The content of the invention
It is an object of the invention to provide a kind of compound moxa stick for being used to treat obesity, for treating spleen kidney in youth group
Deficiency of yang type obeisity.
It is a further object of the present invention to provide the preparation method of above-mentioned compound moxa stick.
The technical solution adopted in the present invention is a kind of compound moxa stick for being used to treat obesity, according to mass percent
Including following raw material:Monkshood 7.124%~10.00%, Chinese cassia tree 7.124%~10.00%, rhizoma zingiberis 7.124%~10.00%,
Cloves 7.124%~10.00%, rhizoma atractylodis 7.124%~10.00%, asarum 7.124%~10.00%, the root of Dahurain angelica 7.124%~
10.00%th, rhizome of chuanxiong 7.124%~10.00%, semen brassicae 7.124%~10.00%, realgar 7.124%~10.00%, safflower
7.124%~10.00%, fennel seeds 7.124%~10.00%, above material quality percentage sum are 100%, will be above-mentioned
Raw material mixes with moxa, produces.
The features of the present invention also resides in,
The mass ratio of raw material and moxa is 1:4.
Another technical scheme of the present invention is a kind of preparation method for being used to treat the compound moxa stick of obesity,
Implement according to following steps:
Step 1, raw material is weighed:
Proportionally weigh monkshood, Chinese cassia tree, rhizoma zingiberis, cloves, rhizoma atractylodis, asarum, the root of Dahurain angelica, rhizome of chuanxiong, semen brassicae, realgar, safflower,
Fennel seeds;
Step 2, powder processed:
Impalpable powder is ground into after the raw material that step 1 weighs is ultrasonically treated;
Step 3, moxa stick processed:
Mixed powder made from step 2 is mixed with moxa, twists as moxa stick, produces.
The features of the present invention also resides in,
The dosage of each raw material is monkshood 7.124%~10.00%, Chinese cassia tree 7.124%~10.00%, rhizoma zingiberis in step 1
7.124%~10.00%, cloves 7.124%~10.00%, rhizoma atractylodis 7.124%~10.00%, asarum 7.124%~
10.00%th, the root of Dahurain angelica 7.124%~10.00%, rhizome of chuanxiong 7.124%~10.00%, semen brassicae 7.124%~10.00%, realgar
7.124%~10.00%, safflower 7.124%~10.00%, fennel seeds 7.124%~10.00%, above material quality percentage
It is 100% than sum.
Step 2 is specially:It is coarse powder that all raw materials, which are crushed, adds in distilled water, obtains mixing suspension;Then to mixed
Close suspension and carry out sonic oscillation processing, obtain dispersion soln;Finally dispersion soln is centrifuged, respectively to sediment and upper
Clear liquid is dried, is ground into impalpable powder, mixes and produces.
Sonic oscillation processing time is 2.5~3.5h.
The drying of sediment is:Sediment is dried in vacuo at 50~60 DEG C, requires that moisture is less than after drying
0.1%.
Supernatant is dried using freeze-drying, and drying pressure is 10~40Pa, and drying temperature is -50~-10 DEG C, is dried
Time is 17~19h.
The mass ratio of mixed powder and moxa is 1 in step 3:4.
The invention has the advantages that a kind of compound moxa stick for being used to treat obesity of the present invention, used folium artemisiae argyi tool
Play the role of warmly nourishing Yangqi, more assistant helped monkshood, Chinese cassia tree, rhizoma zingiberis, cloves, rhizoma atractylodis, asarum, the root of Dahurain angelica, rhizome of chuanxiong, semen brassicae, realgar,
Safflower, fennel seeds etc. enter the Chinese medicine of the yang-tonifying QI invigorating of the warp of spleen kidney, are capable of the sun of temperature fortune spleen kidney and accelerate loss of weight, while choose conjunction
Suitable acupuncture point carries out moxa-moxibustion, can play function of spleen and stomach regulating, change the turbid effect of fat drop and reach the purpose of fat-reducing, in youth group
Yang deficiency of spleen and stomache obeisity patient has the effect of notable.
