CN107550463A - One kind is used for living animal body-sensing mechanical force stimulating system - Google Patents
One kind is used for living animal body-sensing mechanical force stimulating system Download PDFInfo
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- CN107550463A CN107550463A CN201710855201.3A CN201710855201A CN107550463A CN 107550463 A CN107550463 A CN 107550463A CN 201710855201 A CN201710855201 A CN 201710855201A CN 107550463 A CN107550463 A CN 107550463A
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- 230000004936 stimulating effect Effects 0.000 title claims abstract description 35
- 241001465754 Metazoa Species 0.000 title claims abstract description 19
- 238000013519 translation Methods 0.000 claims abstract description 25
- 230000001105 regulatory effect Effects 0.000 claims abstract description 11
- 210000004556 brain Anatomy 0.000 claims abstract description 4
- 230000000638 stimulation Effects 0.000 claims description 21
- 238000001514 detection method Methods 0.000 claims description 15
- 210000004081 cilia Anatomy 0.000 claims description 14
- 238000013481 data capture Methods 0.000 claims description 4
- 230000005611 electricity Effects 0.000 claims description 4
- 238000002474 experimental method Methods 0.000 abstract description 10
- 238000011160 research Methods 0.000 abstract description 10
- 210000000653 nervous system Anatomy 0.000 abstract description 8
- 238000005516 engineering process Methods 0.000 abstract description 3
- 238000010276 construction Methods 0.000 abstract description 2
- 238000002610 neuroimaging Methods 0.000 abstract description 2
- 238000012634 optical imaging Methods 0.000 abstract description 2
- 210000004092 somatosensory cortex Anatomy 0.000 abstract description 2
- 230000001360 synchronised effect Effects 0.000 abstract description 2
- 238000000034 method Methods 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 238000010586 diagram Methods 0.000 description 2
- 241000282693 Cercopithecidae Species 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000005621 ferroelectricity Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000008058 pain sensation Effects 0.000 description 1
- 230000009023 proprioceptive sensation Effects 0.000 description 1
- 238000013515 script Methods 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 230000009897 systematic effect Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
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Abstract
The invention belongs to live body mechanical force stimulating technology field, is specially that one kind is used for living animal body-sensing mechanical force stimulating system.The stimulating system includes：Computer, data collecting card, D.C. regulated power supply, DC relay, mechanical force stimulating apparatus（It is detected pen, D translation platform and standing finish and formed by direct current push-pull electromagnet, mechanical force）., it is necessary to which the intensity and time that are stimulated for mechanical force are precisely controlled in the correlative study of animal body-sensing, and synchronous matching signal acquiring system is needed to be stimulated.Show that this stimulating system coordinates endogenous signal optical imaging system by the experiment of multiple living animal brain imaging, stable brain somatosensory cortex specific reaction can be obtained, its stability has reached scientific research requirements with applicability；Moreover, system cost is cheap, simple in construction, easy to use, time precision is high, the programming Control that can be stimulated, can be widely applied to the research field of body-sensing nervous system.
Description
Technical field
The invention belongs to live body mechanical force stimulating technology field, is specially that a kind of living animal body-sensing mechanical force that is used for stimulates
System.
Background technology
Among the research of nervous system, body-sensing nervous system is an important field of research, its packet handled
The polyesthesia information such as tactile, pressure sensation, the sense of heat, the pain sensation and proprioception has been included, wherein, mechanical force is stimulated in body-sensing nervous system
In the reaction induced for many years be always body-sensing systematic research emphasis.By stimulating induced god for mechanical force
It is reacted it is recognized that mechanical force is in the information process and mechanism of body-sensing system, can deepen for body-sensing nervous system
The even understanding of sensory nervous system and understanding, either have important in basic scientific research, medical science or engineering science
Theory value and Practical significance.
However, in body-sensing nervous system is studied, traditional mechanical force stimulating method generally stimulates the control of dynamics and time
Not accurate enough, speed heterogeneity is made, stability is poor, the defects such as automaticity is low.And these problems have all had a strong impact on machinery
The correlative study result that power stimulates, waste of experimenter's time and efforts in experimentation being caused, experimental data fluctuation is serious,
The more low consequence of experiment conclusion confidence level.Therefore, living animal body-sensing mechanical force stimulating system proposed by the present invention realizes machine
The Automated condtrol that tool power stimulates, simple to operate, stimulation time and strength control are accurate, and stability is good, easy to use, autgmentability
It is strong and cheap, there is good practicality and generalization.
