CN107582221B - For treating the device of nasosinusitis and expansion nasal sinus opening - Google Patents
For treating the device of nasosinusitis and expansion nasal sinus opening Download PDFInfo
- Publication number
- CN107582221B CN107582221B CN201710545351.4A CN201710545351A CN107582221B CN 107582221 B CN107582221 B CN 107582221B CN 201710545351 A CN201710545351 A CN 201710545351A CN 107582221 B CN107582221 B CN 107582221B
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- main body
- sinus
- nasal sinus
- opening
- nasosinusitis
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M29/00—Dilators with or without means for introducing media, e.g. remedies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
- A61L2300/604—Biodegradation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/105—Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M29/00—Dilators with or without means for introducing media, e.g. remedies
- A61M29/02—Dilators made of swellable material
- A61M2029/025—Dilators made of swellable material characterised by the guiding element
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0681—Sinus (maxillaris)
Abstract
The present invention is provided to treat the device of nasosinusitis and expansion nasal sinus opening, it is free from side effects and is open in nasal sinus biodegradable to human body.In addition, the present invention provides economic and safety the device for treating nasosinusitis and expanding nasal sinus opening.For this purpose, one embodiment of the invention discloses a kind of device for treating nasosinusitis and expanding nasal sinus opening, which includes: main body, is made of the Biodegradable material being decomposed after the 1st set time in human body;And the therapeutic agent of paranasal sinusitis, it is coated on at least one side of the main body, the main body coated with the therapeutic agent is inflated after being inserted into reduced nasal sinus opening.
Description
Technical field
The present invention relates to the devices for treating nasosinusitis and expansion nasal sinus opening.More particularly, to nasal sinus can be opened
Mouth expansion, and the biodegradable device for treating nasosinusitis and expanding nasal sinus opening that is open in nasal sinus.
Background technique
Nasal sinus is in the skull being connect and being called the small opening portion of aperture with nasal cavity (nasal canal: nasal tube)
Cavity.Each aperture between nasal sinus and nasal cavity is formed and being the bone by being covered by mucous membrane tissue layer.In general, empty
Gas by aperture enter nasal sinus in and out of nasal sinus it is externally discharged.In addition, mucus is continued by the mucous membrane internal layer of nasal sinus
It is formed, is discharged in nasal cavity by aperture.
Nasosinusitis refers to the general term of the inflammation in more than one nasal sinus.Acute sinusitis may cause tissue
Edema can also interfere the normally ventilation via the discharge of aperture and nasal sinus for the moment, is possible to according to the collection degree of mucus
Cause the infection in paranasal sinus, is related to the infection of the upper respiratory tract or anaphylactic disease.Chronic nasosinusitis is to cause the chronic sense of nasal sinus
Dye and inflammation, the chronicity disease characterized by the reduced or blocking of the duration of more than one nasal sinus aperture.It is chronic
Nasosinusitis is usually related with allergic airway disease lasting for a long time, nasal polyp, hypertrophy concha and/or deviation of nasal septum.It is acute
Nasosinusitis is by typical single pathogen (for example, the mushroom of the bacterium of a type, the virus of type, type
Deng) caused by infection and cause, and chronic nasosinusitis is usually with multiple pathogenic bacterial infections (for example, type more than one is thin
Bacterium or the microorganism of the type more than one) it is related.
It, can tissue and/or bone knot to secondary nose anatomical structure in the case where not treating chronic nasosinusitis and shelve
Structure brings the damage of unrepairable.Usually using decongestant, steroids nasal mist in the initial therapy of chronic nasosinusitis
And drug as antibiotic (in the case where being infected as caused by bacterium).The case where only being can not be restored by drug therapy
Under, it will usually it is recommended that surgical intervention.