Embodiment
With reference to embodiment, the present invention is described in detail.
A kind of compound moxa stick for being used to treat obesity of the present invention, including following raw material:Monkshood 7.124%~10.00%,
Chinese cassia tree 7.124%~10.00%, rhizoma zingiberis 7.124%~10.00%, cloves 7.124%~10.00%, rhizoma atractylodis 7.124%~
10.00%th, asarum 7.124%~10.00%, the root of Dahurain angelica 7.124%~10.00%, rhizome of chuanxiong 7.124%~10.00%, semen brassicae
7.124%~10.00%, realgar 7.124%~10.00%, safflower 7.124%~10.00%, fennel seeds 7.124%~
10.00%, above material quality percentage sum is 100%, by above-mentioned raw materials according to mass ratio 1:4 mix with moxa, produce.
The above-mentioned preparation method for being used to treat the compound moxa stick of obesity, implements according to following steps:
Step 1, raw material is weighed:
Proportionally weigh monkshood, Chinese cassia tree, rhizoma zingiberis, cloves, rhizoma atractylodis, asarum, the root of Dahurain angelica, rhizome of chuanxiong, semen brassicae, realgar, safflower,
Fennel seeds;
Step 2, powder processed:
It is coarse powder that the raw material that step 1 weighs, which is crushed, adds in distilled water, obtains mixing suspension;Then it is outstanding to mixing
Supernatant liquid carries out sonic oscillation and handles 2.5~3.5h, obtains dispersion soln;Finally dispersion soln is centrifuged, respectively to precipitation
Thing and supernatant are dried, are ground into impalpable powder, mix and produce;
The drying of sediment is:Sediment is dried in vacuo at 50~60 DEG C, requires that moisture is less than after drying
0.1%.
Supernatant is dried using freeze-drying, and drying pressure is 10~40Pa, and drying temperature is -50~-10 DEG C, is dried
Time is 17~19h.
The present invention carries out sonic oscillation processing to stock suspension, and ultrasonic wave transmittance process is also the process of energy transmission,
Calorifics effect can be caused in the process.Fuel factor can cause the change of human vas function and metabolic process, and occur one
The complicated neural reflex of series, various effects are produced in tissue, at the same there are some researches show ultrasonic wave can promote circulation,
Accelerate the effects such as the softening of tissue, the metabolism for increasing cell.
Step 3, moxa stick processed:
By mixed powder made from step 2, according to mass ratio 1:4 mix with moxa, twist as moxa stick, produce.
In compound moxa stick of the present invention, the Chinese herbal medicine such as monkshood, Chinese cassia tree, rhizoma zingiberis, realgar, cloves, fennel seeds is yang-tonifying cold dispelling
Medicine, there is the effect of warming middle-JIAO and strengthening the spleen, mends fire supporing yang;The root of Dahurain angelica, Ligusticum wallichii, safflower are promoting blood circulation and removing blood stasis, clearing and activating the channels and collaterals effect, tool
Having improves the sanguimotor effect of surrounding tissue;The eliminating dampness and eliminating phlegm effect of rhizoma atractylodis, semen brassicae can remove the outer phlegm of flesh side film.It is all
Medicine is by the warming and activating meridian and the property dredging the channel of its pure sun of folium artemisiae argyi, the purpose of tonifying spleen and kidney yang-energy and then fat-eliminating slimming.
During treatment, heat when being burnt using medicine, related acupuncture point is stimulated by the method for hanging moxibustion, its fuel factor excites people
Body opens the local skin flesh natural fibre line of meat, medicine is reached in corresponding acupuncture point thoroughly, plays thin channels and activating collaterals, tonifying spleen and kidney yang-energy, Jin Erwen through gas
Resolving sputum is drunk, and dispels the purpose that the turbid fat of phlegm wet reaches fat-reducing.