The content of the invention
It is an object of the invention to provide the living animal body-sensing mechanical force that is used for that a kind of cost is relatively low, autgmentability is strong to stimulate system
System.
Provided by the present invention for living animal body-sensing mechanical force stimulating system, including：Computer, data collecting card, direct current
Voltage-stabilized power supply, DC relay, mechanical force stimulating apparatus；Mechanical force stimulating apparatus includes：Direct current push-pull electromagnet, mechanical force
Detection pen, D translation platform, standing finish are some.Its structure is as depicted in figs. 1 and 2.Wherein, the D translation platform is by X-axis
Translation stage, Y-axis translation stage and the combination of Z axis lifting platform are formed, and D translation platform can move in space three-dimensional；Direct current pushes away
Pull-type electromagnet is fixed on the Z axis lifting platform of D translation platform, and mechanical force detects pen and passes through fix bar and fixed screw and electricity
Magnet shaft is into being fixedly connected；The leading section of mechanical force detection pen stimulates cilium for mechanical force；Computer, data collecting card, direct current are steady
It is connected between voltage source, DC relay and mechanical force stimulating apparatus by power line and wire；Computer and data collecting card
Connected by USB data line；By the data acquisition card driver control data capture card of computer end in two numeral outputs
Mouth difference output digit signals " 1 " and " 0 "（Or " 0 " and " 0 "）, to produce 5V（Or 0V）Voltage, to control direct current relay respectively
Device is opened（Or close）；Two data signals are respectively connected to DC relay（Control voltage is 5V）The input of input circuit and defeated
Go out end.The output end of DC relay is series at a D.C. regulated power supply that can provide 12V voltages and the plug-type electromagnetism of direct current
In ferroelectricity road, so as to which DC relay is opened（Or close）The drawing of push-pull electromagnet will be caused（Or push away）, produce one vertically
The linear motion of set a distance so that the mechanical force detection pen and stimulation cilium being fixed on electromagnet shaft are backward（Or forward）Fortune
It is dynamic, stimulated so as to which the stimulation site to front end produces mechanical force.
In the system, the direct current push-pull electromagnet is adapted to D.C. regulated power supply and relay, i.e., the latter two
Output voltage and current parameters match with push-pull electromagnet.
Produce the distance of mechanical force stimulation and speed depends on the design parameter of direct current push-pull electromagnet, according to actual feelings
Condition can be exchanged.
In the system, the size matching of the shaft diameter of the electromagnet and the diameter of detection pen；Mechanical force detects pen
Fixed by the fix bar and corresponding screw that meet electromagnet shaft size and detection penholder size；In use, can be according to reality
Situation changes various sizes of electromagnet and detection pen, and exchanges different fix bars and be fixed.
In order to more accurately control the stimulation site of push-pull electromagnet, direct current push-pull electromagnet is consolidated by screw
Due on the D translation platform in optical table, including X-axis translation stage, Y-axis translation stage and Z axis lifting platform.In stimulation test,
D translation platform can move in space three-dimensional, so as to which accurate adjustment mechanical force stimulates the locus of cilium.
Because the region for testing body among the scientific research of reality, receiving to stimulate and size are often different, therefore, this
In mechanical force stimulating system, involved direct current push-pull electromagnet, D.C. regulated power supply, DC relay, is by testing
What the region of body and size were determined.According to the region of experiment body and of different sizes, it is necessary to select the straight of varying strength and speed
Push-pull electromagnet is flowed, so as to need corresponding D.C. regulated power supply and DC relay.By selecting different the said equipments,
Mechanical force stimulation study available for various living animals.Further, since the difference of experiment demand is, it is necessary to select different mechanical forces
The mechanical force detection pen of degree is stimulated, and in this mechanical force stimulating system, involved mechanical force detection pen can be according to reality
The difference of demand is tested, installing the mechanical force detection pen of different mechanical force intensitys is stimulated, so as to realize different mechanical force intensitys
Stimulation.