Acclarent company (Acclarent Inc) where California, USA door Lip river Parker is in order to treat nose
Sinusitis and have developed the technology for being called nasal sinus balloon dilatation (Balloon Sinuplasty) TM and for executing the operation
System.In the multiple United States Patent (USP)s and patent that U.S. Patent No. No. 7645272, No. 7654997 and No. 7803150 are representative
Described in application the various embodiments of nasal sinus balloon dilatation TM operation and used in the execution of such operation it is various
Device.In nasal sinus balloon dilatation TM operation, conduit (guide catheter) is inserted into nose, the nasal sinus of morbidity is placed in
Aperture in or position adjacent thereto.Then, conducting wire (guidewire) is proceeded in the nasal sinus of morbidity by conduit.It
Afterwards, the dilating catheter for having distensible expander (for example, expandable sacculus) is located at morbidity to expander on conducting wire
Advance position in the aperture of nasal sinus.Then, expander is extended, without cutting mucous membrane or without removing any bone
In the case of, realize the expansion of aperture and the regeneration of the bone adjacent with aperture.Then, conduit and conducting wire are removed, and passes through expansion
Aperture and improve the exhaust of the nasal sinus of idiopathy and make its ventilation.
But in such previous method and device, it is difficult to constantly inject drug to the nasal sinus of patient opening, be
Injection drug and the conduit used be it is disposable, to be discarded after once perform the operation, although sometimes can be by killing
Bacterium reuses identical patient, but most conduit needs discarded, therefore results in waste of resources.
Summary of the invention
The project to be solved
The present invention provides a kind of pair of human body and is free from side effects and is open in nasal sinus biodegradable for treating nasosinusitis
And expand the device of nasal sinus opening.
In addition, the present invention provides a kind of economic and safety the device for treating nasosinusitis and expanding nasal sinus opening.
In addition, the invention solves technical task be not limited to technical task mentioned above, those skilled in the art are logical
Record below crossing should be clearly understood that in this others not mentioned technical task.
The means to solve the problem
One embodiment of the invention for treat nasosinusitis and expand nasal sinus opening device include: main body, by
The Biodegradable material being decomposed after the 1st set time in human body is constituted;And the therapeutic agent of paranasal sinusitis,
At least one side coated on the main body, the main body coated with the therapeutic agent are inserted into reduced nasal sinus and are open it
After be inflated.
In addition, the main body has columnar eyed structure.
In addition, the main body is made of the suture of elasticity.
In addition, further include film, which surrounds the main body of contraction state, by human body the set the 2nd
The Biodegradable material being decomposed after time is constituted, and the 2nd time is shorter than the 1st time.
In addition, further including insertion tube, the main body which is coated with the therapeutic agent is inserted into the quilt
The nasal sinus of diminution is open, and the main body is inflated when being discharged from the insertion tube.
In addition, further including foley's tube, the main body which is coated with the therapeutic agent is inserted into institute
Reduced nasal sinus opening is stated, the main body is configured to surround the sacculus of the foley's tube, and the main body passes through the ball
The expansion of capsule and be inflated.
Invention effect
Of the invention is free from side effects to human body and opens in nasal sinus for treating nasosinusitis and expanding the device that nasal sinus is open
Mouth is biodegradable.
In addition, the device economy and safety for treating nasosinusitis and expanding nasal sinus opening of the invention.
In addition, effect of the invention is not limited to effect mentioned above, those skilled in the art can by following record
It is expressly understood in this others not mentioned effect.
Detailed description of the invention
Attached drawing below appended by this specification instantiates the preferred embodiment of the present invention, is conducive to and reality of the invention
It applies mode to help to understand technical idea of the invention together, but the present invention should not be limited only to item documented by such attached drawing
It explains.
Fig. 1 and Fig. 2 shows one embodiment of the invention for treat nasosinusitis and expand nasal sinus opening device it is swollen
Swollen front and back.
Fig. 3 and Fig. 4 shows the device for treating nasosinusitis and expansion nasal sinus is open of another embodiment of the present invention.
Fig. 5 is the sectional view for showing nasal sinus opening and being reduced and occur nasosinusitis.
Fig. 6 is to show for the device for being used to treat nasosinusitis and expanding nasal sinus opening of one embodiment of the invention to be applied to
The sectional view of nasal sinus opening.
Fig. 7 shows the device for treating nasosinusitis and expansion nasal sinus is open of still another embodiment of the invention.
Fig. 8 is to show the device for being used to treat nasosinusitis and expanding nasal sinus opening of Fig. 7 being applied to cutting for nasal sinus opening
Face figure.
Fig. 9 shows the device for treating nasosinusitis and expansion nasal sinus is open of still another embodiment of the invention.
