CN107570099A - A kind of tank pressure control device of parallel reactor - Google Patents

A kind of tank pressure control device of parallel reactor Download PDF

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Publication number
CN107570099A
CN107570099A CN201710898091.9A CN201710898091A CN107570099A CN 107570099 A CN107570099 A CN 107570099A CN 201710898091 A CN201710898091 A CN 201710898091A CN 107570099 A CN107570099 A CN 107570099A
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China
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tank
control device
surge flask
reactor
pressure
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CN201710898091.9A
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CN107570099B (en
Inventor
唐寅
张明
杭海峰
张剑坤
马文峰
郭美锦
庄英萍
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GUOQIANG BIOCHEMICAL ENGINEERING EQUIPMENT Co Ltd SHANGHAI
East China University of Science and Technology
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GUOQIANG BIOCHEMICAL ENGINEERING EQUIPMENT Co Ltd SHANGHAI
East China University of Science and Technology
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Abstract

The invention discloses a kind of tank pressure control device of parallel reactor, including:Several reactor tank air inlet pipelines and gas exhaust piping, the air inlet pipeline and gas exhaust piping are set in each reactor tank;Surge flask, the gas exhaust piping of all reactor tanks are communicated to the surge flask;Pressure detection mechanism, to measure the real-time pressure value in the surge flask;Exhaust regulating valve, connected with the surge flask.The tank pressure control device of parallel reactor further comprises and queued the manual bypass valve and safety relief valve that regulating valve is arranged in parallel.Reactor tank coordinates pressure detection mechanism and exhaust regulating valve to be adjusted with surge flask UNICOM.Because row buffering is entered in the exhaust for summarizing each reactor tank so that the fluctuating range of gas pressure reduces, and is advantageous to centralized detecting, improves the sensitivity of control, so as to lift overall control accuracy.It ensure that the uniformity changed between each reactor tank.Reach the tank pressure of each tank mutually to balance unanimously.