This mechanical force stimulating system can compared with existing mechanical force stimulating system, by be fixed on push-pull electromagnet
The mechanical force detection pen of replacing, the intensity that can stimulate mechanical force is more accurate, meanwhile, mechanical force detects the fixing device of pen
So that mechanical force stimulates the replacing of cilium more convenient, so as to different mechanical forces stimulation using more convenient；By using electricity
The data collecting card of brain control, it is possible to achieve mechanical force stimulates accurate control and automatic programming operation in time；Make
Allowing to precise fine-adjustment mechanical force with three translation stages stimulates the stimulation sites of cilium.
, it is necessary to which the intensity and time that are stimulated for mechanical force are precisely controlled in the correlative study of animal body-sensing, and
Synchronous matching signal acquiring system is needed to be stimulated.Shown by the experiment of multiple living animal brain imaging, this stimulating system
Coordinate endogenous signal optical imaging system, stable brain somatosensory cortex specific reaction can be obtained, its stability is with being applicable
Property reaches scientific research requirements；Moreover, system cost is cheap, simple in construction, easy to use, time precision is high, can be stimulated
Programming Control, the research field of body-sensing nervous system is can be widely applied to, be such as used for various mouse, cat, the body of monkey living animal
The research of sense.
Brief description of the drawings
Fig. 1 is living animal body-sensing mechanical force stimulating system structural diagrams.
Fig. 2 is mechanical force stimulating apparatus structural diagrams.
Label in figure：1 is computer, and 2 be data collecting card, and 3 be DC relay, and 4 be D.C. regulated power supply, and 5 be machinery
Power stimulating apparatus, 6 be stimulation site；7 be X-axis translation stage, and 8 be Y-axis translation stage, and 9 be Z axis lifting platform, and 10 be D translation
Platform, 11 be direct current push-pull electromagnet, and 12 be fix bar, and 13 be fixed screw, and 14 be that mechanical force detects pen, and 15 be that mechanical force is pierced
Swash cilium.
Embodiment
Living animal body-sensing mechanical force stimulating system is further described below by Fig. 1 and Fig. 2.
The system includes（See Fig. 1）：Computer 1, data collecting card 2, DC relay 3, D.C. regulated power supply 4, mechanical force
Stimulating apparatus 5, wherein, mechanical force stimulating apparatus includes（See Fig. 2）：X-axis translation stage 7, Y-axis translation stage 8, Z axis lifting platform 9（Three
Person forms D translation platform 10）, direct current push-pull electromagnet 11, fix bar 12, fixed screw 13, mechanical force detection pen 14, machine
Tool power stimulates cilium 15.
Described direct current push-pull electromagnet, D.C. regulated power supply, DC relay, it is by experiment body in the system
What region and size were determined, it is corresponding straight so as to need by selecting the direct current push-pull electromagnet of varying strength and speed
Voltage-stabilized power supply and DC relay are flowed, mechanical force stimulation can be carried out for region and experiment body of different sizes.It is and of the invention
In, described mechanical force detection pen, determined by experiment demand, by selecting the mechanical force of different mechanical dynamics to detect pen
Stimulated, so as to realize the accurate stimulation of different mechanical force intensitys.
The system for system before use, being assembled and being debugged.First, package system：As requested, each equipment is carried out
Line, it is ensured that electrical communication is normal, and the electric current and voltage stabilization of each equipment；The 2nd, corresponding software program is installed：
The driver of computer terminal installation data capture card and the programming software that data collecting card can be controlled；3rd, machine is debugged
Tool stimulating apparatus：Mechanical force stimulation pen is fixed in the fixed platform of direct current push-pull electromagnet, by adjusting D translation
Platform, mechanical force is stimulated into the stimulation cilium of pen to the stimulated zone of quasi-experiment body, also, adjust cilium to the stimulation area for testing body
The distance between domain, the degree of crook of cilium is moderate when making carry out mechanical force stimulation.
During using the system, first, D.C. regulated power supply is connected, then, using the programming software of computer terminal, control number
According to the output digit signals " 0 " of capture card and " 0 "（Or " 1 " and " 0 "）, to control the "off" of DC relay or " on ",
So as to the power supply of "off" or " on " direct current push-pull electromagnet, make its " remote " or " close ", final realization, which is fixed on, to be pushed away
Mechanical force on pull bar stimulates cilium to stimulate experiment body " stopping " or " progress " mechanical force.