Figure 10 and 11 is to show for the device for being used to treat nasosinusitis and expanding nasal sinus opening of Fig. 9 to be open applied to nasal sinus
Sectional view.
The explanation of appended drawing reference
100: main body 200: film
300: insertion tube 400: foley's tube
Specific embodiment
In the following, referring to attached drawing, to a preferred embodiment of the present invention will be described in detail.
The embodiment of the present invention is provided to more completely illustrate the present invention to those skilled in the art, below
Embodiment can be deformed into various other forms, and the scope of the present invention is not limited to the following examples.Instead, these embodiments be for
The disclosure is provided more and complete and completely transmit thought of the invention to those skilled in the art and provide.
In addition, each structure in attached drawing below for the convenience of explanation property and definition and be greatly exaggerated to show,
Identical appended drawing reference refers to identical element in attached drawing.As used in this specification, term " and/or " be included in this and list
Project in one and more than one all combinations.
Term used in this specification is to illustrate specific embodiment and use, and does not have to the present invention and limits
Effect.
As used in this specification, when singular form not yet explicitly points out other situations in the text, it may include plural
Form.In addition, in the present specification, " including (comprise) " and/or " including (comprising) " are to related shape
Shape, number, step, movement, the presence of component, element and/or their combination are determined, rather than to exclude more than one
Other shapes, number, movement, component, element and/or their combination there is a situation where or it is additional.
Fig. 1 and Fig. 2 shows one embodiment of the invention for treat nasosinusitis and expand nasal sinus opening device it is swollen
Swollen front and back.
Referring to FIG. 1 and FIG. 2, one embodiment of the invention includes for treating nasosinusitis and expanding the device that nasal sinus is open
Main body 100.
Main body 100 is made of substance biodegradable after the 1st time in human body, although it is not shown, but in table
Face is coated with paranasal sinusitis therapeutic agent.
In addition, main body 100 can be open as the substance for having elasticity in nasal sinus expands (expansion), propped up by a kind of elasticity
Frame constitutes and nasal sinus can be open and expand.
That is, main body 100 is inserted into nasal sinus opening and is inflated, expanded so that reduced nasal sinus is open, and in institute
1st time of setting is biodegradable later and from human body natural is discharged.
Here, being approximately set to about the 1st time in order to treat nasosinusitis 30 days or so, dropped in main body 100 by biology
Paranasal sinusitis therapeutic agent is sustainably put into during solution.Certainly, it can set for the 1st time according to the weight of patient.
Preferably, such main body 100 is constituted by having biodegradable and having elastic suture, is formed as compiling
Columnar mesh (mesh) structure knitting suture and being formed.
Here, about the material for forming main body 100 and coated on the paranasal sinusitis therapeutic agent of main body 100, it can be according to trouble
The weight of person and be formed as different thickness by a variety of materials, therefore this is omitted and is described in detail.
Fig. 3 and Fig. 4 shows the device for treating nasosinusitis and expansion nasal sinus is open of the other embodiment of the present invention.
Referring to Fig. 3 and Fig. 4, the device packet for treating nasosinusitis and expansion nasal sinus is open of the other embodiment of the present invention
Include the film 200 for surrounding main body 100.
Film 200 pressurizes to main body 100 and surrounds, so that main body 100 keeps the shape before expansion.Here, such as Fig. 3 institute
Show, film 200 can accordingly be formed with the entire length of main body 100, as shown in figure 4, film (210,220) can also be formed as
Only partially surround the both side ends of main body 100.
Such film 200 is made of substance biodegradable after the 2nd time in human body.Here, the 2nd time
It is set as the time shorter than the 1st above-mentioned time, preferably, is approximately set within 24 hours.
As film 200 is decomposed, the main body 100 inside film 200 expands as illustrated in fig. 2, so as to be contracted
Small nasal sinus, which is open, to be expanded.
Fig. 5 is the sectional view for showing nasal sinus opening and being reduced and occur nasosinusitis, and Fig. 6 is shown an implementation of the invention
The device for treating nasosinusitis and expansion nasal sinus opening of example is applied to the sectional view of nasal sinus opening.