Description

A kind of tank pressure control device of parallel reactor
Technical field
The present invention relates to field of microbial culture technology, the tank pressure control device of specially a kind of parallel reactor.
Background technology
In microbial culture medium, dissolved oxygen concentration is an important finger for reflecting microbial cultivation process metabolic characteristics Mark, is the result mutually balanced between oxygen supply condition and oxygen consumption condition.Wherein oxygen supply condition depends primarily on equipment in itself, including Ventilation, stirring and tank pressure.For other gas solubilities, tank pressure and an important factor in order, tank pressure is except to gas Solubility has a direct impact, and then oxyty is had an impact, and further metabolic process is had an impact.To parallel reaction For device system, such as to be changed by dissolved oxygen concentration in incubation, so as to study the metabolic alterations difference between different tanks, The stabilization for just needing to maintain each tank tank pressure as far as possible, to reduce the influence to dissolved oxygen concentration, makes experimental result with consistent with each other The change of metabolic process can truly be reflected, improve the reliability of experimental result.
Due to the characteristic of microorganism, its incubation was both influenceed by external environmental condition, also interior in heredity by it The influence of characteristic, its incubation can not repeat completely.Therefore, in its culture process optimization process, using parallel culture Method, by eliminating system deviation, comparativity and the higher result of study of confidence level can be obtained.And present parallel reactor Problems be present in the voltage-controlled system of tank:
It is the general small volume of each reactor tank in parallel reactor first, stability contorting tank pressure more difficult.And If using miniature regulator to improve precision, although more stable reliable, due to more or less in incubation It can be discharged with a small amount of liquid medium of exhaust clip band, the channel blockage of miniature regulator can be caused, and then pressure control can be caused to lose Effect.
Next to that be usually that the tank pressure of each reactor tank is individually controlled in existing equipment, generally use detection tank Pressure, the size of feedback regulation capacity and air inlet reach balance, to realize the regulation and control of tank pressure.This control device can typically produce The mutual deviation of raw certain each reactor is systematic error, and the systematic error Producing reason is:Each tank sensor detection The difference of the degree of accuracy;The difference of each tank transducer signal pick-up precision;The difference of each reactor control result;Each reactor is to tank Press the asynchronous of the wave time of control result;Detected when needs go out gas in each reactor in exhaust regulating valve leading When, it is drawn the flow capacity limited on reactor and interferes, influences tank pressure control stability, and this interference is with each anti- Answer device circulating sampling and cause circulation to disturb.
The content of the invention
It is an object of the invention to provide a kind of tank pressure control device of parallel reactor, it is possible to achieve between each retort Tank flatten weighing apparatus.
Technical scheme provided by the invention is as follows:A kind of tank pressure control device of parallel reactor, including:
Surge flask, provided with air inlet pipeline and gas exhaust piping, the gas exhaust pipings of all reactor tanks is communicated to described Surge flask, primary exhaust conduit is additionally provided with the surge flask, exhaust regulating valve is provided with the primary exhaust conduit;And
Pressure detection mechanism, to measure the real-time pressure value in the surge flask.
The gas exhaust piping of each reactor tank with surge flask UNICOM, separately draws primary exhaust conduit on surge flask, and at it On be provided with exhaust regulating valve, pressure detection mechanism coordinates the exhaust regulating valve in primary exhaust conduit to adjust extraction flow It is whole.Because row buffering is entered in the exhaust for summarizing each reactor tank so that the fluctuating range of gas pressure reduces, and is advantageous to examine Survey, the sensitivity of control is improved, so as to lift overall control accuracy.Solve when individually progress tank is voltage-controlled processed simultaneously during The asynchronous problem of wave time, and each reactor tank cause the circulation to the pressure observing and controlling of each tank to disturb to exhaust cycle sampling.I.e. Make slightly to fluctuate, also because each tank is synchronous fluctuation, it is ensured that the uniformity changed between each other.
The gas exhaust piping of each reactor tank collects into buffer container, as long as pipeline is thick enough, keeps certain condensate drain slope Degree, just it is enough to ignore gas flow resistance and condensation fluid column pressure in pipeline, reaches the tank pressure of each tank and mutually balance unanimously. And gas via each gas exhaust piping enter surge flask in, wherein entrainment with condensation drop can because flow velocity reduction rest on it is slow Rush in bottle, can so ensure that the work of exhaust regulating valve in its Subsequent passes is unaffected.
It is to complete the control for several reactor tank tank pressures by an equipment and one group of control and detection device, Device cost has not only been saved, observing and controlling points has been also greatly reduced, so as to reduce fault rate, reduces maintenance cost.
Preferably, secondary gas exhaust piping is further provided with the surge flask;The secondary gas exhaust piping is provided with manual bypass Valve.So that when automatic control is broken down or flow is inadequate, manually bypass valve is adjusted manually.
Preferably, pressure relief pipe is further provided with the surge flask, the pressure relief pipe is provided with safety relief valve.With The tank pressure control device tank of parallel reactor is avoided to press through height.
Preferably, the tank pressure control device of parallel reactor further comprises blowoff line, and the blowoff line is from described The bottom of surge flask is led to outside the surge flask, and tapping valve is provided with the blowoff line.To condensate liquid etc. is timely Discharge.
Specifically, the air inlet pipeline in each reactor tank is provided with inlet air flow gauge and check valve.To prevent gas Alter.
Specifically, the pressure detection mechanism is mechanical pressure gauge or pressure sensor.
Specifically, the exhaust regulating valve can be mechanical counterbalance valve.