1 data and method
1.1 general information
Xi'an Malus spectabilis Professional School obesity patient in December, -2016 in December, 2,015 100 is selected, wherein man 24,
Female 76.Clear Chinese mugwort group and medicine Chinese mugwort group are divided into using random digits table, each 50.Wherein clear Chinese mugwort group man 13, female 37, height
156~178cm;Man 11 in control group, female 39,157~178cm of height, two groups of ages at 17~21 years old, average age
18.8 years old.Two groups of Genders, age and height comparing difference are not statistically significant (P > 0.05), have comparativity.It is shown in Table 1.
1 two groups of general information of table compare
Note:Compared with clear Chinese mugwort group, * P < 0.05
1.2 diagnostic criteria
1.2.1 Western medicine diagnostic criteria
According to formal proposition " suggestion that Chinese Adult constitutional index is classified " in 2001, it thought that the BMI of Chinese judges
Standard is:Normally:18.5 < BMI < 23.9 are overweight:24 < BMI < 27.9 are fat:BMI≥28;Normal waist size man < 85 is public
Divide, 80 centimeters of female <, fat waistline man >=85 centimeters, female >=80 centimeter.
1.2.2 tcm diagnosis standard
Promulgated with reference to State Administration of Traditional Chinese Medicine in 1994《Chinese medical disease diagnoses and criterion of therapeutical effect》, obesity is divided into stomach
Four kinds of heat stagnation spleen, stagnation of the circulation of vital energy blood addiction, insufficiency of the spleen phlegm pond and the insufficiency of both the spleen and the kindey tcm clinical practice partings.Wherein yang deficiency of spleen and stomache:Body is fat, face
Face is impractical, and god is tired thermophilic sleeping, shortness of breath and fatigue, abdominal distension loose stool, spontaneous perspiration asthma, it is dynamic then more very, aversion to cold and cold limbs, edema of lower extremity, it is few to urinate daytime
Night frequency, the fat tongue of pale tongue is thin white, deep thready pulse.
1.3 inclusive criteria
(1) simple obesity patient, and body mass index BMI > 24.0 are clinically diagnosed as;
(2) Chinese medical discrimination is the patient of yang deficiency of spleen and stomache obesity;
(3) age of research object is 17-25 year;
(4) any method slimmer was not received in nearly three months;
(5) researcher can be coordinated to complete subject study.
1.4 exclusion standard
(1) simple obesity diagnostic criteria person is not met, Secondary Obesity is excluded, such as hypophysis disease, hypothalamic disorder, first
Shape adenasthenia disease, pancreas islet disease, gonad function weakens disease, adrenal cortex function enters disease, post menopausal obesity etc. especially;
(2) yang deficiency of spleen and stomache obesity patient is removed in Chinese medical discrimination;
(3) primary disease and the cyclothymics such as the serious cardiovascular and cerebrovascular of other classes, liver kidney and hemopoietic system are associated with
Person;
(4) other any treatment method slimmers were once received in nearest 3 months;
(5) this treatment or voluntarily plus with other treatment methods can not be adhered to, so as to have influence on the collection of this research data
And the evaluation person of curative effect;
(6) other cases of inclusive criteria requirement are not met.
The processing of 1.5 fortuitous events
Dizzy moxibustion patient may occur in which ice-cold unexpected dizzy, nausea and vomiting, pale complexion, trick, drop in blood pressure, having palpitation
Sweat, even fall in a swoon, the symptom such as arteries and veins is thin.Occur that the reason for this symptom is mostly first moxibustion, tired, frightened, weak, posture is not on an empty stomach
When, moxibustion wick is excessive, it is overweight etc. to stimulate, one it has been observed that stop moxibustion immediately, advises patient to lie down, anxious moxibustion Zusanli, in acupuncture people, typically
Without very dangerous.Dizzy moxibustion is although rare, but should be noted that the taboo of moxibustion, carries out prevention work, constantly to pay attention in moxibustion and observe,
Strive for the early processing of early discovery, anti-relieving fainting moxibustion is preferably.
2 treatments and observation
2.1 treatment method
2.1.2 acupuncture point and foundation are chosen
Master point:Guanyuan point, TIANSHU acupoint, MINGMEN acupoint, Shen Shu point, Pishu Points, point st 36.
