremely strong, and water-retaining property is good, and lubricating film effect keeps lasting, difficult for drop-off.3rd, well
Biocompatibility, it is not easy to cause cavity to infect.4th, without lubricant especially, the stimulation to cavity is mitigated.5th, convenient operation, can
Pass through that cavity is narrow or scar at, without expanding cavity.6th, handling process is simple, and cost is low.
Embodiment
Explanation is further explained to the present invention with reference to specific embodiment.
Conduit of the embodiment 1 as urethral catheterization, the micro- profitization processing method in its surface, its step are as follows：
By the polyacrylate of medical grade after drying ultra-fine grinding, sieving；Catheter proximal end surface is subjected to melt and dissolvedization processing；Will
Conduit is immersed in 35 DEG C or so of cyclohexanone solvent, then carries out gel；Add appropriate antimicrobial agent aminoglycosides and fiber crops
Medicine and step 1）Obtain polyacrylate fully to homogenize under environment that is sterile, drying, then sieve, usually 600-2000
Mesh；Mixing powder is carried out in closed container atomization be suspended into it is density stabilized；Conduit after melt and dissolvedization processing is placed in
State in closed container, make its adsorption pulvis and solidify；Conduit vibration after processing, removes unnecessary pulvis and then is vented to
Nature.
The conduit that embodiment 2 uses as anal tube, the micro- profitization processing method in its surface, its step are as follows：
By the acrylonitrile salt of medical grade after drying ultra-fine grinding, sieving；Catheter proximal end surface is subjected to melt and dissolvedization processing；It will lead
Pipe is immersed in 40 DEG C or so of dimethylformamide solvent, then carries out gel；Above-mentioned pulvis is subjected to mist in closed container
Change is suspended into density stabilized；Conduit after melt and dissolvedization processing is placed in above-mentioned closed container, makes its adsorption pulvis and consolidates
Change；Conduit vibration after processing, removes unnecessary pulvis and then is vented to nature.
Claims (7)
1. a kind of micro- profitization processing method of catheter surface, it is characterised in that its step is as follows：
1）By the strong high polymer material of the hydrophilic of medical grade, water-retaining property, after drying ultra-fine grinding, sieving；
2）Catheter proximal end surface is subjected to melt and dissolvedization processing；Conduit is immersed in the solvent after heating, then carries out gel；
3）By step 1）Pulvis carried out in closed container atomization be suspended into it is density stabilized；
4）By step 2）Conduit after melt and dissolvedization processing is placed in step 3）Closed container in, make its adsorption pulvis and solid
Change.
2. the micro- profitization processing method of catheter surface according to claim 1, it is characterised in that 2）Add appropriate antimicrobial
Agent and/or anaesthetic and step 1）Obtained high polymer material fully homogenizes under environment that is sterile, drying, then sieves.
3. the micro- profitization processing method of catheter surface according to claim 1, it is characterised in that step 1）It is described it is hydrophilic,
The strong high polymer material of water-retaining property is polyacrylate, acrylates or acrylonitrile salt and its polymer of grafting.
4. the micro- profitization processing method of catheter surface according to claim 1, it is characterised in that step 2）The solvent is ring
Hexanone, tetrahydrofuran, dimethylformamide, MEK or first butanone.
5. the micro- profitization processing method of catheter surface according to claim 1, it is characterised in that step 2）Solvent is heated to
10-45℃。
6. the micro- profitization processing method of catheter surface according to claim 1 or 2, it is characterised in that step 4）After processing
Conduit vibrates, and removes unnecessary pulvis and then is vented to nature.
7. the micro- profitization processing method of catheter surface according to claim 1, it is characterised in that described antimicrobial agent is ammonia
Base glucoside or quinolones.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711047892.0A CN107583111A (en) | 2017-10-31 | 2017-10-31 | A kind of micro- profitization processing method of catheter surface |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711047892.0A CN107583111A (en) | 2017-10-31 | 2017-10-31 | A kind of micro- profitization processing method of catheter surface |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107583111A true CN107583111A (en) | 2018-01-16 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711047892.0A Pending CN107583111A (en) | 2017-10-31 | 2017-10-31 | A kind of micro- profitization processing method of catheter surface |
Country Status (1)
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Citations (8)
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|---|---|---|---|---|
| EP0480809A2 (en) * | 1990-10-04 | 1992-04-15 | Terumo Kabushiki Kaisha | Medical device |
| CN1340392A (en) * | 2000-08-25 | 2002-03-20 | 清水食品株式会社 | Prilling of metal powder or ceramic powder and its making method and manufacture method of sintered material with prilling powder as raw material |
| CN1422308A (en) * | 2000-02-08 | 2003-06-04 | 国际涂料有限公司 | Powder coating compositions |
| CN101455861A (en) * | 2008-12-17 | 2009-06-17 | 东南大学 | Lubricity coatings preparation method on the medical catheter polymers surface |
| CN202342238U (en) * | 2011-08-05 | 2012-07-25 | 上海圣博艾医疗科技有限公司 | Ureteral stent |
| CN102973986A (en) * | 2012-07-19 | 2013-03-20 | 黄斌 | Medical super-lubricity antibacterial catheter coating liquid |
| CN202909253U (en) * | 2012-11-09 | 2013-05-01 | 上海圣博艾医疗科技有限公司 | Self-lubricating type antibacterial medical catheter |
| CN105412995A (en) * | 2015-12-04 | 2016-03-23 | 江苏道森新材料有限公司 | Medical catheter and method for forming antibacterial hydrophilic coating on surface of medical catheter |
-
2017
- 2017-10-31 CN CN201711047892.0A patent/CN107583111A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0480809A2 (en) * | 1990-10-04 | 1992-04-15 | Terumo Kabushiki Kaisha | Medical device |
| CN1422308A (en) * | 2000-02-08 | 2003-06-04 | 国际涂料有限公司 | Powder coating compositions |
| CN1340392A (en) * | 2000-08-25 | 2002-03-20 | 清水食品株式会社 | Prilling of metal powder or ceramic powder and its making method and manufacture method of sintered material with prilling powder as raw material |
| CN101455861A (en) * | 2008-12-17 | 2009-06-17 | 东南大学 | Lubricity coatings preparation method on the medical catheter polymers surface |
| CN202342238U (en) * | 2011-08-05 | 2012-07-25 | 上海圣博艾医疗科技有限公司 | Ureteral stent |
| CN102973986A (en) * | 2012-07-19 | 2013-03-20 | 黄斌 | Medical super-lubricity antibacterial catheter coating liquid |
| CN202909253U (en) * | 2012-11-09 | 2013-05-01 | 上海圣博艾医疗科技有限公司 | Self-lubricating type antibacterial medical catheter |
| CN105412995A (en) * | 2015-12-04 | 2016-03-23 | 江苏道森新材料有限公司 | Medical catheter and method for forming antibacterial hydrophilic coating on surface of medical catheter |
Non-Patent Citations (2)
| Title |
|---|
| 李干佐等编著: "《微乳液理论及其应用》", 31 October 1995, 石油工业出版社 * |
| 王聘: "医用导管表面亲水润滑改性", 《中国优秀硕士学位论文全文数据库 医药卫生科技辑》 * |
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Application publication date: 20180116 |