Specifically, the manual bypass valve is mechanical counterbalance valve.
A kind of tank pressure control device of parallel reactor provided by the invention, it can bring following at least one beneficial to effect Fruit:
1st, reactor tank is with surge flask UNICOM, and then coordinates pressure detection mechanism and exhaust regulating valve to be adjusted. Because row buffering is entered in the exhaust for summarizing each reactor tank so that the fluctuating range of gas pressure reduces, while employs collection Middle detection, the relative sensitivity for improving control, so as to lift overall control accuracy.
2nd, the asynchronous problem of wave time during solving when individually progress tank is voltage-controlled processed, and needing Tail gas measuring When to each reactor tank exhaust cycle sampling cause the circulation to the voltage-controlled system of each tank to disturb.Even if tank pressure slightly fluctuates, each tank It is synchronous fluctuation, i.e., parallel control is carried out to tank pressure, it is ensured that the uniformity changed between each reactor tank.
3rd, the gas exhaust piping of each reactor tank collects into buffer container, as long as pipeline is thick enough, keeps certain condensate drain The gradient, just it is enough to ignore gas flow resistance and condensation fluid column pressure in pipeline, the tank pressure of each tank is reached mutually balance one Cause.
4th, gas enters in surge flask via each gas exhaust piping, wherein entrainment can stop with the drop condensed because flow velocity reduces Stay in surge flask, can so ensure that the work of exhaust regulating valve in its Subsequent passes is unaffected.
5th, it is to complete the control for several reactor tank tank pressures by a tank body and one group of control and detection device System, has not only saved device cost, also greatly reduces observing and controlling points, so as to reduce fault rate, reduces maintenance cost.
Brief description of the drawings
Below by a manner of clearly understandable, preferred embodiment is described with reference to the drawings, it is voltage-controlled to the tank of parallel reactor Above-mentioned characteristic, technical characteristic, advantage and its implementation of device processed are further described.
Fig. 1 is the tank pressure control device schematic diagram of the parallel reactor of the present invention.
Drawing reference numeral explanation:100th, reactor tank, 200, air inlet pipeline, 210, mass flowmenter, 220, spinner flowmeter, 230th, check valve, 300, stirring motor, 310, agitating paddle, 320, speed detector, 400, gas exhaust piping, 500, surge flask, 510th, automatic control exhaust regulating valve, 511, pressure sensor, 512, primary exhaust conduit, 520, mechanical counterbalance valve, 530, manual bypass Valve, 540, safety relief valve, 550, blowoff line.
Embodiment
In order to illustrate more clearly about the embodiment of the present invention or technical scheme of the prior art, control is illustrated below The embodiment of the present invention.It should be evident that drawings in the following description are only some embodiments of the present invention, for For those of ordinary skill in the art, on the premise of not paying creative work, other can also be obtained according to these accompanying drawings Accompanying drawing, and obtain other embodiments.
To make simplified form, part related to the present invention is only schematically show in each figure, their not generations Its practical structures as product of table.
Embodiment one
As shown in figure 1, the present embodiment discloses a kind of tank pressure control device of parallel reactor, including:With reactor tank 100 The air inlet pipeline 200 and gas exhaust piping 400 of connection, surge flask 500, pressure detection mechanism and exhaust regulating valve.
Reactor tank 100 is provided with air inlet pipeline 200 with gas exhaust piping 400 with intake and exhaust, and each reactor tank 100 is at least One group is set to enter outlet pipe, wherein all outlet pipes 400 are communicated to surge flask 500, and pressure detection mechanism is for slow The pressure rushed in bottle 500 is detected, and a primary exhaust conduit 512 is separately drawn on surge flask 500, and exhaust regulating valve is arranged on main row On air pipe 512, to adjust the pressure in all reactor tanks 100 by surge flask 500.By people manually or controlling organization Effect control exhaust regulating valve action, i.e., from automatic control exhaust regulating valve 510 or mechanical counterbalance valve as illustrated in the drawing 520 etc..Exemplary, pressure detection mechanism can select mechanical pressure gauge or pressure sensor 511.
The control units such as the control system of this tank pressure control device and corresponding software can both be integrated in parallel reactor In switch board, it can also be integrated in this tank pressure control device.
Embodiment two
As shown in figure 1, on the basis of embodiment one, from automatic control exhaust regulating valve 510 or mechanical counterbalance valve 520 it Afterwards, the one or more in following valve arrangement can also be increased.
(1) a secondary gas exhaust piping is separately drawn on surge flask 500, manual bypass valve 530 is provided with, in extraction flow When deficiency or the automatic control of exhaust regulating valve 510 or 520 are broken down, manually valve bypass valve 530 it can adjust manually.Hand Dynamic bypass valve can also use the valve of the forms such as mechanical counterbalance valve.
(2) pressure relief pipe is separately drawn on surge flask 500, is provided with safety relief valve 540.It can so avoid Danger during the tank pressure superelevation of parallel reactor.
Embodiment three
As shown in figure 1, on the basis of embodiment one or two, the tank pressure control device of parallel reactor further comprises arranging Dirty pipeline 550, blowoff line 550, draw, and connected with surge flask 500, the blowoff line 550 from the bottom of surge flask 500 On be provided with tapping valve.When the liquid and exhaust condensate liquid carried secretly with each gas exhaust piping run up to certain depth, Ke Yiqi Dynamic tapping valve via blowoff line to excluding.
Air inlet pipeline 200 is provided with inlet air flow gauge and check valve 230.Wherein there is inlet air flow gauge to select quality Flowmeter 210 and/or spinner flowmeter 220.The design of check valve 230 is in order to avoid gas is altered.
It should be noted that above-described embodiment can independent assortment as needed.Described above is only the preferred of the present invention Embodiment, it is noted that for those skilled in the art, do not departing from the premise of the principle of the invention Under, some improvements and modifications can also be made, these improvements and modifications also should be regarded as protection scope of the present invention.