Select cave foundation:The heresy of phlegm wet is born in spleen and formed in kidney, and the yang-energy of spleen kidney is only transported by temperature can just reach eliminating the phlegm
The purpose of wet fat-reducing, close in formula the caves such as member, the gate of vitality play the role of it is tonifying spleen and kidney.
Clear Chinese mugwort group:Away from applying outstanding pin, each 15min, day 1 time, continuous moxibustion 20d at the 1-2cm of acupuncture point.Period normal diet.
Medicine Chinese mugwort group:Moxibustion is done with clear Chinese mugwort group.
2.2 observation index and measuring method
Two groups of parameters for observation on effect:Body weight (kg), waistline (WC) and body mass index (BMI)
(1) body weight measurement:Weigh in and loosened with corrected level type body weight kind, subject's whole body, uprightly
The middle part on chassis under detention;Survey crew reads the slider position in lever kind, accuracy of reading to lOg.
(2) height measurement method subject should on an empty stomach, take off one's shoes, only wear frivolous clothes;The gage for measuring height should be with
Ground is vertically fixed or pastes on the wall;Subject is upright, two heels close up close to gage, and two shoulders and buttocks are also pressed close into amount
Chi;Survey crew is placed on the crown of subject with a square, two sides at right angle is approached while being close to gage another side
The scalp of subject, read the reading on gage.
(3) calculation formula of body mass index:
Body mass index (BMI) (kg/m2)=body weight (kg)/height2(m2)
(4) waistline (WC) measuring method:Naturally stand, bipod separate 30-40cm in the case of, with one without elasticity,
Minimum scale is 1mm tape measure, is placed on the midpoint of the measured hipbone upper limb and twelfth rib bone lower edge line, in the horizontal direction
Around belly one week.During measurement, tape measure is close to skin surface, but can not strangle skin, and waistline is measured at normal exhalation end
Length.Pay attention to while measurement, around there are an at least personnel, in order to avoid cause the collimation error.
2.3 criterion of therapeutical effect
Due to there is no unified criterion both at home and abroad, therefore revised with reference to the obesity academic conference of the 5th, the whole nation《It is single
The diagnosis of pure property obesity and efficacy assessment standard》And formulate.It is effective:Body weight loss >=5kg, WC declines >=8cm, BMI decline
≥3;Effectively:Clinical symptoms substantially mitigate, Body weight loss >=3kg, and WC declines >=4cm, BMI declines >=1.5 but≤3;It is invalid:Body
Decline < 3kg again, WC declines < 4cm, and BMI declines < 1.5.
Total effective rate (%)=obvious effective rate+effective percentage.
2.4 statistical method
As a result analyzed using SPSS13.0 softwares, measurement data Normal Distribution is with means standard deviation (χ scholar s)
Represent, it is neat to compare variance between group, using independent samples t-test;Heterogeneity of variance, examined using t '.Disobey normal distribution and use middle position
Number and quartile spacing are expressed, and are compared between group using rank test.Enumeration data is expressed with rate, is compared between group and is examined using card side
Test, level of significance α=0.05.
3 curative effects
The comparison of two groups of body weight, waistline and BMI indexes before 3.1 experiments
As shown in Table 2, clear Chinese mugwort group and medicine Chinese mugwort group body weight, waistline and the equal indifference of BMI indexes (equal P > 0.05).
Table 2 tests the comparison of basic numerical value between first two groups
Note:Compared with clear Chinese mugwort group, * P < 0.05
The change of two groups of body weight, waistline and BMI indexes after 3.2 experiments
As shown in Table 3, with clear Chinese mugwort group it was found that, medicine Chinese mugwort group body weight and waistline are decreased obviously, and difference is respectively provided with statistics
Learn meaning (equal P < 0.05);Medicine Chinese mugwort group BMI is decreased obviously compared to clear Chinese mugwort group, has significant difference (P < 0.01).