Referring to Fig. 5 and Fig. 6, above-mentioned nasal sinus is as the empty sky in the skull for connect with nasal cavity and being covered by mucous membrane
Between, it is made of maxillary sinus (MS, jawbone sinus), sinus frontalis (FS, preceding sinus frontalis), sieve sinus (honeycomb), sphenoid sinus (butterfly nest) etc..Such nasal sinus
It is arranged in a column (lined with) with the epithelial tissue for generating mucus, forms the state with nasal cavity dredging.Generally, pass through epithelium
Tissue and the mucus formed are slowly discharged and being called the opening of paranasal sinus mouth from each paranasal sinus.In these channels,
If an epithelial tissue generates inflammation for some reason, intercepted by the cavity that its channel is discharged.It is blocked in this way
The state cut can be periodically (constantly generating pain as a result) or chronic.Cause is relevant to the discharge of mucus in this way
Obstacle (for example, paranasal sinus mouth is intercepted), can produce mucous membrane in nasal sinus and intercepted showing for (mucosal congestion)
As.The chronic mucous membrane of paranasal sinus intercepts the upper belt of phenomenon pair and paranasal sinus side by side to damage, in the future because of partial pressure of oxygen
(oxygentension) inflammatory reaction as reduction, microbial reproduction (for example, nasosinusitis, sinusitis) and cause inflammation
Disease.
Here, in the present invention, with each opening (1,2) of maxillary sinus MS and sinus frontalis FS is reduced (intercepting) and generates scorching
It is illustrated in case where disease 10.
As described above, the flowing of mucus is intercepted, upper when the opening (1,2) of maxillary sinus MS or sinus frontalis FS is reduced
Jaw sinus MS or sinus frontalis FS generates inflammation 10.
It is of the invention for treating nasosinusitis and expansion when being inserted into the opening (1,2) of maxillary sinus MS or sinus frontalis FS referring to Fig. 6
When opening the device of nasal sinus opening, in the case where being free from side effects to human body, in 100 quilt of main body that nasal sinus is open biodegradable
It expands and expands opening (1,2), so as to put into paranasal sinusitis therapeutic agent into maxillary sinus MS or sinus frontalis FS.
Fig. 7 shows the device for treating nasosinusitis and expansion nasal sinus is open of still another embodiment of the invention, and Fig. 8 is
The device for being used to treat nasosinusitis and expanding nasal sinus opening of Fig. 7 is applied to the sectional view of nasal sinus opening, Fig. 9 shows the present invention
Still another embodiment for treat nasosinusitis and expand nasal sinus opening device, Figure 10 and 11 is to show for Fig. 9 to be used for
It treats nasosinusitis and the device for expanding nasal sinus opening is applied to the sectional view of nasal sinus opening.
Firstly, the device for treating nasosinusitis and expansion nasal sinus opening of the invention is in insertion tube referring to Fig. 7 and Fig. 8
300 inside includes main body 100, and main body is discharged from the insertion tube 300 for the opening (1,2) for being inserted into maxillary sinus MS or sinus frontalis FS
100, so that main body 100 is positioned at the opening (1,2) of maxillary sinus MS or sinus frontalis FS.Certainly, as above-mentioned, although it is not shown, in main body
100 outer peripheral surface can be formed with the film for inhibiting the expansion of main body 100.
In addition, referring to Fig. 9 to Figure 11, it is of the invention for treat nasosinusitis and expand nasal sinus opening device further include by
Distal portions (distal portion) 410, proximal part (proximal portion) 430 and 420 structure of distensible sacculus
At foley's tube 400, main body 100 be formed as surround sacculus 420 outer peripheral surface.
Here, the expansion method of sacculus 420 is well known technology, therefore omit detailed description.
In addition, as the sacculus 420 for the opening (1,2) for being configured at maxillary sinus MS or sinus frontalis FS is inserted by lead W
It is expanded into the foley's tube 400 of maxillary sinus MS or sinus frontalis FS, so that main body 100 is inflated, thus main body 100 is positioned at
The opening (1,2) of jaw sinus MS or sinus frontalis FS.Certainly, as above-mentioned, although it is not shown, the outer peripheral surface in main body 100 can be formed with suppression
The film of the expansion of main body 100 processed.