Claims (9)

1. a kind of tank pressure control device of parallel reactor, the tank pressure for each reactor tank to parallel reactor is adjusted Control, it is characterised in that including:
Surge flask, provided with air inlet pipeline and gas exhaust piping;The gas exhaust piping of all reactor tanks is communicated to the buffering The air inlet pipeline of bottle enters surge flask, is additionally provided with primary exhaust conduit on the surge flask, the row of being provided with the primary exhaust conduit Gas regulating valve;And
Pressure detection mechanism, to measure the real-time pressure value in the surge flask.
2. the tank pressure control device of parallel reactor according to claim 1, it is characterised in that:Further comprise control machine Structure, the controlling organization control the action of the exhaust regulating valve by the measurement result of the pressure detection mechanism.
3. the tank pressure control device of parallel reactor according to claim 2, it is characterised in that:The surge flask enterprising one Step is provided with secondary gas exhaust piping;The secondary gas exhaust piping is provided with manual bypass valve.
4. the tank pressure control device of parallel reactor according to claim 1, it is characterised in that:The surge flask enterprising one Step is provided with pressure relief pipe, and the pressure relief pipe is provided with safety relief valve.
5. the tank pressure control device of parallel reactor according to claim 1, it is characterised in that:Further comprise blow-off pipe Road, the blowoff line are led to outside the surge flask from the bottom of the surge flask, and discharge opeing is provided with the blowoff line Valve.
6. according to the tank pressure control device of any described parallel reactors of claim 1-5, it is characterised in that:Each reactor Air inlet pipeline on tank is provided with inlet air flow gauge and check valve.
7. the tank pressure control device of parallel reactor according to claim 1, it is characterised in that:The pressure detection mechanism For mechanical pressure gauge or pressure sensor.
8. the tank pressure control device of parallel reactor according to claim 6, it is characterised in that:The exhaust regulating valve is Mechanical counterbalance valve.
9. the tank pressure control device of parallel reactor according to claim 3, it is characterised in that:The manual bypass valve is Mechanical counterbalance valve.
CN201710898091.9A 2017-09-28 2017-09-28 Tank pressure control device of parallel reactor Active CN107570099B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110538620A (en) * 2018-11-14 2019-12-06 北京北方华创微电子装备有限公司 Pressure control system and pressure control method of reaction chamber

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CN103381352A (en) * 2013-07-25 2013-11-06 无锡意凯自动化技术有限公司 Nitrogen pressurization device for parallel reactor
CN103418327A (en) * 2013-07-25 2013-12-04 无锡意凯自动化技术有限公司 Vacuum-pumping device for parallel reactors
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110538620A (en) * 2018-11-14 2019-12-06 北京北方华创微电子装备有限公司 Pressure control system and pressure control method of reaction chamber

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