Substantially the comparison of numerical value between two groups after the experiment of table 3
Note:Compared with clear Chinese mugwort group, * P < 0.05
The change of the pretherapy and post-treatment body weight of 3.3 two groups of patients, waistline and BMI
From table 4, found using paired-sample t test in group, compared with pre-treatment compared with, two groups of patients after the treatment
Different degrees of decline is presented in body weight, waistline and BMI, and difference has statistical significance (equal P < 0.05).
The change of 4 two groups of pretherapy and post-treatment correlation values of patient of table
Note:Compared with pre-treatment compared with * P < 0.05
3.4 curative effects compare
From table 5, two groups of patient's curative effects compare, and clear Chinese mugwort group total effective rate is 34%, and medicine Chinese mugwort group total effective rate is 88%,
With significant difference (χ2=37.965, P < 0.01).
The comparison of 5 two groups of curative effects of table
3.5 safety evaluatio
During treatment, two groups of patients do not have found that moxa-moxibustion has harmful effect to the normal physiological status index of patient, and
Do not occur the generation of the adverse reactions such as dizzy moxibustion.
4 conclusions
The fertile more abundant expectorations of people are wet, and phlegm wet category is cloudy evil, and the heresy of phlegm wet is born in spleen and formed in kidney, former according to the normal treatment of theory of traditional Chinese medical science
Reason, the ruling by law of the warm sun of heresy application of cold sensation of the genitalia.The present invention has the function that warmly nourishing Yangqi from the product folium artemisiae argyi of pure sun, and more assistant helps
Monkshood, Chinese cassia tree, rhizoma zingiberis, cloves, rhizoma atractylodis, asarum, the root of Dahurain angelica, rhizome of chuanxiong, semen brassicae, realgar, safflower, fennel seeds etc. enter the warp of spleen kidney
The Chinese medicine of yang-tonifying QI invigorating, so as to the purpose for reaching the sun of temperature fortune spleen kidney and accelerating loss of weight;In point selection formula close member, the gate of vitality, shen shu,
Pishu, Zusanli etc. are the acupuncture point of tonifying spleen and kidney yang-energy.The other middle part of gastric cavity, Zusanli have appetite-suppressing to weaken gastrointestinal peristalsis
Effect, Tianshu, big horizontal, Guan Yuan conditionings internal organs, qi-regulating defaecation, disperse accumulations lipid-loweringing;Sanyinjiao invigorating spleen to remove dampness fat drop is turbid.Pass through moxa-moxibustion
Function of spleen and stomach regulating can be played, changes the turbid effect of fat drop and reaches the purpose of fat-reducing.
Whether this experiment simultaneously loses weight successful leading indicator using body weight and waistline as patient.The change of body weight can be straight
The reversed degree that should lose weight.WC is the overall target for reflecting amount of total fat and Fat Distribution, is as the survey for judging Central obesity
Figureofmerit, and the hazards of angiocardiopathy are predicted well.There is research to claim WC and High blood pressure levels and the relation of layering
It is proportionate.
LEIHUO moxibustion method in this experiment caused physical agent and the medicine factor, the special work with acupuncture points on the human body in burning
It is combined with the special pathway of, channels and collaterals, caused one kind " comprehensive effect ".Its caused emittance is infrared ray and near-infrared
Line, by forming highly concentrated medicine area to people's honorable (perilesional), position (focus position), cave, in the presence of heating power, penetrate into tissue
Deep adjusts human body items function.It can encourage the hydrogen bond of biomolecule in human acupoint, and pertinent resonance absorption is excited in generation
Effect, the energy needed for human body cell is adjusted by neurohumoral systems, reaches temperature three-way meridian, expelling wind and clearing away cold, activates blood circulation and disperses blood clots, dissipates
Goitre dissipates knurl, strengthening vital QI to eliminate pathogenic factors and other effects treatment human body diseases.The regulation of channels and collaterals, acupuncture points on the human body to body is internal cause, and the burning of medicine is outer
Cause, both are indispensable.
In summary, Chinese mugwort is passed through to yang deficiency of spleen and stomache obeisity patient in youth group using compound moxa stick of the present invention
Moxibustion treatment treats obesity, has the effect of notable.