In addition, foley's tube 400 can remove sacculus 420 and execute suction function by distal portions 410, therefore can inhale
Draw maxillary sinus MS or inflammation and impurity in sinus frontalis FS and is discharged to the outside.
Above explanation is only the one of the device for carrying out the present invention for treating nasosinusitis and expanding nasal sinus opening
A embodiment, the present invention is not limited to one embodiment not to depart from of the invention want as recorded in claims below
In the case where purport, various changes are can be performed in those skilled in the art, and it is included in technical idea of the invention.
Claims (1)
1. a kind of device for treating nasosinusitis and expanding nasal sinus opening, the device include:
Main body is made of the Biodegradable material being decomposed after the 1st set time in human body;And
The therapeutic agent of paranasal sinusitis is coated on at least one side of the main body,
The main body coated with the therapeutic agent is inflated after being inserted into reduced nasal sinus opening,
The main body has columnar eyed structure,
The device further includes film, the film surround contraction state the main body, by human body in the 2nd set time
The Biodegradable material being decomposed later is constituted,
2nd time is shorter than the 1st time,
The film is corresponding with the entire length of the main body,
The device further includes foley's tube, and the main body which is coated with the therapeutic agent is inserted into the quilt
The nasal sinus of diminution is open,
The main body is configured to surround the sacculus of the foley's tube, and the main body is swollen by the expansion of the sacculus
It is swollen,
The main body is made of the suture of elasticity,
The device further includes insertion tube, and the main body which is coated with the therapeutic agent is inserted into described reduced
Nasal sinus opening,
The main body is inflated when being discharged from the insertion tube,
The foley's tube is inserted into maxillary sinus or sinus frontalis, and the sacculus for being configured at the opening of maxillary sinus or sinus frontalis is expanded
, the foley's tube can remove the sacculus and execute suction function by distal portions, therefore can attract maxillary sinus or
Inflammation and impurity in sinus frontalis and be discharged to the outside.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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KR10-2016-0086141 | 2016-07-07 | ||
KR1020160086141A KR101697533B1 (en) | 2016-07-07 | 2016-07-07 | Devices for dilating a paranasal sinus opening and for treating sinusitis |
Publications (2)
Publication Number | Publication Date |
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CN107582221A CN107582221A (en) | 2018-01-16 |
CN107582221B true CN107582221B (en) | 2019-06-18 |
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CN201710545351.4A Active CN107582221B (en) | 2016-07-07 | 2017-07-06 | For treating the device of nasosinusitis and expansion nasal sinus opening |
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KR (1) | KR101697533B1 (en) |
CN (1) | CN107582221B (en) |
Families Citing this family (4)
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CN109124837A (en) * | 2018-07-06 | 2019-01-04 | 淮阴工学院 | A kind of encephalic of imitative fish scale-shaped takes bolt bracket |
CN109758278B (en) * | 2019-01-27 | 2020-12-04 | 乐畅医疗器械(上海)有限公司 | Self-expansion nasal sinus support and taking and placing device thereof |
KR20210114739A (en) | 2020-03-11 | 2021-09-24 | 주식회사 에보레이 | Apparatus for treating otorhinolaryngological disease |
KR102222588B1 (en) * | 2020-06-18 | 2021-03-05 | 한국광기술원 | Led patch combination fusion stent |
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CN1349831A (en) * | 2001-11-28 | 2002-05-22 | 周星 | Marmen pipe as mycteric support mold |
JP2004113441A (en) * | 2002-09-26 | 2004-04-15 | Ube Ind Ltd | Graft for stent |
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US10406332B2 (en) * | 2013-03-14 | 2019-09-10 | Intersect Ent, Inc. | Systems, devices, and method for treating a sinus condition |
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EP2023271A2 (en) * | 2007-08-06 | 2009-02-11 | Carestream Health, Inc. | Linear structure verification in medical applications |
CN102740920A (en) * | 2009-12-29 | 2012-10-17 | 阿克拉伦特公司 | System for treating target tissue within the eustachian tube |
CN102988122A (en) * | 2012-11-13 | 2013-03-27 | 浦易(上海)生物技术有限公司 | Prosthetic system for treating nasosinusitis or allergic rhinitis |
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KR101697533B1 (en) | 2017-02-13 |
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