For example, to realize the mechanical force for the 5g that frequency of stimulation is 1Hz stimulates, a length of 0.6s during the stimulation stimulated every time,
Every when a length of 0.4s, common 1min mechanical forces stimulate, then need to fix and install mechanical force intensity on direct current push-pull electromagnet
Pen is detected for 5g mechanical force, then, by adjusting D translation platform, cilium will be stimulated to adjust in the front for stimulating site,
Between distance be slightly less than direct current push-pull electromagnet process（About 5mm）.Then, the programmed scripts positioned at computer end are write,
Two port output digit signals " 0 " of control data capture card and " 0 ", timing 0.6s, " 1 " and " 0 " then is exported, timing
0.4s, the stimulation cycle 60 times, you can.
The invention provides one kind to be used for living animal body-sensing mechanical force stimulating system, implement the thinking of the program with
Method is a lot, it is noted that for those skilled in the art, on the premise of this programme principle is not departed from, can make very
Improve, these improvement are considered as protection scope of the present invention more.
Claims (3)
1. one kind is used for living animal body-sensing mechanical force stimulating system, it is characterised in that including：Computer, data collecting card, direct current
Voltage-stabilized power supply, DC relay, mechanical force stimulating apparatus；Mechanical force stimulating apparatus includes：Direct current push-pull electromagnet, mechanical force
Detection pen, D translation platform, standing finish are some；Wherein, the D translation platform is by X-axis translation stage, Y-axis translation stage and Z axis
Lifting platform combination is formed, and D translation platform can move in space three-dimensional；Direct current push-pull electromagnet is fixed on three-dimensional flat
On the Z axis lifting platform of moving stage, mechanical force detects pen by fix bar and fixed screw and electromagnet shaft into being fixedly connected；Mechanical force
Detect the leading section of pen stimulates cilium for mechanical force；Computer, data collecting card, D.C. regulated power supply, DC relay and machine
It is connected between tool power stimulating apparatus by power line and wire；Computer is connected with data collecting card by USB data line；Pass through electricity
The data acquisition card driver control data capture card at brain end in two digital outputs difference output digit signals " 1 " and
" 0 ", to produce 5V or 0V voltages, to control DC relay to open respectively or close；Two data signals are respectively connected to direct current relay
The input and output end of the input circuit of device；The output end of DC relay is series at a direct current that can provide 12V voltages
In voltage-stabilized power supply and direct current push-pull electromagnet circuit；So as to, the unlatching of DC relay or close, cause push-pull electromagnet
Draw or push away, produce the linear motion of certain distance vertically so that mechanical force detection pen and the thorn being fixed on electromagnet shaft
Sharp cilium posteriorly or anteriorly moves, and is stimulated so as to which the stimulation site to front end produces mechanical force.
2. according to claim 1 be used for living animal body-sensing mechanical force stimulating system, it is characterised in that the direct current pushes away
Pull-type electromagnet is adapted to D.C. regulated power supply and relay, i.e. the output voltage of the latter two and current parameters and plug-type electricity
Magnet matches.
3. according to claim 1 be used for living animal body-sensing mechanical force stimulating system, it is characterised in that the direct current pushes away
The size matching of the diameter of pull-type electromagnet shaft diameter and mechanical force detection pen.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710855201.3A CN107550463A (en) | 2017-09-20 | 2017-09-20 | One kind is used for living animal body-sensing mechanical force stimulating system |
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| CN201710855201.3A CN107550463A (en) | 2017-09-20 | 2017-09-20 | One kind is used for living animal body-sensing mechanical force stimulating system |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109700438A (en) * | 2019-02-27 | 2019-05-03 | 复旦大学 | A kind of compound somatosensory stimulator for giving experimental animal mechanical force and high temperature |
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| JPH10127721A (en) * | 1996-10-28 | 1998-05-19 | Advance Co Ltd | Stimulator |
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| CN109700438A (en) * | 2019-02-27 | 2019-05-03 | 复旦大学 | A kind of compound somatosensory stimulator for giving experimental animal mechanical force and high temperature |
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